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Conserved domains on  [gi|446445141|ref|WP_000522996|]
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MULTISPECIES: organomercurial transporter MerC [Bacteria]

Protein Classification

MerC domain-containing protein( domain architecture ID 10014403)

MerC domain-containing protein similar to Acidithiobacillus ferrooxidans mercuric resistance protein MerC, an inner membrane protein that mediates mercury transport into the cytoplasm

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK13755 PRK13755
organomercurial transporter MerC;
1-140 2.38e-83

organomercurial transporter MerC;


:

Pssm-ID: 237490  Cd Length: 139  Bit Score: 240.74  E-value: 2.38e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446445141   1 MGLITRIAGKTGALGSVVSAMGCAACFPAIASFGAAIGLGFLSQYEGLFIGILLPMFAGIALLANAIAWLNHRQWRRTAL 80
Cdd:PRK13755   1 MGLITRIADKTGALGSVVSAMGCAACFPALASLGAAIGLGFLSQYEGLFISTLLPLFAAIALLANALGWFSHRQWLRSAL 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446445141  81 GTIGPILVLAAVFLMRAYGWqSGGLLYVGLALMVGVSVWDFISPAHRRCGPDSCELPEQR 140
Cdd:PRK13755  81 GMIGPALVLAAVFLLLGNGW-SANLLYVGLALMVGVSIWDFVSPAHRRCGPDSCELPAKR 139
 
Name Accession Description Interval E-value
PRK13755 PRK13755
organomercurial transporter MerC;
1-140 2.38e-83

organomercurial transporter MerC;


Pssm-ID: 237490  Cd Length: 139  Bit Score: 240.74  E-value: 2.38e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446445141   1 MGLITRIAGKTGALGSVVSAMGCAACFPAIASFGAAIGLGFLSQYEGLFIGILLPMFAGIALLANAIAWLNHRQWRRTAL 80
Cdd:PRK13755   1 MGLITRIADKTGALGSVVSAMGCAACFPALASLGAAIGLGFLSQYEGLFISTLLPLFAAIALLANALGWFSHRQWLRSAL 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446445141  81 GTIGPILVLAAVFLMRAYGWqSGGLLYVGLALMVGVSVWDFISPAHRRCGPDSCELPEQR 140
Cdd:PRK13755  81 GMIGPALVLAAVFLLLGNGW-SANLLYVGLALMVGVSIWDFVSPAHRRCGPDSCELPAKR 139
MerC pfam03203
MerC mercury resistance protein;
11-120 1.51e-14

MerC mercury resistance protein;


Pssm-ID: 427195  Cd Length: 105  Bit Score: 64.96  E-value: 1.51e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446445141   11 TGALGSVVSAMGCAAcFPAIASFGAAIGLGFLSqyEGLFIGILLPMFAGIALLANAIAWLNHRQWRRTALGTIGPILVLA 90
Cdd:pfam03203   1 LGILLSLLCAIHCLA-LPLLLALLPALGLGFLE--EPLFHRLLLALFALIALLALGLGYRRHRRWLPLVLGLLGLALLFL 77

                          90       100       110
                  ....*....|....*....|....*....|
gi 446445141   91 AVFLMraYGWQSGGLLYVGLALMVGVSVWD 120
Cdd:pfam03203  78 ALFLG--GEAIEVVLTYIGSALLAAAHVLN 105
 
Name Accession Description Interval E-value
PRK13755 PRK13755
organomercurial transporter MerC;
1-140 2.38e-83

organomercurial transporter MerC;


Pssm-ID: 237490  Cd Length: 139  Bit Score: 240.74  E-value: 2.38e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446445141   1 MGLITRIAGKTGALGSVVSAMGCAACFPAIASFGAAIGLGFLSQYEGLFIGILLPMFAGIALLANAIAWLNHRQWRRTAL 80
Cdd:PRK13755   1 MGLITRIADKTGALGSVVSAMGCAACFPALASLGAAIGLGFLSQYEGLFISTLLPLFAAIALLANALGWFSHRQWLRSAL 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446445141  81 GTIGPILVLAAVFLMRAYGWqSGGLLYVGLALMVGVSVWDFISPAHRRCGPDSCELPEQR 140
Cdd:PRK13755  81 GMIGPALVLAAVFLLLGNGW-SANLLYVGLALMVGVSIWDFVSPAHRRCGPDSCELPAKR 139
MerC pfam03203
MerC mercury resistance protein;
11-120 1.51e-14

MerC mercury resistance protein;


Pssm-ID: 427195  Cd Length: 105  Bit Score: 64.96  E-value: 1.51e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446445141   11 TGALGSVVSAMGCAAcFPAIASFGAAIGLGFLSqyEGLFIGILLPMFAGIALLANAIAWLNHRQWRRTALGTIGPILVLA 90
Cdd:pfam03203   1 LGILLSLLCAIHCLA-LPLLLALLPALGLGFLE--EPLFHRLLLALFALIALLALGLGYRRHRRWLPLVLGLLGLALLFL 77

                          90       100       110
                  ....*....|....*....|....*....|
gi 446445141   91 AVFLMraYGWQSGGLLYVGLALMVGVSVWD 120
Cdd:pfam03203  78 ALFLG--GEAIEVVLTYIGSALLAAAHVLN 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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