|
Name |
Accession |
Description |
Interval |
E-value |
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
5-883 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1213.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 5 TAQELREAWKQFYKDRGHVDCGAVSLVSDGSTGVMFNVAGMQPLMPYLLGKKHPMGTRLCNVQGCVRT----NDIDSVG- 79
Cdd:COG0013 3 TSAEIRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKPPYPRATTSQKCVRTggkhNDLENVGy 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 80 DKSHGTFFEMMGSWSLGDYFKKERCQWSFELLTQLFGFDADHLAATVFAGDENAprdeegakYRI---ESGFKPENIYYL 156
Cdd:COG0013 83 TARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDDDEA--------YDIwkkEIGVPEERIIRL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 157 PAEDNWWGL-EYGPCGPDSEMFYvkDM---PDCGPNCGPGCHCGKYTEIGNDVFMQYEKHHDGHLTPLTQKNVDTGWGLE 232
Cdd:COG0013 155 GKKDNFWEMgDTGPCGPCSEIFY--DRgpeYGGGPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTGMGLE 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 233 RILAFLNGVDDVYKIDLHAPVIAYIEKESGLKYESDEKTTRSMRILADHTRTSVMLIGDEAklLPSNTGAGYILRRLIRR 312
Cdd:COG0013 233 RIAAVLQGVHSNYETDLFRPLIEAAAELTGVKYGADEEDDVSLRVIADHIRAVAFLIADGV--LPSNEGRGYVLRRILRR 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 313 AVRHARTLGLNKDQILGVATIYIDEYSESYENLAKNRKFVLTELEREITRFESTLENGMKEFRKILDKTSAAGKKEIEGK 392
Cdd:COG0013 311 AVRHGRLLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKLKAAGGKVLSGE 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 393 DAFFLYDTFGFPVELTVELADEEGFTVDEEGFKASMEEQKQKARENQNFSANLSTGTGLFDNLDESVATEFLGYEKLECD 472
Cdd:COG0013 391 DAFKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAAAKFSGDAAVDGVWRELLEEGGPTEFVGYDTLEAE 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 473 GTVAVIAGADALVTELTEGQQGTIITDKTTFYGTMGGQVGDIGEILGsNGAKFEVTEAVKVAGGRTAHVGKVVSGSFKVS 552
Cdd:COG0013 471 AKVLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEG-DGGVFEVTDTQKPPGGLIVHIGKVEEGELKVG 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 553 DKVTLSVDAENRAKTCRNHSATHLLQKALQMVLGDGVEQAGSYQDPDKTRFDFSYHQAMTADEIKKVEDIVNSKILEALP 632
Cdd:COG0013 550 DTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLP 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 633 VVTKEMSIEDAKKTGAMALFGEKYGETVRVVNMGDFSIELCGGTHVANTSHIGLFKILSESGVAAGVRRIEALTGDNARA 712
Cdd:COG0013 630 VETREMPLDEAKALGAMALFGEKYGDEVRVVSIGDFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALE 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 713 YYKNVEANLGEAAKTLKTTPADLVDHIKKLQEELKNLRSENESLKSKEAQAALGDVMDQVLEIKGVKLLATSVKGVDMNG 792
Cdd:COG0013 710 YLREQEALLKELAELLKAPPEELPERVEALLEELKELEKELEQLKAKLASAAADDLLAQAEEIGGVKVLAARVEGVDAKD 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 793 LRDLGDQMKTKLGEGVVVLISEADGKVNLVTMATDGAMAKGAHAGNLVKAIAPKVGGGGGGRPNMAQAGGKNPAGIQDAL 872
Cdd:COG0013 790 LRDLADDLKDKLGSGVVVLASVADGKVSLVAGVTKDLVKKGLKAGDLVKEVAKIVGGGGGGRPDMAQAGGKDPSKLDEAL 869
|
890
....*....|.
gi 503045638 873 AEAKTVLLSQI 883
Cdd:COG0013 870 AAVKEWLAEKL 880
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
8-862 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 814.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 8 ELREAWKQFYKDRGHVDCGAVSLVSDGSTGVMFNVAGMQPLMPYLLGKKHPMGTRLCNVQGCVRTNDIDSVGDKS-HGTF 86
Cdd:TIGR00344 1 EIRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPSNRLTNAQPCIRLNDLENVGRTArHHTL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 87 FEMMGSWSLGDYFKKERCQWSFELLTQLFGFDADHLAATVFagdenaPRDEEGAKYRIESGFKPENIYYLPAEDNWWGLE 166
Cdd:TIGR00344 81 FEMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVY------EDDEEAYKIWEKIGIPADRIIKCDAKDNFWDMG 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 167 YGPCGPDSEMFYVKDMpdcGPNCGPGCHCGKYTEIGNDVFMQYEKHHDGHLTPLTQKNVDTGWGLERILAFLNGVDDVYK 246
Cdd:TIGR00344 155 DGPCGPCTEIYYDFVG---GKPGEPLEENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVAVLQGVPTNYD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 247 IDLHAPVIAYIEKESGLKYESDE---------KTTRSMRILADHTRTSVMLIGDeaKLLPSNTGAGYILRRLIRRAVRHA 317
Cdd:TIGR00344 232 TDIFLPLIEKIEEITGVKYDSNNagimdekrvEDLRSLRVIADHTRAIAFMLAD--GVVPSNEGRGYVLRRLIRRALRHG 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 318 RTLGLNKDQILGVATIYIDEYSESYENLAKNRKFVLTELEREITRFESTLENGMKEFRKILDKTsaaGKKEIEGKDAFFL 397
Cdd:TIGR00344 310 KKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKT---GKKELDGEDAFKL 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 398 YDTFGFPVELTVELADEEGFTVDEEGFKASMEEQKQKARENQNFSANlstgtglFDNL-DESVATEFLGYEKLECDGTVA 476
Cdd:TIGR00344 387 YDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQFQEQ-------EIALvNVYPATEFLGYDDLEFEAKVI 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 477 VIAGADALVTELTEGQQGTIITDKTTFYGTMGGQVGDIGEILGsNGAKFEVtEAVKVAGGRTAHVGKVVSGSFKVSDKVT 556
Cdd:TIGR00344 460 GLFDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIA-NDGKFRV-VDVQKPNGVVFHFGEVEGGSLKVGDKVI 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 557 LSVDAENRAKTCRNHSATHLLQKALQMVLGDGVEQAGSYQDPDKTRFDFSYHQAMTADEIKKVEDIVNSKILEALPVVTK 636
Cdd:TIGR00344 538 AVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREELEEIEDLANEQILANIPIKVI 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 637 EMSIEDAKKTGAMALFGEKY--GETVRVVNMGDFSIELCGGTHVANTSHIGLFKILSESGVAAGVRRIEALTGDNARAYY 714
Cdd:TIGR00344 618 FMDLDEAKRKGAFALFGEKYvpGEKVRVVSVGDFSVELCGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYL 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 715 KNVEANLGEAAKTLKTTPADLVDHIKKLQEELKNLRSENESLKSKEAQAALGDVMDQVLEIKGVKLLATSVKGVDMNGLR 794
Cdd:TIGR00344 698 NEQEDKLKELADILKVTPNELPKKVERFFEEWKALQKELESLKLKIADQKIDELKDKAETINGVKVLVEVVDAKDMKSLK 777
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 503045638 795 DLGDQMKTKLGEGVVVLISEADGKVNLVTMATDGAMAKGAHAGNLVKAIAPKVGGGGGGRPNMAQAGG 862
Cdd:TIGR00344 778 TMADRLKSKLGSAIYVLASFAEGKVKLVCGVSNDVLTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
1-881 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 751.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 1 MKQFTAQELREAWKQFYKDRGHVDCGAVSLVSDGSTGVMFNVAGMQPLMPYLLGKKHPMG-----TRLCNVQGCVRT--- 72
Cdd:PLN02900 8 EKEWPGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTplrklPRATNTQKCIRAggk 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 73 -NDIDSVG-DKSHGTFFEMMGSWSLGDYFKKERCQWSFELLTQLFGFDADHLAATVFAGDENAPRDEEGakYRIESGFKP 150
Cdd:PLN02900 88 hNDLDDVGkDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEKQAPDDEA--RAIWLDYLP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 151 EN-IYYLPAEDNWWGL-EYGPCGPDSEMFY----------VKDMPDcgPNCgpgchcgkyTEIGNDVFMQYEKHHDGHLT 218
Cdd:PLN02900 166 EErVLPFGCKDNFWEMgDTGPCGPCSEIHYdrigerdaadLVNNDD--PRF---------IEIWNLVFIQFNREADGSLK 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 219 PLTQKNVDTGWGLERILAFLNGVDDVYKIDLHAPVIAYIEKESGLKY-------ESDEKTTRSMRILADHTRTSVMLIGD 291
Cdd:PLN02900 235 PLPAKHVDTGMGLERLASILQNKPSNYDTDLFMPIFDAIQEATGARPyagkvgaEDDDRVDMAYRVVADHIRTLSFAIAD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 292 EAklLPSNTGAGYILRRLIRRAVRHARTLGLNKDQIL-GVATIYIDEYSESYENLAKNRKFVLTELEREITRFESTLENG 370
Cdd:PLN02900 315 GV--VPSNEGRGYVLRRLLRRAVRYGRLLLGAEEGFFpALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKG 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 371 MKEFRKILDKTSAAGKKEIEGKDAFFLYDTFGFPVELTVELADEEGFTVDEEGFKASMEEQKQKARENQNFSANLS---- 446
Cdd:PLN02900 393 IEKFKKALAAAKANGGPVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRAAHLKAGGGAiela 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 447 -TGTGLFDNLDESVATEFLGYEKLEC-DGTVAVIAGADALVTELTEGQQGTIITDKTTFYGTMGGQVGDIGEILGSNGAK 524
Cdd:PLN02900 473 aEATSWLQKQGVAATDDFLKYDWLSDhEAVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEGSGGAV 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 525 FEVTEaVKVAGGRTAHVGKVVSGSFKVSDKVTLSVDAENRAKTCRNHSATHLLQKALQMVLGDGVEQAGSYQDPDKTRFD 604
Cdd:PLN02900 553 VEVSD-VQKAGGFVLHIGTVTEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFD 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 605 FSYHQAMTADEIKKVEDIVNSKILEALPVVTKEMSIEDAKKT-GAMALFGEKYGETVRVVNMGD-FSIELCGGTHVANTS 682
Cdd:PLN02900 632 FSHGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRInGLRAVFGEKYPDPVRVVSVGGvYSMELCGGTHVSNTA 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 683 HIGLFKILSESGVAAGVRRIEALTGDNARAYYKNVEANLGEAAKTLKTT------------------------PADLVDH 738
Cdd:PLN02900 712 EAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDSALKVEgsdlekkvaslksrvdaavipaakKEEIRAR 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 739 IKKLQEELKNLRSENESLKSKEAQAALGDVMDQVLEIKGVKLLATSVKGVDMNGLRDLGDQMKTKLGEGVVVLIS--EAD 816
Cdd:PLN02900 792 VSALQKELRAAQKEAAALRAKLAVAKATELASKALSAGKSVLVARLDVGVDAAALKEAAEKVIAKLGDPAAVVLSsdEEK 871
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 503045638 817 GKVNLVTMATDGAMAKGAHAGNLVKAIAPKVGGGGGGRPNMAQAGGKNPAGIQDALAEAKTVLLS 881
Cdd:PLN02900 872 GKVSLVAAVPPGVVKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALEKARAFAVA 936
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
8-562 |
2.33e-162 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 484.86 E-value: 2.33e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 8 ELREAWKQFYKDRGHVDCGAVSLVSDGSTGVMFNVAGMQPLMPYLLGKKH-PMGTRLCNVQGCVRTNDIDSVG-DKSHGT 85
Cdd:pfam01411 1 EIRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVAkPPYNRATNSQKCIRAGDLENVGrTGRHHT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 86 FFEMMGSWSLGDYFKKERCQWSFELLTQLFGFDADHLAATVFAGDENAprdeeGAKYRIESGFKPENIYYLPAEDNWWGL 165
Cdd:pfam01411 81 FFEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDDEA-----GPIWEKIVGGPEERILRFGDKDNFWEM 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 166 -EYGPCGPDSEMFYvkdmpDCGPNCGPGCHCGK-------YTEIGNDVFMQYEKHHDGHLTPLTQKNVDTGWGLERILAF 237
Cdd:pfam01411 156 gDTGPCGPCSEIDY-----DRGEEIGGWDSGGTptadddrFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGLERLVAV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 238 LNGVDDVYKIDLHAPVIAYIEKESGLKYESDEKTTRSMRILADHTRTSVMLIGDeaKLLPSNTGAGYILRRLIRRAVRHA 317
Cdd:pfam01411 231 LQDVRSNYDTDVFIPVIELIEEISGARYYTVDETDEAYRVIADHTRALTFALAD--GVVPSNEGRGYVLRRILRRAVRHA 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 318 RTLGLNKDQILGVATIYIDEYSESYENLAKNRKFVLTELEREITRFESTLENGMKEFRKILdKTSAAGKKEIEGKDAFFL 397
Cdd:pfam01411 309 KKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLI-AKLKKGKKTLPGEDAFKL 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 398 YDTFGFPVELTVELADEEGFTVDEEGFKASMEEQKQKARENQNFSANLSTGTGLfdnLDESVATEFLGYEKLECDGTVAV 477
Cdd:pfam01411 388 YDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKGEKLDVSAL---KELPATTEFLGYDDLESEAKILA 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 478 IAGADALVTELTEGQQGTIITDKTTFYGTMGGQVGDIGEILGsNGAKFEVTEaVKVAGGRTAHVGKVVSGSFKVSDKVTL 557
Cdd:pfam01411 465 LPKDGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIG-DGGEFRVTD-VQKYGGVVVHKGKLESGKLKVGDKVIA 542
|
....*
gi 503045638 558 SVDAE 562
Cdd:pfam01411 543 VIDED 547
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
6-241 |
1.83e-75 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 246.12 E-value: 1.83e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 6 AQELREAWKQFYKDRGHVDCGAVSLVSDGSTGVMFNVAGMQPLMPYLLGKKHPMGTRLCNVQGCVRTNDIDSVG-DKSHG 84
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPANRLVNSQKCIRAGDIDNVGkTGRHH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 85 TFFEMMGSWSLGDYFKKERCQWSFELLTQLFGFDADHLAATVFAGDenaprDEEGAKYRIESGFKPENIYYLPAEDNWWG 164
Cdd:cd00673 81 TFFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGD-----DEEEAIWWWKIGLPGIRIERIGFKDNFWE 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 503045638 165 L-EYGPCGPDSEMFYVKdMPDCGPNCGPGCHCGKYTEIGNDVFMQYEKHHDGHLTPLTQKNVDTGWGLERILAFLNGV 241
Cdd:cd00673 156 MgGNGPCGPCSEIFYDR-GEERDAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERLVWVLQGV 232
|
|
| a_tRNA_ed_AlaXM |
NF040865 |
alanyl-tRNA editing protein AlaXM; |
481-703 |
8.01e-30 |
|
alanyl-tRNA editing protein AlaXM;
Pssm-ID: 468802 [Multi-domain] Cd Length: 234 Bit Score: 118.48 E-value: 8.01e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 481 ADALVTELTEGQqgtIITDKTTFYGTMGGQVGDIGeILGSNGAKFEVTEAVKvAGGRTAHVGKVVSGsFKVSDKVTLSVD 560
Cdd:NF040865 14 FDATVVRVKGNG---VVLDRTAFYPTGGGQPHDTG-TLVRDDKEFRVVDVRK-EGGEIAHVVDRAPG-LKPGDKVKGEID 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 561 AENRAKTCRNHSATHLLQKALQMVLGDGVeqAGSYQDPDKTRFDFSYhQAMTADEIKKVEDIVNSKILEALPVVTKEMSI 640
Cdd:NF040865 88 WDRRYRLMRYHTASHILSAVLYREYGALI--TGGQISPDKARVDFSL-ENFDRELLEEIIEEANEIIAEGIEVKIYWLPR 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 503045638 641 EDAKKTGAMALFGEKYG---ETVRVVNMGDFSIELCGGTHVANTSHIGLFKILSESGVAAGVRRIE 703
Cdd:NF040865 165 EEALKIPGLVRLAKRLPpeiEEVRIVEIEGVDIQADGGTHVKNTGEIGEIKILKRENKGKGNKRLY 230
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
660-702 |
6.37e-22 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 88.98 E-value: 6.37e-22
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 503045638 660 VRVVNMGDFSIELCGGTHVANTSHIGLFKILSESGVAAGVRRI 702
Cdd:smart00863 1 VRVVSIGDFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
5-883 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1213.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 5 TAQELREAWKQFYKDRGHVDCGAVSLVSDGSTGVMFNVAGMQPLMPYLLGKKHPMGTRLCNVQGCVRT----NDIDSVG- 79
Cdd:COG0013 3 TSAEIRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKPPYPRATTSQKCVRTggkhNDLENVGy 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 80 DKSHGTFFEMMGSWSLGDYFKKERCQWSFELLTQLFGFDADHLAATVFAGDENAprdeegakYRI---ESGFKPENIYYL 156
Cdd:COG0013 83 TARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDDDEA--------YDIwkkEIGVPEERIIRL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 157 PAEDNWWGL-EYGPCGPDSEMFYvkDM---PDCGPNCGPGCHCGKYTEIGNDVFMQYEKHHDGHLTPLTQKNVDTGWGLE 232
Cdd:COG0013 155 GKKDNFWEMgDTGPCGPCSEIFY--DRgpeYGGGPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTGMGLE 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 233 RILAFLNGVDDVYKIDLHAPVIAYIEKESGLKYESDEKTTRSMRILADHTRTSVMLIGDEAklLPSNTGAGYILRRLIRR 312
Cdd:COG0013 233 RIAAVLQGVHSNYETDLFRPLIEAAAELTGVKYGADEEDDVSLRVIADHIRAVAFLIADGV--LPSNEGRGYVLRRILRR 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 313 AVRHARTLGLNKDQILGVATIYIDEYSESYENLAKNRKFVLTELEREITRFESTLENGMKEFRKILDKTSAAGKKEIEGK 392
Cdd:COG0013 311 AVRHGRLLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKLKAAGGKVLSGE 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 393 DAFFLYDTFGFPVELTVELADEEGFTVDEEGFKASMEEQKQKARENQNFSANLSTGTGLFDNLDESVATEFLGYEKLECD 472
Cdd:COG0013 391 DAFKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAAAKFSGDAAVDGVWRELLEEGGPTEFVGYDTLEAE 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 473 GTVAVIAGADALVTELTEGQQGTIITDKTTFYGTMGGQVGDIGEILGsNGAKFEVTEAVKVAGGRTAHVGKVVSGSFKVS 552
Cdd:COG0013 471 AKVLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEG-DGGVFEVTDTQKPPGGLIVHIGKVEEGELKVG 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 553 DKVTLSVDAENRAKTCRNHSATHLLQKALQMVLGDGVEQAGSYQDPDKTRFDFSYHQAMTADEIKKVEDIVNSKILEALP 632
Cdd:COG0013 550 DTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLP 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 633 VVTKEMSIEDAKKTGAMALFGEKYGETVRVVNMGDFSIELCGGTHVANTSHIGLFKILSESGVAAGVRRIEALTGDNARA 712
Cdd:COG0013 630 VETREMPLDEAKALGAMALFGEKYGDEVRVVSIGDFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALE 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 713 YYKNVEANLGEAAKTLKTTPADLVDHIKKLQEELKNLRSENESLKSKEAQAALGDVMDQVLEIKGVKLLATSVKGVDMNG 792
Cdd:COG0013 710 YLREQEALLKELAELLKAPPEELPERVEALLEELKELEKELEQLKAKLASAAADDLLAQAEEIGGVKVLAARVEGVDAKD 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 793 LRDLGDQMKTKLGEGVVVLISEADGKVNLVTMATDGAMAKGAHAGNLVKAIAPKVGGGGGGRPNMAQAGGKNPAGIQDAL 872
Cdd:COG0013 790 LRDLADDLKDKLGSGVVVLASVADGKVSLVAGVTKDLVKKGLKAGDLVKEVAKIVGGGGGGRPDMAQAGGKDPSKLDEAL 869
|
890
....*....|.
gi 503045638 873 AEAKTVLLSQI 883
Cdd:COG0013 870 AAVKEWLAEKL 880
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
8-862 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 814.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 8 ELREAWKQFYKDRGHVDCGAVSLVSDGSTGVMFNVAGMQPLMPYLLGKKHPMGTRLCNVQGCVRTNDIDSVGDKS-HGTF 86
Cdd:TIGR00344 1 EIRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPSNRLTNAQPCIRLNDLENVGRTArHHTL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 87 FEMMGSWSLGDYFKKERCQWSFELLTQLFGFDADHLAATVFagdenaPRDEEGAKYRIESGFKPENIYYLPAEDNWWGLE 166
Cdd:TIGR00344 81 FEMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVY------EDDEEAYKIWEKIGIPADRIIKCDAKDNFWDMG 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 167 YGPCGPDSEMFYVKDMpdcGPNCGPGCHCGKYTEIGNDVFMQYEKHHDGHLTPLTQKNVDTGWGLERILAFLNGVDDVYK 246
Cdd:TIGR00344 155 DGPCGPCTEIYYDFVG---GKPGEPLEENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVAVLQGVPTNYD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 247 IDLHAPVIAYIEKESGLKYESDE---------KTTRSMRILADHTRTSVMLIGDeaKLLPSNTGAGYILRRLIRRAVRHA 317
Cdd:TIGR00344 232 TDIFLPLIEKIEEITGVKYDSNNagimdekrvEDLRSLRVIADHTRAIAFMLAD--GVVPSNEGRGYVLRRLIRRALRHG 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 318 RTLGLNKDQILGVATIYIDEYSESYENLAKNRKFVLTELEREITRFESTLENGMKEFRKILDKTsaaGKKEIEGKDAFFL 397
Cdd:TIGR00344 310 KKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKT---GKKELDGEDAFKL 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 398 YDTFGFPVELTVELADEEGFTVDEEGFKASMEEQKQKARENQNFSANlstgtglFDNL-DESVATEFLGYEKLECDGTVA 476
Cdd:TIGR00344 387 YDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQFQEQ-------EIALvNVYPATEFLGYDDLEFEAKVI 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 477 VIAGADALVTELTEGQQGTIITDKTTFYGTMGGQVGDIGEILGsNGAKFEVtEAVKVAGGRTAHVGKVVSGSFKVSDKVT 556
Cdd:TIGR00344 460 GLFDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIA-NDGKFRV-VDVQKPNGVVFHFGEVEGGSLKVGDKVI 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 557 LSVDAENRAKTCRNHSATHLLQKALQMVLGDGVEQAGSYQDPDKTRFDFSYHQAMTADEIKKVEDIVNSKILEALPVVTK 636
Cdd:TIGR00344 538 AVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREELEEIEDLANEQILANIPIKVI 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 637 EMSIEDAKKTGAMALFGEKY--GETVRVVNMGDFSIELCGGTHVANTSHIGLFKILSESGVAAGVRRIEALTGDNARAYY 714
Cdd:TIGR00344 618 FMDLDEAKRKGAFALFGEKYvpGEKVRVVSVGDFSVELCGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYL 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 715 KNVEANLGEAAKTLKTTPADLVDHIKKLQEELKNLRSENESLKSKEAQAALGDVMDQVLEIKGVKLLATSVKGVDMNGLR 794
Cdd:TIGR00344 698 NEQEDKLKELADILKVTPNELPKKVERFFEEWKALQKELESLKLKIADQKIDELKDKAETINGVKVLVEVVDAKDMKSLK 777
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 503045638 795 DLGDQMKTKLGEGVVVLISEADGKVNLVTMATDGAMAKGAHAGNLVKAIAPKVGGGGGGRPNMAQAGG 862
Cdd:TIGR00344 778 TMADRLKSKLGSAIYVLASFAEGKVKLVCGVSNDVLTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
1-881 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 751.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 1 MKQFTAQELREAWKQFYKDRGHVDCGAVSLVSDGSTGVMFNVAGMQPLMPYLLGKKHPMG-----TRLCNVQGCVRT--- 72
Cdd:PLN02900 8 EKEWPGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTplrklPRATNTQKCIRAggk 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 73 -NDIDSVG-DKSHGTFFEMMGSWSLGDYFKKERCQWSFELLTQLFGFDADHLAATVFAGDENAPRDEEGakYRIESGFKP 150
Cdd:PLN02900 88 hNDLDDVGkDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEKQAPDDEA--RAIWLDYLP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 151 EN-IYYLPAEDNWWGL-EYGPCGPDSEMFY----------VKDMPDcgPNCgpgchcgkyTEIGNDVFMQYEKHHDGHLT 218
Cdd:PLN02900 166 EErVLPFGCKDNFWEMgDTGPCGPCSEIHYdrigerdaadLVNNDD--PRF---------IEIWNLVFIQFNREADGSLK 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 219 PLTQKNVDTGWGLERILAFLNGVDDVYKIDLHAPVIAYIEKESGLKY-------ESDEKTTRSMRILADHTRTSVMLIGD 291
Cdd:PLN02900 235 PLPAKHVDTGMGLERLASILQNKPSNYDTDLFMPIFDAIQEATGARPyagkvgaEDDDRVDMAYRVVADHIRTLSFAIAD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 292 EAklLPSNTGAGYILRRLIRRAVRHARTLGLNKDQIL-GVATIYIDEYSESYENLAKNRKFVLTELEREITRFESTLENG 370
Cdd:PLN02900 315 GV--VPSNEGRGYVLRRLLRRAVRYGRLLLGAEEGFFpALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKG 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 371 MKEFRKILDKTSAAGKKEIEGKDAFFLYDTFGFPVELTVELADEEGFTVDEEGFKASMEEQKQKARENQNFSANLS---- 446
Cdd:PLN02900 393 IEKFKKALAAAKANGGPVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRAAHLKAGGGAiela 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 447 -TGTGLFDNLDESVATEFLGYEKLEC-DGTVAVIAGADALVTELTEGQQGTIITDKTTFYGTMGGQVGDIGEILGSNGAK 524
Cdd:PLN02900 473 aEATSWLQKQGVAATDDFLKYDWLSDhEAVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEGSGGAV 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 525 FEVTEaVKVAGGRTAHVGKVVSGSFKVSDKVTLSVDAENRAKTCRNHSATHLLQKALQMVLGDGVEQAGSYQDPDKTRFD 604
Cdd:PLN02900 553 VEVSD-VQKAGGFVLHIGTVTEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFD 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 605 FSYHQAMTADEIKKVEDIVNSKILEALPVVTKEMSIEDAKKT-GAMALFGEKYGETVRVVNMGD-FSIELCGGTHVANTS 682
Cdd:PLN02900 632 FSHGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRInGLRAVFGEKYPDPVRVVSVGGvYSMELCGGTHVSNTA 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 683 HIGLFKILSESGVAAGVRRIEALTGDNARAYYKNVEANLGEAAKTLKTT------------------------PADLVDH 738
Cdd:PLN02900 712 EAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDSALKVEgsdlekkvaslksrvdaavipaakKEEIRAR 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 739 IKKLQEELKNLRSENESLKSKEAQAALGDVMDQVLEIKGVKLLATSVKGVDMNGLRDLGDQMKTKLGEGVVVLIS--EAD 816
Cdd:PLN02900 792 VSALQKELRAAQKEAAALRAKLAVAKATELASKALSAGKSVLVARLDVGVDAAALKEAAEKVIAKLGDPAAVVLSsdEEK 871
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 503045638 817 GKVNLVTMATDGAMAKGAHAGNLVKAIAPKVGGGGGGRPNMAQAGGKNPAGIQDALAEAKTVLLS 881
Cdd:PLN02900 872 GKVSLVAAVPPGVVKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALEKARAFAVA 936
|
|
| PRK01584 |
PRK01584 |
alanyl-tRNA synthetase; Provisional |
5-708 |
0e+00 |
|
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain] Cd Length: 594 Bit Score: 639.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 5 TAQELREAWKQFYKDRGHVDCGAVSLVSDGSTGVMFNVAGMQPLMPYLLGKKHPMGTRLCNVQGCVRTNDIDSVGDKSHG 84
Cdd:PRK01584 2 TLDELRKKYIDFFKSKGHVEIAGKSLIPENDPTVLFTTAGMHPLVPYLLGEPHPSGTRLVDVQKCLRTGDIDEVGDLSHL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 85 TFFEMMGSWSLGDYFKKERCQWSFELLT--QLFGFDADHLAATVFAGDENAPRDEEGAKYRIESGFKPENIYYLPAEDNW 162
Cdd:PRK01584 82 TFFEMLGNWSLGAYFKEESIKYSFEFLTspDYLNIPKDKLYVTVFEGDEEIPRDEETASVWESLGIPKDRIFYLSREHNW 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 163 WGL--EYGPCGPDSEMFYVKDMPDCGPNCGPGCHCGKYTEIGNDVFMQYEKHHDGHLTPLTQKNVDTGWGLERILAFLNG 240
Cdd:PRK01584 162 WGPvgETGPCGPDTEIFVDTGKPKCSVNCRPTCSCGKYFEIWNNVFMQYNKDEDGNYEELKRKCVDTGMGIERTIAFLQG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 241 VDDVYKIDLHAPVIAYIEKESGLKYESDEKTTRSMRILADHTRTSVMLIGDEAKLLPSNTGAGYILRRLIRRAVRHARTL 320
Cdd:PRK01584 242 KSSVYDTEAFTPIIKRIEKISGKIYGQNEEDDRSIRIIADHIRAACFILGDPFVVLPSNVGQGYVLRRLIRRSIRHAKKL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 321 GLNKDQILGVATIYIDEYSESYENLAKNRKFVLTELEREITRFESTLENGMKEFRKILDKTSAagKKEIEGKDAFFLYDT 400
Cdd:PRK01584 322 GIESHFLADLVDSVEEIYGSFYPELTEKKDFIKEELNKEEEKFFKTLRKGEQEFIKLIPNLGS--SKIIPGDIAFKLYDT 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 401 FGFPVELTVELADEEGFTVDEEGFKASMEEQKQKARenqnfsanlstgtglfdnldesvateflgyeklecdgtvaviAG 480
Cdd:PRK01584 400 YGFPYEITEELASEYGFTVDREGFDEHFKKHQKVSK------------------------------------------KG 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 481 ADalvteltegqqgtiitdkttfygtmggqvgdigeilgsngakfevteavkvaggrtahvgKVVSGSFkvsdkvtlsvd 560
Cdd:PRK01584 438 AD------------------------------------------------------------KVFKGGL----------- 446
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 561 AENRAKTCRNHSATHLLQKALQMVLGDGVEQAGSYQDPDKTRFDFSYHQAMTADEIKKVEDIVNSKILEALPVVTKEMSI 640
Cdd:PRK01584 447 ADHSYETTKLHTATHLLHKALRLVLGDHVRQKGSNITAERLRFDFSHPEKMTDDEIKKVEDIVNLQIKNDLSVKKEVMSL 526
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 503045638 641 EDAKKTGAMALFGEKYGETVRVVNMGDFSIELCGGTHVANTSHIGLFKILSESGVAAGVRRIEALTGD 708
Cdd:PRK01584 527 EEAREKGAMALFGEKYEDIVKVYEIDGFSKEVCGGPHVENTGELGTFKIQKEQSSSSGVRRIRAILID 594
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
8-562 |
2.33e-162 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 484.86 E-value: 2.33e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 8 ELREAWKQFYKDRGHVDCGAVSLVSDGSTGVMFNVAGMQPLMPYLLGKKH-PMGTRLCNVQGCVRTNDIDSVG-DKSHGT 85
Cdd:pfam01411 1 EIRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVAkPPYNRATNSQKCIRAGDLENVGrTGRHHT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 86 FFEMMGSWSLGDYFKKERCQWSFELLTQLFGFDADHLAATVFAGDENAprdeeGAKYRIESGFKPENIYYLPAEDNWWGL 165
Cdd:pfam01411 81 FFEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDDEA-----GPIWEKIVGGPEERILRFGDKDNFWEM 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 166 -EYGPCGPDSEMFYvkdmpDCGPNCGPGCHCGK-------YTEIGNDVFMQYEKHHDGHLTPLTQKNVDTGWGLERILAF 237
Cdd:pfam01411 156 gDTGPCGPCSEIDY-----DRGEEIGGWDSGGTptadddrFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGLERLVAV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 238 LNGVDDVYKIDLHAPVIAYIEKESGLKYESDEKTTRSMRILADHTRTSVMLIGDeaKLLPSNTGAGYILRRLIRRAVRHA 317
Cdd:pfam01411 231 LQDVRSNYDTDVFIPVIELIEEISGARYYTVDETDEAYRVIADHTRALTFALAD--GVVPSNEGRGYVLRRILRRAVRHA 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 318 RTLGLNKDQILGVATIYIDEYSESYENLAKNRKFVLTELEREITRFESTLENGMKEFRKILdKTSAAGKKEIEGKDAFFL 397
Cdd:pfam01411 309 KKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLI-AKLKKGKKTLPGEDAFKL 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 398 YDTFGFPVELTVELADEEGFTVDEEGFKASMEEQKQKARENQNFSANLSTGTGLfdnLDESVATEFLGYEKLECDGTVAV 477
Cdd:pfam01411 388 YDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKGEKLDVSAL---KELPATTEFLGYDDLESEAKILA 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 478 IAGADALVTELTEGQQGTIITDKTTFYGTMGGQVGDIGEILGsNGAKFEVTEaVKVAGGRTAHVGKVVSGSFKVSDKVTL 557
Cdd:pfam01411 465 LPKDGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIG-DGGEFRVTD-VQKYGGVVVHKGKLESGKLKVGDKVIA 542
|
....*
gi 503045638 558 SVDAE 562
Cdd:pfam01411 543 VIDED 547
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
6-241 |
1.83e-75 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 246.12 E-value: 1.83e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 6 AQELREAWKQFYKDRGHVDCGAVSLVSDGSTGVMFNVAGMQPLMPYLLGKKHPMGTRLCNVQGCVRTNDIDSVG-DKSHG 84
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPANRLVNSQKCIRAGDIDNVGkTGRHH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 85 TFFEMMGSWSLGDYFKKERCQWSFELLTQLFGFDADHLAATVFAGDenaprDEEGAKYRIESGFKPENIYYLPAEDNWWG 164
Cdd:cd00673 81 TFFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGD-----DEEEAIWWWKIGLPGIRIERIGFKDNFWE 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 503045638 165 L-EYGPCGPDSEMFYVKdMPDCGPNCGPGCHCGKYTEIGNDVFMQYEKHHDGHLTPLTQKNVDTGWGLERILAFLNGV 241
Cdd:cd00673 156 MgGNGPCGPCSEIFYDR-GEERDAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERLVWVLQGV 232
|
|
| AlaX |
COG2872 |
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ... |
481-703 |
6.73e-34 |
|
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain] Cd Length: 238 Bit Score: 130.31 E-value: 6.73e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 481 ADALVTELTEgqQGTIITDKTTFYGTMGGQVGDIGEILGsNGAKFEVTEAVKvAGGRTAHVgkvVSGS--FKVSDKVTLS 558
Cdd:COG2872 15 FEATVTAVTE--EGGVVLDRTAFYPTGGGQPGDTGTLVW-DGKEIRVVDVRK-EDGEIVHV---LEGAplPEVGDEVTGE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 559 VDAENRAKTCRNHSATHLLQKALQMVLGDGVeqAGSYQDPDKTRFDFSYhQAMTADEIKKVEDIVNSKILEALPVVTKEM 638
Cdd:COG2872 88 IDWERRYRHMRLHTALHLLSAVVYREYGAPV--TGGQIGEDRARIDFDL-PEFDEEDLEEIEAEANELIAADLPVRIYWI 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 503045638 639 SIEDA------KKTgAMALFGEKYGEtVRVVNMGDFSIELCGGTHVANTSHIGLFKILS-ESgVAAGVRRIE 703
Cdd:COG2872 165 TREELeaipglVRT-MSVLPPPGVGR-VRIVEIGGVDLQPCGGTHVANTGEIGRIKITKiEK-KGKGNRRVY 233
|
|
| a_tRNA_ed_AlaXM |
NF040865 |
alanyl-tRNA editing protein AlaXM; |
481-703 |
8.01e-30 |
|
alanyl-tRNA editing protein AlaXM;
Pssm-ID: 468802 [Multi-domain] Cd Length: 234 Bit Score: 118.48 E-value: 8.01e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 481 ADALVTELTEGQqgtIITDKTTFYGTMGGQVGDIGeILGSNGAKFEVTEAVKvAGGRTAHVGKVVSGsFKVSDKVTLSVD 560
Cdd:NF040865 14 FDATVVRVKGNG---VVLDRTAFYPTGGGQPHDTG-TLVRDDKEFRVVDVRK-EGGEIAHVVDRAPG-LKPGDKVKGEID 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 561 AENRAKTCRNHSATHLLQKALQMVLGDGVeqAGSYQDPDKTRFDFSYhQAMTADEIKKVEDIVNSKILEALPVVTKEMSI 640
Cdd:NF040865 88 WDRRYRLMRYHTASHILSAVLYREYGALI--TGGQISPDKARVDFSL-ENFDRELLEEIIEEANEIIAEGIEVKIYWLPR 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 503045638 641 EDAKKTGAMALFGEKYG---ETVRVVNMGDFSIELCGGTHVANTSHIGLFKILSESGVAAGVRRIE 703
Cdd:NF040865 165 EEALKIPGLVRLAKRLPpeiEEVRIVEIEGVDIQADGGTHVKNTGEIGEIKILKRENKGKGNKRLY 230
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
660-702 |
6.37e-22 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 88.98 E-value: 6.37e-22
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 503045638 660 VRVVNMGDFSIELCGGTHVANTSHIGLFKILSESGVAAGVRRI 702
Cdd:smart00863 1 VRVVSIGDFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| tRNA_SAD |
pfam07973 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of ... |
660-702 |
1.42e-20 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 429764 [Multi-domain] Cd Length: 43 Bit Score: 85.19 E-value: 1.42e-20
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 503045638 660 VRVVNMGDFSIELCGGTHVANTSHIGLFKILSESGVAAGVRRI 702
Cdd:pfam07973 1 VRVVSIGDFDVDLCGGTHVPNTGEIGAFKILKGESKNKGLRRI 43
|
|
| PLN02961 |
PLN02961 |
alanine-tRNA ligase |
496-689 |
2.27e-16 |
|
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain] Cd Length: 223 Bit Score: 78.97 E-value: 2.27e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 496 IITDKTTFYGTMGGQVGDIGEILGSNG-AKFEVTeAVKVAGGRTAHVGkVVSGS-------FKVSDKVTLSVDAENRAKT 567
Cdd:PLN02961 5 LVLDRTIFHPQGGGQPSDTGRIVISGGdTKFSVQ-DVRRKDGVVYHYG-VFEGSnpesaspFEAGDEVTVTVDESRRKLH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 568 CRNHSATHLLQKALQMVLGDGVEQAGSYQDPDKTRFDfsYHQAMTADEIKKVEDIVNSK----ILEALPVVTKEMSIEDA 643
Cdd:PLN02961 83 SRLHSAGHLLDVCMARVGLGPLEPGKGYHFPDGPFVE--YKGKIPQGELDSKQDELEAEanelIAEGGKVSAAVLPYDEA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 503045638 644 KKT--GAMALFGEKyGETVRVVNMGDFSIELCGGTHVANTSHIGLFKI 689
Cdd:PLN02961 161 AELcgGSLPDYIAK-DSTPRIVKIGDSPGCPCGGTHVADVSEITSVKV 207
|
|
| DHHA1 |
pfam02272 |
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called ... |
739-879 |
3.60e-15 |
|
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA1 for DHH associated domain. This domain is diagnostic of DHH subfamily 1 members. This domains is also found in alanyl tRNA synthetase, suggesting that this domain may have an RNA binding function. The domain is about 60 residues long and contains a conserved GG motif.
Pssm-ID: 396724 [Multi-domain] Cd Length: 139 Bit Score: 73.24 E-value: 3.60e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 739 IKKLQEELKNLRSENESLKSKEAQAALGDVMDQVLEIKGVKLLATSVK-GVDMNGLRDLGDQMKTKLGEGVVVLISEADG 817
Cdd:pfam02272 1 LESLNEELKELEKELEELKEALALLKAKELLEKAEEINGVKVLVAEVGeGWDAGALGIAADRLKKKLGDPVIVLVAKEDG 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 503045638 818 -KVNLVTMATDGamaKGAHAGNLVKAIAPKVGGGGGGRPnMAQAGGKNPAGIQDALAEAKTVL 879
Cdd:pfam02272 81 dKVKVSARSSKD---KGVDAGELLKEVAAILGGGGGGHD-LAAGAGIDAEKLDEALELLEEAI 139
|
|
| ThrS |
COG0441 |
Threonyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Threonyl-tRNA ... |
570-694 |
2.86e-09 |
|
Threonyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Threonyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440210 [Multi-domain] Cd Length: 639 Bit Score: 60.82 E-value: 2.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 570 NHSATHLLQKALQMV-----LGDG--VEQaGSYqdpdktrFDFSYHQAMTADEIKKVEDIVNSKILEALPVVTKEMSIED 642
Cdd:COG0441 72 RHSAAHLLAQAVKRLypdakLTIGpvIEN-GFY-------YDFDLERPFTPEDLEKIEKEMKEIIKEDLPIEREEVSREE 143
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 503045638 643 AKKTgaMALFGEKY----------GETVRVVNMGDFsIELCGGTHVANTSHIGLFKILSESG 694
Cdd:COG0441 144 AIEL--FKEKGEPYkveliedipeDEEISLYRQGEF-VDLCRGPHVPSTGKIKAFKLLSVAG 202
|
|
| PRK12444 |
PRK12444 |
threonyl-tRNA synthetase; Reviewed |
542-694 |
6.83e-07 |
|
threonyl-tRNA synthetase; Reviewed
Pssm-ID: 183530 [Multi-domain] Cd Length: 639 Bit Score: 53.21 E-value: 6.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 542 GKVVSGSFKVSDKVTLSV---DAENRAKTCRnHSATHLLQKALQMVLGD------GVEQAGSYqdpdktrFDFSYHQAMT 612
Cdd:PRK12444 46 DKLYDLRRNLEEDAEVEIitiDSNEGVEIAR-HSAAHILAQAVKRLYGDvnlgvgPVIENGFY-------YDMDLPSSVN 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503045638 613 ADEIKKVEDIVNSKILEALPVVTKEMSIEDAKKtgamaLFGEKY-------------GETVRVVNMGDFsIELCGGTHVA 679
Cdd:PRK12444 118 VEDLRKIEKEMKKIINENIKIERVEVSREEAAK-----LFQEMNdrlklelleaipsGESITLYKQGEF-VDLCRGPHLP 191
|
170
....*....|....*
gi 503045638 680 NTSHIGLFKILSESG 694
Cdd:PRK12444 192 STGYLKAFQLTHVSG 206
|
|
| |
