|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1050 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1376.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 1 MIDRILEFALRQRVFVLLGALLLVVVGSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMT 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 81 ELRSLSKTGLSQVTLVFEDGVDVYRVRQLVSERLAGAAKELPAGLTPMLAPITSGLSDIFYYVVDyaenaPDKPATRAEQ 160
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLE-----SDPGKYSLME 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 161 LRELQlihDFVIKPQLRTVRGVVEVNASGGYEKQIIVQPRPDALLAAGVTFHELAEIVGENVENAGGGAVQIGGEQLSIR 240
Cdd:COG3696 156 LRTLQ---DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 241 ADSRVRSTEEISRLPLKFRGAgiAPLLVSDVADVVVGSSLRTGTATHNGR-EALLGAALMLTGENARLVARRVADKLAEI 319
Cdd:COG3696 233 GIGLIRSLEDIENIVVKTRNG--TPVLLRDVAEVRIGPAPRRGAATLNGEgEVVGGIVLMLKGENALEVIEAVKAKLAEL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 320 QPRLPAGVTLTTVYDRTDLVDRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLM 399
Cdd:COG3696 311 KPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLM 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 400 SLG--AVDFGLIIDGAVVMVENIVRRIGARQHAvgrdLTREERLHTVLAAAKEVGRPTFFGVAIITLVYVPILSLTGIEG 477
Cdd:COG3696 391 SLGglAIDFGIIVDGAVVMVENILRRLEENRAA----GTPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEG 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 478 KMFEPMALTVIFALIGALILTLTLMPVLCSFGLRGRVAEGDGWLVRALKRLYVPVLARALRWRWAVVGGGLALCGLAAAL 557
Cdd:COG3696 467 KLFRPMALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALAL 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 558 FGRLGAEFVPQLDEGSFATFMIRTNSIGLEASLAMQERGERLLREkFPLVTHTFSRIGTAEVATDPMGVNVADTYIFYRP 637
Cdd:COG3696 547 FPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKS-FPEVESVVSRTGRAEDATDPMGVNMSETFVILKP 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 638 FAEWPrdehgDGPTKDEVADAMAEILGThLPGEAHLFSQPIEMRFNEILEGTRADIAVKVFGDDFERIEAIASEVREILE 717
Cdd:COG3696 626 RSEWR-----SGRTKEELIAEMREALEQ-IPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLK 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 718 QVPGAADVEFDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLRSALEELKH 797
Cdd:COG3696 700 TVPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRN 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 798 LPLRLAHAdGVITLGDVAEFVVTEKVNAIARESGQRRAAIMVNLRGRDVESFVHEAQARVRAQVELPAGYAIEFGGQFKN 877
Cdd:COG3696 780 LPIPTPSG-AQVPLSQVADIEVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFEN 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 878 LQEARGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVAVLNGLML 957
Cdd:COG3696 859 LQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVL 938
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 958 VSTFNQLREEGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTLVMLPVLY 1037
Cdd:COG3696 939 VSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALY 1018
|
1050
....*....|...
gi 501344150 1038 EWSEARLARRRAE 1050
Cdd:COG3696 1019 LLFGRRRLRRAAA 1031
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1054 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 1105.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 1 MIDRILEFALRQRVFVLLGALLLVVVGSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMT 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 81 ELRSLSKTGLSQVTLVFEDGVDVYRVRQLVSERLAGAAKELPAGLTPMLAPITSGLSDIFYYVVDYAENAPDKPAtRAEQ 160
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGARKKDG-GAYT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 161 LRELQLIHDFVIKPQLRTVRGVVEVNASGGYEKQIIVQPRPDALLAAGVTFHELAEIVGENVENAGGGAVQIGGEQLSIR 240
Cdd:TIGR00914 160 LTDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 241 ADSRVRSTEEISRLPLKfRGAGIaPLLVSDVADVVVGSSLRTGTATHNGREALLGAALMLTGENARLVARRVADKLAEIQ 320
Cdd:TIGR00914 240 APGQVQSMDDIRNIVIA-TGEGV-PIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETIN 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 321 PRLPAGVTLTTVYDRTDLVDRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMS 400
Cdd:TIGR00914 318 KTLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMS 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 401 LGAVDFGLIIDGAVVMVENIVRRIGARQHAVGRDLTREERLHTVLAAAKEVGRPTFFGVAIITLVYVPILSLTGIEGKMF 480
Cdd:TIGR00914 398 LGALDFGLIVDGAVVIVENAHRRLAEAQHHHGRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMF 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 481 EPMALTVIFALIGALILTLTLMPVLCSFGLRGRVAEGDGWLVRALKRLYVPVLARALRWRWAVVGGGLALCGLAAALFGR 560
Cdd:TIGR00914 478 HPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASR 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 561 LGAEFVPQLDEGSFATFMIRTNSIGLEASLAMQERGERLLReKFPLVTHTFSRIGTAEVATDPMGVNVADTYIFYRPFAE 640
Cdd:TIGR00914 558 VGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIK-SFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPESQ 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 641 WPrdehgdgPTKDEVADAMAEIL--GTHLPGEAHLFSQPIEMRFNEILEGTRADIAVKVFGDDFERIEAIASEVREILEQ 718
Cdd:TIGR00914 637 WP-------EGKKTKEDLIEEIQeaTVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKG 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 719 VPGAADVEFDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLRSALEELKHL 798
Cdd:TIGR00914 710 VPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQL 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 799 PLRLAHADGV----ITLGDVAEFVVTEKVNAIARESGQRRAAIMVNLRGRDVESFVHEAQARVRAQVELPAGYAIEFGGQ 874
Cdd:TIGR00914 790 PIPLPLSEDArkqfIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQ 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 875 FKNLQEARGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVAVLNG 954
Cdd:TIGR00914 870 FEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNG 949
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 955 LMLVSTFNQLREEGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTLVMLP 1034
Cdd:TIGR00914 950 LVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLP 1029
|
1050 1060
....*....|....*....|
gi 501344150 1035 VLYEWSEARLARRRAEGKTL 1054
Cdd:TIGR00914 1030 ALYRLVHRRRHKGRKEHEPL 1049
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1037 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 866.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 5 ILEFALRQRVFVLLGALLLVVVGSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMTELRS 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 85 LSKTGLSQVTLVFEDGVDVYRVRQLVSERLAGAAKELPAGL-TPMLAPITSGLSDIFYYVVDyaenaPDKPATRAEQLRE 163
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVqRPGISVIKTSLGPIMVLAVT-----SPDGSYTQTDLRD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 164 LQlihDFVIKPQLRTVRGVVEVNASGGYEKQIIVQPRPDALLAAGVTFHELAEIVGENVENAGGGAVQIGGEQLSIRADS 243
Cdd:pfam00873 156 YA---DTNIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 244 RVRSTEEISRLPLKfrGAGIAPLLVSDVADVVVGSSLRTGTATHNGREALLGAALMLTGENARLVARRVADKLAEIQPRL 323
Cdd:pfam00873 233 QLQSAEDFEKIIVK--NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTF 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 324 PAGVTLTTVYDRTDLVDRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMSLGA 403
Cdd:pfam00873 311 PQGVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGG 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 404 VDF--GLIIDGAVVMVENIVRRIGARQhavgrdltrEERLHTVLAAAKEVGRPTFFGVAIITLVYVPILSLTGIEGKMFE 481
Cdd:pfam00873 391 LVLaiGLVVDDAIVVVENIERVLEENG---------LKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFR 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 482 PMALTVIFALIGALILTLTLMPVLCSFGLRGRVAEGDGW-------LVRALKRLYVPVLARALRWRWAVVGGGLALCGLA 554
Cdd:pfam00873 462 QFAITIVLAILLSVLVALTLTPALCATLLKPRREPKHGGffrwfnrMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGS 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 555 AALFGRLGAEFVPQLDEGSFATFMIRTNSIGLEASLAMQERGERLLREkFPLVTHTFSRIGTAEvATDPMGVNVADTYIF 634
Cdd:pfam00873 542 VWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKE-KPEVESVFAVTGFAF-SGDNNGPNSGDAFIS 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 635 YRPFAEWPRDEHgdgpTKDEVADAMAEILGThLPGEAHLFSQPIEMRFNEILEGTRADIAVKVFGDDFERIEAIASEVRE 714
Cdd:pfam00873 620 LKPWKERPGPEK----SVQALIERLRKALKQ-IPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILA 694
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 715 ILEQVPGAADVEFDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLRSALEE 794
Cdd:pfam00873 695 ALAQLPGLSDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPED 774
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 795 LKHLPLRLAHaDGVITLGDVAEFVVTEKVNAIARESGQRRAAIMVNLRGRDVESFVHEAQARVRAQVELPAGYAIEFGGQ 874
Cdd:pfam00873 775 IGQLYVRNPY-GKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQ 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 875 FKNLQEARGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVAVLNG 954
Cdd:pfam00873 854 FEQEQLAGNSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNA 933
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 955 LMLVSTFNQLRE-EGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTLVML 1033
Cdd:pfam00873 934 ILMVEFANELREqEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVV 1013
|
....
gi 501344150 1034 PVLY 1037
Cdd:pfam00873 1014 PVFY 1017
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
27-1037 |
6.05e-133 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 427.90 E-value: 6.05e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 27 GSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMTELRSLSKTGLSQVTLVFEDGVDVYRV 106
Cdd:NF033617 22 GLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQFRLGTDLDVA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 107 RQLVSERLAGAAKELPAGltpMLAPITsglsdifyyvvdYAENAPDKPAT-----RAEQLRELQLIH--DFVIKPQLRTV 179
Cdd:NF033617 102 LSEVQAAINAAQSLLPSE---APDPPV------------YRKANSADTPImyiglTSEEMPRGQLTDyaERVLAPKLSQI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 180 RGVVEVNASGGYEKQIIVQPRPDALLAAGVTFHELAEIVGENVENAGGGAVQIGGEQLSIRADSRVRSTEEISRLPLKFR 259
Cdd:NF033617 167 NGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 260 GAGiAPLLVSDVADVVVGSSLRTGTATHNGREALLGAALMLTGENARLVARRVADKLAEIQPRLPAGVTLTTVYDRTDLV 339
Cdd:NF033617 247 DNG-APVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFI 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 340 DRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMSLGA--VDFGLIIDGAVVMV 417
Cdd:NF033617 326 RASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMAlvLAIGLVVDDAIVVV 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 418 ENIVRRIgarqhavgrdltrEERLHTVLAA---AKEVGrptfFGVAIITL----VYVPILSLTGIEGKMFEPMALTVIFA 490
Cdd:NF033617 406 ENIHRHI-------------EEGESPLEAAlkgAREIG----FTVIAMTLtlvaVYLPILFMGGLTGRLFREFAVTLAGA 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 491 LIGALILTLTLMPVLCSFGLR-----GRVAEGDGWLVRALKRLYVPVLARALRWRWAVVGGGLALCGLAAALFGRLGAEF 565
Cdd:NF033617 469 VIISGIVALTLTPMMCSRLLKanekpGRFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKEL 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 566 VPQLDEGSFATFMIRTNSIGLEA-SLAMQERGERLLreKFPLVTHTFSRIGTAEVAtdpmGVNVADTYIFYRPFAEwpRD 644
Cdd:NF033617 549 APSEDRGVIFGMIQAPQSISLDYmSAKMRDVEKILS--SDPEVQSLTSFNGVGGNP----GDNTGFGIINLKPWDE--RD 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 645 EhgdgpTKDEVADAMAEILGtHLPGeAHLFSQPiemrFNEILEGTRADIAVKVF---GDDFERIEAIASEVREILEQVPG 721
Cdd:NF033617 621 V-----SAQEIIDRLRPKLA-KVPG-MDLFLFP----LQDLPGGAGSSLPQYQVtltPSDYDSLFTWAEKLKEKLRKSPQ 689
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 722 AADVEFDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLRSALEELKHLPLR 801
Cdd:NF033617 690 FADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVR 769
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 802 laHADG-VITLGDVAEFVVTEKVNAIARESGQRRAAIMVNLRGRDVESFVHEAQARVrAQVELPAGYAIEFGGQFKNLQE 880
Cdd:NF033617 770 --SNDGkLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQA-AKELLPSGISGSFQGAARAFQE 846
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 881 ARGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVAVLNGLMLVST 960
Cdd:NF033617 847 EGSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEF 926
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 501344150 961 FNQL-REEGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTLVMLPVLY 1037
Cdd:NF033617 927 ANELqRHQGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVY 1004
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
27-1037 |
6.66e-72 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 259.40 E-value: 6.66e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 27 GSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMTELRSLSKTGLSQVTLVFEDGVDVYRV 106
Cdd:PRK09577 23 GIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSAGQASLSLTFKQGVNADLA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 107 RQLVSERLAGAAKELPAGLTPMLAPITSGLSDIFYYVVDYAENApdkpATRAEQLRELQLIHdfvIKPQLRTVRGVVEVN 186
Cdd:PRK09577 103 AVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDG----RLTGVELGEYASAN---VLQALRRVEGVGKVQ 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 187 aSGGYEKQIIVQPRPDALLAAGVTFHELAEIVgeNVENAGGGAVQIGGEQL--------SIRADSRVRSTEEISRLPLKF 258
Cdd:PRK09577 176 -FWGAEYAMRIWPDPVKLAALGLTASDIASAV--RAHNARVTIGDIGRSAVpdsapiaaTVFADAPLKTPEDFGAIALRA 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 259 RGAGIApLLVSDVADVVVGSSLRTGTATHNGREALLGAALMLTGENARLVARRVADKLAEIQPRLPAGVTLTTVYDRTDL 338
Cdd:PRK09577 253 RADGSA-LYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPGVKYQIPYETSSF 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 339 VDRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMSL-GAV-DFGLIIDGAVVM 416
Cdd:PRK09577 332 VRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMfGMVlAIGILVDDAIVV 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 417 VENIVRrigarqhavgrdLTREERL---HTVLAAAKEVGRPTFFGVAIITLVYVPILSLTGIEGKMFEPMALTVIFALIG 493
Cdd:PRK09577 412 VENVER------------LMVEEGLspyDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 494 ALILTLTLMPVLCSFGLRgRVAEGD-------GWLVRALKRL-------YVPVLARALRWrwavVGGGLALCGLAAALFG 559
Cdd:PRK09577 480 SAFLALSLTPALCATLLK-PVDGDHhekrgffGWFNRFVARStqryatrVGAILKRPLRW----LVVYGALTAAAALLFT 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 560 RLGAEFVPQLDEGSFATFMIRTNSIGLEASLAMQERGERLLREKFPlVTHTFSRIGTAEVATDPMGVNVADTyifyrpFA 639
Cdd:PRK09577 555 RLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEP-VAYTFALGGFNLYGEGPNGGMIFVT------LK 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 640 EWPRDEHGDGPTKDEVADAMAEILGT--------HLPGEAHLFSQP-IEMRFNEilegtRADIAVKVFGDDFERIEAIAS 710
Cdd:PRK09577 628 DWKERKAARDHVQAIVARINERFAGTpnttvfamNSPALPDLGSTSgFDFRLQD-----RGGLGYAAFVAAREQLLAEGA 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 711 evreileQVPGAADVEFDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLRS 790
Cdd:PRK09577 703 -------KDPALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRL 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 791 ALEELKHLPLRLAHADgVITLGDVAEFVVTEKVNAIARESGQrrAAIMVNLRGRDVESFVHEAQARVRAQVELPAGYAIE 870
Cdd:PRK09577 776 DPDDVKKLRVRNAQGE-MVPLAAFATLHWTLGPPQLTRYNGY--PSFTINGSAAPGHSSGEAMAAIERIAATLPAGIGYA 852
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 871 FGGQFKNLQEARGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVA 950
Cdd:PRK09577 853 WSGQSFEERLSGAQAPMLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLS 932
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 951 VLNGLMLVSTFNQLREEGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTL 1030
Cdd:PRK09577 933 AKNAILIVEVAKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAV 1012
|
....*..
gi 501344150 1031 VMLPVLY 1037
Cdd:PRK09577 1013 FLVPLFF 1019
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1050 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1376.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 1 MIDRILEFALRQRVFVLLGALLLVVVGSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMT 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 81 ELRSLSKTGLSQVTLVFEDGVDVYRVRQLVSERLAGAAKELPAGLTPMLAPITSGLSDIFYYVVDyaenaPDKPATRAEQ 160
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLE-----SDPGKYSLME 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 161 LRELQlihDFVIKPQLRTVRGVVEVNASGGYEKQIIVQPRPDALLAAGVTFHELAEIVGENVENAGGGAVQIGGEQLSIR 240
Cdd:COG3696 156 LRTLQ---DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 241 ADSRVRSTEEISRLPLKFRGAgiAPLLVSDVADVVVGSSLRTGTATHNGR-EALLGAALMLTGENARLVARRVADKLAEI 319
Cdd:COG3696 233 GIGLIRSLEDIENIVVKTRNG--TPVLLRDVAEVRIGPAPRRGAATLNGEgEVVGGIVLMLKGENALEVIEAVKAKLAEL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 320 QPRLPAGVTLTTVYDRTDLVDRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLM 399
Cdd:COG3696 311 KPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLM 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 400 SLG--AVDFGLIIDGAVVMVENIVRRIGARQHAvgrdLTREERLHTVLAAAKEVGRPTFFGVAIITLVYVPILSLTGIEG 477
Cdd:COG3696 391 SLGglAIDFGIIVDGAVVMVENILRRLEENRAA----GTPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEG 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 478 KMFEPMALTVIFALIGALILTLTLMPVLCSFGLRGRVAEGDGWLVRALKRLYVPVLARALRWRWAVVGGGLALCGLAAAL 557
Cdd:COG3696 467 KLFRPMALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALAL 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 558 FGRLGAEFVPQLDEGSFATFMIRTNSIGLEASLAMQERGERLLREkFPLVTHTFSRIGTAEVATDPMGVNVADTYIFYRP 637
Cdd:COG3696 547 FPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKS-FPEVESVVSRTGRAEDATDPMGVNMSETFVILKP 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 638 FAEWPrdehgDGPTKDEVADAMAEILGThLPGEAHLFSQPIEMRFNEILEGTRADIAVKVFGDDFERIEAIASEVREILE 717
Cdd:COG3696 626 RSEWR-----SGRTKEELIAEMREALEQ-IPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLK 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 718 QVPGAADVEFDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLRSALEELKH 797
Cdd:COG3696 700 TVPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRN 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 798 LPLRLAHAdGVITLGDVAEFVVTEKVNAIARESGQRRAAIMVNLRGRDVESFVHEAQARVRAQVELPAGYAIEFGGQFKN 877
Cdd:COG3696 780 LPIPTPSG-AQVPLSQVADIEVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFEN 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 878 LQEARGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVAVLNGLML 957
Cdd:COG3696 859 LQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVL 938
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 958 VSTFNQLREEGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTLVMLPVLY 1037
Cdd:COG3696 939 VSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALY 1018
|
1050
....*....|...
gi 501344150 1038 EWSEARLARRRAE 1050
Cdd:COG3696 1019 LLFGRRRLRRAAA 1031
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1054 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 1105.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 1 MIDRILEFALRQRVFVLLGALLLVVVGSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMT 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 81 ELRSLSKTGLSQVTLVFEDGVDVYRVRQLVSERLAGAAKELPAGLTPMLAPITSGLSDIFYYVVDYAENAPDKPAtRAEQ 160
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGARKKDG-GAYT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 161 LRELQLIHDFVIKPQLRTVRGVVEVNASGGYEKQIIVQPRPDALLAAGVTFHELAEIVGENVENAGGGAVQIGGEQLSIR 240
Cdd:TIGR00914 160 LTDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 241 ADSRVRSTEEISRLPLKfRGAGIaPLLVSDVADVVVGSSLRTGTATHNGREALLGAALMLTGENARLVARRVADKLAEIQ 320
Cdd:TIGR00914 240 APGQVQSMDDIRNIVIA-TGEGV-PIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETIN 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 321 PRLPAGVTLTTVYDRTDLVDRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMS 400
Cdd:TIGR00914 318 KTLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMS 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 401 LGAVDFGLIIDGAVVMVENIVRRIGARQHAVGRDLTREERLHTVLAAAKEVGRPTFFGVAIITLVYVPILSLTGIEGKMF 480
Cdd:TIGR00914 398 LGALDFGLIVDGAVVIVENAHRRLAEAQHHHGRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMF 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 481 EPMALTVIFALIGALILTLTLMPVLCSFGLRGRVAEGDGWLVRALKRLYVPVLARALRWRWAVVGGGLALCGLAAALFGR 560
Cdd:TIGR00914 478 HPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASR 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 561 LGAEFVPQLDEGSFATFMIRTNSIGLEASLAMQERGERLLReKFPLVTHTFSRIGTAEVATDPMGVNVADTYIFYRPFAE 640
Cdd:TIGR00914 558 VGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIK-SFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPESQ 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 641 WPrdehgdgPTKDEVADAMAEIL--GTHLPGEAHLFSQPIEMRFNEILEGTRADIAVKVFGDDFERIEAIASEVREILEQ 718
Cdd:TIGR00914 637 WP-------EGKKTKEDLIEEIQeaTVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKG 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 719 VPGAADVEFDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLRSALEELKHL 798
Cdd:TIGR00914 710 VPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQL 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 799 PLRLAHADGV----ITLGDVAEFVVTEKVNAIARESGQRRAAIMVNLRGRDVESFVHEAQARVRAQVELPAGYAIEFGGQ 874
Cdd:TIGR00914 790 PIPLPLSEDArkqfIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQ 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 875 FKNLQEARGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVAVLNG 954
Cdd:TIGR00914 870 FEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNG 949
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 955 LMLVSTFNQLREEGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTLVMLP 1034
Cdd:TIGR00914 950 LVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLP 1029
|
1050 1060
....*....|....*....|
gi 501344150 1035 VLYEWSEARLARRRAEGKTL 1054
Cdd:TIGR00914 1030 ALYRLVHRRRHKGRKEHEPL 1049
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1037 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 866.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 5 ILEFALRQRVFVLLGALLLVVVGSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMTELRS 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 85 LSKTGLSQVTLVFEDGVDVYRVRQLVSERLAGAAKELPAGL-TPMLAPITSGLSDIFYYVVDyaenaPDKPATRAEQLRE 163
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVqRPGISVIKTSLGPIMVLAVT-----SPDGSYTQTDLRD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 164 LQlihDFVIKPQLRTVRGVVEVNASGGYEKQIIVQPRPDALLAAGVTFHELAEIVGENVENAGGGAVQIGGEQLSIRADS 243
Cdd:pfam00873 156 YA---DTNIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 244 RVRSTEEISRLPLKfrGAGIAPLLVSDVADVVVGSSLRTGTATHNGREALLGAALMLTGENARLVARRVADKLAEIQPRL 323
Cdd:pfam00873 233 QLQSAEDFEKIIVK--NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTF 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 324 PAGVTLTTVYDRTDLVDRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMSLGA 403
Cdd:pfam00873 311 PQGVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGG 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 404 VDF--GLIIDGAVVMVENIVRRIGARQhavgrdltrEERLHTVLAAAKEVGRPTFFGVAIITLVYVPILSLTGIEGKMFE 481
Cdd:pfam00873 391 LVLaiGLVVDDAIVVVENIERVLEENG---------LKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFR 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 482 PMALTVIFALIGALILTLTLMPVLCSFGLRGRVAEGDGW-------LVRALKRLYVPVLARALRWRWAVVGGGLALCGLA 554
Cdd:pfam00873 462 QFAITIVLAILLSVLVALTLTPALCATLLKPRREPKHGGffrwfnrMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGS 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 555 AALFGRLGAEFVPQLDEGSFATFMIRTNSIGLEASLAMQERGERLLREkFPLVTHTFSRIGTAEvATDPMGVNVADTYIF 634
Cdd:pfam00873 542 VWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKE-KPEVESVFAVTGFAF-SGDNNGPNSGDAFIS 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 635 YRPFAEWPRDEHgdgpTKDEVADAMAEILGThLPGEAHLFSQPIEMRFNEILEGTRADIAVKVFGDDFERIEAIASEVRE 714
Cdd:pfam00873 620 LKPWKERPGPEK----SVQALIERLRKALKQ-IPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILA 694
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 715 ILEQVPGAADVEFDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLRSALEE 794
Cdd:pfam00873 695 ALAQLPGLSDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPED 774
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 795 LKHLPLRLAHaDGVITLGDVAEFVVTEKVNAIARESGQRRAAIMVNLRGRDVESFVHEAQARVRAQVELPAGYAIEFGGQ 874
Cdd:pfam00873 775 IGQLYVRNPY-GKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQ 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 875 FKNLQEARGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVAVLNG 954
Cdd:pfam00873 854 FEQEQLAGNSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNA 933
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 955 LMLVSTFNQLRE-EGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTLVML 1033
Cdd:pfam00873 934 ILMVEFANELREqEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVV 1013
|
....
gi 501344150 1034 PVLY 1037
Cdd:pfam00873 1014 PVFY 1017
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
27-1048 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 705.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 27 GSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMTELRSLSKTGLSQVTLVFEDGVDVYRV 106
Cdd:COG0841 25 GLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITSTSSEGSSSITVEFELGTDIDEA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 107 RQLVSERLAGAAKELPAGLT-PMLAPITSGLSDIFYYVVdYAENAPdkpatraeqLRELQLIHDFVIKPQLRTVRGVVEV 185
Cdd:COG0841 105 LVDVQNAVDRARSDLPEDVEpPGVTKVNPSDFPVMVLAL-SSDDLD---------ELELSDYAERNIKDRLERVPGVGQV 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 186 NASGGYEKQIIVQPRPDALLAAGVTFHELAEIVGENVENAGGGAVQIGGEQLSIRADSRVRSTEEISRLPLKFRGAgiAP 265
Cdd:COG0841 175 QIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEEFENIVIRTNDG--SV 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 266 LLVSDVADVVVGSSLRTGTATHNGREALLGAALMLTGENARLVARRVADKLAEIQPRLPAGVTLTTVYDRTDLVDRTIRT 345
Cdd:COG0841 253 VRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPEGVELTIVYDQSEFIRASIEE 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 346 VRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMSLGAVDF--GLIIDGAVVMVENIVRR 423
Cdd:COG0841 333 VVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLaiGIVVDDAIVVVENIERH 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 424 IgaRQHavgrdltrEERLHTVLAAAKEVGRPTFFGVAIITLVYVPILSLTGIEGKMFEPMALTVIFALIGALILTLTLMP 503
Cdd:COG0841 413 M--EEG--------LSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALTLTP 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 504 VLCSFGLRGRVAEGDGWLVRA-------LKRLYVPVLARALRWRWAVVGGGLALCGLAAALFGRLGAEFVPQLDEGSFAT 576
Cdd:COG0841 483 ALCARLLKPHPKGKKGRFFRAfnrgfdrLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIV 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 577 FMIRTNSIGLEASLAMQERGERLLREKfPLVTHTFSRIGTAEVATdpmGVNVADTYIFYRPFAEwpRDEhgdgpTKDEVA 656
Cdd:COG0841 563 SVQLPPGTSLERTEAVVRQVEEILLEV-PEVESVFSVVGFSGGGS---GSNSGTIFVTLKPWDE--RDR-----SADEII 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 657 DAMAEILGtHLPGeAHLFSQPIEMRFNeileGTRADIAVKVFGDDFERIEAIASEVREILEQVPGAADVEFDALGKAPLL 736
Cdd:COG0841 632 ARLREKLA-KIPG-ARVFVFQPPAGGL----GSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPEL 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 737 EIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLRSALEELKHLPLRLAhADGVITLGDVAE 816
Cdd:COG0841 706 QLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTP-DGEMVPLSSVAT 784
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 817 FVVTEKVNAIARESGQRRAAIMVNL-RGRDVESFVHEAQARVrAQVELPAGYAIEFGGQFKNLQEARGRLAIIVPLALAV 895
Cdd:COG0841 785 IEEGTGPSSINRYNGQRSVTVSANLaPGVSLGEALAAIEELA-AELKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLL 863
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 896 IFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVAVLNGLMLVSTFNQLREEGWNVAEAV 975
Cdd:COG0841 864 VYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAI 943
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 501344150 976 REGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTLVMLPVLYEWSEaRLARRR 1048
Cdd:COG0841 944 LEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLD-RLRRRL 1015
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
27-1037 |
6.05e-133 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 427.90 E-value: 6.05e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 27 GSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMTELRSLSKTGLSQVTLVFEDGVDVYRV 106
Cdd:NF033617 22 GLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQFRLGTDLDVA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 107 RQLVSERLAGAAKELPAGltpMLAPITsglsdifyyvvdYAENAPDKPAT-----RAEQLRELQLIH--DFVIKPQLRTV 179
Cdd:NF033617 102 LSEVQAAINAAQSLLPSE---APDPPV------------YRKANSADTPImyiglTSEEMPRGQLTDyaERVLAPKLSQI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 180 RGVVEVNASGGYEKQIIVQPRPDALLAAGVTFHELAEIVGENVENAGGGAVQIGGEQLSIRADSRVRSTEEISRLPLKFR 259
Cdd:NF033617 167 NGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 260 GAGiAPLLVSDVADVVVGSSLRTGTATHNGREALLGAALMLTGENARLVARRVADKLAEIQPRLPAGVTLTTVYDRTDLV 339
Cdd:NF033617 247 DNG-APVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFI 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 340 DRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMSLGA--VDFGLIIDGAVVMV 417
Cdd:NF033617 326 RASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMAlvLAIGLVVDDAIVVV 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 418 ENIVRRIgarqhavgrdltrEERLHTVLAA---AKEVGrptfFGVAIITL----VYVPILSLTGIEGKMFEPMALTVIFA 490
Cdd:NF033617 406 ENIHRHI-------------EEGESPLEAAlkgAREIG----FTVIAMTLtlvaVYLPILFMGGLTGRLFREFAVTLAGA 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 491 LIGALILTLTLMPVLCSFGLR-----GRVAEGDGWLVRALKRLYVPVLARALRWRWAVVGGGLALCGLAAALFGRLGAEF 565
Cdd:NF033617 469 VIISGIVALTLTPMMCSRLLKanekpGRFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKEL 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 566 VPQLDEGSFATFMIRTNSIGLEA-SLAMQERGERLLreKFPLVTHTFSRIGTAEVAtdpmGVNVADTYIFYRPFAEwpRD 644
Cdd:NF033617 549 APSEDRGVIFGMIQAPQSISLDYmSAKMRDVEKILS--SDPEVQSLTSFNGVGGNP----GDNTGFGIINLKPWDE--RD 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 645 EhgdgpTKDEVADAMAEILGtHLPGeAHLFSQPiemrFNEILEGTRADIAVKVF---GDDFERIEAIASEVREILEQVPG 721
Cdd:NF033617 621 V-----SAQEIIDRLRPKLA-KVPG-MDLFLFP----LQDLPGGAGSSLPQYQVtltPSDYDSLFTWAEKLKEKLRKSPQ 689
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 722 AADVEFDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLRSALEELKHLPLR 801
Cdd:NF033617 690 FADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVR 769
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 802 laHADG-VITLGDVAEFVVTEKVNAIARESGQRRAAIMVNLRGRDVESFVHEAQARVrAQVELPAGYAIEFGGQFKNLQE 880
Cdd:NF033617 770 --SNDGkLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQA-AKELLPSGISGSFQGAARAFQE 846
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 881 ARGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVAVLNGLMLVST 960
Cdd:NF033617 847 EGSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEF 926
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 501344150 961 FNQL-REEGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTLVMLPVLY 1037
Cdd:NF033617 927 ANELqRHQGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVY 1004
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
27-1037 |
7.40e-90 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 310.89 E-value: 7.40e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 27 GSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMTELRSLS-KTGLSQVTLVFEDGVDVYR 105
Cdd:TIGR00915 23 GTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSSSdSDGSMTITLTFEQGTDPDI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 106 VRQLVSERLAGAAKELPAGLTPMLAPITSGlSDIFYYVVDYAEnapDKPATRAEQLrelqliHDFV---IKPQLRTVRGV 182
Cdd:TIGR00915 103 AQVQVQNKLQLATPLLPQEVQRQGVRVEKA-SSNFLMVIGLVS---DDGSMTKEDL------SDYAasnMVDPLSRLEGV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 183 VEVNASGG-YEKQIIVQprPDALLAAGVTFHELAEIVGEnvENAGGGAVQIGGE--------QLSIRADSRVRSTEEISR 253
Cdd:TIGR00915 173 GDVQLFGSqYAMRIWLD--PAKLNSYQLTPADVISAISA--QNAQISAGQLGGLpavpgqqlNATIIAQTRLQTPEQFEN 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 254 LPLKFRGAGiAPLLVSDVADVVVGSSLRTGTATHNGREAlLGAALML-TGENARLVARRVADKLAEIQPRLPAGVTLTTV 332
Cdd:TIGR00915 249 ILLKVNTDG-SQVRLKDVARVELGGENYSISARFNGKPA-SGLAIKLaTGANALDTAKAVKAELAVLEPFFPQGMKYVYP 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 333 YDRTDLVDRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFL--FAItgMVRFGVSGNLMSLGA--VDFGL 408
Cdd:TIGR00915 327 YDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLgtFAV--LAAFGFSINTLTMFAmvLAIGL 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 409 IIDGAVVMVENIVRrigarqhavgrdLTREERLHTVLAAAKEVGRPTFFGVAI---ITLVYVPILSLTGIEGKMFEPMAL 485
Cdd:TIGR00915 405 LVDDAIVVVENVER------------VMAEEGLPPKEATRKSMGQIQGALVGIamvLSAVFVPMAFFGGSTGAIYRQFSI 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 486 TVIFALIGALILTLTLMPVLCSFGLR--------GRVAEGDGWLVRALKRL---YVPVLARALRWRWAVVGGGLALCGLA 554
Cdd:TIGR00915 473 TIVSAMALSVLVALILTPALCATMLKpiekgehhEKKGGFFGWFNRMFDSSthgYENGVGKILRRRGRYLLVYVLLVGGM 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 555 AALFGRLGAEFVPQLDEGSFATfMIRT--NSIGLEASLAMQERGERLLREKFPLVTHTFSRIGTAEVATdpmGVNVADTY 632
Cdd:TIGR00915 553 VFLFVRLPTSFLPDEDQGVFMT-IVQLpaGATAERTQAVLAQVTKYLLAKEKANVESVFTVNGFSFAGR---GQNMGMAF 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 633 IFYRPFAEwprdEHGDGPTKDEVADAMAEILGTHLPGEAHLFSQPiemrfnEILE-GTRAdiavkvfGDDFERI------ 705
Cdd:TIGR00915 629 IRLKDWEE----RTGKENSVFAIAGRATGHFMQIKDAMVIAFVPP------AILElGNAT-------GFDFFLQdraglg 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 706 -EAIASEVREILE---QVPGAADVEFDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPIL 781
Cdd:TIGR00915 692 hEALLQARNQLLGlaaQNPALTRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVY 771
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 782 VRLPERLRSALEELKHLPLRLAHADGVitlgDVAEFVVTEKVNA---IARESGQRRAAIMvnlrGRDVESF-VHEAQARV 857
Cdd:TIGR00915 772 VQAEEDARMSPEDINKWYVRNASGEMV----PFSAFATVRWEYGspqLERYNGLPSMEIL----GSAAPGVsTGQAMAAM 843
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 858 RAQV-ELPAGYAIEFGGQFKNLQEARGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFS 936
Cdd:TIGR00915 844 EAIAqKLPPGFGFSWTGMSYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSND 923
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 937 ISAGIGFIALSGVAVLNGLMLVSTFNQLREEGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLAT 1016
Cdd:TIGR00915 924 VYFQVGLLTTIGLSAKNAILIVEFAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGT 1003
|
1050 1060
....*....|....*....|.
gi 501344150 1017 VVIGGIVTSTFLTLVMLPVLY 1037
Cdd:TIGR00915 1004 GVFGGMVTATVLAIFFVPLFY 1024
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
27-1037 |
6.66e-72 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 259.40 E-value: 6.66e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 27 GSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMTELRSLSKTGLSQVTLVFEDGVDVYRV 106
Cdd:PRK09577 23 GIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSAGQASLSLTFKQGVNADLA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 107 RQLVSERLAGAAKELPAGLTPMLAPITSGLSDIFYYVVDYAENApdkpATRAEQLRELQLIHdfvIKPQLRTVRGVVEVN 186
Cdd:PRK09577 103 AVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDG----RLTGVELGEYASAN---VLQALRRVEGVGKVQ 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 187 aSGGYEKQIIVQPRPDALLAAGVTFHELAEIVgeNVENAGGGAVQIGGEQL--------SIRADSRVRSTEEISRLPLKF 258
Cdd:PRK09577 176 -FWGAEYAMRIWPDPVKLAALGLTASDIASAV--RAHNARVTIGDIGRSAVpdsapiaaTVFADAPLKTPEDFGAIALRA 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 259 RGAGIApLLVSDVADVVVGSSLRTGTATHNGREALLGAALMLTGENARLVARRVADKLAEIQPRLPAGVTLTTVYDRTDL 338
Cdd:PRK09577 253 RADGSA-LYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPGVKYQIPYETSSF 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 339 VDRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMSL-GAV-DFGLIIDGAVVM 416
Cdd:PRK09577 332 VRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMfGMVlAIGILVDDAIVV 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 417 VENIVRrigarqhavgrdLTREERL---HTVLAAAKEVGRPTFFGVAIITLVYVPILSLTGIEGKMFEPMALTVIFALIG 493
Cdd:PRK09577 412 VENVER------------LMVEEGLspyDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 494 ALILTLTLMPVLCSFGLRgRVAEGD-------GWLVRALKRL-------YVPVLARALRWrwavVGGGLALCGLAAALFG 559
Cdd:PRK09577 480 SAFLALSLTPALCATLLK-PVDGDHhekrgffGWFNRFVARStqryatrVGAILKRPLRW----LVVYGALTAAAALLFT 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 560 RLGAEFVPQLDEGSFATFMIRTNSIGLEASLAMQERGERLLREKFPlVTHTFSRIGTAEVATDPMGVNVADTyifyrpFA 639
Cdd:PRK09577 555 RLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEP-VAYTFALGGFNLYGEGPNGGMIFVT------LK 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 640 EWPRDEHGDGPTKDEVADAMAEILGT--------HLPGEAHLFSQP-IEMRFNEilegtRADIAVKVFGDDFERIEAIAS 710
Cdd:PRK09577 628 DWKERKAARDHVQAIVARINERFAGTpnttvfamNSPALPDLGSTSgFDFRLQD-----RGGLGYAAFVAAREQLLAEGA 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 711 evreileQVPGAADVEFDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLRS 790
Cdd:PRK09577 703 -------KDPALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRL 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 791 ALEELKHLPLRLAHADgVITLGDVAEFVVTEKVNAIARESGQrrAAIMVNLRGRDVESFVHEAQARVRAQVELPAGYAIE 870
Cdd:PRK09577 776 DPDDVKKLRVRNAQGE-MVPLAAFATLHWTLGPPQLTRYNGY--PSFTINGSAAPGHSSGEAMAAIERIAATLPAGIGYA 852
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 871 FGGQFKNLQEARGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVA 950
Cdd:PRK09577 853 WSGQSFEERLSGAQAPMLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLS 932
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 951 VLNGLMLVSTFNQLREEGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTL 1030
Cdd:PRK09577 933 AKNAILIVEVAKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAV 1012
|
....*..
gi 501344150 1031 VMLPVLY 1037
Cdd:PRK09577 1013 FLVPLFF 1019
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
27-1052 |
2.47e-68 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 248.98 E-value: 2.47e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 27 GSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMTELRSLSK-TGLSQVTLVFEDGVDVYR 105
Cdd:PRK10555 23 GTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSgTGQASVTLSFKAGTDPDE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 106 VRQLVSERLAGAAKELPAGLTPMLAPIT-SGLSDIFYYVVDYAENAPDKpatraeqlrelQLIHDFV---IKPQLRTVRG 181
Cdd:PRK10555 103 AVQQVQNQLQSAMRKLPQAVQNQGVTVRkTGDTNILTIAFVSTDGSMDK-----------QDIADYVasnIQDPLSRVNG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 182 VVEVNASGG-YEKQIIVQPrpDALLAAGVTFHELAE-IVGENVENAGGgavQIGGE--------QLSIRADSRVRSTEEI 251
Cdd:PRK10555 172 VGDIDAYGSqYSMRIWLDP--AKLNSFQMTTKDVTDaIESQNAQIAVG---QLGGTpsvdkqalNATINAQSLLQTPEQF 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 252 SRLPLKFRGAGIAPLLvSDVADVVVGSSLRTGTATHNGREAL-LGAALMlTGENARLVARRVADKLAEIQPRLPAGVTLT 330
Cdd:PRK10555 247 RDITLRVNQDGSEVTL-GDVATVELGAEKYDYLSRFNGKPASgLGVKLA-SGANEMATAKLVLNRLDELAQYFPHGLEYK 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 331 TVYDRTDLVDRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMSLGAV--DFGL 408
Cdd:PRK10555 325 VAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMvlAIGL 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 409 IIDGAVVMVENiVRRIGARQHAVGRDLTReerlhtvlaaaKEVG--RPTFFGVA-IITLVYVPILSLTGIEGKMFEPMAL 485
Cdd:PRK10555 405 LVDDAIVVVEN-VERIMSEEGLTPREATR-----------KSMGqiQGALVGIAmVLSAVFVPMAFFGGTTGAIYRQFSI 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 486 TVIFALIGALILTLTLMPVLCSFGLRgRVAEGD--------GWLVRAL-------KRLYVPVLARALRWrwavVGGGLAL 550
Cdd:PRK10555 473 TIVSAMVLSVLVAMILTPALCATLLK-PLKKGEhhgqkgffGWFNRMFnrnaeryEKGVAKILHRSLRW----ILIYVLL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 551 CGLAAALFGRLGAEFVPQLDEGSFATFMIRTNSIGLEASLAMQERGER-LLREKFPLVTHTFSRIGTAEVATdpmGVNVA 629
Cdd:PRK10555 548 LGGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKyYFTHEKDNVMSVFATVGSGPGGN---GQNVA 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 630 DTYIFYRPFAEWPRDEHGDGPTKDEVADAMAEIlgthlpGEAHLF-SQPIEMRFneilEGTRADIAVKV---FGDDFERI 705
Cdd:PRK10555 625 RMFIRLKDWDERDSKTGTSFAIIERATKAFNKI------KEARVIaSSPPAISG----LGSSAGFDMELqdhAGAGHDAL 694
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 706 EAIASEVREILEQVPGAADVEFDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLP 785
Cdd:PRK10555 695 MAARNQLLALAAKNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAA 774
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 786 ERLRSALEELKHLPLRLAHadgvitlGDVAEFvvtekvNAIARESGQRRAAIMVNLRGRDVESFVHEAQARVRAQV---- 861
Cdd:PRK10555 775 APYRMLPDDINLWYVRNKD-------GGMVPF------SAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTamdi 841
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 862 ------ELPAGYAIEFGGQfkNLQEargRLA-----IIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALAL 930
Cdd:PRK10555 842 meslvkQLPNGFGLEWTAM--SYQE---RLSgaqapALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWM 916
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 931 RGLPFSISAGIGFIALSGVAVLNGLMLVSTFNQLREEGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEV 1010
Cdd:PRK10555 917 RGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGS 996
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|..
gi 501344150 1011 QRPLATVVIGGIVTSTFLTLVMLPVLYEwsearLARRRAEGK 1052
Cdd:PRK10555 997 QHAVGTGVMGGMISATILAIFFVPLFFV-----LVRRRFPLK 1033
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
27-1052 |
6.39e-66 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 241.73 E-value: 6.39e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 27 GSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMTELRSLS-KTGLSQVTLVFEDGVDVYR 105
Cdd:PRK15127 23 GGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdSTGTVQITLTFESGTDADI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 106 VRQLVSERLAGAAKELPAGLTPMLAPITSGlSDIFYYVVDYAEnapDKPATRAEQlrelqlIHDFV---IKPQLRTVRGV 182
Cdd:PRK15127 103 AQVQVQNKLQLAMPLLPQEVQQQGVSVEKS-SSSFLMVVGVIN---TDGTMTQED------ISDYVaanMKDPISRTSGV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 183 VEVNASGG-YEKQIIVQPR--------PDALLAAgvtfhelaeIVGENVENAGG---GAVQIGGEQL--SIRADSRVRST 248
Cdd:PRK15127 173 GDVQLFGSqYAMRIWMNPNelnkfqltPVDVINA---------IKAQNAQVAAGqlgGTPPVKGQQLnaSIIAQTRLTST 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 249 EEISRLPLKFRGAGiAPLLVSDVADVVVGSSLRTGTATHNGREALLGAALMLTGENARLVARRVADKLAEIQPRLPAGVT 328
Cdd:PRK15127 244 EEFGKILLKVNQDG-SRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 329 LTTVYDRTDLVDRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMSL-GAV-DF 406
Cdd:PRK15127 323 IVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMfGMVlAI 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 407 GLIIDGAVVMVENIVRrigarqhavgrdLTREERLHTVLAAAKEVG--RPTFFGVA-IITLVYVPILSLTGIEGKMFEPM 483
Cdd:PRK15127 403 GLLVDDAIVVVENVER------------VMAEEGLPPKEATRKSMGqiQGALVGIAmVLSAVFVPMAFFGGSTGAIYRQF 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 484 ALTVIFALIGALILTLTLMPVLCSFGLRgRVAEGD---------GWLVRALKRL---YVPVLARALRWRWAVVGGGLALC 551
Cdd:PRK15127 471 SITIVSAMALSVLVALILTPALCATMLK-PIAKGDhgegkkgffGWFNRMFEKSthhYTDSVGNILRSTGRYLVLYLIIV 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 552 GLAAALFGRLGAEFVPQLDEGSFATFmirtnsIGLEASlAMQERGERLLREkfplVTHTF---------SRIGTAEVATD 622
Cdd:PRK15127 550 VGMAYLFVRLPSSFLPDEDQGVFLTM------VQLPAG-ATQERTQKVLNE----VTDYYltkeknnveSVFAVNGFGFA 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 623 PMGVNVADTYIFYRPFAEWPRDEHGDGPTKDEVADAMAEIlgthlpGEAHLFSqpiemrFN--EILE-GTRAdiavkvfG 699
Cdd:PRK15127 619 GRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQI------KDAMVFA------FNlpAIVElGTAT-------G 679
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 700 DDFERI-------EAIASEVREILEQVPGAAD----VEFDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEV 768
Cdd:PRK15127 680 FDFELIdqaglghEKLTQARNQLLGEAAKHPDmlvgVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYV 759
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 769 GTIVDGNRRYPILVRLPERLRSALEELKHLPLRlahadgvitlGDVAEFVVTEKVNAIARESGQRRAAIMVNLRGRDVES 848
Cdd:PRK15127 760 NDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVR----------AADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILG 829
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 849 FVHEAQARVRAQ-------VELPAGYAIEFGGQFKNLQEARGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAI 921
Cdd:PRK15127 830 QAAPGKSTGEAMelmeelaSKLPTGVGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGV 909
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 922 TGGVVALALRGLPFSISAGIGFIALSGVAVLNGLMLVSTFNQLRE-EGWNVAEAVREGALTRLRPVLMTALVASLGFLPM 1000
Cdd:PRK15127 910 IGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDkEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPL 989
|
1050 1060 1070 1080 1090
....*....|....*....|....*....|....*....|....*....|..
gi 501344150 1001 ALSNGAGAEVQRPLATVVIGGIVTSTFLTLVMLPVLYEWSEARLARRRAEGK 1052
Cdd:PRK15127 990 VISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDIE 1041
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
27-1053 |
9.12e-65 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 237.81 E-value: 9.12e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 27 GSWAALRLPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMTELRSLSKTGLSQVTLVFEDGVDVYRv 106
Cdd:PRK09579 25 GFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQNFSIISIYARIGADSDR- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 107 rqLVSERLAGAAK---ELPAGLT-PMLAPITSGLSDIFYYvvdyaenapdkpATRAEQLRELQlIHDF---VIKPQLRTV 179
Cdd:PRK09579 104 --LFTELLAKANEvknQLPQDAEdPVLSKEAADASALMYI------------SFYSEEMSNPQ-ITDYlsrVIQPKLATL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 180 RGVVEVNASGGYEKQIIVQPRPDALLAAGVTFHELAEIVGE-NVENAGGgavQIGGEQL--SIRADSRVRSTEEISRLPL 256
Cdd:PRK09579 169 PGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRyNFLSAAG---EVKGEYVvtSINASTELKSAEAFAAIPV 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 257 KFrgAGIAPLLVSDVADVVVGSSLRTGTATHNGREALLGAALMLTGENARLVARRVADKLAEIQPRLPAGVTLTTVYDRT 336
Cdd:PRK09579 246 KT--SGDSRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIAYDAT 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 337 DLVDRTIRTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMSLGA--VDFGLIIDGAV 414
Cdd:PRK09579 324 LFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAmvLAIGLVVDDAI 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 415 VMVENIVRRIGARQHAvgrdltreerLHTVLAAAKEVGRPTFFGVAIITLVYVPILSLTGIEGKMFEPMALTVIFALIGA 494
Cdd:PRK09579 404 VVVENIHRHIEEGKSP----------FDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIIS 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 495 LILTLTLMPVLCSFGLRGR-----VAEGDGWLVRALKRLYVPVLARALRWRWAVVGGGLALCGLAAALFGRLGAEFVPQL 569
Cdd:PRK09579 474 GIVALTLSPMMCALLLRHEenpsgLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSELAPEE 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 570 DEGSFATFMIRTNSIGLEASLAMQERGERLLREkFPLVTHTFSRIGTAEVATDPMGvnvadtyIFYRPFAEWPRDEHGDG 649
Cdd:PRK09579 554 DQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKS-FPEYYSSFQINGFNGVQSGIGG-------FLLKPWNERERTQMELL 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 650 PtkdEVADAMAEILGTHLPGeahlFSQPiemrfneILEGTRADIAVKVF---GDDFERIEAIASEVREILEQVPGAADVE 726
Cdd:PRK09579 626 P---LVQAKLEEIPGLQIFG----FNLP-------SLPGTGEGLPFQFVintANDYESLLQVAQRVKQRAQESGKFAFLD 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 727 FDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLRSALEELKHLPLRlaHAD 806
Cdd:PRK09579 692 IDLAFDKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVK--NEQ 769
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 807 GVI----TLGDVAEFVVTEKVNAIAresgQRRAAImvnLRGRDVESFVHEAQA-RVRAQVELPAGYAIEFGGQFKNLQEA 881
Cdd:PRK09579 770 GQLlplsTLITLSDRARPRQLNQFQ----QLNSAI---ISGFPIVSMGEAIETvQQIAREEAPEGFAFDYAGASRQYVQE 842
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 882 RGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVAVLNGLMLVSTF 961
Cdd:PRK09579 843 GSALWVTFGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFA 922
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 962 NQLREE-GWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTLVMLPVLYEWS 1040
Cdd:PRK09579 923 NQLRHEqGLSRREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLL 1002
|
1050
....*....|...
gi 501344150 1041 EARLARRRAEGKT 1053
Cdd:PRK09579 1003 AKPDAAPGVAQAA 1015
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
34-1048 |
6.87e-60 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 223.07 E-value: 6.87e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 34 LPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMTELRSLSKTGLSQVTLVFEDGVDVyrvrqlvser 113
Cdd:PRK10614 32 LPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRIILQFDFDRDI---------- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 114 lAGAAKELPAGLTPMLAPITSGLSDIFYYvvdYAENAPDKP----ATRAEQLRELQLiHDFV---IKPQLRTVRGVVEVN 186
Cdd:PRK10614 102 -NGAARDVQAAINAAQSLLPSGMPSRPTY---RKANPSDAPimilTLTSDTYSQGQL-YDFAstqLAQTISQIDGVGDVD 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 187 ASGGYEKQIIVQPRPDALLAAGVTFHELAE-IVGENVENAGGgAVQIGGEQLSIRADSRVRSTEEISRLPLKFRGAgiAP 265
Cdd:PRK10614 177 VGGSSLPAVRVGLNPQALFNQGVSLDDVRQaISNANVRRPQG-AVEDGTHRWQIQTNDELKTAAEYQPLIIHYNNG--AA 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 266 LLVSDVADVV--VGSSLRTGTAthNGREALLGAALMLTGENARLVARRVADKLAEIQPRLPAGVTLTTVYDRTDLVDRTI 343
Cdd:PRK10614 254 VRLGDVATVTdsVQDVRNAGMT--NAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAIDLQIAQDRSPTIRASL 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 344 RTVRKNLFEGAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMSLGA--VDFGLIIDGAVVMVENIV 421
Cdd:PRK10614 332 EEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMAltIATGFVVDDAIVVLENIS 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 422 RRIGARQhavgrdltreERLHTVLAAAKEVGrptfFGVAIITL----VYVPILSLTGIEGKMFEPMALTVIFALIGALIL 497
Cdd:PRK10614 412 RHLEAGM----------KPLQAALQGVREVG----FTVLSMSLslvaVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLV 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 498 TLTLMPVLCSFGLRGRVAEGDGWLvRALKRLYVPV---LARALRW-----RWaVVGGGLALCGLAAALFGRLGAEFVPQL 569
Cdd:PRK10614 478 SLTLTPMMCAWLLKSSKPREQKRL-RGFGRMLVALqqgYGRSLKWvlnhtRW-VGVVLLGTIALNVWLYISIPKTFFPEQ 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 570 DEGSFATFMIRTNSIGLEaslAMQERGERLLRekfplVTHTFSRIGTAEVATDPMGVNVADTYIFYRPFAEwpRDEhgdg 649
Cdd:PRK10614 556 DTGRLMGFIQADQSISFQ---AMRGKLQDFMK-----IIRDDPAVDNVTGFTGGSRVNSGMMFITLKPLSE--RSE---- 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 650 pTKDEVADAMAEILgTHLPGeAHLFSQPIEmrfnEILEGTR---ADIAVKVFGDDFERIEAIASEVREILEQVPGAADVE 726
Cdd:PRK10614 622 -TAQQVIDRLRVKL-AKEPG-ANLFLMAVQ----DIRVGGRqsnASYQYTLLSDDLAALREWEPKIRKALAALPELADVN 694
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 727 FDALGKAPLLEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLR---SALEElkhlpLRLA 803
Cdd:PRK10614 695 SDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTqdiSALEK-----MFVI 769
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 804 HADG-VITLGDVAEFVVTEKVNAIARESGQRRAAIMVNLRGRDVESFVHEAQARVRAQVELPAGYAIEFGGQFKNLQEAR 882
Cdd:PRK10614 770 NNEGkAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIERAMTQLGVPSTVRGSFAGTAQVFQETM 849
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 883 GRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVAVLNGLMLVS-TF 961
Cdd:PRK10614 850 NSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDfAL 929
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 962 NQLREEGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTLVMLPVLYEWSE 1041
Cdd:PRK10614 930 EAQRNGNLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFD 1009
|
....*..
gi 501344150 1042 aRLARRR 1048
Cdd:PRK10614 1010 -RLRLRF 1015
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
34-1048 |
9.33e-48 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 185.70 E-value: 9.33e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 34 LPIDVTPDITPVQVQINTEVKGLAPEEIENLVTFPIEMQMSGVPGMTELRSLSKTGLSQVTLVFEDGVDVYRVRQLVSER 113
Cdd:PRK10503 41 LPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAA 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 114 LAGAAKELPAGLTpmLAPITSGLSDIFYYVVDYAENAPDKPATRAEQLRELQlihdfvIKPQLRTVRGVVEVNASGGYEK 193
Cdd:PRK10503 121 INAATNLLPSDLP--NPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETR------VAQKISQVSGVGLVTLSGGQRP 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 194 QIIVQPRPDALLAAGVTFHEL-AEIVGENVeNAGGGAVQIGGEQLSIRADSRVRSTEEISRLPLKFRGAgiAPLLVSDVA 272
Cdd:PRK10503 193 AVRVKLNAQAIAALGLTSETVrTAITGANV-NSAKGSLDGPTRAVTLSANDQMQSAEEYRQLIIAYQNG--APIRLGDVA 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 273 DVVVGSSLRTGTATHNGREALLGAALMLTGENARLVARRVADKLAEIQPRLPAGVTLTTVYDRTDLVDRTIRTVRKNLFE 352
Cdd:PRK10503 270 TVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELML 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 353 GAILVIAVLLGLLGNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMSLGAVDF--GLIIDGAVVMVENIVRRIgarqha 430
Cdd:PRK10503 350 AIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIatGFVVDDAIVVIENISRYI------ 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 431 vgrdltreERLHTVLAAA-KEVGRptfFGVAIITL------VYVPILSLTGIEGKMFEPMALTVIFALIGALILTLTLMP 503
Cdd:PRK10503 424 --------EKGEKPLAAAlKGAGE---IGFTIISLtfsliaVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTP 492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 504 VLCSFGLRGRVAEGDGWLVRALKRL-------YVPVLARALRWRWAVVGGGLALCGLAAALFGRLGAEFVPQLDEGSFAT 576
Cdd:PRK10503 493 MMCARMLSQESLRKQNRFSRASERMfdrviaaYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGFFPVQDNGIIQG 572
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 577 FMIRTNSIGLeASLAMQERGERLLREKFPLVTHTFSRIGTAevATDPmGVNVADTYIFYRPFAEwpRDEHgdgptKDEVA 656
Cdd:PRK10503 573 TLQAPQSSSF-ANMAQRQRQVADVILQDPAVQSLTSFVGVD--GTNP-SLNSARLQINLKPLDE--RDDR-----VQKVI 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 657 DAMAEILGThLPGeAHLFSQPIE-MRFNEILEGTRADIAVKvfGDDFERIEAIASEVREILEQVPGAADVEFDALGKAPL 735
Cdd:PRK10503 642 ARLQTAVAK-VPG-VDLYLQPTQdLTIDTQVSRTQYQFTLQ--ATSLDALSTWVPKLMEKLQQLPQLSDVSSDWQDKGLV 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 736 LEIRLNREAMTRYNVHAAEVNATVATALAGEEVGTIVDGNRRYPILVRLPERLRSALEELKHlpLRLAHADGVITlgdva 815
Cdd:PRK10503 718 AYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDT--IRLTSSDGGVV----- 790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 816 efvvteKVNAIARESgQRRAAIMVN--------------LRGRDVESFVhEAQARVRAQVELPAGYAIEFGGQFKNLQEA 881
Cdd:PRK10503 791 ------PLSSIATIE-QRFGPLSINhldqfpsttisfnvPDGYSLGDAV-QAIMDTEKTLNLPADITTQFQGSTLAFQSA 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 882 RGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVAVLNGLMLVS-T 960
Cdd:PRK10503 863 LGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDfA 942
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 961 FNQLREEGWNVAEAVREGALTRLRPVLMTALVASLGFLPMALSNGAGAEVQRPLATVVIGGIVTSTFLTLVMLPVLYEWS 1040
Cdd:PRK10503 943 LAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPVIYLLF 1022
|
....*...
gi 501344150 1041 EaRLARRR 1048
Cdd:PRK10503 1023 D-RLALYT 1029
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
835-1052 |
1.23e-15 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 81.83 E-value: 1.23e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 835 AAIMVNLRGRDVESF--VHEAQARVRAQVEL--PAGYAIEFGGQFK----NLQEARGRLAIIVPLALAVIFLLIFAAFGS 906
Cdd:COG1033 162 TLIVVTLDPDPLSSDldRKEVVAEIRAIIAKyeDPGVEVYLTGFPVlrgdIAEAIQSDLAIFFPLALLLILLLLFLFFRS 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 907 LRqalvvYTGIPLAITGGVVA-----LALRGLPFSISAGIGFIALSGVAVLNGLMLVSTFNQLREEGWNVAEAVREgALT 981
Cdd:COG1033 242 LR-----GVLLPLLVVLLAVIwtlglMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALRE-ALR 315
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 501344150 982 RL-RPVLMTALVASLGFLPMALSN-GAGAEvqrpLATVVIGGIVTSTFLTLVMLPVLYEWSEARLARRRAEGK 1052
Cdd:COG1033 316 KLgPPVLLTSLTTAIGFLSLLFSDiPPIRD----FGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKK 384
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
830-1048 |
7.52e-14 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 76.05 E-value: 7.52e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 830 SGQRRAAIMV---NLRGRDVESFVHEAQARVRAQVElPAGYAIEFGGQ---FKNLQEA--RGRLAIIVpLALAVIFLLIF 901
Cdd:COG1033 546 EDYSAARVTVrlkDLDSEEIKALVEEVRAFLAENFP-PDGVEVTLTGSavlFAAINESviESQIRSLL-LALLLIFLLLL 623
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 902 AAFGSLRQAL--VVYTGIPLAITGGVvaLALRGLPFSIS-AGIGFIALsGVAVLNGLMLVSTFNQLREEGWNVAEAVREG 978
Cdd:COG1033 624 LAFRSLRLGLisLIPNLLPILLTFGL--MGLLGIPLNIAtAVVASIAL-GIGVDYTIHFLSRYREERRKGGDLEEAIRRA 700
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 979 ALTRLRPVLMTALVASLGFLPMALSNGAGaevQRPLATVVIGGIVTSTFLTLVMLPVLYEWSEARLARRR 1048
Cdd:COG1033 701 LRTTGKAILFTSLTLAAGFGVLLFSSFPP---LADFGLLLALGLLVALLAALLLLPALLLLLDPRIAKKR 767
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
300-508 |
2.18e-08 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 58.33 E-value: 2.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 300 LTGENARLVARRVADKLAEIQPRLPAGVTLTtvyDRTDLVDRTIRTVRKNLFEG---AILVIAVLLGLL-GNWRAALI-- 373
Cdd:COG1033 560 LDSEEIKALVEEVRAFLAENFPPDGVEVTLT---GSAVLFAAINESVIESQIRSlllALLLIFLLLLLAfRSLRLGLIsl 636
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 374 VSLAIPLSFLFAItgMVRFGVSGNLMSL--GAVDFGLIIDGAVVMVENIvrrigarQHAVGRDLTREERLHTVLaaaKEV 451
Cdd:COG1033 637 IPNLLPILLTFGL--MGLLGIPLNIATAvvASIALGIGVDYTIHFLSRY-------REERRKGGDLEEAIRRAL---RTT 704
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 501344150 452 GRPTFFGvAIITLVYVPILSLTGIegKMFEPMALTVIFALIGALILTLTLMPVLCSF 508
Cdd:COG1033 705 GKAILFT-SLTLAAGFGVLLFSSF--PPLADFGLLLALGLLVALLAALLLLPALLLL 758
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
835-1051 |
6.12e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 53.69 E-value: 6.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 835 AAIMVNLRGRDVESFVHEAQARVRAQVE---LPAGYAIEFGG----QFKNLQEARGRLAIIVPLALAVIFLLIFAAFGSL 907
Cdd:TIGR00921 138 AIIIVQLKSDADYKQVVPIYNDVERSLErtnPPSGKFLDVTGspaiNYDIEREFGKDMGTTMAISGILVVLVLLLDFKRW 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 908 RQALVVYTGIPLAITGGVVALALRGLPFSISAGIGFIALSGVAVLNGLMLVSTFNQLREEGWNVAEAVREGALTRLRPVL 987
Cdd:TIGR00921 218 WRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVL 297
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 501344150 988 MTALVASLGFLPMALSngaGAEVQRPLATVVIGGIVTSTFLTLVMLPVLY----EWSEARLARRRAEG 1051
Cdd:TIGR00921 298 IALLTTSAGFAALALS---EFPMVSEFGLGLVAGLITAYLLTLLVLPALLqsidIGREKVKKEIIAIG 362
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
835-1036 |
9.27e-06 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 49.76 E-value: 9.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 835 AAIMVNLRGrDVESFVHEAQARVRAQVE--LPAGYAIEFGGQ-------FKNLQEARGRLAIIvplALAVIFLLIFAAFG 905
Cdd:COG2409 116 ALVTVTLDG-DAGDEAAEAVDALRDAVAaaPAPGLTVYVTGPaalaadlNEAFEEDLGRAELI---TLPVALVVLLLVFR 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 906 SLRQALV--VYTGIPLAITGGVVALALRGLPFSISA-GIGFIALSGVAVLNGLMLVSTFNQLREEGWNVAEAVREGALTR 982
Cdd:COG2409 192 SLVAALLplLTAGLAVGVALGLLALLAAFTDVSSFApNLLTMLGLGVGIDYALFLVSRYREELRAGEDREEAVARAVATA 271
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 501344150 983 LRPVLMTALVASLGFLPMALsngAGAEVQRPLATVVIGGIVTSTFLTLVMLPVL 1036
Cdd:COG2409 272 GRAVLFSGLTVAIALLGLLL---AGLPFLRSMGPAAAIGVAVAVLAALTLLPAL 322
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
852-1036 |
1.41e-05 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 48.44 E-value: 1.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 852 EAQARVRAQVELPAGYAIEFGG---QFKNLQEARGR-LAIIVPLALAVIFLLIFAAFGSLRQALVVYT--GIPLAITGGV 925
Cdd:pfam03176 107 AAVRDAVEQAPPPEGLKAYLTGpaaTVADLRDAGDRdLGLIEAVTLVVIFIILLIVYRSVVAALLPLLtvGLSLGAAQGL 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 926 VALALRGLPFSIS---AGIGFIALSGVAVLNGLMLVSTFNQLREEGWNVAEAVREGALTRLRPVLMTALVASLGFLPMAL 1002
Cdd:pfam03176 187 VAILAHILGIGLStfaLNLLVVLLIAVGTDYALFLVSRYREELRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSF 266
|
170 180 190
....*....|....*....|....*....|....
gi 501344150 1003 SNgagAEVQRPLATVVIGGIVTSTFLTLVMLPVL 1036
Cdd:pfam03176 267 AR---LPVFAQVGPTIAIGVLVDVLAALTLLPAL 297
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
879-1037 |
2.95e-05 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 48.31 E-value: 2.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 879 QEARGRLAIIVPLALAVIFLLIFAAFGSLRqaLVVYTGIPLAItGGVVALALRGLPF-SISA---GIGFiALSGVAVLNG 954
Cdd:COG4258 245 QQIKHDISTIGLISLLGILLLLLLVFRSLR--PLLLGLLPVAV-GALAGLAAVSLVFgSVHGitlGFGS-SLIGVAVDYS 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 955 LMLVStfNQLREEGWNVAEAVREgaltRLRPVLMTALVASLGFLPMALSngaGAEVQRPLATVVIGGIVTSTFLTLVMLP 1034
Cdd:COG4258 321 LHYLT--HRRAAGEWDPRAALRR----IWPTLLLGLLTTVLGYLALLFS---PFPGLRQLGVFAAAGLLAAALTTLLWLP 391
|
...
gi 501344150 1035 VLY 1037
Cdd:COG4258 392 LLL 394
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
882-1034 |
1.13e-04 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 46.38 E-value: 1.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 882 RGRLAIIVPLALAVIFLLIFAAFGSLRQALVVYtgIPLAITGGVV--ALALRGLPFSISAGIGFIALSGVAVLNGLMLVS 959
Cdd:COG4258 638 RNDALWLLLLALLLILLLLLLRLRSLRRALRVL--LPPLLAVLLTlaILGLLGIPLNLFHLIALLLVLGIGIDYALFFTE 715
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 501344150 960 tfnqlreegwnvAEAVREGALTRLRPVLMTALVASLGFLPMALSngagaEVQ--RPLATVVIGGIVTSTFLTLVMLP 1034
Cdd:COG4258 716 ------------GLLDKGELARTLLSILLAALTTLLGFGLLAFS-----STPalRSFGLTVLLGILLALLLAPLLAP 775
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
4-505 |
2.34e-04 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 45.36 E-value: 2.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 4 RILEFALRQRVFVLLGALLLVVVGSWAALRLPIDVTPDI--------------------TPVQVQINTEVKglAPEEIEN 63
Cdd:pfam00873 518 KLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEdegvfvtsaqlppgvsldqtQRVMKQVEKILK--EKPEVES 595
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 64 LVTFPiemqmsGVPGMTELRSLSKtGLSQVTLV-FEDGVDVYRVRQLVSERLAGAAKELPAGLTPMLAPI------TSGL 136
Cdd:pfam00873 596 VFAVT------GFAFSGDNNGPNS-GDAFISLKpWKERPGPEKSVQALIERLRKALKQIPGANVFLFQPIqlrglgTISG 668
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 137 SDIFYYVVDYAENAPDKPATRaEQLRELqlihdfvikpqLRTVRGVVEVNaSGGYEKQIIVQPRPDALLAA--GVTFHEl 214
Cdd:pfam00873 669 FRSDLQVKIFGDDLDALDEAR-NQILAA-----------LAQLPGLSDVR-SDGQEDQPQLQVNIDREKAArlGVSIQD- 734
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 215 aeiVGENVENAGGGAV----QIGGEQ--LSIRADSRVR-STEEISRLPLKFRGAGIAPLlvSDVADVVVGSSlrtgtATH 287
Cdd:pfam00873 735 ---INDTLSTALGGSYvndfPEGGRVydVVVQLPEDFRsSPEDIGQLYVRNPYGKMIPL--SAFAKIEWGYG-----PPS 804
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 288 NGREALLGAALMLTGENARLVARRVADKLAEI--QPRLPAGVTLTtvYDRTDLVDRTIRTVRKNLFEGAILVIAVLLGLL 365
Cdd:pfam00873 805 INRYNGFRSIVISGNVAAGDSLGDAMEAMAQIakQVKLPPGYGYT--WTGQFEQEQLAGNSLPILIALALLVVFLVLAAL 882
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 366 -GNWRAALIVSLAIPLSFLFAITGMVRFGVSGNLMSL-GAVD-FGLIIDGAVVMVENivrrigARQHAVGRDLTREErlh 442
Cdd:pfam00873 883 yESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQvGLILlIGLAVKNAILMVEF------ANELREQEGKSLEE--- 953
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 501344150 443 TVLAAAKEVGRPTFFGVAIITLVYVPILSLTGIEGKMFEPMALTVIFALIGALILTLTLMPVL 505
Cdd:pfam00873 954 AILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVF 1016
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
865-1037 |
5.09e-04 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 44.06 E-value: 5.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 865 AGYAIEFGGQFKNLQEARGRLAIIvplALAVIFLLIFAAFGSLRQALVVYTGIPLAITGGVVALALRGLPFS-ISAGIGF 943
Cdd:TIGR00921 552 TGLPVAFAEMHELVNEGMRRMTIA---GAILVLMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGIPSFlAMATTIS 628
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501344150 944 IALsGVAVLNGLMLVSTFNQLREEGWNVaEAVREgALTRLRP-VLMTALVASLGFLPMALSNgagAEVQRPLATVVIGGI 1022
Cdd:TIGR00921 629 IIL-GLGMDYSIHLAERYFEERKEHGPK-EAITH-TMERTGPgILFSGLTTAGGFLSLLLSH---FPIMRNFGLVQGIGV 702
|
170
....*....|....*
gi 501344150 1023 VTSTFLTLVMLPVLY 1037
Cdd:TIGR00921 703 LSSLTAALVVFPALL 717
|
|
| |
