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Conserved domains on  [gi|2289440352|gb|UVJ68813|]
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thyrotropin, partial [Hipposideros cf. ruber ZMMU S-192897]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GHB_like super family cl21545
Glycoprotein hormone beta chain homologues; This family of cystine-knot hormones includes the ...
 1-30 6.72e-05

Glycoprotein hormone beta chain homologues; This family of cystine-knot hormones includes the beta chains of gonadotropins, thyrotropins, follitropins, choriogonadotropins and more. The members are reproductive hormones that consist of two glycosylated chains (alpha and beta), which form a tightly bound dimer.


The actual alignment was detected with superfamily member smart00068:

Pssm-ID: 473907  Cd Length: 107  Bit Score: 35.72  E-value: 6.72e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 2289440352    1 DINGKLFLPkyALSQDVCTYGDFTYKTVEI 30
Cdd:smart00068  38 DPVYKSPLP--PLPQRVCTYRELRYETVRL 65
 
Name Accession Description Interval E-value
GHB smart00068
Glycoprotein hormone beta chain homologues; Also called gonadotropins. Glycoprotein hormones ...
 1-30 6.72e-05

Glycoprotein hormone beta chain homologues; Also called gonadotropins. Glycoprotein hormones consist of two glycosylated chains (alpha and beta) of similar topology.


Pssm-ID: 214502  Cd Length: 107  Bit Score: 35.72  E-value: 6.72e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 2289440352    1 DINGKLFLPkyALSQDVCTYGDFTYKTVEI 30
Cdd:smart00068  38 DPVYKSPLP--PLPQRVCTYRELRYETVRL 65
GHB_like cd00069
Glycoprotein hormone beta chain homologues; This family of cystine-knot hormones includes the ...
 1-30 7.08e-05

Glycoprotein hormone beta chain homologues; This family of cystine-knot hormones includes the beta chains of gonadotropins, thyrotropins, follitropins, choriogonadotropins and more. The members are reproductive hormones that consist of two glycosylated chains (alpha and beta), which form a tightly bound dimer.


Pssm-ID: 200450  Cd Length: 96  Bit Score: 35.34  E-value: 7.08e-05
                         10        20        30
                 ....*....|....*....|....*....|
gi 2289440352  1 DINGKLFLPKyALSQDVCTYGDFTYKTVEI 30
Cdd:cd00069   34 DPVYKSPPYK-PSHQPVCTYDEWRYETVRL 62
 
Name Accession Description Interval E-value
GHB smart00068
Glycoprotein hormone beta chain homologues; Also called gonadotropins. Glycoprotein hormones ...
 1-30 6.72e-05

Glycoprotein hormone beta chain homologues; Also called gonadotropins. Glycoprotein hormones consist of two glycosylated chains (alpha and beta) of similar topology.


Pssm-ID: 214502  Cd Length: 107  Bit Score: 35.72  E-value: 6.72e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 2289440352    1 DINGKLFLPkyALSQDVCTYGDFTYKTVEI 30
Cdd:smart00068  38 DPVYKSPLP--PLPQRVCTYRELRYETVRL 65
GHB_like cd00069
Glycoprotein hormone beta chain homologues; This family of cystine-knot hormones includes the ...
 1-30 7.08e-05

Glycoprotein hormone beta chain homologues; This family of cystine-knot hormones includes the beta chains of gonadotropins, thyrotropins, follitropins, choriogonadotropins and more. The members are reproductive hormones that consist of two glycosylated chains (alpha and beta), which form a tightly bound dimer.


Pssm-ID: 200450  Cd Length: 96  Bit Score: 35.34  E-value: 7.08e-05
                         10        20        30
                 ....*....|....*....|....*....|
gi 2289440352  1 DINGKLFLPKyALSQDVCTYGDFTYKTVEI 30
Cdd:cd00069   34 DPVYKSPPYK-PSHQPVCTYDEWRYETVRL 62
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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