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Conserved domains on  [gi|2220543591|gb|UOK93157|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Auriparus flaviceps]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 7.70e-161

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 453.51  E-value: 7.70e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   1 MNPQAKLVFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWA 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  81 TGQWDITQLTHPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPTLLTTMAIL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 161 SLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLYTLMTATVFLSLNSIKALKLSTLMTTWTKTPAL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 241 TTMLLLVLLSLAGLPPLTGFLPKWLIIQELTKQDMAVTATTISLLSLLGLFFYLRLAYCATITLPPHTTNHMKQWHTNKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....*.
gi 2220543591 321 VNPMIATLFALSIALLPISPMLPTIF 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 7.70e-161

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 453.51  E-value: 7.70e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   1 MNPQAKLVFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWA 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  81 TGQWDITQLTHPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPTLLTTMAIL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 161 SLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLYTLMTATVFLSLNSIKALKLSTLMTTWTKTPAL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 241 TTMLLLVLLSLAGLPPLTGFLPKWLIIQELTKQDMAVTATTISLLSLLGLFFYLRLAYCATITLPPHTTNHMKQWHTNKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....*.
gi 2220543591 321 VNPMIATLFALSIALLPISPMLPTIF 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 7.01e-25

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 102.01  E-value: 7.01e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  23 SNHWVLAWTGLEINTLAILPLI-SKSHHPRAIEAATKYFLVQATASALVLFASMTNAWATGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  91 HPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPT------LLTTMAILSLAL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 165 GGWMGLNQTQIRKILAFSSISHLGWM----AAIIVYSPKLTLLNFYLYTLMTATVFLSLNSIKALKLST-----LMTTWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMlialGAGTIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTrnirdYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2220543591 236 KTPALTTMLLLVLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-270 1.90e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 103.27  E-value: 1.90e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  14 LLGTTITISSNHWVLAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLVQATASALVLF-ASMTNAwATGQWDITQL-- 89
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIaa 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  90 ---THPTSSLILTSALAM-------KLGLVPFHFWFPEVLQGSPLITGLLLSTLMK----FPPITLLFMTSPSLNP---T 152
Cdd:COG1007   191 alaAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKiaafAALLRLLVEAFPGLAAdwqL 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 153 LLTTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWM-AAIIVYSPK-LTLLNFYL--YTLMTATVF-----LSLNSIK 223
Cdd:COG1007   271 LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPLgVSAALFYLlaYLFMNLGAFavillLSRKGGE 350

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 2220543591 224 ALKLSTLMTTWTKTPALTTMLLLVLLSLAGLPPLTGFLPKWLIIQEL 270
Cdd:COG1007   351 AEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAA 397
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-275 2.52e-21

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 94.24  E-value: 2.52e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  14 LLGTTITISSNHWVLAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLVQATASALVLFASMTNAWATGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  93 TSSLILT------------SALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMK---FPPITLLFMTSPS----LNPTL 153
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKiaiFAVFLRLFLYILFgfseAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 154 LTTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLN--FYL--YTLMTATVFLSLNSIKALK--- 226
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlFYIfiYALMSLGAFGVLSLLRSYKdew 351

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2220543591 227 ---LSTLMTTWTKTPALTTMLLLVLLSLAGLPPLTGFLPKWLIIQELTKQDM 275
Cdd:TIGR01770 352 ieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGL 403
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 7.70e-161

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 453.51  E-value: 7.70e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   1 MNPQAKLVFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWA 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  81 TGQWDITQLTHPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPTLLTTMAIL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 161 SLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLYTLMTATVFLSLNSIKALKLSTLMTTWTKTPAL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 241 TTMLLLVLLSLAGLPPLTGFLPKWLIIQELTKQDMAVTATTISLLSLLGLFFYLRLAYCATITLPPHTTNHMKQWHTNKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....*.
gi 2220543591 321 VNPMIATLFALSIALLPISPMLPTIF 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 4.23e-128

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 370.41  E-value: 4.23e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   1 MNPQAKLVFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWA 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  81 TGQWDITQLTHPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPTLLTTMAIL 160
Cdd:MTH00070   81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 161 SLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLYTLMTATVFLSLNSIKALKLSTLMTTWTKTPAL 240
Cdd:MTH00070  161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 241 TTMLLLVLLSLAGLPPLTGFLPKWLIIQELTKQDMAVTATTISLLSLLGLFFYLRLAYCATITLPPHTTNHMKQWHTNKP 320
Cdd:MTH00070  241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320

                         330       340
                  ....*....|....*....|....*.
gi 2220543591 321 VNPMIATLFALSIALLPISPMLPTIF 346
Cdd:MTH00070  321 TNNLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-346 5.29e-127

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 367.59  E-value: 5.29e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   1 MNPQAKLVFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWA 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  81 TGQWDITQLTHPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSlNPTLLTTMAIL 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 161 SLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLYTLMTATVFLSLNSIKALKLSTLMTTWTKTPAL 240
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 241 TTMLLLVLLSLAGLPPLTGFLPKWLIIQELTKQDMAVTATTISLLSLLGLFFYLRLAYCATITLPPHTTNHMKQWHTNKP 320
Cdd:MTH00135  240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                         330       340
                  ....*....|....*....|....*..
gi 2220543591 321 VNPM-IATLFALSIALLPISPMLPTIF 346
Cdd:MTH00135  320 QLTLpLAISTTATLMLLPLTPAILALL 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-346 2.68e-116

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 340.28  E-value: 2.68e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   1 MNPQAKLVFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWA 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  81 TGQWDITQLTHPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPTLLTTMAIL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 161 SLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLYTLMTATVFLSLNSIKALKLSTLMTTWTKTPAL 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 241 TTMLLLVLLSLAGLPPLTGFLPKWLIIQELTKQDMAVTATTISLLSLLGLFFYLRLAYCATITLPPhTTNHMK-QWH-TN 318
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFP-STNNMKmKWQfEN 319

                         330       340
                  ....*....|....*....|....*...
gi 2220543591 319 KPVNPMIATLFALSIALLPISPMLPTIF 346
Cdd:MTH00105  320 TKPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-346 2.76e-94

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 284.17  E-value: 2.76e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   1 MNPQAKLVFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWA 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  81 TGQWDITQLTHPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPTLLTTMAIL 160
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 161 SLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLYTLMTATVFLSLNSIKALKLSTLMTTWTKTPAL 240
Cdd:MTH00200  161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 241 TTMLLLVLLSLAGLPPLTGFLPKWLIIQELTKQDMAVTATTISLLSLLGLFFYLRLAYCATITLPPHTTNHMKQWHTNKP 320
Cdd:MTH00200  241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                         330       340
                  ....*....|....*....|....*.
gi 2220543591 321 VNPMIATLFALSIALLPISPMLPTIF 346
Cdd:MTH00200  321 SNLLVGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-267 1.43e-76

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 239.06  E-value: 1.43e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   1 MNPQAKLVFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWA 80
Cdd:MTH00041    1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  81 TGQWDITQLTHPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPTLLTTMAIL 160
Cdd:MTH00041   81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 161 SLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLYTLMTATVFLSLNSIKALKLSTLMTTWTKTPAL 240
Cdd:MTH00041  161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                         250       260
                  ....*....|....*....|....*..
gi 2220543591 241 TTMLLLVLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00041  241 AFLFILSILSLGGLPPLTGFLNKFISL 267
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-275 1.53e-54

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 181.56  E-value: 1.53e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   1 MNPQAKLVFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWa 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  81 tgqwdITQLTHPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTspsLNPTLLTTMAIL 160
Cdd:MTH00160   81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 161 SLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLYTLMTATVFLSLNSIKALKLSTLMTTWTKTPAL 240
Cdd:MTH00160  153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2220543591 241 TTMLLLVLLSLAGLPPLTGFLPKWLIIQELTKQDM 275
Cdd:MTH00160  233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNM 267
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 5-275 9.58e-46

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 158.51  E-value: 9.58e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   5 AKLVFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWATGQW 84
Cdd:MTH00144    5 SNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  85 DitqlthptSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNP-TLLTTMAILSLA 163
Cdd:MTH00144   85 F--------SMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSAL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 164 LGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLYTLMTATVFLSLNSiKALKLSTLMTTWTKTPALTTM 243
Cdd:MTH00144  157 VGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWS-GDSGSMKDLGSLKPSYKTGLS 235

                         250       260       270
                  ....*....|....*....|....*....|..
gi 2220543591 244 LLLVLLSLAGLPPLTGFLPKWLIIQELTKQDM 275
Cdd:MTH00144  236 IISLLLSLGGLPPFLGFCSKLLVLISSMESSP 267
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 7-275 6.20e-43

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 151.47  E-value: 6.20e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   7 LVFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASmtnawaTGQWDI 86
Cdd:MTH00011    9 FLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  87 TQLTHPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPTLLTTMAILSLALGG 166
Cdd:MTH00011   83 PSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGG 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 167 WMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLYTLMTATVFLSLNSIKALKLSTLMTTWTKTPALTTMLLL 246
Cdd:MTH00011  163 LGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFI 242

                         250       260
                  ....*....|....*....|....*....
gi 2220543591 247 VLLSLAGLPPLTGFLPKWLIIQELTKQDM 275
Cdd:MTH00011  243 MLLSLGGLPPFTGFMPKLMAIETLTSNSM 271
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-270 1.83e-35

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 131.33  E-value: 1.83e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   8 VFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWATgqwdit 87
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL------ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  88 qLTHPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLfmTSPSLNPTLLTTMAILSLALGGW 167
Cdd:MTH00197   76 -YLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLIL--AFNSSSFMGLLICSVLSSLIGGI 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 168 MGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLYTLMTATVFLSLNSIKALKLSTLMTTWTKTPALTTMLLLV 247
Cdd:MTH00197  153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLS 232

                         250       260
                  ....*....|....*....|...
gi 2220543591 248 LLSLAGLPPLTGFLPKWLIIQEL 270
Cdd:MTH00197  233 FLSLGGLPPLSGFFLKWLILTSL 255
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-267 8.47e-26

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 105.88  E-value: 8.47e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  13 LLLGTTITISSNHWVLAWTGLEINTLAILPLI-SKSHHPRAIEAATKYFLVQATASALVLFA-------------SMTNA 78
Cdd:MTH00196    2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  79 WATGQWDITQLTHPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNptLLTTMA 158
Cdd:MTH00196   82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 159 ILSLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVY----SPKLTLLNFYLYTLMTATVF---LSLNSIKALkLSTLM 231
Cdd:MTH00196  160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfeSIQASLVYLFIYIIMSICVFsiiLALNVYKNL-IIEFS 238

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 2220543591 232 TTWTKTPALTTMLLLVLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00196  239 GLSRRLPILAITLALTFLSIAGIPPLVGFLGKWLIL 274
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 7.01e-25

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 102.01  E-value: 7.01e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  23 SNHWVLAWTGLEINTLAILPLI-SKSHHPRAIEAATKYFLVQATASALVLFASMTNAWATGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  91 HPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPT------LLTTMAILSLAL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 165 GGWMGLNQTQIRKILAFSSISHLGWM----AAIIVYSPKLTLLNFYLYTLMTATVFLSLNSIKALKLST-----LMTTWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMlialGAGTIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTrnirdYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2220543591 236 KTPALTTMLLLVLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-270 1.90e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 103.27  E-value: 1.90e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  14 LLGTTITISSNHWVLAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLVQATASALVLF-ASMTNAwATGQWDITQL-- 89
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIaa 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  90 ---THPTSSLILTSALAM-------KLGLVPFHFWFPEVLQGSPLITGLLLSTLMK----FPPITLLFMTSPSLNP---T 152
Cdd:COG1007   191 alaAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKiaafAALLRLLVEAFPGLAAdwqL 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 153 LLTTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWM-AAIIVYSPK-LTLLNFYL--YTLMTATVF-----LSLNSIK 223
Cdd:COG1007   271 LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPLgVSAALFYLlaYLFMNLGAFavillLSRKGGE 350

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 2220543591 224 ALKLSTLMTTWTKTPALTTMLLLVLLSLAGLPPLTGFLPKWLIIQEL 270
Cdd:COG1007   351 AEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAA 397
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 13-267 2.35e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 103.17  E-value: 2.35e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  13 LLLGTTITISSNHWVLAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLVQATASALVLFASMTNAWATGQWDI----T 87
Cdd:MTH00199  106 VALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIqginS 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  88 QLTHPTSSLILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPTLLTtmAILSLALGGW 167
Cdd:MTH00199  186 ILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSIIYGAI 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 168 MGLNQTQIRKILAFSSISHLG---WMAAIIVY-SPKLTLLNFYLYTLMTATVF---LSLNSIKALkLSTLMTTWTKTPAL 240
Cdd:MTH00199  264 GALNQTKIKRLLAYSGIGHMGfilFGVAIGSFeSIQASLIYMIIYVIMSICSFsiiLSLKLTKGL-IVEVSGLSRKNPVI 342

                         250       260
                  ....*....|....*....|....*..
gi 2220543591 241 TTMLLLVLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00199  343 ALTLALTFLSIAGIPPLAGFLSKWLIL 369
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-275 2.52e-21

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 94.24  E-value: 2.52e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  14 LLGTTITISSNHWVLAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLVQATASALVLFASMTNAWATGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  93 TSSLILT------------SALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMK---FPPITLLFMTSPS----LNPTL 153
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKiaiFAVFLRLFLYILFgfseAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 154 LTTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLN--FYL--YTLMTATVFLSLNSIKALK--- 226
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlFYIfiYALMSLGAFGVLSLLRSYKdew 351

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2220543591 227 ---LSTLMTTWTKTPALTTMLLLVLLSLAGLPPLTGFLPKWLIIQELTKQDM 275
Cdd:TIGR01770 352 ieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGL 403
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-268 4.98e-19

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 87.57  E-value: 4.98e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  14 LLGTTITISSNHWVLAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLVQATASALVLF-ASMTNAwATGQWDITQLTH 91
Cdd:PRK05777  113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYgMSLLYG-ATGSLSFAGIAK 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  92 PTSS------------LILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMK---FPPIT-LLFMTSPSLNPT--- 152
Cdd:PRK05777  192 ALADgsgnsllllfglVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKiaaFAVLLrLLVVAFGGLSEDwqq 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 153 LLTTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWM-AAIIVYSPK-LTLLNFYL--YTLMTATVFLSLNSIK----- 223
Cdd:PRK05777  272 VLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlVGLAAGTAEgYSAVLFYLlaYLFMTLGAFGVISLLRrkgge 351

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2220543591 224 ALKLSTLMTTWTKTPALTTMLLLVLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:PRK05777  352 AESISDFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFE 396
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 13-279 1.54e-16

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 80.19  E-value: 1.54e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  13 LLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWATGQWDITQLTHP 92
Cdd:COG0651   116 LLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAAR 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  93 TSSL----------ILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPI-------TLLFMTSPSLNP-TLL 154
Cdd:COG0651   196 LAELdpglllaafaLLLVGFGIKAALFPLHFWLPDAYPAAPSPVSALLSGLLTKVGVyailrvlTLLFGADPALFLgTLL 275

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 155 TTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLY----TLMTATVFLSLNSI----KALK 226
Cdd:COG0651   276 LVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHllnhALAKALLFLAAGAIeratGTRD 355

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2220543591 227 LSTLMTTWTKTPALTTMLLLVLLSLAGLPPLTGFLPKWLIIQELTKQDMAVTA 279
Cdd:COG0651   356 LDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLA 408
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 3-190 6.25e-16

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 78.75  E-value: 6.25e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   3 PQAKLVFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAI---------EAATKYFLVQATASALVLFA 73
Cdd:MTH00198  187 PRSGFALVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFG 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  74 SMTNAWATGQ----WDITQLTHPTSS----------LILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPI 139
Cdd:MTH00198  267 CALYFGFTGNegmlGTILSATLETTNielrqgslgyLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVY 346

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2220543591 140 TLLfmTSPSLNPTLLTTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWM 190
Cdd:MTH00198  347 ILL--TSLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFI 395
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-208 6.64e-12

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 66.18  E-value: 6.64e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  51 RAIEAATKYFLVQATASALVLFA-SMTNAWATGQWDI---------TQLTHPTSSLI----LTSALAMKLGLVPFHFWFP 116
Cdd:CHL00049  159 RSNEATMKYLLMGGASSSILVYGfSWLYGLSGGEIELqeivnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTP 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 117 EVLQGSPL-----------ITGLLLSTLMkfppITLLFMTSPSLNPTLLTTMAILSLALGGWMGLNQTQIRKILAFSSIS 185
Cdd:CHL00049  239 DVYEGSPTpvvaflsvtskVAASALATRI----FDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIG 314

                         170       180       190
                  ....*....|....*....|....*....|
gi 2220543591 186 HLGW-MAAIIV------YSPKLTLLNFYLY 208
Cdd:CHL00049  315 QIGYvIIGIIVgdsndgYASMITYMLFYIF 344
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-188 1.57e-11

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 65.07  E-value: 1.57e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  50 PRAIEAATKYFLVQATASALVLF-ASMTNAWATGQwdiTQLTHPTSSLI----LTSALAM---------KLGLVPFHFWF 115
Cdd:PRK02504  157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGS---TQLSAIALALItspsLGLALALvfviagiafKISAVPFHQWT 233

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 116 PEVLQGSPLITGLLLSTLMKFP----PITLLFMTSPSLNP---TLLTTMAILSLALGGWMGLNQTQIRKILAFSSISHLG 188
Cdd:PRK02504  234 PDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDEqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAG 313
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-266 3.03e-10

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 61.27  E-value: 3.03e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  33 LEINTLAILPLIS-KSHHPRAIEAATKYFLVQATASALVLFA---------SMTNAWATGQWDITQLTHPTSSL-ILTSA 101
Cdd:PRK08376  150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGiallygqygTLNMAYLAVKMSENPTVVAKIALaLFIAG 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 102 LAMKLGLVPFHFWFPEVLQGSPL-ITGLLLstLMKFPPITLLF-----MTSPSLNPT----LLTTMAILSLALGGWMGLN 171
Cdd:PRK08376  230 LAMKSGAVPVHMWLPDAYPAAPSsISAMLL--VIKQAGLYALArvlfsIYGPAINLAtvgwVIIILGCLTMFVGVAMAVV 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 172 QTQIRKILAFSSISHLGWM-----AAIIVYSPklTLLNFYLYTLMTATVFLSLNSI--KAL------------------K 226
Cdd:PRK08376  308 QKDVKRLLAYHSVSQIGYMllglgVGLAALGD--PAMASYGEIALAGGIYHIVNHAlyKALlfltagaviyetgtrnlnE 385

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 2220543591 227 LSTLMTTWTKTpalTTMLLLVLLSLAGLPPLTGFLPKWLI 266
Cdd:PRK08376  386 LGGLARTMPKT---TIAFLIGAAAIVGLPPFNGFASKWLI 422
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-188 3.37e-10

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 60.87  E-value: 3.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  49 HPRAIEAATKYFLVQATASALVLFASMTNAWATGQW--DITQLTHPTSSLILTS--------ALAMKLGLVPFHFWFPEV 118
Cdd:COG1008   156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAAPLPLTAQLllflaffiAFAVKVPMFPFHTWLPDA 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 119 LQ-----GSPLITGLLLST---------LMKFPPITLLFMTspslnptLLTTMAILSLALGGWMGLNQTQIRKILAFSSI 184
Cdd:COG1008   236 HVeaptaGSVLLAGVLLKMggygllrfaLPLFPEASAYFAP-------LLAALGVIGIIYGALVALAQTDLKRLIAYSSV 308


                  ....
gi 2220543591 185 SHLG 188
Cdd:COG1008   309 SHMG 312
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 13-219 4.45e-08

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 54.38  E-value: 4.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  13 LLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATA------SALVLFASMTNAWATGQWDI 86
Cdd:PRK08676  111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNW 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  87 TQLTHPTS----SLILTSALAM------KLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPT---- 152
Cdd:PRK08676  191 TELAAHASllspSVLGASFLFIfigflaKSGLVPFHTWLPAAYAKAPSVVSALLSGTVLNIGIYGILRLSALLRQSgaae 270

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2220543591 153 ----LLTTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLYTLMTATVFLSL 219
Cdd:PRK08676  271 qfsnVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHMLAHSLVKSGL 341
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-270 1.41e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 52.96  E-value: 1.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  33 LEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFA-SMTNAwATGQWDITQL--------THPTSSLILTSALA 103
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGvGLLYG-VTGTLNMADLagalaenpTVVTAFGFVLLALA 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 104 MKLGLVPFHFWFPEVLQG-SPLITGLLLSTLMK----------FPPITLLFMTSPSLNpTLLTTMAILSLALGGWMGLNQ 172
Cdd:PRK08375  214 LKAAVFPLHTWLPRAYPAaPPVVTALLSGLVTKvavyaliriyFTVFGGDFRFALGLG-WLLAVLALLSMLVGSLAALGQ 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 173 TQIRKILAFSSISHLGWMAAIIVYSPKLTLLN--FYL--YTLMTATVFLSLNSI----KALKLSTLMTTWTKTPALTTML 244
Cdd:PRK08375  293 DDVKRVLAYSTVSQMGYILLGLALLTPLALAAglLHLlhHALMKGALFLAAGAIevtyGTRRLSELSGLGRRMPLTAAAF 372

                         250       260
                  ....*....|....*....|....*.
gi 2220543591 245 LLVLLSLAGLPPLTGFLPKWLIIQEL 270
Cdd:PRK08375  373 AVASLSLIGVPPTSGFVSKWYLVVGA 398
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-190 1.52e-07

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 52.63  E-value: 1.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  50 PRAIEAATKYFLVQATASALVLFASMTNAWATGQ-WDITQL-THPTSS-------LILTSALAMKLGLVPFHFWFPEV-- 118
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGtFDLLELlNLPLPFgvqtwlfLAFFIAFAVKVPLFPLHTWLPDAhv 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 119 ---LQGSPLITGLLLST---------LMKFPPITLLFMtspslnpTLLTTMAILSLALGGWMGLNQTQIRKILAFSSISH 186
Cdd:TIGR01972 232 eapTAGSVILAGVLLKMgtygflrfnLPLFPDASLYFA-------PVLAALGVIAIIYGALIALAQTDIKRLIAYSSISH 304


                  ....
gi 2220543591 187 LGWM 190
Cdd:TIGR01972 305 MGFV 308
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 7-190 3.85e-07

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 51.69  E-value: 3.85e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   7 LVFTVSLLLgttITISSNHWVLaWTGLEINTLAILPLISKSHH-PRAIEAATKYFLVQATASALVLFASMTNAWATGQWD 85
Cdd:COG1009   118 LLFMAAMLG---LVLSDNLLLL-FVFWELVGLCSYLLIGFWYEkPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLN 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  86 ITQL-----THPTSSLILTSALAM------KLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSP--SLNPT 152
Cdd:COG1009   194 FSELlaaapTILSSPLLTLILLLLllgafgKSAQFPLHFWLPDAMEGPTPVSALLHAATMVKAGVYLLARLSPlfALSPV 273

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2220543591 153 LLTTMAILSLA---LGGWMGLNQTQIRKILAFSSISHLGWM 190
Cdd:COG1009   274 WLTVVAIIGAItalFAALIALAQTDIKRVLAYSTVSQLGYM 314
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 50-188 6.93e-07

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 50.59  E-value: 6.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  50 PRAIEAATKYFLVQATASALVLFASMT----NAWATGQWDITQLTHPTSS--------LILTSALAMKLGLVPFHFWFPE 117
Cdd:PRK05846  157 KNRIYAATKFFLYTLLGSLLMLVAIIYlvvvYYNATGTFDIADLLNLPLPpgvqywlfLAFFIAFAVKMPMFPLHTWLPD 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 118 VLQ-----GSPLITGLLLST---------LMKFPPITLLFMTspslnptLLTTMAILSLALGGWMGLNQTQIRKILAFSS 183
Cdd:PRK05846  237 AHVqaptaGSVLLAGILLKMgaygllrfsLPLFPDASHEFAP-------IIITLGVIAIIYGALVALAQTDIKKLIAYSS 309


                  ....*
gi 2220543591 184 ISHLG 188
Cdd:PRK05846  310 ISHMG 314
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 96-194 9.04e-07

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 50.69  E-value: 9.04e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  96 LILTSALAmKLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLL------FMTSPSLNPTLLTtMAILSLALGGWMG 169
Cdd:PRK12644  208 LILVGALS-KSAIVPFHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLVarlapgFADVPVWRPTVLV-LGLATMLLGGWRA 285

                          90       100
                  ....*....|....*....|....*
gi 2220543591 170 LNQTQIRKILAFSSISHLGWMAAII 194
Cdd:PRK12644  286 LRQHDLKLILAYGTVSQLGFLTVLV 310
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 9-191 9.23e-07

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 50.31  E-value: 9.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   9 FTVSLLLgttiTISSNHWVLAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFAS----------MTNA 78
Cdd:PRK06458  117 FLFTMLL----ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTilvyanaatvMGDG 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  79 WATGQW-DITQLTHPTSSLILTSALAM-------KLGLVPFHFWFPEVLQGSP-----LITGLLLST----LMKFPPITL 141
Cdd:PRK06458  193 EMAILWtELLKHASLLDPTLMKLAFVFlligfgtKVGLFPMHAWLPDAHSEAPspvsaLLSGVLLNValyaVLRYYILID 272

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2220543591 142 LFMtSPSLNPTLLTTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWMA 191
Cdd:PRK06458  273 AAI-GSDFPGRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIA 321
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
53-268 5.16e-06

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 48.02  E-value: 5.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  53 IEAATKYFLVQATASALVLFASMTNAWATGQWDITQL-----------THPTSSLILTSALAMKLGLVPFhFWFPEVLQG 121
Cdd:PRK12663  157 LRGAIKYVVLNLIGSWLFLLGIGLLYGTFGTLNMAHIamrlndmgdtaTLTTIALLFLLAFGMKAALFPF-MWLPAAYHT 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 122 SPLITGLLLSTLMK-------FPPITLLFMTSPSLNPTLLTTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWM-AAI 193
Cdd:PRK12663  236 PNTEVAALFAALLTkvgiyalIRVFTLLFPQERELLHPLLATMAAITMVIGALGALAYKDIRRIAGYQVISSIGFIlLGL 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 194 IVYSPK-LTLLNFYLY---TLMTAtVFLSLNSIKAL----KLSTLMTTWTKTPALTTMLLLVLLSLAGLPPLTGFLPKWL 265
Cdd:PRK12663  316 ALGTPAgINGAIFYLVhdmVVKTA-LFLIAGSLVRLtgyrSLQYLGGLYRKEPLFGALFLILIFAIGGLPPFSGFWGKVL 394


                  ...
gi 2220543591 266 IIQ 268
Cdd:PRK12663  395 LVQ 397
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 2-279 8.34e-06

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 47.30  E-value: 8.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   2 NPQAKLVFTVSLLLGTTITISSNHWVLAWTGLEINTLAILPLISKSHHpRAIEAATKYFLVQATASALVLFASMTNAWAT 81
Cdd:PRK08668   96 NDAYFNMFALMSLAGVLGVFLANDLLTLYIFWEIMTFSSFMMVPMGKK-ESRKASLKYFVLSAIGAYAMLYAIFLIYAKT 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  82 GQWDIT-------QLTHPTSSLI----LTSALAMKLGLVPFHFWFPE-----------VLQG--SPLITGLLLSTLMKFP 137
Cdd:PRK08668  175 GTFDFAdisqgliNDTSTGFALIvflfLLAFGVAKAGIFPLHVWAPDayseapqsfsaVLSGqlSKLGAYGFLLVLYVLP 254

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 138 PITLL-----FMTSPSLNpTLLTTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWmaaIIVYSPKLTLLNF------- 205
Cdd:PRK08668  255 GTKLFsefgtYRGVPLFN-YILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGY---ILVGLGLGTSLGFagglfhv 330

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2220543591 206 YLYTLMTATVFLSLNSI----KALKLSTLMTTWTKTPALTTMLLLVLLSLAGLPPLTGFLPKWLIIQELTKQDMAVTA 279
Cdd:PRK08668  331 FNHALFKGLFFLIFAAViyrtGTTKISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITA 408
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-192 1.23e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 46.87  E-value: 1.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  33 LEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWATGQWDITQLTH--PTSSLILTSALAMKLGLVP 110
Cdd:PRK07234  123 LEVLSIATFLLVAYPRTDRAIWVGLRYLFYSNVAMLFYLIGAVLVYQANGTFAFSGLATadPEAFALIALGLLVKGGIFV 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 111 FHFWFPEVLQGSPLITGLLLSTLMK----FPPITLLFMtSPSLNPtLLTTMAILSLALGGWMGLNQTQIRKILAFSSISH 186
Cdd:PRK07234  203 SGLWLPLTHSEAEPPVSALLSGVVVkagvFPLVRCALD-VPGLDL-IVRIFGVGTALLGVLFALLEKDLKRMLAFSTISQ 280


                  ....*.
gi 2220543591 187 LGWMAA 192
Cdd:PRK07234  281 LGFILA 286
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
55-203 1.84e-05

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 46.23  E-value: 1.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  55 AATKYFLVQATASALVLFASMTNAWATG--QWDITQL---THPTSSLILTSA-----LAMKLGLVPFHFWFPEV-LQGSP 123
Cdd:PRK06473  158 AATKFLLYTAISGILILVSFLGLVWLSGasSFDYEPLrshTLPLSTQLLLLApilvgFGIKIPLVPFHTWLPDAhVEAST 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 124 LITGLLLSTLMKFPPITLL------FMTSPSLNPTLLTTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYS 197
Cdd:PRK06473  238 PVSVLLAGVLLKLGTYGLLrfgvglFPEAWVYLAPWLATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILLAAAAA 317


                  ....*.
gi 2220543591 198 PKLTLL 203
Cdd:PRK06473  318 TPLSIL 323
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
52-190 2.87e-05

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 45.78  E-value: 2.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  52 AIEAATKYFLVQATASALVLFASMTNAWATGQWDITQLTHPTSSLILTSALAMKLGLV----------------PFHFWF 115
Cdd:PRK07376  171 AADAAQKAFVVNRVGDFGLLLGILGLFWATGSFDFDGIADRLSELVSSGAVSGWLALLlcilvflgpmaksaqfPLHVWL 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 116 PEVLQGSPLITGLLLSTLMKFPPITLLFMTSP--SLNPTLLTTMAI---LSLALGGWMGLNQTQIRKILAFSSISHLGWM 190
Cdd:PRK07376  251 PDAMEGPTPISALIHAATMVAAGVFLVARMYPvfEQFPAVMTVIAWtgaITAFLGASIALTQNDIKKGLAYSTISQLGYM 330
PRK12650 PRK12650
DUF4040 family protein;
27-194 3.75e-05

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 45.42  E-value: 3.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  27 VLAWTGLEINTLAILPLISKSHhPRAIEAATKYFLVQATASALVLFASMTNAWATGQWDITQLTHPTS---SLILTSALA 103
Cdd:PRK12650  133 VVLFVAWELVSLASFFLIARSG-SGGEAGSIRTLILTFFGGLTLLAAVAIAATQTGTTSLSGILHSDVwaeKPGLTTVVA 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 104 M--------KLGLVPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSL--NPT---LLTTMAILSLALGGWMGL 170
Cdd:PRK12650  212 VliavaaftKSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFhdVAVwnwLLIIVGMITALMGAVFAV 291

                         170       180
                  ....*....|....*....|....
gi 2220543591 171 NQTQIRKILAFSSISHLGWMAAII 194
Cdd:PRK12650  292 QKTDLKKLTAYSTVSQLGWIVATI 315
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 295-340 7.40e-05

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 39.93  E-value: 7.40e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2220543591 295 RLAYCATITLPPHTTNHMKQWHTNKPVN-PMIATLFALSIALLPISP 340
Cdd:pfam06444   5 RLSYSTTLTLFPNTNNSKMKWRFNSTKNtLLLPTLTTLSILLLPLTP 51
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 48-263 1.01e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 44.05  E-value: 1.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  48 HHPRAIEAATKYFLVQATASALVLFASMTNAWATGQWDITQLTHPTSS---------------LILTSAlAMKLGLVPFH 112
Cdd:PRK12649  156 HRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATILQDSELienikghplflitliLIFIGA-AAKSAQGPFY 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 113 FWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPT-----LLTTMAILSLALGGWMGLNQTQIRKILAFSSISHL 187
Cdd:PRK12649  235 IWLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPIFSGTeawfiLVSGTGMITMVLAGFLAFRQTDIKAILAYSTISQL 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 188 GWMAAIIVYSPK------LTLLNFYLYTLMT--ATVFLsLNSIKALKLST-----LMTTWTKTPALTTMLLLVLLSLAGL 254
Cdd:PRK12649  315 AYLMTMYGYTTYhepglgVAAATFHLLNHATfkACLFL-VAGIVAHEAATrdirkLGGLRKEMPITFIVASIAALAMAGI 393


                  ....*....
gi 2220543591 255 PPLTGFLPK 263
Cdd:PRK12649  394 PPLNGFLSK 402
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
55-203 2.33e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 42.78  E-value: 2.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  55 AATKYFLVQATASALVLFASMTNAWATGQWD------ITQLTHPTSSLILTSAL----AMKLGLVPFHFWFPEV-LQGSP 123
Cdd:PRK07363  158 ASIKFLIYTAVSGLLVLAAFLGIVWLSGSTSfdydaiSTQNLSLNTQLILLTGLllgfGIKIPLVPLHTWLPDAyTEASP 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 124 LITGLLLSTLMKFPPITL------LFMTSPSLNPTLLTTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWMAAIIVYS 197
Cdd:PRK07363  238 AVAILLGGVLAKLGTYGLlrfglqLFPQTWSLVAPGLAIIGTISVIYGALSAIAQKDIKRMVAYSSIGHMGYILVAAAAG 317


                  ....*.
gi 2220543591 198 PKLTLL 203
Cdd:PRK07363  318 TQLSLL 323
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 28-188 3.05e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 42.33  E-value: 3.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  28 LAWtglEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWATGQ--WDITQLT--HPTSSLILTS--- 100
Cdd:PRK12561  114 LMW---ELELVPVYLLISIWGGQKRLYAATKFILYTALASIFILVAGLALALSGDTftFDLAELGakSYPLALELLLyag 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 101 ---ALAMKLGLVPFHFWFPEV-----LQGSPLITGLLLST----LMKFPpITLLFMTSPSLNPtLLTTMAILSLALGGWM 168
Cdd:PRK12561  191 fliAFGVKLPIFPLHTWLPDAhgeasAPVSMILAGVLLKMggyaLIRFN-VQMLPDAHVYFAP-ALAILGVVNIIYGALN 268

                         170       180
                  ....*....|....*....|
gi 2220543591 169 GLNQTQIRKILAFSSISHLG 188
Cdd:PRK12561  269 AFAQDNVKRRLAYSSVSHMG 288
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
34-268 3.12e-04

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 42.33  E-value: 3.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  34 EINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWATGQWDITQ-----LTHPTSSLILTSALAMKLGL 108
Cdd:PRK06277  130 EIAAIVQVGLVIASGTEEAYKAALKYMILGNVAGSILLLGIGFLLASTGTLNITDihnalLVNPTSPVIYGGLLLLIFGL 209

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 109 V------PFHFWFPEVLQGSPLITGLLLSTLMKFPPITL------LFMTSPSLNP--TLLTTMAILSLALGGWMGLNQTQ 174
Cdd:PRK06277  210 LygsglpPFHTIKSDIYAKAKPFGSALLQTFSKFVLVALmlvifkLFGGLSYFPSaqGVLIALSVLAMVFGVVMALLQTD 289

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 175 IRKILAFSSISHLGWMAAIIVYSPKLTL-------LNFYLYTlmtATVFLSLNSI----KALKLSTLMTTWTKTPALTTM 243
Cdd:PRK06277  290 YKRLLAYHAISQGGYVAAGLALGTPLGIvagifhaINHVIYK---SALFLGAGIVsyrtKTSNLRKLGGLLPVMPVVAFM 366

                         250       260
                  ....*....|....*....|....*
gi 2220543591 244 LLLVLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:PRK06277  367 VLCAKLAISGVPPFNGFQSKLMLAQ 391
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-279 3.22e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 42.50  E-value: 3.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591   2 NPQAKLVFTVSLLLGTTITISSNHWVLaWTGLEINTLAILPLISKSHHPRAIEAATKYFLVqATASALVLF--ASMTNAW 79
Cdd:PRK06589  115 SSRFLFFFNLTILIGVLIALSSDLFTM-FVCYELLTISTAFLIGHTRNNISLSGGYKYLKI-LMISALLLFlpAVILIYT 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  80 ATGQWDITQ---LTHPTSSLILTSALAM--KLGLVPFHFWFPEVLQGSPLITGLLLSTLM----KFPPITLLFMTSPSLN 150
Cdd:PRK06589  193 KTGNLDFVSgglFSKNQSIILLLMFIYGiaKTAIFPVHSWLPAAMVAHYPVSALLHAVIVvktgLFCIYKILLYIFGLSY 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 151 PTLLTTM-------AILSLALGGWMGLNQTQIRKILAFSSISHLGW--MAAIIVYSPKLTLLNFYLYT--LMTATVFLSL 219
Cdd:PRK06589  273 LQRIFAEfnwlifiPIVSIFYSSLKALKTDNIKKILAYSTISQLSLalLSAFILTPKALGAAILHLVShsFAKICLFYSM 352

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2220543591 220 NSIKALK----LSTLMTTWTKTPALTTMLLLVLLSLAGLPPLTGFLPKWLIIQELTKQDMAVTA 279
Cdd:PRK06589  353 GSIYSLKkedqVDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLS 416
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 55-188 6.31e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 41.64  E-value: 6.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  55 AATKYFLVQATASALVLFASMTNAWATGQWDITQLTHPTSSLILT-----SALAMKLGLVPFHFWFPEVLQGSP-----L 124
Cdd:PRK08667  163 AGIFYFVMTQLSTVFLMLGIIVLFIQTGSFELSPLGASAGILSLVflllfLGFGIKAGIIPFHKWLPYAHPASPsnvsaL 242

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2220543591 125 ITGLLLST----LMKFppitLLFMTSPSLN-PTLLTTMAILSLALGGWMGLNQTQIRKILAFSSISHLG 188
Cdd:PRK08667  243 MSGVMLKVavygLVRF----LMDVLSPELWwGVLILLAGSISALLGVIYALKEHDLKGLLAYSSIENIG 307
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-267 6.33e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 41.26  E-value: 6.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  33 LEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWATGQWDITQL-----------THPTSSLILTSA 101
Cdd:PRK12662  139 LEISSISSYVLVAMGRDKKALVAAFEYLIIGTIGATFYLIGIGFLYAITGTLNMGDMfliiqdlptnrAIQIGVLFIMVG 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 102 LAMKLGLVPFHFWFPEVLQGSPLITGLLLS----TLMKFPPITL--------LFMTSPSLNpTLLTTMAILSLALGGWMG 169
Cdd:PRK12662  219 LFIKAALFPFHKWLIQAYSEAPSFISVFFSgtstKVMIYLIIRIvydvfkanFVFTTLPFN-NVFMILAALAIVFGSVLA 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 170 LNQTQIRKILAFSSISHLGWMAAIIVYSPKLTLLNFYLY----TLMTATVFLSLNSIK----ALKLSTLMTTWTKTPALT 241
Cdd:PRK12662  298 ILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYivnhSIVKSALFMVSGSISyhfgTTKLEDCLNLWKSMPKIT 377

                         250       260
                  ....*....|....*....|....*.
gi 2220543591 242 TMLLLVLLSLAGLPPLTGFLPKWLII 267
Cdd:PRK12662  378 LAFVLLSLSLIGMPPTSGFVAKWYIL 403
PRK12646 PRK12646
DUF4040 family protein;
110-194 8.07e-04

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 41.28  E-value: 8.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 110 PFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPT-----LLTTMAILSLALGGWMGLNQTQIRKILAFSSI 184
Cdd:PRK12646  228 PFHIWLPRAMAAPTPVSAYLHSATMVKAGIFLLFRFTPLLGLSnmyiyIVTFVGLITMLFGSITALKQWDLKGILAYSTI 307

                          90
                  ....*....|
gi 2220543591 185 SHLGWMAAII 194
Cdd:PRK12646  308 SQLGMIMAMV 317
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 105-222 1.19e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 40.71  E-value: 1.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 105 KLGLvpfHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPTLLTTMAI-----LSLALGGWMGLNQTQIRKIL 179
Cdd:MTH00032  241 QLGL---HTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRSFPLFEKAPLTLLIItifgaLTAFFAATVGLVQNDLKKVI 317

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2220543591 180 AFSSISHLGWMAAIIVY--SPKLTLLNFYLYTLMTATVFLSLNSI 222
Cdd:MTH00032  318 AYSTCSQLGYMVLIIGIegSHNVGLFHLVNHAFFKALLFLSAGSV 362
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 101-195 1.19e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 40.68  E-value: 1.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 101 ALAMKLGLVPFHFWFPEVLQGSPLITGLLLS-TLMKFPPITLLFMTSP-------SLNPTLLtTMAILSLALGGWMGLNQ 172
Cdd:MTH00226  239 AMAVKIPIFPFHIWLPKAHVEAPVAGSVLLAgILLKLGGYGLVRLSWPilplgaqNLAPAVI-AMGIVGIVYGSFATCRQ 317

                          90       100
                  ....*....|....*....|...
gi 2220543591 173 TQIRKILAFSSISHLGWMAAIIV 195
Cdd:MTH00226  318 IDVKRLVAYSSVAHMGLVSITLV 340
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 32-190 1.73e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 39.95  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  32 GLEINTLAILPLISKSHHPRAIEAATKYFLVQATASALVLFA-SMTNAwATGQWDITQL----------THPTSSLILTS 100
Cdd:PRK12665  139 GFEILLVASYVLLTLGATAARVRAGVTYVMVSMVSSLLFLIGiALVYA-ATGTLNMADLavrldelpsgTRTALFAVLLV 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 101 ALAMKLGLVPFHFWFPEVLQGSP-LITGLLLSTLMK---FPPI---TLLFmTSPSLNpTLLTTMAILSLALGGWMGLNQT 173
Cdd:PRK12665  218 AFGIKAAVFPLSFWLPDSYPTAPaPVTAVFAGLLTKvgvYAIIrthTLLF-PGGGLD-TLLMVVALLTMVVGILGAIAQS 295

                         170
                  ....*....|....*..
gi 2220543591 174 QIRKILAFSSISHLGWM 190
Cdd:PRK12665  296 DIKRLLSFTLVSHIGYM 312
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 101-188 1.78e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 40.05  E-value: 1.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 101 ALAMKLGLVPFHFWFPEV-----LQGSPLITGLLLST----LMKFpPITLLFMTSPSLNPtLLTTMAILSLALGGWMGLN 171
Cdd:MTH00204  218 SLAVKIPQIPFHIWLPQAhveapVAGSVILAGILLKLggygFLRF-SWPLFPAASEYFAP-LIVMLSVIAVIYGSLTTCR 295

                          90
                  ....*....|....*..
gi 2220543591 172 QTQIRKILAFSSISHLG 188
Cdd:MTH00204  296 QVDFKRLIAYSSVAHMG 312
PRK08168 PRK08168
NADH-quinone oxidoreductase subunit L;
13-190 1.85e-03

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236171 [Multi-domain]  Cd Length: 516  Bit Score: 40.07  E-value: 1.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  13 LLLGTTITISSNHWVL---AW--TGLEINTLailpLISKSHHPRAIEAATKYFLVQATASALVLFASMTNAWATGQWDIT 87
Cdd:PRK08168  109 VLAAVHLLVLSDHLLVliaAWaaISLALHRL----LCFYPDRPFARLAAHKKFIADRLAELLLLAAAALAYLEVGSLSLS 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591  88 QL-----THPTSS------LILTSALAMKLGLVPFHFWFPEVLQGSPLITGLLLS--------TLMKFPPitlLFMTSPS 148
Cdd:PRK08168  185 ALwahlaAQGASPslqaaaLLLVLAVILKTAQLPVHGWLIQVMEAPTPVSALLHAgvvnlggfVLIRFAP---LLEQAPP 261

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2220543591 149 LNpTLLTTMAILSLALGGWMGLNQTQIRKILAFSSISHLGWM 190
Cdd:PRK08168  262 AR-WLLVLVGLATAVLAGLVMLTRISIKVRLAWSTVAQMGFM 302
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 109-282 2.23e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 39.90  E-value: 2.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 109 VPFHFWFPEVLQGSPLITGLLLSTLMKFPPITLLFMTSPSLNPT-----LLTTMAILSLALGGWMGLNQTQIRKILAFSS 183
Cdd:PRK12647  212 FPFHFWLPNAMEAPTPVSAYLHSATMVKAGIYLLARLNPVLGGTplwqtILPLFGGLTMLTGALLAVRQTDLKLILAYST 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2220543591 184 ISHLGWMAAIIVYSPKLTLLNFYLY----TLMTATVFLSLNSIK-------ALKLSTLmttWTKTPALTTMLLLVLLSLA 252
Cdd:PRK12647  292 VSALGTLVMLLGLGSELAIKAAVLFlvahSLYKGALFMVAGIIDhetgtrdITKLGGL---RRAMPITAAAALLAALSMA 368

                         170       180       190
                  ....*....|....*....|....*....|
gi 2220543591 253 GLPPLTGFLPKWLIIQELTKQDMAVTATTI 282
Cdd:PRK12647  369 GLPPLFGFLAKELIYEALLEAPLWSLILTV 398
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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