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Conserved domains on  [gi|1591805117|emb|VFT20511|]
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yfjF [Klebsiella pneumoniae]

Protein Classification

RnfH family protein( domain architecture ID 10006787)

RnfH family protein, a member of the ubiquitin superfamily, is involved in transporting electrons for various reductive reactions such as nitrogen fixation and may also play a role in the SmpB-tmRNA-based tagging and degradation system of bacteria

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PasI COG2914
Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH ...
 5-49 1.34e-24

Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily [Defense mechanisms];


:

Pssm-ID: 442158  Cd Length: 92  Bit Score: 86.33  E-value: 1.34e-24
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 1591805117  5 WRKNKLGIYSRPVKLHDEVHDGDRVEIYRPLIADPKELRRQRAEK 49
Cdd:COG2914   48 LAKNKVGIFGKLVKLDTVLRDGDRVEIYRPLIADPKEARRRRAAK 92
 
Name Accession Description Interval E-value
PasI COG2914
Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH ...
 5-49 1.34e-24

Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily [Defense mechanisms];


Pssm-ID: 442158  Cd Length: 92  Bit Score: 86.33  E-value: 1.34e-24
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 1591805117  5 WRKNKLGIYSRPVKLHDEVHDGDRVEIYRPLIADPKELRRQRAEK 49
Cdd:COG2914   48 LAKNKVGIFGKLVKLDTVLRDGDRVEIYRPLIADPKEARRRRAAK 92
PRK01777 PRK01777
RnfH family protein;
6-53 1.90e-24

RnfH family protein;


Pssm-ID: 234982  Cd Length: 95  Bit Score: 86.19  E-value: 1.90e-24
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 1591805117  6 RKNKLGIYSRPVKLHDEVHDGDRVEIYRPLIADPKELRRQRAEKSAAK 53
Cdd:PRK01777  48 AKNKVGIYSRPAKLTDVLRDGDRVEIYRPLLADPKELRRKRAEQAKKK 95
Ub-RnfH pfam03658
RnfH family Ubiquitin; A member of the RnfH family of the ubiquitin superfamily. Members of ...
 7-44 3.56e-20

RnfH family Ubiquitin; A member of the RnfH family of the ubiquitin superfamily. Members of this family strongly co-occur in two distinct gene neighborhood contexts. In one it is associated with a START domain protein, a membrane protein SmpA and the transfer mRNA binding protein SmpB. This association suggests a possible role in the SmpB-tmRNA-based tagging and degadation system of bacteria, which is interesting given that other members of the ubiquitin system are analogously involved in protein-tagging and degradation across eukaryotes and various prokaryotes. The second context in which the RnfH genes are present is in a membrane associated complex involved in transporting electrons for various reductive reactions such as nitrogen fixation.


Pssm-ID: 427429  Cd Length: 83  Bit Score: 75.16  E-value: 3.56e-20
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 1591805117  7 KNKLGIYSRPVKLHDEVHDGDRVEIYRPLIADPKELRR 44
Cdd:pfam03658 46 TNKVGIFGKLVKLDTVLRDGDRVEIYRPLIADPKEARR 83
 
Name Accession Description Interval E-value
PasI COG2914
Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH ...
 5-49 1.34e-24

Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily [Defense mechanisms];


Pssm-ID: 442158  Cd Length: 92  Bit Score: 86.33  E-value: 1.34e-24
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 1591805117  5 WRKNKLGIYSRPVKLHDEVHDGDRVEIYRPLIADPKELRRQRAEK 49
Cdd:COG2914   48 LAKNKVGIFGKLVKLDTVLRDGDRVEIYRPLIADPKEARRRRAAK 92
PRK01777 PRK01777
RnfH family protein;
6-53 1.90e-24

RnfH family protein;


Pssm-ID: 234982  Cd Length: 95  Bit Score: 86.19  E-value: 1.90e-24
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 1591805117  6 RKNKLGIYSRPVKLHDEVHDGDRVEIYRPLIADPKELRRQRAEKSAAK 53
Cdd:PRK01777  48 AKNKVGIYSRPAKLTDVLRDGDRVEIYRPLLADPKELRRKRAEQAKKK 95
Ub-RnfH pfam03658
RnfH family Ubiquitin; A member of the RnfH family of the ubiquitin superfamily. Members of ...
 7-44 3.56e-20

RnfH family Ubiquitin; A member of the RnfH family of the ubiquitin superfamily. Members of this family strongly co-occur in two distinct gene neighborhood contexts. In one it is associated with a START domain protein, a membrane protein SmpA and the transfer mRNA binding protein SmpB. This association suggests a possible role in the SmpB-tmRNA-based tagging and degadation system of bacteria, which is interesting given that other members of the ubiquitin system are analogously involved in protein-tagging and degradation across eukaryotes and various prokaryotes. The second context in which the RnfH genes are present is in a membrane associated complex involved in transporting electrons for various reductive reactions such as nitrogen fixation.


Pssm-ID: 427429  Cd Length: 83  Bit Score: 75.16  E-value: 3.56e-20
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 1591805117  7 KNKLGIYSRPVKLHDEVHDGDRVEIYRPLIADPKELRR 44
Cdd:pfam03658 46 TNKVGIFGKLVKLDTVLRDGDRVEIYRPLIADPKEARR 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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