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Conserved domains on  [gi|2553043684|gb|WKW55265|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Vidua chalybeata]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-250 4.90e-112

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 325.62  E-value: 4.90e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM 80
Cdd:MTH00112   55 AATKYFLTQAAASALILFSSTTNAWNTGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQ 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  81 KLPPIALLFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTA 160
Cdd:MTH00112  135 KLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTP 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 161 VFLALNSMKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYL 240
Cdd:MTH00112  215 MFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYL 294

                         250
                  ....*....|
gi 2553043684 241 RLAYCTAITL 250
Cdd:MTH00112  295 RLTYISTITL 304
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-250 4.90e-112

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 325.62  E-value: 4.90e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM 80
Cdd:MTH00112   55 AATKYFLTQAAASALILFSSTTNAWNTGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQ 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  81 KLPPIALLFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTA 160
Cdd:MTH00112  135 KLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTP 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 161 VFLALNSMKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYL 240
Cdd:MTH00112  215 MFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYL 294

                         250
                  ....*....|
gi 2553043684 241 RLAYCTAITL 250
Cdd:MTH00112  295 RLTYISTITL 304
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 1-243 4.81e-14

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 70.75  E-value: 4.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHPVSSLVLT------------SAIAMKLGLVPFHFWFPEVMQGS 68
Cdd:TIGR01770 154 AGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGA 233

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  69 SLLTGLLLSTLMKLPPIAL---LFMTAQS----LNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGW--MAII 139
Cdd:TIGR01770 234 PTPVTAFFSIVPKIAIFAVflrLFLYILFgfseAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYilIGLL 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 140 ITYYPKLTLLNFYL--YAVMTTAVFLALNSMK------ALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWL 211
Cdd:TIGR01770 314 AGTLEGIKAVLFYIfiYALMSLGAFGVLSLLRsykdewIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFY 393

                         250       260       270
                  ....*....|....*....|....*....|..
gi 2553043684 212 IIQELTKQDMAPAATIISLLSLLSLFFYLRLA 243
Cdd:TIGR01770 394 VFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-214 1.07e-13

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 68.88  E-value: 1.07e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQL-----------THPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSS 69
Cdd:pfam00361  34 AGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssGLLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAP 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  70 LLTGLLLSTLM-KLPPIAL-----LFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIII--- 140
Cdd:pfam00361 114 TPVSALLAATLvKAGGYGLirrslLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALgag 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 141 -TYYPKLTLLNFYLYAVMTTAVFLALNS-----MKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQ 214
Cdd:pfam00361 194 tIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 1-244 2.73e-12

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 65.91  E-value: 2.73e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLF-SSMTNAWhTGQWDITQLTHPVSSLVLTS------------AIAMKLGLVPFHFWFPEVMQG 67
Cdd:COG1007   154 AALKYFLLGALSSGFLLYgISLLYGA-TGSLNLAGIAAALAAGGANSpllllglvlvlaGLAFKLSAVPFHMWTPDVYEG 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  68 SSLLTGLLLSTLMKLPPIALL-------FMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIII 140
Cdd:COG1007   233 APTPVTAFLATAPKIAAFAALlrllveaFPGLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGL 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 141 TYYPKLTL--LNFYL--YAVMTTAVFLALNSMK-----ALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWL 211
Cdd:COG1007   313 AAGTPLGVsaALFYLlaYLFMNLGAFAVILLLSrkggeAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFY 392

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2553043684 212 IIQELTKQDMAPAATIISLLSLLSLFFYLRLAY 244
Cdd:COG1007   393 VFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-250 4.90e-112

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 325.62  E-value: 4.90e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM 80
Cdd:MTH00112   55 AATKYFLTQAAASALILFSSTTNAWNTGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQ 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  81 KLPPIALLFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTA 160
Cdd:MTH00112  135 KLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTP 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 161 VFLALNSMKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYL 240
Cdd:MTH00112  215 MFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYL 294

                         250
                  ....*....|
gi 2553043684 241 RLAYCTAITL 250
Cdd:MTH00112  295 RLTYISTITL 304
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-250 2.20e-90

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 270.52  E-value: 2.20e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM 80
Cdd:MTH00135   55 ATTKYFLTQATAAAMILFASTTNAWLTGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQ 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  81 KLPPIALLFMTAQSlNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTA 160
Cdd:MTH00135  135 KLAPFALILQIAPT-NPTLLITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSS 213

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 161 VFLALNSMKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYL 240
Cdd:MTH00135  214 AFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYL 293

                         250
                  ....*....|
gi 2553043684 241 RLAYCTAITL 250
Cdd:MTH00135  294 RLSYAMTLTI 303
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-250 3.42e-88

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 264.86  E-value: 3.42e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM 80
Cdd:MTH00070   55 AATKYFLTQASASALILFSSTINAWFTGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQ 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  81 KLPPIALLFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTA 160
Cdd:MTH00070  135 KLAPMALLIQISHLLNSNLLIIMGLLSTLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSS 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 161 VFLALNSMKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYL 240
Cdd:MTH00070  215 MFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYL 294

                         250
                  ....*....|
gi 2553043684 241 RLAYCTAITL 250
Cdd:MTH00070  295 RLSYAMSLTT 304
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-250 3.71e-80

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 244.37  E-value: 3.71e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM 80
Cdd:MTH00105   55 AATKYFLTQATASMLLMMAIIINLMYSGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQ 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  81 KLPPIALLFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTA 160
Cdd:MTH00105  135 KLAPLSILYQISPSINPNLLLTLAILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLT 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 161 VFLALNSMKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYL 240
Cdd:MTH00105  215 MFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYM 294

                         250
                  ....*....|
gi 2553043684 241 RLAYCTAITL 250
Cdd:MTH00105  295 RLIYSTSLTM 304
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-250 1.36e-62

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 199.42  E-value: 1.36e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM 80
Cdd:MTH00200   55 ATTKYFIIQATASALLLFGGLLNAWTSGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQ 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  81 KLPPIALLFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTA 160
Cdd:MTH00200  135 KLAPFALLIQLAPALNSNILLLLGLLSVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLT 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 161 VFLALNSMKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYL 240
Cdd:MTH00200  215 VFLLLNLLNSTKINSLSSSKTKNPILSMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYL 294

                         250
                  ....*....|
gi 2553043684 241 RLAYCTAITL 250
Cdd:MTH00200  295 RLSYLTLLTL 304
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-250 1.11e-56

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 184.36  E-value: 1.11e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM 80
Cdd:MTH00041   55 ATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQ 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  81 KLPPIALLFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTA 160
Cdd:MTH00041  135 KIAPLILLISISNLLNSNILILCGILSVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTS 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 161 VFLALNSMKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYL 240
Cdd:MTH00041  215 IFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYL 294

                         250
                  ....*....|
gi 2553043684 241 RLAYCTAITL 250
Cdd:MTH00041  295 RISFNTSLTL 304
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-244 7.99e-36

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 129.56  E-value: 7.99e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWhtgqwdITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM 80
Cdd:MTH00160   56 SSLKYFLIQALASIILLFSIILNML------NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQ 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  81 KLPPIALLFMTaqsLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTA 160
Cdd:MTH00160  130 KIAPLILLSYL---INNNFIIIIIILSAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLS 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 161 VFLALNSMKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYL 240
Cdd:MTH00160  207 IILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYL 286


                  ....
gi 2553043684 241 RLAY 244
Cdd:MTH00160  287 RISY 290
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-242 3.15e-33

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 122.97  E-value: 3.15e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSmtnawhTGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM 80
Cdd:MTH00011   57 AAVKYFLAQALGSGLLLLGM------TMMWSFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQ 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  81 KLPPIALLFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTA 160
Cdd:MTH00011  131 KIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTP 210

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 161 VFLALNSMKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYL 240
Cdd:MTH00011  211 LMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYL 290


                  ..
gi 2553043684 241 RL 242
Cdd:MTH00011  291 NL 292
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-244 2.90e-30

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 114.98  E-value: 2.90e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDitqlthpvSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM 80
Cdd:MTH00144   55 SVVKYFIIQSLGSSLLIFGSLIMYNLSFSWF--------SMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQ 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  81 KLPPIALLFMTAQSLN-SSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTT 159
Cdd:MTH00144  127 KVAPLFLLSNFLDLYWlAYLLCVISVLSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSG 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 160 AVFLALNSMKALSLpTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFY 239
Cdd:MTH00144  207 FLFFSLWSGDSGSM-KDLGSLKPSYKTGLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFY 285


                  ....*
gi 2553043684 240 LRLAY 244
Cdd:MTH00144  286 LSVFF 290
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 1-248 7.64e-27

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 105.52  E-value: 7.64e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTgqwditqLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM 80
Cdd:MTH00197   49 GAMKYFLFQEFGSALLLMGGSLSFSNL-------YLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQ 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  81 KLPPIALLfmTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTA 160
Cdd:MTH00197  122 KLAPLLIL--AFNSSSFMGLLICSVLSSLIGGIGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFM 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 161 VFLALNSMKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYL 240
Cdd:MTH00197  200 LFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYL 279


                  ....*...
gi 2553043684 241 RLAYCTAI 248
Cdd:MTH00197  280 SLAYKSLI 287
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 1-243 4.81e-14

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 70.75  E-value: 4.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHPVSSLVLT------------SAIAMKLGLVPFHFWFPEVMQGS 68
Cdd:TIGR01770 154 AGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGA 233

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  69 SLLTGLLLSTLMKLPPIAL---LFMTAQS----LNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGW--MAII 139
Cdd:TIGR01770 234 PTPVTAFFSIVPKIAIFAVflrLFLYILFgfseAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYilIGLL 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 140 ITYYPKLTLLNFYL--YAVMTTAVFLALNSMK------ALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWL 211
Cdd:TIGR01770 314 AGTLEGIKAVLFYIfiYALMSLGAFGVLSLLRsykdewIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFY 393

                         250       260       270
                  ....*....|....*....|....*....|..
gi 2553043684 212 IIQELTKQDMAPAATIISLLSLLSLFFYLRLA 243
Cdd:TIGR01770 394 VFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-214 1.07e-13

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 68.88  E-value: 1.07e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQL-----------THPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSS 69
Cdd:pfam00361  34 AGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssGLLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAP 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  70 LLTGLLLSTLM-KLPPIAL-----LFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIII--- 140
Cdd:pfam00361 114 TPVSALLAATLvKAGGYGLirrslLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALgag 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 141 -TYYPKLTLLNFYLYAVMTTAVFLALNS-----MKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQ 214
Cdd:pfam00361 194 tIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 1-213 2.64e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 68.52  E-value: 2.64e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFS-------------SMTNAWHTGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQG 67
Cdd:MTH00196   45 AGLKYFVLGALSSGLFLFGcallcgttgglhlSYINLVLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEG 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  68 SSLLTGLLLSTLMKLPPIALLFMTaqSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYP--- 144
Cdd:MTH00196  125 APTKTTALLAIVPKLGIFSILVSI--GLNVNILLIGGLFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfes 202

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2553043684 145 -KLTLLNFYLYAVMTTAVF---LALNSMKALsLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLII 213
Cdd:MTH00196  203 iQASLVYLFIYIIMSICVFsiiLALNVYKNL-IIEFSGLSRRLPILAITLALTFLSIAGIPPLVGFLGKWLIL 274
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 1-244 2.73e-12

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 65.91  E-value: 2.73e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLF-SSMTNAWhTGQWDITQLTHPVSSLVLTS------------AIAMKLGLVPFHFWFPEVMQG 67
Cdd:COG1007   154 AALKYFLLGALSSGFLLYgISLLYGA-TGSLNLAGIAAALAAGGANSpllllglvlvlaGLAFKLSAVPFHMWTPDVYEG 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  68 SSLLTGLLLSTLMKLPPIALL-------FMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIII 140
Cdd:COG1007   233 APTPVTAFLATAPKIAAFAALlrllveaFPGLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGL 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 141 TYYPKLTL--LNFYL--YAVMTTAVFLALNSMK-----ALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWL 211
Cdd:COG1007   313 AAGTPLGVsaALFYLlaYLFMNLGAFAVILLLSrkggeAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFY 392

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2553043684 212 IIQELTKQDMAPAATIISLLSLLSLFFYLRLAY 244
Cdd:COG1007   393 VFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
1-242 3.10e-12

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 65.61  E-value: 3.10e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHPVSS------------LVLTSAIAMKLGLVPFHFWFPEVMQGS 68
Cdd:PRK05777  155 AAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKALADgsgnsllllfglVFLLVGLAFKLSAVPFHMWTPDVYEGA 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  69 SLLTGLLLSTLMKLPPIALL-------FMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWM--AII 139
Cdd:PRK05777  235 PTPVTAFLATAPKIAAFAVLlrllvvaFGGLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlvGLA 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 140 ITYYPKLTLLNFYL--YAVMTTAVFLALNSMK-----ALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLI 212
Cdd:PRK05777  315 AGTAEGYSAVLFYLlaYLFMTLGAFGVISLLRrkggeAESISDFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYV 394

                         250       260       270
                  ....*....|....*....|....*....|
gi 2553043684 213 IQELTKQDMAPAATIISLLSLLSLFFYLRL 242
Cdd:PRK05777  395 FEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 1-213 6.89e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 64.65  E-value: 6.89e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDI----TQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLL 76
Cdd:MTH00199  149 AGLKYFVLGAVSSGLFLFGCALLYGLTGETSIqginSILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALL 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  77 STLMKLPPIALLFMTAQSLNssLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGW----MAIIITYYPKLTLLNFY 152
Cdd:MTH00199  229 ATVPKIGVFSILVQIGPVTN--VVLICAVLSIIYGAIGALNQTKIKRLLAYSGIGHMGFilfgVAIGSFESIQASLIYMI 306

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2553043684 153 LYAVMTTAVF---LALNSMKALsLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLII 213
Cdd:MTH00199  307 IYVIMSICSFsiiLSLKLTKGL-IVEVSGLSRKNPVIALTLALTFLSIAGIPPLAGFLSKWLIL 369
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 42-156 1.09e-09

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 58.33  E-value: 1.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  42 LVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLppIALLFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQV 121
Cdd:MTH00198  303 LFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--TVYILLTSLVITSKLLLSVAIISLVVGAFGALNQTRI 380

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2553043684 122 RKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAV 156
Cdd:MTH00198  381 KRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAV 415
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 1-228 3.40e-07

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 50.53  E-value: 3.40e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHPVSSL----------VLTSAIAMKLGLVPFHFWFPEVMQGSSL 70
Cdd:COG0651   158 AGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLAELdpglllaafaLLLVGFGIKAALFPLHFWLPDAYPAAPS 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  71 LTGLLLSTLM-KLPPIAL-----LFMTAQSLN--SSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITY 142
Cdd:COG0651   238 PVSALLSGLLtKVGVYAIlrvltLLFGADPALflGTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGL 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 143 YPKLTLLNFYLY----AVMTTAVFLA----LNSMKALSLPTLMTAWTKAPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQ 214
Cdd:COG0651   318 GTPLGLAGALFHllnhALAKALLFLAagaiERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQ 397

                         250
                  ....*....|....
gi 2553043684 215 ELTKQDMAPAATII 228
Cdd:COG0651   398 AALEAGAWLLAAVL 411
ndhB CHL00049
NADH dehydrogenase subunit 2
 1-154 3.55e-07

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 50.39  E-value: 3.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVL--FSSM--TNAWHTGQWDI------TQLTHPVSSLV----LTSAIAMKLGLVPFHFWFPEVMQ 66
Cdd:CHL00049  163 ATMKYLLMGGASSSILVygFSWLygLSGGEIELQEIvnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTPDVYE 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  67 GSSLLTGLLLSTLMKLPPIAL-------LFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAI- 138
Cdd:CHL00049  243 GSPTPVVAFLSVTSKVAASALatrifdiPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIg 322

                         170       180
                  ....*....|....*....|..
gi 2553043684 139 IIT------YYPKLTLLNFYLY 154
Cdd:CHL00049  323 IIVgdsndgYASMITYMLFYIF 344
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-140 1.65e-05

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 45.32  E-value: 1.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAW-HTGQWDITQL-THPVSSLVLT-------SAIAMKLGLVPFHFWFPEVM-QGSSL 70
Cdd:TIGR01972 157 AAMKFFLYTLAGSLLMLLAILGLYFlGGGTFDLLELlNLPLPFGVQTwlflaffIAFAVKVPLFPLHTWLPDAHvEAPTA 236

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2553043684  71 LTGLLLSTLMKLPPIAL------LFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIII 140
Cdd:TIGR01972 237 GSVILAGVLLKMGTYGFlrfnlpLFPDASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGI 312
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-138 1.68e-05

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 45.46  E-value: 1.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQW--DITQLTHPVSSLVLTSAI--------AMKLGLVPFHFWFPEV-MQGSS 69
Cdd:COG1008   162 AAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAAPLPLTAQLLLflaffiafAVKVPMFPFHTWLPDAhVEAPT 241

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2553043684  70 LLTGLLLSTLMKLPPIAL------LFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAI 138
Cdd:COG1008   242 AGSVLLAGVLLKMGGYGLlrfalpLFPEASAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLL 316
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
1-138 1.74e-05

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 45.43  E-value: 1.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLF-SSMTNAWHTGQwdiTQLTHPVSSLV-------------LTSAIAMKLGLVPFHFWFPEVMQ 66
Cdd:PRK02504  162 AALKYLLIGAASSAIFLYgSSLLYGLSGGS---TQLSAIALALItspslglalalvfVIAGIAFKISAVPFHQWTPDVYE 238

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2553043684  67 GSSLLTGLLLSTLMKLPPIAL---LFMTAQSLNSS----LLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAI 138
Cdd:PRK02504  239 GSPTPVVAFLSVGSKAAGFALairLLVTAFPSFDEqwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMI 317
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
1-136 2.72e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 41.61  E-value: 2.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTG--QWDITQL---THPVSS-LVLTSAI----AMKLGLVPFHFWFPEV-MQGSS 69
Cdd:PRK06473  158 AATKFLLYTAISGILILVSFLGLVWLSGasSFDYEPLrshTLPLSTqLLLLAPIlvgfGIKIPLVPFHTWLPDAhVEAST 237

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2553043684  70 LLTGLLLSTLMKLPPIALL------FMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWM 136
Cdd:PRK06473  238 PVSVLLAGVLLKLGTYGLLrfgvglFPEAWVYLAPWLATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYI 310
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-140 5.41e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 40.79  E-value: 5.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWHTGQ--WDITQLTHPVSSLVLT--------SAIAMKLGLVPFHFWFPEVM-QGSS 69
Cdd:PRK12561  138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGAKSYPLALElllyagflIAFGVKLPIFPLHTWLPDAHgEASA 217

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2553043684  70 LLTGLLLSTLMKLPPIALLFMTAQSLN------SSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIII 140
Cdd:PRK12561  218 PVSMILAGVLLKMGGYALIRFNVQMLPdahvyfAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLGI 294
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
38-214 1.52e-03

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 39.55  E-value: 1.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  38 PVSSLVLTSAIAMKLGLVPFhFWFPEVMQGSSLLTGLLLSTLMKLPPI-------ALLFMTAQSLNSSLLVLMAILSAAV 110
Cdd:PRK12663  207 TTIALLFLLAFGMKAALFPF-MWLPAAYHTPNTEVAALFAALLTKVGIyalirvfTLLFPQERELLHPLLATMAAITMVI 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 111 GGWMGLNQTQVRKILAFSSISHLGWM--AIIITYYPKLTLLNFYLYAVMT--TAVFLALNSMKAL----SLPTLMTAWTK 182
Cdd:PRK12663  286 GALGALAYKDIRRIAGYQVISSIGFIllGLALGTPAGINGAIFYLVHDMVvkTALFLIAGSLVRLtgyrSLQYLGGLYRK 365

                         170       180       190
                  ....*....|....*....|....*....|..
gi 2553043684 183 APSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQ 214
Cdd:PRK12663  366 EPLFGALFLILIFAIGGLPPFSGFWGKVLLVQ 397
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 26-140 1.75e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 39.52  E-value: 1.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  26 HTGQWDITQL-THPVSSLVLTSAIAM-------KLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSLNS 97
Cdd:PRK12644  183 AAGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLVARLAPGFAD 262

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2553043684  98 S-----LLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIII 140
Cdd:PRK12644  263 VpvwrpTVLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLV 310
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-212 1.86e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 39.31  E-value: 1.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFS---------SMTNAWHTGQWDITQLTHPVSSLVL-TSAIAMKLGLVPFHFWFPEVMQGSSL 70
Cdd:PRK08376  173 AGIKYMFVGSLASSMVLLGiallygqygTLNMAYLAVKMSENPTVVAKIALALfIAGLAMKSGAVPVHMWLPDAYPAAPS 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  71 LTGLLLSTLMKLPPIAL------LFMTAQSLNSS--LLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWM----AI 138
Cdd:PRK08376  253 SISAMLLVIKQAGLYALarvlfsIYGPAINLATVgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMllglGV 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684 139 IITYYpKLTLLNFYLYAVMTTAVFLALNS--MKAL---------------SLPTLMTAWTKAPSLSAMLLLTLLSLAGLP 201
Cdd:PRK08376  333 GLAAL-GDPAMASYGEIALAGGIYHIVNHalYKALlfltagaviyetgtrNLNELGGLARTMPKTTIAFLIGAAAIVGLP 411

                         250
                  ....*....|.
gi 2553043684 202 PLTGFLPKWLI 212
Cdd:PRK08376  412 PFNGFASKWLI 422
PRK12650 PRK12650
DUF4040 family protein;
26-140 3.21e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 38.49  E-value: 3.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684  26 HTGQW-DITQLTHPVSSLVLTSAIAmKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALL--FMTAQSLN---SSL 99
Cdd:PRK12650  196 HSDVWaEKPGLTTVVAVLIAVAAFT-KSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLlrFSPVFHDVavwNWL 274

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2553043684 100 LVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIII 140
Cdd:PRK12650  275 LIIVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIVATI 315
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 1-140 8.76e-03

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 37.10  E-value: 8.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2553043684   1 AATKYFLVQAAASALVLFSSMTNAWH----TGQWDITQL-THPVSSLVLTS-------AIAMKLGLVPFHFWFPEVM-QG 67
Cdd:PRK05846  162 AATKFFLYTLLGSLLMLVAIIYLVVVyynaTGTFDIADLlNLPLPPGVQYWlflaffiAFAVKMPMFPLHTWLPDAHvQA 241

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2553043684  68 SSLLTGLLLSTLMKLPPIALL------FMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIII 140
Cdd:PRK05846  242 PTAGSVLLAGILLKMGAYGLLrfslplFPDASHEFAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTLGI 320
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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