|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15445 |
PRK15445 |
arsenical efflux pump membrane protein ArsB; |
4-430 |
0e+00 |
|
arsenical efflux pump membrane protein ArsB;
Pssm-ID: 185342 Cd Length: 427 Bit Score: 681.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 4 FFAVGIFLLTLLFVIWQPRGLSIGWTAVGGAILALLFGVVSFKDVGTVTGIVWNATLSFVAIILISLILDQIGFFEWAAL 83
Cdd:PRK15445 1 LLAIAIFLLTLVLVIWQPKGLGIGWSALLGAVLALLTGVVSLGDVPVVWGIVWNATLTFIAIIIISLLLDEAGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 84 HMARWANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDEKQVFPFIIASGFIADTTSLPMIVSNLVN 163
Cdd:PRK15445 81 HVARWAKGNGRKLFVYIVLLGAAVAALFANDGAALILTPIVLAMLLALGFSKKATLAFVMAAGFIADTASLPLVVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 164 IVSADFFGISFSAYALRMWIPDLFSLLGSIGILYLYFRKALPRKFDATQVAEPSSALKDQRLFKFSWVVLILLLIGYFSS 243
Cdd:PRK15445 161 IVSADYFGIGFAEYASVMVPVNLVSLAASLLVLWLYFRKDIPKTYDLELLKEPASAIKDPALFKLGWIVLALLLVGYFVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 244 GFLGIPVSFIALSIAAIFLIVGQRSSHVNAMAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFAAT 323
Cdd:PRK15445 241 EPLGIPVSAIAGVGALILLLVARRGHAINTKKVLKGAPWQIVIFSLGMYLVVYGLRNAGLTDYLAGVLNYLADQGLFAAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 324 MGMGYLAALLSSLMNNMPTVMINALSIKGADVSGLIHHTLVYANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIKWGT 403
Cdd:PRK15445 321 LGTGFLAAFLSSVMNNMPTVLIGALAIDGSNATGVIKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*..
gi 489677876 404 YFKIGIVTTIPVLFITLCGLWLSLSIF 430
Cdd:PRK15445 401 YFKVGIIITLPVLLVTLLALALRLSLF 427
|
|
| 2a45 |
TIGR00935 |
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a ... |
4-429 |
0e+00 |
|
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a highly hydrophobic integral membrane protein involved in transport processes used to protect cells from arsenite (or antimonite). Members of the seed alignment were selected by adjacency to the ATPase subunit ArsA that energizes the transport. [Cellular processes, Detoxification, Transport and binding proteins, Other]
Pssm-ID: 213571 Cd Length: 426 Bit Score: 616.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 4 FFAVGIFLLTLLFVIWQPRGLSIGWTAVGGAILALLFGVVSFKDVGTVTGIVWNATLSFVAIILISLILDQIGFFEWAAL 83
Cdd:TIGR00935 1 ILAVLIFLLTLVLVIWQPKGLGIGWSATIGAVLALLSGVVSFGDVPVVTGIVWNATLTFVAIIIISLILDEIGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 84 HMARWANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDEKQVFPFIIASGFIADTTSLPMIVSNLVN 163
Cdd:TIGR00935 81 HMARWAKGNGRKMFIYISLLGAIVAALFANDGAALILTPIVLAMVRALGFDEAAVLPFIMASGFIADTTSLPLIVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 164 IVSADFFGISFSAYALRMWIPDLFSLLGSIGILYLYFRKALPRKFDATQVAEPSSALKDQRLFKFSWVVLILLLIGYFSS 243
Cdd:TIGR00935 161 IVSADFFGIGFNEYAAVMIPPNIFALIASILVLYLYFRKDIPARYDVSQLREPKEAIKDQKLFKFSWVVLALLLVGYFGS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 244 GFLGIPVSFIALSIAAIFLIVGQRSSHVNAMAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFAAT 323
Cdd:TIGR00935 241 EFLNIPVSFVAATIALIFLVVAAKSHAVDTRKVIKGAPWNIVVFSLGMYLVVYGLRNVGLTDLLAGVLDYFADQGLFVAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 324 MGMGYLAALLSSLMNNMPTVMINALSIKGADVSGLIHHTLVYANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIKWGT 403
Cdd:TIGR00935 321 MGMGFLAAFLSSIMNNMPTVLINALSIDGSNATGVMKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*.
gi 489677876 404 YFKIGIVTTIPVLFITLCGLWLSLSI 429
Cdd:TIGR00935 401 YFKVGIVITVPVLFITLAGLYLRLSI 426
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
6-424 |
1.26e-148 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 428.61 E-value: 1.26e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 6 AVGIFLLTLLFVIWQPRGLSIGWTAVGGAILALLFGVVSFKDVGTVTGIVWNATLSFVAIILISLILDQIGFFEWAALHM 85
Cdd:cd01118 2 AIAIFVLTLVLVIWRPFGLPEAVWAVLGAVIALILGLVSPHDALEVWGIVWDVTLTLIGVILLSLLLDEEGFFEWVAALA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 86 ARWANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDEKQVFPFIIASGFIADTTSLPMIVSNLVNIV 165
Cdd:cd01118 82 ARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKNRTLPFLYACAFIADAASLPLPISNLVNIV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 166 SADFFGISFSAYALRMWIPDLFSLLGSIGILYLYFRKALPRKFDATQVAEPSSALKDQRLFKFSWVVLILLLIGYFSSGF 245
Cdd:cd01118 162 TAGYFGIGFTEYAALMFLPSIVSILATYVVLYLFFRRALPKRLETASVKKPSLAIKDPLLFGLAWTLLVLLVVSAFGVDI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 246 LGIPVSFIALSIAAIFLIVGQRSSHVNAMAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFAATMG 325
Cdd:cd01118 242 LLIPPSFIAGVLALIFLLLARRGGAINPLKVLKEAPWGVLLFSLGLYVVVFGLKNAGLTAILADLLNWLVSQGLLAAILG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 326 MGYLAALLSSLMNNMPTVMINALSIKGADVSGlihhTLVYANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIKWGTYF 405
Cdd:cd01118 322 VGLLAAFLSNVMNNLPAVLIGALALAAGHAPE----ALVYANLIGVDLGPKLTPIGSLATLLWLHVLRRKGIRVSWGYYL 397
|
410
....*....|....*....
gi 489677876 406 KIGIVTTIPVLFITLCGLW 424
Cdd:cd01118 398 KVGLIVTPPVLVVTLAALI 416
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
2-427 |
1.75e-112 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 336.33 E-value: 1.75e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 2 QVFFAVGIFLLTLLFVIWQPRGLSIGWTAVGGAILALLFGVVSFKDVgtVTGIVWNATLSFVAIILISLILDQIGFFEWA 81
Cdd:COG1055 1 MMILALAIFVLTYLLIILEPRGLNRAVAALLGAALLLLLGVVSLEDA--LEAIDWNTILFLLGMMIIVAILDESGFFEWL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 82 ALHMARWANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDekqVFPFIIASGFIADTTSLPMIVSNL 161
Cdd:COG1055 79 AIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLN---PVPFLIAIVFAANIGGAATPIGNP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 162 VNIVSADFFGISFSAYALRMWIPDLFSLLGSIGILYLYFRKALPRKFDATQvaEPSSALKDQRLFKFSWVVLILLLIGYF 241
Cdd:COG1055 156 TNIMIASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPAAPDLED--DPKEAIKDRRLLRISLLVLALLLVGFV 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 242 SSGFLGIPVSFIALSIAAIFLIVgqrsSHVNAMAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFA 321
Cdd:COG1055 234 LHSFLGLPPALIALLGAAVLLLL----ARVDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLL 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 322 ATMGMGYLAALLSSLMNNMPTVMINALSIKGADVSGlIHHTLVYANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIKW 401
Cdd:COG1055 310 AALLILWLSAILSAVVDNVPLVAALLPLIPDLGATG-NPEPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISF 388
|
410 420
....*....|....*....|....*.
gi 489677876 402 GTYFKIGIVTTIPVLFITLCGLWLSL 427
Cdd:COG1055 389 GEFLKVGLPLTLLTLLIALLYLLLLY 414
|
|
| ArsB |
pfam02040 |
Arsenical pump membrane protein; |
6-427 |
2.53e-112 |
|
Arsenical pump membrane protein;
Pssm-ID: 460426 Cd Length: 423 Bit Score: 336.57 E-value: 2.53e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 6 AVGIFLLTLLFVIWQPRGLSIGWTAVGGAILALLFGVVSFKDVGTVTGIVWNATLSFVAIILISLILDQIGFFEWAALHM 85
Cdd:pfam02040 2 ASFIFALFIFLLILQLKILQIGNLACGGAACAGAAGALIAGDVLFHDGITVNAILAFAAIAFIAIILDNIGFDEIAAFEM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 86 ARWANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDEKQVFPFIIASGFIADTTSLPMIVSNLVNIV 165
Cdd:pfam02040 82 AAAAKAKAAKGFGVRMFLGAILAAAFAAAGAALDGAAIILAMIRAAHFNAKHFFEFIIAPFFIADGFIADFTSLNFVNIN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 166 SADFFGISFSAYALRMWIPDLFSLLGSIGILYLYFRKALPRKFDATQVAEPSSALKDQRLFKFSWVVLILLLIGYFSSGF 245
Cdd:pfam02040 162 LADIFHADFFDIAFIDVAPRLFSLLAFIILASIFFLKLFFKKSDLKEVDKPEEAIKDEAIFDLNMFILGLLIIGLFAIEF 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 246 LGIPVSFIALSIAAIFLIVGQRSSHVNAMAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFAATMG 325
Cdd:pfam02040 242 FAIEFFSIAGSIAAGFIAAAFKIAAQHSKAVHKEAPVAEAFFAIGFFSIGMGVRNAGLRDAGLDDILAAADQAAAAGGIF 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 326 MGYLAALLSSLMNNMPTVMINALSIKGADVSGLIHHTLVYANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIKWGTYF 405
Cdd:pfam02040 322 AGFIAAGFIAAILNLIMNMIDALAIAALAIAGMDREALIRAALIGADLGGKDLGIGILAIGLLAHLLSHHGLKHKGGKIF 401
|
410 420
....*....|....*....|..
gi 489677876 406 KIGIVTTIPVLFITLCGLWLSL 427
Cdd:pfam02040 402 KGGIFKTGIILLIPLLGITIVG 423
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15445 |
PRK15445 |
arsenical efflux pump membrane protein ArsB; |
4-430 |
0e+00 |
|
arsenical efflux pump membrane protein ArsB;
Pssm-ID: 185342 Cd Length: 427 Bit Score: 681.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 4 FFAVGIFLLTLLFVIWQPRGLSIGWTAVGGAILALLFGVVSFKDVGTVTGIVWNATLSFVAIILISLILDQIGFFEWAAL 83
Cdd:PRK15445 1 LLAIAIFLLTLVLVIWQPKGLGIGWSALLGAVLALLTGVVSLGDVPVVWGIVWNATLTFIAIIIISLLLDEAGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 84 HMARWANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDEKQVFPFIIASGFIADTTSLPMIVSNLVN 163
Cdd:PRK15445 81 HVARWAKGNGRKLFVYIVLLGAAVAALFANDGAALILTPIVLAMLLALGFSKKATLAFVMAAGFIADTASLPLVVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 164 IVSADFFGISFSAYALRMWIPDLFSLLGSIGILYLYFRKALPRKFDATQVAEPSSALKDQRLFKFSWVVLILLLIGYFSS 243
Cdd:PRK15445 161 IVSADYFGIGFAEYASVMVPVNLVSLAASLLVLWLYFRKDIPKTYDLELLKEPASAIKDPALFKLGWIVLALLLVGYFVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 244 GFLGIPVSFIALSIAAIFLIVGQRSSHVNAMAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFAAT 323
Cdd:PRK15445 241 EPLGIPVSAIAGVGALILLLVARRGHAINTKKVLKGAPWQIVIFSLGMYLVVYGLRNAGLTDYLAGVLNYLADQGLFAAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 324 MGMGYLAALLSSLMNNMPTVMINALSIKGADVSGLIHHTLVYANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIKWGT 403
Cdd:PRK15445 321 LGTGFLAAFLSSVMNNMPTVLIGALAIDGSNATGVIKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*..
gi 489677876 404 YFKIGIVTTIPVLFITLCGLWLSLSIF 430
Cdd:PRK15445 401 YFKVGIIITLPVLLVTLLALALRLSLF 427
|
|
| 2a45 |
TIGR00935 |
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a ... |
4-429 |
0e+00 |
|
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a highly hydrophobic integral membrane protein involved in transport processes used to protect cells from arsenite (or antimonite). Members of the seed alignment were selected by adjacency to the ATPase subunit ArsA that energizes the transport. [Cellular processes, Detoxification, Transport and binding proteins, Other]
Pssm-ID: 213571 Cd Length: 426 Bit Score: 616.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 4 FFAVGIFLLTLLFVIWQPRGLSIGWTAVGGAILALLFGVVSFKDVGTVTGIVWNATLSFVAIILISLILDQIGFFEWAAL 83
Cdd:TIGR00935 1 ILAVLIFLLTLVLVIWQPKGLGIGWSATIGAVLALLSGVVSFGDVPVVTGIVWNATLTFVAIIIISLILDEIGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 84 HMARWANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDEKQVFPFIIASGFIADTTSLPMIVSNLVN 163
Cdd:TIGR00935 81 HMARWAKGNGRKMFIYISLLGAIVAALFANDGAALILTPIVLAMVRALGFDEAAVLPFIMASGFIADTTSLPLIVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 164 IVSADFFGISFSAYALRMWIPDLFSLLGSIGILYLYFRKALPRKFDATQVAEPSSALKDQRLFKFSWVVLILLLIGYFSS 243
Cdd:TIGR00935 161 IVSADFFGIGFNEYAAVMIPPNIFALIASILVLYLYFRKDIPARYDVSQLREPKEAIKDQKLFKFSWVVLALLLVGYFGS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 244 GFLGIPVSFIALSIAAIFLIVGQRSSHVNAMAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFAAT 323
Cdd:TIGR00935 241 EFLNIPVSFVAATIALIFLVVAAKSHAVDTRKVIKGAPWNIVVFSLGMYLVVYGLRNVGLTDLLAGVLDYFADQGLFVAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 324 MGMGYLAALLSSLMNNMPTVMINALSIKGADVSGLIHHTLVYANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIKWGT 403
Cdd:TIGR00935 321 MGMGFLAAFLSSIMNNMPTVLINALSIDGSNATGVMKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*.
gi 489677876 404 YFKIGIVTTIPVLFITLCGLWLSLSI 429
Cdd:TIGR00935 401 YFKVGIVITVPVLFITLAGLYLRLSI 426
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
6-424 |
1.26e-148 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 428.61 E-value: 1.26e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 6 AVGIFLLTLLFVIWQPRGLSIGWTAVGGAILALLFGVVSFKDVGTVTGIVWNATLSFVAIILISLILDQIGFFEWAALHM 85
Cdd:cd01118 2 AIAIFVLTLVLVIWRPFGLPEAVWAVLGAVIALILGLVSPHDALEVWGIVWDVTLTLIGVILLSLLLDEEGFFEWVAALA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 86 ARWANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDEKQVFPFIIASGFIADTTSLPMIVSNLVNIV 165
Cdd:cd01118 82 ARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKNRTLPFLYACAFIADAASLPLPISNLVNIV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 166 SADFFGISFSAYALRMWIPDLFSLLGSIGILYLYFRKALPRKFDATQVAEPSSALKDQRLFKFSWVVLILLLIGYFSSGF 245
Cdd:cd01118 162 TAGYFGIGFTEYAALMFLPSIVSILATYVVLYLFFRRALPKRLETASVKKPSLAIKDPLLFGLAWTLLVLLVVSAFGVDI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 246 LGIPVSFIALSIAAIFLIVGQRSSHVNAMAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFAATMG 325
Cdd:cd01118 242 LLIPPSFIAGVLALIFLLLARRGGAINPLKVLKEAPWGVLLFSLGLYVVVFGLKNAGLTAILADLLNWLVSQGLLAAILG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 326 MGYLAALLSSLMNNMPTVMINALSIKGADVSGlihhTLVYANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIKWGTYF 405
Cdd:cd01118 322 VGLLAAFLSNVMNNLPAVLIGALALAAGHAPE----ALVYANLIGVDLGPKLTPIGSLATLLWLHVLRRKGIRVSWGYYL 397
|
410
....*....|....*....
gi 489677876 406 KIGIVTTIPVLFITLCGLW 424
Cdd:cd01118 398 KVGLIVTPPVLVVTLAALI 416
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
2-427 |
1.75e-112 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 336.33 E-value: 1.75e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 2 QVFFAVGIFLLTLLFVIWQPRGLSIGWTAVGGAILALLFGVVSFKDVgtVTGIVWNATLSFVAIILISLILDQIGFFEWA 81
Cdd:COG1055 1 MMILALAIFVLTYLLIILEPRGLNRAVAALLGAALLLLLGVVSLEDA--LEAIDWNTILFLLGMMIIVAILDESGFFEWL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 82 ALHMARWANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDekqVFPFIIASGFIADTTSLPMIVSNL 161
Cdd:COG1055 79 AIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLN---PVPFLIAIVFAANIGGAATPIGNP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 162 VNIVSADFFGISFSAYALRMWIPDLFSLLGSIGILYLYFRKALPRKFDATQvaEPSSALKDQRLFKFSWVVLILLLIGYF 241
Cdd:COG1055 156 TNIMIASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPAAPDLED--DPKEAIKDRRLLRISLLVLALLLVGFV 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 242 SSGFLGIPVSFIALSIAAIFLIVgqrsSHVNAMAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFA 321
Cdd:COG1055 234 LHSFLGLPPALIALLGAAVLLLL----ARVDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLL 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 322 ATMGMGYLAALLSSLMNNMPTVMINALSIKGADVSGlIHHTLVYANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIKW 401
Cdd:COG1055 310 AALLILWLSAILSAVVDNVPLVAALLPLIPDLGATG-NPEPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISF 388
|
410 420
....*....|....*....|....*.
gi 489677876 402 GTYFKIGIVTTIPVLFITLCGLWLSL 427
Cdd:COG1055 389 GEFLKVGLPLTLLTLLIALLYLLLLY 414
|
|
| ArsB |
pfam02040 |
Arsenical pump membrane protein; |
6-427 |
2.53e-112 |
|
Arsenical pump membrane protein;
Pssm-ID: 460426 Cd Length: 423 Bit Score: 336.57 E-value: 2.53e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 6 AVGIFLLTLLFVIWQPRGLSIGWTAVGGAILALLFGVVSFKDVGTVTGIVWNATLSFVAIILISLILDQIGFFEWAALHM 85
Cdd:pfam02040 2 ASFIFALFIFLLILQLKILQIGNLACGGAACAGAAGALIAGDVLFHDGITVNAILAFAAIAFIAIILDNIGFDEIAAFEM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 86 ARWANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDEKQVFPFIIASGFIADTTSLPMIVSNLVNIV 165
Cdd:pfam02040 82 AAAAKAKAAKGFGVRMFLGAILAAAFAAAGAALDGAAIILAMIRAAHFNAKHFFEFIIAPFFIADGFIADFTSLNFVNIN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 166 SADFFGISFSAYALRMWIPDLFSLLGSIGILYLYFRKALPRKFDATQVAEPSSALKDQRLFKFSWVVLILLLIGYFSSGF 245
Cdd:pfam02040 162 LADIFHADFFDIAFIDVAPRLFSLLAFIILASIFFLKLFFKKSDLKEVDKPEEAIKDEAIFDLNMFILGLLIIGLFAIEF 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 246 LGIPVSFIALSIAAIFLIVGQRSSHVNAMAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFAATMG 325
Cdd:pfam02040 242 FAIEFFSIAGSIAAGFIAAAFKIAAQHSKAVHKEAPVAEAFFAIGFFSIGMGVRNAGLRDAGLDDILAAADQAAAAGGIF 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 326 MGYLAALLSSLMNNMPTVMINALSIKGADVSGLIHHTLVYANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIKWGTYF 405
Cdd:pfam02040 322 AGFIAAGFIAAILNLIMNMIDALAIAALAIAGMDREALIRAALIGADLGGKDLGIGILAIGLLAHLLSHHGLKHKGGKIF 401
|
410 420
....*....|....*....|..
gi 489677876 406 KIGIVTTIPVLFITLCGLWLSL 427
Cdd:pfam02040 402 KGGIFKTGIILLIPLLGITIVG 423
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
16-423 |
9.08e-63 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 207.49 E-value: 9.08e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 16 FVIWQPRGLSIGWTAVGGAILALLFGVVSFKDVgtVTGIVWNATLSFVAIILISLILDQIGFFEWAALHMARWANGHGIR 95
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVSPKEA--LSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARASKGSRRL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 96 MFILVTtLGAVVAALFANDGAALILTPIVLAMVRALHFdeKQVFPFIIASGFIADTTSLPMIVSNLVNIVSADFFGISFS 175
Cdd:cd00625 79 LLLLML-LTAALSAFFSNDATAVLLTPIVLALLRKLGL--SPPVPLLLALAFAANIGGAATPIGNPPNLIIASLSGLGFL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 176 AYALRMWIPDLFSLLGSIGILYLYFRKALPRKFDATQVAEPSSALKDQRLFKFSWVVLILLLIGyFSSGFLGIPVSFIAL 255
Cdd:cd00625 156 DFLAFMAPPALGLLLLLLGLLYLLFRKKLLLPDEDKLTVLAEPLPARPLLKKFLLLALLLLLLF-VLLFFFLIPLGLIAL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 256 SIAAIFLIVGQRSSHVNamAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFAATMGMGYLAALLSS 335
Cdd:cd00625 235 LGALLLLLLLVRGLDPE--EVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLAELLVALVGLPPLAALLLIGLLSALLSN 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 336 LMNNMPTVMINALSIKGADVSGLihhtLVYANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIKWGTYFKIGIVTTIPV 415
Cdd:cd00625 313 FISNVPTVALLLPIAASLAPPEP----AWLALALGSTLGGNLTLIGSLANLIPLGAAENAGVGISFGEFLKVGLPLTLLS 388
|
....*...
gi 489677876 416 LFITLCGL 423
Cdd:cd00625 389 LVVSLLYL 396
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
14-370 |
2.52e-38 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 141.68 E-value: 2.52e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 14 LLFVIWQPrgLSIGWTAVGGAILALLFGVVSFKDVgtVTGIVWNATLSFVAIILISLILDQIGFFEWAALHMARWANGHG 93
Cdd:pfam03600 1 YVLIITEK--LPRDVVALLGAVLLVLLGVLTPEEA--LSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 94 IRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDekqVFPFIIASGFIADTTSLPMIVSNLVNIVSADFFGIS 173
Cdd:pfam03600 77 RRLLVALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLP---PSPLLIALAFAANIGGTATPIGDPPNIIIASALGLS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 174 FSAYALRMWIPDLFSLL-GSIGILYLYFRKALPRKFDATQVAEP--SSALKDQRLFKFSWVVLILLLIGYFSSGFLGIPV 250
Cdd:pfam03600 154 FGDFGFFMFPPVGVALLlVGLLPLLLIFRKLLPVRKEEEAELEElrKRAIKDKLLLAISALVLALVILGFLLLSVLALAG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 251 SFIALSIAAIflivgqrsshvNAMAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIakGGRFAATMGMGYLA 330
Cdd:pfam03600 234 ALLLLLTGVL-----------DPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGGL--SGLLVALALILWLS 300
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 489677876 331 ALLSSLMNNMPTVMINALSIKGADVSGLIH--HTLVYANIIG 370
Cdd:pfam03600 301 ALLSAFISNVPTAALMAPIIVGMAPAAGLGdpDPLAWALAVG 342
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
10-408 |
4.05e-29 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 117.74 E-value: 4.05e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 10 FLLTLLFVIWQPRGLSIGWTAVGGAILALLFGVVSFKDVGTVTGIVWNA-TLSFVAIILISlILDQIGFFEWAALHMARW 88
Cdd:cd01116 1 FIITYALIIFEKVHRTVAALAGALWLVILGLATLSPDLETIVSWVDWETlALLLGMMIIVS-ILSETGVFEYLAIWAVKI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 89 ANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALhfdEKQVFPFIIASGFIADTTSLPMIVSNLVNIVSAD 168
Cdd:cd01116 80 SKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLCEVL---GLNPVPVLISEVIAANIGGAATLIGDPPNIMIGS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 169 FFGISFSAYALRMWIPDLFSLLGSIGILYLYFRKALPRKF---DATQVAEPSSALKDQRLFKFSWVVLILLLIGYFSSGF 245
Cdd:cd01116 157 AAGLTFNDFLLHMLPSVVLALVVTFILLYFLYRNILKAREedvLALAELEPKYPIKDKVLLLKSLTILTLVIIGFVLHSP 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 246 LGIPVSFIALSIAAIFLIVGQRSSHVNAMAAIKgapWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFAATMG 325
Cdd:cd01116 237 LGVSLGWIALLGALLLLLLADKLDFEDVLSRVE---WDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVILGRIAVAVIL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 326 MGYLAALLSSLMNNMP-TVMINALSIKGADVSGLIHHTLVYANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIKWGTY 404
Cdd:cd01116 314 ILWISALLSAFIDNIPvTATMIPIVKDLASQLGIPLLPLWWALALGACLGGNGTLIGASANVVAAGIAEQHGYKISFWEF 393
|
....
gi 489677876 405 FKIG 408
Cdd:cd01116 394 LKVG 397
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
33-420 |
1.09e-24 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 104.67 E-value: 1.09e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 33 GAILALLFGVVSFKDVGTVtgIVWNATLSFVAIILISLILDQIGFFEWAALHMARWANGhGIRMFILVTTLGAVVAALFA 112
Cdd:cd01117 20 GAALMLLFGVISLEDAPAA--IDLDTIILLFGLMVVSAALELSGFFDALGSRILVKAGS-PRRLLFLLVLLSGILSALLT 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 113 NDGAALILTPIVLAMVRALHFDEKqvfPFIIASGFIADTTSLPMIVSNLVNIVSADFFGISFSAYALRMWIPDLFSLLGS 192
Cdd:cd01117 97 NDTACLVFTPIVLELARVAGLPPI---PLLLALATAANIGSAATPIGNPQNLLIASESGISFPFFLAAMAPLALLGLLLL 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 193 IGILYLYFRKALPRKFDATQVAEPSsalKDQRLFKFSWVVLILLLIGYFSSGFLGIPVSFIALSIAAIFLIVGQRSSHVn 272
Cdd:cd01117 174 LILLLVLFPGELKGLPLDKATKEEG---VGARKLAVKLLVLILLLLVAFLALLGVIPLWTAALVAAVLLLLTRLKPRRV- 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 273 amaaIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFAAtmgmgyLAALLSSLMNNMPTVMINALSIKG 352
Cdd:cd01117 250 ----LKKVDWGLLLFFAGLFILVGGFAQGLPLEGLSRLLPLLDSVLSLFL------VSIGLSQLISNVPAVLLLLPFLPS 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489677876 353 ADVSGLIhhtlvyANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIKWGTYFKIGIVTTIPVLFITL 420
Cdd:cd01117 320 ADEKDWL------LLAAGSTIAGNLTLLGSAANLIVAEAAERRGVRLSFGEFLKYGVPLTLLTAAIGI 381
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
63-345 |
3.33e-12 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 67.49 E-value: 3.33e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 63 VAIILISLILDQIGFFEWAALHMARWANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDEKQVFP-- 140
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGSEKRSKFGsa 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 141 FIIASGFIADTTSLPMIVSNLVNIVSADFF------GISFSAYALRMWIPDLFSLLGSIGILYLYFRKALPRKFDATQVA 214
Cdd:COG0471 81 LLLPIAFAASIGGMGTLIGTPPNLIAAGLLeeatgiPISFFEWMLVGLPVALVGLLLLWLVLYRLLPPEIKEVPGSKEVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 215 EPssalKDQRLFKFSW------VVLILLLIGYFSSGFLGIPVSFIALSIAAIFLIVGqrssHVNAMAAIKGAPWNIVFFS 288
Cdd:COG0471 161 RE----ELAELGPLSRrekialAIFALTVLLWITGSLHGIPIAVVALLGAVLLLLTG----VLTWKDAYKSIPWGVLLLF 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 489677876 289 IGMYVVVYGLQNVGLTTLLSGVITEIAKG-GRFAATMGMGYLAALLSSLMNNMPTVMI 345
Cdd:COG0471 233 GGGLALGAALEKTGLAAWLADALLPLLGGlSPLLLLLLLALLTLLLTEFASNTATAAL 290
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
5-201 |
4.98e-09 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 57.86 E-value: 4.98e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 5 FAVGIFLLTLLFVIWQP-RGLSIGWTAVGGAILALLFGVVSFKDVgtVTGIVWNATLSFVAIILISLILDQIGFFEWAAL 83
Cdd:COG0471 176 IALAIFALTVLLWITGSlHGIPIAVVALLGAVLLLLTGVLTWKDA--YKSIPWGVLLLFGGGLALGAALEKTGLAAWLAD 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 84 HMARWANGHGIRMFILVTTLGAVVAALFANDGA-ALILTPIVLAMVRALHFDekqVFPFIIASGFIADTTSLpMIVSNLV 162
Cdd:COG0471 254 ALLPLLGGLSPLLLLLLLALLTLLLTEFASNTAtAALLLPIAISLAQALGVN---PLPLALAVAFAASCAFL-LPVGTPP 329
|
170 180 190
....*....|....*....|....*....|....*....
gi 489677876 163 NIVSADFFGISFSAYALRMWIPDLFSLLGSIGILYLYFR 201
Cdd:COG0471 330 NAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLWWP 368
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
29-345 |
5.57e-08 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 54.51 E-value: 5.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 29 TAVGGAILALLFGVVSFKDVgtVTGIVWNATLSFVAIILISLILDQIGFFEWAALHMARWANGHGIRMFILVTTLGAVVA 108
Cdd:cd01115 21 TALLVPVLLVLLGVVPPKEA--FSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAGKGERRLLLLLMLVTAFLS 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 109 ALFANDGAALILTPIVLAMVRALHFDEKQVFPFIIASGFIADTTSLpmiVSNLVNIVSADFFG-ISFSAYALRMWIPDLF 187
Cdd:cd01115 99 AFMSNTATVAIMLPVALGLAAKLDISPSRLLMPLAFAASIGGMLTL---IGTPPNLVASGYLEsLGGQGFSFFEFTPIGL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 188 sLLGSIGILYLYFRKALprkfdatqvaepssalkdqrlfkfsWVVLILLLIGYFSSGFLGIPVSFIALSIAAIFLIVGQR 267
Cdd:cd01115 176 -PLLIIGLLYLWFIFRL-------------------------AVLIITIVLLAALAAITGLLPVSVAIAIGAIVLVFGGV 229
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489677876 268 SSHVNAMAAIkgaPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKG-GRFAATMGMGYLAALLSSLMNNMPTVMI 345
Cdd:cd01115 230 LLTKEDYKSI---DWGIIFLFAGGIPLGKALESSGAAALIAEALISLLGGlPPFAILLLLCLLTLVLTNFISNTATAVL 305
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
6-345 |
1.07e-06 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 50.76 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 6 AVGIFLLTLLF--VIWQPRGLSIGwtAVGGAILALLFGVVSFKDVGTVTGIVWNATLsfVAIILISLILDQIGFFEwaal 83
Cdd:PLN00136 15 AFGVFWMLAVFpsVPFLPIGRTAG--ALLSAVLMIVFHVISPDDAYASIDLPILGLL--FATMVVGSYLKNAGMFK---- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 84 HMAR---WANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDEKqvfPFIIASGFIADTTSLPMIVSN 160
Cdd:PLN00136 87 HLGRllaWRSQGGRDLLCRVCVVTALASALFTNDTCCVVLTEFVLELAAERNLPAK---PFLLALASSANIGSSATPIGN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 161 LVNIVSADFFGISFSAYALRMwIPDLFSLLG--SIGILYLYFR-----------------------------------KA 203
Cdd:PLN00136 164 PQNLVIAFNSKITFPKFLLGI-LPAMLAGMAvnMVMLLCMYWKdldggaelsvdgkqmeaveegrspasakstkqqspAL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 204 LPRKFDATQVAEPSSALKD----------------QRLF--KFSWVVLILLLIGYFssgfLGIPVSFIALSIAAIFLIVG 265
Cdd:PLN00136 243 LQAGLNGDGNGDMSSMMSEnistkhpwfmqctehrRKLFlkSFAYVVTVGMVVAYM----VGLNMSWTAITTAIALVVVD 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 266 QRsshvNAMAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRFAATMGMGYLAALLSSLMNNMPTVMI 345
Cdd:PLN00136 319 FR----DAEPCLDTVSYSLLVFFSGMFITVSGFNKTGLPGAIWNFMAPYSKVNSVGGISVLSVIILLLSNLASNVPTVLL 394
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
5-132 |
2.35e-03 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 39.93 E-value: 2.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489677876 5 FAVGIFLLTLL-FVIWQPRGLSIGWTAVGGAILALLFgvVSFKDVGTVTGIV-WNATLSFVAIILISLILDQIGFFEWAA 82
Cdd:cd01116 219 KSLTILTLVIIgFVLHSPLGVSLGWIALLGALLLLLL--ADKLDFEDVLSRVeWDTLLFFAGLFVLVGGLEELGIIEWIA 296
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 489677876 83 LHMARWANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALH 132
Cdd:cd01116 297 ELLVGVILGRIAVAVILILWISALLSAFIDNIPVTATMIPIVKDLASQLG 346
|
|
| |
