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Conserved domains on  [gi|2545607029|gb|WKF25740|]
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bacterial cytokinesis Z-ring protein FTSZ 1-1-like protein, partial [Rorippa sylvestris]

Protein Classification

FtsZ/tubulin family protein( domain architecture ID 3)

FtsZ/tubulin family protein may be involved in polymer formation, similar to the cell-division GTPase FtsZ or the tubulin-like filament-forming GTPase TubZ

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FtsZ super family cl43059
Cell division GTPase FtsZ [Cell cycle control, cell division, chromosome partitioning];
1-96 7.39e-40

Cell division GTPase FtsZ [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG0206:

Pssm-ID: 439976 [Multi-domain]  Cd Length: 347  Bit Score: 134.47  E-value: 7.39e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2545607029   1 IPGLVNVDFADVKAVMKDSGTAMLGVGVSSSKNRAEEAAEQATLAPLI-GSSIQSATGVVYNITGGKDITLQEVNRVSQV 79
Cdd:COG0206   203 KPGLINLDFADVKTVMSNGGVALMGIGEASGENRAEEAAEKAISSPLLeDVSISGAKGVLVNITGGSDLTLDEVNEAAEI 282

                          90
                  ....*....|....*..
gi 2545607029  80 VTSLADPSANIIFGAVV 96
Cdd:COG0206   283 IQEEADPDANIIFGAVI 299
 
Name Accession Description Interval E-value
FtsZ COG0206
Cell division GTPase FtsZ [Cell cycle control, cell division, chromosome partitioning];
1-96 7.39e-40

Cell division GTPase FtsZ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 439976 [Multi-domain]  Cd Length: 347  Bit Score: 134.47  E-value: 7.39e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2545607029   1 IPGLVNVDFADVKAVMKDSGTAMLGVGVSSSKNRAEEAAEQATLAPLI-GSSIQSATGVVYNITGGKDITLQEVNRVSQV 79
Cdd:COG0206   203 KPGLINLDFADVKTVMSNGGVALMGIGEASGENRAEEAAEKAISSPLLeDVSISGAKGVLVNITGGSDLTLDEVNEAAEI 282

                          90
                  ....*....|....*..
gi 2545607029  80 VTSLADPSANIIFGAVV 96
Cdd:COG0206   283 IQEEADPDANIIFGAVI 299
FtsZ_type1 cd02201
Filamenting temperature sensitive mutant Z, type 1; FtsZ is a GTPase that is similar to the ...
 1-96 1.90e-39

Filamenting temperature sensitive mutant Z, type 1; FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes. FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at the site of bacterial cell division, which is required for constriction of cell membrane and cell envelope to yield two daughter cells.


Pssm-ID: 276961 [Multi-domain]  Cd Length: 303  Bit Score: 132.14  E-value: 1.90e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2545607029   1 IPGLVNVDFADVKAVMKDSGTAMLGVGVSSSKNRAEEAAEQATLAPLIGSSIQSATGVVYNITGGKDITLQEVNRVSQVV 80
Cdd:cd02201   192 KPGLINLDFADVKTVMKNGGLALMGIGEASGENRAEEAVEKALNSPLLEDDIKGAKGVLVNITGGPDLTLEEVNEAAEII 271

                          90
                  ....*....|....*.
gi 2545607029  81 TSLADPSANIIFGAVV 96
Cdd:cd02201   272 TEKADPDANIIFGAVI 287
Tubulin_C smart00865
Tubulin/FtsZ family, C-terminal domain; This domain is found in the tubulin alpha, beta and ...
 5-96 1.12e-30

Tubulin/FtsZ family, C-terminal domain; This domain is found in the tubulin alpha, beta and gamma chains, as well as the bacterial FtsZ family of proteins. These proteins are GTPases and are involved in polymer formation. Tubulin is the major component of microtubules, while FtsZ is the polymer-forming protein of bacterial cell division, it is part of a ring in the middle of the dividing cell that is required for constriction of cell membrane and cell envelope to yield two daughter cells. FtsZ can polymerise into tubes, sheets, and rings in vitro and is ubiquitous in bacteria and archaea. This is the C-terminal domain.


Pssm-ID: 214868 [Multi-domain]  Cd Length: 120  Bit Score: 104.55  E-value: 1.12e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2545607029    5 VNVDFADVKAVMKDSGTAMLGVGVSSSKNRAEEAAEQATLAPLI-GSSIQSATGVVYNITGGKDITLQEVNRVSQVVTSL 83
Cdd:smart00865   1 INVDFADVKTVMVPMGFAMMGIGPASGENRALEAAELAISSPLLeDSNIMGAKGVLVNITGGPDLTLKEVNEAMERIREK 80

                           90
                   ....*....|...
gi 2545607029   84 ADPSANIIFGAVV 96
Cdd:smart00865  81 ADPDAFIIWGPVI 93
PRK13018 PRK13018
cell division protein FtsZ; Provisional
 2-96 3.33e-30

cell division protein FtsZ; Provisional


Pssm-ID: 237273 [Multi-domain]  Cd Length: 378  Bit Score: 109.71  E-value: 3.33e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2545607029   2 PGLVNVDFADVKAVMKDSGTAMLGVGVSSSKNRAEEAAEQATLAPLIGSSIQSATGVVYNITGGKDITLQEVNRVSQVVT 81
Cdd:PRK13018  220 PSLINLDFADVKSVMKGGGVAMMGVGEAKGQNRAMEAVRAALANPLLDVDYRGAKGALVHITGGPDLTLKEANEAASRIT 299

                          90
                  ....*....|....*
gi 2545607029  82 SLADPSANIIFGAVV 96
Cdd:PRK13018  300 EELDPEANIIWGARI 314
ftsZ TIGR00065
cell division protein FtsZ; This family consists of cell division protein FtsZ, a GTPase found ...
 1-95 5.65e-27

cell division protein FtsZ; This family consists of cell division protein FtsZ, a GTPase found in bacteria, the chloroplast of plants, and in archaebacteria. Structurally similar to tubulin, FtsZ undergoes GTP-dependent polymerization into filaments that form a cytoskeleton involved in septum synthesis. [Cellular processes, Cell division]


Pssm-ID: 272884 [Multi-domain]  Cd Length: 349  Bit Score: 100.85  E-value: 5.65e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2545607029   1 IPGLVNVDFADVKAVMKDSGTAMLGVGVSSSK---NRAEEAAEQATLAPLIGS-SIQSATGVVYNITGGKDITLQEVNRV 76
Cdd:TIGR00065 208 KPGLINIDFADVRAVMSGGGVAMMGIGEALGEdtaNRAFEAVRKALSSPLLDVdKISGAKGALVHITGGADLTLLEAEEI 287

                          90
                  ....*....|....*....
gi 2545607029  77 SQVVTSLADPSANIIFGAV 95
Cdd:TIGR00065 288 QEIITSELDQDANIIWGAI 306
FtsZ_C pfam12327
FtsZ family, C-terminal domain; This family includes the bacterial FtsZ family of proteins. ...
 20-96 5.22e-23

FtsZ family, C-terminal domain; This family includes the bacterial FtsZ family of proteins. Members of this family are involved in polymer formation. FtsZ is the polymer-forming protein of bacterial cell division. It is part of a ring in the middle of the dividing cell that is required for constriction of cell membrane and cell envelope to yield two daughter cells. FtsZ is a GTPase, like tubulin. FtsZ can polymerize into tubes, sheets, and rings in vitro and is ubiquitous in eubacteria and archaea.


Pssm-ID: 463534 [Multi-domain]  Cd Length: 95  Bit Score: 84.56  E-value: 5.22e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2545607029 20 GTAMLGVGVSSSKNRAEEAAEQATLAPLIGSSIQSATGVVYNITGGKDITLQEVNRVSQVVTSLADPSANIIFGAVV 96
Cdd:pfam12327  1 GVAMMGTGEASGENRAEEAAEAAISSPLLDVDLSGARGVLVNITGGPDLTLFEANEAAETIREEVDPDANIIFGTVI 77
 
Name Accession Description Interval E-value
FtsZ COG0206
Cell division GTPase FtsZ [Cell cycle control, cell division, chromosome partitioning];
1-96 7.39e-40

Cell division GTPase FtsZ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 439976 [Multi-domain]  Cd Length: 347  Bit Score: 134.47  E-value: 7.39e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2545607029   1 IPGLVNVDFADVKAVMKDSGTAMLGVGVSSSKNRAEEAAEQATLAPLI-GSSIQSATGVVYNITGGKDITLQEVNRVSQV 79
Cdd:COG0206   203 KPGLINLDFADVKTVMSNGGVALMGIGEASGENRAEEAAEKAISSPLLeDVSISGAKGVLVNITGGSDLTLDEVNEAAEI 282

                          90
                  ....*....|....*..
gi 2545607029  80 VTSLADPSANIIFGAVV 96
Cdd:COG0206   283 IQEEADPDANIIFGAVI 299
FtsZ_type1 cd02201
Filamenting temperature sensitive mutant Z, type 1; FtsZ is a GTPase that is similar to the ...
 1-96 1.90e-39

Filamenting temperature sensitive mutant Z, type 1; FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes. FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at the site of bacterial cell division, which is required for constriction of cell membrane and cell envelope to yield two daughter cells.


Pssm-ID: 276961 [Multi-domain]  Cd Length: 303  Bit Score: 132.14  E-value: 1.90e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2545607029   1 IPGLVNVDFADVKAVMKDSGTAMLGVGVSSSKNRAEEAAEQATLAPLIGSSIQSATGVVYNITGGKDITLQEVNRVSQVV 80
Cdd:cd02201   192 KPGLINLDFADVKTVMKNGGLALMGIGEASGENRAEEAVEKALNSPLLEDDIKGAKGVLVNITGGPDLTLEEVNEAAEII 271

                          90
                  ....*....|....*.
gi 2545607029  81 TSLADPSANIIFGAVV 96
Cdd:cd02201   272 TEKADPDANIIFGAVI 287
Tubulin_C smart00865
Tubulin/FtsZ family, C-terminal domain; This domain is found in the tubulin alpha, beta and ...
 5-96 1.12e-30

Tubulin/FtsZ family, C-terminal domain; This domain is found in the tubulin alpha, beta and gamma chains, as well as the bacterial FtsZ family of proteins. These proteins are GTPases and are involved in polymer formation. Tubulin is the major component of microtubules, while FtsZ is the polymer-forming protein of bacterial cell division, it is part of a ring in the middle of the dividing cell that is required for constriction of cell membrane and cell envelope to yield two daughter cells. FtsZ can polymerise into tubes, sheets, and rings in vitro and is ubiquitous in bacteria and archaea. This is the C-terminal domain.


Pssm-ID: 214868 [Multi-domain]  Cd Length: 120  Bit Score: 104.55  E-value: 1.12e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2545607029    5 VNVDFADVKAVMKDSGTAMLGVGVSSSKNRAEEAAEQATLAPLI-GSSIQSATGVVYNITGGKDITLQEVNRVSQVVTSL 83
Cdd:smart00865   1 INVDFADVKTVMVPMGFAMMGIGPASGENRALEAAELAISSPLLeDSNIMGAKGVLVNITGGPDLTLKEVNEAMERIREK 80

                           90
                   ....*....|...
gi 2545607029   84 ADPSANIIFGAVV 96
Cdd:smart00865  81 ADPDAFIIWGPVI 93
PRK13018 PRK13018
cell division protein FtsZ; Provisional
 2-96 3.33e-30

cell division protein FtsZ; Provisional


Pssm-ID: 237273 [Multi-domain]  Cd Length: 378  Bit Score: 109.71  E-value: 3.33e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2545607029   2 PGLVNVDFADVKAVMKDSGTAMLGVGVSSSKNRAEEAAEQATLAPLIGSSIQSATGVVYNITGGKDITLQEVNRVSQVVT 81
Cdd:PRK13018  220 PSLINLDFADVKSVMKGGGVAMMGVGEAKGQNRAMEAVRAALANPLLDVDYRGAKGALVHITGGPDLTLKEANEAASRIT 299

                          90
                  ....*....|....*
gi 2545607029  82 SLADPSANIIFGAVV 96
Cdd:PRK13018  300 EELDPEANIIWGARI 314
ftsZ TIGR00065
cell division protein FtsZ; This family consists of cell division protein FtsZ, a GTPase found ...
 1-95 5.65e-27

cell division protein FtsZ; This family consists of cell division protein FtsZ, a GTPase found in bacteria, the chloroplast of plants, and in archaebacteria. Structurally similar to tubulin, FtsZ undergoes GTP-dependent polymerization into filaments that form a cytoskeleton involved in septum synthesis. [Cellular processes, Cell division]


Pssm-ID: 272884 [Multi-domain]  Cd Length: 349  Bit Score: 100.85  E-value: 5.65e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2545607029   1 IPGLVNVDFADVKAVMKDSGTAMLGVGVSSSK---NRAEEAAEQATLAPLIGS-SIQSATGVVYNITGGKDITLQEVNRV 76
Cdd:TIGR00065 208 KPGLINIDFADVRAVMSGGGVAMMGIGEALGEdtaNRAFEAVRKALSSPLLDVdKISGAKGALVHITGGADLTLLEAEEI 287

                          90
                  ....*....|....*....
gi 2545607029  77 SQVVTSLADPSANIIFGAV 95
Cdd:TIGR00065 288 QEIITSELDQDANIIWGAI 306
FtsZ_C pfam12327
FtsZ family, C-terminal domain; This family includes the bacterial FtsZ family of proteins. ...
 20-96 5.22e-23

FtsZ family, C-terminal domain; This family includes the bacterial FtsZ family of proteins. Members of this family are involved in polymer formation. FtsZ is the polymer-forming protein of bacterial cell division. It is part of a ring in the middle of the dividing cell that is required for constriction of cell membrane and cell envelope to yield two daughter cells. FtsZ is a GTPase, like tubulin. FtsZ can polymerize into tubes, sheets, and rings in vitro and is ubiquitous in eubacteria and archaea.


Pssm-ID: 463534 [Multi-domain]  Cd Length: 95  Bit Score: 84.56  E-value: 5.22e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2545607029 20 GTAMLGVGVSSSKNRAEEAAEQATLAPLIGSSIQSATGVVYNITGGKDITLQEVNRVSQVVTSLADPSANIIFGAVV 96
Cdd:pfam12327  1 GVAMMGTGEASGENRAEEAAEAAISSPLLDVDLSGARGVLVNITGGPDLTLFEANEAAETIREEVDPDANIIFGTVI 77
FtsZ_CetZ-like cd02191
Subfamily of FitZ and Cell-structure-related euryarchaeota tubulin/FtsZ homolog-like; FtsZ is ...
 2-96 1.89e-15

Subfamily of FitZ and Cell-structure-related euryarchaeota tubulin/FtsZ homolog-like; FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes. CetZ-like proteins are related to tubulin and FtsZ and co-exists with FtsZ in many archaea. However, a recent study found that Cetz proteins (formerly annotated FtsZ type 2) are not required for cell division. Instead, CetZ proteins are shown to be involved in controlling archaeal cell shape dynamics. The results from inactivation studies of CetZ proteins in Haloferax volcanii suggest that CetZ1 is essential for normal swimming motility and rod-cell development.


Pssm-ID: 276960 [Multi-domain]  Cd Length: 308  Bit Score: 69.13  E-value: 1.89e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2545607029   2 PGLVNVDFADVKAVMKDSGTAMLGVGVSSSK-NRAEEAAEQATLAPLIGSSIQSATGVVYNITGGKD-ITLQEVNRVSQV 79
Cdd:cd02191   199 TGLSVVDFADVKTVMNSGGMAMLGYGSADASiNRAREATRRALRTPLLLPDASGADGALVVIAGEPDtLPLKEVERVRRW 278

                          90
                  ....*....|....*..
gi 2545607029  80 VTSLADpSANIIFGAVV 96
Cdd:cd02191   279 VEDETG-SATVRGGDVI 294
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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