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Conserved domains on  [gi|496252754|ref|WP_008966139|]
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tetratricopeptide repeat protein [Bradyrhizobium sp. STM 3809]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 59-171 3.75e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.70  E-value: 3.75e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  59 AAYRTAYTSIYDRGDYATAIQQLKALNR--EDVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLE 136
Cdd:COG3914   79 ALLELAALLLQALGRYEEALALYRRALAlnPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRR 158

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 496252754 137 QGNREQAKYHLDKVAQLAGTNSPEYRSLADALEKQ 171
Cdd:COG3914  159 LGRLEEAIAALRRALELDPDNAEALNNLGNALQDL 193
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 59-171 3.75e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.70  E-value: 3.75e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  59 AAYRTAYTSIYDRGDYATAIQQLKALNR--EDVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLE 136
Cdd:COG3914   79 ALLELAALLLQALGRYEEALALYRRALAlnPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRR 158

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 496252754 137 QGNREQAKYHLDKVAQLAGTNSPEYRSLADALEKQ 171
Cdd:COG3914  159 LGRLEEAIAALRRALELDPDNAEALNNLGNALQDL 193
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 104-160 6.87e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 41.85  E-value: 6.87e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 496252754 104 GNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYHLDKVAQLAGTNSPE 160
Cdd:cd24142   14 GNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYE 70
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 71-171 3.68e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 3.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754   71 RGDYATAIQQLKA---LNREDVADVANLIGYSYRKlGNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYHL 147
Cdd:TIGR02917 478 KGDLAKAREAFEKalsIEPDFFPAAANLARIDIQE-GNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWL 556

                          90       100
                  ....*....|....*....|....
gi 496252754  148 DKVAQLAGTNSPEYRSLADALEKQ 171
Cdd:TIGR02917 557 EKAAELNPQEIEPALALAQYYLGK 580
TPR_12 pfam13424
Tetratricopeptide repeat;
88-154 9.58e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.60  E-value: 9.58e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496252754   88 DVADVANLIGYSYRKLGNYQASKQYYEQALA--------DDPNHVRTWQYYGLWQLEQGNREQAKYHLDKVAQLA 154
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEiarrllgpDHPLTATTLLNLGRLYLELGRYEEALELLERALALA 75
ycf3 CHL00033
photosystem I assembly protein Ycf3
 71-160 6.27e-03

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 35.75  E-value: 6.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  71 RGDYATAIQQ-LKALNRE-DVADVANL---IGYSYRKLGNYQASKQYYEQALADDPNHVRTW-------QYYGLWQLEQG 138
Cdd:CHL00033  48 EGEYAEALQNyYEAMRLEiDPYDRSYIlynIGLIHTSNGEHTKALEYYFQALERNPFLPQALnnmavicHYRGEQAIEQG 127

                         90       100
                 ....*....|....*....|....*....
gi 496252754 139 NREQAKYHLDKVA-------QLAGTNSPE 160
Cdd:CHL00033 128 DSEIAEAWFDQAAeywkqaiALAPGNYIE 156
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 59-171 3.75e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.70  E-value: 3.75e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  59 AAYRTAYTSIYDRGDYATAIQQLKALNR--EDVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLE 136
Cdd:COG3914   79 ALLELAALLLQALGRYEEALALYRRALAlnPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRR 158

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 496252754 137 QGNREQAKYHLDKVAQLAGTNSPEYRSLADALEKQ 171
Cdd:COG3914  159 LGRLEEAIAALRRALELDPDNAEALNNLGNALQDL 193
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 53-171 1.90e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.12  E-value: 1.90e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  53 EDPKFLAAYRTAYTSIYDRGDYATAIQQLKAL--NREDVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYY 130
Cdd:COG2956  105 LDPDDAEALRLLAEIYEQEGDWEKAIEVLERLlkLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLL 184

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 496252754 131 GLWQLEQGNREQAKYHLDKVAQLAGTNSPEYRSLADALEKQ 171
Cdd:COG2956  185 AELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 54-165 9.07e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 53.84  E-value: 9.07e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  54 DPKFLAAYRTAYTSIYDRGDYATAIQQL-KALNRE-DVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYG 131
Cdd:COG3914  108 NPDNAEALFNLGNLLLALGRLEEALAALrRALALNpDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLG 187

                         90       100       110
                 ....*....|....*....|....*....|....
gi 496252754 132 LWQLEQGNREQAKYHLDKVAQLAGTNsPEYRSLA 165
Cdd:COG3914  188 NALQDLGRLEEAIAAYRRALELDPDN-ADAHSNL 220
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
54-171 1.01e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.09  E-value: 1.01e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  54 DPKFLAAYRTAYTSIYDRGDYATAIQQL-KALNRE-DVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYG 131
Cdd:COG0457    4 DPDDAEAYNNLGLAYRRLGRYEEAIEDYeKALELDpDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLG 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 496252754 132 LWQLEQGNREQAKYHLDKVAQLAGTNSPEYRSLADALEKQ 171
Cdd:COG0457   84 LALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLEL 123
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 69-170 3.40e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 49.62  E-value: 3.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  69 YDRGDYATAIQQL-KALNRE-DVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYH 146
Cdd:COG4235   28 LRLGRYDEALAAYeKALRLDpDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAA 107

                         90       100
                 ....*....|....*....|....
gi 496252754 147 LDKVAQLAGTNSPeYRSLADALEK 170
Cdd:COG4235  108 WQKLLALLPADAP-ARLLEASIAE 130
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 75-171 9.00e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 50.76  E-value: 9.00e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  75 ATAIQQLKALNREDVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYHLDKVAQLA 154
Cdd:COG3914   63 AAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALN 142

                         90
                 ....*....|....*..
gi 496252754 155 GTNSPEYRSLADALEKQ 171
Cdd:COG3914  143 PDFAEAYLNLGEALRRL 159
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 69-171 2.30e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.88  E-value: 2.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  69 YDRGDYATAIQQLKALNRED--VADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYH 146
Cdd:COG4783   15 LLAGDYDEAEALLEKALELDpdNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALAL 94

                         90       100
                 ....*....|....*....|....*
gi 496252754 147 LDKVAQLAGTNSPEYRSLADALEKQ 171
Cdd:COG4783   95 LEKALKLDPEHPEAYLRLARAYRAL 119
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
69-171 2.53e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.85  E-value: 2.53e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  69 YDRGDYATAIQQL-KALNRE-DVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYH 146
Cdd:COG0457   53 LRLGRYEEALADYeQALELDpDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEA 132

                         90       100
                 ....*....|....*....|....*
gi 496252754 147 LDKVAQLAGTNSPEYRSLADALEKQ 171
Cdd:COG0457  133 YERALELDPDDADALYNLGIALEKL 157
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 58-171 1.35e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.11  E-value: 1.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  58 LAAYRTAYTSIYDRGDYATAIQQLKALNREDVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQ 137
Cdd:COG5010   22 TLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRS 101

                         90       100       110
                 ....*....|....*....|....*....|....
gi 496252754 138 GNREQAKYHLDKVAQLAGTNSPEYRSLADALEKQ 171
Cdd:COG5010  102 GDKDEAKEYYEKALALSPDNPNAYSNLAALLLSL 135
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 69-152 2.13e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.60  E-value: 2.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  69 YDRGDYATAIQQLKALNRED-----VADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYY---GLWQLEQGNR 140
Cdd:COG1729    4 LKAGDYDEAIAAFKAFLKRYpnsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALlklGLSYLELGDY 83

                         90
                 ....*....|..
gi 496252754 141 EQAKYHLDKVAQ 152
Cdd:COG1729   84 DKARATLEELIK 95
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
54-171 3.37e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.77  E-value: 3.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  54 DPKFLAAYRTAYTSIYDRGDYATAIQQL-KALNRE-DVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYG 131
Cdd:COG0457   72 DPDDAEALNNLGLALQALGRYEEALEDYdKALELDpDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLG 151

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 496252754 132 LWQLEQGNREQAKYHLDKVAQLAGTNSPEYRSLADALEKQ 171
Cdd:COG0457  152 IALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALA 191
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 69-173 5.26e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.11  E-value: 5.26e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  69 YDRGDYATAIQQLKALNREDVADVANLI--GYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYH 146
Cdd:COG2956  155 LEQGDYDEAIEALEKALKLDPDCARALLllAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALEL 234

                         90       100
                 ....*....|....*....|....*..
gi 496252754 147 LDKVAQLAgTNSPEYRSLADALEKQPG 173
Cdd:COG2956  235 LRKALELD-PSDDLLLALADLLERKEG 260
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 53-171 5.79e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.11  E-value: 5.79e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  53 EDPKFLAAYRTAYTSIYDRGDYATAIQQLKAL--NREDVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYY 130
Cdd:COG2956   37 LDPETVEAHLALGNLYRRRGEYDRAIRIHQKLleRDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLL 116

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 496252754 131 GLWQLEQGNREQAKYHLDKVAQLAGTNSPEYRSLADALEKQ 171
Cdd:COG2956  117 AEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ 157
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 77-171 7.46e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.46  E-value: 7.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  77 AIQQLKALNREDVADVAN--LIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYHLDKVAQLA 154
Cdd:COG4235    2 AIARLRQALAANPNDAEGwlLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                         90
                 ....*....|....*..
gi 496252754 155 GTNSPEYRSLADALEKQ 171
Cdd:COG4235   82 PDNPEALYLLGLAAFQQ 98
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 53-157 8.87e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.26  E-value: 8.87e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  53 EDPKFLAAYRTAYTSIYDRGDYATAIQQLKALNREDVADVA--NLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYY 130
Cdd:COG4783   33 LDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEarLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRL 112

                         90       100
                 ....*....|....*....|....*..
gi 496252754 131 GLWQLEQGNREQAKYHLDKVAQLAGTN 157
Cdd:COG4783  113 ARAYRALGRPDEAIAALEKALELDPDD 139
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
69-154 9.11e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.46  E-value: 9.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  69 YDRGDYATAIQQL-KALNRE-DVADVANLIGYSYRKLGNYQASKQYyEQALADDPNHVRTWQYYGLWQLEQGNREQAKYH 146
Cdd:COG3063    3 LKLGDLEEAEEYYeKALELDpDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAY 81


                 ....*...
gi 496252754 147 LDKVAQLA 154
Cdd:COG3063   82 LERALELD 89
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
100-171 2.04e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.31  E-value: 2.04e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 496252754 100 YRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKyHLDKVAQLAGTNSPEYRSLADALEKQ 171
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLEL 72
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 54-154 5.94e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.67  E-value: 5.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  54 DPKFLAAYRTAYTSIYDRGDYATAIQQL-KALNRE-DVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYG 131
Cdd:COG3914  142 NPDFAEAYLNLGEALRRLGRLEEAIAALrRALELDpDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLL 221

                         90       100
                 ....*....|....*....|...
gi 496252754 132 LWQLEQGNREQAKYHLDKVAQLA 154
Cdd:COG3914  222 FALRQACDWEVYDRFEELLAALA 244
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 104-160 6.87e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 41.85  E-value: 6.87e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 496252754 104 GNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYHLDKVAQLAGTNSPE 160
Cdd:cd24142   14 GNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYE 70
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 90-171 1.01e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.56  E-value: 1.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  90 ADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYHLDKVAQLAGTNSPEYRSLADALE 169
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83


                 ..
gi 496252754 170 KQ 171
Cdd:COG4783   84 KA 85
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 15-154 2.14e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.94  E-value: 2.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  15 AMAVASGPLLLSKAYAAGSETPSAPPPDKKKKDKSSSIEDPKFLAAYRTAYTSIYDRGDYATAIQQL-KALN-REDVADV 92
Cdd:COG5010   11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLeQALQlDPNNPEL 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 496252754  93 ANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYHLDKVAQLA 154
Cdd:COG5010   91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 71-171 3.68e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 3.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754   71 RGDYATAIQQLKA---LNREDVADVANLIGYSYRKlGNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYHL 147
Cdd:TIGR02917 478 KGDLAKAREAFEKalsIEPDFFPAAANLARIDIQE-GNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWL 556

                          90       100
                  ....*....|....*....|....
gi 496252754  148 DKVAQLAGTNSPEYRSLADALEKQ 171
Cdd:TIGR02917 557 EKAAELNPQEIEPALALAQYYLGK 580
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 54-155 5.98e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.68  E-value: 5.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754   54 DPKFLAAYRTAYTSIYDRGDYATAIQQLKALNREDVADVA--NLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYG 131
Cdd:TIGR02917 325 APNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAalSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLG 404

                          90       100
                  ....*....|....*....|....
gi 496252754  132 LWQLEQGNREQAKYHLDKVAQLAG 155
Cdd:TIGR02917 405 ISKLSQGDPSEAIADLETAAQLDP 428
PGA_TPR_OMP TIGR03939
poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA; Members of this protein family are the ...
 99-172 6.96e-04

poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA; Members of this protein family are the poly-beta-1,6 N-acetyl-D-glucosamine (PGA) export porin PgaA of Gram-negative bacteria. There is no counterpart in the poly-beta-1,6 N-acetyl-D-glucosamine biosynthesis systems of Gram-positive bacteria such as Staphylococcus epidermidis. The PGA polysaccharide adhesin is a critical determinant of biofilm formation. The conserved C-terminal domain of this outer membrane protein is preceded by a variable number of TPR repeats.


Pssm-ID: 274868 [Multi-domain]  Cd Length: 800  Bit Score: 39.26  E-value: 6.96e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 496252754   99 SYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYHLDKVAQLAGTNSPEYRSLADALEKQP 172
Cdd:TIGR03939  95 AYRNEKQWDKALELYRKLLQRDPNNPDGLLGLALTLADAGKDAEALKYLKEYVARFPTDAARYEALAYVLRAAE 168
TPR_12 pfam13424
Tetratricopeptide repeat;
88-154 9.58e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.60  E-value: 9.58e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496252754   88 DVADVANLIGYSYRKLGNYQASKQYYEQALA--------DDPNHVRTWQYYGLWQLEQGNREQAKYHLDKVAQLA 154
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEiarrllgpDHPLTATTLLNLGRLYLELGRYEEALELLERALALA 75
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 111-175 2.94e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 36.14  E-value: 2.94e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496252754 111 QYYEQALADDPNHVRTWQYYGLWQLEQGNREQAKYHLDKVAQLAGTNSPEYRSLADALEKQPGTG 175
Cdd:COG4235    4 ARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTE 68
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
72-164 3.65e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 36.78  E-value: 3.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  72 GDYATAIQQLKALNRED----VADVANLIGYSYRKLGNYQASKQYYEQALADDPNhVRTWQYYGLWQLEQGNREQAKYHL 147
Cdd:COG4700  138 GRYAEALETLEKLIAKNpdfkSSDAHLLYARALEALGDLEAAEAELEALARRYSG-PEARYRYAKFLARQGRTAEAKELL 216

                         90
                 ....*....|....*..
gi 496252754 148 DKVAQLAGTNSPEYRSL 164
Cdd:COG4700  217 EEILDEAKHMPKHYRRL 233
tol_pal_ybgF TIGR02795
tol-pal system protein YbgF; Members of this protein family are the product of one of seven ...
 59-151 5.54e-03

tol-pal system protein YbgF; Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.


Pssm-ID: 188247 [Multi-domain]  Cd Length: 117  Bit Score: 34.95  E-value: 5.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754   59 AAYRTAYtSIYDRGDYATAIQQLKALNR-----EDVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRT---WQYY 130
Cdd:TIGR02795   2 AYYDAAL-LVLKAGDYADAIQAFQAFLKkypksTYAPNAHYWLGEAYYAQGDYADAAKAFLAVVKKYPKSPKApdaLLKL 80

                          90       100
                  ....*....|....*....|.
gi 496252754  131 GLWQLEQGNREQAKYHLDKVA 151
Cdd:TIGR02795  81 GMSLQELGDKEKAKATLQQVI 101
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
56-169 5.57e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 36.05  E-value: 5.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  56 KFLAAYRTAYTSIYDRGDYATAIQQLKALNREDVADVANLIGYSYRKLGNYQASKQYYEQALADDPNHVRTWQYYGLWQL 135
Cdd:COG4785   39 IALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYL 118

                         90       100       110
                 ....*....|....*....|....*....|....
gi 496252754 136 EQGNREQAKYHLDKVAQLAGTNSPEYRSLADALE 169
Cdd:COG4785  119 LLGDYDAALEDFDRALELDPDYAYAYLNRGIALY 152
ycf3 CHL00033
photosystem I assembly protein Ycf3
 71-160 6.27e-03

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 35.75  E-value: 6.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496252754  71 RGDYATAIQQ-LKALNRE-DVADVANL---IGYSYRKLGNYQASKQYYEQALADDPNHVRTW-------QYYGLWQLEQG 138
Cdd:CHL00033  48 EGEYAEALQNyYEAMRLEiDPYDRSYIlynIGLIHTSNGEHTKALEYYFQALERNPFLPQALnnmavicHYRGEQAIEQG 127

                         90       100
                 ....*....|....*....|....*....
gi 496252754 139 NREQAKYHLDKVA-------QLAGTNSPE 160
Cdd:CHL00033 128 DSEIAEAWFDQAAeywkqaiALAPGNYIE 156
TPR_1 pfam00515
Tetratricopeptide repeat;
90-123 6.55e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 33.16  E-value: 6.55e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 496252754   90 ADVANLIGYSYRKLGNYQASKQYYEQALADDPNH 123
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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