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Conserved domains on  [gi|2311335070|gb|UXP34484|]
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wolbachia surface protein, partial [Sitophilus oryzae]

Protein Classification

porin family protein( domain architecture ID 229388)

porin family protein is a member of a large superfamily consisting of classical (gram-negative ) porins which are non-specific channels for small hydrophillic molecules, maltoporin-like channels which have specificities for various sugars, and ligand-gated protein channels which cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OM_channels super family cl21487
Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in ...
 5-197 5.31e-52

Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20), which associate as trimers. Maltoporin-like channels have specificities for various sugars and form 18 beta-stranded barrels (18,22), which associate as trimers. Ligand-gated protein channels cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force and they form monomeric, (22,24) barrels. The 150-200 N-terminal residues form a plug that blocks the channel from the periplasmic end.


The actual alignment was detected with superfamily member pfam01617:

Pssm-ID: 473880  Cd Length: 247  Bit Score: 167.26  E-value: 5.31e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2311335070   5 DEETSYYVRLQYNGEILPLYTKVDGIT-----NAAGKEKD---------------------SPLTRSFIAGGGAFGYKMD 58
Cdd:pfam01617   1 DGEGSFYISLKYNPSISHFGTFSAKETggttkGVFGLKKDwdgvsiskhanfdfsvpgysfKYENNLFTGFGGAIGYSMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2311335070  59 DIRVDVEGLYSQLAK--------------------DATVVSDNKA----ADSVTAFSGLVNVYYDIAIEDMPITPYIGVG 114
Cdd:pfam01617  81 GPRVELEGSYERFDVknqgnnykndahkyaaltrdAAITAADSKYvvlkNDGLTDISLMLNACYDIAHEGIPVSPYVCAG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2311335070 115 VGAAYISnpskadaVKEQKGFGFAYQAKAGVSYDVTPEIKLFAGARYFGSYGASFNKETVL-----------ATKEINVL 183
Cdd:pfam01617 161 VGADLIS-------VFGAINPKFSYQGKAGVSYPITPEISLFAGGHYHKVIGNEFDDIPTLhpstltgaaktTSASVTLD 233

                         250
                  ....*....|....
gi 2311335070 184 YSAVGAEAGVAFNF 197
Cdd:pfam01617 234 VAYFGAELGVRFNF 247
 
Name Accession Description Interval E-value
Surface_Ag_2 pfam01617
Surface antigen; This family includes a number of bacterial surface antigens expressed on the ...
 5-197 5.31e-52

Surface antigen; This family includes a number of bacterial surface antigens expressed on the surface of pathogens.


Pssm-ID: 366729  Cd Length: 247  Bit Score: 167.26  E-value: 5.31e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2311335070   5 DEETSYYVRLQYNGEILPLYTKVDGIT-----NAAGKEKD---------------------SPLTRSFIAGGGAFGYKMD 58
Cdd:pfam01617   1 DGEGSFYISLKYNPSISHFGTFSAKETggttkGVFGLKKDwdgvsiskhanfdfsvpgysfKYENNLFTGFGGAIGYSMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2311335070  59 DIRVDVEGLYSQLAK--------------------DATVVSDNKA----ADSVTAFSGLVNVYYDIAIEDMPITPYIGVG 114
Cdd:pfam01617  81 GPRVELEGSYERFDVknqgnnykndahkyaaltrdAAITAADSKYvvlkNDGLTDISLMLNACYDIAHEGIPVSPYVCAG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2311335070 115 VGAAYISnpskadaVKEQKGFGFAYQAKAGVSYDVTPEIKLFAGARYFGSYGASFNKETVL-----------ATKEINVL 183
Cdd:pfam01617 161 VGADLIS-------VFGAINPKFSYQGKAGVSYPITPEISLFAGGHYHKVIGNEFDDIPTLhpstltgaaktTSASVTLD 233

                         250
                  ....*....|....
gi 2311335070 184 YSAVGAEAGVAFNF 197
Cdd:pfam01617 234 VAYFGAELGVRFNF 247
LomR COG3637
Opacity protein LomR and related surface antigens [Cell wall/membrane/envelope biogenesis];
42-197 7.64e-10

Opacity protein LomR and related surface antigens [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442854 [Multi-domain]  Cd Length: 154  Bit Score: 54.98  E-value: 7.64e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2311335070  42 LTRSFIAGGGAFGYKMD----DIRVDVEGLYSQLAKDATVVSDNkaaDSVTAFSGLVNVYYDIaieDMPITPYIGVGVGA 117
Cdd:COG3637     4 LLLAALAAGVQAGYNFQfdnfVLGVEGDYSYSDIDGDSSGTTGS---GDLDYLSLRARAGYDF---NDRFLPYATAGVAY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2311335070 118 AYI--SNPSKADAVKEQKGFGFAYQAKAGVSYDVTPEIKLFAGARYFGsygasFNKETVLATKEINVLYSAVGAEAGVAF 195
Cdd:COG3637    78 ARVkvTGNTGSGTSGSDSDTRFGWTVGAGVEYALTDNWSLRLEYRYTD-----LGDADFDGGGSVDVDLDSHTVRVGLNY 152


                  ..
gi 2311335070 196 NF 197
Cdd:COG3637   153 RF 154
 
Name Accession Description Interval E-value
Surface_Ag_2 pfam01617
Surface antigen; This family includes a number of bacterial surface antigens expressed on the ...
 5-197 5.31e-52

Surface antigen; This family includes a number of bacterial surface antigens expressed on the surface of pathogens.


Pssm-ID: 366729  Cd Length: 247  Bit Score: 167.26  E-value: 5.31e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2311335070   5 DEETSYYVRLQYNGEILPLYTKVDGIT-----NAAGKEKD---------------------SPLTRSFIAGGGAFGYKMD 58
Cdd:pfam01617   1 DGEGSFYISLKYNPSISHFGTFSAKETggttkGVFGLKKDwdgvsiskhanfdfsvpgysfKYENNLFTGFGGAIGYSMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2311335070  59 DIRVDVEGLYSQLAK--------------------DATVVSDNKA----ADSVTAFSGLVNVYYDIAIEDMPITPYIGVG 114
Cdd:pfam01617  81 GPRVELEGSYERFDVknqgnnykndahkyaaltrdAAITAADSKYvvlkNDGLTDISLMLNACYDIAHEGIPVSPYVCAG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2311335070 115 VGAAYISnpskadaVKEQKGFGFAYQAKAGVSYDVTPEIKLFAGARYFGSYGASFNKETVL-----------ATKEINVL 183
Cdd:pfam01617 161 VGADLIS-------VFGAINPKFSYQGKAGVSYPITPEISLFAGGHYHKVIGNEFDDIPTLhpstltgaaktTSASVTLD 233

                         250
                  ....*....|....
gi 2311335070 184 YSAVGAEAGVAFNF 197
Cdd:pfam01617 234 VAYFGAELGVRFNF 247
LomR COG3637
Opacity protein LomR and related surface antigens [Cell wall/membrane/envelope biogenesis];
42-197 7.64e-10

Opacity protein LomR and related surface antigens [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442854 [Multi-domain]  Cd Length: 154  Bit Score: 54.98  E-value: 7.64e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2311335070  42 LTRSFIAGGGAFGYKMD----DIRVDVEGLYSQLAKDATVVSDNkaaDSVTAFSGLVNVYYDIaieDMPITPYIGVGVGA 117
Cdd:COG3637     4 LLLAALAAGVQAGYNFQfdnfVLGVEGDYSYSDIDGDSSGTTGS---GDLDYLSLRARAGYDF---NDRFLPYATAGVAY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2311335070 118 AYI--SNPSKADAVKEQKGFGFAYQAKAGVSYDVTPEIKLFAGARYFGsygasFNKETVLATKEINVLYSAVGAEAGVAF 195
Cdd:COG3637    78 ARVkvTGNTGSGTSGSDSDTRFGWTVGAGVEYALTDNWSLRLEYRYTD-----LGDADFDGGGSVDVDLDSHTVRVGLNY 152


                  ..
gi 2311335070 196 NF 197
Cdd:COG3637   153 RF 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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