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Conserved domains on  [gi|499416016|ref|WP_011103483|]
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mannuronan 5-epimerase AlgG [Pseudomonas syringae group genomosp. 3]

Protein Classification

right-handed parallel beta-helix repeat-containing protein( domain architecture ID 17609036)

right-handed parallel beta-helix repeat-containing protein that may share some similarity with pectate lyases, similar to Pseudomonas putida mannuronan C5-epimerase that catalyzes the epimerization of beta-D-mannuronate to alpha-L-guluronate during the synthesis of the linear polysaccharide alginate

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
epimerase_AlgG super family cl45661
mannuronan 5-epimerase AlgG;
18-536 0e+00

mannuronan 5-epimerase AlgG;


The actual alignment was detected with superfamily member NF038177:

Pssm-ID: 468398 [Multi-domain]  Cd Length: 519  Bit Score: 1059.07  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016  18 LESALLTSALLMASSVALANAPAVPEAPKALVKELHQAKTYTITSPPTGPLEMAKPVLPDLSGYTTEAALKKIARNKPGK 97
Cdd:NF038177   1 LLSALLLGALLLASGAAQAAVPAQPEAPRQLAKELQQAKTYTVTSAPIEPLEMDPPKLPDLSGYTAAAVEKKIVRKPGGK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016  98 ITVARMMEETGLKEFIGGDNKMAEWVVRQKGIPQAIMISDGYVNLQDLVKKVPKQFLSEVSPGVYVARLPILVKETGIFE 177
Cdd:NF038177  81 ISVARMMQETALKEFTGGDNKLAEWVVRQHGIPQAIFIEDGYVNLGQLAKKVPKQYLSEVEPGVYVARLPIVVGQGGILE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 178 IDSKTKELRLSQEKGSFIVSEGKMLITNTSVNAWSETRNGLAAYRTPDEFRPFVLTWGGSQTWIAKTKMASMGYNQSKSY 257
Cdd:NF038177 161 IDKKVKELRLSQERGAFLVNDGKLFVTDTKVTGWSEKNNGPAAYRTPKEFRPFLLSWGGTETYISNTKMASFGYNTSKSY 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 258 GVSISQYTPNTAKVLKRGEPTGWIIDSEFADMWYGFYCYETRDFVVKGNTYRDNIVYGIDPHDRSHGLIIAENDVYGTKK 337
Cdd:NF038177 241 GVSISQYTPNMAKRLKRPEPTGWIIDSEFSDMWYGFYCYETDDFVVKGNTYRDNIVYGIDPHDRSHRLIIAENTVYGTKK 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 338 KHGIIISREVDNSFIFRNKSHNNKLSGVVLDRNSVGNIVAYNEIYQNHTDGITLYESGNNLLWGNRVIANRRHGIRVRNS 417
Cdd:NF038177 321 KHGIIVSREVNDSFIFNNRSYDNKLSGIVLDRNSVGNLVAYNEVYRNHTDGITLYESGDNLLWGNRVIANRRHGIRVRNS 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 418 VNIKLYENVAMANGLMGVYGHIKDLNDTDRDIELDPFDAQVSLIMVGGELSSNGSGPLSIDSPLSVELYRVSMLMPTKEV 497
Cdd:NF038177 401 VNIRLYENLAMANGLTGVYGHIKDLSDTDRDIALDPFDTKVSLIVVGGELSGNGSGPLSIDSPLSVELYRVSMLAPTKSS 480

                        490       500       510
                 ....*....|....*....|....*....|....*....
gi 499416016 498 GISLNGILGERQDEILDLLVRQKKAVLIDPVESQTELRE 536
Cdd:NF038177 481 GISLNGVLGERQDEILDLLVRQQKAVLIDPVESQTELQD 519
 
Name Accession Description Interval E-value
epimerase_AlgG NF038177
mannuronan 5-epimerase AlgG;
18-536 0e+00

mannuronan 5-epimerase AlgG;


Pssm-ID: 468398 [Multi-domain]  Cd Length: 519  Bit Score: 1059.07  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016  18 LESALLTSALLMASSVALANAPAVPEAPKALVKELHQAKTYTITSPPTGPLEMAKPVLPDLSGYTTEAALKKIARNKPGK 97
Cdd:NF038177   1 LLSALLLGALLLASGAAQAAVPAQPEAPRQLAKELQQAKTYTVTSAPIEPLEMDPPKLPDLSGYTAAAVEKKIVRKPGGK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016  98 ITVARMMEETGLKEFIGGDNKMAEWVVRQKGIPQAIMISDGYVNLQDLVKKVPKQFLSEVSPGVYVARLPILVKETGIFE 177
Cdd:NF038177  81 ISVARMMQETALKEFTGGDNKLAEWVVRQHGIPQAIFIEDGYVNLGQLAKKVPKQYLSEVEPGVYVARLPIVVGQGGILE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 178 IDSKTKELRLSQEKGSFIVSEGKMLITNTSVNAWSETRNGLAAYRTPDEFRPFVLTWGGSQTWIAKTKMASMGYNQSKSY 257
Cdd:NF038177 161 IDKKVKELRLSQERGAFLVNDGKLFVTDTKVTGWSEKNNGPAAYRTPKEFRPFLLSWGGTETYISNTKMASFGYNTSKSY 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 258 GVSISQYTPNTAKVLKRGEPTGWIIDSEFADMWYGFYCYETRDFVVKGNTYRDNIVYGIDPHDRSHGLIIAENDVYGTKK 337
Cdd:NF038177 241 GVSISQYTPNMAKRLKRPEPTGWIIDSEFSDMWYGFYCYETDDFVVKGNTYRDNIVYGIDPHDRSHRLIIAENTVYGTKK 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 338 KHGIIISREVDNSFIFRNKSHNNKLSGVVLDRNSVGNIVAYNEIYQNHTDGITLYESGNNLLWGNRVIANRRHGIRVRNS 417
Cdd:NF038177 321 KHGIIVSREVNDSFIFNNRSYDNKLSGIVLDRNSVGNLVAYNEVYRNHTDGITLYESGDNLLWGNRVIANRRHGIRVRNS 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 418 VNIKLYENVAMANGLMGVYGHIKDLNDTDRDIELDPFDAQVSLIMVGGELSSNGSGPLSIDSPLSVELYRVSMLMPTKEV 497
Cdd:NF038177 401 VNIRLYENLAMANGLTGVYGHIKDLSDTDRDIALDPFDTKVSLIVVGGELSGNGSGPLSIDSPLSVELYRVSMLAPTKSS 480

                        490       500       510
                 ....*....|....*....|....*....|....*....
gi 499416016 498 GISLNGILGERQDEILDLLVRQKKAVLIDPVESQTELRE 536
Cdd:NF038177 481 GISLNGVLGERQDEILDLLVRQQKAVLIDPVESQTELQD 519
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 291-436 6.56e-15

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 72.44  E-value: 6.56e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016  291 YGFYCYETRDFVVKGNTYRDNIVYGIDPHDrSHGLIIAENDVYGTKKkHGIIISREVDNSFIfRNKSHNNKLSGVVLdRN 370
Cdd:pfam13229   1 SGILLNGSSNATIKNNTISNNGGYGIYLRG-SSNATIENNTITNNGG-DGIEISGSSNNTIS-NNTISNNGGGGIAL-RG 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499416016  371 SVGNIVAYNEIYQNHTDGITLYESGNNLLWGNRVIANRRHGIRV-RNSVNIKLYENVAMANGLMGVY 436
Cdd:pfam13229  77 SSNNLIENNTISNNGGAGIYLSDSSNNTIENNIIHNNGGSGIVIeDSSNNVTISNNTVTNNKGAGIL 143
NosD COG3420
Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion ...
 281-436 5.87e-14

Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion transport and metabolism];


Pssm-ID: 442646 [Multi-domain]  Cd Length: 343  Bit Score: 73.03  E-value: 5.87e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 281 IIDSEFADMWYGFYCYETRDFVVKGNTYRDNIVYGIDPHD-----RSHGLIIAENDVYGTKkkHGIIISReVDNSFIFRN 355
Cdd:COG3420  111 IENNRIENNLFGIYLEGSDNNVIRNNTISGNRDLRADRGNgihlwNSPGNVIEGNTISGGR--DGIYLEF-SDNNVIRNN 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 356 K------------SHNNKLSGVVLDRNSVG--------NIVAYNEIYQNHTDGITLYESGNNLLWGNRVIANRRhGIRVR 415
Cdd:COG3420  188 TirnlrygihymySNDNLVEGNTFRDNGAGialmyskgNTVRGNTILGNSGYGILLKESSDSVIEGNTISGNGK-GIFIY 266

                        170       180
                 ....*....|....*....|.
gi 499416016 416 NSVNIKLYENVAMANGlMGVY 436
Cdd:COG3420  267 NSNRNTIRGNLFAGNG-IGIH 286
CASH smart00722
Domain present in carbohydrate binding proteins and sugar hydrolses;
299-415 3.44e-08

Domain present in carbohydrate binding proteins and sugar hydrolses;


Pssm-ID: 214788  Cd Length: 153  Bit Score: 52.89  E-value: 3.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016   299 RDFVVKGNTYRDNIVYGIDPHDRSHGLII--AENDVYG----TKKKHGIIISREVDNSFI---FRNKSHNNKLSGVVLDR 369
Cdd:smart00722  26 GGAVIDMGSGRGSNITINSNDVRVDGVTIggDGNAVTGiyvsASGDPVIQNDGTGKNLIIdnvTFNGTEINSGAGIVVTA 105

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 499416016   370 NSVGNIVaYNEI---YQNHTDGITLYESGNNLLWGNRVIANRRHGIRVR 415
Cdd:smart00722 106 GSEGLFI-GNRIignYVATGDGNYLSDSSGGDLIGNRIYDNNRDGIAVV 153
para_beta_helix TIGR03804
parallel beta-helix repeat (two copies); This model represents a tandem pair of an ...
 364-409 7.48e-03

parallel beta-helix repeat (two copies); This model represents a tandem pair of an approximately 22-amino acid (each) repeat homologous to the beta-strand repeats that stack in a right-handed parallel beta-helix in the periplasmic C-5 mannuronan epimerase, AlgA, of Pseudomonas aeruginosa. A homology domain consisting of a longer tandem array of these repeats is described in the SMART database as CASH (SM00722), and is found in many carbohydrate-binding proteins and sugar hydrolases. A single repeat is represented by SM00710. This TIGRFAMs model represents a flavor of the parallel beta-helix-forming repeat based on prokaryotic sequences only in its seed alignment, although it also finds many eukaryotic sequences.


Pssm-ID: 274795 [Multi-domain]  Cd Length: 44  Bit Score: 34.41  E-value: 7.48e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 499416016  364 GVVLDrNSVGNIVAYNEIYQNhTDGITLYESGNNLLWGNRVIANRR 409
Cdd:TIGR03804   1 GIYLE-SSSNNTLSNNTASNN-SYGIYLYDSSNNTLSNNTASNNGY 44
 
Name Accession Description Interval E-value
epimerase_AlgG NF038177
mannuronan 5-epimerase AlgG;
18-536 0e+00

mannuronan 5-epimerase AlgG;


Pssm-ID: 468398 [Multi-domain]  Cd Length: 519  Bit Score: 1059.07  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016  18 LESALLTSALLMASSVALANAPAVPEAPKALVKELHQAKTYTITSPPTGPLEMAKPVLPDLSGYTTEAALKKIARNKPGK 97
Cdd:NF038177   1 LLSALLLGALLLASGAAQAAVPAQPEAPRQLAKELQQAKTYTVTSAPIEPLEMDPPKLPDLSGYTAAAVEKKIVRKPGGK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016  98 ITVARMMEETGLKEFIGGDNKMAEWVVRQKGIPQAIMISDGYVNLQDLVKKVPKQFLSEVSPGVYVARLPILVKETGIFE 177
Cdd:NF038177  81 ISVARMMQETALKEFTGGDNKLAEWVVRQHGIPQAIFIEDGYVNLGQLAKKVPKQYLSEVEPGVYVARLPIVVGQGGILE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 178 IDSKTKELRLSQEKGSFIVSEGKMLITNTSVNAWSETRNGLAAYRTPDEFRPFVLTWGGSQTWIAKTKMASMGYNQSKSY 257
Cdd:NF038177 161 IDKKVKELRLSQERGAFLVNDGKLFVTDTKVTGWSEKNNGPAAYRTPKEFRPFLLSWGGTETYISNTKMASFGYNTSKSY 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 258 GVSISQYTPNTAKVLKRGEPTGWIIDSEFADMWYGFYCYETRDFVVKGNTYRDNIVYGIDPHDRSHGLIIAENDVYGTKK 337
Cdd:NF038177 241 GVSISQYTPNMAKRLKRPEPTGWIIDSEFSDMWYGFYCYETDDFVVKGNTYRDNIVYGIDPHDRSHRLIIAENTVYGTKK 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 338 KHGIIISREVDNSFIFRNKSHNNKLSGVVLDRNSVGNIVAYNEIYQNHTDGITLYESGNNLLWGNRVIANRRHGIRVRNS 417
Cdd:NF038177 321 KHGIIVSREVNDSFIFNNRSYDNKLSGIVLDRNSVGNLVAYNEVYRNHTDGITLYESGDNLLWGNRVIANRRHGIRVRNS 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 418 VNIKLYENVAMANGLMGVYGHIKDLNDTDRDIELDPFDAQVSLIMVGGELSSNGSGPLSIDSPLSVELYRVSMLMPTKEV 497
Cdd:NF038177 401 VNIRLYENLAMANGLTGVYGHIKDLSDTDRDIALDPFDTKVSLIVVGGELSGNGSGPLSIDSPLSVELYRVSMLAPTKSS 480

                        490       500       510
                 ....*....|....*....|....*....|....*....
gi 499416016 498 GISLNGILGERQDEILDLLVRQKKAVLIDPVESQTELRE 536
Cdd:NF038177 481 GISLNGVLGERQDEILDLLVRQQKAVLIDPVESQTELQD 519
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 291-436 6.56e-15

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 72.44  E-value: 6.56e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016  291 YGFYCYETRDFVVKGNTYRDNIVYGIDPHDrSHGLIIAENDVYGTKKkHGIIISREVDNSFIfRNKSHNNKLSGVVLdRN 370
Cdd:pfam13229   1 SGILLNGSSNATIKNNTISNNGGYGIYLRG-SSNATIENNTITNNGG-DGIEISGSSNNTIS-NNTISNNGGGGIAL-RG 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499416016  371 SVGNIVAYNEIYQNHTDGITLYESGNNLLWGNRVIANRRHGIRV-RNSVNIKLYENVAMANGLMGVY 436
Cdd:pfam13229  77 SSNNLIENNTISNNGGAGIYLSDSSNNTIENNIIHNNGGSGIVIeDSSNNVTISNNTVTNNKGAGIL 143
NosD COG3420
Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion ...
 281-436 5.87e-14

Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion transport and metabolism];


Pssm-ID: 442646 [Multi-domain]  Cd Length: 343  Bit Score: 73.03  E-value: 5.87e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 281 IIDSEFADMWYGFYCYETRDFVVKGNTYRDNIVYGIDPHD-----RSHGLIIAENDVYGTKkkHGIIISReVDNSFIFRN 355
Cdd:COG3420  111 IENNRIENNLFGIYLEGSDNNVIRNNTISGNRDLRADRGNgihlwNSPGNVIEGNTISGGR--DGIYLEF-SDNNVIRNN 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 356 K------------SHNNKLSGVVLDRNSVG--------NIVAYNEIYQNHTDGITLYESGNNLLWGNRVIANRRhGIRVR 415
Cdd:COG3420  188 TirnlrygihymySNDNLVEGNTFRDNGAGialmyskgNTVRGNTILGNSGYGILLKESSDSVIEGNTISGNGK-GIFIY 266

                        170       180
                 ....*....|....*....|.
gi 499416016 416 NSVNIKLYENVAMANGlMGVY 436
Cdd:COG3420  267 NSNRNTIRGNLFAGNG-IGIH 286
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 281-427 2.87e-11

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 61.65  E-value: 2.87e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016  281 IIDSEFADM-WYGFYCYETRDFVVKGNTYRDNIVYGIDPHDRSHGLI----IAENDVYGtkkkhgiIISREVDNSFIFRN 355
Cdd:pfam13229  13 IKNNTISNNgGYGIYLRGSSNATIENNTITNNGGDGIEISGSSNNTIsnntISNNGGGG-------IALRGSSNNLIENN 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499416016  356 KSHNNKLSGVVLDRNSvGNIVAYNEIYQNHTDGITLYESGNNL-LWGNRVIANRRHGIRVRNSV-NIKLYENVA 427
Cdd:pfam13229  86 TISNNGGAGIYLSDSS-NNTIENNIIHNNGGSGIVIEDSSNNVtISNNTVTNNKGAGILIVGGSsNNTVENNTF 158
NosD COG3420
Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion ...
 281-420 4.69e-10

Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion transport and metabolism];


Pssm-ID: 442646 [Multi-domain]  Cd Length: 343  Bit Score: 61.09  E-value: 4.69e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016 281 IIDSEFADMWYGFYCYETRDFVVKGNTYRDNIVyGIDPHDrSHGLIIAENDVYGTKKkHGIIIsREVDNSFIFRNKSHNN 360
Cdd:COG3420  184 IRNNTIRNLRYGIHYMYSNDNLVEGNTFRDNGA-GIALMY-SKGNTVRGNTILGNSG-YGILL-KESSDSVIEGNTISGN 259

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499416016 361 KlSGVVLDrNSVGNIVAYNEIYQNHTdGITLY-ESGNNLLWGNRVIANRRHGIRVRNSVNI 420
Cdd:COG3420  260 G-KGIFIY-NSNRNTIRGNLFAGNGI-GIHLTaGSEGNRIYGNNFIGNRTQVKYVGGRDNE 317
NosD pfam05048
Periplasmic copper-binding protein (NosD); NosD is a periplasmic protein which is thought to ...
 310-436 1.07e-08

Periplasmic copper-binding protein (NosD); NosD is a periplasmic protein which is thought to insert copper into the exported reductase apoenzyme (NosZ). This region forms a parallel beta helix domain.


Pssm-ID: 428281 [Multi-domain]  Cd Length: 215  Bit Score: 55.50  E-value: 1.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016  310 DNIVYGiDPHDRSHGLIIaENDVYGTKKKHGIIISREVDNS--FIFRNKSHNNKLSGVVLDRNSVG--------NIVAYN 379
Cdd:pfam05048   2 NNAISG-DTIGIYNGLSR-GNGIQLWNTEGNVISNNDIINSrdGIYLDASNNNTITGNRISNLRYGihlmnsndNTISDN 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 499416016  380 EIYQNhTDGITLYESGNNLLWGNRVIANRRHGIRVRNSVNIKLYENVAMANGLMGVY 436
Cdd:pfam05048  80 VFSGN-TAGIALMSSSNNTLENNTISGNTNYGILLSDSSNNTISNNTISNNNGKGIF 135
CASH smart00722
Domain present in carbohydrate binding proteins and sugar hydrolses;
299-415 3.44e-08

Domain present in carbohydrate binding proteins and sugar hydrolses;


Pssm-ID: 214788  Cd Length: 153  Bit Score: 52.89  E-value: 3.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016   299 RDFVVKGNTYRDNIVYGIDPHDRSHGLII--AENDVYG----TKKKHGIIISREVDNSFI---FRNKSHNNKLSGVVLDR 369
Cdd:smart00722  26 GGAVIDMGSGRGSNITINSNDVRVDGVTIggDGNAVTGiyvsASGDPVIQNDGTGKNLIIdnvTFNGTEINSGAGIVVTA 105

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 499416016   370 NSVGNIVaYNEI---YQNHTDGITLYESGNNLLWGNRVIANRRHGIRVR 415
Cdd:smart00722 106 GSEGLFI-GNRIignYVATGDGNYLSDSSGGDLIGNRIYDNNRDGIAVV 153
NosD pfam05048
Periplasmic copper-binding protein (NosD); NosD is a periplasmic protein which is thought to ...
 252-425 9.94e-08

Periplasmic copper-binding protein (NosD); NosD is a periplasmic protein which is thought to insert copper into the exported reductase apoenzyme (NosZ). This region forms a parallel beta helix domain.


Pssm-ID: 428281 [Multi-domain]  Cd Length: 215  Bit Score: 52.81  E-value: 9.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016  252 NQSKSYGVSISQYTPNTAKVLKRGEPTGWIIDSEFADMWYGFYCYETRDFVVKGNTYRDNiVYGIdpH-DRSHGLIIAEN 330
Cdd:pfam05048   3 NAISGDTIGIYNGLSRGNGIQLWNTEGNVISNNDIINSRDGIYLDASNNNTITGNRISNL-RYGI--HlMNSNDNTISDN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016  331 DVYGTKKkhGIIISREVDNsFIFRNKSHNNKLSGVVLDrNSVGNIVAYNEIYQNHTDGITLYESGNNLLWGNRVIANrRH 410
Cdd:pfam05048  80 VFSGNTA--GIALMSSSNN-TLENNTISGNTNYGILLS-DSSNNTISNNTISNNNGKGIFLYNSDYNTITGNRITSN-GI 154

                         170
                  ....*....|....*.
gi 499416016  411 GIRVRN-SVNIKLYEN 425
Cdd:pfam05048 155 GIHFLAgSNGNTIYNN 170
NosD pfam05048
Periplasmic copper-binding protein (NosD); NosD is a periplasmic protein which is thought to ...
 292-436 1.72e-05

Periplasmic copper-binding protein (NosD); NosD is a periplasmic protein which is thought to insert copper into the exported reductase apoenzyme (NosZ). This region forms a parallel beta helix domain.


Pssm-ID: 428281 [Multi-domain]  Cd Length: 215  Bit Score: 45.87  E-value: 1.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499416016  292 GFYCYETRDFVVKGNT---YRDNIVygidpHDRSHGLIIAENDVYGTKkkHGIIISrEVDNSFIFRNKSHNNKlSGVVLD 368
Cdd:pfam05048  21 GIQLWNTEGNVISNNDiinSRDGIY-----LDASNNNTITGNRISNLR--YGIHLM-NSNDNTISDNVFSGNT-AGIALM 91

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499416016  369 rNSVGNIVAYNEIYQNHTDGITLYESGNNLLWGNRVIANRRHGIRVRNSVNIKLYENVAMANGLmGVY 436
Cdd:pfam05048  92 -SSSNNTLENNTISGNTNYGILLSDSSNNTISNNTISNNNGKGIFLYNSDYNTITGNRITSNGI-GIH 157
para_beta_helix TIGR03804
parallel beta-helix repeat (two copies); This model represents a tandem pair of an ...
 364-409 7.48e-03

parallel beta-helix repeat (two copies); This model represents a tandem pair of an approximately 22-amino acid (each) repeat homologous to the beta-strand repeats that stack in a right-handed parallel beta-helix in the periplasmic C-5 mannuronan epimerase, AlgA, of Pseudomonas aeruginosa. A homology domain consisting of a longer tandem array of these repeats is described in the SMART database as CASH (SM00722), and is found in many carbohydrate-binding proteins and sugar hydrolases. A single repeat is represented by SM00710. This TIGRFAMs model represents a flavor of the parallel beta-helix-forming repeat based on prokaryotic sequences only in its seed alignment, although it also finds many eukaryotic sequences.


Pssm-ID: 274795 [Multi-domain]  Cd Length: 44  Bit Score: 34.41  E-value: 7.48e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 499416016  364 GVVLDrNSVGNIVAYNEIYQNhTDGITLYESGNNLLWGNRVIANRR 409
Cdd:TIGR03804   1 GIYLE-SSSNNTLSNNTASNN-SYGIYLYDSSNNTLSNNTASNNGY 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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