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Conserved domains on  [gi|503606329|ref|WP_013840405|]
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uracil-xanthine permease family protein [Desulforamulus ruminis]

Protein Classification

uracil-xanthine permease family protein( domain architecture ID 10789278)

uracil-xanthine permease family protein similar to xanthine permease and uracil permease, which mediate the transport of xanthine and uracil, respectively

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
UraA COG2233
Xanthine/uracil permease [Nucleotide transport and metabolism]; Xanthine/uracil permease is ...
2-432 2.05e-72

Xanthine/uracil permease [Nucleotide transport and metabolism]; Xanthine/uracil permease is part of the Pathway/BioSystem: Pyrimidine degradation


:

Pssm-ID: 441834  Cd Length: 439  Bit Score: 234.25  E-value: 2.05e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329   2 NKINFKYGLDDIPPLTELLLFGLQWLAIIVPIIIIIGKAIVGLHFSDPLDQVVYLQKLFFVSAVSLLAQVL-WGHRLPLI 80
Cdd:COG2233    5 ASSGLVYGVDERPPLGQTLLLGLQHVLAMFGATVLVPLIVGGALGLSAAQTALLISAALFVSGIGTLLQLLgTGGRLPIV 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  81 IGPAAVLLVG-IAASQGSSTSTIYSSILISGMILLLLSatGLFAKVKKLFTPQVIATILILIALTLTPMIINLI---FAS 156
Cdd:COG2233   85 LGSSFAFIAPiIAIGAAYGLAAALGGIIVAGLVYILLG--LLIKRIRRLFPPVVTGTVVMLIGLSLAPVAINMAaggPGA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 157 QQVAPVQNLCFVFIFVLGMFWANQRLTGLWKTTLIIWAVIIGTALYMLLFP-QYTGISYHQNFSPISSFFRHVSldfSLD 235
Cdd:COG2233  163 PDFGSPQNLLLALVTLAVILLLSVFGKGFLRRISILIGIVVGYIVALLLGMvDFSPVAEAPWFALPTPFPFGLP---TFD 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 236 PSVLISFLICFLALSINDLGSIQSIGEIIRPDNMEKRITRGVSFTGLGNILSGLFGVIGPVNFSLSPGVIASTGVASRFT 315
Cdd:COG2233  240 LGAILTMLPVALVTIAETIGDILAVGEITGRDITDPRLGRGLLGDGLATMLAGLFGGFPNTTYSENIGVIALTGVYSRYV 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 316 LIPTAFGLLLLSFLPSTIAFIGSIPSAVTGSVLIYIMCAQISSGLLVAFNTTGGfKFENGLIMGLPLMLSIIISFLpPNI 395
Cdd:COG2233  320 VAVAAVILILLGLFPKLGALIATIPSPVLGGATIVLFGMIAASGIRILVNVDFS-NPRNLLIVAVSLGLGLGVTGV-PGA 397
                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 503606329 396 ANSFPSSLRPIMGNGFVIGVLSVLILENVIYRRRNSE 432
Cdd:COG2233  398 LATLPATLGPLFLSGIALGALVAILLNLLLPGKKEEE 434
 
Name Accession Description Interval E-value
UraA COG2233
Xanthine/uracil permease [Nucleotide transport and metabolism]; Xanthine/uracil permease is ...
2-432 2.05e-72

Xanthine/uracil permease [Nucleotide transport and metabolism]; Xanthine/uracil permease is part of the Pathway/BioSystem: Pyrimidine degradation


Pssm-ID: 441834  Cd Length: 439  Bit Score: 234.25  E-value: 2.05e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329   2 NKINFKYGLDDIPPLTELLLFGLQWLAIIVPIIIIIGKAIVGLHFSDPLDQVVYLQKLFFVSAVSLLAQVL-WGHRLPLI 80
Cdd:COG2233    5 ASSGLVYGVDERPPLGQTLLLGLQHVLAMFGATVLVPLIVGGALGLSAAQTALLISAALFVSGIGTLLQLLgTGGRLPIV 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  81 IGPAAVLLVG-IAASQGSSTSTIYSSILISGMILLLLSatGLFAKVKKLFTPQVIATILILIALTLTPMIINLI---FAS 156
Cdd:COG2233   85 LGSSFAFIAPiIAIGAAYGLAAALGGIIVAGLVYILLG--LLIKRIRRLFPPVVTGTVVMLIGLSLAPVAINMAaggPGA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 157 QQVAPVQNLCFVFIFVLGMFWANQRLTGLWKTTLIIWAVIIGTALYMLLFP-QYTGISYHQNFSPISSFFRHVSldfSLD 235
Cdd:COG2233  163 PDFGSPQNLLLALVTLAVILLLSVFGKGFLRRISILIGIVVGYIVALLLGMvDFSPVAEAPWFALPTPFPFGLP---TFD 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 236 PSVLISFLICFLALSINDLGSIQSIGEIIRPDNMEKRITRGVSFTGLGNILSGLFGVIGPVNFSLSPGVIASTGVASRFT 315
Cdd:COG2233  240 LGAILTMLPVALVTIAETIGDILAVGEITGRDITDPRLGRGLLGDGLATMLAGLFGGFPNTTYSENIGVIALTGVYSRYV 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 316 LIPTAFGLLLLSFLPSTIAFIGSIPSAVTGSVLIYIMCAQISSGLLVAFNTTGGfKFENGLIMGLPLMLSIIISFLpPNI 395
Cdd:COG2233  320 VAVAAVILILLGLFPKLGALIATIPSPVLGGATIVLFGMIAASGIRILVNVDFS-NPRNLLIVAVSLGLGLGVTGV-PGA 397
                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 503606329 396 ANSFPSSLRPIMGNGFVIGVLSVLILENVIYRRRNSE 432
Cdd:COG2233  398 LATLPATLGPLFLSGIALGALVAILLNLLLPGKKEEE 434
PRK11412 PRK11412
uracil/xanthine transporter;
18-425 1.79e-26

uracil/xanthine transporter;


Pssm-ID: 183124  Cd Length: 433  Bit Score: 110.64  E-value: 1.79e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  18 ELLLFGLQWLAIIVPIIIIIGKAIVGLHFSDPLDQVVYLQKLFFVSAVSLLAQVLWGHRLPLIIGPA-----AVLLVGIA 92
Cdd:PRK11412   9 ESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLLTLTQYAFLATALACFAQAFCGHRRAIMEGPGglwwgTILTITLG 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  93 ASQ-----GSSTSTIYSSILISGMILLLLSATGLFAKVKKLFTPQVIATILILIALTLTPM----IINLIFASQQVAPVQ 163
Cdd:PRK11412  89 EASrgtpiNDIATSLAVGIALSGVVTILIGFSGLGHRLARLFTPMVMVVFMLLLGAQLTTIffkgMLGLPFGIADPNGKI 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 164 NL------CFVFIFVLGMFWanqRLTGLWKTTLIIWAVIIGTALYMLLFPqytgiSYHQNFSPISSFFRHVSLDFSLDPS 237
Cdd:PRK11412 169 QLppfglsVAVMCLVLAMII---FLPQRIARYSLLVGTIVGWILWAFCFP-----SSHSLSGELHWQWFPLGSGGALEPG 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 238 VLISFLICFLALSINDLGSIQSIGEIIRPDNME-KRITRGVSFTGLGNILSGLFGVIGPVNFSLSPGVIASTGVASRFTL 316
Cdd:PRK11412 241 IILTAVITGLVNISNTYGAIRGTDVFYPQQGAGnTRYRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYRRRSF 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 317 IPTAFGLLLLSFLPSTIAFIGSIPSAVTGSVLIYIMCAQISSGLLVAFNTTggFKFENGLIMGLPLMLSIIISFLPPNIA 396
Cdd:PRK11412 321 IYGSVMCLLVALIPALTRLFCSIPLPVSSAVMLVSYLPLLGSALVFSQQIT--FTARNIYRLALPLFVGIFLMALPPVYL 398
                        410       420
                 ....*....|....*....|....*....
gi 503606329 397 NSFPSSLRPIMGNGFVIGVLSVLILENVI 425
Cdd:PRK11412 399 QDLPLTLRPLLSNGLLVGILLAVLMENLI 427
NCS2_1 NF037981
purine/pyrimidine permease; Proteins of this family usually have 14 transmembrane domains. ...
19-422 6.75e-25

purine/pyrimidine permease; Proteins of this family usually have 14 transmembrane domains. They belong to the NSC2 superfamily transporters. They are specific purine and/or pyrimidine permeases.


Pssm-ID: 468300  Cd Length: 419  Bit Score: 105.83  E-value: 6.75e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  19 LLLFGLQWLAIIVPIIIIIGKAIVGLHFSDPLDQVVYLQKLFFVSAVSLLAQVLWGHRLPLIIGPAAVL---------LV 89
Cdd:NF037981   3 LFLGGLQWMAFMIAASIAAPIAIADLFHLNPAETAGLVQRTIFVLGIAGLLQALFGHRLPINEGPAGLWwgvftiyagLV 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  90 GIA-ASQGSSTSTIYSSILISGMILLLLSATGLFAKVKKLFTPQVIATILILIALTLTPMIINLIF----ASQQVAPVQn 164
Cdd:NF037981  83 GTLySTNIETLQALQGAMLVSGVFFFLLSVTGLIDKLAVLFTPVVTFIYLLLLVLQLSGSFIKGMMgigyEGNEVDPLV- 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 165 LCFVFIFVLGMFWANQRLTGLWKTTLIIWAVIIGTALYMLLFPQYTGISYHQNFSPISSFFRHVSLDFslDPSVLI-SFL 243
Cdd:NF037981 162 FLLSLVVIILTFYFSRHKIKWIRQYSILLSLAGGWLLFALFGKAPAIAHTGGSIISLPELFVFGPPVF--DSGLIVtSFF 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 244 ICFLaLSINDLGSIQSIGEIIRPDNME---KRITRGVSFTGLGNILSGLFGVIGPVNFSLSPGVIASTGVASRFTLIPTA 320
Cdd:NF037981 240 ITLL-LIANMLASIRVMEEVLKKFGKIevsERYRQAGFASGINQLLGGLFSAIGSVPISGAAGFVATTGIPSLKPFIIGS 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 321 FGLLLLSFLPSTIAFIGSIPSAVTGSVLIYIMCAQISsgllVAFNttgGFKFENG-----LIMGLPLMLSIIISFLPPNI 395
Cdd:NF037981 319 LLVVIISLFPPLMNIFASLPAPVGYAVTFVVFSKMVG----LAFG---ELDKEENkerarFVIGIALLAGVGAMFVPASA 391
                        410       420
                 ....*....|....*....|....*..
gi 503606329 396 ANSFPSSLRPIMGNGFVIGVLSVLILE 422
Cdd:NF037981 392 LSGLPPVVASLLNNGLILGTLIAIAVE 418
Xan_ur_permease pfam00860
Permease family; This family includes permeases for diverse substrates such as xanthine, ...
18-393 2.24e-24

Permease family; This family includes permeases for diverse substrates such as xanthine, uracil and vitamin C. However many members of this family are functionally uncharacterized and may transport other substrates. Members of this family have ten predicted transmembrane helices.


Pssm-ID: 395690 [Multi-domain]  Cd Length: 389  Bit Score: 103.92  E-value: 2.24e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329   18 ELLLFGLQWLAIIVPIIIIIGKaIVGLHFSDPLDQVVYLQKL-FFVSAVSLLAQVLW-GHRLPLIIGPA-----AVLLVG 90
Cdd:pfam00860   2 QLLLLGLQHLLAMFAATIVVPL-LVGDALGLGAEDLAQLISAtFLASGIGTLLQTLIfGIRLPIYLGSSfafvtALMIAL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329   91 IAASQGSSTSTIYSSILISGMILLLLSATGLFAKVKKLFTPQVIATILILIALTLTPMIIN------LIFASQQVAPVQN 164
Cdd:pfam00860  81 GLADWGIALAGLFGAVLVAGVLFTLISFTGLRGRLARLFPPVVTGPVVLLIGLSLAPIAVKgagggwAIADGLTVGLLDL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  165 LCFVFIFVLGMFWANQRLTGLWKTTLIIWAVIIGTALYMLLFpqytgisyHQNFSPISSFFRHVSLDF-------SLDPS 237
Cdd:pfam00860 161 LGLAVVVLAVILLLSVFLKGFFRQGPILIGIIAGWLLALFMG--------IVNFSPEVMDAPWFQLPHpfpfgtpLFNPG 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  238 VLISFLICFLALSINDLGSIQSIGEII-RPDNMEKRITRGVSFTGLGNILSGLFGVIGPVNFSLSPGVIASTGVASRFTL 316
Cdd:pfam00860 233 LILTMLAVALVAIVESTGDIRAVAKVSgRDLKPKPDLRRGLLADGLATLLSGLFGAFPTTTYAENIGVVALTKVYSRRVG 312
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 503606329  317 IPTAFGLLLLSFLPSTIAFIGSIPSAVTGSVLIYIMCAQISSGlLVAFNTTGGFKFENGLIMGLPLMLSIIISFLPP 393
Cdd:pfam00860 313 VTAGVILILLGLIPKFAALFSSIPSPVLGGVMLVMFGMIAGSG-VSNLITVDLDSARNLLIIAVSLVLGLGISTVPE 388
 
Name Accession Description Interval E-value
UraA COG2233
Xanthine/uracil permease [Nucleotide transport and metabolism]; Xanthine/uracil permease is ...
2-432 2.05e-72

Xanthine/uracil permease [Nucleotide transport and metabolism]; Xanthine/uracil permease is part of the Pathway/BioSystem: Pyrimidine degradation


Pssm-ID: 441834  Cd Length: 439  Bit Score: 234.25  E-value: 2.05e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329   2 NKINFKYGLDDIPPLTELLLFGLQWLAIIVPIIIIIGKAIVGLHFSDPLDQVVYLQKLFFVSAVSLLAQVL-WGHRLPLI 80
Cdd:COG2233    5 ASSGLVYGVDERPPLGQTLLLGLQHVLAMFGATVLVPLIVGGALGLSAAQTALLISAALFVSGIGTLLQLLgTGGRLPIV 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  81 IGPAAVLLVG-IAASQGSSTSTIYSSILISGMILLLLSatGLFAKVKKLFTPQVIATILILIALTLTPMIINLI---FAS 156
Cdd:COG2233   85 LGSSFAFIAPiIAIGAAYGLAAALGGIIVAGLVYILLG--LLIKRIRRLFPPVVTGTVVMLIGLSLAPVAINMAaggPGA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 157 QQVAPVQNLCFVFIFVLGMFWANQRLTGLWKTTLIIWAVIIGTALYMLLFP-QYTGISYHQNFSPISSFFRHVSldfSLD 235
Cdd:COG2233  163 PDFGSPQNLLLALVTLAVILLLSVFGKGFLRRISILIGIVVGYIVALLLGMvDFSPVAEAPWFALPTPFPFGLP---TFD 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 236 PSVLISFLICFLALSINDLGSIQSIGEIIRPDNMEKRITRGVSFTGLGNILSGLFGVIGPVNFSLSPGVIASTGVASRFT 315
Cdd:COG2233  240 LGAILTMLPVALVTIAETIGDILAVGEITGRDITDPRLGRGLLGDGLATMLAGLFGGFPNTTYSENIGVIALTGVYSRYV 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 316 LIPTAFGLLLLSFLPSTIAFIGSIPSAVTGSVLIYIMCAQISSGLLVAFNTTGGfKFENGLIMGLPLMLSIIISFLpPNI 395
Cdd:COG2233  320 VAVAAVILILLGLFPKLGALIATIPSPVLGGATIVLFGMIAASGIRILVNVDFS-NPRNLLIVAVSLGLGLGVTGV-PGA 397
                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 503606329 396 ANSFPSSLRPIMGNGFVIGVLSVLILENVIYRRRNSE 432
Cdd:COG2233  398 LATLPATLGPLFLSGIALGALVAILLNLLLPGKKEEE 434
PRK11412 PRK11412
uracil/xanthine transporter;
18-425 1.79e-26

uracil/xanthine transporter;


Pssm-ID: 183124  Cd Length: 433  Bit Score: 110.64  E-value: 1.79e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  18 ELLLFGLQWLAIIVPIIIIIGKAIVGLHFSDPLDQVVYLQKLFFVSAVSLLAQVLWGHRLPLIIGPA-----AVLLVGIA 92
Cdd:PRK11412   9 ESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLLTLTQYAFLATALACFAQAFCGHRRAIMEGPGglwwgTILTITLG 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  93 ASQ-----GSSTSTIYSSILISGMILLLLSATGLFAKVKKLFTPQVIATILILIALTLTPM----IINLIFASQQVAPVQ 163
Cdd:PRK11412  89 EASrgtpiNDIATSLAVGIALSGVVTILIGFSGLGHRLARLFTPMVMVVFMLLLGAQLTTIffkgMLGLPFGIADPNGKI 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 164 NL------CFVFIFVLGMFWanqRLTGLWKTTLIIWAVIIGTALYMLLFPqytgiSYHQNFSPISSFFRHVSLDFSLDPS 237
Cdd:PRK11412 169 QLppfglsVAVMCLVLAMII---FLPQRIARYSLLVGTIVGWILWAFCFP-----SSHSLSGELHWQWFPLGSGGALEPG 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 238 VLISFLICFLALSINDLGSIQSIGEIIRPDNME-KRITRGVSFTGLGNILSGLFGVIGPVNFSLSPGVIASTGVASRFTL 316
Cdd:PRK11412 241 IILTAVITGLVNISNTYGAIRGTDVFYPQQGAGnTRYRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYRRRSF 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 317 IPTAFGLLLLSFLPSTIAFIGSIPSAVTGSVLIYIMCAQISSGLLVAFNTTggFKFENGLIMGLPLMLSIIISFLPPNIA 396
Cdd:PRK11412 321 IYGSVMCLLVALIPALTRLFCSIPLPVSSAVMLVSYLPLLGSALVFSQQIT--FTARNIYRLALPLFVGIFLMALPPVYL 398
                        410       420
                 ....*....|....*....|....*....
gi 503606329 397 NSFPSSLRPIMGNGFVIGVLSVLILENVI 425
Cdd:PRK11412 399 QDLPLTLRPLLSNGLLVGILLAVLMENLI 427
NCS2_1 NF037981
purine/pyrimidine permease; Proteins of this family usually have 14 transmembrane domains. ...
19-422 6.75e-25

purine/pyrimidine permease; Proteins of this family usually have 14 transmembrane domains. They belong to the NSC2 superfamily transporters. They are specific purine and/or pyrimidine permeases.


Pssm-ID: 468300  Cd Length: 419  Bit Score: 105.83  E-value: 6.75e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  19 LLLFGLQWLAIIVPIIIIIGKAIVGLHFSDPLDQVVYLQKLFFVSAVSLLAQVLWGHRLPLIIGPAAVL---------LV 89
Cdd:NF037981   3 LFLGGLQWMAFMIAASIAAPIAIADLFHLNPAETAGLVQRTIFVLGIAGLLQALFGHRLPINEGPAGLWwgvftiyagLV 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  90 GIA-ASQGSSTSTIYSSILISGMILLLLSATGLFAKVKKLFTPQVIATILILIALTLTPMIINLIF----ASQQVAPVQn 164
Cdd:NF037981  83 GTLySTNIETLQALQGAMLVSGVFFFLLSVTGLIDKLAVLFTPVVTFIYLLLLVLQLSGSFIKGMMgigyEGNEVDPLV- 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 165 LCFVFIFVLGMFWANQRLTGLWKTTLIIWAVIIGTALYMLLFPQYTGISYHQNFSPISSFFRHVSLDFslDPSVLI-SFL 243
Cdd:NF037981 162 FLLSLVVIILTFYFSRHKIKWIRQYSILLSLAGGWLLFALFGKAPAIAHTGGSIISLPELFVFGPPVF--DSGLIVtSFF 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 244 ICFLaLSINDLGSIQSIGEIIRPDNME---KRITRGVSFTGLGNILSGLFGVIGPVNFSLSPGVIASTGVASRFTLIPTA 320
Cdd:NF037981 240 ITLL-LIANMLASIRVMEEVLKKFGKIevsERYRQAGFASGINQLLGGLFSAIGSVPISGAAGFVATTGIPSLKPFIIGS 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329 321 FGLLLLSFLPSTIAFIGSIPSAVTGSVLIYIMCAQISsgllVAFNttgGFKFENG-----LIMGLPLMLSIIISFLPPNI 395
Cdd:NF037981 319 LLVVIISLFPPLMNIFASLPAPVGYAVTFVVFSKMVG----LAFG---ELDKEENkerarFVIGIALLAGVGAMFVPASA 391
                        410       420
                 ....*....|....*....|....*..
gi 503606329 396 ANSFPSSLRPIMGNGFVIGVLSVLILE 422
Cdd:NF037981 392 LSGLPPVVASLLNNGLILGTLIAIAVE 418
Xan_ur_permease pfam00860
Permease family; This family includes permeases for diverse substrates such as xanthine, ...
18-393 2.24e-24

Permease family; This family includes permeases for diverse substrates such as xanthine, uracil and vitamin C. However many members of this family are functionally uncharacterized and may transport other substrates. Members of this family have ten predicted transmembrane helices.


Pssm-ID: 395690 [Multi-domain]  Cd Length: 389  Bit Score: 103.92  E-value: 2.24e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329   18 ELLLFGLQWLAIIVPIIIIIGKaIVGLHFSDPLDQVVYLQKL-FFVSAVSLLAQVLW-GHRLPLIIGPA-----AVLLVG 90
Cdd:pfam00860   2 QLLLLGLQHLLAMFAATIVVPL-LVGDALGLGAEDLAQLISAtFLASGIGTLLQTLIfGIRLPIYLGSSfafvtALMIAL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329   91 IAASQGSSTSTIYSSILISGMILLLLSATGLFAKVKKLFTPQVIATILILIALTLTPMIIN------LIFASQQVAPVQN 164
Cdd:pfam00860  81 GLADWGIALAGLFGAVLVAGVLFTLISFTGLRGRLARLFPPVVTGPVVLLIGLSLAPIAVKgagggwAIADGLTVGLLDL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  165 LCFVFIFVLGMFWANQRLTGLWKTTLIIWAVIIGTALYMLLFpqytgisyHQNFSPISSFFRHVSLDF-------SLDPS 237
Cdd:pfam00860 161 LGLAVVVLAVILLLSVFLKGFFRQGPILIGIIAGWLLALFMG--------IVNFSPEVMDAPWFQLPHpfpfgtpLFNPG 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503606329  238 VLISFLICFLALSINDLGSIQSIGEII-RPDNMEKRITRGVSFTGLGNILSGLFGVIGPVNFSLSPGVIASTGVASRFTL 316
Cdd:pfam00860 233 LILTMLAVALVAIVESTGDIRAVAKVSgRDLKPKPDLRRGLLADGLATLLSGLFGAFPTTTYAENIGVVALTKVYSRRVG 312
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 503606329  317 IPTAFGLLLLSFLPSTIAFIGSIPSAVTGSVLIYIMCAQISSGlLVAFNTTGGFKFENGLIMGLPLMLSIIISFLPP 393
Cdd:pfam00860 313 VTAGVILILLGLIPKFAALFSSIPSPVLGGVMLVMFGMIAGSG-VSNLITVDLDSARNLLIIAVSLVLGLGISTVPE 388
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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