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Conserved domains on  [gi|2129099152|gb|UEE94667|]
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structural polyprotein [Sindbis virus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Alpha_E2_glycop super family cl03027
Alphavirus E2 glycoprotein; E2 forms a heterodimer with E1. The virus spikes are made up of 80 ...
341-747 0e+00

Alphavirus E2 glycoprotein; E2 forms a heterodimer with E1. The virus spikes are made up of 80 trimers of these heterodimers (sindbis virus).


The actual alignment was detected with superfamily member pfam00943:

Pssm-ID: 425959  Cd Length: 403  Bit Score: 664.33  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  341 PYLGTCPYCHHTEPCFSPIKIEQVWDEADDNTIRIQTSAQFGYDQSGAASVNKYRIMslkQDHTVEEGSMDAIKISTSGP 420
Cdd:pfam00943    1 PYLAHCPDCGEGHSCHSPVAIERVRNEATDGTLKIQVSAQIGIDTSDSHDWTKLRYM---DNHIPADAGRAGLKVRTSGP 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  421 CRRLSHKGYFLLAKCPPGDSVTVSISAGDSAT-SCTLARKIKPKFVGREKYDLPPVHGKKIPCYIYDRLKETSAGYITMH 499
Cdd:pfam00943   78 CTITGTMGHFILAKCPPGETLTVSITDSRKAShSCTHPFHHDPPVVGREKFHSRPQHGKEIPCTTYVQSNAATAEEIEMH 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  500 RPGPHAYTTYLEESSGKVYAKPpSGKNVTYECKCGDYKTDTVSARTEITGCtALKQCIAYRSDQTKWVFNSPDLIRHADH 579
Cdd:pfam00943  158 MPPDTPDRTLLSQQSGNVKITV-NGKTVRYKCNCGGSNEGTITTDKVINNC-KIDQCHAAVTDHKKWQFNSPLVPRNDEL 235
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  580 TAQGKMHLPFKLVPSTCLVPLAHVPQVVHGFKHISLQLDTDHLTLLTTRRLGEKPEPTSEWIIGKTVRNFSVGRDGFEYI 659
Cdd:pfam00943  236 GRKGKIHIPFPLANVTCMVPKARNPTVIHGKNQVILLLYPDHPTLLSYRSLGEEPNYQEEWVTHKKERVLTVPTDGLEYT 315
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  660 WGNHEPVRVWAQESAPGDPHGWPHEIVQHYYHRHPVYTVMVLVAATLAIVLGVSVASACVCRARRECLTPYALAPNAVVP 739
Cdd:pfam00943  316 WGNNEPVRYWPQLSANGTPHGWPHEIVQYYYELYPTMTVVAVSVASFILLIMVGMAVGMCMCARRRCLTPYALTPGATVP 395

                   ....*...
gi 2129099152  740 TSIALLCC 747
Cdd:pfam00943  396 FLLSLLCC 403
Alpha_E1_glycop super family cl03274
Alphavirus E1 glycoprotein; E1 forms a heterodimer with E2 pfam00943. The virus spikes are ...
749-1247 0e+00

Alphavirus E1 glycoprotein; E1 forms a heterodimer with E2 pfam00943. The virus spikes are made up of 80 trimers of these heterodimers (sindbis virus).


The actual alignment was detected with superfamily member pfam01589:

Pssm-ID: 279870  Cd Length: 504  Bit Score: 605.11  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  749 RPTSAEPFSETMTYLWTNSQPFFWAQLCIPLAAIIVL------VRCCSCCLPFLVVAGAYLAKVDAFEHATTVPNVPRIP 822
Cdd:pfam01589    1 PRAHAASVAEAAAYLWDENQALFWLEAAAPLAAIIIIcnclrlLLCCCKSLAFLALLSIGAATARAYEHSTVIPNTVGFP 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  823 YKALVERAGYAPLNLEITVMSSELIPSTNLEYVTCKYTTVVPSPKVKCCGTLECSSARHADYNCKVFGGVYPFMWGGALC 902
Cdd:pfam01589   81 YKAHIERPGYSPLTLEMELLETSLEPTLNLDYITCEYKTVIPSPYVKCCGAAECKDKEKPDYQCKVFTGVYPFMWGGAYC 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  903 FCDSENSQMSEAYVEFSADCAADHAQAVKVHTAALKVGLRVVYGNTTSMLDVYVNGVTPGTSKDLKVIAGPISAAYTPFD 982
Cdd:pfam01589  161 FCDAENTQLSEAHVDKSDSCKHDFASAYKAHTASAKAKLRVLYGGNNITVDAYANGDHAVTIGDAKFIFGPLSSAWTPFD 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  983 HKVIIHKGKVYNYDFPEYGAMKPGAFGDIQATSLTSSDLIANTDIRLLKPSAKNVHVPYTQAASGFEMWKNNSGRPLQET 1062
Cdd:pfam01589  241 NKIVVYKDDVFNMDFPPFGAGQPGQFGDIQSRTPESKDLYANTALKLARPAAGMVHVPYSQAPSGFKYWLKEKGAALNHK 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152 1063 APFGCQIAVNPLRAIDCAYGNIPISLDIPNAAFIRVSDAPLVSTLKCEVGECVYSADFGGIATLQYSSDREGQCPVHSHS 1142
Cdd:pfam01589  321 APFGCQIATNPVRAMNCAVGNIPISIDIPDAAFTRIVDAPSIIDLSCEVAACTHSSDFGGVAIIKYATNKKGDCAVHSHS 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152 1143 STATLQESTVHVLQKGGVTIHFSTASPQANFIVSLCGKKTTCNAECKPPADHIVNVPHKNDQEFQAAVSQTSWSWLFALF 1222
Cdd:pfam01589  401 NAATIQEAEAEVEGAGKLQIHFSTALASAEFRVQLCSAQAHCAAECEPPKDHIVNYAASHSNLGFPDISATALSWVQKIS 480
                          490       500
                   ....*....|....*....|....*
gi 2129099152 1223 GGAsSLLVIGVMIFACSALLTSTRR 1247
Cdd:pfam01589  481 GGL-GAFAAGAALILIVVLCIGFRR 504
Peptidase_S3 super family cl03028
Alphavirus core protein; Also known as coat protein C and capsid protein C. This makes the ...
109-266 3.73e-98

Alphavirus core protein; Also known as coat protein C and capsid protein C. This makes the literature very confusing. Alphaviruses consist of a nucleoprotein core, a lipid membrane which envelopes the core, and glycoprotein spikes protruding from the lipid membrane.


The actual alignment was detected with superfamily member pfam00944:

Pssm-ID: 366379  Cd Length: 156  Bit Score: 309.23  E-value: 3.73e-98
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  109 ALKLEADRLFDVKNEaGEVIGHALAMEGKVMKPLHVKGTIDHPVLSKLKFTKSSAYDMEFAQLPTNMRSEAFSYTSEHPE 188
Cdd:pfam00944    1 CMKIENDCIFEVKHE-GKVTGYACLVGDKVMKPAHVKGTIDNADLAKLAFKKSSKYDLECAQIPVHMRSDASKYTHEKPE 79
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2129099152  189 GFYNWHHGAVQYSGGRFTVPKGAGGKGDSGRPIMDNTGKVVAIVLGGADEGARTALSVVTWNsKGKTIKTTPEGTEEW 266
Cdd:pfam00944   80 GFYNWHHGAVQYSGGRFTIPTGAGKPGDSGRPIFDNKGRVVAIVLGGANEGTRTALSVVTWN-KDKVTKTTPEGTEEW 156
PRK11633 super family cl25866
cell division protein DedD; Provisional
56-102 5.56e-04

cell division protein DedD; Provisional


The actual alignment was detected with superfamily member PRK11633:

Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 43.07  E-value: 5.56e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 2129099152   56 QVSRQQQPRQRPAPKPRRQPPKQQQPKSKKTKNPE-KPKQKQPTKSKP 102
Cdd:PRK11633    96 PVEPEPAPVEPPKPKPVEKPKPKPKPQQKVEAPPApKPEPKPVVEEKA 143
 
Name Accession Description Interval E-value
Alpha_E2_glycop pfam00943
Alphavirus E2 glycoprotein; E2 forms a heterodimer with E1. The virus spikes are made up of 80 ...
341-747 0e+00

Alphavirus E2 glycoprotein; E2 forms a heterodimer with E1. The virus spikes are made up of 80 trimers of these heterodimers (sindbis virus).


Pssm-ID: 425959  Cd Length: 403  Bit Score: 664.33  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  341 PYLGTCPYCHHTEPCFSPIKIEQVWDEADDNTIRIQTSAQFGYDQSGAASVNKYRIMslkQDHTVEEGSMDAIKISTSGP 420
Cdd:pfam00943    1 PYLAHCPDCGEGHSCHSPVAIERVRNEATDGTLKIQVSAQIGIDTSDSHDWTKLRYM---DNHIPADAGRAGLKVRTSGP 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  421 CRRLSHKGYFLLAKCPPGDSVTVSISAGDSAT-SCTLARKIKPKFVGREKYDLPPVHGKKIPCYIYDRLKETSAGYITMH 499
Cdd:pfam00943   78 CTITGTMGHFILAKCPPGETLTVSITDSRKAShSCTHPFHHDPPVVGREKFHSRPQHGKEIPCTTYVQSNAATAEEIEMH 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  500 RPGPHAYTTYLEESSGKVYAKPpSGKNVTYECKCGDYKTDTVSARTEITGCtALKQCIAYRSDQTKWVFNSPDLIRHADH 579
Cdd:pfam00943  158 MPPDTPDRTLLSQQSGNVKITV-NGKTVRYKCNCGGSNEGTITTDKVINNC-KIDQCHAAVTDHKKWQFNSPLVPRNDEL 235
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  580 TAQGKMHLPFKLVPSTCLVPLAHVPQVVHGFKHISLQLDTDHLTLLTTRRLGEKPEPTSEWIIGKTVRNFSVGRDGFEYI 659
Cdd:pfam00943  236 GRKGKIHIPFPLANVTCMVPKARNPTVIHGKNQVILLLYPDHPTLLSYRSLGEEPNYQEEWVTHKKERVLTVPTDGLEYT 315
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  660 WGNHEPVRVWAQESAPGDPHGWPHEIVQHYYHRHPVYTVMVLVAATLAIVLGVSVASACVCRARRECLTPYALAPNAVVP 739
Cdd:pfam00943  316 WGNNEPVRYWPQLSANGTPHGWPHEIVQYYYELYPTMTVVAVSVASFILLIMVGMAVGMCMCARRRCLTPYALTPGATVP 395

                   ....*...
gi 2129099152  740 TSIALLCC 747
Cdd:pfam00943  396 FLLSLLCC 403
Alpha_E1_glycop pfam01589
Alphavirus E1 glycoprotein; E1 forms a heterodimer with E2 pfam00943. The virus spikes are ...
749-1247 0e+00

Alphavirus E1 glycoprotein; E1 forms a heterodimer with E2 pfam00943. The virus spikes are made up of 80 trimers of these heterodimers (sindbis virus).


Pssm-ID: 279870  Cd Length: 504  Bit Score: 605.11  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  749 RPTSAEPFSETMTYLWTNSQPFFWAQLCIPLAAIIVL------VRCCSCCLPFLVVAGAYLAKVDAFEHATTVPNVPRIP 822
Cdd:pfam01589    1 PRAHAASVAEAAAYLWDENQALFWLEAAAPLAAIIIIcnclrlLLCCCKSLAFLALLSIGAATARAYEHSTVIPNTVGFP 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  823 YKALVERAGYAPLNLEITVMSSELIPSTNLEYVTCKYTTVVPSPKVKCCGTLECSSARHADYNCKVFGGVYPFMWGGALC 902
Cdd:pfam01589   81 YKAHIERPGYSPLTLEMELLETSLEPTLNLDYITCEYKTVIPSPYVKCCGAAECKDKEKPDYQCKVFTGVYPFMWGGAYC 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  903 FCDSENSQMSEAYVEFSADCAADHAQAVKVHTAALKVGLRVVYGNTTSMLDVYVNGVTPGTSKDLKVIAGPISAAYTPFD 982
Cdd:pfam01589  161 FCDAENTQLSEAHVDKSDSCKHDFASAYKAHTASAKAKLRVLYGGNNITVDAYANGDHAVTIGDAKFIFGPLSSAWTPFD 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  983 HKVIIHKGKVYNYDFPEYGAMKPGAFGDIQATSLTSSDLIANTDIRLLKPSAKNVHVPYTQAASGFEMWKNNSGRPLQET 1062
Cdd:pfam01589  241 NKIVVYKDDVFNMDFPPFGAGQPGQFGDIQSRTPESKDLYANTALKLARPAAGMVHVPYSQAPSGFKYWLKEKGAALNHK 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152 1063 APFGCQIAVNPLRAIDCAYGNIPISLDIPNAAFIRVSDAPLVSTLKCEVGECVYSADFGGIATLQYSSDREGQCPVHSHS 1142
Cdd:pfam01589  321 APFGCQIATNPVRAMNCAVGNIPISIDIPDAAFTRIVDAPSIIDLSCEVAACTHSSDFGGVAIIKYATNKKGDCAVHSHS 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152 1143 STATLQESTVHVLQKGGVTIHFSTASPQANFIVSLCGKKTTCNAECKPPADHIVNVPHKNDQEFQAAVSQTSWSWLFALF 1222
Cdd:pfam01589  401 NAATIQEAEAEVEGAGKLQIHFSTALASAEFRVQLCSAQAHCAAECEPPKDHIVNYAASHSNLGFPDISATALSWVQKIS 480
                          490       500
                   ....*....|....*....|....*
gi 2129099152 1223 GGAsSLLVIGVMIFACSALLTSTRR 1247
Cdd:pfam01589  481 GGL-GAFAAGAALILIVVLCIGFRR 504
Peptidase_S3 pfam00944
Alphavirus core protein; Also known as coat protein C and capsid protein C. This makes the ...
109-266 3.73e-98

Alphavirus core protein; Also known as coat protein C and capsid protein C. This makes the literature very confusing. Alphaviruses consist of a nucleoprotein core, a lipid membrane which envelopes the core, and glycoprotein spikes protruding from the lipid membrane.


Pssm-ID: 366379  Cd Length: 156  Bit Score: 309.23  E-value: 3.73e-98
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  109 ALKLEADRLFDVKNEaGEVIGHALAMEGKVMKPLHVKGTIDHPVLSKLKFTKSSAYDMEFAQLPTNMRSEAFSYTSEHPE 188
Cdd:pfam00944    1 CMKIENDCIFEVKHE-GKVTGYACLVGDKVMKPAHVKGTIDNADLAKLAFKKSSKYDLECAQIPVHMRSDASKYTHEKPE 79
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2129099152  189 GFYNWHHGAVQYSGGRFTVPKGAGGKGDSGRPIMDNTGKVVAIVLGGADEGARTALSVVTWNsKGKTIKTTPEGTEEW 266
Cdd:pfam00944   80 GFYNWHHGAVQYSGGRFTIPTGAGKPGDSGRPIFDNKGRVVAIVLGGANEGTRTALSVVTWN-KDKVTKTTPEGTEEW 156
PRK11633 PRK11633
cell division protein DedD; Provisional
56-102 5.56e-04

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 43.07  E-value: 5.56e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 2129099152   56 QVSRQQQPRQRPAPKPRRQPPKQQQPKSKKTKNPE-KPKQKQPTKSKP 102
Cdd:PRK11633    96 PVEPEPAPVEPPKPKPVEKPKPKPKPQQKVEAPPApKPEPKPVVEEKA 143
PRK01297 PRK01297
ATP-dependent RNA helicase RhlB; Provisional
59-146 1.44e-03

ATP-dependent RNA helicase RhlB; Provisional


Pssm-ID: 234938 [Multi-domain]  Cd Length: 475  Bit Score: 42.59  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152   59 RQQQPRQRPAPKPRRQPPKQQQPKSKKTKN-PEKPKQKQPTKSKPgKRQRMALKLEADRL--FDVKNEAGEVIGHALAME 135
Cdd:PRK01297    17 PAPAPPSPAAAPAPPPPAKTAAPATKAAAPaAAAPRAEKPKKDKP-RRERKPKPASLWKLedFVVEPQEGKTRFHDFNLA 95
                           90
                   ....*....|.
gi 2129099152  136 GKVMKPLHVKG 146
Cdd:PRK01297    96 PELMHAIHDLG 106
 
Name Accession Description Interval E-value
Alpha_E2_glycop pfam00943
Alphavirus E2 glycoprotein; E2 forms a heterodimer with E1. The virus spikes are made up of 80 ...
341-747 0e+00

Alphavirus E2 glycoprotein; E2 forms a heterodimer with E1. The virus spikes are made up of 80 trimers of these heterodimers (sindbis virus).


Pssm-ID: 425959  Cd Length: 403  Bit Score: 664.33  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  341 PYLGTCPYCHHTEPCFSPIKIEQVWDEADDNTIRIQTSAQFGYDQSGAASVNKYRIMslkQDHTVEEGSMDAIKISTSGP 420
Cdd:pfam00943    1 PYLAHCPDCGEGHSCHSPVAIERVRNEATDGTLKIQVSAQIGIDTSDSHDWTKLRYM---DNHIPADAGRAGLKVRTSGP 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  421 CRRLSHKGYFLLAKCPPGDSVTVSISAGDSAT-SCTLARKIKPKFVGREKYDLPPVHGKKIPCYIYDRLKETSAGYITMH 499
Cdd:pfam00943   78 CTITGTMGHFILAKCPPGETLTVSITDSRKAShSCTHPFHHDPPVVGREKFHSRPQHGKEIPCTTYVQSNAATAEEIEMH 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  500 RPGPHAYTTYLEESSGKVYAKPpSGKNVTYECKCGDYKTDTVSARTEITGCtALKQCIAYRSDQTKWVFNSPDLIRHADH 579
Cdd:pfam00943  158 MPPDTPDRTLLSQQSGNVKITV-NGKTVRYKCNCGGSNEGTITTDKVINNC-KIDQCHAAVTDHKKWQFNSPLVPRNDEL 235
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  580 TAQGKMHLPFKLVPSTCLVPLAHVPQVVHGFKHISLQLDTDHLTLLTTRRLGEKPEPTSEWIIGKTVRNFSVGRDGFEYI 659
Cdd:pfam00943  236 GRKGKIHIPFPLANVTCMVPKARNPTVIHGKNQVILLLYPDHPTLLSYRSLGEEPNYQEEWVTHKKERVLTVPTDGLEYT 315
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  660 WGNHEPVRVWAQESAPGDPHGWPHEIVQHYYHRHPVYTVMVLVAATLAIVLGVSVASACVCRARRECLTPYALAPNAVVP 739
Cdd:pfam00943  316 WGNNEPVRYWPQLSANGTPHGWPHEIVQYYYELYPTMTVVAVSVASFILLIMVGMAVGMCMCARRRCLTPYALTPGATVP 395

                   ....*...
gi 2129099152  740 TSIALLCC 747
Cdd:pfam00943  396 FLLSLLCC 403
Alpha_E1_glycop pfam01589
Alphavirus E1 glycoprotein; E1 forms a heterodimer with E2 pfam00943. The virus spikes are ...
749-1247 0e+00

Alphavirus E1 glycoprotein; E1 forms a heterodimer with E2 pfam00943. The virus spikes are made up of 80 trimers of these heterodimers (sindbis virus).


Pssm-ID: 279870  Cd Length: 504  Bit Score: 605.11  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  749 RPTSAEPFSETMTYLWTNSQPFFWAQLCIPLAAIIVL------VRCCSCCLPFLVVAGAYLAKVDAFEHATTVPNVPRIP 822
Cdd:pfam01589    1 PRAHAASVAEAAAYLWDENQALFWLEAAAPLAAIIIIcnclrlLLCCCKSLAFLALLSIGAATARAYEHSTVIPNTVGFP 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  823 YKALVERAGYAPLNLEITVMSSELIPSTNLEYVTCKYTTVVPSPKVKCCGTLECSSARHADYNCKVFGGVYPFMWGGALC 902
Cdd:pfam01589   81 YKAHIERPGYSPLTLEMELLETSLEPTLNLDYITCEYKTVIPSPYVKCCGAAECKDKEKPDYQCKVFTGVYPFMWGGAYC 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  903 FCDSENSQMSEAYVEFSADCAADHAQAVKVHTAALKVGLRVVYGNTTSMLDVYVNGVTPGTSKDLKVIAGPISAAYTPFD 982
Cdd:pfam01589  161 FCDAENTQLSEAHVDKSDSCKHDFASAYKAHTASAKAKLRVLYGGNNITVDAYANGDHAVTIGDAKFIFGPLSSAWTPFD 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  983 HKVIIHKGKVYNYDFPEYGAMKPGAFGDIQATSLTSSDLIANTDIRLLKPSAKNVHVPYTQAASGFEMWKNNSGRPLQET 1062
Cdd:pfam01589  241 NKIVVYKDDVFNMDFPPFGAGQPGQFGDIQSRTPESKDLYANTALKLARPAAGMVHVPYSQAPSGFKYWLKEKGAALNHK 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152 1063 APFGCQIAVNPLRAIDCAYGNIPISLDIPNAAFIRVSDAPLVSTLKCEVGECVYSADFGGIATLQYSSDREGQCPVHSHS 1142
Cdd:pfam01589  321 APFGCQIATNPVRAMNCAVGNIPISIDIPDAAFTRIVDAPSIIDLSCEVAACTHSSDFGGVAIIKYATNKKGDCAVHSHS 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152 1143 STATLQESTVHVLQKGGVTIHFSTASPQANFIVSLCGKKTTCNAECKPPADHIVNVPHKNDQEFQAAVSQTSWSWLFALF 1222
Cdd:pfam01589  401 NAATIQEAEAEVEGAGKLQIHFSTALASAEFRVQLCSAQAHCAAECEPPKDHIVNYAASHSNLGFPDISATALSWVQKIS 480
                          490       500
                   ....*....|....*....|....*
gi 2129099152 1223 GGAsSLLVIGVMIFACSALLTSTRR 1247
Cdd:pfam01589  481 GGL-GAFAAGAALILIVVLCIGFRR 504
Peptidase_S3 pfam00944
Alphavirus core protein; Also known as coat protein C and capsid protein C. This makes the ...
109-266 3.73e-98

Alphavirus core protein; Also known as coat protein C and capsid protein C. This makes the literature very confusing. Alphaviruses consist of a nucleoprotein core, a lipid membrane which envelopes the core, and glycoprotein spikes protruding from the lipid membrane.


Pssm-ID: 366379  Cd Length: 156  Bit Score: 309.23  E-value: 3.73e-98
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152  109 ALKLEADRLFDVKNEaGEVIGHALAMEGKVMKPLHVKGTIDHPVLSKLKFTKSSAYDMEFAQLPTNMRSEAFSYTSEHPE 188
Cdd:pfam00944    1 CMKIENDCIFEVKHE-GKVTGYACLVGDKVMKPAHVKGTIDNADLAKLAFKKSSKYDLECAQIPVHMRSDASKYTHEKPE 79
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2129099152  189 GFYNWHHGAVQYSGGRFTVPKGAGGKGDSGRPIMDNTGKVVAIVLGGADEGARTALSVVTWNsKGKTIKTTPEGTEEW 266
Cdd:pfam00944   80 GFYNWHHGAVQYSGGRFTIPTGAGKPGDSGRPIFDNKGRVVAIVLGGANEGTRTALSVVTWN-KDKVTKTTPEGTEEW 156
PRK11633 PRK11633
cell division protein DedD; Provisional
56-102 5.56e-04

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 43.07  E-value: 5.56e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 2129099152   56 QVSRQQQPRQRPAPKPRRQPPKQQQPKSKKTKNPE-KPKQKQPTKSKP 102
Cdd:PRK11633    96 PVEPEPAPVEPPKPKPVEKPKPKPKPQQKVEAPPApKPEPKPVVEEKA 143
PRK12757 PRK12757
cell division protein FtsN; Provisional
52-136 7.41e-04

cell division protein FtsN; Provisional


Pssm-ID: 237191 [Multi-domain]  Cd Length: 256  Bit Score: 42.72  E-value: 7.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152   52 LVIGQVSRQQQPRQRPA-PKPRRQPPKQQQPKSKKTKNPEKPKQKQPtKSKPGKRQRMALKLEADRLFDVK------NEA 124
Cdd:PRK12757   119 VQIQQQAQQQQPPATTAqPQPVTPPRQTTAPVQPQTPAPVRTQPAAP-VTQAVEAPKVEAEKEKEQRWMVQcgsfkgTEQ 197
                           90
                   ....*....|..
gi 2129099152  125 GEVIGHALAMEG 136
Cdd:PRK12757   198 AESVRAQLAFAG 209
PRK01297 PRK01297
ATP-dependent RNA helicase RhlB; Provisional
59-146 1.44e-03

ATP-dependent RNA helicase RhlB; Provisional


Pssm-ID: 234938 [Multi-domain]  Cd Length: 475  Bit Score: 42.59  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2129099152   59 RQQQPRQRPAPKPRRQPPKQQQPKSKKTKN-PEKPKQKQPTKSKPgKRQRMALKLEADRL--FDVKNEAGEVIGHALAME 135
Cdd:PRK01297    17 PAPAPPSPAAAPAPPPPAKTAAPATKAAAPaAAAPRAEKPKKDKP-RRERKPKPASLWKLedFVVEPQEGKTRFHDFNLA 95
                           90
                   ....*....|.
gi 2129099152  136 GKVMKPLHVKG 146
Cdd:PRK01297    96 PELMHAIHDLG 106
PRK12757 PRK12757
cell division protein FtsN; Provisional
43-110 3.18e-03

cell division protein FtsN; Provisional


Pssm-ID: 237191 [Multi-domain]  Cd Length: 256  Bit Score: 40.80  E-value: 3.18e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2129099152   43 QQLTSAVNALVIGQVSRQQQPRQRPAPKPRRQPPKQQQPKSKKTKNPEkPKQKQPTKSKPG----KRQRMAL 110
Cdd:PRK12757   117 STVQIQQQAQQQQPPATTAQPQPVTPPRQTTAPVQPQTPAPVRTQPAA-PVTQAVEAPKVEaekeKEQRWMV 187
PHA03247 PHA03247
large tegument protein UL36; Provisional
56-106 4.18e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 4.18e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2129099152   56 QVSRQQQPRQRPAPKPRRQPPKQQQPKSKKTKNPEKPKQKQPTKSKPGKRQ 106
Cdd:PHA03247  2890 AVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ 2940
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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