NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2430284114|gb|WBY65495|]
View 

NADH dehydrogenase subunit 2, partial (mitochondrion) [Nephrurus asper]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 12-313 6.12e-117

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 340.65  E-value: 6.12e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  12 ATGTIITLSSEHWLLAWAGVELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLSLPG 91
Cdd:MTH00112   14 ILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQWDITQLTNPT 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  92 ANTILTLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAPALLLYMTTNNLDKNTLIALGLLSSTLGGWLGLNQT 171
Cdd:MTH00112   94 SCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLNQT 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 172 QTRKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTTWPQAPTLLFITMLIL*SLGG 251
Cdd:MTH00112  174 QLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAG 253

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2430284114 252 LPPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSYITTLTLPPGTTNSKHQW 313
Cdd:MTH00112  254 LPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKW 315
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 12-313 6.12e-117

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 340.65  E-value: 6.12e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  12 ATGTIITLSSEHWLLAWAGVELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLSLPG 91
Cdd:MTH00112   14 ILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQWDITQLTNPT 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  92 ANTILTLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAPALLLYMTTNNLDKNTLIALGLLSSTLGGWLGLNQT 171
Cdd:MTH00112   94 SCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLNQT 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 172 QTRKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTTWPQAPTLLFITMLIL*SLGG 251
Cdd:MTH00112  174 QLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAG 253

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2430284114 252 LPPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSYITTLTLPPGTTNSKHQW 313
Cdd:MTH00112  254 LPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKW 315
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 21-284 1.65e-17

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 80.82  E-value: 1.65e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  21 SEHWLLAWAGVELNTLAIMPLI-SKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLSLPGANTI---- 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  96 -------LTLAIAMKLGLAPFHFWLPEVLQGS-TLFTAFIISTWQKLAPALL-----LYMTTNNLDKNTLIALGLLSSTL 162
Cdd:pfam00361  81 llllfllILVGFLFKSAQVPFHTWLPDAYEGApTPVSALLAATLVKAGGYGLirrslLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 163 GGWLGLNQTQTRKIMAFSSVA----***************************SA*FTTLTT*S-----SKT*SD*GTTWP 233
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSIShmgyMLIALGAGTIYGIQAAIFHLLTHGLFSAGLFLCAGSVIyrrvhTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2430284114 234 QAPTLLFITMLIL*SLGGLPPLTGFAPKFMILKELTTANMTIISTLMALSS 284
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 12-293 5.91e-17

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 80.93  E-value: 5.91e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  12 ATGTIITLSSEHWLLAWAGVELNTLAIMPLIS-KQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLS-- 88
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGIAaa 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  89 ---LPGANTILTLAIAM-------KLGLAPFHFWLPEVLQGS-TLFTAFiISTWQKLAPALLLY------MTTNNLD-KN 150
Cdd:COG1007   192 laaGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGApTPVTAF-LATAPKIAAFAALLrllveaFPGLAADwQL 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 151 TLIALGLLSSTLGGWLGLNQTQTRKIMAFSSVA----***************************SA*FTTLTT*SSKT*S 226
Cdd:COG1007   271 LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAhagyLLLGLAAGTPLGVSAALFYLLAYLFMNLGAFAVILLLSRKGGE 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2430284114 227 D*------GTTWpQAPTLLFITMLIL*SLGGLPPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLR 293
Cdd:COG1007   351 AEeiedlaGLAR-RSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 13-293 4.58e-15

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 75.37  E-value: 4.58e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  13 TGTIITLSSEHWLLAWAGVELNTLAIMPLIS-KQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDI-----FQ 86
Cdd:TIGR01770 113 LGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFedlllFL 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  87 LSLPGANTILTL-------AIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLA---PALLLYMTT----NNLDKNTL 152
Cdd:TIGR01770 193 SNGMLNISLLLLgivlilvGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYIlfgfSEAWQIFL 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 153 IALGLLSSTLGGWLGLNQTQTRKIMAFSSVA***************************sA*FTTLTT*SSKT*SD*GTTW 232
Cdd:TIGR01770 273 AIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIY-ALMSLGAFGVLSLLRSYKDEW 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2430284114 233 PQ-----------APTLLFITMLIL*SLGGLPPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLR 293
Cdd:TIGR01770 352 IEyisdfaglfktNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 12-313 6.12e-117

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 340.65  E-value: 6.12e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  12 ATGTIITLSSEHWLLAWAGVELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLSLPG 91
Cdd:MTH00112   14 ILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQWDITQLTNPT 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  92 ANTILTLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAPALLLYMTTNNLDKNTLIALGLLSSTLGGWLGLNQT 171
Cdd:MTH00112   94 SCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLNQT 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 172 QTRKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTTWPQAPTLLFITMLIL*SLGG 251
Cdd:MTH00112  174 QLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAG 253

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2430284114 252 LPPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSYITTLTLPPGTTNSKHQW 313
Cdd:MTH00112  254 LPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKW 315
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 12-313 8.75e-108

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 317.25  E-value: 8.75e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  12 ATGTIITLSSEHWLLAWAGVELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLSLPG 91
Cdd:MTH00070   14 ALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWFTGEWTIMNMQTPL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  92 ANTILTLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAPALLLYMTTNNLDKNTLIALGLLSSTLGGWLGLNQT 171
Cdd:MTH00070   94 PTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLLSTLIGGWGGLNQT 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 172 QTRKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTTWPQAPTLLFITMLIL*SLGG 251
Cdd:MTH00070  174 QLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTLLSLGG 253

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2430284114 252 LPPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSYITTLTLPPGTTNSKHQW 313
Cdd:MTH00070  254 LPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYW 315
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 14-296 1.80e-104

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 309.04  E-value: 1.80e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  14 GTIITLSSEHWLLAWAGVELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLSLPGAN 93
Cdd:MTH00135   16 GTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWDIQQMSHPLPT 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  94 TILTLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAP-ALLLYMTTNNldKNTLIALGLLSSTLGGWLGLNQTQ 172
Cdd:MTH00135   96 TMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPfALILQIAPTN--PTLLITLGLTSTLVGGWGGLNQTQ 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 173 TRKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTTWPQAPTLLFITMLIL*SLGGL 252
Cdd:MTH00135  174 LRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGL 253

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 2430284114 253 PPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSY 296
Cdd:MTH00135  254 PPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSY 297
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 13-313 3.13e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 280.19  E-value: 3.13e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  13 TGTIITLSSEHWLLAWAGVELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLSLPGA 92
Cdd:MTH00105   15 LGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGQWTITKLTNPTA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  93 NTILTLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAPALLLYMTTNNLDKNTLIALGLLSSTLGGWLGLNQTQ 172
Cdd:MTH00105   95 STLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILSILIGGWGGLNQTQ 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 173 TRKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTTWPQAPTLLFITMLIL*SLGGL 252
Cdd:MTH00105  175 LRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLSLGGL 254

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2430284114 253 PPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSYITTLTLPPGTTNSKHQW 313
Cdd:MTH00105  255 PPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKW 315
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 14-313 5.27e-76

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 236.40  E-value: 5.27e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  14 GTIITLSSEHWLLAWAGVELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLSLPGAN 93
Cdd:MTH00200   16 GTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQWGISEMLGPLSE 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  94 TILTLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAPALLLYMTTNNLDKNTLIALGLLSSTLGGWLGLNQTQT 173
Cdd:MTH00200   96 TLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLLSVLVGGWGGLNQTQL 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 174 RKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTTWPQAPTLLFITMLIL*SLGGLP 253
Cdd:MTH00200  176 RKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLLGLTLLSLGGLP 255

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 254 PLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSYITTLTLPPGTTNSKHQW 313
Cdd:MTH00200  256 PLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSW 315
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 14-296 3.71e-73

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 229.05  E-value: 3.71e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  14 GTIITLSSEHWLLAWAGVELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLSLPGAN 93
Cdd:MTH00041   16 GTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPLNTLSS 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  94 TILTLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAPALLLYMTTNNLDKNTLIALGLLSSTLGGWLGLNQTQT 173
Cdd:MTH00041   96 IIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGLNQTQT 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 174 RKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTTWPQAPTLLFITMLIL*SLGGLP 253
Cdd:MTH00041  176 RKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLP 255

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 2430284114 254 PLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSY 296
Cdd:MTH00041  256 PLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISF 298
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 13-296 9.61e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 168.08  E-value: 9.61e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  13 TGTIITLSSEHWLLAWAGVELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFqlslpgA 92
Cdd:MTH00160   16 MGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLMLFNNI------S 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  93 NTILTLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAPALLLYMTTNNldkNTLIALGLLSSTLGGWLGLNQTQ 172
Cdd:MTH00160   90 SMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINN---NFIIIIIILSAIIGAIGGLNQTS 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 173 TRKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTTWPQAPTLLFITMLIL*SLGGL 252
Cdd:MTH00160  167 LRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGL 246

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 2430284114 253 PPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSY 296
Cdd:MTH00160  247 PPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISY 290
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 13-297 7.07e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 165.83  E-value: 7.07e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  13 TGTIITLSSEHWLLAWAGVELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFqlslpga 92
Cdd:MTH00144   15 MGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM------- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  93 nTILTLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAP-ALLLYMTTNNLDKNTLIALGLLSSTLGGWLGLNQT 171
Cdd:MTH00144   88 -SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPlFLLSNFLDLYWLAYLLCVISVLSALVGSIGGLNQT 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 172 QTRKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTTWPQAPTLLFITMLIL*SLGG 251
Cdd:MTH00144  167 QVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISLLL-SLGG 245

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 2430284114 252 LPPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSYI 297
Cdd:MTH00144  246 LPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFS 291
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 13-294 1.69e-38

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 138.76  E-value: 1.69e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  13 TGTIITLSSEHWLLAWAGVELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLnawktgQWDIFQLSLPGA 92
Cdd:MTH00011   17 LGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTM------MWSFPSLLKNIT 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  93 NTILTLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAPALLLYMTTNNLDKNTLIALGLLSSTLGGWLGLNQTQ 172
Cdd:MTH00011   91 ALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMNQTQ 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 173 TRKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTTWPQAPTLLFITMLIL*SLGGL 252
Cdd:MTH00011  171 LRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGL 250

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 2430284114 253 PPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRM 294
Cdd:MTH00011  251 PPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNL 292
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 13-296 1.53e-32

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 122.86  E-value: 1.53e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  13 TGTIITLSSEHWLLAWAGVELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLNawktgQWDIFQLSLpgA 92
Cdd:MTH00197    9 GGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLS-----FSNLYLSLL--S 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  93 NTILTLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAPALLLYMTTNNLDknTLIALGLLSSTLGGWLGLNQTQ 172
Cdd:MTH00197   82 VVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFM--GLLICSVLSSLIGGIGGMNQSN 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 173 TRKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTTWPQAPTLLFITMLIL*SLGGL 252
Cdd:MTH00197  160 IRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGL 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 2430284114 253 PPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSY 296
Cdd:MTH00197  240 PPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAY 283
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 21-284 1.65e-17

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 80.82  E-value: 1.65e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  21 SEHWLLAWAGVELNTLAIMPLI-SKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLSLPGANTI---- 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  96 -------LTLAIAMKLGLAPFHFWLPEVLQGS-TLFTAFIISTWQKLAPALL-----LYMTTNNLDKNTLIALGLLSSTL 162
Cdd:pfam00361  81 llllfllILVGFLFKSAQVPFHTWLPDAYEGApTPVSALLAATLVKAGGYGLirrslLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 163 GGWLGLNQTQTRKIMAFSSVA----***************************SA*FTTLTT*S-----SKT*SD*GTTWP 233
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSIShmgyMLIALGAGTIYGIQAAIFHLLTHGLFSAGLFLCAGSVIyrrvhTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2430284114 234 QAPTLLFITMLIL*SLGGLPPLTGFAPKFMILKELTTANMTIISTLMALSS 284
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 12-293 5.91e-17

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 80.93  E-value: 5.91e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  12 ATGTIITLSSEHWLLAWAGVELNTLAIMPLIS-KQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLS-- 88
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGIAaa 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  89 ---LPGANTILTLAIAM-------KLGLAPFHFWLPEVLQGS-TLFTAFiISTWQKLAPALLLY------MTTNNLD-KN 150
Cdd:COG1007   192 laaGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGApTPVTAF-LATAPKIAAFAALLrllveaFPGLAADwQL 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 151 TLIALGLLSSTLGGWLGLNQTQTRKIMAFSSVA----***************************SA*FTTLTT*SSKT*S 226
Cdd:COG1007   271 LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAhagyLLLGLAAGTPLGVSAALFYLLAYLFMNLGAFAVILLLSRKGGE 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2430284114 227 D*------GTTWpQAPTLLFITMLIL*SLGGLPPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLR 293
Cdd:COG1007   351 AEeiedlaGLAR-RSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 13-293 4.58e-15

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 75.37  E-value: 4.58e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  13 TGTIITLSSEHWLLAWAGVELNTLAIMPLIS-KQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDI-----FQ 86
Cdd:TIGR01770 113 LGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFedlllFL 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  87 LSLPGANTILTL-------AIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLA---PALLLYMTT----NNLDKNTL 152
Cdd:TIGR01770 193 SNGMLNISLLLLgivlilvGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYIlfgfSEAWQIFL 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 153 IALGLLSSTLGGWLGLNQTQTRKIMAFSSVA***************************sA*FTTLTT*SSKT*SD*GTTW 232
Cdd:TIGR01770 273 AIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIY-ALMSLGAFGVLSLLRSYKDEW 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2430284114 233 PQ-----------APTLLFITMLIL*SLGGLPPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLR 293
Cdd:TIGR01770 352 IEyisdfaglfktNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-293 2.32e-14

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 73.32  E-value: 2.32e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  14 GTIITLSSEHWLLAWAGVELNTLAIMPLIS-KQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLSL--- 89
Cdd:PRK05777  115 GMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKala 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  90 --PGANTILTLAIAM-------KLGLAPFHFWLPEVLQGS-TLFTAFiISTWQKLA---PAL-LLYMTTNNLD---KNTL 152
Cdd:PRK05777  195 dgSGNSLLLLFGLVFllvglafKLSAVPFHMWTPDVYEGApTPVTAF-LATAPKIAafaVLLrLLVVAFGGLSedwQQVL 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 153 IALGLLSSTLGGWLGLNQTQTRKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTTW 232
Cdd:PRK05777  274 AIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLFMTLGAFGVISLLRRKGGEAE 353

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 233 P---------QAPTLLFITMLIL*SLGGLPPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLR 293
Cdd:PRK05777  354 SisdfaglskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLR 423
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 12-183 2.65e-14

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 72.37  E-value: 2.65e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  12 ATGTIITLSSEHWLLAWAGVELNTLAIMPLI-SKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDI------ 84
Cdd:MTH00196    3 ALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLsyinlv 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  85 -------FQLSLPGANTILTLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAPALLLYMTTNNLdkNTLIALGL 157
Cdd:MTH00196   83 lnsgqsfSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNV--NILLIGGL 160

                         170       180
                  ....*....|....*....|....*.
gi 2430284114 158 LSSTLGGWLGLNQTQTRKIMAFSSVA 183
Cdd:MTH00196  161 FSLFVGAIGALNQTKIKRLLAYSGIG 186
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 12-180 2.82e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 66.96  E-value: 2.82e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  12 ATGTIITLSSEHWLLAWAGVELNTLAIMPLIS-KQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQwdifqLSLP 90
Cdd:MTH00199  107 ALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGE-----TSIQ 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  91 GANTIL---------TLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAPALLLYMTtnNLDKNTLIALGLLSST 161
Cdd:MTH00199  182 GINSILtgdvgkiliTISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQI--GPVTNVVLICAVLSII 259

                         170
                  ....*....|....*....
gi 2430284114 162 LGGWLGLNQTQTRKIMAFS 180
Cdd:MTH00199  260 YGAIGALNQTKIKRLLAYS 278
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 14-182 6.03e-09

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 56.79  E-value: 6.03e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  14 GTIITLSSEHWLLAWAGVELNTLAIMPLISKQHHPRAT---------EAATKYFLTQATASTLIIFASSLNAWKTGQ--- 81
Cdd:MTH00198  200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNegm 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  82 -WDIFQLSLPGANTIL----------TLAIAMKLGLAPFHFWLPEVLQGSTLFTAFIISTWQKLAPALLLymTTNNLDKN 150
Cdd:MTH00198  280 lGTILSATLETTNIELrqgslgylfiTVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILL--TSLVITSK 357

                         170       180       190
                  ....*....|....*....|....*....|..
gi 2430284114 151 TLIALGLLSSTLGGWLGLNQTQTRKIMAFSSV 182
Cdd:MTH00198  358 LLLSVAIISLVVGAFGALNQTRIKRLLAYSGI 389
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 28-297 6.75e-09

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 56.31  E-value: 6.75e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  28 WAGVELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLSLPGAN----------TILT 97
Cdd:COG0651   133 FVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLAEldpglllaafALLL 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  98 LAIAMKLGLAPFHFWLPE-----------VLQGSTLFTAF--IISTWQKLAPALLLYMTTnnldkNTLIALGLLSSTLGG 164
Cdd:COG0651   213 VGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALFLG-----TLLLVLGLLTMLVGA 287

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 165 WLGLNQTQTRKIMAFSSVA----***************************SA*F----TTLTT*SSKT*SD*GTTWPQAP 236
Cdd:COG0651   288 LGALAQRDLKRLLAYSSVSqigyILLGLGLGTPLGLAGALFHLLNHALAKALLFlaagAIERATGTRDLDKLGGLGKRMP 367

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2430284114 237 TLLFITMLIL*SLGGLPPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSYI 297
Cdd:COG0651   368 LTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGR 428
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
48-183 3.56e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 51.21  E-value: 3.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  48 PRATEAATKYFLTQATASTLIIFASSL----NAWKTGQWDIFQLSLPGANTILTLA-------IAMKLGLAPFHFWLPEV 116
Cdd:PRK02504  157 PRSNEAALKYLLIGAASSAIFLYGSSLlyglSGGSTQLSAIALALITSPSLGLALAlvfviagIAFKISAVPFHQWTPDV 236

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2430284114 117 LQGS-TLFTAFiISTWQKLAP-AL---LLYMTTNNLD---KNTLIALGLLSSTLGGWLGLNQTQTRKIMAFSSVA 183
Cdd:PRK02504  237 YEGSpTPVVAF-LSVGSKAAGfALairLLVTAFPSFDeqwKLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIG 310
ndhB CHL00049
NADH dehydrogenase subunit 2
 49-183 1.37e-04

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 43.45  E-value: 1.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  49 RATEAATKYFLTQATASTLIIFASS----LNAWKTGQWDI------FQLSLPGANTI----LTLAIAMKLGLAPFHFWLP 114
Cdd:CHL00049  159 RSNEATMKYLLMGGASSSILVYGFSwlygLSGGEIELQEIvnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTP 238

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2430284114 115 EVLQGS-TLFTAFIISTWQKLAPAL------LLYMTTNNLDKNTLIALGLLSSTLGGWLGLNQTQTRKIMAFSSVA 183
Cdd:CHL00049  239 DVYEGSpTPVVAFLSVTSKVAASALatrifdIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIG 314
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 31-183 1.57e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 42.94  E-value: 1.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  31 VELNTLAIMPLISKQHHPRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIFQLS--LPGANTILT------LAIAM 102
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAgaLAENPTVVTafgfvlLALAL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 103 KLGLAPFHFWLPEVLQGSTLF-TAFIISTWQKLA--PALLLYMTTNNLDKNT-------LIALGLLSSTLGGWLGLNQTQ 172
Cdd:PRK08375  215 KAAVFPLHTWLPRAYPAAPPVvTALLSGLVTKVAvyALIRIYFTVFGGDFRFalglgwlLAVLALLSMLVGSLAALGQDD 294

                         170
                  ....*....|.
gi 2430284114 173 TRKIMAFSSVA 183
Cdd:PRK08375  295 VKRVLAYSTVS 305
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 28-296 1.70e-03

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 39.98  E-value: 1.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  28 WAGVELNTLAIMPLISKqhhpRATEAATKYFLTQATASTLIIFASSLNAWKTGQWDIF-------QLSLPGANTILTLAI 100
Cdd:PRK08668  127 WEIMTFSSFMMVPMGKK----ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFAdisqgliNDTSTGFALIVFLFL 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 101 A----MKLGLAPFHFWLPE-----------VLQGS---------TLFTAFIISTwqKLAPALLLYMTTnNLDKNTLIALG 156
Cdd:PRK08668  203 LafgvAKAGIFPLHVWAPDayseapqsfsaVLSGQlsklgaygfLLVLYVLPGT--KLFSEFGTYRGV-PLFNYILAWLG 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 157 LLSSTLGGWLGLNQTQTRKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTT----- 231
Cdd:PRK08668  280 NISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFAGGLFHVFNHALFKGLFFLIFAAVIYRTGTTkisem 359

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2430284114 232 ----WPQAPTLLFITMLIL*SLGGLPPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSY 296
Cdd:PRK08668  360 ggliEKMPFTFAMYLVAII-SLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLA 427
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 53-183 2.02e-03

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 39.54  E-value: 2.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  53 AATKYFLTQATASTLIIFASSLNAWKTGQW----DIFQLSLP-GANTILTLAI----AMKLGLAPFHFWLPEV-LQGSTL 122
Cdd:TIGR01972 157 AAMKFFLYTLAGSLLMLLAILGLYFLGGGTfdllELLNLPLPfGVQTWLFLAFfiafAVKVPLFPLHTWLPDAhVEAPTA 236

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2430284114 123 FTAFIISTWQKLAP------ALLLYMTTNNLDKNTLIALGLLSSTLGGWLGLNQTQTRKIMAFSSVA 183
Cdd:TIGR01972 237 GSVILAGVLLKMGTygflrfNLPLFPDASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSIS 303
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 46-297 3.71e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 38.80  E-value: 3.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  46 HHPRATEAATKYFLTQATASTLIIFA--------SSLN----AWKTGQWDIFQLSLPGANTILTLAIAM---------KL 104
Cdd:PRK12667  158 DRGDAVEAAIKYALIGAVGTTLYFLAlaflyatfGTLNmadlSAKIRGLSFPLTGGLAGNPPLALGVALalalwaftiKA 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 105 GLAPFHFWLPEV-----------LQG-----------STLFTAFIISTwqKLAPALLLYMTTnnldkntLIALGLLSSTL 162
Cdd:PRK12667  238 AIFPNHFWLPDAhpaapspvsamLSGlvvnvgayaiiRFLYTIFGISP--SLIDFRAALSPI-------LIILGAVSAII 308

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114 163 GGWLGLNQTQTRKIMAFSSVA***************************SA*FTTLTT*SSKT*SD*GTT--------WPQ 234
Cdd:PRK12667  309 GALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIINHAIAKSLLFLASGVFIHAAGTRdidelaglGRK 388

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2430284114 235 APTLLFITMLIL*SLGGLPPLTGFAPKFMILKELTTANMTIISTLMALSSLPSLFFYLRMSYI 297
Cdd:PRK12667  389 MPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 18-182 4.27e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 38.76  E-value: 4.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  18 TLSSEHWLLAWAGVELNTLAIMPLISKQHHPRATEAATKYFL------TQATASTLIIFASSLNAWKTGQWDIFQLSLPG 91
Cdd:PRK06458  124 ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANAATVMGDGEMAILWTELLK 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2430284114  92 AN-----TILTLAIAM-------KLGLAPFHFWLPE-----------VLQGSTLFTA-FIISTWQKLAPALLLYMTTNNL 147
Cdd:PRK06458  204 HAslldpTLMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVAlYAVLRYYILIDAAIGSDFPGRL 283

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2430284114 148 dkntLIALGLLSSTLGGWLGLNQTQTRKIMAFSSV 182
Cdd:PRK06458  284 ----LLIFGLLSVLVAAFFLLRQRDIKRLFAYSSI 314
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH