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Conserved domains on  [gi|1079631259|emb|SCW51738|]
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IstB-like ATP binding protein, partial [Ruminococcaceae bacterium YRB3002]

Protein Classification

ATP-binding protein( domain architecture ID 11445237)

ATP-binding protein with an AAA (ATPases Associated with various cellular Activities) domain, similar to the ATPase region of Aquifex aeolicus DnaC helicase loader and to Mycobacterium tuberculosis putative ATP-binding protein Rv3427c in insertion sequence

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
2-142 2.95e-42

DNA replication protein DnaC [Replication, recombination and repair];


:

Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 140.30  E-value: 2.95e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVNGLVKPSCLIIDEIGRCVFNKENTRLFF 81
Cdd:COG1484   104 LLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNELKEARADGRLERLLKRLAKVDLLILDELGYLPLDAEGAELLF 183

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1079631259  82 DMVDRRYSKegpNSMVFTSNLMPDKWCEFFNEDESLKCALDRIFDDAVVYMIQGESYRGKN 142
Cdd:COG1484   184 ELISDRYER---RSTIITSNLPFSEWGEVFGDPTLATAILDRLVHHAHIIELKGESYRLKE 241
 
Name Accession Description Interval E-value
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
2-142 2.95e-42

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 140.30  E-value: 2.95e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVNGLVKPSCLIIDEIGRCVFNKENTRLFF 81
Cdd:COG1484   104 LLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNELKEARADGRLERLLKRLAKVDLLILDELGYLPLDAEGAELLF 183

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1079631259  82 DMVDRRYSKegpNSMVFTSNLMPDKWCEFFNEDESLKCALDRIFDDAVVYMIQGESYRGKN 142
Cdd:COG1484   184 ELISDRYER---RSTIITSNLPFSEWGEVFGDPTLATAILDRLVHHAHIIELKGESYRLKE 241
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 2-142 1.17e-36

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 125.66  E-value: 1.17e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVNGLVKPSCLIIDEIGRCVFNKENTRLFF 81
Cdd:NF038214   95 LLGPPGTGKTHLAIALGYAACRQGYRVRFTTAADLVEQLAQARADGRLGRLLRRLARYDLLIIDELGYLPFSREGANLLF 174

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1079631259  82 DMVDRRYSKegpNSMVFTSNLMPDKWCEFFnEDESLKCA-LDRIFDDAVVYMIQGESYRGKN 142
Cdd:NF038214  175 ELIADRYER---GSTIITSNLPFSEWGEVF-GDPTLAAAiLDRLVHHAHILELKGESYRLKE 232
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
 1-142 1.97e-32

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 115.24  E-value: 1.97e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   1 AFIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVNGLVKPSCLIIDEIGRCVFNKENTRLF 80
Cdd:pfam01695  96 VLLGPPGVGKTHLAIALGVEACRAGYSVRFTSAADLVNQLKRAHGDGKLTRKLQQLLKPDVLILDEWGYLPLDQAEANLL 175

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1079631259  81 FDMVDRRYSKegpNSMVFTSNLMPDKWCEFFNeDESLKCA-LDRIFDDAVVYMIQGESYRGKN 142
Cdd:pfam01695 176 FQVISKRYEH---RSIILTSNLPFGEWGQVFG-DAVLATAiLDRLLHHCHIVPIKGESYRLKT 234
PRK09183 PRK09183
transposase/IS protein; Provisional
 2-141 1.50e-31

transposase/IS protein; Provisional


Pssm-ID: 181681  Cd Length: 259  Bit Score: 113.26  E-value: 1.50e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVN-GLVKPSCLIIDEIGRCVFNKENTRLF 80
Cdd:PRK09183  107 LLGPSGVGKTHLAIALGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQrGVMAPRLLIIDEIGYLPFSQEEANLF 186

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1079631259  81 FDMVDRRYSKegpNSMVFTSNLMPDKWCEFFNEDESLKCA-LDRIFDDAVVYMIQGESYRGK 141
Cdd:PRK09183  187 FQVIAKRYEK---GSMILTSNLPFGQWDQTFAGDAALTSAmLDRLLHHSHVVQIKGESYRLK 245
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 2-106 6.54e-12

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 59.47  E-value: 6.54e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVNGLV----KPSCLIIDEIGR--CVFNKE 75
Cdd:cd00009    24 LYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFELaekaKPGVLFIDEIDSlsRGAQNA 103

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1079631259  76 NTRLFFDMVDRRYSKEGPNSMVFTSNLMPDK 106
Cdd:cd00009   104 LLRVLETLNDLRIDRENVRVIGATNRPLLGD 134
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 1-106 3.03e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 49.68  E-value: 3.03e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259    1 AFIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVNGL---------------VKPSCLIID 65
Cdd:smart00382   6 LIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGsgelrlrlalalarkLKPDVLILD 85

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1079631259   66 EIGRC---VFNKENTRLFFDMVDRRYSKEGPNSMVFTSNLMPDK 106
Cdd:smart00382  86 EITSLldaEQEALLLLLEELRLLLLLKSEKNLTVILTTNDEKDL 129
 
Name Accession Description Interval E-value
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
2-142 2.95e-42

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 140.30  E-value: 2.95e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVNGLVKPSCLIIDEIGRCVFNKENTRLFF 81
Cdd:COG1484   104 LLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNELKEARADGRLERLLKRLAKVDLLILDELGYLPLDAEGAELLF 183

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1079631259  82 DMVDRRYSKegpNSMVFTSNLMPDKWCEFFNEDESLKCALDRIFDDAVVYMIQGESYRGKN 142
Cdd:COG1484   184 ELISDRYER---RSTIITSNLPFSEWGEVFGDPTLATAILDRLVHHAHIIELKGESYRLKE 241
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 2-142 1.17e-36

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 125.66  E-value: 1.17e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVNGLVKPSCLIIDEIGRCVFNKENTRLFF 81
Cdd:NF038214   95 LLGPPGTGKTHLAIALGYAACRQGYRVRFTTAADLVEQLAQARADGRLGRLLRRLARYDLLIIDELGYLPFSREGANLLF 174

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1079631259  82 DMVDRRYSKegpNSMVFTSNLMPDKWCEFFnEDESLKCA-LDRIFDDAVVYMIQGESYRGKN 142
Cdd:NF038214  175 ELIADRYER---GSTIITSNLPFSEWGEVF-GDPTLAAAiLDRLVHHAHILELKGESYRLKE 232
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
 1-142 1.97e-32

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 115.24  E-value: 1.97e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   1 AFIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVNGLVKPSCLIIDEIGRCVFNKENTRLF 80
Cdd:pfam01695  96 VLLGPPGVGKTHLAIALGVEACRAGYSVRFTSAADLVNQLKRAHGDGKLTRKLQQLLKPDVLILDEWGYLPLDQAEANLL 175

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1079631259  81 FDMVDRRYSKegpNSMVFTSNLMPDKWCEFFNeDESLKCA-LDRIFDDAVVYMIQGESYRGKN 142
Cdd:pfam01695 176 FQVISKRYEH---RSIILTSNLPFGEWGQVFG-DAVLATAiLDRLLHHCHIVPIKGESYRLKT 234
PRK09183 PRK09183
transposase/IS protein; Provisional
 2-141 1.50e-31

transposase/IS protein; Provisional


Pssm-ID: 181681  Cd Length: 259  Bit Score: 113.26  E-value: 1.50e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVN-GLVKPSCLIIDEIGRCVFNKENTRLF 80
Cdd:PRK09183  107 LLGPSGVGKTHLAIALGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQrGVMAPRLLIIDEIGYLPFSQEEANLF 186

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1079631259  81 FDMVDRRYSKegpNSMVFTSNLMPDKWCEFFNEDESLKCA-LDRIFDDAVVYMIQGESYRGK 141
Cdd:PRK09183  187 FQVIAKRYEK---GSMILTSNLPFGQWDQTFAGDAALTSAmLDRLLHHSHVVQIKGESYRLK 245
PRK06526 PRK06526
transposase; Provisional
 2-153 1.65e-24

transposase; Provisional


Pssm-ID: 180607  Cd Length: 254  Bit Score: 94.94  E-value: 1.65e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVNGLVKPSCLIIDEIGRCVFNKENTRLFF 81
Cdd:PRK06526  103 FLGPPGTGKTHLAIGLGIRACQAGHRVLFATAAQWVARLAAAHHAGRLQAELVKLGRYPLLIVDEVGYIPFEPEAANLFF 182

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1079631259  82 DMVDRRYSKegpNSMVFTSNLMPDKWCEFFNEDESLKCALDRIFDDAVVYMIQGESYR--GKNLETYSIATTAN 153
Cdd:PRK06526  183 QLVSSRYER---ASLIVTSNKPFGRWGEVFGDDVVAAAMIDRLVHHAEVISLKGDSYRlkDRDLGRVPAATKTN 253
PRK08181 PRK08181
transposase; Validated
 4-139 1.30e-13

transposase; Validated


Pssm-ID: 136670 [Multi-domain]  Cd Length: 269  Bit Score: 66.11  E-value: 1.30e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   4 GPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVNGLVKPSCLIIDEIGRCVFNKENTRLFFDM 83
Cdd:PRK08181  113 GPPGGGKSHLAAAIGLALIENGWRVLFTRTTDLVQKLQVARRELQLESAIAKLDKFDLLILDDLAYVTKDQAETSVLFEL 192

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1079631259  84 VDRRYSKEgpnSMVFTSNLMPDKWCEFFNEDESLKCALDRIFDDAVVYMIQGESYR 139
Cdd:PRK08181  193 ISARYERR---SILITANQPFGEWNRVFPDPAMTLAAVDRLVHHATIFEMNVESYR 245
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 2-106 6.54e-12

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 59.47  E-value: 6.54e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVNGLV----KPSCLIIDEIGR--CVFNKE 75
Cdd:cd00009    24 LYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFELaekaKPGVLFIDEIDSlsRGAQNA 103

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1079631259  76 NTRLFFDMVDRRYSKEGPNSMVFTSNLMPDK 106
Cdd:cd00009   104 LLRVLETLNDLRIDRENVRVIGATNRPLLGD 134
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 1-106 3.03e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 49.68  E-value: 3.03e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259    1 AFIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREGSVVNGL---------------VKPSCLIID 65
Cdd:smart00382   6 LIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGsgelrlrlalalarkLKPDVLILD 85

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1079631259   66 EIGRC---VFNKENTRLFFDMVDRRYSKEGPNSMVFTSNLMPDK 106
Cdd:smart00382  86 EITSLldaEQEALLLLLEELRLLLLLKSEKNLTVILTTNDEKDL 129
PRK08116 PRK08116
hypothetical protein; Validated
 2-142 1.47e-07

hypothetical protein; Validated


Pssm-ID: 236153 [Multi-domain]  Cd Length: 268  Bit Score: 49.25  E-value: 1.47e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIK-YGREGS--VVNGLVKPSCLIIDEIG--RcvfNKEN 76
Cdd:PRK08116  119 LWGSVGTGKTYLAACIANELIEKGVPVIFVNFPQLLNRIKSTYKsSGKEDEneIIRSLVNADLLILDDLGaeR---DTEW 195

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1079631259  77 TR-LFFDMVDRRYSKEGPnsMVFTSNLMPDKWceffnEDESLKCALDRIFDDAVVYMIQGESYRGKN 142
Cdd:PRK08116  196 AReKVYNIIDSRYRKGLP--TIVTTNLSLEEL-----KNQYGKRIYDRILEMCTPVENEGKSYRKEI 255
PRK07952 PRK07952
DNA replication protein DnaC; Validated
 2-101 3.35e-05

DNA replication protein DnaC; Validated


Pssm-ID: 181180 [Multi-domain]  Cd Length: 244  Bit Score: 42.45  E-value: 3.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGR--EGSVVNGLVKPSCLIIDEIGRCVFNKENTRL 79
Cdd:PRK07952  104 FSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFSNSEtsEEQLLNDLSNVDLLVIDEIGVQTESRYEKVI 183

                          90       100
                  ....*....|....*....|..
gi 1079631259  80 FFDMVDRRYSKEGPNSMVFTSN 101
Cdd:PRK07952  184 INQIVDRRSSSKRPTGMLTNSN 205
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
2-107 3.22e-04

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 39.40  E-value: 3.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FI-GPQGVGKTHLAMAYGRECCLQ--GYKTYFLKATELNQRFSEAIKYGREGSVVNGLVKPSCLIIDEIGRcVFNKENT- 77
Cdd:COG0593    38 FLyGGVGLGKTHLLHAIGNEALENnpGARVVYLTAEEFTNDFINAIRNNTIEEFKEKYRSVDVLLIDDIQF-LAGKEATq 116

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1079631259  78 -RLF--FDMVdrrysKEGPNSMVFTSNLMPDKW 107
Cdd:COG0593   117 eEFFhtFNAL-----REAGKQIVLTSDRPPKEL 144
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
 2-67 7.63e-04

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 37.65  E-value: 7.63e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLqgyKTYFLKATELNQRFS--------EAIKYGREGSvvnglvkPSCLIIDEI 67
Cdd:cd19481    31 LYGPPGTGKTLLAKALAGELGL---PLIVVKLSSLLSKYVgeseknlrKIFERARRLA-------PCILFIDEI 94
PRK12377 PRK12377
putative replication protein; Provisional
 1-101 1.17e-03

putative replication protein; Provisional


Pssm-ID: 183482 [Multi-domain]  Cd Length: 248  Bit Score: 37.89  E-value: 1.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   1 AFIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEAIKYGREG-SVVNGLVKPSCLIIDEIGRCVFNKENTRL 79
Cdd:PRK12377  105 VFSGKPGTGKNHLAAAIGNRLLAKGRSVIVVTVPDVMSRLHESYDNGQSGeKFLQELCKVDLLVLDEIGIQRETKNEQVV 184

                          90       100
                  ....*....|....*....|..
gi 1079631259  80 FFDMVDRRYSKEGPNSMVFTSN 101
Cdd:PRK12377  185 LNQIIDRRTASMRSVGMLTNLN 206
PRK06835 PRK06835
DNA replication protein DnaC; Validated
 2-113 4.39e-03

DNA replication protein DnaC; Validated


Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 36.42  E-value: 4.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECCLQGYKTYFLKATELNQRFSEA-IKYGREGSVVNGLVKpSC--LIIDEIGRCVFNKENTR 78
Cdd:PRK06835  188 FYGNTGTGKTFLSNCIAKELLDRGKSVIYRTADELIEILREIrFNNDKELEEVYDLLI-NCdlLIIDDLGTEKITEFSKS 266

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1079631259  79 LFFDMVDRRYSKegPNSMVFTSNLMPDKWCEFFNE 113
Cdd:PRK06835  267 ELFNLINKRLLR--QKKMIISTNLSLEELLKTYSE 299
RecA-like_CDC48_NLV2_r1-like cd19503
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ...
 2-67 4.53e-03

first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410911 [Multi-domain]  Cd Length: 165  Bit Score: 35.73  E-value: 4.53e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECclqGYKTYFLKA----------TELNQR--FSEAIKYgregsvvnglvKPSCLIIDEI 67
Cdd:cd19503    39 LHGPPGTGKTLLARAVANEA---GANFLSISGpsivskylgeSEKNLReiFEEARSH-----------APSIIFIDEI 102
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 2-67 9.95e-03

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 34.11  E-value: 9.95e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1079631259   2 FIGPQGVGKTHLAMAYGRECclqGYKTYFLKATEL--------NQRFSEAIKYGREGSvvnglvkPSCLIIDEI 67
Cdd:pfam00004   3 LYGPPGTGKTTLAKAVAKEL---GAPFIEISGSELvskyvgesEKRLRELFEAAKKLA-------PCVIFIDEI 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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