NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|502771768|ref|WP_013006752|]
View 

DnaA N-terminal domain-containing protein [Rickettsia amblyommatis]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DnaA_N pfam11638
DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a ...
 717-778 3.09e-10

DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a protein involved in the initiation of bacterial chromosomal replication. The structure of this domain is known. It is also found in three copies in some proteins. The exact function of this domain is uncertain but it has been suggested to play a role in oligomerization.


:

Pssm-ID: 463316 [Multi-domain]  Cd Length: 65  Bit Score: 56.52  E-value: 3.09e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 502771768  717 NTAWHHIRQGLIEELGEAMYTAWFEKAVVKECNDTSTLKFTMPARFIADWVRNNYSHVIQRL 778
Cdd:pfam11638   1 EELWERVLERLRKEVGEQTFNTWIKPLTLVDLDDGGSLTLSVPNRFVRDWVEEHYLDRILEL 62
HTH_Crp_2 pfam13545
Crp-like helix-turn-helix domain; This family represents a crp-like helix-turn-helix domain ...
 278-315 1.88e-03

Crp-like helix-turn-helix domain; This family represents a crp-like helix-turn-helix domain that is likely to bind DNA.


:

Pssm-ID: 463917 [Multi-domain]  Cd Length: 68  Bit Score: 37.44  E-value: 1.88e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 502771768  278 SYQELQKELKLHRNSISRALKDLEDNNLIKRDKLVIRN 315
Cdd:pfam13545  24 TQEDLADLLGTTRETVSRVLSELRREGLIERGRITILD 61
 
Name Accession Description Interval E-value
DnaA_N pfam11638
DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a ...
 717-778 3.09e-10

DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a protein involved in the initiation of bacterial chromosomal replication. The structure of this domain is known. It is also found in three copies in some proteins. The exact function of this domain is uncertain but it has been suggested to play a role in oligomerization.


Pssm-ID: 463316 [Multi-domain]  Cd Length: 65  Bit Score: 56.52  E-value: 3.09e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 502771768  717 NTAWHHIRQGLIEELGEAMYTAWFEKAVVKECNDTSTLKFTMPARFIADWVRNNYSHVIQRL 778
Cdd:pfam11638   1 EELWERVLERLRKEVGEQTFNTWIKPLTLVDLDDGGSLTLSVPNRFVRDWVEEHYLDRILEL 62
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 720-788 7.62e-07

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 52.15  E-value: 7.62e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 502771768  720 WHHIRQGLIEELGEAMYTAWFEKAVVKECNDtSTLKFTMPARFIADWVRNNYSHVIQRLGSSAGVKRVE 788
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLLSIEG-NTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIE 68
dnaA PRK00149
chromosomal replication initiator protein DnaA;
715-778 4.99e-06

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 49.75  E-value: 4.99e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502771768 715 EANTAWHHIRQGLIEELGEAMYTAWFEKAVVKECNDtSTLKFTMPARFIADWVRNNYSHVIQRL 778
Cdd:PRK00149   1 NLQSLWEKVLERLKDELSEQEYETWIKPLKALSLED-NTLTLYVPNRFVKDWIEKNYLDLIEEA 63
HTH_Crp_2 pfam13545
Crp-like helix-turn-helix domain; This family represents a crp-like helix-turn-helix domain ...
 278-315 1.88e-03

Crp-like helix-turn-helix domain; This family represents a crp-like helix-turn-helix domain that is likely to bind DNA.


Pssm-ID: 463917 [Multi-domain]  Cd Length: 68  Bit Score: 37.44  E-value: 1.88e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 502771768  278 SYQELQKELKLHRNSISRALKDLEDNNLIKRDKLVIRN 315
Cdd:pfam13545  24 TQEDLADLLGTTRETVSRVLSELRREGLIERGRITILD 61
COG2512 COG2512
Predicted transcriptional regulator, contains CW (cell wall-binding) repeats and an HTH domain ...
 280-311 1.91e-03

Predicted transcriptional regulator, contains CW (cell wall-binding) repeats and an HTH domain [General function prediction only];


Pssm-ID: 442002 [Multi-domain]  Cd Length: 80  Bit Score: 37.59  E-value: 1.91e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 502771768 280 QELQKELKLHRNSISRALKDLEDNNLIKRDKL 311
Cdd:COG2512   34 SEIVKETGWSKSKVSRLLSRLEERGLIEKERV 65
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
278-332 7.40e-03

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 36.80  E-value: 7.40e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 502771768   278 SYQELQKELKLHRNSISRALKDLEDNNLIKRDKlvirnnddynSRADKSLWQISL 332
Cdd:smart00347  26 SVSELAKRLGVSPSTVTRVLDRLEKKGLVRREP----------SPEDRRSVLVSL 70
 
Name Accession Description Interval E-value
DnaA_N pfam11638
DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a ...
 717-778 3.09e-10

DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a protein involved in the initiation of bacterial chromosomal replication. The structure of this domain is known. It is also found in three copies in some proteins. The exact function of this domain is uncertain but it has been suggested to play a role in oligomerization.


Pssm-ID: 463316 [Multi-domain]  Cd Length: 65  Bit Score: 56.52  E-value: 3.09e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 502771768  717 NTAWHHIRQGLIEELGEAMYTAWFEKAVVKECNDTSTLKFTMPARFIADWVRNNYSHVIQRL 778
Cdd:pfam11638   1 EELWERVLERLRKEVGEQTFNTWIKPLTLVDLDDGGSLTLSVPNRFVRDWVEEHYLDRILEL 62
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 720-788 7.62e-07

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 52.15  E-value: 7.62e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 502771768  720 WHHIRQGLIEELGEAMYTAWFEKAVVKECNDtSTLKFTMPARFIADWVRNNYSHVIQRLGSSAGVKRVE 788
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLLSIEG-NTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIE 68
dnaA PRK00149
chromosomal replication initiator protein DnaA;
715-778 4.99e-06

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 49.75  E-value: 4.99e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502771768 715 EANTAWHHIRQGLIEELGEAMYTAWFEKAVVKECNDtSTLKFTMPARFIADWVRNNYSHVIQRL 778
Cdd:PRK00149   1 NLQSLWEKVLERLKDELSEQEYETWIKPLKALSLED-NTLTLYVPNRFVKDWIEKNYLDLIEEA 63
HTH_Crp_2 pfam13545
Crp-like helix-turn-helix domain; This family represents a crp-like helix-turn-helix domain ...
 278-315 1.88e-03

Crp-like helix-turn-helix domain; This family represents a crp-like helix-turn-helix domain that is likely to bind DNA.


Pssm-ID: 463917 [Multi-domain]  Cd Length: 68  Bit Score: 37.44  E-value: 1.88e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 502771768  278 SYQELQKELKLHRNSISRALKDLEDNNLIKRDKLVIRN 315
Cdd:pfam13545  24 TQEDLADLLGTTRETVSRVLSELRREGLIERGRITILD 61
COG2512 COG2512
Predicted transcriptional regulator, contains CW (cell wall-binding) repeats and an HTH domain ...
 280-311 1.91e-03

Predicted transcriptional regulator, contains CW (cell wall-binding) repeats and an HTH domain [General function prediction only];


Pssm-ID: 442002 [Multi-domain]  Cd Length: 80  Bit Score: 37.59  E-value: 1.91e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 502771768 280 QELQKELKLHRNSISRALKDLEDNNLIKRDKL 311
Cdd:COG2512   34 SEIVKETGWSKSKVSRLLSRLEERGLIEKERV 65
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
278-332 7.40e-03

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 36.80  E-value: 7.40e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 502771768   278 SYQELQKELKLHRNSISRALKDLEDNNLIKRDKlvirnnddynSRADKSLWQISL 332
Cdd:smart00347  26 SVSELAKRLGVSPSTVTRVLDRLEKKGLVRREP----------SPEDRRSVLVSL 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH