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Conserved domains on  [gi|1591805111|emb|VFT20465|]
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Heat shock protein GrpE [Klebsiella pneumoniae]

Protein Classification

nucleotide exchange factor GrpE( domain architecture ID 10793376)

nucleotide exchange factor GrpE functions as a nucleotide exchange factor for DnaK and participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may also function as a thermosensor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10325 PRK10325
heat shock protein GrpE; Provisional
 1-196 1.93e-122

heat shock protein GrpE; Provisional


:

Pssm-ID: 182379 [Multi-domain]  Cd Length: 197  Bit Score: 343.96  E-value: 1.93e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   1 MSSKEQKTPEGQAPEEIITEQHDDVEAVEPEVSAEQVDPRDEKIANLEAQLAEAQKREREVMLRAKADEDNLRRRTEQDI 80
Cdd:PRK10325    1 MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  81 EKAHKFALEKFVNELLPVIDSLDRALEVADKANPELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMV 160
Cdd:PRK10325   81 EKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV 160

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1591805111 161 ESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVAKAK 196
Cdd:PRK10325  161 ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAK 196
 
Name Accession Description Interval E-value
PRK10325 PRK10325
heat shock protein GrpE; Provisional
 1-196 1.93e-122

heat shock protein GrpE; Provisional


Pssm-ID: 182379 [Multi-domain]  Cd Length: 197  Bit Score: 343.96  E-value: 1.93e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   1 MSSKEQKTPEGQAPEEIITEQHDDVEAVEPEVSAEQVDPRDEKIANLEAQLAEAQKREREVMLRAKADEDNLRRRTEQDI 80
Cdd:PRK10325    1 MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  81 EKAHKFALEKFVNELLPVIDSLDRALEVADKANPELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMV 160
Cdd:PRK10325   81 EKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV 160

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1591805111 161 ESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVAKAK 196
Cdd:PRK10325  161 ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAK 196
GrpE COG0576
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein ...
 45-195 1.53e-56

Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440341 [Multi-domain]  Cd Length: 147  Bit Score: 175.34  E-value: 1.53e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  45 ANLEAQLAEAQKRerevMLRAKADEDNLRRRTEQDIEKAHKFALEKFVNELLPVIDSLDRALEVADKaNPELAPMVEGIE 124
Cdd:COG0576     2 EELEAELAELKDR----LLRLQAEFENYRKRTEREREEARKYALEKLAEDLLPVLDNLERALAAAEE-DEDVKSLLEGVE 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1591805111 125 LTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMVESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVAKA 195
Cdd:COG0576    77 MTLKQLLDVLEKHGVEEIEPVGEPFDPNLHEAVSQVPSPDVEPGTVVEVLQKGYRLGDRVLRPAMVVVAKG 147
GrpE cd00446
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70) ...
 59-192 1.18e-54

nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.


Pssm-ID: 271355 [Multi-domain]  Cd Length: 136  Bit Score: 169.99  E-value: 1.18e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  59 REVMLRAKADEDNLRRRTEQDIEKAHKFALEKFVNELLPVIDSLDRALEVADKaNPELAPMVEGIELTLKSMLDVVRKFG 138
Cdd:cd00446     4 KDKLLRAQAEFENYRKRTEKEKEEAKKYAIEKFAKDLLPVLDNLERALEAAPK-EEELKNLLEGVEMTLKQLLKVLEKHG 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1591805111 139 VEVIADTNVPLDPNVHQAIAMVESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTV 192
Cdd:cd00446    83 VEEIEPEGEKFDPNLHEAVMQVESPDKEPGTVVEVLQKGYKLHDRVLRPAMVVV 136
GrpE pfam01025
GrpE;
33-194 3.43e-50

GrpE;


Pssm-ID: 425996 [Multi-domain]  Cd Length: 165  Bit Score: 159.70  E-value: 3.43e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  33 SAEQVDPRDEKIANLEAQLAEAQKREREV---MLRAKADEDNLRRRTEQDIEKAHKFALEKFVNELLPVIDSLDRALEVA 109
Cdd:pfam01025   2 EKKNEEALTDEIESLEEEIEELEKKIEELkekLLRALAEFENLRKRTEKEKEEAKKFAIEKFAKDLLPVIDNLERALNSA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111 110 dKANPELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMVESEDVAAGNVLSVMQKGYTLNGRTIRAAM 189
Cdd:pfam01025  82 -PENEDVKSLLEGVEMTLKQLLKILEKHGVEKIEPEGEPFDPNLHEAVSQVPSPEKPEGTVVEVLQKGYKLHDRVLRPAM 160


                  ....*
gi 1591805111 190 VTVAK 194
Cdd:pfam01025 161 VVVSK 165
 
Name Accession Description Interval E-value
PRK10325 PRK10325
heat shock protein GrpE; Provisional
 1-196 1.93e-122

heat shock protein GrpE; Provisional


Pssm-ID: 182379 [Multi-domain]  Cd Length: 197  Bit Score: 343.96  E-value: 1.93e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   1 MSSKEQKTPEGQAPEEIITEQHDDVEAVEPEVSAEQVDPRDEKIANLEAQLAEAQKREREVMLRAKADEDNLRRRTEQDI 80
Cdd:PRK10325    1 MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  81 EKAHKFALEKFVNELLPVIDSLDRALEVADKANPELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMV 160
Cdd:PRK10325   81 EKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV 160

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1591805111 161 ESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVAKAK 196
Cdd:PRK10325  161 ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAK 196
PRK14150 PRK14150
heat shock protein GrpE; Provisional
 1-194 3.11e-94

heat shock protein GrpE; Provisional


Pssm-ID: 184539 [Multi-domain]  Cd Length: 193  Bit Score: 272.56  E-value: 3.11e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   1 MSSKEQKTPEGQAPEEIITEQHDDVEAVEPEVsAEQVDPRDEKIANLEAQLAEAQKREREVMLRAKADEDNLRRRTEQDI 80
Cdd:PRK14150    1 MSNEEQKTPQEQVSEEIEAEVEQQEEADEAEL-EDELDEADARIAELEAQLAEAQAEERDSVLRARAEVENIRRRAEQDV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  81 EKAHKFALEKFVNELLPVIDSLDRALEVADKANPELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMV 160
Cdd:PRK14150   80 EKAHKFALEKFANELLPVIDNLERALQAADKENEALKALIEGVELTLKSLLDTVAKFGVEVVGPVGEPFNPEVHQAISMQ 159

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1591805111 161 ESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14150  160 ESEDHEPNTVMMVMQKGYTLNGRLLRPAMVMVSK 193
GrpE COG0576
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein ...
 45-195 1.53e-56

Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440341 [Multi-domain]  Cd Length: 147  Bit Score: 175.34  E-value: 1.53e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  45 ANLEAQLAEAQKRerevMLRAKADEDNLRRRTEQDIEKAHKFALEKFVNELLPVIDSLDRALEVADKaNPELAPMVEGIE 124
Cdd:COG0576     2 EELEAELAELKDR----LLRLQAEFENYRKRTEREREEARKYALEKLAEDLLPVLDNLERALAAAEE-DEDVKSLLEGVE 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1591805111 125 LTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMVESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVAKA 195
Cdd:COG0576    77 MTLKQLLDVLEKHGVEEIEPVGEPFDPNLHEAVSQVPSPDVEPGTVVEVLQKGYRLGDRVLRPAMVVVAKG 147
GrpE cd00446
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70) ...
 59-192 1.18e-54

nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.


Pssm-ID: 271355 [Multi-domain]  Cd Length: 136  Bit Score: 169.99  E-value: 1.18e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  59 REVMLRAKADEDNLRRRTEQDIEKAHKFALEKFVNELLPVIDSLDRALEVADKaNPELAPMVEGIELTLKSMLDVVRKFG 138
Cdd:cd00446     4 KDKLLRAQAEFENYRKRTEKEKEEAKKYAIEKFAKDLLPVLDNLERALEAAPK-EEELKNLLEGVEMTLKQLLKVLEKHG 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1591805111 139 VEVIADTNVPLDPNVHQAIAMVESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTV 192
Cdd:cd00446    83 VEEIEPEGEKFDPNLHEAVMQVESPDKEPGTVVEVLQKGYKLHDRVLRPAMVVV 136
PRK14151 PRK14151
heat shock protein GrpE; Provisional
 20-195 1.26e-54

heat shock protein GrpE; Provisional


Pssm-ID: 172640 [Multi-domain]  Cd Length: 176  Bit Score: 171.50  E-value: 1.26e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  20 EQHDDVEAvePEVSAEQVDPRDE---KIANLEAQLAEAQkrerEVMLRAKADEDNLRRRTEQDIEKAHKFALEKFVNELL 96
Cdd:PRK14151    4 EQTLDLQA--PEAAQAEAAAGDDltaRVQELEEQLAAAK----DQSLRAAADLQNVRRRAEQDVEKAHKFALEKFAGDLL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  97 PVIDSLDRALEVADKANPELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMVESEDVAAGNVLSVMQK 176
Cdd:PRK14151   78 PVVDSLERGLELSSADDEAIKPMREGVELTLKMFQDTLKRYQLEAVDPHGEPFNPEHHQAMAMQESADVEPNSVLKVFQK 157

                         170
                  ....*....|....*....
gi 1591805111 177 GYTLNGRTIRAAMVTVAKA 195
Cdd:PRK14151  158 GYLLNGRLLRPAMVVVSKA 176
GrpE pfam01025
GrpE;
33-194 3.43e-50

GrpE;


Pssm-ID: 425996 [Multi-domain]  Cd Length: 165  Bit Score: 159.70  E-value: 3.43e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  33 SAEQVDPRDEKIANLEAQLAEAQKREREV---MLRAKADEDNLRRRTEQDIEKAHKFALEKFVNELLPVIDSLDRALEVA 109
Cdd:pfam01025   2 EKKNEEALTDEIESLEEEIEELEKKIEELkekLLRALAEFENLRKRTEKEKEEAKKFAIEKFAKDLLPVIDNLERALNSA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111 110 dKANPELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMVESEDVAAGNVLSVMQKGYTLNGRTIRAAM 189
Cdd:pfam01025  82 -PENEDVKSLLEGVEMTLKQLLKILEKHGVEKIEPEGEPFDPNLHEAVSQVPSPEKPEGTVVEVLQKGYKLHDRVLRPAM 160


                  ....*
gi 1591805111 190 VTVAK 194
Cdd:pfam01025 161 VVVSK 165
PRK14139 PRK14139
heat shock protein GrpE; Provisional
 5-196 7.24e-46

heat shock protein GrpE; Provisional


Pssm-ID: 237621 [Multi-domain]  Cd Length: 185  Bit Score: 149.35  E-value: 7.24e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   5 EQKTPEGQAPEeiiTEQHDDVEAVEPEVSAEQVDPrdekIANLEAQLAEAQKREREV---MLRAKADEDNLRRRTEQDIE 81
Cdd:PRK14139    2 ENTQQNPSEQE---AEEAGAAAQAAAAAAAAAEDA----APALEAELAEAEAKAAELqdsFLRAKAETENVRRRAQEDVA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  82 KAHKFALEKFVNELLPVIDSLDRALevADKaNPELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMVE 161
Cdd:PRK14139   75 KAHKFAIESFAESLLPVKDSLEAAL--ADE-SGDLEKLREGVELTLKQLTSAFEKGRVVEINPVGEKFDPHQHQAISMVP 151

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1591805111 162 SEDvAAGNVLSVMQKGYTLNGRTIRAAMVTVAKAK 196
Cdd:PRK14139  152 AEQ-EPNTVVAVLQKGYTIADRVLRPALVTVAAPK 185
PRK14140 PRK14140
heat shock protein GrpE; Provisional
 1-194 1.89e-40

heat shock protein GrpE; Provisional


Pssm-ID: 237622 [Multi-domain]  Cd Length: 191  Bit Score: 135.90  E-value: 1.89e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   1 MSSKEQKT--PEGQAPEEIITEQHDDVEAVEPEVSAEQVDPRDEKIANLEAQLAEAQKRerevMLRAKADEDNLRRRTEQ 78
Cdd:PRK14140    1 MEEKNEQVeeEVEETEVEEAVEDEVEEETVEEESEAELLDEEQAKIAELEAKLDELEER----YLRLQADFENYKRRIQK 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  79 DIEKAHKFALEKFVNELLPVIDSLDRALEVADKaNPELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIA 158
Cdd:PRK14140   77 ENEAAEKYRAQSLASDLLPALDNFERALQIEAD-DEQTKSLLKGVEMVHRQLLEALKKEGVEVIEAVGEQFDPNLHQAVM 155

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1591805111 159 MVESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14140  156 QDEDEDFESNEVVEELQKGYKLKDRVIRPSMVKVNQ 191
PRK14144 PRK14144
heat shock protein GrpE; Provisional
 4-194 4.22e-38

heat shock protein GrpE; Provisional


Pssm-ID: 184535 [Multi-domain]  Cd Length: 199  Bit Score: 130.23  E-value: 4.22e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   4 KEQKTPEGQAPEEIITEQHDD-VEAVEPEVSAEQVDPRDEKIAnleaqLAEAQKRER-EVMLRAKADEDNLRRRTEQDIE 81
Cdd:PRK14144   13 KDEHKEEHKVENEILEEETDEeSQHQEPALGHPSYTALEEQLT-----LAEQKAHENwEKSVRALAELENVRRRMEREVA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  82 KAHKFALEKFVNELLPVIDSLDRALEVADKAnpELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMVE 161
Cdd:PRK14144   88 NAHKYGVEKLISALLPVVDSLEQALQLADKN--SDPSMHEGLELTMKLFLDALQKFDVEQIDPLGQTFDPQQHEAMSMQP 165

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1591805111 162 SEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14144  166 APGAPPNSVITVFQKGYKLSDRVIRPARVIVST 198
PRK14147 PRK14147
heat shock protein GrpE; Provisional
 18-194 1.32e-35

heat shock protein GrpE; Provisional


Pssm-ID: 237625 [Multi-domain]  Cd Length: 172  Bit Score: 122.75  E-value: 1.32e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  18 ITEQHDDVEAVEPEVSAEQVDPRDEKIANLEAQLAEAQKRerevMLRAKADEDNLRRRTEQDIEKAHKFALEKFVNELLP 97
Cdd:PRK14147    1 MNQDHPEFDSEDLAQNPPETDPLKAEVESLRSEIALVKAD----ALRERADLENQRKRIARDVEQARKFANEKLLGELLP 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  98 VIDSLDRALEVAdkaNPELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMVESEDVAAGNVLSVMQKG 177
Cdd:PRK14147   77 VFDSLDAGLTAA---GTEPSPLRDGLELTYKQLLKVAADNGLTLLDPVGQPFNPEHHQAISQGEAEGVAPGHVVQVFQKG 153

                         170
                  ....*....|....*..
gi 1591805111 178 YTLNGRTIRAAMVTVAK 194
Cdd:PRK14147  154 YLLNERLLRPALVVVAK 170
PRK14141 PRK14141
heat shock protein GrpE; Provisional
 3-194 7.89e-33

heat shock protein GrpE; Provisional


Pssm-ID: 172630  Cd Length: 209  Bit Score: 116.69  E-value: 7.89e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   3 SKEQKTPEGQAPEEIiteqhDDVEAVEPEVSAEQVDPRDEKIANLEAQLAEAqkreREVMLRAKADEDNLRRRTEQDIEK 82
Cdd:PRK14141    4 EKNKNGNPADAARDA-----NNPVDREAKPYEMEDDPEPDPLEALKAENAEL----KDRMLRLAAEMENLRKRTQRDVAD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  83 AHKFALEKFVNELLPVIDSLDRAL-----EVADKANPELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAI 157
Cdd:PRK14141   75 ARAYGIAGFARDMLSVSDNLRRALdaipaEARAAADAGLKALIEGVEMTERAMLNALERHGVKKLDPEGQKFDPNFHQAM 154

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1591805111 158 AMVESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14141  155 FEVPNPDVPNNTVVQVVQAGYTIGERVLRPAMVGVAK 191
PRK14158 PRK14158
heat shock protein GrpE; Provisional
 12-194 8.12e-33

heat shock protein GrpE; Provisional


Pssm-ID: 172646 [Multi-domain]  Cd Length: 194  Bit Score: 116.57  E-value: 8.12e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  12 QAPEEIITEQHDDVEAVEPEVSAEQVDPRDEKIANLEAQLA--EAQKRER-EVMLRAKADEDNLRRRTEQDIEKAHKFAL 88
Cdd:PRK14158   10 QIAEALKAKAAKEAEAAQGKPEAAQPVAAADRIKELEEALAakEAEAAANwDKYLRERADLENYRKRVQKEKEELLKYGN 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  89 EKFVNELLPVIDSLDRALEVADKANpeLAPMVEGIELTLKSMLDVVRKFGVEVI-ADTNVPLDPNVHQAIAMVESEDVAA 167
Cdd:PRK14158   90 ESLILEILPAVDNMERALDHADEES--MSAIIEGIRMTLSMLLSTLKKFGVTPVeAEKGTPFDPAYHQAMCQVESAEQEP 167

                         170       180
                  ....*....|....*....|....*..
gi 1591805111 168 GNVLSVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14158  168 NTVVAVFQKGYLLNERLLRPAMVSVAT 194
PRK14148 PRK14148
heat shock protein GrpE; Provisional
 2-194 5.22e-31

heat shock protein GrpE; Provisional


Pssm-ID: 172637 [Multi-domain]  Cd Length: 195  Bit Score: 111.77  E-value: 5.22e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   2 SSKEQKTPEGQAPEEIITEQHDDVEAVEPEVSAEQVDPRDEKIANLEaqlaEAQKREREVMLRAKADEDNLRRRTEQDIE 81
Cdd:PRK14148    7 SNVEDKSLDIETAAQVETAQESASGALEELSVEEQLERAKDTIKELE----DSCDQFKDEALRAKAEMENIRKRAERDVS 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  82 KAHKFALEKFVNELLPVIDSLDRALEVADKANPELApMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMVE 161
Cdd:PRK14148   83 NARKFGIEKFAKELLPVIDSIEQALKHEVKLEEAIA-MKEGIELTAKMLVDILKKNGVEELDPKGEKFDPNLHEAMAMIP 161

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1591805111 162 SEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14148  162 NPEFEDNTIFDVFQKGYMLNGRIVRAAKVVIVK 194
PRK14149 PRK14149
heat shock protein GrpE; Provisional
 1-194 1.05e-29

heat shock protein GrpE; Provisional


Pssm-ID: 184538 [Multi-domain]  Cd Length: 191  Bit Score: 108.42  E-value: 1.05e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   1 MSSKEQKTPEGQAPEEIITEQHddVEAVEPEVSAEQVDPRDEKIANLEAQLAEAqkreREVMLRAKADEDNLRRRTEQDI 80
Cdd:PRK14149    4 EHNQEHDHLSQKEPESEEKACA--CKEQQGEEKQEASEKEGEIKEDFELKYKEM----HEKYLRVHADFENVKKRLERDK 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  81 EKAHKFALEKFVNELLPVIDSLDRALEVAdKANPELAPMVEGIELTLKSMLDVVRKFGVEVIAdTNVPLDPNVHQAIAMV 160
Cdd:PRK14149   78 SMALEYAYEKIALDLLPVIDALLGALKSA-AEVDKESALTKGLELTMEKLHEVLARHGIEGIE-CLEEFDPNFHNAIMQV 155

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1591805111 161 ESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14149  156 KSEEKENGKIVQVLQQGYKYKGRVLRPAMVSIAK 189
PRK14155 PRK14155
heat shock protein GrpE; Provisional
 26-193 1.57e-28

heat shock protein GrpE; Provisional


Pssm-ID: 237627 [Multi-domain]  Cd Length: 208  Bit Score: 105.82  E-value: 1.57e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  26 EAVEPEVSAEQVDPRDEKIANLEAQLAEAQKRerevMLRAKADEDNLRRRTEQDIEKAHKFALEKFVNELLPVIDSLDRA 105
Cdd:PRK14155    4 EQTPAEDGPFEADDAAQEIEALKAEVAALKDQ----ALRYAAEAENTKRRAEREMNDARAYAIQKFARDLLGAADNLGRA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111 106 LEVA--DKANPELAPMVEGIELTLKSMLDVVRKFGVEVIADT-NVPLDPNVHQAIAMVESEDVAAGNVLSVMQKGYTLNG 182
Cdd:PRK14155   80 TAASpkDSADPAVKNFIIGVEMTEKELLGAFERNGLKKIDPAkGDKFDPHLHQAMMEQPSTEVAAGGVLQVMQAGYELMG 159

                         170
                  ....*....|.
gi 1591805111 183 RTIRAAMVTVA 193
Cdd:PRK14155  160 RLVRPAMVAVA 170
PRK14154 PRK14154
heat shock protein GrpE; Provisional
 1-193 1.60e-25

heat shock protein GrpE; Provisional


Pssm-ID: 237626 [Multi-domain]  Cd Length: 208  Bit Score: 97.96  E-value: 1.60e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   1 MSSKEQKTPEGQAPE--EIITEQHDDVEAVEPEVSAEQVDPRD----EKIANLEAQLAEAQKREREV---MLRAKADEDN 71
Cdd:PRK14154    5 MSSKNNPESETKAKNkwEKVMEAEEEQEEGGGDGSQEMEPHREglefPSREKLEGQLTRMERKVDEYktqYLRAQAEMDN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  72 LRRRTEQDIEKAHKFALEKFVNELLPVIDSLDRALEVADKANPELAPMVEGIELTLKSMLDVVRKFGVEVI-ADTNVPLD 150
Cdd:PRK14154   85 LRKRIEREKADIIKFGSKQLITDLLPVADSLIHGLESPASEDPQVKSMRDGMSLTLDLLHNTLAKHGVQVInPNPGDPFD 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1591805111 151 PNVHQAIAMVESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVA 193
Cdd:PRK14154  165 PALHEAMSVQAVPDAKPDTIIQVLQKGYQLNGRVLRAARVIVA 207
PRK14153 PRK14153
heat shock protein GrpE; Provisional
 29-194 1.80e-25

heat shock protein GrpE; Provisional


Pssm-ID: 184540 [Multi-domain]  Cd Length: 194  Bit Score: 97.22  E-value: 1.80e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  29 EPEVSAEQVDPRDEKIANLEAQLAEAQKRE-REVMLRAKADEDNLRRRTEQDIEKAHKFALEKFVNELLPVIDSLDRALE 107
Cdd:PRK14153   22 SAEEAEELKEEPEDSTADSETEKCREEIESlKEQLFRLAAEFDNFRKRTAREMEENRKFVLEQVLLDLLEVTDNFERALE 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111 108 VADKANpELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMVESEDVAAGNVLSVMQKGYTLNGRTIRA 187
Cdd:PRK14153  102 SARTAE-DMNSIVEGIEMVSKQFFSILEKYGLERIECEGEEFDPHRHEAMMHVETSEVPDNTIVDVCKPGYALNSKVIRP 180


                  ....*..
gi 1591805111 188 AMVTVAK 194
Cdd:PRK14153  181 AMVSVAR 187
PRK14159 PRK14159
heat shock protein GrpE; Provisional
 18-194 2.18e-22

heat shock protein GrpE; Provisional


Pssm-ID: 172647 [Multi-domain]  Cd Length: 176  Bit Score: 88.98  E-value: 2.18e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  18 ITEQHDDVEAVEPEVSAEQVDPRDEKIANLEAQLAEAQKRE-REVMLRAKADEDNLRRRTEQDIEKAHKFALEKFVNELL 96
Cdd:PRK14159    1 MSEQKQEFENENAENSEHLQDENLQNIEDVEQNKLQKDYDElKDKYMRANAEFENIKKRMEKEKLSAMAYANESFAKDLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  97 PVIDSLDRALEVadKANPELAPMV-EGIELTLKSMLDVVRKFGVEVIADTNvPLDPNVHQAIAMVESEDVAAGNVLSVMQ 175
Cdd:PRK14159   81 DVLDALEAAVNV--ECHDEISLKIkEGVQNTLDLFLKKLEKHGVALIKEEK-EFDPNLHEAMFHVDSENHQSGEVVQVLQ 157

                         170
                  ....*....|....*....
gi 1591805111 176 KGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14159  158 KGYKIADRVIRPTKVSVAK 176
PRK14162 PRK14162
heat shock protein GrpE; Provisional
 3-194 1.11e-21

heat shock protein GrpE; Provisional


Pssm-ID: 237631 [Multi-domain]  Cd Length: 194  Bit Score: 87.58  E-value: 1.11e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   3 SKEQKTPEGQAPEEIITEQHDdvEAVEPEVSAEQVDPRDEKIANLEAQLAEAQKREREV---MLRAKADEDNLRRRTEQD 79
Cdd:PRK14162    2 SKEEFPSEKDLPQEETTDEAP--KKEAKEAPKEEDQEKQNPVEDLEKEIADLKAKNKDLedkYLRSQAEIQNMQNRYAKE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  80 IEKAHKFALEKFVNELLPVIDSLDRALEVadKANPELAPMVE-GIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIA 158
Cdd:PRK14162   80 RAQLIKYESQSLAKDVLPAMDNLERALAV--KADDEAAKQLKkGVQMTLDHLVKALKDHGVTEIKADGEKFDPTLHQAVQ 157

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1591805111 159 MVESE-DVAAGNVLSVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14162  158 TVAAEnDDQKDHVVQVLQKGYQYKDRTLRPAMVVVAQ 194
PRK14143 PRK14143
heat shock protein GrpE; Provisional
 2-196 1.37e-20

heat shock protein GrpE; Provisional


Pssm-ID: 237624 [Multi-domain]  Cd Length: 238  Bit Score: 85.55  E-value: 1.37e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   2 SSKEQKTPEGQAPEEIITEQHDDVEAVEPEVSAEQVDPRD-EKIANLEAQLaEAQKREREVM----LRAKADEDNLRRRT 76
Cdd:PRK14143   26 ESSEEVTEQEAELTNPEGDAAEAESSPDSGSAASETAADNaARLAQLEQEL-ESLKQELEELnsqyMRIAADFDNFRKRT 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  77 EQDIEKAHKFALEKFVNELLPVIDSLDRALEvadkanpELAPMVEGiELTL--------KSMLDVVRKFGVEVIADTNVP 148
Cdd:PRK14143  105 SREQEDLRLQLKCNTLSEILPVVDNFERARQ-------QLKPEGEE-AQALhrsyqglyKQLVDVLKRLGVSPMRVVGQE 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1591805111 149 LDPNVHQAIAMVESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVAKAK 196
Cdd:PRK14143  177 FDPNLHEAVLREPSDEHPEDVVLEELQRGYHLGGRVLRHAMVKVSMGP 224
PRK14160 PRK14160
heat shock protein GrpE; Provisional
 1-194 7.89e-20

heat shock protein GrpE; Provisional


Pssm-ID: 237629 [Multi-domain]  Cd Length: 211  Bit Score: 82.88  E-value: 7.89e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   1 MSSKEQKTPEGQAPEEIITEQHDDVEAVEPEVSAEQVDPRDEKiANLEAQLAEAQKRerevMLRAKADEDNLRRRTEQDI 80
Cdd:PRK14160   28 KGKEEDLEFEEIEKEEIIEDSEESNEVKIEELKDENNKLKEEN-KKLENELEALKDR----LLRTVAEYDNYRKRTAKEK 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  81 EKAHKFALEKFVNELLPVIDSLDRALEVADKANPelapMVEGIELTLKSMLDVVRKFGVEVIaDTNVPLDPNVHQAIAMV 160
Cdd:PRK14160  103 EGIYSDACEDVLKELLPVLDNLERAAAVEGSVED----LKKGIEMTVKQFKTSLEKLGVEEI-STEGEFDPNLHNAVMHV 177

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1591805111 161 ESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14160  178 EDENYGENEIVEVFQKGYKRGDKVIRYSMVKVAN 211
PRK14145 PRK14145
heat shock protein GrpE; Provisional
 23-194 3.13e-19

heat shock protein GrpE; Provisional


Pssm-ID: 184536 [Multi-domain]  Cd Length: 196  Bit Score: 81.12  E-value: 3.13e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  23 DDVEAVEPEVSAEQVDPRDEKIANLEAQLAEAQKReREVMLRAKADEDNLRRRTEQDIEKAHKFALEKFVNELLPVIDSL 102
Cdd:PRK14145   30 EDEQAQQNQPQQQTVDEIEELKQKLQQKEVEAQEY-LDIAQRLKAEFENYRKRTEKEKSEMVEYGKEQVILELLPVMDNF 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111 103 DRALEvadkANPELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMVESEDVAAGNVLSVMQKGYTLNG 182
Cdd:PRK14145  109 ERALA----SSGDYNSLKEGIELIYRQFKKILDKFGVKEIEAEGQIFDPYKHHAVMQEEVEGKQPNEIIEVFQKGYYLKD 184

                         170
                  ....*....|..
gi 1591805111 183 RTIRAAMVTVAK 194
Cdd:PRK14145  185 KVIRPSLVKVAK 196
PRK14161 PRK14161
heat shock protein GrpE; Provisional
 26-194 3.47e-18

heat shock protein GrpE; Provisional


Pssm-ID: 237630 [Multi-domain]  Cd Length: 178  Bit Score: 78.09  E-value: 3.47e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  26 EAVEPEVSAEQVDPRDEKIANLEAQLAEAQKRerevMLRAKADEDNLRRRTEQDIEKAHKFALEKFVNELLPVIDSLDRA 105
Cdd:PRK14161   10 EQTINDIAEEIVETANPEITALKAEIEELKDK----LIRTTAEIDNTRKRLEKARDEAKDYAIATFAKELLNVSDNLSRA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111 106 LE-VADKANPELAPMVEGIELTLKSMLDVVRKFGVEVIA-DTNVPLDPNVHQAIAMVESEDVAAGNVLSVMQKGYTLNGR 183
Cdd:PRK14161   86 LAhKPANSDVEVTNIIAGVQMTKDELDKVFHKHHIEEIKpEIGSMFDYNLHNAISQIEHPDHAPNSIITLMQSGYKIRDR 165

                         170
                  ....*....|.
gi 1591805111 184 TIRAAMVTVAK 194
Cdd:PRK14161  166 LLRPATVQVVK 176
PRK14163 PRK14163
heat shock protein GrpE; Provisional
 9-196 1.61e-17

heat shock protein GrpE; Provisional


Pssm-ID: 184546 [Multi-domain]  Cd Length: 214  Bit Score: 77.09  E-value: 1.61e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   9 PEGQAPEEIiteqhdDVEAVEPEVSAEQVDPrdEKIANLEAQLAEAQKR--EREVML-RAKADEDNLRRRTEQDIEKAHK 85
Cdd:PRK14163   15 PSGATPDDA------EPKAASEEGAAPAGDA--AATAGLTAQLDQVRTAlgERTADLqRLQAEYQNYRRRVERDRVTVKE 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  86 FALEKFVNELLPVIDSLDRALEVADkanpelapMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAMVESEDV 165
Cdd:PRK14163   87 IAVANLLSELLPVLDDVGRAREHGE--------LVGGFKSVAESLETTVAKLGLQQFGKEGEPFDPTIHEALMHSYAPDV 158

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1591805111 166 AAGNVLSVMQKGYTLNGRTIRAAMVTVAKAK 196
Cdd:PRK14163  159 TETTCVAILQPGYRIGERTIRPARVAVAEPQ 189
PRK14146 PRK14146
heat shock protein GrpE; Provisional
 2-196 1.41e-16

heat shock protein GrpE; Provisional


Pssm-ID: 172635 [Multi-domain]  Cd Length: 215  Bit Score: 74.38  E-value: 1.41e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   2 SSKEQKTPEGQAPEEIITE-QHDDVEAVEPEVSAEQVDPRDEKIANLEAQLA---EAQKREREVM----LRAKADEDNLR 73
Cdd:PRK14146    9 TSEEAKANEKKSQSQTLEEsKLENMNSEESQTITEETQEQAVEGAETETSLQkelDNAKKEIESLkdswARERAEFQNFK 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  74 RRTEQDIEKAHKFALEKFVNELLPVIDSLDRALEVADKAnPELAPMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNV 153
Cdd:PRK14146   89 RRSAQEFVSIRKEAVKSLVSGFLNPIDNLERVGATQNQS-EELKPFVEGVKMILKEFYSVLEKSNVIRFDPKGEPFDPMS 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1591805111 154 HQAIAMVESEDVAAGNVLSVMQKGYTL----NGRTIRAAMVTVAKAK 196
Cdd:PRK14146  168 MEALSSEEGDQYSEETVIDVYQAGYYYkeneDKFTLRPARVRIGKPK 214
PRK14164 PRK14164
heat shock protein GrpE; Provisional
 5-193 1.26e-15

heat shock protein GrpE; Provisional


Pssm-ID: 237632 [Multi-domain]  Cd Length: 218  Bit Score: 72.14  E-value: 1.26e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   5 EQKTPEGQAPEEIITEQHDDVEAVEPEVSAEQVDPRDEkiANLEAQLAEaqkrEREVMLRAKADEDNLRRRTEQDIEKAH 84
Cdd:PRK14164   42 EDDPFGDAVEGEIDPDLEADLEDLLDDVDPELADDGEA--STVEAQLAE----RTEDLQRVTAEYANYRRRTERERQAII 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  85 KFALEKFVNELLPVIDSLDRALEVADkanpelapMVEGielTLKSMLD----VVRKFGVEVIADTNVPLDPNVHQAIAMV 160
Cdd:PRK14164  116 ETAKAGVATDLLPILDDLDLAEQHGD--------LNEG---PLKAFSDkltnVLAGLKVEKFGEEGDAFDPEIHEAVQDL 184

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1591805111 161 ESEDVAAgnVLSVMQKGYTLNGRTIRAAMVTVA 193
Cdd:PRK14164  185 SSGDEKV--LGTVLRKGYRMGDRVLRTAMVIIA 215
PRK14156 PRK14156
heat shock protein GrpE; Provisional
 15-194 2.25e-13

heat shock protein GrpE; Provisional


Pssm-ID: 237628 [Multi-domain]  Cd Length: 177  Bit Score: 65.24  E-value: 2.25e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  15 EEIITEQHDD-VEAVEPEVSAEQVDPRDEKIANLEAQLAEAQKREREvMLRAKADEDNLRRRTEQDIEKAHKFALEKFVN 93
Cdd:PRK14156    3 EEIKNEEVEEeVEATETEETVEEVVEETPEKSELELANERADEFENK-YLRAHAEMQNIQRRANEERQQLQRYRSQDLAK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  94 ELLPVIDSLDRALEVADKANpelaPMVEGIELTLKSMLDVVRKFGVEVIADTNvpLDPNVHQAIAMVESEDV-AAGNVLS 172
Cdd:PRK14156   82 AILPSLDNLERALAVEGLTD----DVKKGLEMVQESLIQALKEEGVEEVAVDS--FDHNLHMAVQTLPADDEhPADSIAQ 155

                         170       180
                  ....*....|....*....|..
gi 1591805111 173 VMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14156  156 VFQKGYKLHERLLRPAMVVVYN 177
PRK14157 PRK14157
heat shock protein GrpE; Provisional
 3-193 1.22e-08

heat shock protein GrpE; Provisional


Pssm-ID: 184543 [Multi-domain]  Cd Length: 227  Bit Score: 53.04  E-value: 1.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   3 SKEQKTPEGQAPEEIITEQHDDVEAVEPEVSAEQVDPRDEKIANLEAQLAEAQKRER---EVMLRAKADEDNLRRRTEQD 79
Cdd:PRK14157   38 SGEQQDSAAQADANAGADAAPAAAEGEAKAAAEKTGEAQSDSDDTLTPLGQAKKEAAeylEALQRERAEFINYRNRTQKE 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  80 IEKAHKFALEKFVNELLPVIDSLDRALEVADkanpelapMVEGIELTLKSMLDVVRKFGVEVIADTNVPLDPNVHQAIAM 159
Cdd:PRK14157  118 QDRFRQHGIIDVLTALLPALDDIDRIREHSE--------MDDSFKAVAAKIDKAFEKFGVEKFGEKGEDFDPTKHDAILH 189

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1591805111 160 VESEDVAAGNVLSVMQKGYTLNGRTIRAAMVTVA 193
Cdd:PRK14157  190 KPDPDAEKETVDTVVEAGYRIGDRVIRAARVVVA 223
PRK14142 PRK14142
heat shock protein GrpE; Provisional
 9-192 2.60e-07

heat shock protein GrpE; Provisional


Pssm-ID: 237623  Cd Length: 223  Bit Score: 49.23  E-value: 2.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111   9 PEGQAPEEIITEqhdDVEAVEPEV-SAEQVDPRDEKIANLEAQLAEAQKREREV---MLRAKADEDNLRRRTEQDIEKAH 84
Cdd:PRK14142    2 PDGNSGEQVTVT---DKRRIDPETgEVRHVPPGDMPGGTAAADAAHTEDKVAELtadLQRVQADFANYRKRALRDQQAAA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591805111  85 KFALEKFVNELLPVIDSLDRALEVADKANPELAPMVEGIELTLKSMLDVVrkFGVEviadtNVPLDPNVHQAIAMVESED 164
Cdd:PRK14142   79 DRAKASVVSQLLGVLDDLERARKHGDLESGPLKSVADKLDSALTGLGLVA--FGAE-----GEDFDPVLHEAVQHEGDGG 151

                         170       180
                  ....*....|....*....|....*....
gi 1591805111 165 VAAGNVL-SVMQKGYTLNGRTIRAAMVTV 192
Cdd:PRK14142  152 QGSKPVIgTVMRQGYQLGEQVLRHALVGV 180
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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