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Conserved domains on  [gi|2313229590|gb|UXT61694|]
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formyl peptide receptor-like 1 inhibitory protein [Staphylococcus aureus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FPRL1_inhibitor super family cl27786
Formyl peptide receptor-like 1 inhibitory protein; This family consists of several formyl ...
 1-132 8.62e-83

Formyl peptide receptor-like 1 inhibitory protein; This family consists of several formyl peptide receptor-like 1 inhibitory proteins from Staphylococcus aureus. These are secreted proteins that block the formyl peptide receptor-like 1 found in neutrophils, monocytes, B cells, and NK cells; and inhibit the binding of chemoattractants (such as formylated peptides) to FPRL1, which initiate phagocyte mobilization towards the infection site.


The actual alignment was detected with superfamily member PRK13033:

Pssm-ID: 332607  Cd Length: 133  Bit Score: 238.78  E-value: 8.62e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2313229590   1 MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDEERADKLIKEADEKNEHYKGKTVEDLYVIA 80
Cdd:PRK13033    1 MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2313229590  81 KKMGKGNT-IAVVKIKDGGKNGYYTFDITRPLEEHRKNIPVVKNGEIDSISWY 132
Cdd:PRK13033   81 KKLSQGDVkKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY 133
 
Name Accession Description Interval E-value
PRK13033 PRK13033
formyl peptide receptor-like 1 inhibitory protein; Reviewed
 1-132 8.62e-83

formyl peptide receptor-like 1 inhibitory protein; Reviewed


Pssm-ID: 171849  Cd Length: 133  Bit Score: 238.78  E-value: 8.62e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2313229590   1 MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDEERADKLIKEADEKNEHYKGKTVEDLYVIA 80
Cdd:PRK13033    1 MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2313229590  81 KKMGKGNT-IAVVKIKDGGKNGYYTFDITRPLEEHRKNIPVVKNGEIDSISWY 132
Cdd:PRK13033   81 KKLSQGDVkKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY 133
FPRL1_inhibitor pfam16104
Formyl peptide receptor-like 1 inhibitory protein; This family consists of several formyl ...
 29-132 5.71e-49

Formyl peptide receptor-like 1 inhibitory protein; This family consists of several formyl peptide receptor-like 1 inhibitory proteins from Staphylococcus aureus. These are secreted proteins that block the formyl peptide receptor-like 1 found in neutrophils, monocytes, B cells, and NK cells; and inhibit the binding of chemoattractants (such as formylated peptides) to FPRL1, which initiate phagocyte mobilization towards the infection site.


Pssm-ID: 292722  Cd Length: 105  Bit Score: 152.16  E-value: 5.71e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2313229590  29 FFSYEWKGLEIAKNLADQAKKDEERADKLIKEADEKNEHYKGKTVEDLYVIAKKMGKGNT-IAVVKIKDGGKNGYYTFDI 107
Cdd:pfam16104   1 FFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVkKAVVRIKDGGPRDYYTFDL 80

                          90       100
                  ....*....|....*....|....*
gi 2313229590 108 TRPLEEHRKNIPVVKNGEIDSISWY 132
Cdd:pfam16104  81 TRPLEENRKNIKVVKNGEIDSITWY 105
 
Name Accession Description Interval E-value
PRK13033 PRK13033
formyl peptide receptor-like 1 inhibitory protein; Reviewed
 1-132 8.62e-83

formyl peptide receptor-like 1 inhibitory protein; Reviewed


Pssm-ID: 171849  Cd Length: 133  Bit Score: 238.78  E-value: 8.62e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2313229590   1 MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDEERADKLIKEADEKNEHYKGKTVEDLYVIA 80
Cdd:PRK13033    1 MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2313229590  81 KKMGKGNT-IAVVKIKDGGKNGYYTFDITRPLEEHRKNIPVVKNGEIDSISWY 132
Cdd:PRK13033   81 KKLSQGDVkKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY 133
FPRL1_inhibitor pfam16104
Formyl peptide receptor-like 1 inhibitory protein; This family consists of several formyl ...
 29-132 5.71e-49

Formyl peptide receptor-like 1 inhibitory protein; This family consists of several formyl peptide receptor-like 1 inhibitory proteins from Staphylococcus aureus. These are secreted proteins that block the formyl peptide receptor-like 1 found in neutrophils, monocytes, B cells, and NK cells; and inhibit the binding of chemoattractants (such as formylated peptides) to FPRL1, which initiate phagocyte mobilization towards the infection site.


Pssm-ID: 292722  Cd Length: 105  Bit Score: 152.16  E-value: 5.71e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2313229590  29 FFSYEWKGLEIAKNLADQAKKDEERADKLIKEADEKNEHYKGKTVEDLYVIAKKMGKGNT-IAVVKIKDGGKNGYYTFDI 107
Cdd:pfam16104   1 FFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVkKAVVRIKDGGPRDYYTFDL 80

                          90       100
                  ....*....|....*....|....*
gi 2313229590 108 TRPLEEHRKNIPVVKNGEIDSISWY 132
Cdd:pfam16104  81 TRPLEENRKNIKVVKNGEIDSITWY 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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