|
Name |
Accession |
Description |
Interval |
E-value |
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
2-237 |
0e+00 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 508.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIAARYNLD 81
Cdd:cd19513 1 ITTGSKELDKLLGGGIETGSITELFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 82 PEQVLENVSYARAYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRTDFSGRGELGARQIHLARFLRMLMRLADEFGV 161
Cdd:cd19513 81 GEDVLDNVAYARAYNTDHQMQLLIQASAMMAESRYALLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEFGV 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1585497099 162 AVVITNQVVSSVDGaAAMFNADPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAVFAITENGIAD 237
Cdd:cd19513 161 AVVITNQVVAQVDG-AAMFAGDPKKPIGGNIMAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAVFAITEDGIGD 235
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
1-240 |
2.61e-180 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 496.94 E-value: 2.61e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 1 YLTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIAARYNL 80
Cdd:TIGR02239 77 QLTTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGL 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 81 DPEQVLENVSYARAYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRTDFSGRGELGARQIHLARFLRMLMRLADEFG 160
Cdd:TIGR02239 157 NPEDVLDNVAYARAYNTDHQLQLLQQAAAMMSESRFALLIVDSATALYRTDFSGRGELSARQMHLARFLRSLQRLADEFG 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 161 VAVVITNQVVSSVDGAAAMFNADPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAVFAITENGIADPQE 240
Cdd:TIGR02239 237 VAVVITNQVVAQVDGAGSMFAGDPKKPIGGNIMAHASTTRLSLRKGRGEQRICKIYDSPCLPESEAMFAIYEDGIGDPKE 316
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
1-238 |
2.68e-174 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 479.11 E-value: 2.68e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 1 YLTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIAARYNL 80
Cdd:pfam08423 18 QITTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLCVTCQLPLEMGGGEGKALYIDTEGTFRPERLVAIAERYGL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 81 DPEQVLENVSYARAYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRTDFSGRGELGARQIHLARFLRMLMRLADEFG 160
Cdd:pfam08423 98 DPEDVLDNVAYARAYNSEHQMQLLQQAAAMMSESRFALLIVDSATALYRTDFSGRGELAERQQHLAKFLRTLQRLADEFG 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1585497099 161 VAVVITNQVVSSVDGAAAMFNADPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAVFAITENGIADP 238
Cdd:pfam08423 178 VAVVITNQVVAQVDGAAGMFSGDPKKPIGGHIMAHASTTRLSLRKGRGEQRICKIYDSPCLPESEAVFAIGSGGIIDP 255
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
2-240 |
2.84e-169 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 469.86 E-value: 2.84e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIAARYNLD 81
Cdd:PTZ00035 100 ITTGSTQLDKLLGGGIETGSITELFGEFRTGKTQLCHTLCVTCQLPIEQGGGEGKVLYIDTEGTFRPERIVQIAERFGLD 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 82 PEQVLENVSYARAYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRTDFSGRGELGARQIHLARFLRMLMRLADEFGV 161
Cdd:PTZ00035 180 PEDVLDNIAYARAYNHEHQMQLLSQAAAKMAEERFALLIVDSATALFRVDYSGRGELAERQQHLGKFLRALQKLADEFNV 259
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1585497099 162 AVVITNQVVSSVDGaAAMFNADPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAVFAITENGIADPQE 240
Cdd:PTZ00035 260 AVVITNQVMADVDG-ASMFVADPKKPIGGHIIAHASTTRLSLRKGRGEQRICKIYDSPNLPESEAVFAISEGGIIDAKD 337
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
1-240 |
2.13e-158 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 442.63 E-value: 2.13e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 1 YLTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIAARYNL 80
Cdd:PLN03186 104 QITTGSRELDKILEGGIETGSITEIYGEFRTGKTQLCHTLCVTCQLPLDQGGGEGKAMYIDTEGTFRPQRLIQIAERFGL 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 81 DPEQVLENVSYARAYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRTDFSGRGELGARQIHLARFLRMLMRLADEFG 160
Cdd:PLN03186 184 NGADVLENVAYARAYNTDHQSELLLEAASMMAETRFALMIVDSATALYRTEFSGRGELSARQMHLGKFLRSLQRLADEFG 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 161 VAVVITNQVVSSVDGAAamFNADPK-KPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAVFAITENGIADPQ 239
Cdd:PLN03186 264 VAVVITNQVVAQVDGSA--FFAGPQlKPIGGNIMAHASTTRLALRKGRGENRICKVISSPCLPEAEARFSISSEGVTDVK 341
|
.
gi 1585497099 240 E 240
Cdd:PLN03186 342 D 342
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
2-235 |
2.01e-150 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 418.09 E-value: 2.01e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIAARYNLD 81
Cdd:cd01123 1 ITTGSKELDKLLGGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDRGGGEGKAIYIDTEGTFRPERLRAIAQRFGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 82 PEQVLENVSYARAYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRTDFSGRGELGARQIHLARFLRMLMRLADEFGV 161
Cdd:cd01123 81 PDDVLDNVAYARAFNSDHQTQLLDQAAAMMVESRFKLLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEFGV 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1585497099 162 AVVITNQVVSSVDGaAAMFNADPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAVFAITENGI 235
Cdd:cd01123 161 AVVVTNQVVAQVDG-AMMFAADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAVFAITADGV 233
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
2-237 |
7.26e-141 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 394.03 E-value: 7.26e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIAARYNLD 81
Cdd:cd19514 1 ISTGSTELDKLLGGGIESMSITEVFGEFRTGKTQLSHTLCVTAQLPGSMGGGGGKVAYIDTEGTFRPDRIRPIAERFGVD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 82 PEQVLENVSYARAYNSDHQSQLLIQAAAMMSESN-YSVLIVDSATALYRTDFSGRGELGARQIHLARFLRMLMRLADEFG 160
Cdd:cd19514 81 HDAVLDNILYARAYTSEHQMELLDYVAAKFHEEAvFRLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYN 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1585497099 161 VAVVITNQVVSSVdGAAAMFNADPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAVFAITENGIAD 237
Cdd:cd19514 161 VAVFITNQVTADP-GAAMTFQADPKKPIGGHILAHASTTRISLRKGRGEERIAKIYDSPDLPENEATFAITAGGIAD 236
|
|
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
2-237 |
2.96e-122 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 349.85 E-value: 2.96e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIAARYNLD 81
Cdd:TIGR02238 78 ITTGSQALDGILGGGIESMSITEVFGEFRCGKTQLSHTLCVTAQLPREMGGGNGKVAYIDTEGTFRPDRIRAIAERFGVD 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 82 PEQVLENVSYARAYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRTDFSGRGELGARQIHLARFLRMLMRLADEFGV 161
Cdd:TIGR02238 158 PDAVLDNILYARAYTSEHQMELLDYLAAKFSEEPFRLLIVDSIMALFRVDFSGRGELSERQQKLAQMLSRLNKISEEFNV 237
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1585497099 162 AVVITNQVVSSvDGAAAMFNADPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAVFAITENGIAD 237
Cdd:TIGR02238 238 AVFVTNQVQAD-PGATMTFIADPKKPIGGHVLAHASTTRILLRKGRGEERVAKLYDSPDMPEAEASFQITEGGIAD 312
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
2-237 |
8.27e-118 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 339.83 E-value: 8.27e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIAARYNLD 81
Cdd:PLN03187 108 ITTGSQALDELLGGGIETRCITEAFGEFRSGKTQLAHTLCVTTQLPTEMGGGNGKVAYIDTEGTFRPDRIVPIAERFGMD 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 82 PEQVLENVSYARAYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRTDFSGRGELGARQIHLARFLRMLMRLADEFGV 161
Cdd:PLN03187 188 ADAVLDNIIYARAYTYEHQYNLLLGLAAKMAEEPFRLLIVDSVIALFRVDFTGRGELAERQQKLAQMLSRLTKIAEEFNV 267
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1585497099 162 AVVITNQVVSsvDGAAAMFNADPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAVFAITENGIAD 237
Cdd:PLN03187 268 AVYMTNQVIA--DPGGGMFISDPKKPAGGHVLAHAATIRLMLRKGKGEQRVCKVFDAPNLPEAEAEFQITSGGIMD 341
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
2-237 |
3.14e-117 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 333.95 E-value: 3.14e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIAARYNLD 81
Cdd:cd19515 1 ISTGSKELDKLLGGGIETQAITEVFGEFGSGKTQLCHQLAVNVQLPPEEGGLNGKAVYIDTENTFRPERIMQMAKALGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 82 PEQVLENVSYARAYNSDHQSQLLIQAAAMMSES-NYSVLIVDSATALYRTDFSGRGELGARQIHLARFLRMLMRLADEFG 160
Cdd:cd19515 81 PDEVLDNIYVARAYNSNHQMLLVEKAEDLIKEGnNIKLLIVDSLTSHFRAEYVGRGTLAERQQKLNKHLHDLHRLADLYN 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1585497099 161 VAVVITNQVVSSVDgaaaMFNADPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAVFAITENGIAD 237
Cdd:cd19515 161 IAVLVTNQVMAKPD----AFFGDPTQAIGGHILGHAATFRVYLRKGKGGKRIARLVDSPHLPEGEAVFRITEKGIED 233
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
1-238 |
5.14e-117 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 336.85 E-value: 5.14e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 1 YLTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIAARYNL 80
Cdd:PRK04301 83 KITTGSKELDELLGGGIETQSITEFYGEFGSGKTQICHQLAVNVQLPEEKGGLEGKAVYIDTEGTFRPERIEQMAEALGL 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 81 DPEQVLENVSYARAYNSDHQsQLLIQAAAMMSESNYSV--LIVDSATALYRTDFSGRGELGARQIHLARFLRMLMRLADE 158
Cdd:PRK04301 163 DPDEVLDNIHVARAYNSDHQ-MLLAEKAEELIKEGENIklVIVDSLTAHFRAEYVGRGNLAERQQKLNKHLHDLLRLADL 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 159 FGVAVVITNQVVSSVDgaaaMFNADPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAVFAITENGIADP 238
Cdd:PRK04301 242 YNAAVVVTNQVMARPD----AFFGDPTQPIGGHILGHTATFRIYLRKSKGNKRIARLVDSPHLPEGEAVFRITEEGIRDA 317
|
|
| recomb_radA |
TIGR02236 |
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ... |
2-237 |
1.19e-105 |
|
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 131290 [Multi-domain] Cd Length: 310 Bit Score: 307.83 E-value: 1.19e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIAARYNLD 81
Cdd:TIGR02236 77 ITTGSKELDELLGGGIETQAITEVFGEFGSGKTQICHQLAVNVQLPEEKGGLGGKAVYIDTENTFRPERIMQMAEARGLD 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 82 PEQVLENVSYARAYNSDHQSQLLIQAAAMMSESNYSV--LIVDSATALYRTDFSGRGELGARQIHLARFLRMLMRLADEF 159
Cdd:TIGR02236 157 PDEVLKNIYVARAYNSNHQMLLVEKAEDLIKELNNPVklLIVDSLTSHFRAEYVGRGALAERQQKLNKHLHDLLRLADLY 236
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1585497099 160 GVAVVITNQVVSSVDgaaaMFNADPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAVFAITENGIAD 237
Cdd:TIGR02236 237 NAAVVVTNQVMARPD----AFFGDPTRPIGGHILGHAATFRVYLRKGKGDKRIARLVDSPHLPEGEAVFRITEKGIED 310
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
2-237 |
2.31e-52 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 168.89 E-value: 2.31e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCqlpTESGGssgKAMYIDTEGtFRSERLVSIAARynlD 81
Cdd:PRK09361 5 LPTGCKMLDELLGGGFERGTITQIYGPPGSGKTNICLQLAVEA---AKNGK---KVIYIDTEG-LSPERFKQIAGE---D 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 82 PEQVLENVSYARAYNSDHQSQLlIQAAAMMSESNYSVLIVDSATALYRTDFSGRGELGARQIHLARFLRMLMRLADEFGV 161
Cdd:PRK09361 75 FEELLSNIIIFEPSSFEEQSEA-IRKAEKLAKENVGLIVLDSATSLYRLELEDEEDNSKLNRELGRQLTHLLKLARKHDL 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1585497099 162 AVVITNQVVSSVDgaaamfnADPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAV-FAITENGIAD 237
Cdd:PRK09361 154 AVVITNQVYSDID-------SDGLRPLGGHTLEHWSKTILRLEKFRNGKRRATLEKHRSRPEGESAeFRITDRGIEI 223
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
20-205 |
2.08e-51 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 165.22 E-value: 2.08e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 20 GGITEIFGEFRTGKTQICHTIAVTCQLptesggSSGKAMYIDTEGTFRSERLVSIAARYN---LDPEQVLENVSYARAYN 96
Cdd:cd01393 1 GKITEIYGPPGSGKTQLALQLAANALL------LGGGVVWIDTEGAFPPSRLVQILEASPsseLELAEALSRLLYFRPPD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 97 SDHQSQLLIQAAAMMSES-NYSVLIVDSATALYRTDF----SGRGELGARQIHLARFLRMLMRLADEFGVAVVITNQVVS 171
Cdd:cd01393 75 TLAHLLALDSLPESLFPPpNTSLVVVDSVSALFRKAFprggDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQVTT 154
|
170 180 190
....*....|....*....|....*....|....
gi 1585497099 172 SVDGaaaMFNADPKKPVGGNIMAHASTTRLYLRK 205
Cdd:cd01393 155 KIRG---GSGASLVPPALGNTWEHSVSTRLLLYR 185
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
9-222 |
5.16e-49 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 161.31 E-value: 5.16e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 9 LDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIAARY-----NLDPE 83
Cdd:cd19491 1 LDELLGGGIPVGGITEIAGESGAGKTQLCLQLALTVQLPRELGGLGGGAVYICTESSFPSKRLQQLASSLpkryhLEKAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 84 QVLENVSYARAYNSDHQSQLLI-QAAAMMSESNYSVLIVDSATALYRTDF-SGRGELGARQIHLARFLRMLMRLADEFGV 161
Cdd:cd19491 81 NFLDNIFVEHVADLETLEHCLNyQLPALLERGPIRLVVIDSIAALFRSEFdTSRSDLVERAKYLRRLADHLKRLADKYNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 162 AVVITNQVVSSVD-----------GAAAMFNADPKKPVGGNIM-------AHASTTRLYLRKGKGET----------RIC 213
Cdd:cd19491 161 AVVVVNQVTDRFDsssdasglgvlDYLSQFSSFSGGVSGNRKVpalgltwANLVNTRLMLSRTPKRItdssaasisvRRL 240
|
....*....
gi 1585497099 214 KIYDSPCLP 222
Cdd:cd19491 241 EVVFSPHLP 249
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
2-235 |
3.01e-47 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 155.55 E-value: 3.01e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVtcqlptESGGSSGKAMYIDTEGtFRSERLVSIAARynlD 81
Cdd:cd01394 1 LSTGSKSLDSLLGGGVERGTITQIYGPPGSGKTNICLQLAV------EAAKQGKKVVYIDTEG-LSPERFQQIAGE---R 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 82 PEQVLENVSYARAYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRTDFSGRGELGARqihLARFLRMLMRLADEFGV 161
Cdd:cd01394 71 FESIASNIIVFEPYSFDEQGVAIQEAEKLLKSDKVDLVVVDSATALYRLELGDDSEANRE---LSRQMSKLLSIARKYDI 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1585497099 162 AVVITNQVVSSVDgaaamfnADPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAV-FAITENGI 235
Cdd:cd01394 148 PVVITNQVYSDID-------DDRLKPVGGTLLEHWSKAIIRLEKSPPGLRRATLEKHRSRPEGQSAgFRITDRGI 215
|
|
| recomb_radB |
TIGR02237 |
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ... |
9-235 |
7.03e-42 |
|
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).
Pssm-ID: 274047 [Multi-domain] Cd Length: 209 Bit Score: 141.78 E-value: 7.03e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 9 LDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTcqlpteSGGSSGKAMYIDTEGtFRSERLVSIAARynlDPEQVLEN 88
Cdd:TIGR02237 1 IDELLGGGVERGTITQIYGPPGSGKTNICMILAVN------AARQGKKVVYIDTEG-LSPERFKQIAED---RPERALSN 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 89 VSYARAYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRTDFSgrGELGARQIHLARFLRMLMRLADEFGVAVVITNQ 168
Cdd:TIGR02237 71 FIVFEVFDFDEQGVAIQKTSKFIDRDSASLVVVDSFTALYRLELS--DDRISRNRELARQLTLLLSLARKKNLAVVITNQ 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1585497099 169 VVSSVDGaaamfnaDPKKPVGGNIMAHASTTRLYLRKGKGETRICKIYDSPCLPESEAVFAITENGI 235
Cdd:TIGR02237 149 VYTDVNN-------GTLRPLGGHLLEHWSKVILRLEKFRGRRLATLEKHRSRPEGESVYFRITDDGI 208
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
10-219 |
9.84e-38 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 131.29 E-value: 9.84e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 10 DKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFRSERLVSIA-ARY---------- 78
Cdd:cd19493 1 DTALAGGLPLGAITEITGASGSGKTQFALTLASSAAMPARKGGLDGGVLYIDTESKFSAERLAEIAeARFpeafsgfmee 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 79 NLDPEQVLENVSYARAYNSDhqsQLLIQAAAM---MSESNYSVLIVDSATALYRTDFSG-RGELGARQIHLARFLRMLMR 154
Cdd:cd19493 81 NERAEEMLKRVAVVRVTTLA---QLLERLPNLeehILSSGVRLVVIDSIAALVRREFGGsDGEVTERHNALAREASSLKR 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1585497099 155 LADEFGVAVVITNQVVSSVDGAAAMFNADpkKPVGGNIMAHASTTRLYLRKGKG-ETRICKIYDSP 219
Cdd:cd19493 158 LAEEFRIAVLVTNQATTHFGDAGDGSSGV--TAALGDAWAHAVNTRLRLERCLLqLRRVLEIVKSP 221
|
|
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
20-219 |
3.32e-32 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 115.40 E-value: 3.32e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 20 GGITEIFGEFRTGKTQICHTIAVTCQLPTESGGSSGKAMYIDTEGTFrserlvsiaarynldpeqvleNVSYARAYNSDH 99
Cdd:cd19492 1 GKITEICGVPGVGKTQLCMQLAVNVQIPKCFGGLAGEAIYIDTEGSF---------------------NIHYFRVHDYVE 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 100 QSQLLIQAAAMMSE-SNYSVLIVDSATALYRTDFSGrgeLGARQIHLARFLRMLMRLADEFGVAVVITNQVVSSV--DGA 176
Cdd:cd19492 60 LLALINSLPKFLEDhPKVKLIVVDSIAFPFRHDFDD---LAQRTRLLNGLAQLLHSLARQHNLAVVLTNQVTTKIseDGQ 136
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1585497099 177 AAMFnadpkkPVGGNIMAHASTTRLYLRKgKGETRICKIYDSP 219
Cdd:cd19492 137 SQLV------PALGESWSHACTTRLFLTW-DEKQRFAHLYKSP 172
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
3-235 |
1.34e-27 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 107.95 E-value: 1.34e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 3 TTGSSELDKLLN-GGIESGGITEIFGEFRTGKTQICHTIAVTCQLpteSGGSsgkAMYIDTEGTFRSERlvsiAARYNLD 81
Cdd:COG0468 45 STGSLALDIALGvGGLPRGRIVEIYGPESSGKTTLALHAIAEAQK---AGGI---AAFIDAEHALDPEY----AKKLGVD 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 82 PEQVLenvsYARAYNSDHqsQLLIqAAAMMSESNYSVLIVDSATALYRtdfsgR----GELGARQIHL-ARF----LRML 152
Cdd:COG0468 115 IDNLL----VSQPDTGEQ--ALEI-AETLVRSGAVDLIVVDSVAALVP-----KaeieGEMGDSHVGLqARLmsqaLRKL 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 153 MRLADEFGVAVVITNQVVSSVDgaaAMFnADPKKPVGGNIMAHASTTRLYLRKG----KGETRI-----CKIYDSPCLPE 223
Cdd:COG0468 183 TGAISKSNTTVIFINQLREKIG---VMF-GNPETTTGGNALKFYASVRLDIRRIgtikDGDEVIgnrtrVKVVKNKVAPP 258
|
250
....*....|....
gi 1585497099 224 -SEAVFAIT-ENGI 235
Cdd:COG0468 259 fKEAEFDIMyGEGI 272
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
14-205 |
1.07e-26 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 102.33 E-value: 1.07e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 14 NGGIESGGITEIFGEFRTGKTQICHTIA--VTCQlptesggSSGKAMYIDTEGTFRSERLVSIA-ARYNL--DPEQVLEN 88
Cdd:cd19489 1 GGGLRTGEITELVGESSSGKTQLCLTAAanVASR-------SGQNVLYIDTKSSFSARRLAQILkSRAQDaeEIDKALQR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 89 VSYARAYNSDHQSQLLIQAAAMMS---ESNYS---VLIVDSATALYRTDFS------GRGELgarqIHLARFLRmlmRLA 156
Cdd:cd19489 74 IRVVRVFDPYELLDLLEELRNTLSqqqENLYSrlkLVIIDSLSALISPLLGgskhseGHALL----ASLARLLK---KLA 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1585497099 157 DEFGVAVVITNQVVSSVDGaaaMFNADPkKPVGGNIMAHASTTRLYLRK 205
Cdd:cd19489 147 AEYQIAVLVTNLTVRGGDG---GQQGST-KPALGEYWESVPSTRLLLSR 191
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
20-205 |
2.69e-18 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 80.47 E-value: 2.69e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 20 GGITEIFGEFRTGKTQICHTIAVTCQLPTES-----GGSSGKAMYIDTEGTFRSERLVSI----------AARYNLDPEQ 84
Cdd:cd19490 1 GDVIEITGPSGSGKTELLYHLAARCILPSSWggvplGGLEAAVVFIDTDGRFDILRLRSIleariraaiqAANSSDDEED 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 85 V-------LENVSYARAYNSDH-----QS--QLLIQAAAmmsESNYSVLIVDSATALYRTDFSGRGELGARQIHLARF-- 148
Cdd:cd19490 81 VeeiarecLQRLHIFRCHSSLQllatlLSleNYLLSLSA---NPELGLLLIDSISAFYWQDRFSAELARAAPLLQEAAlr 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1585497099 149 --LRMLMRLADEFGVAVVITNQVVSSVDGAAAMFNADPKKPVGGNIMAHAS----------TTRLYLRK 205
Cdd:cd19490 158 aiLRELRRLRRRFQLVVIATKQALFPGKSASTDNPAANNAVSKASAPSHREylprpwqrlvTHRLVLSR 226
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
2-235 |
1.63e-14 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 69.94 E-value: 1.63e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVtcqlpteSGGSSG-KAMYIDTEgtFRSERLVSIAARYNL 80
Cdd:COG0467 2 VPTGIPGLDELLGGGLPRGSSTLLSGPPGTGKTTLALQFLA-------EGLRRGeKGLYVSFE--ESPEQLLRRAESLGL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 81 DPEQVLEN-----VSYARAYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRtdfsgrgeLGARQIHLARFLRMLMRL 155
Cdd:COG0467 73 DLEEYIESgllriIDLSPEELGLDLEELLARLREAVEEFGAKRVVIDSLSGLLL--------ALPDPERLREFLHRLLRY 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 156 ADEFGVAVVITNQVVSSVDgaaamfnadpkkPVGGNIMAHASTTRLYLRK--GKGETR----ICKIYDSPClPESEAVFA 229
Cdd:COG0467 145 LKKRGVTTLLTSETGGLED------------EATEGGLSYLADGVILLRYveLGGELRralsVLKMRGSAH-DRTIREFE 211
|
....*.
gi 1585497099 230 ITENGI 235
Cdd:COG0467 212 ITDGGI 217
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
12-211 |
1.20e-11 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 63.00 E-value: 1.20e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 12 LLNGGIESGGITEIFGEFRTGKT----QICHTIAvtcqlpteSGGS-------SGKAMYIDTEGTFRS--ERLVSIAARY 78
Cdd:COG3598 5 LVPGLLPEGGVTLLAGPPGTGKSflalQLAAAVA--------AGGPwlgrrvpPGKVLYLAAEDDRGElrRRLKALGADL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 79 NLDPEQVLENVSYARAYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRTDfsgrgELGARQIhlARFLRMLMRLADE 158
Cdd:COG3598 77 GLPFADLDGRLRLLSLAGDLDDTDDLEALERAIEEEGPDLVVIDPLARVFGGD-----ENDAEEM--RAFLNPLDRLAER 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1585497099 159 FGVAVVI---TNQVVSSVDGAAAMFnadpkkpvGGNIMAHASTTRLYLRKGKGETR 211
Cdd:COG3598 150 TGAAVLLvhhTGKGGAGKDSGDRAR--------GSSALRGAARSVLVLSREKGEDL 197
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
4-206 |
1.37e-09 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 56.41 E-value: 1.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 4 TGSSELDKLLN-GGIESGGITEIFGEFRTGKTQIC-HTIAvtcqlptESGGSSGKAMYIDTEGTfrserlvsiaarynLD 81
Cdd:cd00983 7 TGSLSLDIALGiGGLPRGRIIEIYGPESSGKTTLAlHAIA-------EAQKLGGTAAFIDAEHA--------------LD 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 82 PEqvlenvsYARAYNSDHQSQLLIQ------AAAMMSE---SN-YSVLIVDSATALY-RTDFSgrGELGARQIHL-AR-- 147
Cdd:cd00983 66 PE-------YAKKLGVDIDNLLVSQpdtgeqALEIADTlirSGaVDLIVVDSVAALVpKAEIE--GEMGDSHVGLqARlm 136
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1585497099 148 --FLRMLMRLADEFGVAVVITNQVVSSVdgaAAMFNAdPKKPVGGNIMAHASTTRLYLRKG 206
Cdd:cd00983 137 sqALRKLTGSLSKSKTTVIFINQLREKI---GVMFGN-PETTTGGNALKFYASVRLDIRRI 193
|
|
| RecA |
pfam00154 |
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ... |
2-205 |
2.50e-09 |
|
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.
Pssm-ID: 425488 [Multi-domain] Cd Length: 262 Bit Score: 55.87 E-value: 2.50e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLN-GGIESGGITEIFGEFRTGKTQIC-HTIAvtcqlptESGGSSGKAMYIDTEgtfrserlvsiaarYN 79
Cdd:pfam00154 33 ISTGSLALDIALGiGGYPKGRIIEIYGPESSGKTTLAlHAIA-------EAQKAGGTAAFIDAE--------------HA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 80 LDPeqvlenvSYARAYNSDHQSQLLIQA---------AAMMSESN-YSVLIVDSATALY-RTDFSgrGELGARQIHL-AR 147
Cdd:pfam00154 92 LDP-------VYAKKLGVDIDNLLVSQPdtgeqaleiADMLVRSGaIDLIVVDSVAALVpKAEIE--GEMGDSHVGLqAR 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1585497099 148 F----LRMLMRLADEFGVAVVITNQVVSSVdgaAAMFnADPKKPVGGNIMAHASTTRLYLRK 205
Cdd:pfam00154 163 LmsqaLRKLTGSISKSNTTVIFINQIREKI---GVMF-GNPETTTGGRALKFYASVRLDIRR 220
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
19-183 |
6.41e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 53.15 E-value: 6.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 19 SGGITEIFGEFRTGKTQICHTIAVtcqlptESGGSSGKAMYIDTEGTFRSERlvsiaarynldpeQVLENVSYARAYNSD 98
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALAR------ELGPPGGGVIYIDGEDILEEVL-------------DQLLLIIVGGKKASG 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 99 HQSQLLIQAAAMMSESNYSVLIVDSATALYRTDFSgrgelgaRQIHLARFLRMLMRLADEFGVAVVITNQVVSSVDGAAA 178
Cdd:smart00382 62 SGELRLRLALALARKLKPDVLILDEITSLLDAEQE-------ALLLLLEELRLLLLLKSEKNLTVILTTNDEKDLGPALL 134
|
....*
gi 1585497099 179 MFNAD 183
Cdd:smart00382 135 RRRFD 139
|
|
| PRK06067 |
PRK06067 |
flagellar accessory protein FlaH; Validated |
2-166 |
1.36e-06 |
|
flagellar accessory protein FlaH; Validated
Pssm-ID: 180381 Cd Length: 234 Bit Score: 47.66 E-value: 1.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTqichtiaVTCQLPTESGGSSGKAM-YIDTEGTFRSERLVSIAARYNL 80
Cdd:PRK06067 7 ISTGNEELDRKLGGGIPFPSLILIEGDHGTGKS-------VLSQQFVYGALKQGKKVyVITTENTSKSYLKQMESVKIDI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 81 DPE------QVLE-NVSYARaYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALyrtdfsgrgELGARQIHLARFLRMLM 153
Cdd:PRK06067 80 SDFflwgylRIFPlNTEGFE-WNSTLANKLLELIIEFIKSKREDVIIIDSLTIF---------ATYAEEDDILNFLTEAK 149
|
170
....*....|...
gi 1585497099 154 RLADEfGVAVVIT 166
Cdd:PRK06067 150 NLVDL-GKTILIT 161
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
8-166 |
5.31e-06 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 45.45 E-value: 5.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 8 ELDKLLNGGIESGGITEIFGEFRTGKT----QICHTIAVTCQLP-TESGGSSGKAMYIDTEGTFRSERLVSIAARYNLDP 82
Cdd:pfam13481 21 PRRWLIKGLLPAGGLGLLAGAPGTGKTtlalDLAAAVATGKPWLgGPRVPEQGKVLYVSAEGPADELRRRLRAAGADLDL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 83 EQVLENVSYA---RAYNSDHQSQLLIQAAAMMSES-----NYSVLIVDSATALYRTDFSGRGELGarqihlaRFLRMLMR 154
Cdd:pfam13481 101 PARLLFLSLVeslPLFFLDRGGPLLDADVDALEAAleeveDPDLVVIDPLARALGGDENSNSDVG-------RLVKALDR 173
|
170
....*....|..
gi 1585497099 155 LADEFGVAVVIT 166
Cdd:pfam13481 174 LARRTGATVLLV 185
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
2-169 |
5.98e-05 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 42.90 E-value: 5.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKT----QICHTIAvtcqlptesgGSSGKAMYIDTEGT-----FRSERLV 72
Cdd:cd01121 64 ISTGIGELDRVLGGGLVPGSVVLIGGDPGIGKStlllQVAARLA----------QRGGKVLYVSGEESlsqikLRAERLG 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 73 SIAARYNLDPEQVLENVsyaraynsdhqsqlliqaAAMMSESNYSVLIVDSATALYRTDFSGR-GelGARQIhlarflR- 150
Cdd:cd01121 134 LGSDNLYLLAETNLEAI------------------LAEIEELKPSLVVIDSIQTVYSPELTSSpG--SVSQV------Re 187
|
170 180
....*....|....*....|..
gi 1585497099 151 ---MLMRLADEFGVAVVITNQV 169
Cdd:cd01121 188 caaELLRLAKETGIPVFLVGHV 209
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
2-235 |
8.85e-05 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 42.25 E-value: 8.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTcQLPTEsggssGKAMYIDTEGTfrSERLVSIAAR--YN 79
Cdd:cd01124 1 VKTGIPGLDELLGGGIPKGSVTLLTGGPGTGKTLFGLQFLYA-GAKNG-----EPGLFFTFEES--PERLLRNAKSfgWD 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 80 LDPEQVLENVSYARAYNSDHQSQLLIQAAAMMSES----NYSVLIVDSATALYRtdfsgrgelgaRQIHLARFLRMLMRL 155
Cdd:cd01124 73 FDEMEDEGKLIIVDAPPTEAGRFSLDELLSRILSIiksfKAKRVVIDSLSGLRR-----------AKEDQMRARRIVIAL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 156 ADEF---GVAVVITNQVVSSVDGAAAMFnADPKKPVGGNImahasttRLYLRKGKGETR----ICKIYDSPcLPESEAVF 228
Cdd:cd01124 142 LNELraaGVTTIFTSEMRSFLSSESAGG-GDVSFIVDGVI-------LLRYVEIEGELRrtirVLKMRGTG-HDTGTHPF 212
|
....*..
gi 1585497099 229 AITENGI 235
Cdd:cd01124 213 EITDKGI 219
|
|
| ATPase |
pfam06745 |
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ... |
4-235 |
2.17e-04 |
|
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.
Pssm-ID: 429095 [Multi-domain] Cd Length: 231 Bit Score: 41.08 E-value: 2.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 4 TGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVT-CQLPTESGgssgkaMYIDTEgtfrsERLVSI---AARYN 79
Cdd:pfam06745 3 TGIPGLDEILKGGFPEGRVVLITGGPGTGKTIFGLQFLYNgALKYGEPG------VFVTLE-----EPPEDLrenARSFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 80 LDPEQVLEN------------VSYARAYNSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRTDFSGRgelgARQIhlar 147
Cdd:pfam06745 72 WDLEKLEEEgklaiidastsgIGIAEVEDRFDLEELIERLREAIREIGAKRVVIDSITTLFYLLKPAV----AREI---- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 148 FLRMLMRLAdEFGVAVVITNQVVSSVDGAaamfnadpkkpvGGNIMAHAS---TTRLYLRKGKGET----RICKIYDSPc 220
Cdd:pfam06745 144 LRRLKRVLK-GLGVTAIFTSEKPSGEGGI------------GGYGVEEFIvdgVIRLDLKEIEEERvrtiEIVKMRGTP- 209
|
250
....*....|....*
gi 1585497099 221 LPESEAVFAITENGI 235
Cdd:pfam06745 210 HSMKRYPFEITDNGI 224
|
|
| FlaH |
COG2874 |
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility]; |
1-166 |
1.80e-03 |
|
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility];
Pssm-ID: 442121 Cd Length: 230 Bit Score: 38.27 E-value: 1.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 1 YLTTGSSELDKLLNGGIESGGITEIFGEFRTGKTqichtiaVTCQLPTESGGSSG-KAMYIDTEGTFRSERLVSIAARYN 79
Cdd:COG2874 2 IISTGNDELDKRLGGGIPLGSLVLIEGENGTGKS-------VLSQQFAYGALENGlSVTYISTELTTKEFIKQMKSLSYD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 80 LDPEQVLENVSYARAY------NSDHQSQLLIQAAAMMSE--SNYSVLIVDSATALYRtdfsgrgelGARQIHLARFLRM 151
Cdd:COG2874 75 ISDYLLRGRLLFLPVHplgfewNSKQRKDLLKRLMKYIASnlWEADVIIIDSLSALLR---------NAEESAILDFITF 145
|
170
....*....|....*
gi 1585497099 152 LMRLADEfGVAVVIT 166
Cdd:COG2874 146 FKNLVDL-GKTIILT 159
|
|
| recA |
PRK09354 |
recombinase A; Provisional |
4-127 |
2.75e-03 |
|
recombinase A; Provisional
Pssm-ID: 236476 [Multi-domain] Cd Length: 349 Bit Score: 38.24 E-value: 2.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 4 TGSSELDKLLN-GGIESGGITEIFGEFRTGKTQIC-HTIAvTCQlptESGGSsgkAMYIDTEGTfrserlvsiaarynLD 81
Cdd:PRK09354 43 TGSLALDIALGiGGLPRGRIVEIYGPESSGKTTLAlHAIA-EAQ---KAGGT---AAFIDAEHA--------------LD 101
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1585497099 82 PeqvlenvSYARAYNSDHQSqLLI-------QA---AAMMSESN-YSVLIVDSATAL 127
Cdd:PRK09354 102 P-------VYAKKLGVDIDN-LLVsqpdtgeQAleiADTLVRSGaVDLIVVDSVAAL 150
|
|
| KaiC-like_C |
cd19487 |
C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ... |
2-36 |
3.06e-03 |
|
C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410895 [Multi-domain] Cd Length: 219 Bit Score: 37.66 E-value: 3.06e-03
10 20 30
....*....|....*....|....*....|....*
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQI 36
Cdd:cd19487 1 VSSGVPELDELLGGGLERGTSTLLIGPAGVGKSTL 35
|
|
| FlaH |
cd19475 |
flagellar accessory protein FlaH; Flagellar accessory protein FlaH is part of the motor of the ... |
2-191 |
3.17e-03 |
|
flagellar accessory protein FlaH; Flagellar accessory protein FlaH is part of the motor of the archaellum membrane-anchored archaeal motility structure, together with FlaX and FlaI. FlaH forms a hexameric ring, and binds ATP which is essential for its interaction with FlaI and for archaellum assembly.
Pssm-ID: 410883 Cd Length: 220 Bit Score: 37.58 E-value: 3.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 2 LTTGSSELDKLLNGGIESGGITEIFGEFRTGKTQICHTIAVTCQLptesggSSGKAMYIDTEGTFRSERLVSIAARYNLD 81
Cdd:cd19475 1 ISLGRDDLDKRLGGGIPYPSSIMIEGEESTGKSVLSQRLVYGFLQ------NDYSGYYISTQQTTKEFLKQMKSLKYDIN 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585497099 82 PEQVLENVSYARAY----NSDHQSQLLIQAAAMMSESNYSVLIVDSATALYRTDfsgrgelgARQIHLARFLRMLMRLAD 157
Cdd:cd19475 75 KKLLRGKLLYIPVYplifDNSLKDKFLKKIVNTRAFYEKDFIIFDSLSILIAND--------ASEVQVLDLMKFIKRIVN 146
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1585497099 158 EFGVAVVITN------QVVSSVDGAAAMFNADPKKPVGGN 191
Cdd:cd19475 147 TGKIILFTINpkeldeEVKTKIRTIATVYIKTEAFTFGGR 186
|
|
| PRK08533 |
PRK08533 |
flagellar accessory protein FlaH; Reviewed |
8-48 |
6.97e-03 |
|
flagellar accessory protein FlaH; Reviewed
Pssm-ID: 181459 Cd Length: 230 Bit Score: 36.59 E-value: 6.97e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1585497099 8 ELDKLLNGGIESGGITEIFGEFRTGKTQICHTIA------------VTCQLPT 48
Cdd:PRK08533 12 ELHKRLGGGIPAGSLILIEGDESTGKSILSQRLAygflqngysvsyVSTQLTT 64
|
|
| |
