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Conserved domains on  [gi|487747180|ref|WP_001829321|]
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MULTISPECIES: TrkH family potassium uptake protein [Staphylococcus]

Protein Classification

TrkH family potassium uptake protein( domain architecture ID 11415019)

TrkH family potassium uptake protein is the membrane component of a potassium transport system and may bind other membrane components as well as periplasmic proteins; similar to Bacillus subtilis Ktr system potassium uptake protein D

Gene Ontology:  GO:0015079|GO:0030001|GO:0008324
PubMed:  20333436|10423425

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TrkG COG0168
Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];
13-447 5.16e-74

Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];


:

Pssm-ID: 439938 [Multi-domain]  Cd Length: 414  Bit Score: 238.06  E-value: 5.16e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  13 PQQGIILYYLFAIVVAFLLLNLPYVHKqGVEVNPIDTLFVAVSGISVTGLSPITIVDTYSTFGQIIILIILNIGGIGVMA 92
Cdd:COG0168    1 PAREGFLIVALVWLVGALLLALPFALS-GGGLSFLDALFEAVSGVTTTGLTVVDTLDTLPKFGLLWRSLLQWLGGLGIIV 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  93 IGTMLWVVLGkhigIRERQLIMLD-NNRDTMSGTVKLILEIVRTIFIIEFIGALLLAFYfyrdnpdlKNALMQGIFVSVS 171
Cdd:COG0168   80 LAVAILPLLG----IGGRQLFQAElPNEKLLPRIVRTAKALWLIYLGLTLIGALLLWLA--------GMALFDAIFHAFS 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180 172 ATTNGGLDITGESLVPYAkDYFVQTIVMFLIVLGSIGFPVLLELKAYIKNRvtnfRFSLFTKITTTTYLFLFLFGVIVVL 251
Cdd:COG0168  148 AFSTGGFSTHDDSLGAFN-SPAIELVIIVFMILGGLGFPVHYDLLRYRRFR----RLFSDTELRLYLTLILLVVGLLALF 222
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180 252 ILEHSNafkGLSWHQSLFYALFQS-STTRSAGLQTIDVSHFSDATNIVMGLLMFIGSSPSSVGGGIRTTTFAILILFVIN 330
Cdd:COG0168  223 LWNNGT---LGSLGEALRAALFQVvSILTTTGFATVDYGQWPPFSLLLLILLMFIGGSAGSTAGGIKVTRFAVLLKAIRR 299
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180 331 F----NNTGDKTGIKIFNREVHIMDVQRSFAVFTMASLITFISMIIISATEqgKLSFLQIFFEVMSAFGTCGLSLGVT-S 405
Cdd:COG0168  300 ElrrlIHPNAVRPVRIGGRRIPEEVIRKALAFFFLYLLLVVVGTLLLSLTE--GLDFLTALFEVASAFGNVGLSLGITgA 377
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|..
gi 487747180 406 DVNDITKAVLMILMFIGRVGLISFIIMLAGRkepekYSYPKE 447
Cdd:COG0168  378 SLSDAGKLVLIFLMLLGRLEILTVLVLLTPR-----FRWREE 414
 
Name Accession Description Interval E-value
TrkG COG0168
Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];
13-447 5.16e-74

Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];


Pssm-ID: 439938 [Multi-domain]  Cd Length: 414  Bit Score: 238.06  E-value: 5.16e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  13 PQQGIILYYLFAIVVAFLLLNLPYVHKqGVEVNPIDTLFVAVSGISVTGLSPITIVDTYSTFGQIIILIILNIGGIGVMA 92
Cdd:COG0168    1 PAREGFLIVALVWLVGALLLALPFALS-GGGLSFLDALFEAVSGVTTTGLTVVDTLDTLPKFGLLWRSLLQWLGGLGIIV 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  93 IGTMLWVVLGkhigIRERQLIMLD-NNRDTMSGTVKLILEIVRTIFIIEFIGALLLAFYfyrdnpdlKNALMQGIFVSVS 171
Cdd:COG0168   80 LAVAILPLLG----IGGRQLFQAElPNEKLLPRIVRTAKALWLIYLGLTLIGALLLWLA--------GMALFDAIFHAFS 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180 172 ATTNGGLDITGESLVPYAkDYFVQTIVMFLIVLGSIGFPVLLELKAYIKNRvtnfRFSLFTKITTTTYLFLFLFGVIVVL 251
Cdd:COG0168  148 AFSTGGFSTHDDSLGAFN-SPAIELVIIVFMILGGLGFPVHYDLLRYRRFR----RLFSDTELRLYLTLILLVVGLLALF 222
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180 252 ILEHSNafkGLSWHQSLFYALFQS-STTRSAGLQTIDVSHFSDATNIVMGLLMFIGSSPSSVGGGIRTTTFAILILFVIN 330
Cdd:COG0168  223 LWNNGT---LGSLGEALRAALFQVvSILTTTGFATVDYGQWPPFSLLLLILLMFIGGSAGSTAGGIKVTRFAVLLKAIRR 299
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180 331 F----NNTGDKTGIKIFNREVHIMDVQRSFAVFTMASLITFISMIIISATEqgKLSFLQIFFEVMSAFGTCGLSLGVT-S 405
Cdd:COG0168  300 ElrrlIHPNAVRPVRIGGRRIPEEVIRKALAFFFLYLLLVVVGTLLLSLTE--GLDFLTALFEVASAFGNVGLSLGITgA 377
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|..
gi 487747180 406 DVNDITKAVLMILMFIGRVGLISFIIMLAGRkepekYSYPKE 447
Cdd:COG0168  378 SLSDAGKLVLIFLMLLGRLEILTVLVLLTPR-----FRWREE 414
2a38 TIGR00933
potassium uptake protein, TrkH family; The proteins of the Trk family are derived from ...
31-423 1.45e-58

potassium uptake protein, TrkH family; The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273349  Cd Length: 391  Bit Score: 197.11  E-value: 1.45e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180   31 LLNLPYVHKQGVEVNPIDTLFVAVSGISVTGLSPITIVDTYSTFGQIIILIILNIGGIGVMAIGTMLWVVLGKHIGIRER 110
Cdd:TIGR00933   1 LLALPFVISSGLPLSFIDALFTATSAVTTTGLTVLDTLESLPKAGLFLRSLLQQIGGLGFMVLAVAILILLGKKISLGAR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  111 QLIMLDNNRDTMSGTVKLILEIVRTIFIIEFIGALLLAFYFYrdnPDLKNALMQGIFVSVSATTNGGLDITGESLVPYAK 190
Cdd:TIGR00933  81 LYLAEALGPLSDDKLLPLIKNTAKFIFVIYLLGTILLAVRFV---LTGWMPLFDAIFHSISAFNNGGFSTHSDSSIGYFH 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  191 DYFVQTIVMFLIVLGSIGFPVLLELKAYIKNRVtNFRFSLFTKITTTTYLFLFLFGVIVVLILEHSNAFKGLSWHQSLFY 270
Cdd:TIGR00933 158 DPSVNLVIAFLIILGGLGFTVHYDVYLHLRKRV-FKSLSLDTKVRLFVTFLLLAIGFILFLLLERGNTLYSYSFGALLLS 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  271 ALFQSSTTRSAGLQTIDVSHFSDATNIVMGLLMFIGSSPSSVGGGIRTTTFAILILFVINFNNTGDKTGIkIFNREVHIM 350
Cdd:TIGR00933 237 AFFQSSTLRTAGFSTIDFAALPTATLVLLLLLMFIGGCSGSTAGGIKTTTFAILLKQVYREIRRGIHPRI-IFSRRIGGK 315
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 487747180  351 DVQRSFAVFTMASLITFISMIIISATE--QGKLSFLQIFFEVMSAFGTCGLSLGVTS-DVNDITKAVLMILMFIGR 423
Cdd:TIGR00933 316 TIDKAILISVWSFFLVFALIFLLSILEliSSGYDFLTSLFEVVSAFGTVGLSVGLTTaNLPDAGKLILIVLMFIGR 391
TrkH pfam02386
Cation transport protein; This family consists of various cation transport proteins (Trk) and ...
47-431 8.88e-42

Cation transport protein; This family consists of various cation transport proteins (Trk) and V-type sodium ATP synthase subunit J or translocating ATPase J EC:3.6.1.34. These proteins are involved in active sodium up-take utilizing ATP in the process. TrkH a member of the family from E. coli is a hydrophobic membrane protein and determines the specificity and kinetics of cation transport by the TrK system in E. coli.


Pssm-ID: 280534  Cd Length: 491  Bit Score: 154.89  E-value: 8.88e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180   47 IDTLFVAVSGISVTGLSPITIVDTYSTFGQIIILIILNIGGIGVMAIGTMLWVVLGKHIGIRERQLIMLDNNRDTMSGTV 126
Cdd:pfam02386  64 LDALFEAVSGLTTTGLTVIDVETSLPRSGLFYRAQLQWIGGLGTMVLAVLSWPTLGRGSAFLYLSEMQGPELGGKEYPSL 143
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  127 KLILEIVRTIFIIEFIGALLLAFYFYRDNPDLKNA--LMQGIFVSVSATTNGGLDITGESLVPYAKDYFVQTIVMFLIVL 204
Cdd:pfam02386 144 SELCKILWVYYFGLTILAFVAYFVFIYTAKGYLEVvpLWWAFFHSMSAFSNGGFSLTPNSIASFNTNPVILWVATSFIIL 223
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  205 GSIGFPVLLELKAYIKNRVTNFR-----FSLFTKITTTTYLFLFLFGVIVVLILE-----------------HSNAFKGL 262
Cdd:pfam02386 224 GGIGFPIHLRVIIWIMKKILRFKnfkesLSLLLDHPRRCFTLLFASGFTWVLFLElavlnvtdwilfmvldfGSHVVGSI 303
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  263 SWHQSLFYALFQSSTTRSAGLQTIDVSHFSDATNIVMGLLMFIGSSPSSVGGGIRTTTFAILILFVINFNNtGDKTGIKI 342
Cdd:pfam02386 304 PKGYRVLNAFFQSVSTRTAGFSVVDISNLHPAIKVSYVLMMFIGGAPGSTAGGIKRTRVYEEFSLGKYEIH-GDPEPRAV 382
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  343 FNREVHIMDVQRS-----FAVFTMASLITFISMIIISatEQGKLSFLQIFFEVMSAFGTCGLSLG----VTSDVNDITKA 413
Cdd:pfam02386 383 STKSIDGKHLTRQlsedlWYLFLGLFIICICEGLKLS--DVGPFSFFDILFEVVSAYGTVGLSLGtnhsLSAQFTTIAKL 460
                         410
                  ....*....|....*...
gi 487747180  414 VLMILMFIGRVGLISFII 431
Cdd:pfam02386 461 VIIALMIRGRLEGLPVLL 478
 
Name Accession Description Interval E-value
TrkG COG0168
Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];
13-447 5.16e-74

Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];


Pssm-ID: 439938 [Multi-domain]  Cd Length: 414  Bit Score: 238.06  E-value: 5.16e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  13 PQQGIILYYLFAIVVAFLLLNLPYVHKqGVEVNPIDTLFVAVSGISVTGLSPITIVDTYSTFGQIIILIILNIGGIGVMA 92
Cdd:COG0168    1 PAREGFLIVALVWLVGALLLALPFALS-GGGLSFLDALFEAVSGVTTTGLTVVDTLDTLPKFGLLWRSLLQWLGGLGIIV 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  93 IGTMLWVVLGkhigIRERQLIMLD-NNRDTMSGTVKLILEIVRTIFIIEFIGALLLAFYfyrdnpdlKNALMQGIFVSVS 171
Cdd:COG0168   80 LAVAILPLLG----IGGRQLFQAElPNEKLLPRIVRTAKALWLIYLGLTLIGALLLWLA--------GMALFDAIFHAFS 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180 172 ATTNGGLDITGESLVPYAkDYFVQTIVMFLIVLGSIGFPVLLELKAYIKNRvtnfRFSLFTKITTTTYLFLFLFGVIVVL 251
Cdd:COG0168  148 AFSTGGFSTHDDSLGAFN-SPAIELVIIVFMILGGLGFPVHYDLLRYRRFR----RLFSDTELRLYLTLILLVVGLLALF 222
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180 252 ILEHSNafkGLSWHQSLFYALFQS-STTRSAGLQTIDVSHFSDATNIVMGLLMFIGSSPSSVGGGIRTTTFAILILFVIN 330
Cdd:COG0168  223 LWNNGT---LGSLGEALRAALFQVvSILTTTGFATVDYGQWPPFSLLLLILLMFIGGSAGSTAGGIKVTRFAVLLKAIRR 299
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180 331 F----NNTGDKTGIKIFNREVHIMDVQRSFAVFTMASLITFISMIIISATEqgKLSFLQIFFEVMSAFGTCGLSLGVT-S 405
Cdd:COG0168  300 ElrrlIHPNAVRPVRIGGRRIPEEVIRKALAFFFLYLLLVVVGTLLLSLTE--GLDFLTALFEVASAFGNVGLSLGITgA 377
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|..
gi 487747180 406 DVNDITKAVLMILMFIGRVGLISFIIMLAGRkepekYSYPKE 447
Cdd:COG0168  378 SLSDAGKLVLIFLMLLGRLEILTVLVLLTPR-----FRWREE 414
2a38 TIGR00933
potassium uptake protein, TrkH family; The proteins of the Trk family are derived from ...
31-423 1.45e-58

potassium uptake protein, TrkH family; The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273349  Cd Length: 391  Bit Score: 197.11  E-value: 1.45e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180   31 LLNLPYVHKQGVEVNPIDTLFVAVSGISVTGLSPITIVDTYSTFGQIIILIILNIGGIGVMAIGTMLWVVLGKHIGIRER 110
Cdd:TIGR00933   1 LLALPFVISSGLPLSFIDALFTATSAVTTTGLTVLDTLESLPKAGLFLRSLLQQIGGLGFMVLAVAILILLGKKISLGAR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  111 QLIMLDNNRDTMSGTVKLILEIVRTIFIIEFIGALLLAFYFYrdnPDLKNALMQGIFVSVSATTNGGLDITGESLVPYAK 190
Cdd:TIGR00933  81 LYLAEALGPLSDDKLLPLIKNTAKFIFVIYLLGTILLAVRFV---LTGWMPLFDAIFHSISAFNNGGFSTHSDSSIGYFH 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  191 DYFVQTIVMFLIVLGSIGFPVLLELKAYIKNRVtNFRFSLFTKITTTTYLFLFLFGVIVVLILEHSNAFKGLSWHQSLFY 270
Cdd:TIGR00933 158 DPSVNLVIAFLIILGGLGFTVHYDVYLHLRKRV-FKSLSLDTKVRLFVTFLLLAIGFILFLLLERGNTLYSYSFGALLLS 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  271 ALFQSSTTRSAGLQTIDVSHFSDATNIVMGLLMFIGSSPSSVGGGIRTTTFAILILFVINFNNTGDKTGIkIFNREVHIM 350
Cdd:TIGR00933 237 AFFQSSTLRTAGFSTIDFAALPTATLVLLLLLMFIGGCSGSTAGGIKTTTFAILLKQVYREIRRGIHPRI-IFSRRIGGK 315
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 487747180  351 DVQRSFAVFTMASLITFISMIIISATE--QGKLSFLQIFFEVMSAFGTCGLSLGVTS-DVNDITKAVLMILMFIGR 423
Cdd:TIGR00933 316 TIDKAILISVWSFFLVFALIFLLSILEliSSGYDFLTSLFEVVSAFGTVGLSVGLTTaNLPDAGKLILIVLMFIGR 391
TrkH pfam02386
Cation transport protein; This family consists of various cation transport proteins (Trk) and ...
47-431 8.88e-42

Cation transport protein; This family consists of various cation transport proteins (Trk) and V-type sodium ATP synthase subunit J or translocating ATPase J EC:3.6.1.34. These proteins are involved in active sodium up-take utilizing ATP in the process. TrkH a member of the family from E. coli is a hydrophobic membrane protein and determines the specificity and kinetics of cation transport by the TrK system in E. coli.


Pssm-ID: 280534  Cd Length: 491  Bit Score: 154.89  E-value: 8.88e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180   47 IDTLFVAVSGISVTGLSPITIVDTYSTFGQIIILIILNIGGIGVMAIGTMLWVVLGKHIGIRERQLIMLDNNRDTMSGTV 126
Cdd:pfam02386  64 LDALFEAVSGLTTTGLTVIDVETSLPRSGLFYRAQLQWIGGLGTMVLAVLSWPTLGRGSAFLYLSEMQGPELGGKEYPSL 143
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  127 KLILEIVRTIFIIEFIGALLLAFYFYRDNPDLKNA--LMQGIFVSVSATTNGGLDITGESLVPYAKDYFVQTIVMFLIVL 204
Cdd:pfam02386 144 SELCKILWVYYFGLTILAFVAYFVFIYTAKGYLEVvpLWWAFFHSMSAFSNGGFSLTPNSIASFNTNPVILWVATSFIIL 223
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  205 GSIGFPVLLELKAYIKNRVTNFR-----FSLFTKITTTTYLFLFLFGVIVVLILE-----------------HSNAFKGL 262
Cdd:pfam02386 224 GGIGFPIHLRVIIWIMKKILRFKnfkesLSLLLDHPRRCFTLLFASGFTWVLFLElavlnvtdwilfmvldfGSHVVGSI 303
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  263 SWHQSLFYALFQSSTTRSAGLQTIDVSHFSDATNIVMGLLMFIGSSPSSVGGGIRTTTFAILILFVINFNNtGDKTGIKI 342
Cdd:pfam02386 304 PKGYRVLNAFFQSVSTRTAGFSVVDISNLHPAIKVSYVLMMFIGGAPGSTAGGIKRTRVYEEFSLGKYEIH-GDPEPRAV 382
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  343 FNREVHIMDVQRS-----FAVFTMASLITFISMIIISatEQGKLSFLQIFFEVMSAFGTCGLSLG----VTSDVNDITKA 413
Cdd:pfam02386 383 STKSIDGKHLTRQlsedlWYLFLGLFIICICEGLKLS--DVGPFSFFDILFEVVSAYGTVGLSLGtnhsLSAQFTTIAKL 460
                         410
                  ....*....|....*...
gi 487747180  414 VLMILMFIGRVGLISFII 431
Cdd:pfam02386 461 VIIALMIRGRLEGLPVLL 478
2a38euk TIGR00934
potassium uptake protein, Trk family; The proteins of the Trk family are derived from ...
126-423 1.41e-23

potassium uptake protein, Trk family; The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. This family is specific for the eukaryotic Trk system. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130009 [Multi-domain]  Cd Length: 800  Bit Score: 103.91  E-value: 1.41e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  126 VKLILEIVRTIFIIEFIGALLLAFYF------YRDNPDLK--NALMQGIFVSVSATTNGGLDITGESLVPYAKDYFVQTI 197
Cdd:TIGR00934 448 LKCLCSIVLVYFLGFNILGFVLLLPWinhvktYSEVVRSKgvSPTWWGFFTAMSAFANLGLTLTPESMVSFNKNSYLLLL 527
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  198 VMFLIVLGSIGFPVLLELKAYIKNRVTNF-----------------RFSLFTKITTTTYLFLFLFG-----VIVVLILE- 254
Cdd:TIGR00934 528 MIWFIIIGNTGFPIFLRLIIWILFKISPDlskrkeslgflldhprrCFTLLFPSGATWWLFFTLVGlnaidLILFIILDw 607
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  255 HSNAFKGLSWHQSLFYALFQSSTTRSAGLQTIDVSHFSDATNIVMGLLMFIGSSPSSVGGGiRTTTFAILILFVINFNNT 334
Cdd:TIGR00934 608 GSSVVDGLSKGIKVLNGLFQSVSTRTAGFTVVDLSQLHPAIQVSYMLMMYVSVLPLAISIR-RTNVYEEQSLGLYNEENE 686
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487747180  335 GDKTGIKIFNREVHIMDVQRSFAVFTMaslitFISMIIISATEQGKL--------SFLQIFFEVMSAFGTCGLSLGVTSD 406
Cdd:TIGR00934 687 EHEGESSTKSFIGAHLRRQLSFDLWYI-----FLGLFIICICEGRKIqdpdppnfNVFNILFEVVSAYGTVGLSLGYSCS 761
                         330       340
                  ....*....|....*....|....
gi 487747180  407 -------VNDITKAVLMILMFIGR 423
Cdd:TIGR00934 762 nysfsgqFTTLSKLVIIAMLIRGR 785
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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