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Conserved domains on  [gi|491117537|ref|WP_004975992|]
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phosphoenolpyruvate--protein phosphotransferase [Haloferax gibbonsii]

Protein Classification

phosphoenolpyruvate--protein phosphotransferase( domain architecture ID 11437608)

phosphoenolpyruvate--protein phosphotransferase transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein

CATH:  3.20.20.60
EC:  2.7.3.9
Gene Ontology:  GO:0008965|GO:0009401|GO:0016772|GO:0005737
PubMed:  783139|19801641

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PtsA COG1080
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ...
 6-560 0e+00

Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];


:

Pssm-ID: 440698 [Multi-domain]  Cd Length: 571  Bit Score: 688.35  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537   6 ISGVGVTPLLGVGTVVQYD-STVDLDESERSAAGPEAELRRFEAARETAADELARERSRTAERVGTEEAEIFDAHQQFLA 84
Cdd:COG1080    1 LKGIAASPGIAIGKAFLLReEDLEVPEYTISPEDVEAEIARLEAALAKAREELEALREKAPEDLGEEEAAIFDAHLLLLE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  85 DPQITDGVETAISEDGLTAERAVSQAFEDPIATFEA-ADGMFAERADDLRDVRDRVLRILLDRDRVDLSALPEGTVLVAE 163
Cdd:COG1080   81 DPELIEEVEELIREGRYNAEWALKEVIEELAAQFEAlDDEYLRERAADIRDVGRRVLRNLLGVEAPDLSDLPEPVILVAH 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 164 RLTPSDTAQLDPDAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRLVVDGTTGDVTVD---------PD 234
Cdd:COG1080  161 DLTPSDTAQLDPSRVAGFVTDLGGRTSHTAILARSLGIPAVVGLGDALLLVKDGDLVIVDGDAGVVIVNpdeetlaeyRE 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 235 ADAIAAARESGGATVEHDPVTTAGGRHVEVAANVGTPREAVAAAERGADGVGLFRTEFLFLDRETPPDEDEQYEALTEVC 314
Cdd:COG1080  241 RQAEYAAERAELARLRDLPAVTLDGVRVELAANIGLPEDAAAALENGAEGVGLFRTEFLFMDRDDLPTEEEQFEAYRAVA 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 315 EAFAGSRVVVRTLDIGGDKPIPYVDSDPGDNPFLGVRGIRFAPgERPELFEEHVRAILRAAA-GPaqLAVMFPLVSTVTE 393
Cdd:COG1080  321 EAMGGRPVTIRTLDIGGDKPLPYLPLPKEENPFLGLRAIRLCL-DRPELFRTQLRAILRASAhGN--LRIMFPMISSVEE 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 394 LDALLDEVSAIAAELDEAGVDYAVP-ELGAMVETPASVFLAREFADRLDFLSIGTNDLTQYVMAAARDDDRVASLHDPLH 472
Cdd:COG1080  398 LRQAKALLEEAKAELRAEGIPFDEDiPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNEKVAYLYDPLH 477

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 473 PPVLRAIARTVEAAHDGDAWVGMCGEMAGDPAHTELLVGLGFDELSMSAVTIPEVKAGVRAVDDESAAALAEAALRAETN 552
Cdd:COG1080  478 PAVLRLIKMVIDAAHKAGKPVGVCGEMAGDPLATPLLLGLGLDELSMSPSSIPAVKAIIRRLDLAEARALAEKALALDTA 557


                 ....*...
gi 491117537 553 EDVRALLD 560
Cdd:COG1080  558 EEVRALLE 565
 
Name Accession Description Interval E-value
PtsA COG1080
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ...
 6-560 0e+00

Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];


Pssm-ID: 440698 [Multi-domain]  Cd Length: 571  Bit Score: 688.35  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537   6 ISGVGVTPLLGVGTVVQYD-STVDLDESERSAAGPEAELRRFEAARETAADELARERSRTAERVGTEEAEIFDAHQQFLA 84
Cdd:COG1080    1 LKGIAASPGIAIGKAFLLReEDLEVPEYTISPEDVEAEIARLEAALAKAREELEALREKAPEDLGEEEAAIFDAHLLLLE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  85 DPQITDGVETAISEDGLTAERAVSQAFEDPIATFEA-ADGMFAERADDLRDVRDRVLRILLDRDRVDLSALPEGTVLVAE 163
Cdd:COG1080   81 DPELIEEVEELIREGRYNAEWALKEVIEELAAQFEAlDDEYLRERAADIRDVGRRVLRNLLGVEAPDLSDLPEPVILVAH 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 164 RLTPSDTAQLDPDAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRLVVDGTTGDVTVD---------PD 234
Cdd:COG1080  161 DLTPSDTAQLDPSRVAGFVTDLGGRTSHTAILARSLGIPAVVGLGDALLLVKDGDLVIVDGDAGVVIVNpdeetlaeyRE 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 235 ADAIAAARESGGATVEHDPVTTAGGRHVEVAANVGTPREAVAAAERGADGVGLFRTEFLFLDRETPPDEDEQYEALTEVC 314
Cdd:COG1080  241 RQAEYAAERAELARLRDLPAVTLDGVRVELAANIGLPEDAAAALENGAEGVGLFRTEFLFMDRDDLPTEEEQFEAYRAVA 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 315 EAFAGSRVVVRTLDIGGDKPIPYVDSDPGDNPFLGVRGIRFAPgERPELFEEHVRAILRAAA-GPaqLAVMFPLVSTVTE 393
Cdd:COG1080  321 EAMGGRPVTIRTLDIGGDKPLPYLPLPKEENPFLGLRAIRLCL-DRPELFRTQLRAILRASAhGN--LRIMFPMISSVEE 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 394 LDALLDEVSAIAAELDEAGVDYAVP-ELGAMVETPASVFLAREFADRLDFLSIGTNDLTQYVMAAARDDDRVASLHDPLH 472
Cdd:COG1080  398 LRQAKALLEEAKAELRAEGIPFDEDiPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNEKVAYLYDPLH 477

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 473 PPVLRAIARTVEAAHDGDAWVGMCGEMAGDPAHTELLVGLGFDELSMSAVTIPEVKAGVRAVDDESAAALAEAALRAETN 552
Cdd:COG1080  478 PAVLRLIKMVIDAAHKAGKPVGVCGEMAGDPLATPLLLGLGLDELSMSPSSIPAVKAIIRRLDLAEARALAEKALALDTA 557


                 ....*...
gi 491117537 553 EDVRALLD 560
Cdd:COG1080  558 EEVRALLE 565
PTS_I_fam TIGR01417
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ...
 6-560 5.19e-159

phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.


Pssm-ID: 273611 [Multi-domain]  Cd Length: 565  Bit Score: 465.42  E-value: 5.19e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537    6 ISGVGVTPLLGVGTVVQY-DSTVDLDESERSAAGPEAELRRFEAARETAADELARERSRTAERVGTEEAEIFDAHQQFLA 84
Cdd:TIGR01417   1 ISGIGVSPGIAIGKALLLkKPDLVIDRKKISASQVDQEISRFLSARAKAKEDLETIKTKAGKTFGQEKAAIFEAHILILE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537   85 DPQITDGVETAISEDGLTAERAVSQAFEDPIATFEAADG-MFAERADDLRDVRDRVLRILLDRDRVDLSALPEGTVLVAE 163
Cdd:TIGR01417  81 DPELTEEVIELIKKDHKNAEFAAHEVFEGQAKSLEEMDDeYLKERAADIRDIGNRLLGHLLGVKISDLSEIQDEVILVAE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  164 RLTPSDTAQLDPDAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRLVVDGTTGDVTVDPDADAIAAARE 243
Cdd:TIGR01417 161 DLTPSETAQLNLKYVKGFLTDAGGKTSHTAIMARSLEIPAIVGTKSVTSQVKNGDTVIIDGVKGIVIFNPSSETIDKYEA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  244 SGGATVE---------HDPVTTAGGRHVEVAANVGTPREAVAAAERGADGVGLFRTEFLFLDRETPPDEDEQYEALTEVC 314
Cdd:TIGR01417 241 KQEAVSSekaelaklkDKPAITLDGHQVELAANIGTVDDVEGAERNGGEGIGLFRTEFLYMSRDQLPTEEEQFAAYKTVL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  315 EAFAGSRVVVRTLDIGGDKPIPYVDSDPGDNPFLGVRGIRFAPgERPELFEEHVRAILRAAAgPAQLAVMFPLVSTVTEL 394
Cdd:TIGR01417 321 EAMESDAVIVRTLDIGGDKELPYLNFPKEENPFLGYRAIRLAL-EREEILRTQLRAILRASA-YGKLRIMFPMVATVEEI 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  395 DALLDEVSAIAAELDEAGVDYAVP-ELGAMVETPASVFLAREFADRLDFLSIGTNDLTQYVMAAARDDDRVASLHDPLHP 473
Cdd:TIGR01417 399 RAVKQELEEEKQELNDEGKAFDENiEVGVMIEIPSAALIADHLAKEVDFFSIGTNDLTQYTLAVDRGNDLISNLYQPYNP 478

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  474 PVLRAIARTVEAAHDGDAWVGMCGEMAGDPAHTELLVGLGFDELSMSAVTIPEVKAGVRAVDDESAAALAEAALRAETNE 553
Cdd:TIGR01417 479 AVLRLIKLVIDAAKAEGIWVGMCGEMAGDERAIPLLLGLGLRELSMSASSILRIKMIIRKLNIEECKSLAEKALAQPTTE 558


                  ....*..
gi 491117537  554 DVRALLD 560
Cdd:TIGR01417 559 EVHKLVN 565
PRK11177 PRK11177
phosphoenolpyruvate-protein phosphotransferase PtsI;
6-560 1.05e-148

phosphoenolpyruvate-protein phosphotransferase PtsI;


Pssm-ID: 183017 [Multi-domain]  Cd Length: 575  Bit Score: 439.45  E-value: 1.05e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537   6 ISGVGVTPLLGVGT--VVQYDSTVdLDESERSAAGPEAELRRFEAARETAADELARERSRTAERVGTEEAEIFDAHQQFL 83
Cdd:PRK11177   2 ISGILASPGIAFGKalLLKEDEIV-INRKKISADQVDQEVERFLSGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  84 ADPQITDGVETAISEDGLTAERAVSQAFEDPIATFEAADGMF-AERADDLRDVRDRVLRILLDRDRVDLSALPEGTVLVA 162
Cdd:PRK11177  81 EDEELEQEIIALIKDKHMTADAAAHSVIEGQAKALEELDDEYlKERAADVRDIGKRLLKNILGLKIIDLSAIQEEVILVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 163 ERLTPSDTAQLDPDAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRLVVDGTTGDVTVDPDADAIAAAR 242
Cdd:PRK11177 161 ADLTPSETAQLNLKKVLGFITDIGGRTSHTSIMARSLELPAIVGTGNITKQVKNGDYLILDAVNNQIYVNPTNEVIEELK 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 243 esggaTVEHD--------------PVTTAGGRHVEVAANVGTPREAVAAAERGADGVGLFRTEFLFLDRETPPDEDEQYE 308
Cdd:PRK11177 241 -----AVQEQyasekaelaklkdlPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFQ 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 309 ALTEVCEAFAGSRVVVRTLDIGGDKPIPYVDSDPGDNPFLGVRGIRFAPgERPELFEEHVRAILRAAAGpAQLAVMFPLV 388
Cdd:PRK11177 316 AYKAVAEAMGSQAVIVRTMDIGGDKELPYMNLPKEENPFLGWRAIRIAM-DRKEILHDQLRAILRASAF-GKLRIMFPMI 393

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 389 STVTELDALLDEVSAIAAELDEAGVDY-AVPELGAMVETPASVFLAREFADRLDFLSIGTNDLTQYVMAAARDDDRVASL 467
Cdd:PRK11177 394 ISVEEVRELKAEIEILKQELRDEGKAFdESIEIGVMVETPAAAVIARHLAKEVDFFSIGTNDLTQYTLAVDRGNELISHL 473

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 468 HDPLHPPVLRAIARTVEAAHDGDAWVGMCGEMAGDPAHTELLVGLGFDELSMSAVTIPEVKAGVRAVDDESAAALAEAAL 547
Cdd:PRK11177 474 YNPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKALAEQAL 553

                        570
                 ....*....|...
gi 491117537 548 RAETNEDVRALLD 560
Cdd:PRK11177 554 AQPTADELMTLVN 566
PEP-utilizers_C pfam02896
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ...
 245-535 6.83e-113

PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.


Pssm-ID: 397163 [Multi-domain]  Cd Length: 292  Bit Score: 337.74  E-value: 6.83e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  245 GGATVEHDPVTTAGGRHVEVAANVGTPREAVAAAERGADGVGLFRTEFLFLDRETPPDEDEQYEALTEVCEAFAGSRVVV 324
Cdd:pfam02896   3 ELGKLKDLPAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDELPTEDEQFEAYKGVLEAMNGRPVTV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  325 RTLDIGGDKPIPYVDSDPGDNPFLGVRGIRFAPgERPELFEEHVRAILRAAAGpAQLAVMFPLVSTVTELDALLDEVSAI 404
Cdd:pfam02896  83 RTLDIGGDKELPYLEEPEEMNPFLGWRGIRIGL-DRPELFRTQLRAILRASAF-GNLRIMFPMVASVEELREAKAIIEEV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  405 AAELDEAGVDYAVPELGAMVETPASVFLAREFADRLDFLSIGTNDLTQYVMAAARDDDRVASLHDPLHPPVLRAIARTVE 484
Cdd:pfam02896 161 KEELDAEVGFDKDIKVGIMIEVPSAALLADQLAKEVDFFSIGTNDLTQYTLAVDRDNERVAYLYDPLHPAVLRLIKEVIR 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 491117537  485 AAHDGDAWVGMCGEMAGDPAHTELLVGLGFDELSMSAVTIPEVKAGVRAVD 535
Cdd:pfam02896 241 AAHRHGKWVGICGEMAGDPSAVPLLVGLGLDEFSMSPDSVPRARALLAQID 291
 
Name Accession Description Interval E-value
PtsA COG1080
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ...
 6-560 0e+00

Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];


Pssm-ID: 440698 [Multi-domain]  Cd Length: 571  Bit Score: 688.35  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537   6 ISGVGVTPLLGVGTVVQYD-STVDLDESERSAAGPEAELRRFEAARETAADELARERSRTAERVGTEEAEIFDAHQQFLA 84
Cdd:COG1080    1 LKGIAASPGIAIGKAFLLReEDLEVPEYTISPEDVEAEIARLEAALAKAREELEALREKAPEDLGEEEAAIFDAHLLLLE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  85 DPQITDGVETAISEDGLTAERAVSQAFEDPIATFEA-ADGMFAERADDLRDVRDRVLRILLDRDRVDLSALPEGTVLVAE 163
Cdd:COG1080   81 DPELIEEVEELIREGRYNAEWALKEVIEELAAQFEAlDDEYLRERAADIRDVGRRVLRNLLGVEAPDLSDLPEPVILVAH 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 164 RLTPSDTAQLDPDAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRLVVDGTTGDVTVD---------PD 234
Cdd:COG1080  161 DLTPSDTAQLDPSRVAGFVTDLGGRTSHTAILARSLGIPAVVGLGDALLLVKDGDLVIVDGDAGVVIVNpdeetlaeyRE 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 235 ADAIAAARESGGATVEHDPVTTAGGRHVEVAANVGTPREAVAAAERGADGVGLFRTEFLFLDRETPPDEDEQYEALTEVC 314
Cdd:COG1080  241 RQAEYAAERAELARLRDLPAVTLDGVRVELAANIGLPEDAAAALENGAEGVGLFRTEFLFMDRDDLPTEEEQFEAYRAVA 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 315 EAFAGSRVVVRTLDIGGDKPIPYVDSDPGDNPFLGVRGIRFAPgERPELFEEHVRAILRAAA-GPaqLAVMFPLVSTVTE 393
Cdd:COG1080  321 EAMGGRPVTIRTLDIGGDKPLPYLPLPKEENPFLGLRAIRLCL-DRPELFRTQLRAILRASAhGN--LRIMFPMISSVEE 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 394 LDALLDEVSAIAAELDEAGVDYAVP-ELGAMVETPASVFLAREFADRLDFLSIGTNDLTQYVMAAARDDDRVASLHDPLH 472
Cdd:COG1080  398 LRQAKALLEEAKAELRAEGIPFDEDiPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNEKVAYLYDPLH 477

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 473 PPVLRAIARTVEAAHDGDAWVGMCGEMAGDPAHTELLVGLGFDELSMSAVTIPEVKAGVRAVDDESAAALAEAALRAETN 552
Cdd:COG1080  478 PAVLRLIKMVIDAAHKAGKPVGVCGEMAGDPLATPLLLGLGLDELSMSPSSIPAVKAIIRRLDLAEARALAEKALALDTA 557


                 ....*...
gi 491117537 553 EDVRALLD 560
Cdd:COG1080  558 EEVRALLE 565
PTS_I_fam TIGR01417
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ...
 6-560 5.19e-159

phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.


Pssm-ID: 273611 [Multi-domain]  Cd Length: 565  Bit Score: 465.42  E-value: 5.19e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537    6 ISGVGVTPLLGVGTVVQY-DSTVDLDESERSAAGPEAELRRFEAARETAADELARERSRTAERVGTEEAEIFDAHQQFLA 84
Cdd:TIGR01417   1 ISGIGVSPGIAIGKALLLkKPDLVIDRKKISASQVDQEISRFLSARAKAKEDLETIKTKAGKTFGQEKAAIFEAHILILE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537   85 DPQITDGVETAISEDGLTAERAVSQAFEDPIATFEAADG-MFAERADDLRDVRDRVLRILLDRDRVDLSALPEGTVLVAE 163
Cdd:TIGR01417  81 DPELTEEVIELIKKDHKNAEFAAHEVFEGQAKSLEEMDDeYLKERAADIRDIGNRLLGHLLGVKISDLSEIQDEVILVAE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  164 RLTPSDTAQLDPDAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRLVVDGTTGDVTVDPDADAIAAARE 243
Cdd:TIGR01417 161 DLTPSETAQLNLKYVKGFLTDAGGKTSHTAIMARSLEIPAIVGTKSVTSQVKNGDTVIIDGVKGIVIFNPSSETIDKYEA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  244 SGGATVE---------HDPVTTAGGRHVEVAANVGTPREAVAAAERGADGVGLFRTEFLFLDRETPPDEDEQYEALTEVC 314
Cdd:TIGR01417 241 KQEAVSSekaelaklkDKPAITLDGHQVELAANIGTVDDVEGAERNGGEGIGLFRTEFLYMSRDQLPTEEEQFAAYKTVL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  315 EAFAGSRVVVRTLDIGGDKPIPYVDSDPGDNPFLGVRGIRFAPgERPELFEEHVRAILRAAAgPAQLAVMFPLVSTVTEL 394
Cdd:TIGR01417 321 EAMESDAVIVRTLDIGGDKELPYLNFPKEENPFLGYRAIRLAL-EREEILRTQLRAILRASA-YGKLRIMFPMVATVEEI 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  395 DALLDEVSAIAAELDEAGVDYAVP-ELGAMVETPASVFLAREFADRLDFLSIGTNDLTQYVMAAARDDDRVASLHDPLHP 473
Cdd:TIGR01417 399 RAVKQELEEEKQELNDEGKAFDENiEVGVMIEIPSAALIADHLAKEVDFFSIGTNDLTQYTLAVDRGNDLISNLYQPYNP 478

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  474 PVLRAIARTVEAAHDGDAWVGMCGEMAGDPAHTELLVGLGFDELSMSAVTIPEVKAGVRAVDDESAAALAEAALRAETNE 553
Cdd:TIGR01417 479 AVLRLIKLVIDAAKAEGIWVGMCGEMAGDERAIPLLLGLGLRELSMSASSILRIKMIIRKLNIEECKSLAEKALAQPTTE 558


                  ....*..
gi 491117537  554 DVRALLD 560
Cdd:TIGR01417 559 EVHKLVN 565
PRK11177 PRK11177
phosphoenolpyruvate-protein phosphotransferase PtsI;
6-560 1.05e-148

phosphoenolpyruvate-protein phosphotransferase PtsI;


Pssm-ID: 183017 [Multi-domain]  Cd Length: 575  Bit Score: 439.45  E-value: 1.05e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537   6 ISGVGVTPLLGVGT--VVQYDSTVdLDESERSAAGPEAELRRFEAARETAADELARERSRTAERVGTEEAEIFDAHQQFL 83
Cdd:PRK11177   2 ISGILASPGIAFGKalLLKEDEIV-INRKKISADQVDQEVERFLSGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  84 ADPQITDGVETAISEDGLTAERAVSQAFEDPIATFEAADGMF-AERADDLRDVRDRVLRILLDRDRVDLSALPEGTVLVA 162
Cdd:PRK11177  81 EDEELEQEIIALIKDKHMTADAAAHSVIEGQAKALEELDDEYlKERAADVRDIGKRLLKNILGLKIIDLSAIQEEVILVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 163 ERLTPSDTAQLDPDAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRLVVDGTTGDVTVDPDADAIAAAR 242
Cdd:PRK11177 161 ADLTPSETAQLNLKKVLGFITDIGGRTSHTSIMARSLELPAIVGTGNITKQVKNGDYLILDAVNNQIYVNPTNEVIEELK 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 243 esggaTVEHD--------------PVTTAGGRHVEVAANVGTPREAVAAAERGADGVGLFRTEFLFLDRETPPDEDEQYE 308
Cdd:PRK11177 241 -----AVQEQyasekaelaklkdlPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFQ 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 309 ALTEVCEAFAGSRVVVRTLDIGGDKPIPYVDSDPGDNPFLGVRGIRFAPgERPELFEEHVRAILRAAAGpAQLAVMFPLV 388
Cdd:PRK11177 316 AYKAVAEAMGSQAVIVRTMDIGGDKELPYMNLPKEENPFLGWRAIRIAM-DRKEILHDQLRAILRASAF-GKLRIMFPMI 393

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 389 STVTELDALLDEVSAIAAELDEAGVDY-AVPELGAMVETPASVFLAREFADRLDFLSIGTNDLTQYVMAAARDDDRVASL 467
Cdd:PRK11177 394 ISVEEVRELKAEIEILKQELRDEGKAFdESIEIGVMVETPAAAVIARHLAKEVDFFSIGTNDLTQYTLAVDRGNELISHL 473

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 468 HDPLHPPVLRAIARTVEAAHDGDAWVGMCGEMAGDPAHTELLVGLGFDELSMSAVTIPEVKAGVRAVDDESAAALAEAAL 547
Cdd:PRK11177 474 YNPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKALAEQAL 553

                        570
                 ....*....|...
gi 491117537 548 RAETNEDVRALLD 560
Cdd:PRK11177 554 AQPTADELMTLVN 566
PEP-utilizers_C pfam02896
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ...
 245-535 6.83e-113

PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.


Pssm-ID: 397163 [Multi-domain]  Cd Length: 292  Bit Score: 337.74  E-value: 6.83e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  245 GGATVEHDPVTTAGGRHVEVAANVGTPREAVAAAERGADGVGLFRTEFLFLDRETPPDEDEQYEALTEVCEAFAGSRVVV 324
Cdd:pfam02896   3 ELGKLKDLPAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDELPTEDEQFEAYKGVLEAMNGRPVTV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  325 RTLDIGGDKPIPYVDSDPGDNPFLGVRGIRFAPgERPELFEEHVRAILRAAAGpAQLAVMFPLVSTVTELDALLDEVSAI 404
Cdd:pfam02896  83 RTLDIGGDKELPYLEEPEEMNPFLGWRGIRIGL-DRPELFRTQLRAILRASAF-GNLRIMFPMVASVEELREAKAIIEEV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  405 AAELDEAGVDYAVPELGAMVETPASVFLAREFADRLDFLSIGTNDLTQYVMAAARDDDRVASLHDPLHPPVLRAIARTVE 484
Cdd:pfam02896 161 KEELDAEVGFDKDIKVGIMIEVPSAALLADQLAKEVDFFSIGTNDLTQYTLAVDRDNERVAYLYDPLHPAVLRLIKEVIR 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 491117537  485 AAHDGDAWVGMCGEMAGDPAHTELLVGLGFDELSMSAVTIPEVKAGVRAVD 535
Cdd:pfam02896 241 AAHRHGKWVGICGEMAGDPSAVPLLVGLGLDEFSMSPDSVPRARALLAQID 291
PRK11061 PRK11061
phosphoenolpyruvate--protein phosphotransferase;
5-558 6.10e-109

phosphoenolpyruvate--protein phosphotransferase;


Pssm-ID: 182937 [Multi-domain]  Cd Length: 748  Bit Score: 342.36  E-value: 6.10e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537   5 RISGVGVTPLLGVGTVVQYDSTVDLDE-SERSAAGPEAELRRFEAARETAADELARERSRTAERVGTEEAEIFDAHQQFL 83
Cdd:PRK11061 170 RIRALPASPGVAIAEGWQDATQPLLEQvYPASTLDPALERERLTGALEEAANEFRRYSKRFAAGAQKETAAIFDLYSHLL 249

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  84 ADPQITDGVETAIsEDGLTAERAVSQAFEDPIATFEA-ADGMFAERADDLRDVRDRVLrILLDRDRVDLSALPEGTVLVA 162
Cdd:PRK11061 250 NDPRLRRELFAEV-DKGSVAEWAVKQVIEKFAEQFAAlSDNYLRERAGDLRALGQRLL-FHLDDSEQGPNAWPERFILVA 327

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 163 ERLTPSDTAQLDPDAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDvLDLADGTRLVVDGTTGDVTVDPDADAIAAAR 242
Cdd:PRK11061 328 DELTATLLAELPQDRLAGVVVRDGAANSHAAILVRALGIPTVMGADIQ-PSLLHQRLLIVDGYRGELLVDPEPVLLQEYQ 406

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 243 E------SGGATVEHD---PVTTAGGRHVEVAANVGTPREAVAAAERGADGVGLFRTEFLFLDRETPPDEDEQYEALTEV 313
Cdd:PRK11061 407 RliseeiELSRLAEDDvnlPAQLKSGERIKVMLNAGLSAEHEEKLGSRVDGVGLYRTEIPFMLQSGFPSEEEQVAQYQGM 486

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 314 CEAFAGSRVVVRTLDIGGDKPIPYVDSDPgDNPFLGVRGIRFAPgERPELFEEHVRAILRAAAGPAQLAVMFPLVSTVTE 393
Cdd:PRK11061 487 LQMFPDKPVTLRTLDIGADKQLPYMPISE-ENPCLGWRGIRITL-DQPEIFLIQVRAMLRANAATGNLSILLPMVTSIDE 564

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 394 LD---ALLDEvsAIAAELDEAGVDYAVPELGAMVETPASVFLAREFADRLDFLSIGTNDLTQYVMAAARDDDRVASLHDP 470
Cdd:PRK11061 565 VDearRLIDR--AGREVEEMLGYEIPKPRIGIMIEVPSMVFMLPHLASRVDFISVGTNDLTQYLLAVDRNNTRVASLYDS 642

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 471 LHPPVLRAIARTVEAAHDGDAWVGMCGEMAGDPAHTELLVGLGFDELSMSAVTIPEVKAGVRAVDDESAAALAEAALRAE 550
Cdd:PRK11061 643 LHPAMLRALKMIADEAEQHGLPVSLCGEMAGDPMGALLLIGLGYRHLSMNGRSVARVKYLLRHIDLAEAENLAQRSLEAQ 722


                 ....*...
gi 491117537 551 TNEDVRAL 558
Cdd:PRK11061 723 LATEVRHQ 730
PRK06464 PRK06464
phosphoenolpyruvate synthase; Validated
 141-521 1.16e-63

phosphoenolpyruvate synthase; Validated


Pssm-ID: 235809 [Multi-domain]  Cd Length: 795  Bit Score: 222.70  E-value: 1.16e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 141 RILLDRDrvDLSALPEGTVLVAERltpsdTaqlDPDAV------AGFVTVEGGRTSHAAIMARSLAIPAVVGVG--TDVL 212
Cdd:PRK06464 372 RVILDIS--EMDKVQPGDVLVTDM-----T---DPDWEpvmkraSAIVTNRGGRTCHAAIIARELGIPAVVGTGnaTEVL 441

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 213 dlADGTRLVV---DGTTGDVtvdpdadaiaaarESG--GATVEHDPVTTAGGRHVEVAANVGTPREAVAAAERGADGVGL 287
Cdd:PRK06464 442 --KDGQEVTVscaEGDTGYV-------------YEGllEFEVEEVSLEEMPETPTKIMMNVGNPERAFDFAALPNDGVGL 506

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 288 FRTEFLFL------------DRETPPDEDEQYEALTE-------------------VCEAFAGSRVVVRTLD-------- 328
Cdd:PRK06464 507 ARLEFIINnmigvhplalleFDQQDADLKAEIEELTAgyaspeefyvdklaegiatVAAAFYPKPVIVRLSDfksneyan 586

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 329 -IGGDKPIPYvdsdpGDNPFLGVRGIR--FAPGERpELFEEHVRAI--LRAAAGPAQLAVMFPLVSTVteldallDEVSA 403
Cdd:PRK06464 587 lIGGERYEPE-----EENPMLGFRGASryLSESFR-EAFALECEAIkrVREEMGLTNVEVMIPFVRTV-------EEAEK 653

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 404 IAAELDEAGVDYAVP--ELGAMVETPASVFLAREFADRLDFLSIGTNDLTQYVMAAARDDDRVASLHDPLHPPVLRAIAR 481
Cdd:PRK06464 654 VIELLAENGLKRGENglKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGLVAHLFDERNPAVKKLISM 733

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|.
gi 491117537 482 TVEAAHDGDAWVGMCGEMAGD-PAHTELLVGLGFDelSMSA 521
Cdd:PRK06464 734 AIKAAKKAGKYVGICGQAPSDhPDFAEWLVEEGID--SISL 772
PEP-utilizers_N pfam05524
PEP-utilizing enzyme, N-terminal;
7-128 1.57e-26

PEP-utilizing enzyme, N-terminal;


Pssm-ID: 461671 [Multi-domain]  Cd Length: 125  Bit Score: 104.23  E-value: 1.57e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537    7 SGVGVTPLLGVGTVVQY--DSTVDLDESERSAAGPEAELRRFEAARETAADELARERSRTAERVGTEEAEIFDAHQQFLA 84
Cdd:pfam05524   1 KGIGASPGIAIGKAVVLeePELEVPDEREVPADDVEAEIARLEAALEAAREELEALAERAAGELGEEEAAIFEAHLMMLE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 491117537   85 DPQITDGVETAISEDGLTAERAVSQAFEDPIATFEAADG-MFAER 128
Cdd:pfam05524  81 DPELLEEVEELIREGGLNAEAAVKEVVDEFAAMFEAMDDpYLRER 125
PEP-utilizers pfam00391
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain ...
 153-227 8.64e-26

PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.


Pssm-ID: 459796 [Multi-domain]  Cd Length: 73  Bit Score: 100.56  E-value: 8.64e-26
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 491117537  153 ALPEGTVLVAERLTPSDTAQLDpdAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRLVVDGTTG 227
Cdd:pfam00391   1 KLPEGVILVAPDTTPSDTAGLD--KAAGIVTERGGMTSHAAIVARELGIPAVVGVGDATILLKEGDLVTVDGSTG 73
PRK11377 PRK11377
dihydroxyacetone kinase subunit M; Provisional
 18-227 5.03e-20

dihydroxyacetone kinase subunit M; Provisional


Pssm-ID: 183108 [Multi-domain]  Cd Length: 473  Bit Score: 92.89  E-value: 5.03e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  18 GTVVQYdSTVDLDESERSAAGPEAELRRFEAARETAADELARERSRTAERVGTEEAEIFDAHQQFLADPQITDGVETAIS 97
Cdd:PRK11377 259 GKAFYY-QPVLCTVQAKSTLTVEEEQERLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSGHHTLLDDPELLAAASERLQ 337

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537  98 EDGLTAERAVSQAFEDPIATFEAADGMFAE-RADDLRDVRDRVLRILLDRDRVdLSALPEGTVLVAERLTPSDTAQLDPD 176
Cdd:PRK11377 338 HEHCTAEYAWQQVLKELSQQYQQLDDEYLQaRYIDVDDLLHRTLVHLTQTKEE-LPQFNSPTILLAENIYPSTVLQLDPA 416

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 491117537 177 AVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRLVVDGTTG 227
Cdd:PRK11377 417 VVKGICLSAGSPLSHSAIIARELGIGWICQQGEKLYAIQPEETLTLDVKTQ 467
PpsA COG0574
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ...
 141-229 3.49e-18

Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis


Pssm-ID: 440339 [Multi-domain]  Cd Length: 455  Bit Score: 87.19  E-value: 3.49e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 141 RILLDRDRVDLSALPEGTVLVAERLTPSDTAQLDpdAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRL 220
Cdd:COG0574  368 KVVFIADEAELARFQEGVILVRDETDPDDVPGMK--AAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATRVLKDGDEI 445


                 ....*....
gi 491117537 221 VVDGTTGDV 229
Cdd:COG0574  446 TVDGTTGEV 454
PRK08296 PRK08296
hypothetical protein; Provisional
 141-231 1.78e-11

hypothetical protein; Provisional


Pssm-ID: 181362  Cd Length: 603  Bit Score: 66.60  E-value: 1.78e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 141 RILLDRDrvDLSALPEGTVLVAERLTPSDTAQLDpdAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRL 220
Cdd:PRK08296 515 RVIRSAD--ELSEVQEGEILVCPVTSPSWAPIFA--KIKATVTDIGGVMSHAAIVCREYGLPAVVGTGNATKRIKTGQRL 590

                         90
                 ....*....|.
gi 491117537 221 VVDGTTGDVTV 231
Cdd:PRK08296 591 RVDGTKGVVTI 601
PykA2 COG3848
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
150-229 1.03e-09

Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];


Pssm-ID: 443058  Cd Length: 321  Bit Score: 59.91  E-value: 1.03e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 150 DLSALPEGTVLVaerlTPSDTAQLDPDA--VAGFVTVEGGRTSHAAIMARSLAIPAVVGVgTDVLD-LADGTRLVVDGTT 226
Cdd:COG3848  236 ALEKFEEGDILV----VPSTDAEFVPAIekAAGIITEEGGLTSHAAIVGLELGIPVIVGA-EGATEiLKDGQVVTVDAER 310


                 ...
gi 491117537 227 GDV 229
Cdd:COG3848  311 GVV 313
PRK05878 PRK05878
pyruvate phosphate dikinase; Provisional
 150-229 4.91e-09

pyruvate phosphate dikinase; Provisional


Pssm-ID: 235635 [Multi-domain]  Cd Length: 530  Bit Score: 58.99  E-value: 4.91e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 150 DLSALPEGTVLVAERLTPSDTAQLDpdAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRLVVDGTTGDV 229
Cdd:PRK05878 374 DAADRGEPVILVRDHTRPDDVHGML--AAQGIVTEVGGATSHAAVVSRELGRVAVVGCGAGVAAALAGKEITVDGYEGEV 451
PRK06241 PRK06241
phosphoenolpyruvate synthase; Validated
 154-231 1.68e-06

phosphoenolpyruvate synthase; Validated


Pssm-ID: 235751 [Multi-domain]  Cd Length: 871  Bit Score: 51.04  E-value: 1.68e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 491117537 154 LPEGTVLVAERLTPSDTAqLDPdAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVgTDVLDL-ADGTRLVVDGTTGDVTV 231
Cdd:PRK06241 793 LEKGDILVTAFTDPGWTP-LFV-SIKGLVTEVGGLMTHGAVIAREYGIPAVVGV-ENATKLiKDGQRIRVDGTEGYVEI 868
PRK06354 PRK06354
pyruvate kinase; Provisional
 150-229 3.60e-06

pyruvate kinase; Provisional


Pssm-ID: 235784 [Multi-domain]  Cd Length: 590  Bit Score: 49.92  E-value: 3.60e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 150 DLSALPEGTVLVAERlTPSDTAQLDPDAvAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRLVVDGTTGDV 229
Cdd:PRK06354 505 EVAKVNEGDILVTPS-TDADMIPAIEKA-AAIITEEGGLTSHAAVVGLRLGIPVIVGVKNATSLIKDGQIITVDAARGVV 582
PRK05849 PRK05849
hypothetical protein; Provisional
 178-208 9.59e-05

hypothetical protein; Provisional


Pssm-ID: 235623 [Multi-domain]  Cd Length: 783  Bit Score: 45.36  E-value: 9.59e-05
                         10        20        30
                 ....*....|....*....|....*....|.
gi 491117537 178 VAGFVTVEGGRTSHAAIMARSLAIPAVVGVG 208
Cdd:PRK05849 728 IAGLITCYGGANSHMAIRAAELGLPAVIGVG 758
CitE COG2301
Citrate lyase beta subunit [Carbohydrate transport and metabolism];
362-487 3.17e-04

Citrate lyase beta subunit [Carbohydrate transport and metabolism];


Pssm-ID: 441876  Cd Length: 288  Bit Score: 42.83  E-value: 3.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491117537 362 ELFEEHVRAIlrAAAGPAqlAVMFPLVSTVteldallDEVSAIAAELDEAGVDYAVPELGAMVETPASVFLAREFA---D 438
Cdd:COG2301   75 PWGLDDLAAL--VGAGLD--GIVLPKVESA-------EDVRALAALLTELEAEGGSIPLMALIETARGLLNAAEIAaasP 143

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 491117537 439 RLDFLSIGTNDLTQyVMAAARDDDRvaslhdplhPPVLRAIARTVEAAH 487
Cdd:COG2301  144 RVEALVFGAEDLAA-DLGARRTRDG---------DELLYARSRIVLAAR 182
PRK05865 PRK05865
sugar epimerase family protein;
154-231 4.79e-04

sugar epimerase family protein;


Pssm-ID: 235630 [Multi-domain]  Cd Length: 854  Bit Score: 43.11  E-value: 4.79e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491117537 154 LPEGTVLVAERLTPSDTAQLDpdAVAGFVTVEGGRTSHAAIMARSLAIPAVVGVGTDVLDLADGTRLVVDGTTGDVTV 231
Cdd:PRK05865 761 LQPGEILVAEVTDVGYTAAFC--YAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGATGEIHV 836
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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