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Conserved domains on  [gi|2267399874|gb|UTE83109|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Propithecus deckenii coronatus]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-172 6.91e-65

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 196.56  E-value: 6.91e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874   1 MAYVVFMLSVGFVLGFMSFSSKPSPIYGGVGLIVSGAVGCGMVMNFGGSFVGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874  81 TWGSSVVIWGALLLGLMM-ELLMVMLMVGYEGLGGVGFVGLENWVMFVDKEVGVVREDSLGVTALYGKTSWFVMVAAWSL 159
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMeLLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|...
gi 2267399874 160 LVSVLIVIEIIRG 172
Cdd:MTH00109  162 FIGVFVIIEITRG 174
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-172 6.91e-65

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 196.56  E-value: 6.91e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874   1 MAYVVFMLSVGFVLGFMSFSSKPSPIYGGVGLIVSGAVGCGMVMNFGGSFVGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874  81 TWGSSVVIWGALLLGLMM-ELLMVMLMVGYEGLGGVGFVGLENWVMFVDKEVGVVREDSLGVTALYGKTSWFVMVAAWSL 159
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMeLLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|...
gi 2267399874 160 LVSVLIVIEIIRG 172
Cdd:MTH00109  162 FIGVFVIIEITRG 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
21-169 1.78e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 50.58  E-value: 1.78e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874  21 SKPSPIYGGVGLIVSGAVGCGMVMNFGGSFVGLMVFLIYLGGMLVVFGYTTAM-ATEEYPETWGSSVVIWGALLLGLMME 99
Cdd:pfam00499   5 TSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGLLLLA 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874 100 LLMVMLMVGYEGLGGVGFvglenwvmfvdkEVGVVREDSLGVtALYGKTSWFVMVAAWSLLVSVLIVIEI 169
Cdd:pfam00499  85 LLLLVLLSASLTPAAAAA------------APDVGNIEAIGE-LLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-172 6.91e-65

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 196.56  E-value: 6.91e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874   1 MAYVVFMLSVGFVLGFMSFSSKPSPIYGGVGLIVSGAVGCGMVMNFGGSFVGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874  81 TWGSSVVIWGALLLGLMM-ELLMVMLMVGYEGLGGVGFVGLENWVMFVDKEVGVVREDSLGVTALYGKTSWFVMVAAWSL 159
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMeLLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|...
gi 2267399874 160 LVSVLIVIEIIRG 172
Cdd:MTH00109  162 FIGVFVIIEITRG 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 1.43e-33

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 116.78  E-value: 1.43e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874   1 MAYVVFMLSVGFVLGFMSFSSKPSPIYGGVGLIVSGAVGCGMVMNFGGSFVGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874  81 TWGS-SVVIWGALLLGLMMELLMVMLMVGYEGLggvgfvglenWVMFVD-KEVGVVREDSLGVTALYGKTSWFVMVAAWS 158
Cdd:MTH00138   81 SWGSwSVLGYVVGYLVGVVLAAGLFWGGWYEGS----------WVVVDElKEFSVLRGDVGGVALMYSSGGGMLVICAWV 150

                         170
                  ....*....|....
gi 2267399874 159 LLVSVLIVIEIIRG 172
Cdd:MTH00138  151 LLLTLFVVLELTRG 164
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 1.50e-30

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 108.78  E-value: 1.50e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874   1 MAYVVFMLSVGFVLGFMSFSSKPSPIYGGVGLIVSGAVGCGMVMNFGGSFVGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874  81 TWGSSVVIWgalllglMMELLMVMLMVGYegLGGVGFVGLENWVMFVDKEVGVVREDSLGVTALYGKTSWFVMVAAWSLL 160
Cdd:MTH00065   81 AWGSWSVLV-------YVLFYLLLLIVGY--ILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLL 151

                         170
                  ....*....|..
gi 2267399874 161 VSVLIVIEIIRG 172
Cdd:MTH00065  152 LTLFVVLEVTRG 163
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.01e-23

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 91.35  E-value: 1.01e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874   1 MAYVVFMLSVGFVLGFMSFSSKPSPIYGGVGLIVSGAVGCGMVMNFGGSFVGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874  81 TWGSSVVIWGALLLGLMMELLMVMLMVGYEGLGGVGfvglenwVMFVDKEVGVVREDSLGVTALYGKTSWFVMVAAWSLL 160
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGV-------VTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLL 153

                         170
                  ....*....|..
gi 2267399874 161 VSVLIVIEIIRG 172
Cdd:MTH00115  154 LTLFVVLELVRG 165
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 7.29e-15

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 68.09  E-value: 7.29e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874   1 MAYVVFMLSVGFVLGFMSFSSKPSPIYGGVGLIVSGAVGCGMVMNFGGSFVGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874  81 TWGSSVVIWGALLLGLMMELLMVMLMVGYEGLGGVGFVGLENWVMfvdkevgvvredsLGVTALYGKTSWFVMVAAWSLL 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLDL-------------SGVSDLYSRGFFLLLLGGVVLF 147

                         170
                  ....*....|..
gi 2267399874 161 VSVLIVIEIIRG 172
Cdd:MTH00214  148 LVLFVVLELVRG 159
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
21-169 1.78e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 50.58  E-value: 1.78e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874  21 SKPSPIYGGVGLIVSGAVGCGMVMNFGGSFVGLMVFLIYLGGMLVVFGYTTAM-ATEEYPETWGSSVVIWGALLLGLMME 99
Cdd:pfam00499   5 TSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGLLLLA 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874 100 LLMVMLMVGYEGLGGVGFvglenwvmfvdkEVGVVREDSLGVtALYGKTSWFVMVAAWSLLVSVLIVIEI 169
Cdd:pfam00499  85 LLLLVLLSASLTPAAAAA------------APDVGNIEAIGE-LLFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 24-172 2.00e-08

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 50.67  E-value: 2.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267399874  24 SPIYGGVGLIVSGAVGCGMVMNFGGSFVGLMVFLIYLGGMLVVFGYTTAMATEEYPETWGSSVVIwgalllglmmellmV 103
Cdd:MTH00045   22 SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSVSNLGEVL--------------V 87

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2267399874 104 MLMVGYEGLGGVGFVGLENWVMFVDKevgVVREDSLGVTALYGKTSWFVMVAAWSLLVSVLIVIEIIRG 172
Cdd:MTH00045   88 LSLLLSLWVFISFDNFLELSNNNWSL---VSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFG 153
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 7-78 2.35e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 39.60  E-value: 2.35e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2267399874   7 MLSVGFVLGFMsFSSKPSPIYGGVGLIVSGAVGCGMVMNFGGSFVGLMVFLIYLGGMLVVFGYTTAMATEEY 78
Cdd:MTH00212    6 LLSLLLLLMLL-FPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALSPNEH 76
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 4-74 1.16e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 37.56  E-value: 1.16e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2267399874   4 VVFMLSVGFVLGFMSFSSKpSPIYGGVGLIVSGAVGCGMVMNFGGSFVGLMVFLIYLGGMLVVFGYTTAMA 74
Cdd:MTH00152    3 LMILLSVCFSLFLLLPLSK-QPLSLGLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLS 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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