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Conserved domains on  [gi|2463122512|gb|WES82270|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Zootermopsis angusticollis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 8.78e-82

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 251.67  E-value: 8.78e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512   1 MPNNSTKILLLTTLTSGILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMSal 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILN-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  81 eeSMLTNSNNLYTQMLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLISYQINNDVFLgMIIMSSVM 160
Cdd:MTH00160   79 --MLNLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFII-IIIILSAI 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 161 IGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMALTEKKNKLTKFL 240
Cdd:MTH00160  156 IGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 241 VFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYSSLMILHSETKWLIAQPTNKMPKYI 320
Cdd:MTH00160  236 LFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLIL 315

                         330
                  ....*....|....*...
gi 2463122512 321 ILLTSVSVMGLMMSETIM 338
Cdd:MTH00160  316 NFLSFISLFGLILSSLLF 333
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 8.78e-82

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 251.67  E-value: 8.78e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512   1 MPNNSTKILLLTTLTSGILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMSal 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILN-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  81 eeSMLTNSNNLYTQMLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLISYQINNDVFLgMIIMSSVM 160
Cdd:MTH00160   79 --MLNLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFII-IIIILSAI 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 161 IGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMALTEKKNKLTKFL 240
Cdd:MTH00160  156 IGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 241 VFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYSSLMILHSETKWLIAQPTNKMPKYI 320
Cdd:MTH00160  236 LFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLIL 315

                         330
                  ....*....|....*...
gi 2463122512 321 ILLTSVSVMGLMMSETIM 338
Cdd:MTH00160  316 NFLSFISLFGLILSSLLF 333
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-333 1.02e-28

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 115.43  E-value: 1.02e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEI-NLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMM--------------SALE 81
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLiygftgslnfedllLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  82 ESMLTNSNNLYTQMLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAA---------PLSLISYQINNDVFLG 152
Cdd:TIGR01770 194 NGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifavflrlfLYILFGFSEAWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 153 MIIMSSVMIGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVA----YFTIYSMLTL---TVVSIVKTTKLSFIN 225
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKavlfYIFIYALMSLgafGVLSLLRSYKDEWIE 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 226 QMALTE---KKNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMsySSLMILH 302
Cdd:TIGR01770 354 YISDFAglfKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV--VKVMYFD 431

                         330       340       350
                  ....*....|....*....|....*....|.
gi 2463122512 303 SETKWLIAQPTNKMPKYIILLTSVSVMGLMM 333
Cdd:TIGR01770 432 KPERRIPSNPQSKAQSLLLSISALFILFLGL 462
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-283 2.11e-26

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 105.86  E-value: 2.11e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  24 SNSWFGAWMGLEINLLSFIPMM-VEKKNIYTTEASLKYFIVQAGASSMLLFMVMM-------------SALEESMLTNSN 89
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLmynytgtlsfdelSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  90 NLYTQMLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLIL-MTLQKAAPLSLI-------SYQINNDVFLGMIIMSSVMI 161
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 162 GAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDM----WVAYFTIYSMLTLTVVSIV-----KTTKLSFINQMALTEK 232
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYgiqaAIFHLLTHGLFSAGLFLCAgsviyRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2463122512 233 KNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMS 283
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 17-292 2.04e-23

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 100.19  E-value: 2.04e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEinLLSfIPMMV----EKKNIYTTEASLKYFIVQAGASSMLLF-MVMMSALEESM-LTNSNN 90
Cdd:COG1007   114 GMMLMASANDLLTLFLGLE--LLS-LSLYVlvafRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGATGSLnLAGIAA 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  91 LYTQMLINTPLLL------------KGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAP-------LSLISYQINNDVFL 151
Cdd:COG1007   191 ALAAGGANSPLLLlglvlvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAfaallrlLVEAFPGLAADWQL 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 152 GMIIMS--SVMIGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVA----YFTIYSMLTL---TVVSIVK----- 217
Cdd:COG1007   271 LLAVLAvlSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSaalfYLLAYLFMNLgafAVILLLSrkgge 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2463122512 218 TTKLSFINQMAlteKKNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMR 292
Cdd:COG1007   351 AEEIEDLAGLA---RRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 8.78e-82

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 251.67  E-value: 8.78e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512   1 MPNNSTKILLLTTLTSGILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMSal 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILN-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  81 eeSMLTNSNNLYTQMLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLISYQINNDVFLgMIIMSSVM 160
Cdd:MTH00160   79 --MLNLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFII-IIIILSAI 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 161 IGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMALTEKKNKLTKFL 240
Cdd:MTH00160  156 IGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 241 VFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYSSLMILHSETKWLIAQPTNKMPKYI 320
Cdd:MTH00160  236 LFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLIL 315

                         330
                  ....*....|....*...
gi 2463122512 321 ILLTSVSVMGLMMSETIM 338
Cdd:MTH00160  316 NFLSFISLFGLILSSLLF 333
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 17-338 4.10e-64

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 206.60  E-value: 4.10e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMSALEESM--LTNSNNLYTQ 94
Cdd:MTH00112   16 GTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQwdITQLTNPTSC 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  95 MLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSL---ISYQINNDVFLGMIIMSsVMIGAIGGLNQTS 171
Cdd:MTH00112   96 TLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLllmTSNSLNPTLLLTLAILS-TLIGGWGGLNQTQ 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 172 LRKIMTYSSINHTGWMMSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMALTEKKNKLTKFLVFTSILSLGGL 251
Cdd:MTH00112  175 LRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAGL 254

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 252 PPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYSSLMILHSET-----KWLIAQPTNkmpKYIILLTSV 326
Cdd:MTH00112  255 PPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTtnmmmKWRTKPKKN---TLTATLTTL 331

                         330
                  ....*....|..
gi 2463122512 327 SVMGLMMSETIM 338
Cdd:MTH00112  332 STLLLPLSPMIL 343
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 16-333 7.82e-64

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 205.85  E-value: 7.82e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  16 SGILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMSALEES--MLTNSNNLYT 93
Cdd:MTH00105   15 LGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGqwTITKLTNPTA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  94 QMLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSlISYQINNDVFLGMIIMS---SVMIGAIGGLNQT 170
Cdd:MTH00105   95 STLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLS-ILYQISPSINPNLLLTLailSILIGGWGGLNQT 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 171 SLRKIMTYSSINHTGWMMSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMALTEKKNKLTKFLVFTSILSLGG 250
Cdd:MTH00105  174 QLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLSLGG 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 251 LPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYSSLMILHSETKWLIAQPTNKMPKYIILLTSVSVMG 330
Cdd:MTH00105  254 LPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENTKPMTLLPTLIILS 333


                  ...
gi 2463122512 331 LMM 333
Cdd:MTH00105  334 TML 336
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 17-338 4.34e-63

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 203.88  E-value: 4.34e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMSAL---EESMLTNSNNLYT 93
Cdd:MTH00135   16 GTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWltgQWDIQQMSHPLPT 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  94 QMLInTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLIsYQI--NNDVFLGMIIMSSVMIGAIGGLNQTS 171
Cdd:MTH00135   96 TMIT-LALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALI-LQIapTNPTLLITLGLTSTLVGGWGGLNQTQ 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 172 LRKIMTYSSINHTGWMMSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMALTEKKNKLTKFLVFTSILSLGGL 251
Cdd:MTH00135  174 LRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGL 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 252 PPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYSSLM-----ILHSETKWLIAQPTNKMPkyIILLTSV 326
Cdd:MTH00135  254 PPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLtispnTLNGTTPWRLPSTQLTLP--LAISTTA 331

                         330
                  ....*....|..
gi 2463122512 327 SVMGLMMSETIM 338
Cdd:MTH00135  332 TLMLLPLTPAIL 343
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 17-338 6.71e-59

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 193.21  E-value: 6.71e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMSALE--ESMLTNSNNLYTQ 94
Cdd:MTH00070   16 GTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWFtgEWTIMNMQTPLPT 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  95 MLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLIsYQINNDVFLGMII---MSSVMIGAIGGLNQTS 171
Cdd:MTH00070   96 IMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALL-IQISHLLNSNLLIimgLLSTLIGGWGGLNQTQ 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 172 LRKIMTYSSINHTGWMMSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMALTEKKNKLTKFLVFTSILSLGGL 251
Cdd:MTH00070  175 LRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTLLSLGGL 254

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 252 PPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYSSLMILH--SETKWLIAQPTNKMPKYIILLTSVSVM 329
Cdd:MTH00070  255 PPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSpnTSNSKLYWRFKNKTNNLLSLTIILSLM 334


                  ....*....
gi 2463122512 330 GLMMSETIM 338
Cdd:MTH00070  335 LLPITPTIL 343
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 16-301 9.50e-56

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 185.13  E-value: 9.50e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  16 SGILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMSA-LEESMLTNSN-NLYT 93
Cdd:MTH00041   15 LGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAwLSGSWSINGPlNTLS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  94 QMLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLISYqINNDVFLGMII---MSSVMIGAIGGLNQT 170
Cdd:MTH00041   95 SIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLIS-ISNLLNSNILIlcgILSVLVGGWGGLNQT 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 171 SLRKIMTYSSINHTGWMMSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMALTEKKNKLTKFLVFTSILSLGG 250
Cdd:MTH00041  174 QTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGG 253

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2463122512 251 LPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYSSLMIL 301
Cdd:MTH00041  254 LPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTL 304
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 17-338 5.87e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 182.86  E-value: 5.87e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMSALEESM--LTNSNNLYTQ 94
Cdd:MTH00200   16 GTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQwgISEMLGPLSE 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  95 MLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLIS--YQINNDVFLGMIIMSSVMIGAIGGLNQTSL 172
Cdd:MTH00200   96 TLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGLLSVLVGGWGGLNQTQL 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 173 RKIMTYSSINHTGWMMSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMALTEKKNKLTKFLVFTSILSLGGLP 252
Cdd:MTH00200  176 RKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLLGLTLLSLGGLP 255

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 253 PFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYSSLMIL-----HSETKWLIAQPTNkmpKYIILLTSVS 327
Cdd:MTH00200  256 PLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLspnqiNMMSSWRTKSNSN---LLVGLLLLLS 332

                         330
                  ....*....|.
gi 2463122512 328 VMGLMMSETIM 338
Cdd:MTH00200  333 ILGLPLTPQLL 343
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 17-334 1.62e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 175.84  E-value: 1.62e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMsaleesMLTNSNNLYTQML 96
Cdd:MTH00144   16 GTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLI------MYNLSFSWFSMSL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  97 INTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLISYQINNDVFLGMIIMSSVM---IGAIGGLNQTSLR 173
Cdd:MTH00144   90 LLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISVLsalVGSIGGLNQTQVR 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 174 KIMTYSSINHTGWMMSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMaLTEKKNKLTKFLVFTSILSLGGLPP 253
Cdd:MTH00144  170 ALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDL-GSLKPSYKTGLSIISLLLSLGGLPP 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 254 FLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYSSLMilhSETKWLIAQPTNKMPKYIILLTSVSVMGLMM 333
Cdd:MTH00144  249 FLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFL---SSSKSKKSNSSKVLNSSIISLNLLGGLLFLL 325


                  .
gi 2463122512 334 S 334
Cdd:MTH00144  326 L 326
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 17-333 7.82e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 174.09  E-value: 7.82e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMSALEESMLTNSNnlytqML 96
Cdd:MTH00197   10 GVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYLSLLSV-----VL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  97 INTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLISYQINNDVFLGMIIMSSVMIGAIGGLNQTSLRKIM 176
Cdd:MTH00197   85 VILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQSNIRQLL 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 177 TYSSINHTGWMMSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMALTEKKNKLTKFLVFTSILSLGGLPPFLG 256
Cdd:MTH00197  165 AYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGLPPLSG 244

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2463122512 257 FMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYSSLMILHSETKWLIAQPTNKMPKYIILLTSVSVMGLMM 333
Cdd:MTH00197  245 FFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGLFILLMMMLPLLMIFT 321
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 17-300 3.04e-45

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 157.25  E-value: 3.04e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMSALEESMLTNsnnlYTQML 96
Cdd:MTH00011   18 GTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSLLKN----ITALM 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  97 INTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLISY--QINNDVFLGMIIMSSVMIGAIGGLNQTSLRK 174
Cdd:MTH00011   94 LLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFftSHNILPMMTSMAAMSALAGGLGGMNQTQLRP 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 175 IMTYSSINHTGWMMSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMALTEKKNKLTKFLVFTSILSLGGLPPF 254
Cdd:MTH00011  174 LLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLPPF 253

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 2463122512 255 LGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYSSLMI 300
Cdd:MTH00011  254 TGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYL 299
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-333 1.02e-28

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 115.43  E-value: 1.02e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEI-NLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMM--------------SALE 81
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLiygftgslnfedllLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  82 ESMLTNSNNLYTQMLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAA---------PLSLISYQINNDVFLG 152
Cdd:TIGR01770 194 NGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifavflrlfLYILFGFSEAWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 153 MIIMSSVMIGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVA----YFTIYSMLTL---TVVSIVKTTKLSFIN 225
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKavlfYIFIYALMSLgafGVLSLLRSYKDEWIE 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 226 QMALTE---KKNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMsySSLMILH 302
Cdd:TIGR01770 354 YISDFAglfKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV--VKVMYFD 431

                         330       340       350
                  ....*....|....*....|....*....|.
gi 2463122512 303 SETKWLIAQPTNKMPKYIILLTSVSVMGLMM 333
Cdd:TIGR01770 432 KPERRIPSNPQSKAQSLLLSISALFILFLGL 462
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 17-333 1.76e-27

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 110.51  E-value: 1.76e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEINLLSFIPMMVEKKN-IYTTEASLKYFIVQAGASSMLLFMVMM---------SALEESMLT 86
Cdd:MTH00196    5 GILCLISSSNWLSVYLAIELQTLSLFILIAQNRGsGYSAEAGLKYFVLGALSSGLFLFGCALlcgttgglhLSYINLVLN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  87 NSNNLYTQM------LINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLISYQINNDVFLGMIIMSSVM 160
Cdd:MTH00196   85 SGQSFSSVSvpigylLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSLF 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 161 IGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGS----DMWVAYFTIYSMLTLTVVSIVKT--TKLSFINQMALTEKKN 234
Cdd:MTH00196  165 VGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFSIILAlnVYKNLIIEFSGLSRRL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 235 KLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMR----MSYSSLMILHSETKWLIA 310
Cdd:MTH00196  245 PILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRivkiLFFQANSFLLISTKILKK 324

                         330       340
                  ....*....|....*....|...
gi 2463122512 311 QPTNKMPKYIILLTSVSVMGLMM 333
Cdd:MTH00196  325 ENKINLRKALLIGFSLYLILFTI 347
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-283 2.11e-26

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 105.86  E-value: 2.11e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  24 SNSWFGAWMGLEINLLSFIPMM-VEKKNIYTTEASLKYFIVQAGASSMLLFMVMM-------------SALEESMLTNSN 89
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLmynytgtlsfdelSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  90 NLYTQMLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLIL-MTLQKAAPLSLI-------SYQINNDVFLGMIIMSSVMI 161
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 162 GAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDM----WVAYFTIYSMLTLTVVSIV-----KTTKLSFINQMALTEK 232
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYgiqaAIFHLLTHGLFSAGLFLCAgsviyRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2463122512 233 KNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMS 283
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 17-293 7.43e-25

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 104.33  E-value: 7.43e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEINLLS-FIPMMVEKKNIYTTEASLKYFIVQAGASSMLLF---MVMMSALEESMLTNSNNLY 92
Cdd:MTH00199  109 GSLLLVSSINWLSIYLAIELQTLTlFILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFgcaLLYGLTGETSIQGINSILT 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  93 T---QMLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLIsYQI---NNDVFLGMIImsSVMIGAIGG 166
Cdd:MTH00199  189 GdvgKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSIL-VQIgpvTNVVLICAVL--SIIYGAIGA 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 167 LNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVA----YFTIYSMLTLTVVSIVKTTKLS--FINQMALTEKKNKLTKFL 240
Cdd:MTH00199  266 LNQTKIKRLLAYSGIGHMGFILFGVAIGSFESIQasliYMIIYVIMSICSFSIILSLKLTkgLIVEVSGLSRKNPVIALT 345

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2463122512 241 VFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRM 293
Cdd:MTH00199  346 LALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 17-292 2.04e-23

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 100.19  E-value: 2.04e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEinLLSfIPMMV----EKKNIYTTEASLKYFIVQAGASSMLLF-MVMMSALEESM-LTNSNN 90
Cdd:COG1007   114 GMMLMASANDLLTLFLGLE--LLS-LSLYVlvafRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGATGSLnLAGIAA 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  91 LYTQMLINTPLLL------------KGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAP-------LSLISYQINNDVFL 151
Cdd:COG1007   191 ALAAGGANSPLLLlglvlvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAfaallrlLVEAFPGLAADWQL 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 152 GMIIMS--SVMIGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVA----YFTIYSMLTL---TVVSIVK----- 217
Cdd:COG1007   271 LLAVLAvlSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSaalfYLLAYLFMNLgafAVILLLSrkgge 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2463122512 218 TTKLSFINQMAlteKKNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMR 292
Cdd:COG1007   351 AEEIEDLAGLA---RRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
17-292 7.10e-22

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 96.04  E-value: 7.10e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEI-NLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLF-MVMMSALEESM-LTNSNNLYT 93
Cdd:PRK05777  115 GMMVMVSANDLLTLFLGLELlSLPLYALAALRRDRRRSLEAAIKYFVLGALASGFLLYgMSLLYGATGSLsFAGIAKALA 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  94 QMLINTPLLL------------KGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLI---------SYQINNDVFLG 152
Cdd:PRK05777  195 DGSGNSLLLLfglvfllvglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllvvafgGLSEDWQQVLA 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 153 MIIMSSVMIGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVA----YFTIYSMLTL---TVVSIVK-----TTK 220
Cdd:PRK05777  275 IIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSavlfYLLAYLFMTLgafGVISLLRrkggeAES 354

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2463122512 221 LSFINQMAlteKKNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMR 292
Cdd:PRK05777  355 ISDFAGLS---KRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLR 423
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 17-293 8.03e-16

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 77.88  E-value: 8.03e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVM----------MSALEESMLT 86
Cdd:COG0651   119 GMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGllygatgtlnMADLAARLAE 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  87 NSNNLYT--QMLINTPLLLKGGVAPMHWWFPG-----------VMEGLnwnnclilMTlqKAAPLSLI-----SYQINND 148
Cdd:COG0651   199 LDPGLLLaaFALLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGL--------LT--KVGVYAILrvltlLFGADPA 268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 149 VFLGMIIMS----SVMIGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVA---YFTIYSMLT-----LTVVSIV 216
Cdd:COG0651   269 LFLGTLLLVlgllTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAgalFHLLNHALAkallfLAAGAIE 348

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2463122512 217 KTTKLSFINQMALTEKKNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRM 293
Cdd:COG0651   349 RATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 149-296 5.33e-13

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 69.61  E-value: 5.33e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 149 VFLGMIimsSVMIGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVAYFTIY--------SMLTLTVVSIVKTTK 220
Cdd:PRK12667  299 IILGAV---SAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHiinhaiakSLLFLASGVFIHAAG 375

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2463122512 221 LSFINQMALTEKKNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYS 296
Cdd:PRK12667  376 TRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 17-264 2.03e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 64.88  E-value: 2.03e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNSWFGAWMGLEINLLSFIPMMVEK-------KNIYTT--EASLKYFIVQAGASSMLLF-------------- 73
Cdd:MTH00198  200 GGLLLIESANWLTIYLALEFQTLALFILAGEGsqpgshfPSPGNTppESGLKYWILGAMSSGFYLFgcalyfgftgnegm 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  74 --MVMMSALEESMLTNSNNLYTQMLINTPLLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLISYQINNDVFL 151
Cdd:MTH00198  280 lgTILSATLETTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKLL 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 152 GMIIMSSVMIGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGS-----DMWvAYFTIYSMLTLTVVSIV---------- 216
Cdd:MTH00198  360 LSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTyeslqASW-TYAVTYLVSALASFTVIctleefgtrt 438

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2463122512 217 -----KTTKLSFIN------QMALTEKKNKLTKFLVFTSILSLGGLPPFLGFMPKWMII 264
Cdd:MTH00198  439 ptsrqRDGSFGNYNlvrrlvDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFIL 497
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 34-295 5.98e-11

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 63.36  E-value: 5.98e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  34 LEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLF-MVM---------MSALEESMLTNSNNLYTQMLINTPLLL 103
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIgVGLlygvtgtlnMADLAGALAENPTVVTAFGFVLLALAL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 104 KGGVAPMHWWFPG--------VMeglnwnnCLILMTLQKAAPLSLI----------SYQINNDVFLGMIIMS-SVMIGAI 164
Cdd:PRK08375  215 KAAVFPLHTWLPRaypaappvVT-------ALLSGLVTKVAVYALIriyftvfggdFRFALGLGWLLAVLALlSMLVGSL 287

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 165 GGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVAYFTIYSM--------LTLTVVSIVKTTKLSFINQMALTEKKNKL 236
Cdd:PRK08375  288 AALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLLhhalmkgaLFLAAGAIEVTYGTRRLSELSGLGRRMPL 367

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2463122512 237 TKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSY 295
Cdd:PRK08375  368 TAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 150-295 1.48e-09

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 59.24  E-value: 1.48e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 150 FLGMIimsSVMIGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVA--YFTIYS------MLTLTVVSIVKTTKL 221
Cdd:PRK08668  277 WLGNI---SIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFAggLFHVFNhalfkgLFFLIFAAVIYRTGT 353

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2463122512 222 SFINQMALTEKKNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSY 295
Cdd:PRK08668  354 TKISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLA 427
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
149-292 5.84e-09

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 57.27  E-value: 5.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 149 VFLGMIIMssvMIGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVA---YFTIYSM-----LTLTVVSIVKTTK 220
Cdd:PRK12663  276 ATMAAITM---VIGALGALAYKDIRRIAGYQVISSIGFILLGLALGTPAGINgaiFYLVHDMvvktaLFLIAGSLVRLTG 352

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2463122512 221 LSFINQMALTEKKNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMR 292
Cdd:PRK12663  353 YRSLQYLGGLYRKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFR 424
ndhB CHL00049
NADH dehydrogenase subunit 2
 48-292 6.76e-09

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 56.94  E-value: 6.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  48 KKNIYTTEASLKYFIVQAGASSMLLFMV---------------MMSALEESMLTNSNNLYTQM-LINTPLLLKGGVAPMH 111
Cdd:CHL00049  155 KKDVRSNEATMKYLLMGGASSSILVYGFswlyglsggeielqeIVNGLINTQMYNSPGISIALiFITVGIGFKLSLAPFH 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 112 WWFPGVMEGLNWNNCLILMTLQKAAPLSL-------ISYQINND--VFLGMIIMSSVMIGAIGGLNQTSLRKIMTYSSIN 182
Cdd:CHL00049  235 QWTPDVYEGSPTPVVAFLSVTSKVAASALatrifdiPFYFSSNEwhLLLEILAILSMILGNLIAITQTSMKRMLAYSSIG 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 183 HTGWMMSAMITG------SDMWVaYFTIYSMLTL----TVVSIVKTTKLSFINQMALTEKKNKLTKFLVFTSILSLGGLP 252
Cdd:CHL00049  315 QIGYVIIGIIVGdsndgyASMIT-YMLFYIFMNLgtfaCIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGIP 393

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 2463122512 253 PFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMR 292
Cdd:CHL00049  394 PLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLK 433
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 55-331 7.62e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 56.64  E-value: 7.62e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  55 EASLKYFIVQAGASSMLLFMV----------MMSALEESMLTNSNNL--YTQMLINTPLLLKGGVAPMHWWFPGVMEGLN 122
Cdd:PRK08376  172 EAGIKYMFVGSLASSMVLLGIallygqygtlNMAYLAVKMSENPTVVakIALALFIAGLAMKSGAVPVHMWLPDAYPAAP 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 123 WNNCLILMTLQKAAPLSL--ISYQINNDVF----LGMIIM----SSVMIGAIGGLNQTSLRKIMTYSSINHTGWM----- 187
Cdd:PRK08376  252 SSISAMLLVIKQAGLYALarVLFSIYGPAInlatVGWVIIilgcLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMllglg 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 188 ---------------MSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMALTEKKNKLTKFLVFTSILSLGGLP 252
Cdd:PRK08376  332 vglaalgdpamasygEIALAGGIYHIVNHALYKALLFLTAGAVIYETGTRNLNELGGLARTMPKTTIAFLIGAAAIVGLP 411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 253 PFLGFMPKWMIIQTM-MTNDMKTTATMMVlmSVVTLYYYMRMSYSSLMILHSETKWLIAQPTNKMPKYIILLT-SVSVMG 330
Cdd:PRK08376  412 PFNGFASKWLIYESSaLFNPILGVIAMIG--SVLTLASFVKVFHTAFFGPPSEKVMNVKEPPKPMLVPMLILAiAIIGMG 489


                  .
gi 2463122512 331 L 331
Cdd:PRK08376  490 L 490
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
48-292 1.08e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 56.21  E-value: 1.08e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  48 KKNIYTTEASLKYFIVqaGASSMLLFMVMMSALE--ESMLTNSNNLYTQMLINTPLLLK-------GGVA------PMHW 112
Cdd:PRK02504  154 KRDPRSNEAALKYLLI--GAASSAIFLYGSSLLYglSGGSTQLSAIALALITSPSLGLAlalvfviAGIAfkisavPFHQ 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 113 WFPGVMEGLNWNNCLILMTLQKAAPLSL------ISYQINND----VFLGMIIMSSVMiGAIGGLNQTSLRKIMTYSSIN 182
Cdd:PRK02504  232 WTPDVYEGSPTPVVAFLSVGSKAAGFALairllvTAFPSFDEqwklLFTALAILSMVL-GNVVALAQTSMKRMLAYSSIG 310

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 183 HTGWMMSAMITGSD----MWVAYFTIYSMLTLTVVSIVK----TTKLSFINQMALTEKKNKLTKFLVFTSILSLGGLPPF 254
Cdd:PRK02504  311 QAGFVMIGLVAGTEagyaSMVFYLLAYLFMNLGAFACVIlfslRTGTDQISDYAGLYQKDPLLTLGLSLCLLSLGGIPPL 390

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 2463122512 255 LGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMR 292
Cdd:PRK02504  391 AGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIR 428
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 150-292 7.07e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 47.64  E-value: 7.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 150 FLGMIIMSSVMIGAIGGLNQTSLRKIMTYSSINHTGWMMS--AMITGSDMWVA-YFTIYSM-----LTLTVVSIVKTTKL 221
Cdd:PRK07691  277 LILILALLTIIFGVIGAVAYFDIKKIIIYNIMIAVGVILVgvAMMTESGMIGAiYYLIHDMivkaaLFLLIGIMIKITGT 356

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2463122512 222 SFINQMALTEKKNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMR 292
Cdd:PRK07691  357 TDLKKMGGLIKRYPVLGWMFFIAALSLAGIPPLSGFYGKFFIVEGTFEAGFYVSGIIVLLSSLLVLYSVIK 427
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 38-285 7.79e-06

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 47.42  E-value: 7.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  38 LLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMSALEESMLTNSNNLYTQMLINTPLLL-------KGGVAPM 110
Cdd:PRK08667  145 LSSFFLVMNDYQEEETQRAGIFYFVMTQLSTVFLMLGIIVLFIQTGSFELSPLGASAGILSLVFLLlflgfgiKAGIIPF 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 111 HWWFPGVMEGLNWN-NCLILMTLQKAAPLSLISYQIN---NDVFLGMII----MSSVMIGAIGGLNQTSLRKIMTYSSIN 182
Cdd:PRK08667  225 HKWLPYAHPASPSNvSALMSGVMLKVAVYGLVRFLMDvlsPELWWGVLIllagSISALLGVIYALKEHDLKGLLAYSSIE 304

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 183 HTGWMMsamiTGSDMWVAyFTIY------------------------SMLTLTVVSIVKTTKLSFINQMALTEKKNKLTK 238
Cdd:PRK08667  305 NIGIIL----MGIGLYVI-FGVYgldtlallalggalfhslnhalfkSLLFLTAGSVVHATGTRNIEKMGGLVKLMPYTS 379

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 2463122512 239 FLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVV 285
Cdd:PRK08667  380 ALFLVGAVSIAALPPFNGFASELLLYESFFQSFSVADPLIKILLFSV 426
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
151-296 1.90e-05

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 46.18  E-value: 1.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 151 LGMIImssvmiGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVA--------YFTIYSMLTLTVVSIVKTTKLS 222
Cdd:PRK06277  275 LAMVF------GVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIVagifhainHVIYKSALFLGAGIVSYRTKTS 348

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2463122512 223 FINQMALTEKKNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRMSYS 296
Cdd:PRK06277  349 NLRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQSKLMLAQAAMQANMPELAIIMIIVSIGTFVSMMKAFYL 422
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 161-307 2.33e-05

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 45.91  E-value: 2.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 161 IGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSdMWVAYFTIY------SMLTLTVVSIVKTTKLSFINQMALTEKKN 234
Cdd:COG1009   288 FAALIALAQTDIKRVLAYSTVSQLGYMFLALGVGA-YVAALFHLLthaffkALLFLGAGSVIHATGTRDIRKMGGLRKKM 366

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2463122512 235 KLTkFLVFT-SILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTA--TMMVLMSVVTLYYYMRMSYsslMILHSETKW 307
Cdd:COG1009   367 PIT-AITFLiGALSLAGIPPFAGFFSKEAILEAALEAGGLGPLllAVALLGAFLTAFYSFRLFF---LVFFGKPRP 438
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 17-286 3.25e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 45.58  E-value: 3.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  17 GILISISSNsWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQAGASSMLLFMVMMSALEE--------SMLTNS 88
Cdd:PRK06589  129 GVLIALSSD-LFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPAVILIYTKtgnldfvsGGLFSK 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  89 NNLYTQMLINTPLLLKGGVAPMHWWFPGVM-----------------EGLNWNNCLILMTLQkaapLSLISYQINNDVFL 151
Cdd:PRK06589  208 NQSIILLLMFIYGIAKTAIFPVHSWLPAAMvahypvsallhavivvkTGLFCIYKILLYIFG----LSYLQRIFAEFNWL 283

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 152 GMIIMSSVMIGAIGGLNQTSLRKIMTYSSINHTGWMM--SAMITGSDMWVAYFTIYS------MLTLTVVSIVKTTKLSF 223
Cdd:PRK06589  284 IFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALlsAFILTPKALGAAILHLVShsfakiCLFYSMGSIYSLKKEDQ 363

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2463122512 224 INQMALTEKKNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVT 286
Cdd:PRK06589  364 VDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLSIIVMLVVIAS 426
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 148-265 4.86e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 44.96  E-value: 4.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 148 DVFLGMIIMSSVMIGAIGGLNQTSLRKIMTYSSINHTGWMM-------SAMITGSDMWVAY-FTIYSMLTLTVVSIVKTT 219
Cdd:PRK12665  273 DTLLMVVALLTMVVGILGAIAQSDIKRLLSFTLVSHIGYMVfgialstVAGLSGAIYYVAHhITVQTTLFLVVGLIERQA 352

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2463122512 220 KLSFINQMALTEKKNKLTKFLVFTSILSLGGLPPFLGFMPKWMIIQ 265
Cdd:PRK12665  353 GSSSLRRLGGLAKASPLLAVLFFVPALNLGGIPPFSGFIGKVALLE 398
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 101-282 1.23e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 39.85  E-value: 1.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 101 LLLKGGVAPMHWWFPGVMEGLNWNNCLILMTLQKAAPLS----LISYQINNDVFLGMIIMSSVMigaiggLNQTSLRKIM 176
Cdd:MTH00091   67 LMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLvllqFFSKNFFFLLLFGLLICFFQM------FLLKSYKNLL 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 177 TYSSINHTGWM-MSAMITGSDMWVAYFTIYSMLTLTVVSIVKTTKLSFINQMALtekknkltkfLVFTSilslggLPPFL 255
Cdd:MTH00091  141 ILSSTESFNWLiLSFFFSFFNVFFLFFYYFLLMLFLIPKFNNVNKLNFVSWETL----------LVFMN------LPFSV 204

                         170       180
                  ....*....|....*....|....*..
gi 2463122512 256 GFMPKWMIIQTMMTNDMKTTATMMVLM 282
Cdd:MTH00091  205 TFFVKIFSLSEILKVLGFFLLFLLFLM 231
PRK06591 PRK06591
putative monovalent cation/H+ antiporter subunit D; Reviewed
 16-293 2.28e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235837 [Multi-domain]  Cd Length: 432  Bit Score: 39.38  E-value: 2.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  16 SGILISISSNSWFGAWMGLEINLLSFIPMMVEKKNIYTTEASLKYFIVQA-GASSMLLFMVMMSALEESMLTNSNNLYTQ 94
Cdd:PRK06591  126 TGYLGMIATNDFFNLYVFIEISALSSYVLIASGNNPKSLIGAFDYLIMGSiGATLILIAIGFLLSITGSLNMTDIAAYLQ 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512  95 MLINTPL------------LLKGGVAPMHWWfpgVMEGLNWNNCLILMTLqkaAPLSLI---------SYQINN------ 147
Cdd:PRK06591  206 EHTNSRIitiaigffligaILKTAFFPMHFW---MMRAYNNTASVILVYL---AGISTIigiyiiykfTYIIIGyetikt 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 148 --DVFLGMIIMSSVMIGAIGGLNQTSLRKIMTYSSINHTGWMMSAMITGSDMWVayftiysMLTLTVVSIVKTTKLSFIN 225
Cdd:PRK06591  280 aiTNFIRPIALATLIIAPYFAYQAKNFKNIIIYSCFTQIGYVFLLYVTENGIII-------LPSLLLADSINKIALFLID 352

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2463122512 226 QMALTEKKNKLtKFLVFTSILSLGGLPPFLGFMPKWMIIQTMMTNDMKTTATMMVLMSVVTLYYYMRM 293
Cdd:PRK06591  353 AYNESYKREPN-KVLIIIAIICSCGLPISPLFFIKVNILELLLTQNLLLDFIIILLSSVGSLFYHYKM 419
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
109-260 7.42e-03

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 38.08  E-value: 7.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 109 PMHWWFPGVMEGLNWNNCLILMTLQKAAPLSLIS--YQINNDVFLGMIIMS-----SVMIGAIGGLNQTSLRKIMTYSSI 181
Cdd:PRK07376  245 PLHVWLPDAMEGPTPISALIHAATMVAAGVFLVArmYPVFEQFPAVMTVIAwtgaiTAFLGASIALTQNDIKKGLAYSTI 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2463122512 182 NHTGWMMSAMITGSD-------MWVAYFTiySMLTLTVVSIVKTTKLSFINQMALTE---------KKNKLTKFLVFTSI 245
Cdd:PRK07376  325 SQLGYMVMAMGCGAYsaglfhlMTHAYFK--AMLFLGSGSVIHGMEEVVGHDPVLAQdmrlmgglrKYMPITAITFLIGC 402

                         170
                  ....*....|....*
gi 2463122512 246 LSLGGLPPFLGFMPK 260
Cdd:PRK07376  403 LAISGIPPFAGFWSK 417
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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