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Conserved domains on  [gi|2160511177|gb|UFX54205|]
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NADH dehydrogenase subunit 6, partial (mitochondrion) [Cryptotis merriami]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-138 8.24e-65

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 194.64  E-value: 8.24e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2160511177   1 CGIVLNYGGSFLGLMVFLIYLGGMLVVFGYTTAMAMEEYPEVWVSNNTVLFTFLLGLMGESMLIAYLLledEDLEFEIVL 80
Cdd:MTH00109   41 CGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPETWVSNKVVLGALLLGLLMELLLVLYVL---KDDEVEVVF 117

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2160511177  81 NFNGEGDWVIYDTGDSGFFSEEYMGIAALYSYGFWLAIVSGWSLVTCIVVIMEITRGN 138
Cdd:MTH00109  118 NFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSLFIGVFVIIEITRGN 175
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-138 8.24e-65

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 194.64  E-value: 8.24e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2160511177   1 CGIVLNYGGSFLGLMVFLIYLGGMLVVFGYTTAMAMEEYPEVWVSNNTVLFTFLLGLMGESMLIAYLLledEDLEFEIVL 80
Cdd:MTH00109   41 CGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPETWVSNKVVLGALLLGLLMELLLVLYVL---KDDEVEVVF 117

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2160511177  81 NFNGEGDWVIYDTGDSGFFSEEYMGIAALYSYGFWLAIVSGWSLVTCIVVIMEITRGN 138
Cdd:MTH00109  118 NFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSLFIGVFVIIEITRGN 175
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
1-134 3.32e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 46.34  E-value: 3.32e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2160511177   1 CGIVLNYGGSFLGLMVFLIYLGGMLVVFGYTTAMAMEEYPEVWVSNNTVLFTFLLGLmgesmLIAYLLLededlefeIVL 80
Cdd:pfam00499  24 AGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL-----LLLALLL--------LVL 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2160511177  81 NFNGEGDWViyDTGDSGFFSEEYMGIAALYSYGFWLaIVSGWSLVTCIVVIMEI 134
Cdd:pfam00499  91 LSASLTPAA--AAAAPDVGNIEAIGELLFTDYLLPF-ELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-138 8.24e-65

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 194.64  E-value: 8.24e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2160511177   1 CGIVLNYGGSFLGLMVFLIYLGGMLVVFGYTTAMAMEEYPEVWVSNNTVLFTFLLGLMGESMLIAYLLledEDLEFEIVL 80
Cdd:MTH00109   41 CGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPETWVSNKVVLGALLLGLLMELLLVLYVL---KDDEVEVVF 117

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2160511177  81 NFNGEGDWVIYDTGDSGFFSEEYMGIAALYSYGFWLAIVSGWSLVTCIVVIMEITRGN 138
Cdd:MTH00109  118 NFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSLFIGVFVIIEITRGN 175
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-137 4.79e-22

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 85.96  E-value: 4.79e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2160511177   1 CGIVLNYGGSFLGLMVFLIYLGGMLVVFGYTTAMAMEEYPEVWVSNntVLFTFLLGLMGESMLIAYLLLEDEdlefeivl 80
Cdd:MTH00138   40 CGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPESWGSW--SVLGYVVGYLVGVVLAAGLFWGGW-------- 109

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2160511177  81 nfnGEGDWVI-YDTGDSGFFSEEYMGIAALYSYGFWLAIVSGWSLVTCIVVIMEITRG 137
Cdd:MTH00138  110 ---YEGSWVVvDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLELTRG 164
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-137 2.51e-20

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 81.43  E-value: 2.51e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2160511177   1 CGIVLNYGGSFLGLMVFLIYLGGMLVVFGYTTAMAMEEYPEVWVSNNTVLFTFLLGLMgesMLIAYLLLEDEDLEFEIVL 80
Cdd:MTH00065   40 CLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPEAWGSWSVLVYVLFYLLL---LIVGYILFGCNFSLEFLFT 116

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2160511177  81 NFNGEGDWVIYDTGdsgffseeymGIAALYSYGFWLAIVSGWSLVTCIVVIMEITRG 137
Cdd:MTH00065  117 NYDTEFSVVGYDWG----------GVGLMYSSGGWFLMISGWVLLLTLFVVLEVTRG 163
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-137 2.72e-15

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 68.24  E-value: 2.72e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2160511177   1 CGIVLNYGGSFLGLMVFLIYLGGMLVVFGYTTAMAMEEYPEVWVSNNTVLFTFLLGLMGESMLIAYLLLEDEdlefeivl 80
Cdd:MTH00115   40 CGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPEAWGDWGVVGYVVGFVLVVVVVGVVVGGLWGM-------- 111

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2160511177  81 nfnGEGDWVIYDTGDSGFFSEEYMGIAALYSYGFWLAIVSGWSLVTCIVVIMEITRG 137
Cdd:MTH00115  112 ---EGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVLELVRG 165
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-137 4.11e-12

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 60.00  E-value: 4.11e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2160511177   1 CGIVLNYGGSFLGLMVFLIYLGGMLVVFGYTTAMAMEEYPEVWVSNNtVLFTFLLGLMGESMLIAYLLLEDEDLEFEIVL 80
Cdd:MTH00214   40 CFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPESWGGWS-VLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVD 118

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2160511177  81 NFNGEGdwviydtgdsgffseeYMGIAALYSYGFWLAIVSGWSLVTCIVVIMEITRG 137
Cdd:MTH00214  119 EANNLD----------------LSGVSDLYSRGFFLLLLGGVVLFLVLFVVLELVRG 159
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
1-134 3.32e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 46.34  E-value: 3.32e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2160511177   1 CGIVLNYGGSFLGLMVFLIYLGGMLVVFGYTTAMAMEEYPEVWVSNNTVLFTFLLGLmgesmLIAYLLLededlefeIVL 80
Cdd:pfam00499  24 AGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL-----LLLALLL--------LVL 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2160511177  81 NFNGEGDWViyDTGDSGFFSEEYMGIAALYSYGFWLaIVSGWSLVTCIVVIMEI 134
Cdd:pfam00499  91 LSASLTPAA--AAAAPDVGNIEAIGELLFTDYLLPF-ELASVLLLVALVGAIVL 141
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-138 4.39e-07

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 46.44  E-value: 4.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2160511177   1 CGIVLNYGGSFLGLMVFLIYLGGMLVVFGYTTAMAMEEYPEVWVSNNTVLFTFLLGLMgesmliaylllededlefeIVL 80
Cdd:MTH00045   38 CLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSVSNLGEVLVLSLLLSLW-------------------VFI 98

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2160511177  81 NFNGEGDWVIYDTGDSGFFSEeyMGIAALYSYGFWLAIVSGWSLVTCIVVIMEITRGN 138
Cdd:MTH00045   99 SFDNFLELSNNNWSLVSLSDL--VGSSELYNSGGLYLLLGGFILLVALVVALVISFGH 154
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 1-91 3.45e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 35.63  E-value: 3.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2160511177   1 CGIVLNYGGSFLGLMVFLIYLGGMLVVFGYTTAMameeYPEVWVSNNTVLFTFLLGLMGESMLIAYLLLEDEDLEFEIVL 80
Cdd:MTH00152   38 CVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSL----SPNPLFGSNFKFVFFSLTLFGFLGLFFFFLYLYSSGGLSLSS 113

                          90
                  ....*....|.
gi 2160511177  81 NFNGEGDWVIY 91
Cdd:MTH00152  114 LFDGSSGSLSF 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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