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Conserved domains on  [gi|497765133|ref|WP_010079317|]
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isoprenyl transferase [Micrococcus luteus]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 613)

undecaprenyl diphosphate synthase family protein such as isoprenyl transferase; belongs to the cis (Z)-isoprenyl diphosphate synthases (cis-IPPS), which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates, where a few family members can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP.

EC:  2.5.1.-
Gene Ontology:  GO:0004659|GO:0046872
PubMed:  12135472

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cis_IPPS super family cl00230
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 4-256 6.75e-127

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


The actual alignment was detected with superfamily member PRK14828:

Pssm-ID: 469674  Cd Length: 256  Bit Score: 360.22  E-value: 6.75e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133   4 PEAFYRLYERRLARGLDPERLPRHIGVLVDGNRRWARAFGAST-QQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENL 82
Cdd:PRK14828   6 RRLLYKVYARRLLGELDGAQVPGHVGIIVDGNRRWARKAGFTDvSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  83 RRPAEELAPLLEIIQTTAERLAqpAEGRAPVcvQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDA 162
Cdd:PRK14828  86 GRPSEELNPLLDIIEDVVRQLA--PDGRWRV--RHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 163 VRELLRDEHALGHSAAEVAESVTVEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFL 242
Cdd:PRK14828 162 VRSLLTEHKDKGTSIDELAESVTVDAISTHLYTGGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFL 241

                        250
                 ....*....|....
gi 497765133 243 RALRDYGSRQRRFG 256
Cdd:PRK14828 242 RALRDYSQRERRFG 255
 
Name Accession Description Interval E-value
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 4-256 6.75e-127

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 360.22  E-value: 6.75e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133   4 PEAFYRLYERRLARGLDPERLPRHIGVLVDGNRRWARAFGAST-QQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENL 82
Cdd:PRK14828   6 RRLLYKVYARRLLGELDGAQVPGHVGIIVDGNRRWARKAGFTDvSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  83 RRPAEELAPLLEIIQTTAERLAqpAEGRAPVcvQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDA 162
Cdd:PRK14828  86 GRPSEELNPLLDIIEDVVRQLA--PDGRWRV--RHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 163 VRELLRDEHALGHSAAEVAESVTVEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFL 242
Cdd:PRK14828 162 VRSLLTEHKDKGTSIDELAESVTVDAISTHLYTGGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFL 241

                        250
                 ....*....|....
gi 497765133 243 RALRDYGSRQRRFG 256
Cdd:PRK14828 242 RALRDYSQRERRFG 255
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
10-256 1.19e-110

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 318.54  E-value: 1.19e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  10 LYERRLARGLDPERLPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEEL 89
Cdd:COG0020    1 LYERALLPEIDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  90 APLLEIIQTT----AERLAQpaEGrapVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRE 165
Cdd:COG0020   81 SFLMGLLREYlrreLDELHK--NN---VRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRK 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 166 LLRDEHALGHSAAEVAEsvtvEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRAL 245
Cdd:COG0020  156 IARDVAAGELDPEDIDE----ETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAI 231

                        250
                 ....*....|.
gi 497765133 246 RDYGSRQRRFG 256
Cdd:COG0020  232 RDYQRRERRFG 242
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 33-256 2.03e-106

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 306.98  E-value: 2.03e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133   33 DGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQTTA---ERLAQPAEG 109
Cdd:pfam01255   3 DGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEEYlrrELPELHKNG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  110 rapVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDEHALGhsaaevAESVTVEQI 189
Cdd:pfam01255  83 ---VRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGKKLD------PEDIDEELI 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497765133  190 ADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFG 256
Cdd:pfam01255 154 SSHLYTAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 27-248 7.44e-105

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 302.75  E-value: 7.44e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  27 HIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQTTAERLAQP 106
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 107 AEgRAPVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDehalGHSAAEVAESVTV 186
Cdd:cd00475   81 LH-KNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARD----VKAGELDPEDITE 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497765133 187 EQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDY 248
Cdd:cd00475  156 ELISKHLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDY 217
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 26-256 1.71e-73

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 223.82  E-value: 1.71e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133   26 RHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQTTAERlAQ 105
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDR-EV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  106 PAEGRAPVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDeHALGHSAAEVAESVT 185
Cdd:TIGR00055  80 KELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEK-VKSGKLLPEDIDEET 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497765133  186 VEQiadRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFG 256
Cdd:TIGR00055 159 LNK---HLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
 
Name Accession Description Interval E-value
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 4-256 6.75e-127

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 360.22  E-value: 6.75e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133   4 PEAFYRLYERRLARGLDPERLPRHIGVLVDGNRRWARAFGAST-QQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENL 82
Cdd:PRK14828   6 RRLLYKVYARRLLGELDGAQVPGHVGIIVDGNRRWARKAGFTDvSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  83 RRPAEELAPLLEIIQTTAERLAqpAEGRAPVcvQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDA 162
Cdd:PRK14828  86 GRPSEELNPLLDIIEDVVRQLA--PDGRWRV--RHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 163 VRELLRDEHALGHSAAEVAESVTVEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFL 242
Cdd:PRK14828 162 VRSLLTEHKDKGTSIDELAESVTVDAISTHLYTGGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFL 241

                        250
                 ....*....|....
gi 497765133 243 RALRDYGSRQRRFG 256
Cdd:PRK14828 242 RALRDYSQRERRFG 255
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
10-256 1.19e-110

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 318.54  E-value: 1.19e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  10 LYERRLARGLDPERLPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEEL 89
Cdd:COG0020    1 LYERALLPEIDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  90 APLLEIIQTT----AERLAQpaEGrapVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRE 165
Cdd:COG0020   81 SFLMGLLREYlrreLDELHK--NN---VRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRK 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 166 LLRDEHALGHSAAEVAEsvtvEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRAL 245
Cdd:COG0020  156 IARDVAAGELDPEDIDE----ETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAI 231

                        250
                 ....*....|.
gi 497765133 246 RDYGSRQRRFG 256
Cdd:COG0020  232 RDYQRRERRFG 242
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 33-256 2.03e-106

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 306.98  E-value: 2.03e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133   33 DGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQTTA---ERLAQPAEG 109
Cdd:pfam01255   3 DGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEEYlrrELPELHKNG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  110 rapVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDEHALGhsaaevAESVTVEQI 189
Cdd:pfam01255  83 ---VRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGKKLD------PEDIDEELI 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497765133  190 ADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFG 256
Cdd:pfam01255 154 SSHLYTAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 27-248 7.44e-105

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 302.75  E-value: 7.44e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  27 HIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQTTAERLAQP 106
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 107 AEgRAPVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDehalGHSAAEVAESVTV 186
Cdd:cd00475   81 LH-KNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARD----VKAGELDPEDITE 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497765133 187 EQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDY 248
Cdd:cd00475  156 ELISKHLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDY 217
PRK14835 PRK14835
isoprenyl transferase;
6-256 3.10e-95

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 280.57  E-value: 3.10e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133   6 AFYRLYERRLARGLDPERLPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRP 85
Cdd:PRK14835  23 PLYWGYEQRLEREVKHGKLPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRS 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  86 AEELAPLLEIIQTTAERLAQPAEGRA-PVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVR 164
Cdd:PRK14835 103 PAEVETLMNLFEREARRMAVDPRIHAnRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGMLLNIAVGYGGREEIVDAVK 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 165 ELLRDEHALGHSAAEVAESVTVEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRA 244
Cdd:PRK14835 183 SLLLEAAATGKSPEEVAAELTPEHISAHLYTAGVPDPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRA 262

                        250
                 ....*....|..
gi 497765133 245 LRDYGSRQRRFG 256
Cdd:PRK14835 263 LRDYQGRERRFG 274
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 19-256 1.84e-76

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 232.07  E-value: 1.84e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  19 LDPERLPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLL----E 94
Cdd:PRK14830  17 LDKGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMnlpvE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  95 IIQTTAERLAQPAegrapVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDEHALG 174
Cdd:PRK14830  97 FLDKFVPELIENN-----VKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAVKEIAKDVLDGK 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 175 HSAaevaESVTVEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRR 254
Cdd:PRK14830 172 LNP----EDITEELISNYLMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQSRQRR 247


                 ..
gi 497765133 255 FG 256
Cdd:PRK14830 248 FG 249
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 26-256 1.71e-73

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 223.82  E-value: 1.71e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133   26 RHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQTTAERlAQ 105
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDR-EV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  106 PAEGRAPVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDeHALGHSAAEVAESVT 185
Cdd:TIGR00055  80 KELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEK-VKSGKLLPEDIDEET 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497765133  186 VEQiadRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFG 256
Cdd:TIGR00055 159 LNK---HLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 13-256 2.75e-71

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 218.66  E-value: 2.75e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  13 RRLARGLDPERLPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPL 92
Cdd:PRK14831   9 QDLPADLDPQRLPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  93 LEIIQTTAERLAQP--AEGrapVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELlrde 170
Cdd:PRK14831  89 MTLFERVLRRELEElmEEN---VRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAI---- 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 171 hALGHSAAEVAESVTVEQI-ADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYG 249
Cdd:PRK14831 162 -AQQVQQGELDPSEIDENLfESELYTAGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQ 240


                 ....*..
gi 497765133 250 SRQRRFG 256
Cdd:PRK14831 241 SRERRFG 247
PRK14838 PRK14838
isoprenyl transferase;
19-256 6.02e-64

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 199.71  E-value: 6.02e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  19 LDPERLPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQT 98
Cdd:PRK14838   5 IDMNRIPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSLLLD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  99 TAErlaQPAEGRAPVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELlrdehALGHSAA 178
Cdd:PRK14838  85 SIE---EETFMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQI-----ATLVQNG 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497765133 179 EVA-ESVTVEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFG 256
Cdd:PRK14838 157 ELNpEEITEESISEHLTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQKRERRFG 235
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 21-256 6.09e-63

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 197.60  E-value: 6.09e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  21 PERLPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQTTA 100
Cdd:PRK14836  11 NENIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELFLKAL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 101 ERlAQPAEGRAPVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDEHALGHSAAEV 180
Cdd:PRK14836  91 DR-EVDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKLAPDEI 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497765133 181 AESVtveqIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFG 256
Cdd:PRK14836 170 DEAL----LAQHLALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRERRFG 241
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 19-257 3.06e-62

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 195.99  E-value: 3.06e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  19 LDPERLPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQT 98
Cdd:PRK14832  13 LDPQKIPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLLFER 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  99 TAER-LAQpaEGRAPVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDEHALGHSA 177
Cdd:PRK14832  93 LLRReLAQ--MHREGVRISFIGDLSALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRQVAELVQQGKLSA 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 178 AEVAESVtVEQiadRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFGT 257
Cdd:PRK14832 171 DAVNEQL-VEQ---HLYTADTPPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQKRDRRFGQ 246
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 23-256 5.94e-61

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 192.13  E-value: 5.94e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  23 RLPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQTTAER 102
Cdd:PRK14841   2 RIPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIDR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 103 LAQPAEgRAPVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDehalghSAAEVAE 182
Cdd:PRK14841  82 EMELLR-RERVRVRILGRKEGLPEKVLKKWQEVEEKTKEFDRMTLVIAFNYGGRREILDAVESILKD------VSQGKKI 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497765133 183 SVTVEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFG 256
Cdd:PRK14841 155 ELTEETFRQYLYLPDVPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAIESYSKRERRFG 228
PRK14834 PRK14834
isoprenyl transferase;
18-256 5.22e-57

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 182.26  E-value: 5.22e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  18 GLDPERLPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQ 97
Cdd:PRK14834   8 ESDAMSVPRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLFGLLR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  98 TTAER-LAQPAegRAPVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELlrdehalghs 176
Cdd:PRK14834  88 LFIRRdLAELH--RNGVRVRVIGERAGLEADICALLNEAEELTRNNTGLNLVIAFNYGSRDEIARAVRRL---------- 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 177 AAEVAE------SVTVEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGS 250
Cdd:PRK14834 156 AREVAEgrldpaSIDAETISANLDTADIPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEYAR 235


                 ....*.
gi 497765133 251 RQRRFG 256
Cdd:PRK14834 236 RERRFG 241
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 22-257 5.94e-56

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 179.59  E-value: 5.94e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  22 ERLPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLL----EIIQ 97
Cdd:PRK14829  12 NKLPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMgfsrDVIH 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  98 TTAERLAQPAegrapVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDehalGHSA 177
Cdd:PRK14829  92 RRREQMDEWG-----VRVRWSGRRPRLWKSVIDELEAAEELTKNNTTMDLVFCVNYGGRAEIADAAAAIARE----VRDG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 178 AEVAESVTVEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFGT 257
Cdd:PRK14829 163 KISGDRVTEKMISDHLYNPDMPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEYAHRDRRFGG 242
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
24-256 2.29e-55

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 177.70  E-value: 2.29e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  24 LPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQttaERL 103
Cdd:PRK14833   4 TLKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLK---KYL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 104 AQPAEG--RAPVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLrDEHALGHSAAEVA 181
Cdd:PRK14833  81 KDERSTylENNIRFKAIGDLEGFSKELRDTILQLEEDTRSFKGFTQVLALNYGSKDEISRAFKKLL-ESPPSHIGELESL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497765133 182 EsvtvEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFG 256
Cdd:PRK14833 160 E----EEISNCLDTADLPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDFYKRVRKFG 230
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 22-256 1.03e-51

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 168.87  E-value: 1.03e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  22 ERLPRHIGVLVDGNRRWAR---AFGASTQ-QGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQ 97
Cdd:PRK14840  16 QSLPRHVAIIMDGNRRWYRkheQFCQKRAiSGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVAELFSLFN 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  98 TTA-ERLAQPAEGRapVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDEHALGHS 176
Cdd:PRK14840  96 SQLdSQLPYLHENE--IRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKLHQDLANKKIS 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 177 AAEVAEsvtvEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFG 256
Cdd:PRK14840 174 SDDISE----ELISSYLDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQQRSRRGG 249
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 18-256 8.75e-51

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 166.32  E-value: 8.75e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  18 GLDPERLPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAP----LL 93
Cdd:PRK14842   2 GLFESTIPAHIAVIMDGNGRWAESQGKKRSEGHREGANAIDRLMDASLEYGLKNISLYAFSTENWKRPITEIRSifglLV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  94 EIIQTTAERLAqpAEGrapVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLrdehal 173
Cdd:PRK14842  82 EFIETRLDTIH--ARG---IRIHHSGSRKKLTRTVLDKIDFAMAKTKKNKNLTVNFCLNYGSHDELLRAAQEVF------ 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 174 ghsAAEVAESVTVE------QIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRD 247
Cdd:PRK14842 151 ---LARKAKKVTLEkplkekEFEKFLYTSPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKW 227


                 ....*....
gi 497765133 248 YGSRQRRFG 256
Cdd:PRK14842 228 YETRTRKFG 236
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 22-257 5.97e-49

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 163.20  E-value: 5.97e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  22 ERLPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLL----EIIQ 97
Cdd:PRK14827  65 DRLPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMgfnrDVVR 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  98 TTAERLAQPAegrapVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDEHALGHSA 177
Cdd:PRK14827 145 RRRDNLNKMG-----VRIRWVGSRPRLWRSVINELAIAEEMTKSNDVITINYCVNYGGRTEITEATREIAREAAAGRLNP 219

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 178 AEVAESVtveqIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFGT 257
Cdd:PRK14827 220 ERITEST----IARHLQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFGS 295
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
27-257 1.46e-45

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 152.60  E-value: 1.46e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  27 HIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQT----TAER 102
Cdd:PRK14839  12 HVAIIMDGNGRWATARGLPRLAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNWRRPAAEVGGLMRLLRAylrnETER 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 103 LAqpaegRAPVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRellrdeHALGhsaaevAE 182
Cdd:PRK14839  92 LA-----RNGVRLTVIGRRDRLPDGIPEAIARAEAATAGGDRLHLRIAVDYSARDAILAAAA------KALG------PE 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497765133 183 SVTVEQIADRLyTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFGT 257
Cdd:PRK14839 155 GLSREAFSDLL-TGDGGDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFHGRERRFGG 228
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
32-256 2.31e-42

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 144.36  E-value: 2.31e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  32 VDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIQTTAERLAQPAEgRA 111
Cdd:PRK10240   1 MDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLH-RH 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 112 PVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRellrdehalgHSAAEVAE------SVT 185
Cdd:PRK10240  80 NVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVR----------QLAEQVQQgnlqpdQID 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497765133 186 VEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFG 256
Cdd:PRK10240 150 EEMLNQHICMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFG 220
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 24-256 3.70e-40

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 138.42  E-value: 3.70e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  24 LPRHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPLLEIIqttAERL 103
Cdd:PRK14837   6 LPSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLMFLI---ADYL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 104 AQPAEGRAPVCVQPV--GAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEILDAVRELLRDEHALghsaaeva 181
Cdd:PRK14837  83 SSEFNFYKKNNIKIIvsGDIESLSEEVKKSIKDAISFTKNFDGLVLNLAINYGGRNEIVRAVKKFLSSGLDL-------- 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497765133 182 ESVTVEQIADRLYTRGQPDPDLVIRTSGEQRLSGFLLWQSAYSEFYFCEAMWPAFRKVDFLRALRDYGSRQRRFG 256
Cdd:PRK14837 155 ETLNENVFSKFLDNPELPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEYYVNHYSKDLECFKNRKRNFG 229
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 26-248 1.23e-20

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 88.90  E-value: 1.23e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133  26 RHIGVLVDGNRRWARAFGASTQQGHQAGAERILDFIGWCDEAGIPVVTLYMLSTENLRRPAEELAPL--LEIIQTTAERL 103
Cdd:PTZ00349  21 KHISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPEEIHFLfyLNLLILINEDF 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 104 AQPAEGRAPVCVQPVGAVDLLPEPMARRLAEVAEQTKDHDGVHVNVAVGYGGRQEI----------LDAVRELLRD---- 169
Cdd:PTZ00349 101 FFKFIKDNKIKIKIIGNLSYINDAYRKIIHDIEEKTENFDNILLNIFFSYTSRNEMslckfnpnlyFDTYKNLLEEkkil 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497765133 170 ---------------------------EHALGHSAAEVAESVTV------------EQIA-----DRLYTRGQPDPDLVI 205
Cdd:PTZ00349 181 cgsniltdpikegtfaipddedecdylDHELENERIDLDLKFDGdcicgeksflneEQIEivnyhKKLLTSDLPPPNILI 260

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 497765133 206 RTSGEQRLSGFLLWQ-SAYSEFYFCEAMWPAFRKVDFLRALRDY 248
Cdd:PTZ00349 261 RTSGEKRLSDFMLYQiSEFTEIYFINEYWPIFNFLQFIYIILHY 304
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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