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Conserved domains on  [gi|447190449|ref|WP_001267705|]
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MULTISPECIES: mechanosensitive channel protein [Salmonella]

Protein Classification

mechanosensitive ion channel family protein( domain architecture ID 11485356)

mechanosensitive ion channel family protein functions in osmotic regulation in response to changing environmental and developmental signals; similar to Escherichia coli moderate conductance mechanosensitive channel YbiO

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK11465 PRK11465
putative mechanosensitive channel protein; Provisional
 1-740 0e+00

putative mechanosensitive channel protein; Provisional


:

Pssm-ID: 183147 [Multi-domain]  Cd Length: 741  Bit Score: 1361.00  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449   1 MRWTLFILFCLLGAPAHAVAIPGVTTGTST--SQQAAPEPSPEQKKAAYAALADVLENEASRNELIAQLREASTTPPTEP 78
Cdd:PRK11465   1 MRWILFILFCLLGAPAHAVSIPGVTTTTSTdsTTEPAPEPDIEQKKAAYAALADVLDNDTSRKELIDQLRTAAATPPAEP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449  79 APALAPPAAKDEKTVLENVTTVTRQYGDAFATRFAQLYRNITDAPHKPFNSQTFTNALTHFLFLAVAVFGFYSVIRLCAL 158
Cdd:PRK11465  81 VPKIVPPTLVEEKTVLQNVTEVSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFLMLAVLVFGFYWLIRLCAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 159 PLYRKMGLWARKKNRERSNWLQLPAMIVGAFIIDLLLLALTLFIGQMLSDNFHAGSRTIAFQQSLFLNAFALIEFFKAIL 238
Cdd:PRK11465 161 PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQLLSDNLNAGSRTIAFQQSLFLNAFALIEFFKAIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 239 RLIFCPNVPELRPFAIQDATARYWNRRMSSLSSLIGYGLIVAVPIISNQVNVQVGAMANVAIMLCITIWALYLIFKNKAE 318
Cdd:PRK11465 241 RLIFCPNVPELRPFTIQDASARYWNRRLSWLSSLIGYGLIVAVPIISNQVNVQVGALANVIIMLCMTVWALYLIFRNKKE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 319 ITQHLLSLAERSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFISGMFTRWIAK 398
Cdd:PRK11465 321 ITQHLLNLAERSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFTRWIAK 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 399 TITLSPHTQRNYPELQKRLNGWLSSALKVARFLTVCVAVMLLLNAWGLFDFWHWLHYGAGEKMVDILIRIALILFFSAVG 478
Cdd:PRK11465 401 TITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLNAWGLFDFWNWLQNGAGEKTVDILIRIALILFFSAVG 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 479 WTILASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVK 558
Cdd:PRK11465 481 WTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVK 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 559 DIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDAD 638
Cdd:PRK11465 561 DIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDAD 640

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 639 KANQALKDAVTALMETEDIRGLIIGEPTFAGIVSLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLANVRAPVQTY 718
Cdd:PRK11465 641 KANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTY 720

                        730       740
                 ....*....|....*....|..
gi 447190449 719 QVLPAPvGGPSPDSLPPREPTI 740
Cdd:PRK11465 721 QVLPAP-GATPAEPLPPGEPTL 741
 
Name Accession Description Interval E-value
PRK11465 PRK11465
putative mechanosensitive channel protein; Provisional
 1-740 0e+00

putative mechanosensitive channel protein; Provisional


Pssm-ID: 183147 [Multi-domain]  Cd Length: 741  Bit Score: 1361.00  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449   1 MRWTLFILFCLLGAPAHAVAIPGVTTGTST--SQQAAPEPSPEQKKAAYAALADVLENEASRNELIAQLREASTTPPTEP 78
Cdd:PRK11465   1 MRWILFILFCLLGAPAHAVSIPGVTTTTSTdsTTEPAPEPDIEQKKAAYAALADVLDNDTSRKELIDQLRTAAATPPAEP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449  79 APALAPPAAKDEKTVLENVTTVTRQYGDAFATRFAQLYRNITDAPHKPFNSQTFTNALTHFLFLAVAVFGFYSVIRLCAL 158
Cdd:PRK11465  81 VPKIVPPTLVEEKTVLQNVTEVSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFLMLAVLVFGFYWLIRLCAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 159 PLYRKMGLWARKKNRERSNWLQLPAMIVGAFIIDLLLLALTLFIGQMLSDNFHAGSRTIAFQQSLFLNAFALIEFFKAIL 238
Cdd:PRK11465 161 PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQLLSDNLNAGSRTIAFQQSLFLNAFALIEFFKAIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 239 RLIFCPNVPELRPFAIQDATARYWNRRMSSLSSLIGYGLIVAVPIISNQVNVQVGAMANVAIMLCITIWALYLIFKNKAE 318
Cdd:PRK11465 241 RLIFCPNVPELRPFTIQDASARYWNRRLSWLSSLIGYGLIVAVPIISNQVNVQVGALANVIIMLCMTVWALYLIFRNKKE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 319 ITQHLLSLAERSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFISGMFTRWIAK 398
Cdd:PRK11465 321 ITQHLLNLAERSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFTRWIAK 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 399 TITLSPHTQRNYPELQKRLNGWLSSALKVARFLTVCVAVMLLLNAWGLFDFWHWLHYGAGEKMVDILIRIALILFFSAVG 478
Cdd:PRK11465 401 TITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLNAWGLFDFWNWLQNGAGEKTVDILIRIALILFFSAVG 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 479 WTILASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVK 558
Cdd:PRK11465 481 WTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVK 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 559 DIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDAD 638
Cdd:PRK11465 561 DIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDAD 640

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 639 KANQALKDAVTALMETEDIRGLIIGEPTFAGIVSLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLANVRAPVQTY 718
Cdd:PRK11465 641 KANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTY 720

                        730       740
                 ....*....|....*....|..
gi 447190449 719 QVLPAPvGGPSPDSLPPREPTI 740
Cdd:PRK11465 721 QVLPAP-GATPAEPLPPGEPTL 741
MscS COG0668
Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];
438-720 6.20e-43

Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440432 [Multi-domain]  Cd Length: 276  Bit Score: 156.58  E-value: 6.20e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 438 MLLLNAWGLFDFWHWLHYGAGEkMVDILIRIALILFFSAVGWTILASLIENRLASdihgrplpSARTRTLLTLFRNALAV 517
Cdd:COG0668    1 EALAQLWSLLGLLLLLGELLLA-LLPKLLLALLILLIGWLLIRLLRRLIRRLLRR--------ARRDRTLLPLLRNILKI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 518 IISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGV 597
Cdd:COG0668   72 LIVIIAILLILSILGVNITSLLAGLGAAGLAIGLAAQDLLSNFIAGIFILLERPFRVGDWIEVGGVEGTVEEIGLRSTRL 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 598 RQDTGAYHIIPWSSI--TTFANFVRGIGS-VVANYDVDRHEDADKANQALKDAVTALmetedirGLIIGEPTFAGIVSLT 674
Cdd:COG0668  152 RTLDGRLVTIPNSKIlsSPITNYSRGPTRrVDVTIGVDYDTDIDKARELLKEILEEL-------PRILKDPAVVGVTELG 224

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 447190449 675 NTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLANVRAPVQTYQV 720
Cdd:COG0668  225 DSSVNLRVRAWTKPGDYWDVRRDIRERIKAALDEAGIEIPFPTRTV 270
MS_channel pfam00924
Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss: ...
 512-712 1.55e-40

Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss:Q58543 of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.


Pssm-ID: 459999 [Multi-domain]  Cd Length: 203  Bit Score: 147.36  E-value: 1.55e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449  512 RNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMS 591
Cdd:pfam00924   1 KKILKYLIIVVGILIVLSYLGVNVSALLAGLGALGLALGFALQDLVSNLVSGIIILFEKPFKIGDWIEIGDIEGTVEDIG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449  592 IRSVGVRQDTGAYHIIPWSSITT--FANFVR-GIGSVVANYDVDRHEDADKANQALKDAVTALMETEDIRgLIIGEPTFA 668
Cdd:pfam00924  81 LRTTTIRTFDGRLVTIPNSSILTsnIINYSRsPTRRVELSIGVAYSSDPDKLEKVIEILKEAAYEHPLVL-KDPEPPVVF 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 447190449  669 GIVSLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLANVR 712
Cdd:pfam00924 160 GEFGDSSLNFELRVWVKTLPGEYFNVRSELNLRIKKALEENGIE 203
 
Name Accession Description Interval E-value
PRK11465 PRK11465
putative mechanosensitive channel protein; Provisional
 1-740 0e+00

putative mechanosensitive channel protein; Provisional


Pssm-ID: 183147 [Multi-domain]  Cd Length: 741  Bit Score: 1361.00  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449   1 MRWTLFILFCLLGAPAHAVAIPGVTTGTST--SQQAAPEPSPEQKKAAYAALADVLENEASRNELIAQLREASTTPPTEP 78
Cdd:PRK11465   1 MRWILFILFCLLGAPAHAVSIPGVTTTTSTdsTTEPAPEPDIEQKKAAYAALADVLDNDTSRKELIDQLRTAAATPPAEP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449  79 APALAPPAAKDEKTVLENVTTVTRQYGDAFATRFAQLYRNITDAPHKPFNSQTFTNALTHFLFLAVAVFGFYSVIRLCAL 158
Cdd:PRK11465  81 VPKIVPPTLVEEKTVLQNVTEVSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFLMLAVLVFGFYWLIRLCAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 159 PLYRKMGLWARKKNRERSNWLQLPAMIVGAFIIDLLLLALTLFIGQMLSDNFHAGSRTIAFQQSLFLNAFALIEFFKAIL 238
Cdd:PRK11465 161 PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQLLSDNLNAGSRTIAFQQSLFLNAFALIEFFKAIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 239 RLIFCPNVPELRPFAIQDATARYWNRRMSSLSSLIGYGLIVAVPIISNQVNVQVGAMANVAIMLCITIWALYLIFKNKAE 318
Cdd:PRK11465 241 RLIFCPNVPELRPFTIQDASARYWNRRLSWLSSLIGYGLIVAVPIISNQVNVQVGALANVIIMLCMTVWALYLIFRNKKE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 319 ITQHLLSLAERSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFISGMFTRWIAK 398
Cdd:PRK11465 321 ITQHLLNLAERSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFTRWIAK 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 399 TITLSPHTQRNYPELQKRLNGWLSSALKVARFLTVCVAVMLLLNAWGLFDFWHWLHYGAGEKMVDILIRIALILFFSAVG 478
Cdd:PRK11465 401 TITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLNAWGLFDFWNWLQNGAGEKTVDILIRIALILFFSAVG 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 479 WTILASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVK 558
Cdd:PRK11465 481 WTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVK 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 559 DIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDAD 638
Cdd:PRK11465 561 DIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDAD 640

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 639 KANQALKDAVTALMETEDIRGLIIGEPTFAGIVSLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLANVRAPVQTY 718
Cdd:PRK11465 641 KANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTY 720

                        730       740
                 ....*....|....*....|..
gi 447190449 719 QVLPAPvGGPSPDSLPPREPTI 740
Cdd:PRK11465 721 QVLPAP-GATPAEPLPPGEPTL 741
MscS COG0668
Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];
438-720 6.20e-43

Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440432 [Multi-domain]  Cd Length: 276  Bit Score: 156.58  E-value: 6.20e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 438 MLLLNAWGLFDFWHWLHYGAGEkMVDILIRIALILFFSAVGWTILASLIENRLASdihgrplpSARTRTLLTLFRNALAV 517
Cdd:COG0668    1 EALAQLWSLLGLLLLLGELLLA-LLPKLLLALLILLIGWLLIRLLRRLIRRLLRR--------ARRDRTLLPLLRNILKI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 518 IISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGV 597
Cdd:COG0668   72 LIVIIAILLILSILGVNITSLLAGLGAAGLAIGLAAQDLLSNFIAGIFILLERPFRVGDWIEVGGVEGTVEEIGLRSTRL 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 598 RQDTGAYHIIPWSSI--TTFANFVRGIGS-VVANYDVDRHEDADKANQALKDAVTALmetedirGLIIGEPTFAGIVSLT 674
Cdd:COG0668  152 RTLDGRLVTIPNSKIlsSPITNYSRGPTRrVDVTIGVDYDTDIDKARELLKEILEEL-------PRILKDPAVVGVTELG 224

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 447190449 675 NTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLANVRAPVQTYQV 720
Cdd:COG0668  225 DSSVNLRVRAWTKPGDYWDVRRDIRERIKAALDEAGIEIPFPTRTV 270
MS_channel pfam00924
Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss: ...
 512-712 1.55e-40

Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss:Q58543 of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.


Pssm-ID: 459999 [Multi-domain]  Cd Length: 203  Bit Score: 147.36  E-value: 1.55e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449  512 RNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMS 591
Cdd:pfam00924   1 KKILKYLIIVVGILIVLSYLGVNVSALLAGLGALGLALGFALQDLVSNLVSGIIILFEKPFKIGDWIEIGDIEGTVEDIG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449  592 IRSVGVRQDTGAYHIIPWSSITT--FANFVR-GIGSVVANYDVDRHEDADKANQALKDAVTALMETEDIRgLIIGEPTFA 668
Cdd:pfam00924  81 LRTTTIRTFDGRLVTIPNSSILTsnIINYSRsPTRRVELSIGVAYSSDPDKLEKVIEILKEAAYEHPLVL-KDPEPPVVF 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 447190449  669 GIVSLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLANVR 712
Cdd:pfam00924 160 GEFGDSSLNFELRVWVKTLPGEYFNVRSELNLRIKKALEENGIE 203
MscK COG3264
Small-conductance mechanosensitive channel MscK [Cell wall/membrane/envelope biogenesis];
465-720 1.30e-20

Small-conductance mechanosensitive channel MscK [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442495 [Multi-domain]  Cd Length: 281  Bit Score: 92.57  E-value: 1.30e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 465 LIRIALILFFSAVGWTILASLIENRLASDIHGRPlpsartrTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGA 544
Cdd:COG3264   23 LLLALLILVVTYLLARLLSRLLERRLLRRTRLDP-------GLRYLISKLIRYLIIVLGLLIALSALGIDLTALAALAGA 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 545 LGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITT--FANFVRG- 621
Cdd:COG3264   96 LGVGIGFGLQDIVSNFISGLILLFERPFRVGDWIEIGGTEGTVEEIGLRSTRIRTFDGEEVIIPNSELITnpVINWSLSd 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447190449 622 -IGSVVANYDVDRHEDADKANQALKDAVtalmetEDIRGLIIGEPTFAGIVSLTNTAFTLRVSFTTL-PLKQWTVRFALD 699
Cdd:COG3264  176 pRRRVEIPVGVAYGSDLEKVRELLLEAA------REHPRVLKDPAPSVLFTEFGDSSVNFELRFWVNdPRDRLRVRSDLN 249

                        250       260
                 ....*....|....*....|.
gi 447190449 700 SQVKKHFDLANVRAPVQTYQV 720
Cdd:COG3264  250 EAIKKAFREEGIEIPFPQRDV 270
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 551-593 5.03e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 40.42  E-value: 5.03e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 447190449  551 FGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIR 593
Cdd:PRK10929  915 FGLQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTR 957
PRK11281 PRK11281
mechanosensitive channel MscK;
551-594 7.04e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 39.89  E-value: 7.04e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 447190449  551 FGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRS 594
Cdd:PRK11281  918 FGLQEIFANFVSGLIILFERPVRIGDTVTIGTFSGTVSKIRIRA 961
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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