NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|503899382|ref|WP_014133376|]
View 

MULTISPECIES: GNAT family protein [Kitasatospora]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11447364)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  27367672|26818562|15581578|10940244
SCOP:  3000403

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 6-171 6.95e-38

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 128.19  E-value: 6.95e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382   6 TTPAVTLTPLDTDDAELLHGWLADPVAAHELGWWPRPLSALRERIERDIADGDDDAFL----VLRPDGEPVGLAELTGQS 81
Cdd:COG1670    4 ETERLRLRPLRPEDAEALAELLNDPEVARYLPGPPYSLEEARAWLERLLADWADGGALpfaiEDKEDGELIGVVGLYDID 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382  82 LADGTAGVRILTAPEHRGRGHGRAALDALTDLAFGELPFHRLAARPHTGNAPALALLERAGFTREGVERAACRHRGRHYD 161
Cdd:COG1670   84 RANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALVIDGRYRD 163

                        170
                 ....*....|
gi 503899382 162 LAVLSLLRPE 171
Cdd:COG1670  164 HVLYSLLREE 173
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 6-171 6.95e-38

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 128.19  E-value: 6.95e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382   6 TTPAVTLTPLDTDDAELLHGWLADPVAAHELGWWPRPLSALRERIERDIADGDDDAFL----VLRPDGEPVGLAELTGQS 81
Cdd:COG1670    4 ETERLRLRPLRPEDAEALAELLNDPEVARYLPGPPYSLEEARAWLERLLADWADGGALpfaiEDKEDGELIGVVGLYDID 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382  82 LADGTAGVRILTAPEHRGRGHGRAALDALTDLAFGELPFHRLAARPHTGNAPALALLERAGFTREGVERAACRHRGRHYD 161
Cdd:COG1670   84 RANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALVIDGRYRD 163

                        170
                 ....*....|
gi 503899382 162 LAVLSLLRPE 171
Cdd:COG1670  164 HVLYSLLREE 173
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 10-144 7.73e-20

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 80.85  E-value: 7.73e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382   10 VTLTPLDTDDAELLHGWLADPVAAHELGWWPRPLSALRERIERDIADGDDD---AFLVLRPDGEPVGLAELTGQSLADGT 86
Cdd:pfam13302   2 LLLRPLTEEDAEALFELLSDPEVMRYGVPWPLTLEEAREWLARIWAADEAErgyGWAIELKDTGFIGSIGLYDIDGEPER 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 503899382   87 AGVRILTAPEHRGRGHGRAALDALTDLAFGELPFHRLAARPHTGNAPALALLERAGFT 144
Cdd:pfam13302  82 AELGYWLGPDYWGKGYATEAVRALLEYAFEELGLPRLVARIDPENTASRRVLEKLGFK 139
PRK15130 PRK15130
spermidine N1-acetyltransferase; Provisional
 10-147 4.91e-06

spermidine N1-acetyltransferase; Provisional


Pssm-ID: 237916  Cd Length: 186  Bit Score: 44.79  E-value: 4.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382  10 VTLTPLDTDDAELLHGwlADPVAAHELGWWPRPLSA---LRERIERDIADGDDDAFlVLRPDGEPVGLAELTGQSLADGT 86
Cdd:PRK15130   7 VKLRPLEREDLRFVHQ--LDNNASVMRYWFEEPYEAfveLSDLYDKHIHDQSERRF-VVECDGEKAGLVELVEINHVHRR 83

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 503899382  87 AGVRILTAPEHRGRGHGRAALDALTDLAFGELPFHRLAARPHTGNAPALALLERAGFTREG 147
Cdd:PRK15130  84 AEFQIIISPEYQGKGLATRAAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFEVEG 144
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 62-115 5.72e-06

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 42.26  E-value: 5.72e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 503899382  62 FLVLRPDGEPVGLAELTGQSLADGTAGV-RILTAPEHRGRGHGRAALDALTDLAF 115
Cdd:cd04301    1 FLVAEDDGEIVGFASLSPDGSGGDTAYIgDLAVLPEYRGKGIGSALLEAAEEEAR 55
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 6-171 6.95e-38

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 128.19  E-value: 6.95e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382   6 TTPAVTLTPLDTDDAELLHGWLADPVAAHELGWWPRPLSALRERIERDIADGDDDAFL----VLRPDGEPVGLAELTGQS 81
Cdd:COG1670    4 ETERLRLRPLRPEDAEALAELLNDPEVARYLPGPPYSLEEARAWLERLLADWADGGALpfaiEDKEDGELIGVVGLYDID 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382  82 LADGTAGVRILTAPEHRGRGHGRAALDALTDLAFGELPFHRLAARPHTGNAPALALLERAGFTREGVERAACRHRGRHYD 161
Cdd:COG1670   84 RANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALVIDGRYRD 163

                        170
                 ....*....|
gi 503899382 162 LAVLSLLRPE 171
Cdd:COG1670  164 HVLYSLLREE 173
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 10-144 7.73e-20

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 80.85  E-value: 7.73e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382   10 VTLTPLDTDDAELLHGWLADPVAAHELGWWPRPLSALRERIERDIADGDDD---AFLVLRPDGEPVGLAELTGQSLADGT 86
Cdd:pfam13302   2 LLLRPLTEEDAEALFELLSDPEVMRYGVPWPLTLEEAREWLARIWAADEAErgyGWAIELKDTGFIGSIGLYDIDGEPER 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 503899382   87 AGVRILTAPEHRGRGHGRAALDALTDLAFGELPFHRLAARPHTGNAPALALLERAGFT 144
Cdd:pfam13302  82 AELGYWLGPDYWGKGYATEAVRALLEYAFEELGLPRLVARIDPENTASRRVLEKLGFK 139
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
9-168 7.71e-17

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 73.49  E-value: 7.71e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382   9 AVTLTPLDTDDAELLHGWLADPVAAHELGWW--PRPLSALRERIERDIADGDddAFLVLRPDGEPVGLAELTGQSLADGT 86
Cdd:COG1247    1 EMTIRPATPEDAPAIAAIYNEAIAEGTATFEtePPSEEEREAWFAAILAPGR--PVLVAEEDGEVVGFASLGPFRPRPAY 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382  87 AGV---RILTAPEHRGRGHGRAALDALTDLAfGELPFHRLAARPHTGNAPALALLERAGFTREGVERAACRHRGRHYDLA 163
Cdd:COG1247   79 RGTaeeSIYVDPDARGRGIGRALLEALIERA-RARGYRRLVAVVLADNEASIALYEKLGFEEVGTLPEVGFKFGRWLDLV 157


                 ....*
gi 503899382 164 VLSLL 168
Cdd:COG1247  158 LMQKR 162
Acetyltransf_8 pfam13523
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 18-147 2.06e-15

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 433280  Cd Length: 145  Bit Score: 69.47  E-value: 2.06e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382   18 DDAELLHGWLADPVAAHelgWWPRPLS-ALRERIERDIADGDD-DAFLVLRpDGEPVGLAEL---------TGQSLADGT 86
Cdd:pfam13523   4 ADLELLHRWMNDPRVAF---WWMLAGPlEQVREYLARLAADPHsHPYIGLL-DGEPFGYFEIywakedrlgEYYDARPGD 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 503899382   87 AGVRILTAP-EHRGRGHGRAALDALTDLAFGELPFHRLAARPHTGNAPALALLERAGFTREG 147
Cdd:pfam13523  80 RGIHLLIGEpAFRGRGFTTALLRALVHYLFADPRTRRVVVEPDVRNERAIRLLERAGFRKVK 141
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 29-143 2.46e-12

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 60.61  E-value: 2.46e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382   29 DPVAAHELGWWPRPLSALRERIERDIADGDDDAFLVLRPDGEPVGLAELTGQSLADGTAGV-RILTAPEHRGRGHGRAAL 107
Cdd:pfam00583   2 EALYELLSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLSIIDDEPPVGEIeGLAVAPEYRGKGIGTALL 81

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 503899382  108 DALTDLAFgELPFHRLAARPHTGNAPALALLERAGF 143
Cdd:pfam00583  82 QALLEWAR-ERGCERIFLEVAADNLAAIALYEKLGF 116
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 45-145 8.63e-09

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 51.59  E-value: 8.63e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382  45 ALRERIERDIADGDDDAFLVLRPDGEPVGLAELTgqSLADGTAGV-RILTAPEHRGRGHGRAALDALTDLAfGELPFHRL 123
Cdd:COG0454   19 ALDAELKAMEGSLAGAEFIAVDDKGEPIGFAGLR--RLDDKVLELkRLYVLPEYRGKGIGKALLEALLEWA-RERGCTAL 95

                         90       100
                 ....*....|....*....|..
gi 503899382 124 AARPHTGNAPALALLERAGFTR 145
Cdd:COG0454   96 ELDTLDGNPAAIRFYERLGFKE 117
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 58-145 1.86e-08

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 49.38  E-value: 1.86e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382   58 DDDAFLVLRPDGEPVGLAELTGQSLADGTAGVRILTAPEHRGRGHGRAALDALtDLAFGELPFHRLAARPHTgnaPALAL 137
Cdd:pfam13508   1 PGGRFFVAEDDGKIVGFAALLPLDDEGALAELRLAVHPEYRGQGIGRALLEAA-EAAAKEGGIKLLELETTN---RAAAF 76


                  ....*...
gi 503899382  138 LERAGFTR 145
Cdd:pfam13508  77 YEKLGFEE 84
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 45-145 6.08e-07

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 46.52  E-value: 6.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382  45 ALRERIERDIADGDDDAFLVLRPDGEPVGLAELTgqSLADGTAGVR-ILTAPEHRGRGHGRAALDALTDLAfGELPFHRL 123
Cdd:COG1246   13 AILELIRPYALEEEIGEFWVAEEDGEIVGCAALH--PLDEDLAELRsLAVHPDYRGRGIGRRLLEALLAEA-RELGLKRL 89

                         90       100
                 ....*....|....*....|..
gi 503899382 124 AArpHTgNAPALALLERAGFTR 145
Cdd:COG1246   90 FL--LT-TSAAIHFYEKLGFEE 108
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
51-147 6.18e-07

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 46.33  E-value: 6.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382  51 ERDIADGDDDAF-LVLRPDGEPVGLAELTGQSLADGTAGvRILTAPEHRGRGHGRAALDALTDLAFgELPFHR--LAARP 127
Cdd:COG2153   24 YLELDGKDEDARhLLAYDDGELVATARLLPPGDGEAKIG-RVAVLPEYRGQGLGRALMEAAIEEAR-ERGARRivLSAQA 101

                         90       100
                 ....*....|....*....|
gi 503899382 128 HtgnapALALLERAGFTREG 147
Cdd:COG2153  102 H-----AVGFYEKLGFVPVG 116
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 90-150 6.73e-07

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 45.42  E-value: 6.73e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 503899382  90 RILTAPEHRGRGHGRAALDALTDLAFgELPFHRLAARPHTGNAPALALLERAGFTREGVER 150
Cdd:COG0456   18 DLAVDPEYRGRGIGRALLEAALERAR-ERGARRLRLEVREDNEAAIALYEKLGFEEVGERP 77
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
70-147 2.02e-06

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 44.13  E-value: 2.02e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 503899382  70 EPVGLAELTGQSlaDGTAGV-RILTAPEHRGRGHGRAALDALTDLAFGELpFHRLAARPHTGNAPALALLERAGFTREG 147
Cdd:COG3393    1 ELVAMAGVRAES--PGVAEIsGVYTHPEYRGRGLASALVAALAREALARG-ARTPFLYVDADNPAARRLYERLGFRPVG 76
PRK15130 PRK15130
spermidine N1-acetyltransferase; Provisional
 10-147 4.91e-06

spermidine N1-acetyltransferase; Provisional


Pssm-ID: 237916  Cd Length: 186  Bit Score: 44.79  E-value: 4.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382  10 VTLTPLDTDDAELLHGwlADPVAAHELGWWPRPLSA---LRERIERDIADGDDDAFlVLRPDGEPVGLAELTGQSLADGT 86
Cdd:PRK15130   7 VKLRPLEREDLRFVHQ--LDNNASVMRYWFEEPYEAfveLSDLYDKHIHDQSERRF-VVECDGEKAGLVELVEINHVHRR 83

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 503899382  87 AGVRILTAPEHRGRGHGRAALDALTDLAFGELPFHRLAARPHTGNAPALALLERAGFTREG 147
Cdd:PRK15130  84 AEFQIIISPEYQGKGLATRAAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFEVEG 144
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 62-115 5.72e-06

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 42.26  E-value: 5.72e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 503899382  62 FLVLRPDGEPVGLAELTGQSLADGTAGV-RILTAPEHRGRGHGRAALDALTDLAF 115
Cdd:cd04301    1 FLVAEDDGEIVGFASLSPDGSGGDTAYIgDLAVLPEYRGKGIGSALLEAAEEEAR 55
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
14-147 5.80e-05

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 41.22  E-value: 5.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503899382  14 PLDTDDAELLHGWLAdpvAAHELGWWPRPLSALRErierdiaDGDDDAFLVLRPDGEPVGLAELTGQSLADGTAGV---R 90
Cdd:COG3153    3 PATPEDAEAIAALLR---AAFGPGREAELVDRLRE-------DPAAGLSLVAEDDGEIVGHVALSPVDIDGEGPALllgP 72

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 503899382  91 ILTAPEHRGRGHGRAALDALTDLAfGELPFHRLAArphTGNAPALALLERAGFTREG 147
Cdd:COG3153   73 LAVDPEYRGQGIGRALMRAALEAA-RERGARAVVL---LGDPSLLPFYERFGFRPAG 125
Acetyltransf_4 pfam13420
Acetyltransferase (GNAT) domain;
100-161 1.40e-04

Acetyltransferase (GNAT) domain;


Pssm-ID: 433192 [Multi-domain]  Cd Length: 153  Bit Score: 40.43  E-value: 1.40e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 503899382  100 RGHGRAALDALTDLAFGELPFHRLAARPHTGNAPALALLERAGFTREGVERAACRHRGRHYD 161
Cdd:pfam13420  89 EGINRELINAIIQYARKNQNIENLEACIASNNINAIVFLKAIGFEWLGIERNAIKKNGRWID 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH