NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2312612558|gb|UXQ87834|]
View 

NADH dehydrogenase subunit 2, partial (mitochondrion) [Challengerosergia talismani]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 20-324 2.00e-72

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 227.01  E-value: 2.00e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  20 SISSSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNSA----SFFLITSLLLK 95
Cdd:MTH00160   21 SISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLMLFnnisSMLINSSLLLK 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  96 AGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMtgsILLSALVGAIGGLNQTFLRKIMAYSSIN 175
Cdd:MTH00160  101 LGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIII---IILSAIIGAIGGLNQTSLRKILAYSSIN 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 176 HMSWMLSAIMLSESSWMVYFMVYSIVSSSLAFLFHSHQSFHISHIMNHSSHSQTMKILTFISLLSLGGLPPFTGFIAKWF 255
Cdd:MTH00160  178 HLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLPPFLGFLPKWI 257

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 256 IIQELAFNHMFITLLVLLSSALVTLFYYLRIAMTSMMLSSPKSKWMKSSKFNSSI-ITPFLIFVNSVGIF 324
Cdd:MTH00160  258 IIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSlILNFLSFISLFGLI 327
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 20-324 2.00e-72

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 227.01  E-value: 2.00e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  20 SISSSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNSA----SFFLITSLLLK 95
Cdd:MTH00160   21 SISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLMLFnnisSMLINSSLLLK 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  96 AGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMtgsILLSALVGAIGGLNQTFLRKIMAYSSIN 175
Cdd:MTH00160  101 LGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIII---IILSAIIGAIGGLNQTSLRKILAYSSIN 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 176 HMSWMLSAIMLSESSWMVYFMVYSIVSSSLAFLFHSHQSFHISHIMNHSSHSQTMKILTFISLLSLGGLPPFTGFIAKWF 255
Cdd:MTH00160  178 HLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLPPFLGFLPKWI 257

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 256 IIQELAFNHMFITLLVLLSSALVTLFYYLRIAMTSMMLSSPKSKWMKSSKFNSSI-ITPFLIFVNSVGIF 324
Cdd:MTH00160  258 IIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSlILNFLSFISLFGLI 327
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 21-286 4.21e-26

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 107.51  E-value: 4.21e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  21 ISSSSWFGAWVGLELNLLSFIPLIS-SKNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNSASF------------- 86
Cdd:COG1007   119 ASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLagiaaalaaggan 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  87 ---------FLITSLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSL-------ISYTISYSSSFLMTGSILL 150
Cdd:COG1007   199 spllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAAllrllveAFPGLAADWQLLLAVLAVL 278

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 151 SALVGAIGGLNQTFLRKIMAYSSINHMSWMLSAIM----LSESSWMVYFMVYSIvSSSLAFLF---HSHQSFHISHIMNH 223
Cdd:COG1007   279 SMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAagtpLGVSAALFYLLAYLF-MNLGAFAVillLSRKGGEAEEIEDL 357

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2312612558 224 SSHSQTMKILTF---ISLLSLGGLPPFTGFIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRI 286
Cdd:COG1007   358 AGLARRSPLLALamtIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-258 6.69e-26

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 104.32  E-value: 6.69e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  23 SSSWFGAWVGLELNLLSFIPLISS-KNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNSASF--------------- 86
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFdelskaltgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  87 ------FLITSLLLKAGAAPFHFWFPSVMEGLNWP-QAITLMTVQKIAP-----MSLISYTISYSSSFLMTGSILLSALV 154
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPvSALLAATLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 155 GAIGGLNQTFLRKIMAYSSINHMSWMLSAIML----SESSWMVYFMVYSIVSSSL-----AFLFHSHQSFHISHIMNHSS 225
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLflcagSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2312612558 226 HSQTMKILTFISLLSLGGLPPFTGFIAKWFIIQ 258
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 21-324 1.57e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 91.55  E-value: 1.57e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  21 ISSSSWFGAWVGLELNLLSFIPLIS-SKNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNSASF------------- 86
Cdd:TIGR01770 119 VSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFedlllflsngmln 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  87 ---------FLITSLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAP--------MSLISYTISYSSSFLMTGSIL 149
Cdd:TIGR01770 199 isllllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIfavflrlfLYILFGFSEAWQIFLAIIAFL 278

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 150 lSALVGAIGGLNQTFLRKIMAYSSINHMSWMLSAIMLSE----SSWMVYFMVYSIVSSSLAFLFHSHQSF------HISH 219
Cdd:TIGR01770 279 -SMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTlegiKAVLFYIFIYALMSLGAFGVLSLLRSYkdewieYISD 357

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 220 IMNHSSHSQTMKILTFISLLSLGGLPPFTGFIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRIAMtsMMLSSPKSK 299
Cdd:TIGR01770 358 FAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVK--VMYFDKPER 435

                         330       340
                  ....*....|....*....|....*...
gi 2312612558 300 WMKSSKFNSS---IITPFLIFVNSVGIF 324
Cdd:TIGR01770 436 RIPSNPQSKAqslLLSISALFILFLGLF 463
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 20-324 2.00e-72

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 227.01  E-value: 2.00e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  20 SISSSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNSA----SFFLITSLLLK 95
Cdd:MTH00160   21 SISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLMLFnnisSMLINSSLLLK 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  96 AGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMtgsILLSALVGAIGGLNQTFLRKIMAYSSIN 175
Cdd:MTH00160  101 LGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIII---IILSAIIGAIGGLNQTSLRKILAYSSIN 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 176 HMSWMLSAIMLSESSWMVYFMVYSIVSSSLAFLFHSHQSFHISHIMNHSSHSQTMKILTFISLLSLGGLPPFTGFIAKWF 255
Cdd:MTH00160  178 HLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLPPFLGFLPKWI 257

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 256 IIQELAFNHMFITLLVLLSSALVTLFYYLRIAMTSMMLSSPKSKWMKSSKFNSSI-ITPFLIFVNSVGIF 324
Cdd:MTH00160  258 IIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSlILNFLSFISLFGLI 327
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 21-312 1.61e-66

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 212.38  E-value: 1.61e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  21 ISSSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSA----------SLFFMSLNSASFFLIT 90
Cdd:MTH00112   21 ISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSttnawntgqwDITQLTNPTSCTLLTL 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  91 SLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMTGSILLSALVGAIGGLNQTFLRKIMA 170
Cdd:MTH00112  101 ALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLNQTQLRKIMA 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 171 YSSINHMSWMLSAIMLSESSWMVYFMVYSIVSSSLAFLFHSHQSFHISHIMNHSSHSQTMKILTFISLLSLGGLPPFTGF 250
Cdd:MTH00112  181 FSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAGLPPLTGF 260

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2312612558 251 IAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRIAMTSMMLSSPKS-----KWMKSSKFNSSIIT 312
Cdd:MTH00112  261 MPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTtnmmmKWRTKPKKNTLTAT 327
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 21-316 4.19e-61

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 198.53  E-value: 4.19e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  21 ISSSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLFFMSLN----------SASFFLIT 90
Cdd:MTH00105   21 MISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGqwtitkltnpTASTLMTI 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  91 SLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMTGSILLSALVGAIGGLNQTFLRKIMA 170
Cdd:MTH00105  101 ALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILSILIGGWGGLNQTQLRKILA 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 171 YSSINHMSWMLSAIMLSESSWMVYFMVYSIVSSSLAFLFHSHQSFHISHIMNHSSHSQTMKILTFISLLSLGGLPPFTGF 250
Cdd:MTH00105  181 YSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLSLGGLPPLTGF 260

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2312612558 251 IAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRIAMTSMMLSSP-----KSKWMKSSKFNSSIITPFLI 316
Cdd:MTH00105  261 MPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPstnnmKMKWQFENTKPMTLLPTLII 331
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 20-324 3.14e-58

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 190.91  E-value: 3.14e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  20 SISSSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNS----------ASFFLI 89
Cdd:MTH00041   20 VISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSwsingplntlSSIIIT 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  90 TSLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMTGSILLSALVGAIGGLNQTFLRKIM 169
Cdd:MTH00041  100 LALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGLNQTQTRKIL 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 170 AYSSINHMSWMLSAIMLSESSWMVYFMVYSIVSSSLAFLFHSHQSFHISHIMNHSSHSQTMKILTFISLLSLGGLPPFTG 249
Cdd:MTH00041  180 AFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLPPLTG 259

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2312612558 250 FIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRIAMTSMMLSSPKSKWMKSSKFNSSIITPFLIFVNSVGIF 324
Cdd:MTH00041  260 FLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVYGVILSILSSI 334
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 21-324 2.56e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 183.25  E-value: 2.56e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  21 ISSSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLFFMS---------LNSASFFLIT- 90
Cdd:MTH00200   21 FSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTsgqwgisemLGPLSETLILl 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  91 SLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMTGSILLSALVGAIGGLNQTFLRKIMA 170
Cdd:MTH00200  101 ALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLLSVLVGGWGGLNQTQLRKILA 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 171 YSSINHMSWMLSAIMLSESSWMVYFMVYSIVSSSLAFLFHSHQSFHISHIMNHSSHSQTMKILTFISLLSLGGLPPFTGF 250
Cdd:MTH00200  181 YSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLLGLTLLSLGGLPPLTGF 260

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2312612558 251 IAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRIAMTSMMLSSPKSKWMKSS---KFNSSIITPFLIFVNSVGIF 324
Cdd:MTH00200  261 FPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSwrtKSNSNLLVGLLLLLSILGLP 337
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 21-316 6.73e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 182.43  E-value: 6.73e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  21 ISSSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSA----------SLFFMSLNSASFFLIT 90
Cdd:MTH00070   21 LSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSStinawftgewTIMNMQTPLPTIMLTI 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  91 SLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMTGSILLSALVGAIGGLNQTFLRKIMA 170
Cdd:MTH00070  101 ALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLLSTLIGGWGGLNQTQLRKIMA 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 171 YSSINHMSWMLSAIMLSESSWMVYFMVYSIVSSSLAFLFHSHQSFHISHIMNHSSHSQTMKILTFISLLSLGGLPPFTGF 250
Cdd:MTH00070  181 YSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTLLSLGGLPPTTGF 260

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2312612558 251 IAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRIAMTSMMLSSPK---SKWMKSSKFNSSIITPFLI 316
Cdd:MTH00070  261 IPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNtsnSKLYWRFKNKTNNLLSLTI 329
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 20-295 4.60e-52

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 174.58  E-value: 4.60e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  20 SISSSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLFFMS----LNSASFFLITSLLLK 95
Cdd:MTH00011   22 ALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFpsllKNITALMLLVSLMLK 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  96 AGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMTGSILLSALVGAIGGLNQTFLRKIMAYSSIN 175
Cdd:MTH00011  102 LGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMNQTQLRPLLAYSSIG 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 176 HMSWMLSAIMLSESSWMVYFMVYSIVSSSLAFLFHSHQSFHISHIMNHSSHSQTMKILTFISLLSLGGLPPFTGFIAKWF 255
Cdd:MTH00011  182 HMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLPPFTGFMPKLM 261

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 2312612558 256 IIQELAFNHMFITLLVLLSSALVTLFYYLRIAMTSMMLSS 295
Cdd:MTH00011  262 AIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSP 301
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 22-296 6.76e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 174.61  E-value: 6.76e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  22 SSSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSAS----------LFFMSLNSASFFLITS 91
Cdd:MTH00135   22 ASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTtnawltgqwdIQQMSHPLPTTMITLA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  92 LLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMTGSiLLSALVGAIGGLNQTFLRKIMAY 171
Cdd:MTH00135  102 LALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLG-LTSTLVGGWGGLNQTQLRKILAY 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 172 SSINHMSWMLSAIMLSESSWMVYFMVYSIVSSSLAFLFHSHQSFHISHIMNHSSHSQTMKILTFISLLSLGGLPPFTGFI 251
Cdd:MTH00135  181 SSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGLPPLTGFM 260

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2312612558 252 AKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRIAMTSMMLSSP 296
Cdd:MTH00135  261 PKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISP 305
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 20-317 7.79e-51

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 171.22  E-value: 7.79e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  20 SISSSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNS--ASFFLITSLLLKAG 97
Cdd:MTH00144   20 SLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSwfSMSLLLLGLCLKLG 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  98 AAPFHFWFPSVMEGLNWPQAITLMTVQKIAPM-SLISYTISYSSSFLMTGSILLSALVGAIGGLNQTFLRKIMAYSSINH 176
Cdd:MTH00144  100 LFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLfLLSNFLDLYWLAYLLCVISVLSALVGSIGGLNQTQVRALLAYSSISH 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 177 MSWMLSAIMLSESSWMVYFMVYSIVSSSLAFLFHSHQSFHIShIMNHSSHSQTMKILTFISLLSLGGLPPFTGFIAKWFI 256
Cdd:MTH00144  180 TGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMK-DLGSLKPSYKTGLSIISLLLSLGGLPPFLGFCSKLLV 258

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2312612558 257 IQELAFNHMFITLLVLLSSALVTLFYYLRIaMTSMMLSSPKSKWMKSSKFNSSIITPFLIF 317
Cdd:MTH00144  259 LISSMESSPLLLILLLLLGSLISLFFYLSV-FFSSFLSSSKSKKSNSSKVLNSSIISLNLL 318
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 20-310 1.03e-44

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 155.22  E-value: 1.03e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  20 SISSSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNSASFF---LITSLLLKA 96
Cdd:MTH00197   14 SLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYLSLLSvvlVILGLLLKL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  97 GAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMTGsiLLSALVGAIGGLNQTFLRKIMAYSSINH 176
Cdd:MTH00197   94 GAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICS--VLSSLIGGIGGMNQSNIRQLLAYSSIGH 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 177 MSWMLSAIMLSESSWMVYFMVYSIVSSSLAFLFHSHQSFHISHIMNHSSHSQTMKILTFISLLSLGGLPPFTGFIAKWFI 256
Cdd:MTH00197  172 TGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGLPPLSGFFLKWLI 251

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2312612558 257 IQELAFNHMFITLLVLLSSALVTLFYYLRIAMTSMMLSSPKSKWMKSSKFNSSI 310
Cdd:MTH00197  252 LTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSG 305
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 21-286 4.21e-26

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 107.51  E-value: 4.21e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  21 ISSSSWFGAWVGLELNLLSFIPLIS-SKNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNSASF------------- 86
Cdd:COG1007   119 ASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLagiaaalaaggan 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  87 ---------FLITSLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSL-------ISYTISYSSSFLMTGSILL 150
Cdd:COG1007   199 spllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAAllrllveAFPGLAADWQLLLAVLAVL 278

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 151 SALVGAIGGLNQTFLRKIMAYSSINHMSWMLSAIM----LSESSWMVYFMVYSIvSSSLAFLF---HSHQSFHISHIMNH 223
Cdd:COG1007   279 SMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAagtpLGVSAALFYLLAYLF-MNLGAFAVillLSRKGGEAEEIEDL 357

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2312612558 224 SSHSQTMKILTF---ISLLSLGGLPPFTGFIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRI 286
Cdd:COG1007   358 AGLARRSPLLALamtIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-258 6.69e-26

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 104.32  E-value: 6.69e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  23 SSSWFGAWVGLELNLLSFIPLISS-KNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNSASF--------------- 86
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFdelskaltgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  87 ------FLITSLLLKAGAAPFHFWFPSVMEGLNWP-QAITLMTVQKIAP-----MSLISYTISYSSSFLMTGSILLSALV 154
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPvSALLAATLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 155 GAIGGLNQTFLRKIMAYSSINHMSWMLSAIML----SESSWMVYFMVYSIVSSSL-----AFLFHSHQSFHISHIMNHSS 225
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLflcagSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2312612558 226 HSQTMKILTFISLLSLGGLPPFTGFIAKWFIIQ 258
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 21-286 4.33e-25

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 103.57  E-value: 4.33e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  21 ISSSSWFGAWVGLELNLLSFIPLISSK-NNQYSSESALKYFLIQALGSSIIILSASLFF------------MSLNSASFF 87
Cdd:MTH00196   10 ISSSNWLSVYLAIELQTLSLFILIAQNrGSGYSAEAGLKYFVLGALSSGLFLFGCALLCgttgglhlsyinLVLNSGQSF 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  88 -----------LITSLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMTGsiLLSALVGA 156
Cdd:MTH00196   90 ssvsvpigyllIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGG--LFSLFVGA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 157 IGGLNQTFLRKIMAYSSINHMSWMLSAIML----SESSWMVYFMVYsIVSSSLAFLFHSHQSFHISHIMNHSSHSQTMKI 232
Cdd:MTH00196  168 IGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfeSIQASLVYLFIY-IIMSICVFSIILALNVYKNLIIEFSGLSRRLPI 246

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2312612558 233 LTF---ISLLSLGGLPPFTGFIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRI 286
Cdd:MTH00196  247 LAItlaLTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
21-297 2.26e-23

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 99.90  E-value: 2.26e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  21 ISSSSWFGAWVGLELNLLSFIPLIS-SKNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNSASF------------- 86
Cdd:PRK05777  120 VSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFagiakaladgsgn 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  87 ---------FLITSLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLI-------SYTISYSSSFLMTGSILL 150
Cdd:PRK05777  200 sllllfglvFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllvvaFGGLSEDWQQVLAIIAIA 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 151 SALVGAIGGLNQTFLRKIMAYSSINHMSWMLSAIM----LSESSWMVYFMVYSIVS-SSLAFLFH-SHQSFHISHIMNHS 224
Cdd:PRK05777  280 SMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAagtaEGYSAVLFYLLAYLFMTlGAFGVISLlRRKGGEAESISDFA 359

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2312612558 225 SHSQTMKILTF---ISLLSLGGLPPFTGFIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRIaMTSMMLSSPK 297
Cdd:PRK05777  360 GLSKRSPLLAAvmtIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV-IKLMYFDEPP 434
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 21-257 5.64e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 95.85  E-value: 5.64e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  21 ISSSSWFGAWVGLELNLLS-FIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLF--------FMSLNSASF----- 86
Cdd:MTH00199  114 VSSINWLSIYLAIELQTLTlFILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLygltgetsIQGINSILTgdvgk 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  87 FLIT-SLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMtgSILLSALVGAIGGLNQTFL 165
Cdd:MTH00199  194 ILITiSLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLI--CAVLSIIYGAIGALNQTKI 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 166 RKIMAYSSINHMSWMLSAIMLSESS-------WMVYFMVYSIVSSSLAFLFHSHQSFhISHIMNHSSHSQTMKILTFISL 238
Cdd:MTH00199  272 KRLLAYSGIGHMGFILFGVAIGSFEsiqasliYMIIYVIMSICSFSIILSLKLTKGL-IVEVSGLSRKNPVIALTLALTF 350

                         250
                  ....*....|....*....
gi 2312612558 239 LSLGGLPPFTGFIAKWFII 257
Cdd:MTH00199  351 LSIAGIPPLAGFLSKWLIL 369
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 21-324 1.57e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 91.55  E-value: 1.57e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  21 ISSSSWFGAWVGLELNLLSFIPLIS-SKNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNSASF------------- 86
Cdd:TIGR01770 119 VSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFedlllflsngmln 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  87 ---------FLITSLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAP--------MSLISYTISYSSSFLMTGSIL 149
Cdd:TIGR01770 199 isllllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIfavflrlfLYILFGFSEAWQIFLAIIAFL 278

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 150 lSALVGAIGGLNQTFLRKIMAYSSINHMSWMLSAIMLSE----SSWMVYFMVYSIVSSSLAFLFHSHQSF------HISH 219
Cdd:TIGR01770 279 -SMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTlegiKAVLFYIFIYALMSLGAFGVLSLLRSYkdewieYISD 357

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 220 IMNHSSHSQTMKILTFISLLSLGGLPPFTGFIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRIAMtsMMLSSPKSK 299
Cdd:TIGR01770 358 FAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVK--VMYFDKPER 435

                         330       340
                  ....*....|....*....|....*...
gi 2312612558 300 WMKSSKFNSS---IITPFLIFVNSVGIF 324
Cdd:TIGR01770 436 RIPSNPQSKAqslLLSISALFILFLGLF 463
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 30-286 5.27e-17

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 80.96  E-value: 5.27e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  30 WVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLFFMS--------------------LNSASFFLI 89
Cdd:COG0651   133 FVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGAtgtlnmadlaarlaeldpglLLAAFALLL 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  90 TSLLLKAGAAPFHFWFPSVMeglnwPQAIT--------LMTvqKIAPMSLI--SYTISYSSSFLMTGSILL-----SALV 154
Cdd:COG0651   213 VGFGIKAALFPLHFWLPDAY-----PAAPSpvsallsgLLT--KVGVYAILrvLTLLFGADPALFLGTLLLvlgllTMLV 285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 155 GAIGGLNQTFLRKIMAYSSINHMSWMLSAIMLSES---SWMVYFMVYSIVSSSLAFL-----FHSHQSFHISHIMNHSSH 226
Cdd:COG0651   286 GALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPlglAGALFHLLNHALAKALLFLaagaiERATGTRDLDKLGGLGKR 365

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 227 SQTMKILTFISLLSLGGLPPFTGFIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRI 286
Cdd:COG0651   366 MPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 21-289 3.12e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 70.27  E-value: 3.12e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  21 ISSSSWFGAWVGLELNLLSFIPLISSKNNQYSS---------ESALKYFLIQALGSSIIILSASLFF------------- 78
Cdd:MTH00198  205 IESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFgftgnegmlgtil 284

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  79 --------MSLNSASF---FLITSLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMTGS 147
Cdd:MTH00198  285 satlettnIELRQGSLgylFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKLLLSVAI 364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 148 IllSALVGAIGGLNQTFLRKIMAYSSINHMSWMLSAIMLS-----ESSWMvyFMVYSIVSSSLAFLF------------- 209
Cdd:MTH00198  365 I--SLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGtyeslQASWT--YAVTYLVSALASFTVictleefgtrtpt 440

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 210 ----HSHQSFH--ISHIMNHSSHSQTMKILTF---ISLLSLGGLPPFTGFIAKWFIIQ---ELAFNH----MFITLLVLL 273
Cdd:MTH00198  441 srqrDGSFGNYnlVRRLVDLTILSRGQPYIAFslaIVFLSLAGIPPLLGFLGKWFILVgsiKIAFSSslsiYYLVALFAI 520

                         330
                  ....*....|....*.
gi 2312612558 274 SSALVTLFYYLRIAMT 289
Cdd:MTH00198  521 ICTCISAFYYIRIVAT 536
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 27-286 1.30e-12

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 67.98  E-value: 1.30e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  27 FGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLFFMS------------------LNSASFFL 88
Cdd:PRK08375  129 FNLFVFLEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVtgtlnmadlagalaenptVVTAFGFV 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  89 ITSLLLKAGAAPFHFWFPSVMEglNWPQAITLM---TVQKIAPMSLISYTISYSSSFLMTGSILLSAL---------VGA 156
Cdd:PRK08375  209 LLALALKAAVFPLHTWLPRAYP--AAPPVVTALlsgLVTKVAVYALIRIYFTVFGGDFRFALGLGWLLavlallsmlVGS 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 157 IGGLNQTFLRKIMAYSSINHMSWMLSAIMLSESSWM----VYFMVYSIVSSSLAF----LFHSHQSFHISHIMNHSSHSQ 228
Cdd:PRK08375  287 LAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALaaglLHLLHHALMKGALFLaagaIEVTYGTRRLSELSGLGRRMP 366

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2312612558 229 TMKILTFISLLSLGGLPPFTGFIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRI 286
Cdd:PRK08375  367 LTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRI 424
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
47-293 3.26e-09

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 57.75  E-value: 3.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  47 KNNQYSSESALKYFLIQALGSSIIILSASLFF-MS-------------LNSASFFLITSLLL-------KAGAAPFHFWF 105
Cdd:PRK02504  154 KRDPRSNEAALKYLLIGAASSAIFLYGSSLLYgLSggstqlsaialalITSPSLGLALALVFviagiafKISAVPFHQWT 233

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 106 PSVMEGLNWPQAITLMTVQKIAPMSLISYTISYSSS-------FLMTGSILLSALVGAIGGLNQTFLRKIMAYSSINHMS 178
Cdd:PRK02504  234 PDVYEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFPsfdeqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAG 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 179 W-MLSAIMLSES--SWMVYFMvysivsssLAFLFHSHQSFH----------ISHIMNHSSHSQTMKILTF---ISLLSLG 242
Cdd:PRK02504  314 FvMIGLVAGTEAgyASMVFYL--------LAYLFMNLGAFAcvilfslrtgTDQISDYAGLYQKDPLLTLglsLCLLSLG 385

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2312612558 243 GLPPFTGFIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRIamTSMML 293
Cdd:PRK02504  386 GIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRV--IKMMV 434
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 27-324 5.09e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 57.03  E-value: 5.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  27 FGAWVGLELNLLSFIPLISSKNNQY-SSESALKYFLIQALGSSIIILSASLFF--------------MSLN------SAS 85
Cdd:PRK08376  144 FNFFVFLEIMSIASYALVAFRNDTWeAIEAGIKYMFVGSLASSMVLLGIALLYgqygtlnmaylavkMSENptvvakIAL 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  86 FFLITSLLLKAGAAPFHFWFPSVMEGLnwPQAIT-LMTVQKIApmSLISYTISYSSSFLMTGSIL-----------LSAL 153
Cdd:PRK08376  224 ALFIAGLAMKSGAVPVHMWLPDAYPAA--PSSISaMLLVIKQA--GLYALARVLFSIYGPAINLAtvgwviiilgcLTMF 299

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 154 VGAIGGLNQTFLRKIMAYSSINHMSWMLSAIMLSESSWMVYFM-----------VYSIVSSSL--AFLFHSHQS-FHISH 219
Cdd:PRK08376  300 VGVAMAVVQKDVKRLLAYHSVSQIGYMLLGLGVGLAALGDPAMasygeialaggIYHIVNHALykALLFLTAGAvIYETG 379

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 220 IMNHSSHS---QTMKILTF---ISLLSLGGLPPFTGFIAKWFIIQELAFNHMFITlLVLLSSALVTLFYYLRIaMTSMML 293
Cdd:PRK08376  380 TRNLNELGglaRTMPKTTIaflIGAAAIVGLPPFNGFASKWLIYESSALFNPILG-VIAMIGSVLTLASFVKV-FHTAFF 457

                         330       340       350
                  ....*....|....*....|....*....|.
gi 2312612558 294 SSPKSKWMKSSKFNSSIITPFLIFVNSVGIF 324
Cdd:PRK08376  458 GPPSEKVMNVKEPPKPMLVPMLILAIAIIGM 488
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 149-324 2.28e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 48.81  E-value: 2.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 149 LLSALVGAIGGLNQTFLRKIMAYSSINHMSWMLSAIMLSESSWMVYFMVYSIVSS---SLAFL-----FHSHQSFHISHI 220
Cdd:PRK12667  303 AVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIINHAiakSLLFLasgvfIHAAGTRDIDEL 382

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 221 MNHSSHSQTMKILTFISLLSLGGLPPFTGFIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRiAMTSMMLSSPKSKW 300
Cdd:PRK12667  383 AGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFR-AWYSLFFGKPKSGE 461

                         170       180
                  ....*....|....*....|....
gi 2312612558 301 MKSSKFNSSIITPFLIFVNSVGIF 324
Cdd:PRK12667  462 EVEHKESPSMSVVILVLALAVLIL 485
ndhB CHL00049
NADH dehydrogenase subunit 2
 52-286 2.74e-06

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 48.85  E-value: 2.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  52 SSESALKYFLIQALGSSII-------------------ILSASLFFMSLNS-----ASFFLITSLLLKAGAAPFHFWFPS 107
Cdd:CHL00049  160 SNEATMKYLLMGGASSSILvygfswlyglsggeielqeIVNGLINTQMYNSpgisiALIFITVGIGFKLSLAPFHQWTPD 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 108 VMEGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMTGSIL-------LSALVGAIGGLNQTFLRKIMAYSSINHMSWM 180
Cdd:CHL00049  240 VYEGSPTPVVAFLSVTSKVAASALATRIFDIPFYFSSNEWHLlleilaiLSMILGNLIAITQTSMKRMLAYSSIGQIGYV 319

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 181 LSAIMLSESSW----MVYFMVYSIVSSSLAF----LFHSHQSfhISHIMNHSSHSQTMKILTF---ISLLSLGGLPPFTG 249
Cdd:CHL00049  320 IIGIIVGDSNDgyasMITYMLFYIFMNLGTFacivLFGLRTG--TDNIRDYAGLYTKDPFLALslaLCLLSLGGIPPLAG 397

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2312612558 250 FIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRI 286
Cdd:CHL00049  398 FFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 149-258 8.90e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 47.27  E-value: 8.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 149 LLSALVGAIGGLNQTFLRKIMAYSSINHMSWMLSAIMLSESSWM---VYFMVYSIVSSSLAFLF-----HSHQSFHISHI 220
Cdd:PRK12665  281 LLTMVVGILGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTVAGLsgaIYYVAHHITVQTTLFLVvglieRQAGSSSLRRL 360

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2312612558 221 MNHSSHSQTMKILTFISLLSLGGLPPFTGFIAKWFIIQ 258
Cdd:PRK12665  361 GGLAKASPLLAVLFFVPALNLGGIPPFSGFIGKVALLE 398
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
150-258 6.91e-05

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 44.17  E-value: 6.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 150 LSALVGAIGGLNQTFLRKIMAYSSINHMSWMLSAIMLSESSWM---VYFMVYSIVSSSLAFLFHSHQ-----SFHISHIM 221
Cdd:PRK12663  281 ITMVIGALGALAYKDIRRIAGYQVISSIGFILLGLALGTPAGIngaIFYLVHDMVVKTALFLIAGSLvrltgYRSLQYLG 360

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2312612558 222 NHSSHSQTMKILTFISLLSLGGLPPFTGFIAKWFIIQ 258
Cdd:PRK12663  361 GLYRKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQ 397
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 49-268 5.10e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 41.52  E-value: 5.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  49 NQYSSESALKYFLIQALGS---------------SIIILSASLFFMSLNSASFFLITSLLL------KAGAAPFHFWFPS 107
Cdd:PRK08668  142 KKESRKASLKYFVLSAIGAyamlyaifliyaktgTFDFADISQGLINDTSTGFALIVFLFLlafgvaKAGIFPLHVWAPD 221

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 108 VMEglNWPQAITLMTVQKIAPMSliSYTISYSSSFLMTGSIL---------------------LSALVGAIGGLNQTFLR 166
Cdd:PRK08668  222 AYS--EAPQSFSAVLSGQLSKLG--AYGFLLVLYVLPGTKLFsefgtyrgvplfnyilawlgnISIIVGTLMAILQEDIK 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 167 KIMAYSSINHMSWMLSAIMLSESSWMVYFMVYSI---VSSSLAFL-----FHSHQSFHISHiMNHSSHSQTMKILT-FIS 237
Cdd:PRK08668  298 KLIAYSSVANGGYILVGLGLGTSLGFAGGLFHVFnhaLFKGLFFLifaavIYRTGTTKISE-MGGLIEKMPFTFAMyLVA 376

                         250       260       270
                  ....*....|....*....|....*....|.
gi 2312612558 238 LLSLGGLPPFTGFIAKWFIIQELAFNHMFIT 268
Cdd:PRK08668  377 IISLAGIPPMSGFASKWLIFEALISKGMPIT 407
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 83-266 6.25e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 41.29  E-value: 6.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  83 SASFFLITSLLLKAGAA------PFHFWFPSVMEGlnwP-------QAITLMT--VQKIAPMSLISYTISYSSSFLMT-G 146
Cdd:COG1009   206 SSPLLTLILLLLLLGAFgksaqfPLHFWLPDAMEG---PtpvsallHAATMVKagVYLLARLSPLFALSPVWLTVVAIiG 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 147 SIllSALVGAIGGLNQTFLRKIMAYSSINHMSWMLSAIMLSE-SSWMVYFMVYSIVSSSLaflfhshqsFHISHIMNHSS 225
Cdd:COG1009   283 AI--TALFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVGAyVAALFHLLTHAFFKALL---------FLGAGSVIHAT 351

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2312612558 226 HSQTMK-------------ILTFISLLSLGGLPPFTGFIAKWFIIQELAFNHMF 266
Cdd:COG1009   352 GTRDIRkmgglrkkmpitaITFLIGALSLAGIPPFAGFFSKEAILEAALEAGGL 405
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 149-286 9.81e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 40.87  E-value: 9.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 149 LLSALVGAIGGLNQTFLRKIMAYSSINHMSWMLSAIMLSESSWMV----YFMVYSIVSSSLaFLFHSHQSFHI--SHIMN 222
Cdd:PRK12662  287 ALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAaavaYIVNHSIVKSAL-FMVSGSISYHFgtTKLED 365

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2312612558 223 HSSHSQTMKILTF---ISLLSLGGLPPFTGFIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRI 286
Cdd:PRK12662  366 CLNLWKSMPKITLafvLLSLSLIGMPPTSGFVAKWYILDAFIKSNAWIGLVVLLVGSGLSVIYVWKI 432
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 51-267 2.86e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 38.70  E-value: 2.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  51 YSSESALKYFLIQALGSSIIILSASLFFMSLnsasfflitSLLLKAGAAPFHFWFPSVMEGLNWPQAITLMTVQKIAPMS 130
Cdd:MTH00091   35 GSYSSLFNYFVLQESLGLLFLLFSFGYFQFL---------ILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 131 LISYTISYSSSFLMTGSILLSALVgaigGLNQTFLRKIMAYSSINHMSWMLSAIMLSESSWMVYFMVYSIVssslaflfh 210
Cdd:MTH00091  106 VLLQFFSKNFFFLLLFGLLICFFQ----MFLLKSYKNLLILSSTESFNWLILSFFFSFFNVFFLFFYYFLL--------- 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2312612558 211 shqsfhISHIMNHSSHSQTMKILTFISLLSLGGLPPFTGFIAKWFIIQELAFNHMFI 267
Cdd:MTH00091  173 ------MLFLIPKFNNVNKLNFVSWETLLVFMNLPFSVTFFVKIFSLSEILKVLGFF 223
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 70-261 2.94e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 39.35  E-value: 2.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  70 IILSASLFFMSLNSASF-FLITSLLLKAGAAPFHFWFPSV-MEGLNWPQAITLMTVQKIAPMS-------LISYTISYSS 140
Cdd:PRK08676  193 LAAHASLLSPSVLGASFlFIFIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGilrlsalLRQSGAAEQF 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 141 SFLMTGSILLSALVGAIGGLNQTFLRKIMAYSSINHMSWMLSAIMLSESS---WMVYFM-VYSIVSSSLAF----LFHSH 212
Cdd:PRK08676  273 SNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLalfWMLFHMlAHSLVKSGLFFsagiLHRQY 352

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2312612558 213 QSFHISHIMNHSSHSQTMKILTFISLLSLGGLPPFTGFIAKWFIIQELA 261
Cdd:PRK08676  353 RSDRFDRIFDVFRLQPVAAWGVILGSAAIIGMPPFPLFLSKFFILLQLG 401
PRK06525 PRK06525
hydrogenase 4 subunit D; Validated
 21-257 4.13e-03

hydrogenase 4 subunit D; Validated


Pssm-ID: 180606 [Multi-domain]  Cd Length: 479  Bit Score: 38.80  E-value: 4.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  21 ISSSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLFFMSLNSASFFLITSL-------- 92
Cdd:PRK06525  130 VYSSTLLGLLLFFEITGLCSWALISYYQSPKALRSALKALLITHIGSLGLYLAAATLFLQTGTFALSALSGLhgslkylv 209

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  93 ---LLKAGAA-----PFHFWFPSVMEGlnwP---------QAITLMTVQKIAPMSLISYTISYSSSFLMTGSILLSALVG 155
Cdd:PRK06525  210 flgILFAAWGksaqlPFYSWLPDAMEA---PtpasaylhaASMVKVGVYIFARAIQSMGPIPHVIGYVGAVMAIVTLLYG 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 156 AIGGLNQTFLRKIMAYSSINHMSWMLSAIMLSESSWMVYFM--VYSIVS----SSLAFLFHSHQSF-----HISHIMNHS 224
Cdd:PRK06525  287 FLMYLPQQDMKRLLAYSTITQLGYMFFGLSLAILGSRLALEgsIAYIFNhafaKSLFFLVAGALSYscgtrLLPRLRGVL 366

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2312612558 225 SHSQTMKILTFISLLSLGGLPPFTGFIAKWFII 257
Cdd:PRK06525  367 KKLPLVGVGFCVAALAITGVPPFNGFFSKFPIF 399
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 27-290 5.31e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 38.39  E-value: 5.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  27 FGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIILSASLFFM---SLNSA------------------- 84
Cdd:PRK07691  131 FNLFVFFEVMLMASYVLIVIGGTKIQLRESIKYVLINVVSSAFFVVAVAILYSvvgTLNMAdisvkiaelsagqtglitv 210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  85 -SFFLITSLLLKAGAAPFHFWFPSVMEGLnwPQAI--------TLMTVQKIAPM-SLISYTISYSSSFLMTGSILLSALV 154
Cdd:PRK07691  211 vAILFLFVFATKAGLFPLYFWLPGSYYAP--PIAIaalfgallTKVGVYAIARTfTLFFSHDTSFTHYLILILALLTIIF 288

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 155 GAIGGLNQTFLRKIMAYSSINHMSWMLSAI-MLSESSWM--VYFMVYSIVSSSLAFLF-----HSHQSFHISHIMNHSSH 226
Cdd:PRK07691  289 GVIGAVAYFDIKKIIIYNIMIAVGVILVGVaMMTESGMIgaIYYLIHDMIVKAALFLLigimiKITGTTDLKKMGGLIKR 368

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2312612558 227 SQTMKILTFISLLSLGGLPPFTGFIAKWFIIQELAFNHMFITLLVLLSSALVTLFYYLRIAMTS 290
Cdd:PRK07691  369 YPVLGWMFFIAALSLAGIPPLSGFYGKFFIVEGTFEAGFYVSGIIVLLSSLLVLYSVIKIFLKG 432
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 23-268 8.14e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 37.87  E-value: 8.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  23 SSSWFGAWVGLELNLLSFIPLISSKNNQYSSESALKYFLIQALGSSIIIL----------------SASLFFMSLNSASF 86
Cdd:PRK06589  135 SSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLpaviliytktgnldfvSGGLFSKNQSIILL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558  87 FLITSLLLKAGAAPFHFWFPSVM------EGLNWPQAITLMTVQKIAPMSLISYTISYSSSFLMTGSIL-----LSALVG 155
Cdd:PRK06589  215 LMFIYGIAKTAIFPVHSWLPAAMvahypvSALLHAVIVVKTGLFCIYKILLYIFGLSYLQRIFAEFNWLifipiVSIFYS 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312612558 156 AIGGLNQTFLRKIMAYSSINHMSW-MLSAIMLSESSWMVYFMVYSIVSSSLAFLFHSHQSFHI----SHIMNHSSHSQTM 230
Cdd:PRK06589  295 SLKALKTDNIKKILAYSTISQLSLaLLSAFILTPKALGAAILHLVSHSFAKICLFYSMGSIYSlkkeDQVDKLHGTSKSF 374

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 2312612558 231 KILTF---ISLLSLGGLPPFTGFIAKWFIIQELAFNHMFIT 268
Cdd:PRK06589  375 PLISFiisISSLSLIGIPIFSGFISKFLILLAASEQNQPWL 415
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH