|
Name |
Accession |
Description |
Interval |
E-value |
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
1-1399 |
0e+00 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 2736.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1 MKRNFKRNLSIIILVFALALYHVLPTCLYYSRPLNRKIDGREARKIIERFTRQVSDARNDLTLRVAKILSTLKLRGDIKQ 80
Cdd:PRK12911 1 MKQNFKRNLSIIICVFALALYYVLPTCLYYSRPLNKKIDGREARKIIERFTKQVSDARNDLIPRVSKILSTLKLRGHIKQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 81 HPSIPGVVNVHFPLAEDAALFIDNVVHGEPSVPVKSARLYVVGSSEFTGETVVQISGSLVTSLTEEDLSFVSYEDKDVTV 160
Cdd:PRK12911 81 HPSIPGVVNVHFKLAEDAALFIDNVVHGEPSVPIKSARLYVVGYSEFTGETVVQVSGSLVTSLTEKDFSFVSYEDEDETV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 161 SQELENLATNLFIESERPCECGYYSLWDSMPIEKVIHVTRNICSGLRLLPTRKTQVFLSRCLGTERDFTAFLARLEKALQ 240
Cdd:PRK12911 161 SQELENLATNLFIESERPCSCGYPSIWDTAPIEKVIQVARNLCSGLRLLPSRKTQAFLSRFFSSERDFTAFLSRLESLSQ 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 241 HEEVKEAREELKDASY-LLHSRNLRWNSISPKVVGNVVDCSELSPCFSSMSLTA-DGKLLFHFDAEVAANRQQLVGNERL 318
Cdd:PRK12911 241 DEEVKEARQELLDAVYeLLHSRACRWNSISPKIVGNVLDCSELSPFFSSMELTAkERKLLFHLDADVLAKRQQLSGEQRL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 319 DLERLFAMEKQHIATRLNRSVEETEFGFAVRLRDEAASGKIVLQGHRVCQRIVEHLTALVLNRPLAETCDLSTENFPVYG 398
Cdd:PRK12911 321 DFDSLLAVEKQHLATRLNRSVEETEFGFAFRLRDKDASGKIVLQGHRVCQGIVEHLTALVLNRPAAESCDLITENFPVYC 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 399 RELLDSDALGCFIFSPERSCRHFSKGSVYIVFKGLRSIVAKYEHAGAEEAALLQHDLQNLYACFIHTDAVSWSLGEDRVL 478
Cdd:PRK12911 401 REPRESDAFGCFIFSPERSCRHFSKGSVYIVLKGLRSIVAKYEQGGAEEAALFQKDLQNLYNCFIHTDAVSWSLGEDRVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 479 EIKEPLQRVIRIWGEEFVQSF-GKASLEVRDVRDRLAVVNRIEKTQHAELVRWDEQYRQAQCSMNPQVRLRAAIPHKNVF 557
Cdd:PRK12911 481 EIKEPLQRFIDVWGEEFVQSFeGKASLEVRDVRDRLATVNRIEKTRQAELVRWHEQYRQAQCSMDPQVRLRAAIPHKNLF 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 558 FENLKLNIRKYSRGEHVLRFGTDFVGGKQIRIAFRDHQGNLLTDKAGIDKVSDELYARLNKLGVSEVGMQREGDHIQVSV 637
Cdd:PRK12911 561 LENLKLNIRKYSRGEHVLRFGIDFVGGKQIRLAFKDHQGKQLTDKEGILKVSDELYARLNKLGVSEVEMRREGDHIHLSV 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 638 PGAAGISSADILGTSKMSFHVVNEQFSSRSPLRYEVQTFLDYLWFTARSLDECSPQAINRLAGALFHGDNGSAPANVRVA 717
Cdd:PRK12911 641 PGSAGISSAEILGTSKMSFHVVNEQFSSYSALRYEVQRFLDYLWFTARSQDKTSPEAINRLASALFNGDEGSAPASVREA 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 718 VEKLREAGLSFSK-ELEGGSASLDTQYSMIAIEKESREQVNPLMIVFRNHALEGASLKNIRPEFAVGEGYVLNFGVKDKA 796
Cdd:PRK12911 721 VTKLKEEGLAFSKsGLEGGSASLDTTYSMIAIEKDSEEKANPLMIVFRNYALDGASLKNIRPEFAVGEGYVLNFSVKDTA 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 797 TFSDGRE-TPVQQFHAWTSKFCQEGVSGTKNGLFSGGRGWRMAVVLDGYVISDPVLNVPLKDHASVSGNFSYREVHRLAT 875
Cdd:PRK12911 801 TFSDARElSPTESFHAWTSAYCQEGVSGTKNGQFSGGRGWRMAVVLDGYVVSDPVLNVPLKDHASVSGKFSHREVHRLAT 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 876 DLKSGAMSFIPEILSEEVVSPELGSSQRVQGILSVVLGLVVLIVLMSVYYRFGGVIASIAVLLNLLLIWASMQYLDAPLT 955
Cdd:PRK12911 881 DLKSGAMSFVPEVLSEEVISPELGKSQRTQGIISVCLGLAVLIVLMSVYYRFGGVIASGAVLLNLLLIWAALQYLDAPLT 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 956 LSGLAGIILAMGMAVDANVLVFERIREEYLLTRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLI 1035
Cdd:PRK12911 961 LSGLAGIVLAMGMAVDANVLVFERIREEYLLSRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLI 1040
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1036 IGIFSSMFTALFMTKFFFVIWVQKTRETQLHMMNKFIGIKHNFLKECKRLWVVSGVVLVLGCVGLGFGAWDSVFGMDFKG 1115
Cdd:PRK12911 1041 IGIFSSMFTALFMTKFFFMIWMNKTQETQLHMMNKFIGIKHDFLKECKRLWVVSGSVLVLGCVALGFGAWNSVLGMDFKG 1120
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1116 GYALTLD-SDVCEYNPEQMCSVLRKRFQQIGLSSRDYRVRRADSSGKVKIYLSQNALDRVEQIEGAGSEQkgSDYHLARV 1194
Cdd:PRK12911 1121 GYALTLDpSDVCEYDVEQMRSKLRKKFQQIGLSSRDFRIRTFDSSEKIKIYFSQNALDRVEAIEGAGSEQ--SDHHLALV 1198
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1195 LQVLSDSGSSTTSMVFDASRGSWFKVSGQLSNKMRTQAVIALFGALGIILLYVSLRFEWRYAFSAICALMHDLLATCAVL 1274
Cdd:PRK12911 1199 LGVLSDTGSDTSSEVFDATQNFWFKVSGQLSNKMRTQAVIALFGALGIILLYVSLRFEWRYAFSAICALIHDLLATCAVL 1278
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1275 VALHFFLQRIQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRREKLFTPMPILINDALQKTLGRTVMTTATTLSVLVILL 1354
Cdd:PRK12911 1279 VALHFFLQKIQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRQEKLFTPMPILINDALQKTLGRTVMTTATTLSVLLILL 1358
|
1370 1380 1390 1400
....*....|....*....|....*....|....*....|....*
gi 505318680 1355 FVGGGSIFNFAFIMTVGILLGTLSSLYIAPPLLLFMVRKEEQNSL 1399
Cdd:PRK12911 1359 FVGGGSIFNFAFIMTIGILLGTLSSLYIAPPLLLFMVRKEERNSL 1403
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
575-1067 |
2.14e-86 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 288.94 E-value: 2.14e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 575 LRFGTDFVGGKQIRIAFrDHQGNLLTDKAGIDKVSDE--------LYARLNKLGVSEVGMQREG-DHIQVSVPGAAGISS 645
Cdd:COG0342 31 IKLGLDLQGGVHLLLEV-DTDAALDEDGDGIREVTEEaldqaieiLRNRVNELGVSEPVIQRQGdDRIVVELPGVQDPAE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 646 A-DILG-TSKMSFHVVNEQfssrsplryevqtfldylwftarsldecspqainrlagalfHGDNGSAPANVRVAVEKLRE 723
Cdd:COG0342 110 AkELLGkTAKLEFRLVDDS-----------------------------------------ADAQAAVPAGSELLPCRDGQ 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 724 AGLsfskeleggsasldtqysmiaiekesreqvnplmiVFRNHALEGASLKNIRPEFAVGEG-YVLNFGVKDKATfsdgr 802
Cdd:COG0342 149 PYL-----------------------------------LLGPVVLTGDDLTDASAGFDQQTGqPVVSFTLDSEGA----- 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 803 etpvQQFHAWTSKFCqegvsgtknglfsggrGWRMAVVLDGYVISDPVLNVPLKD-HASVSGNFSYREVHRLATDLKSGA 881
Cdd:COG0342 189 ----KKFADATRENV----------------GKPLAIVLDGEVISAPVIQEPITGgSAQITGSFTVEEAQDLALLLRAGA 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 882 MSFIPEILSEEVVSPELGSSQRVQGILSVVLGLVVLIVLMSVYYRFGGVIASIAVLLNLLLIWASMQYLDAPLTLSGLAG 961
Cdd:COG0342 249 LPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYRLPGLVANIALALNVVLLLGVLSLLGATLTLPGIAG 328
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 962 IILAMGMAVDANVLVFERIREEYLLTRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSS 1041
Cdd:COG0342 329 IILTIGMAVDANVLIFERIREELRAGRSLRAAIEAGFKRAFSTILDANVTTLIAAVVLFVLGTGPVKGFAVTLILGILIS 408
|
490 500
....*....|....*....|....*.
gi 505318680 1042 MFTALFMTKFFFVIWVQKTRETQLHM 1067
Cdd:COG0342 409 MFTAVPVTRPLLNLLLGRRRLKKLGI 434
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
578-1053 |
4.84e-73 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 249.51 E-value: 4.84e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 578 GTDFVGGKQIRIA--FRDHQGNLLTDKAGIDKVSDELY-------ARLNKLGVSEVGMQREG-DHIQVSVPGAAGISSA- 646
Cdd:TIGR01129 2 GLDLRGGARVLLEvdMSTAVVLKLSEAEVNAIRKDALEqvitilrNRVNALGVSEPVVQRQGkDRIVVELPGVTDTSRAk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 647 DILG-TSKMSFHVVNeqfssrsplryevqtfldylwftarsldecspqainrlagalfhgDNGSAPANvrvAVEKLREAG 725
Cdd:TIGR01129 82 DILGgTATLEFRLVD---------------------------------------------DESTSPDD---ALAGNVPAG 113
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 726 lsfsKELEggsASLDTQYSMIAIEKESreqvnplmivfrnhALEGASLKNIRPEFAVGEG-YVLNFGVKDkatfsDGRET 804
Cdd:TIGR01129 114 ----SELL---DSRSGDPKYYLLKKSP--------------VLTGDHITDATSSVDQRSGqPVVSFSLDS-----EGARI 167
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 805 pvqqFhawtSKFCQEGVsgtknglfsggrGWRMAVVLDGYVISDPVLNVPL-KDHASVSGNFSYREVHRLATDLKSGAMS 883
Cdd:TIGR01129 168 ----F----GDFTQANI------------GKRLAIVLDNKVVSAPTIQEAItGGSGQITGNFTAEEANDLALVLRSGALP 227
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 884 FIPEILSEEVVSPELGSSQRVQGILSVVLGLVVLIVLMSVYYRFGGVIASIAVLLNLLLIWASMQYLDAPLTLSGLAGII 963
Cdd:TIGR01129 228 APLQILEERTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLI 307
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 964 LAMGMAVDANVLVFERIREEYLLTRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMF 1043
Cdd:TIGR01129 308 LTIGMAVDANVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLF 387
|
490
....*....|
gi 505318680 1044 TALFMTKFFF 1053
Cdd:TIGR01129 388 TALVFTRLLL 397
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
1200-1393 |
6.13e-73 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 240.97 E-value: 6.13e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1200 DSGSSTTSMVFDASRGSWFKVSGQLSNKMRTQAVIALFGALGIILLYVSLRFEWRYAFSAICALMHDLLATCAVLVALHf 1279
Cdd:pfam02355 1 VVEALLKNVGPDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLFG- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1280 flqrIQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRREKLFTPMPILINDALQKTLGRTVMTTATTLSVLVILLFVGGG 1359
Cdd:pfam02355 80 ----IEVDLATVAALLTIIGYSVNDTVVVFDRVRENLRKKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGG 155
|
170 180 190
....*....|....*....|....*....|....
gi 505318680 1360 SIFNFAFIMTVGILLGTLSSLYIAPPLLLFMVRK 1393
Cdd:pfam02355 156 SLKDFSLALLVGVIVGTYSSIFIASPILLDLGER 189
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
921-1071 |
2.23e-09 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 62.49 E-value: 2.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 921 MSVYYRFGGVIASIAVLLNLLLIWASMQYLDAPLTLSGLAGIILAMGMAVDANVLVFERIREE-YLLTRSLSESVEAGYK 999
Cdd:NF037998 462 LLFAYRLLGLFAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHlYKNKRSIEESFKIANK 541
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505318680 1000 KAFSAIFDSNLTTILASALLLMLDTGPIKGFAltlIIGIFSSMFTALFMTKFF-FVIWVQktreTQLHMMNKF 1071
Cdd:NF037998 542 ETIGIIVDALVVLLIPNLSLFWIGSNSIKSFA---TILLVGVIISLVLVIIVArLMIWLT----IKLQWFKKY 607
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
1199-1383 |
5.49e-04 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 44.77 E-value: 5.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1199 SDSGSSTTSMVFDAS-RGSWFKVSG------QLSNKMRTQAVIALfGALGIILLYVSLRFewrYAFSAICALMHDLLATC 1271
Cdd:NF037998 407 TETIARTIEALINQTtSGFTFKVNGisefnpVVTLLMLIASIIFL-LILAIAIMIYLLFA---YRLLGLFAIIIALTSIS 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1272 AVLVALHFFlqRIQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRREK---LFTPMPIlindALQKTLGRTVMTTATTLS 1348
Cdd:NF037998 483 LTLYSPTWF--GLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLYKNkrsIEESFKI----ANKETIGIIVDALVVLLI 556
|
170 180 190
....*....|....*....|....*....|....*
gi 505318680 1349 VLVILLFVGGGSIFNFAFIMTVGILLGTLSSLYIA 1383
Cdd:NF037998 557 PNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVA 591
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
930-1049 |
3.24e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 41.93 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 930 VIASIAVLLNLLLIWASMQYLDAPLTLSGLAGIILAMGMAVDANVLVFERIreeyllTRSLSES---VEAGYKKA----F 1002
Cdd:NF033617 358 LIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVVENI------HRHIEEGespLEAALKGAreigF 431
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 505318680 1003 SAIfdsNLTTILASALLLMLDTGPIKG-----FALTLIIGIFSSMFTALFMT 1049
Cdd:NF033617 432 TVI---AMTLTLVAVYLPILFMGGLTGrlfreFAVTLAGAVIISGIVALTLT 480
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
1017-1061 |
6.42e-03 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 41.30 E-value: 6.42e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 505318680 1017 ALLLMLDTGPIKGFALTLIIGIFSSMFTALFMTkFFFVIWVQKTR 1061
Cdd:NF037998 1166 AIILAATLPSIVGFGITLLIGVVVAMFVTLFLA-VPLWVWLEKRR 1209
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
1-1399 |
0e+00 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 2736.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1 MKRNFKRNLSIIILVFALALYHVLPTCLYYSRPLNRKIDGREARKIIERFTRQVSDARNDLTLRVAKILSTLKLRGDIKQ 80
Cdd:PRK12911 1 MKQNFKRNLSIIICVFALALYYVLPTCLYYSRPLNKKIDGREARKIIERFTKQVSDARNDLIPRVSKILSTLKLRGHIKQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 81 HPSIPGVVNVHFPLAEDAALFIDNVVHGEPSVPVKSARLYVVGSSEFTGETVVQISGSLVTSLTEEDLSFVSYEDKDVTV 160
Cdd:PRK12911 81 HPSIPGVVNVHFKLAEDAALFIDNVVHGEPSVPIKSARLYVVGYSEFTGETVVQVSGSLVTSLTEKDFSFVSYEDEDETV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 161 SQELENLATNLFIESERPCECGYYSLWDSMPIEKVIHVTRNICSGLRLLPTRKTQVFLSRCLGTERDFTAFLARLEKALQ 240
Cdd:PRK12911 161 SQELENLATNLFIESERPCSCGYPSIWDTAPIEKVIQVARNLCSGLRLLPSRKTQAFLSRFFSSERDFTAFLSRLESLSQ 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 241 HEEVKEAREELKDASY-LLHSRNLRWNSISPKVVGNVVDCSELSPCFSSMSLTA-DGKLLFHFDAEVAANRQQLVGNERL 318
Cdd:PRK12911 241 DEEVKEARQELLDAVYeLLHSRACRWNSISPKIVGNVLDCSELSPFFSSMELTAkERKLLFHLDADVLAKRQQLSGEQRL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 319 DLERLFAMEKQHIATRLNRSVEETEFGFAVRLRDEAASGKIVLQGHRVCQRIVEHLTALVLNRPLAETCDLSTENFPVYG 398
Cdd:PRK12911 321 DFDSLLAVEKQHLATRLNRSVEETEFGFAFRLRDKDASGKIVLQGHRVCQGIVEHLTALVLNRPAAESCDLITENFPVYC 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 399 RELLDSDALGCFIFSPERSCRHFSKGSVYIVFKGLRSIVAKYEHAGAEEAALLQHDLQNLYACFIHTDAVSWSLGEDRVL 478
Cdd:PRK12911 401 REPRESDAFGCFIFSPERSCRHFSKGSVYIVLKGLRSIVAKYEQGGAEEAALFQKDLQNLYNCFIHTDAVSWSLGEDRVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 479 EIKEPLQRVIRIWGEEFVQSF-GKASLEVRDVRDRLAVVNRIEKTQHAELVRWDEQYRQAQCSMNPQVRLRAAIPHKNVF 557
Cdd:PRK12911 481 EIKEPLQRFIDVWGEEFVQSFeGKASLEVRDVRDRLATVNRIEKTRQAELVRWHEQYRQAQCSMDPQVRLRAAIPHKNLF 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 558 FENLKLNIRKYSRGEHVLRFGTDFVGGKQIRIAFRDHQGNLLTDKAGIDKVSDELYARLNKLGVSEVGMQREGDHIQVSV 637
Cdd:PRK12911 561 LENLKLNIRKYSRGEHVLRFGIDFVGGKQIRLAFKDHQGKQLTDKEGILKVSDELYARLNKLGVSEVEMRREGDHIHLSV 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 638 PGAAGISSADILGTSKMSFHVVNEQFSSRSPLRYEVQTFLDYLWFTARSLDECSPQAINRLAGALFHGDNGSAPANVRVA 717
Cdd:PRK12911 641 PGSAGISSAEILGTSKMSFHVVNEQFSSYSALRYEVQRFLDYLWFTARSQDKTSPEAINRLASALFNGDEGSAPASVREA 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 718 VEKLREAGLSFSK-ELEGGSASLDTQYSMIAIEKESREQVNPLMIVFRNHALEGASLKNIRPEFAVGEGYVLNFGVKDKA 796
Cdd:PRK12911 721 VTKLKEEGLAFSKsGLEGGSASLDTTYSMIAIEKDSEEKANPLMIVFRNYALDGASLKNIRPEFAVGEGYVLNFSVKDTA 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 797 TFSDGRE-TPVQQFHAWTSKFCQEGVSGTKNGLFSGGRGWRMAVVLDGYVISDPVLNVPLKDHASVSGNFSYREVHRLAT 875
Cdd:PRK12911 801 TFSDARElSPTESFHAWTSAYCQEGVSGTKNGQFSGGRGWRMAVVLDGYVVSDPVLNVPLKDHASVSGKFSHREVHRLAT 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 876 DLKSGAMSFIPEILSEEVVSPELGSSQRVQGILSVVLGLVVLIVLMSVYYRFGGVIASIAVLLNLLLIWASMQYLDAPLT 955
Cdd:PRK12911 881 DLKSGAMSFVPEVLSEEVISPELGKSQRTQGIISVCLGLAVLIVLMSVYYRFGGVIASGAVLLNLLLIWAALQYLDAPLT 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 956 LSGLAGIILAMGMAVDANVLVFERIREEYLLTRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLI 1035
Cdd:PRK12911 961 LSGLAGIVLAMGMAVDANVLVFERIREEYLLSRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLI 1040
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1036 IGIFSSMFTALFMTKFFFVIWVQKTRETQLHMMNKFIGIKHNFLKECKRLWVVSGVVLVLGCVGLGFGAWDSVFGMDFKG 1115
Cdd:PRK12911 1041 IGIFSSMFTALFMTKFFFMIWMNKTQETQLHMMNKFIGIKHDFLKECKRLWVVSGSVLVLGCVALGFGAWNSVLGMDFKG 1120
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1116 GYALTLD-SDVCEYNPEQMCSVLRKRFQQIGLSSRDYRVRRADSSGKVKIYLSQNALDRVEQIEGAGSEQkgSDYHLARV 1194
Cdd:PRK12911 1121 GYALTLDpSDVCEYDVEQMRSKLRKKFQQIGLSSRDFRIRTFDSSEKIKIYFSQNALDRVEAIEGAGSEQ--SDHHLALV 1198
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1195 LQVLSDSGSSTTSMVFDASRGSWFKVSGQLSNKMRTQAVIALFGALGIILLYVSLRFEWRYAFSAICALMHDLLATCAVL 1274
Cdd:PRK12911 1199 LGVLSDTGSDTSSEVFDATQNFWFKVSGQLSNKMRTQAVIALFGALGIILLYVSLRFEWRYAFSAICALIHDLLATCAVL 1278
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1275 VALHFFLQRIQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRREKLFTPMPILINDALQKTLGRTVMTTATTLSVLVILL 1354
Cdd:PRK12911 1279 VALHFFLQKIQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRQEKLFTPMPILINDALQKTLGRTVMTTATTLSVLLILL 1358
|
1370 1380 1390 1400
....*....|....*....|....*....|....*....|....*
gi 505318680 1355 FVGGGSIFNFAFIMTVGILLGTLSSLYIAPPLLLFMVRKEEQNSL 1399
Cdd:PRK12911 1359 FVGGGSIFNFAFIMTIGILLGTLSSLYIAPPLLLFMVRKEERNSL 1403
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
575-1394 |
3.57e-138 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 441.98 E-value: 3.57e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 575 LRFGTDFVGGKQIRIAFRDHQGNLLTDKAGIDKVSDELYARLNKLGVSEVGMQREG-DHIQVSVPGAAGISSA-DILGTS 652
Cdd:PRK13024 31 INLGLDLQGGFEVLLEVSPADKGKKADREALDSTVEVLRNRIDGLGVSEPNIQREGnNRIRVELPGVQDPERArELLGST 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 653 -KMSFHVVNEQfssrsplryevqtfldylwftarsldecspQAINRLAGALFHGDNGSAPANVRVAVEklreaglsfSKE 731
Cdd:PRK13024 111 aKLTFRDVTDP------------------------------PPPGVGGPVVGPDEGKDTAVLNPVLLS---------GDD 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 732 LEGGSASLDTQysmiaieKESREQVNplmivfrnhalegaslknirpefavgegyvlnfgVKDKatfSDGREtpvqqfhA 811
Cdd:PRK13024 152 LTDAGAKFDQD-------QTNRPSVS----------------------------------LKLK---SEGAK-------K 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 812 WTsKFcqegvsgTKNGLFSGGRGWRMAVVLDGYVISDPVLNVPLK-DHASVSGNFSYREVHRLATDLKSGAMSFIPEILS 890
Cdd:PRK13024 181 WA-KV-------TEKNSKKGPPNNRIAIVLDPKVISAPTVNQPINgGSVQISGNFTVEEAKDLANLLNAGALPAPLKIIE 252
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 891 EEVVSPELGSSQRVQGILSVVLGLVVLIVLMSVYYRFGGVIASIAVLLNLLLIWASMQYLDAPLTLSGLAGIILAMGMAV 970
Cdd:PRK13024 253 SRSVGPTLGQDAIDAGIIAGIIGFALIFLFMLVYYGLPGLIANIALLLYIFLTLGALSSLGAVLTLPGIAGLVLGIGMAV 332
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 971 DANVLVFERIREEYLLTRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTALFMTK 1050
Cdd:PRK13024 333 DANVLIFERIKEELRKGKSLKKAFKKGFKNAFSTILDSNITTLIAAAILFFFGTGPVKGFATTLIIGILASLFTAVFLTR 412
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1051 FFFVIWVQK-------TRETQLHMMNKFIGIKH----NFLKEcKRLWVVSGVVLVLGCVGL----GFGawdsvFGMDFKG 1115
Cdd:PRK13024 413 LLLELLVKRgdkkpflFGVKKKKIHNINEGVTIfdriDFVKK-RKWFLIFSIVLVIAGIIIffifGLN-----LGIDFTG 486
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1116 GYALTLDSDVcEYNPEQmcsvLRKRFQQIGLSSRDyrvrradssgkVKIYLS--QNALDRVEQIEGAGSEQkgSDYHLAR 1193
Cdd:PRK13024 487 GTRYEIRTDQ-PVDLEQ----VRADLKELGLGEVN-----------IVTFGSdnNQVLVRTYGILSDDEEA--DTEIVAK 548
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1194 VLQVLSDSGSSTTSMVfdasrgswFKVSGQLSNKMRTQAVIALFGALGIILLYVSLRFEWRYAFSAICALMHDllatcaV 1273
Cdd:PRK13024 549 LKNALKNDKGGTIPSS--------ETVGPTVGKELARNAIIAVLIALIGILLYILIRFEWTFSLGAILALLHD------V 614
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1274 LVALHFF-LQRIQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRREKLFTPMPILINDALQKTLGRTVMTTATTLSVLVI 1352
Cdd:PRK13024 615 LIVIGFFsLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIRENLRLYKKKDLREIVNKSINQTLSRTINTSLTTLLVLLA 694
|
810 820 830 840
....*....|....*....|....*....|....*....|..
gi 505318680 1353 LLFVGGGSIFNFAFIMTVGILLGTLSSLYIAPPLLLFMVRKE 1394
Cdd:PRK13024 695 LLIFGGSSLRNFSLALLVGLIVGTYSSIFIAAPLWLDLEKRR 736
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
834-1395 |
1.73e-109 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 367.12 E-value: 1.73e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 834 GWRMAVVLDGYVISDPVLNVPLK-DHASVSGNFSYREVHRLATDLKSGAMSFIPEILSEEVVSPELGSSQRVQGILSVVL 912
Cdd:PRK14726 301 GKHFAIVLDGQVISAPVIDEAITgGEGRISGNFSEQGANDLAVLLRAGALPATLTVVEERTVGPGLGADSIAAGLVAGLI 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 913 GLVVLIVLMSVYYRFGGVIASIAVLLNLLLIWASMQYLDAPLTLSGLAGIILAMGMAVDANVLVFERIREEYLLTRSLSE 992
Cdd:PRK14726 381 AAILVAALMIGFYGFLGVIAVIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSNVLIYERIREEEKTGHSLIQ 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 993 SVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTALFMTKFFFVIWVQKTRETQL------- 1065
Cdd:PRK14726 461 ALDRGFSRALATIVDANVTILIAAVILFFLGSGAVRGFAVTLAVGILTTVFTAFTLTRSLVAVWLRRRRPKHLpkgvrtg 540
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1066 ---HMMNKFIGIkhnflkeckRLWVVSGVVLVLGCVGLGFGAWDSVFGMDFKGGYALTLDSDVCEYNPeqmcSVLRKRFQ 1142
Cdd:PRK14726 541 lfeGANIRFMGI---------RRYVFTLSAALSLASLVLFATVGLNLGIDFTGGSLIEVRAKQGNADI----ADIRARLN 607
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1143 QIGLSsrDYRVRRADSSGKVKIYL-SQNALDRVEQIEGAGSEQK-GSDYHLARVLQVlsdsGSSttsmvfdasrgswfkV 1220
Cdd:PRK14726 608 ELNLG--EVQVERFGSPRDALIRIaSQDGGENAEQSAVTLVRGElEDDYDFRRVEVV----GPA---------------V 666
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1221 SGQLSnkmrTQAVIALFGALGIILLYVSLRFEWRYAFSAICALMHDLLATCAVLValhffLQRIQIDLQAIGALMTVLGY 1300
Cdd:PRK14726 667 SGELT----MAATLGVLAALAAILIYIWIRFEWQFAVGAIIATLHDVILTLGLFV-----LTGIEFNLTSIAAILTIVGY 737
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1301 SLNNTLIIFDRIREDRREKLFTPMPILINDALQKTLGRTVMTTATTLSVLVILLFVGGGSIFNFAFIMTVGILLGTLSSL 1380
Cdd:PRK14726 738 SLNDTVVVYDRVRENLRRYKKMPLPILIDASINQTLSRTVLTSATTLLALLALYLFGGEVIRSFTFAMLFGVAVGTFSSI 817
|
570
....*....|....*
gi 505318680 1381 YIAPPLLLFMVRKEE 1395
Cdd:PRK14726 818 YIAAPVLIVFKLRPE 832
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
575-1067 |
2.14e-86 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 288.94 E-value: 2.14e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 575 LRFGTDFVGGKQIRIAFrDHQGNLLTDKAGIDKVSDE--------LYARLNKLGVSEVGMQREG-DHIQVSVPGAAGISS 645
Cdd:COG0342 31 IKLGLDLQGGVHLLLEV-DTDAALDEDGDGIREVTEEaldqaieiLRNRVNELGVSEPVIQRQGdDRIVVELPGVQDPAE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 646 A-DILG-TSKMSFHVVNEQfssrsplryevqtfldylwftarsldecspqainrlagalfHGDNGSAPANVRVAVEKLRE 723
Cdd:COG0342 110 AkELLGkTAKLEFRLVDDS-----------------------------------------ADAQAAVPAGSELLPCRDGQ 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 724 AGLsfskeleggsasldtqysmiaiekesreqvnplmiVFRNHALEGASLKNIRPEFAVGEG-YVLNFGVKDKATfsdgr 802
Cdd:COG0342 149 PYL-----------------------------------LLGPVVLTGDDLTDASAGFDQQTGqPVVSFTLDSEGA----- 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 803 etpvQQFHAWTSKFCqegvsgtknglfsggrGWRMAVVLDGYVISDPVLNVPLKD-HASVSGNFSYREVHRLATDLKSGA 881
Cdd:COG0342 189 ----KKFADATRENV----------------GKPLAIVLDGEVISAPVIQEPITGgSAQITGSFTVEEAQDLALLLRAGA 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 882 MSFIPEILSEEVVSPELGSSQRVQGILSVVLGLVVLIVLMSVYYRFGGVIASIAVLLNLLLIWASMQYLDAPLTLSGLAG 961
Cdd:COG0342 249 LPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYRLPGLVANIALALNVVLLLGVLSLLGATLTLPGIAG 328
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 962 IILAMGMAVDANVLVFERIREEYLLTRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSS 1041
Cdd:COG0342 329 IILTIGMAVDANVLIFERIREELRAGRSLRAAIEAGFKRAFSTILDANVTTLIAAVVLFVLGTGPVKGFAVTLILGILIS 408
|
490 500
....*....|....*....|....*.
gi 505318680 1042 MFTALFMTKFFFVIWVQKTRETQLHM 1067
Cdd:COG0342 409 MFTAVPVTRPLLNLLLGRRRLKKLGI 434
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
836-1061 |
1.76e-79 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 270.17 E-value: 1.76e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 836 RMAVVLDGYVISDPVLNVPLKDH-ASVSGNFSYREVHRLATDLKSGAMSFIPEILSEEVVSPELGSSQRVQGILSVVLGL 914
Cdd:PRK05812 228 RMAIVLDGEVISAPVIQSAITGGsAQITGNFTAEEARDLALLLRAGALPAPLEIVEERTIGPSLGADSIRAGLIAGLIGL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 915 VVLIVLMSVYYRFGGVIASIAVLLNLLLIWASMQYLDAPLTLSGLAGIILAMGMAVDANVLVFERIREEYLLTRSLSESV 994
Cdd:PRK05812 308 ALVLLFMILYYRLFGLIANIALVANLVLILAVLSLLGATLTLPGIAGIVLTIGMAVDANVLIFERIREELREGRSLRSAI 387
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505318680 995 EAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTALFMTKFFFVIWVQKTR 1061
Cdd:PRK05812 388 EAGFKRAFSTILDSNITTLIAAIILYALGTGPVKGFAVTLGIGILTSMFTAITVTRALVNLLYGRRK 454
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
578-1053 |
4.84e-73 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 249.51 E-value: 4.84e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 578 GTDFVGGKQIRIA--FRDHQGNLLTDKAGIDKVSDELY-------ARLNKLGVSEVGMQREG-DHIQVSVPGAAGISSA- 646
Cdd:TIGR01129 2 GLDLRGGARVLLEvdMSTAVVLKLSEAEVNAIRKDALEqvitilrNRVNALGVSEPVVQRQGkDRIVVELPGVTDTSRAk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 647 DILG-TSKMSFHVVNeqfssrsplryevqtfldylwftarsldecspqainrlagalfhgDNGSAPANvrvAVEKLREAG 725
Cdd:TIGR01129 82 DILGgTATLEFRLVD---------------------------------------------DESTSPDD---ALAGNVPAG 113
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 726 lsfsKELEggsASLDTQYSMIAIEKESreqvnplmivfrnhALEGASLKNIRPEFAVGEG-YVLNFGVKDkatfsDGRET 804
Cdd:TIGR01129 114 ----SELL---DSRSGDPKYYLLKKSP--------------VLTGDHITDATSSVDQRSGqPVVSFSLDS-----EGARI 167
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 805 pvqqFhawtSKFCQEGVsgtknglfsggrGWRMAVVLDGYVISDPVLNVPL-KDHASVSGNFSYREVHRLATDLKSGAMS 883
Cdd:TIGR01129 168 ----F----GDFTQANI------------GKRLAIVLDNKVVSAPTIQEAItGGSGQITGNFTAEEANDLALVLRSGALP 227
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 884 FIPEILSEEVVSPELGSSQRVQGILSVVLGLVVLIVLMSVYYRFGGVIASIAVLLNLLLIWASMQYLDAPLTLSGLAGII 963
Cdd:TIGR01129 228 APLQILEERTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLI 307
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 964 LAMGMAVDANVLVFERIREEYLLTRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMF 1043
Cdd:TIGR01129 308 LTIGMAVDANVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLF 387
|
490
....*....|
gi 505318680 1044 TALFMTKFFF 1053
Cdd:TIGR01129 388 TALVFTRLLL 397
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
1200-1393 |
6.13e-73 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 240.97 E-value: 6.13e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1200 DSGSSTTSMVFDASRGSWFKVSGQLSNKMRTQAVIALFGALGIILLYVSLRFEWRYAFSAICALMHDLLATCAVLVALHf 1279
Cdd:pfam02355 1 VVEALLKNVGPDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLFG- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1280 flqrIQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRREKLFTPMPILINDALQKTLGRTVMTTATTLSVLVILLFVGGG 1359
Cdd:pfam02355 80 ----IEVDLATVAALLTIIGYSVNDTVVVFDRVRENLRKKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGG 155
|
170 180 190
....*....|....*....|....*....|....
gi 505318680 1360 SIFNFAFIMTVGILLGTLSSLYIAPPLLLFMVRK 1393
Cdd:pfam02355 156 SLKDFSLALLVGVIVGTYSSIFIASPILLDLGER 189
|
|
| SecF |
COG0341 |
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ... |
1109-1393 |
8.99e-71 |
|
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440110 [Multi-domain] Cd Length: 291 Bit Score: 239.18 E-value: 8.99e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1109 FGMDFKGGYALTLDSDVcEYNPEQmcsvLRKRFQQIGLSsrDYRVRRADSSGKVKIylsqnaldRVEQIEGAGSEQKgsd 1188
Cdd:COG0341 40 LGIDFTGGTLIEVSFEQ-PVDLEE----VREALEEAGLG--DASVQTFGSDNDVLI--------RTPPLDGESAEEV--- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1189 yhlARVLQVLSDSGSSTTSMVFDasrgswfKVSGQLSNKMRTQAVIALFGALGIILLYVSLRFEWRYAFSAICALMHDLL 1268
Cdd:COG0341 102 ---EKVRAALKEAFGDVEIVRVE-------FVGPTVGKELTRKALLALLVALIGILIYIAFRFEWRFAVGAVVALLHDVL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1269 ATCAVLVALhfflqRIQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRREKLFTPMPILINDALQKTLGRTVMTTATTLS 1348
Cdd:COG0341 172 ITLGIFSLF-----GLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLAEIINLSINQTLSRTINTSLTTLL 246
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 505318680 1349 VLVILLFVGGGSIFNFAFIMTVGILLGTLSSLYIAPPLLLFMVRK 1393
Cdd:COG0341 247 VVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLLLWLGKR 291
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
828-1388 |
3.40e-63 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 231.05 E-value: 3.40e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 828 LFSGGRGWRMAVVLDGYVISDPVLNVPL-KDHASVSGNFSYREVHRLATDLKSGAMSFIPEILSEEVVSPELGSSQRVQG 906
Cdd:PRK13023 201 LTAQGNENSFAIVVDNQVVSAPTVSGPLdTSELQIEGAFDLQAANNMAVVLRSGALPQAVTVLEERTIASALGEDYASAA 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 907 ILSVVLGLVVLIVLMSVYYRFGGVIASIAVLLNLLLIWASMQYLDAPLTLSGLAGIILAMGMAVDANVLVFERIREEYLL 986
Cdd:PRK13023 281 VLAALLAALVVGLFMVLSYGILGVIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRRK 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 987 TRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTALFMTKFFFVIWVQ--KTRETQ 1064
Cdd:PRK13023 361 GYSVVQAMESGFYRALSTIVDANLTTLIAALVLFLLGSGTVHGFALTVAIGIGTTLFTTLTFTRLLIAQWVRtaKPKEVP 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1065 LHMMNKFIGIKH-NFLkeckRLWVVSGVVLVLGC-------VGLGFGawdsvFGMDFKGGYALTLDSDVCEYNPEQmcsv 1136
Cdd:PRK13023 441 KRRLKLVPTVTHiPFM----RLQFVTLGISVLACaivvalfVNIGFN-----YGIDFRGGSMVELQARNGDANLED---- 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1137 LRKRFQQIGLSSRDYRVRRADSSGKVkIYLSQNALDRVEQIEGAGSEQK-GSDYHLARVlQVLSDSgssttsmvfdasrg 1215
Cdd:PRK13023 508 INERLAELNIDSARVLPAKSPRSALV-IIGSQEVGDDAEQTVAVKLRGEfEQDYSFQRV-DVVGPT-------------- 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1216 swfkVSGQLSNKMRTQAVIALFGalgiILLYVSLRFEWRYAFSAICALMHDLlatcaVLVALHFFLQRIQIDLQAIGALM 1295
Cdd:PRK13023 572 ----VSEQLSRAGVLAVILSLIG----IFIYVWFRFRWQLALGAVLSTLHDV-----VILSGMFIVFRMEFNLWSVAAIL 638
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1296 TVLGYSLNNTLIIFDRIREDRREKLFTPMPILINDALQKTLGRTVMTTATTLSVLVILLFVGGGSIFNFAFIMTVGILLG 1375
Cdd:PRK13023 639 TIIGYSLNDTVVIYDRVRENLRRYKSAPLPAIIDASINQTLSRTLLTSFVTFLAHVPLYAFGGSEIRMFALALSVGIIVA 718
|
570
....*....|...
gi 505318680 1376 TLSSLYIAPPLLL 1388
Cdd:PRK13023 719 SYSSIFIAAPLLV 731
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
1109-1383 |
8.98e-49 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 174.00 E-value: 8.98e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1109 FGMDFKGGYALTLDSdvcEYNPEQmcSVLRKRFQQIGLssrdyrvrraDSSGKVKIYLSQNALDRVEQIEGAGSEQKGSD 1188
Cdd:TIGR00966 4 FGIDFTGGTVIETRL---EQAADV--AEVRDVLEKAGI----------EGVVIQEFGSSHTIMIRIPTLDTEQSEELREA 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1189 yhlarVLQVLSDSGSSTTSMVFDASRGSWfkvSGQLSNKmrtqAVIALFGALGIILLYVSLRFEWRYAFSAICALMHDLL 1268
Cdd:TIGR00966 69 -----LEEALKNVDPDAEIRSIDAVGPSV---GGELARK----AVLALLAALVLILIYITVRFEWRFALGAIVALVHDVI 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1269 ATCAVLVALHfflqrIQIDLQAIGALMTVLGYSLNNTLIIFDRIRED-RREKLFTPMPIlINDALQKTLGRTVMTTATTL 1347
Cdd:TIGR00966 137 ITVGVYSLFG-----IEVNLTTVAALLTIIGYSINDTVVVFDRIRENlRKYTRKTFTEV-INLSINQTLSRTINTSLTTL 210
|
250 260 270
....*....|....*....|....*....|....*.
gi 505318680 1348 SVLVILLFVGGGSIFNFAFIMTVGILLGTLSSLYIA 1383
Cdd:TIGR00966 211 LAVLALYVFGGGVIKDFSLALLVGVIVGTYSSIFIA 246
|
|
| secD |
PRK12933 |
protein translocase subunit SecD; |
845-1047 |
3.78e-40 |
|
protein translocase subunit SecD;
Pssm-ID: 183831 [Multi-domain] Cd Length: 604 Bit Score: 158.70 E-value: 3.78e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 845 VISDPVLNVPLKDHASVSGNFSYREVHRLATDLKSGAMSFIPEILSEEVVSPELGSSQRVQGILSVVLGLVVLIVLMSVY 924
Cdd:PRK12933 381 VISVATIQSQLGDRFRITGAGSYQEAQQLALLLRAGSLTAPVTIVEERTIGPSLGAENIENGFAALALGMGITLLFMALW 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 925 YRFGGVIASIAVLLNLLLIWASMQYL-DAPLTLSGLAGIILAMGMAVDANVLVFERIREEYLLTRSLSESVEAGYKKAFS 1003
Cdd:PRK12933 461 YRRLGWVANVALIANMVCLFGLLALIpGAVLTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKEGRSFAQAIDTGFDSAFS 540
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 505318680 1004 AIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTALF 1047
Cdd:PRK12933 541 TIFDANFTTMITAVVLYSIGNGPIQGFALTLGLGLLTSMFTGIF 584
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
887-1046 |
2.02e-38 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 142.40 E-value: 2.02e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 887 EILSEEVVS---PELGSSQRVQGILSVVLGLVVLIVLMSVYYRFGGVIASIAVLLN-LLLIWASMQYLDAPLTLSGLAGI 962
Cdd:TIGR00916 27 KVISAPVVGtvgPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHdVILILGVLSLFGATLTLPGIAGL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 963 ILAMGMAVDANVLVFERIREE--YLLTRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFS 1040
Cdd:TIGR00916 107 LTIIGYSVDDTVVIFDRIREElrKYKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIA 186
|
....*.
gi 505318680 1041 SMFTAL 1046
Cdd:TIGR00916 187 GTYSSI 192
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
1231-1380 |
7.84e-37 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 137.77 E-value: 7.84e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1231 QAVIALFGALGIILLYVSLRFEWRYAFSAICALMHDLLATCAVLVALHFflqriQIDLQAIGALMTVLGYSLNNTLIIFD 1310
Cdd:TIGR00916 48 AGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDVILILGVLSLFGA-----TLTLPGIAGLLTIIGYSVDDTVVIFD 122
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505318680 1311 RIRED-RREKLFTPMPIlINDALQKTLGRTVMTTATTLSVLVILLFVGGGSIFNFAFIMTVGILLGTLSSL 1380
Cdd:TIGR00916 123 RIREElRKYKGRTFREA-INLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
|
|
| secF |
PRK13021 |
preprotein translocase subunit SecF; Reviewed |
1109-1390 |
4.84e-32 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 237274 [Multi-domain] Cd Length: 297 Bit Score: 127.66 E-value: 4.84e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1109 FGMDFKGGYA--LTLDSDVceyNPEQMCSVLRKRFQQiglssrDYRVRRADSSGKVkiylsqnaldrveQIEGAGSEQKG 1186
Cdd:PRK13021 35 WGLDFTGGVVteVQLDRKI---TSSELQPLLNAAYQQ------EVSVISASEPGRW-------------VLRYAPADTAQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1187 SDYHLARVLQVLSDSGSSTTSMVfdasrgswfkVSGQLSNKMRTQAVIALFGALGIILLYVSLRFEWRYAFSAICALMHD 1266
Cdd:PRK13021 93 SNVDIQQALAPLGTEVQVLNSSI----------VGPQVGQELAEQGGLALLVAMLCILGYLSYRFEWRLASGALFALVHD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1267 LlatcaVLVALHFFLQRIQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRREKLFTPMPILINDALQKTLGRTVMTTATT 1346
Cdd:PRK13021 163 V-----IFVLAFFALTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPKLAIQEINNQAIVATFSRTMVTSGTT 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 505318680 1347 LSVLVILLFVGGGSIFNFAFIMTVGILLGTLSSLYIAPPLLLFM 1390
Cdd:PRK13021 238 LMTVGALWIMGGGPLEGFSIAMFIGILTGTFSSISVGTSLPELL 281
|
|
| secD |
PRK08343 |
preprotein translocase subunit SecD; Reviewed |
714-1039 |
2.63e-15 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 236245 [Multi-domain] Cd Length: 417 Bit Score: 79.92 E-value: 2.63e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 714 VRVAVEKLREAGLSfskeleGGSA-SLDTQYSMIAIEKESREQVNPLM---------IVF----RNHALEGASLKNIRP- 778
Cdd:PRK08343 69 VEILESRLNALGLK------DIKVyPVGDQYIVVEVPGVDADTAKEIIekqgvfearIQTpgnnNETVLTGDDIESVGSp 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 779 -EFAVGEGYVLNFGVKDKATfsdgretpvqqfhawtSKFcQEGVSGTknGLFSGGRGWRMAVVLDGYVISDPVLNVPL-- 855
Cdd:PRK08343 143 sQDPSGGAWGVPFTLSEDGA----------------EKF-AEVAKGK--GATDDPSGHPLDMYLDGELIYAAPLSPDLas 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 856 -KDHASV--------SGNFSYREVHRLATDLKSGAMSFIPEILSEEVVSPELGSSQRVQ----GILSVVLGLVVlivlms 922
Cdd:PRK08343 204 gLASGPVvitvgstgTTEEAKEEAKELYIHLRSGALPVKLDIEGSGSVSPSLGEQFKKGsliaGLLALLAVALV------ 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 923 VYYRFGG-------VIASIAVLLNLLLIWASMQYldaPLTLSGLAGIILAMGMAVDANVLVF-ERIREEYLLTRSLsesV 994
Cdd:PRK08343 278 VFLRYREprialpmVITSLSEVIIILGFAALIGW---QLDLASIAGIIAVIGTGVDDLIIITdEVLHEGKVPSRKV---F 351
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 505318680 995 EAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIF 1039
Cdd:PRK08343 352 LSRIKRAFFIIFAAAATTIAAMSPLAVMGLGDLKGFAITTILGVL 396
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
921-1398 |
3.51e-15 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 81.06 E-value: 3.51e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 921 MSVYYR-FGGVIASIAVLLnLLLIWA--SMQYLDAPLT-LSGLAGIILaMGMAVDANVLVFERIREEYLLTRSLSESVEA 996
Cdd:COG1033 235 LFLFFRsLRGVLLPLLVVL-LAVIWTlgLMGLLGIPLSpLTILVPPLL-LAIGIDYGIHLLNRYREERRKGLDKREALRE 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 997 GYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTALFMT---KFFFVIWVQKTRE-TQLHMMNKFI 1072
Cdd:COG1033 313 ALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVLLAFLTSLTLLpalLSLLPRPKPKTRRlKKPPELGRLL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1073 GikhNFLKECKRLWVVSGVVLVLGCVGLGFGAWDSVFGMD---------------------FKGGYALTL----DSDVCE 1127
Cdd:COG1033 393 A---KLARFVLRRPKVILVVALVLAVVSLYGISRLKVEYDfedylpedspirqdldfieenFGGSDPLEVvvdtGEPDGL 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1128 YNPEqmcsVLRK--RFQQIgLSSRDY------------RVRRADSSGKVKIY--------LSQNALDRVEQIEGAGSEQK 1185
Cdd:COG1033 470 KDPE----VLKEidRLQDY-LESLPEvgkvlsladlvkELNQALNEGDPKYYalpesrelLAQLLLLLSSPPGDDLSRFV 544
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1186 GSDYHLARVLQVLSDSGSSTTSMVFDASR----------GSWFKVSGQ------LSNKMRTQAVIALFGALGII--LLYV 1247
Cdd:COG1033 545 DEDYSAARVTVRLKDLDSEEIKALVEEVRaflaenfppdGVEVTLTGSavlfaaINESVIESQIRSLLLALLLIflLLLL 624
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1248 SLRfEWRYAFSAICALMhdllatCAVLValhfflqriqidlqaIGALMTVLGYSLN-NTLIIF---------------DR 1311
Cdd:COG1033 625 AFR-SLRLGLISLIPNL------LPILL---------------TFGLMGLLGIPLNiATAVVAsialgigvdytihflSR 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1312 IREDRREKLFTPMPILIndALQKTlGRTVMTTATTLSV-LVILLFVGGGSIFNFAFIMTVGILLGTLSSLYIAPPLLLFM 1390
Cdd:COG1033 683 YREERRKGGDLEEAIRR--ALRTT-GKAILFTSLTLAAgFGVLLFSSFPPLADFGLLLALGLLVALLAALLLLPALLLLL 759
|
....*...
gi 505318680 1391 VRKEEQNS 1398
Cdd:COG1033 760 DPRIAKKR 767
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
1176-1387 |
4.29e-11 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 66.54 E-value: 4.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1176 QIEGAGSEQKGSDyhLARVLQvlsdSGSSTTSMVFDASRgswfKVSGQLSNKMRTQAVIALFGALGIILLYVSLRFEWRY 1255
Cdd:TIGR01129 204 QITGNFTAEEAND--LALVLR----SGALPAPLQILEER----TIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRLFG 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1256 AFSAIcALMHDLLATCAVLVALHFFLqriqiDLQAIGALMTVLGYSLNNTLIIFDRIREDRREKlfTPMPILINDALQKT 1335
Cdd:TIGR01129 274 LIAAI-ALVINIVLILAILSAFGATL-----TLPGIAGLILTIGMAVDANVLIYERIKEELRLG--KSVRQAIEAGFERA 345
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 505318680 1336 LGRTVMTTATTLSVLVILLFVGGGSIFNFAFIMTVGILLGTLSSLYIAPPLL 1387
Cdd:TIGR01129 346 FSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLFTALVFTRLLL 397
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
923-1387 |
1.14e-10 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 66.40 E-value: 1.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 923 VYYRFGGVIASI----AVLLNLLLIWASMQYLDAPLTLSGLAGIILAMGMAVDANVLVFERIREEYLLTRSLSESVEAGY 998
Cdd:TIGR00921 210 LLLDFKRWWRPLlplvIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAV 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 999 KKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTALFMTK---FFFVIWVQKTRETQLHMMNKFIGIK 1075
Cdd:TIGR00921 290 RRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLVLPallQSIDIGREKVKKEIIAIGGKSSEIE 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1076 HNFLKECK----RLWVVSGVVLVLGCVGLgfgawdsvfgmdfKGGYALTLDSDVCEYNPEQMCSVLRKR----------- 1140
Cdd:TIGR00921 370 EELSKVLSitvrHPVPALVAALIITGLGL-------------YGAAGIKPEVNIEKFIPQDLPSLQARKvieshmggshd 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1141 FQQIGLSSRDYR----VRRAD--------SSGKVKIYLSQNALDRVEQIEGA----------------GSEQKGSDYHLA 1192
Cdd:TIGR00921 437 FATILVKADDVRdpelVRFMDelsrdikaTGVAARVFGAPSIIDLVKEVEGLpapersalepipedeeGGYISGGQIKVA 516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1193 RVLQVLSDSGSSTT-----SMV--FDASRGSWFKVSG----------QLSNKMRTQAVIALFGALgiILLYVSLRfEWRY 1255
Cdd:TIGR00921 517 VIQVQLKQGEPKVQgrkilRDVqhEHPPPGVKVGVTGlpvafaemheLVNEGMRRMTIAGAILVL--MILLAVFR-NPIK 593
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1256 AFSAICALMHDLLATCAVLvalhfFLQRIQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRREklFTPMpilinDALQKT 1335
Cdd:TIGR00921 594 AVFPLIAIGSGILWAIGLM-----GLRGIPSFLAMATTISIILGLGMDYSIHLAERYFEERKE--HGPK-----EAITHT 661
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 505318680 1336 LGRT----VMTTATTLSVLVILLFVGGGSIFNFAFIMTVGILLGTLSSLYIAPPLL 1387
Cdd:TIGR00921 662 MERTgpgiLFSGLTTAGGFLSLLLSHFPIMRNFGLVQGIGVLSSLTAALVVFPALL 717
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
886-1048 |
9.35e-10 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 59.54 E-value: 9.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 886 PEILSEEVVSPELGSSQRVQGILSVVLGLVVLIVLMSVYYRFGGVIASIAVLL-NLLLIWASMQYLDAPLTLSGLAGIIL 964
Cdd:pfam02355 13 AEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAhDVIITVGVFSLFGIEVDLATVAALLT 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 965 AMGMAVDANVLVFERIREEYLLTR--SLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSM 1042
Cdd:pfam02355 93 IIGYSVNDTVVVFDRVRENLRKKTraTLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLALLVGVIVGT 172
|
....*.
gi 505318680 1043 FTALFM 1048
Cdd:pfam02355 173 YSSIFI 178
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
921-1071 |
2.23e-09 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 62.49 E-value: 2.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 921 MSVYYRFGGVIASIAVLLNLLLIWASMQYLDAPLTLSGLAGIILAMGMAVDANVLVFERIREE-YLLTRSLSESVEAGYK 999
Cdd:NF037998 462 LLFAYRLLGLFAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHlYKNKRSIEESFKIANK 541
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505318680 1000 KAFSAIFDSNLTTILASALLLMLDTGPIKGFAltlIIGIFSSMFTALFMTKFF-FVIWVQktreTQLHMMNKF 1071
Cdd:NF037998 542 ETIGIIVDALVVLLIPNLSLFWIGSNSIKSFA---TILLVGVIISLVLVIIVArLMIWLT----IKLQWFKKY 607
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
880-1048 |
4.06e-07 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 52.66 E-value: 4.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 880 GAMSFIPEILSEEVVSPELGSSQRVQGILSVVLGLVVLIVLMSVYYRFGGVIASIAVLL-NLLLIWASMQYLDAPLTLSG 958
Cdd:TIGR00966 74 KNVDPDAEIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEWRFALGAIVALVhDVIITVGVYSLFGIEVNLTT 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 959 LAGIILAMGMAVDANVLVFERIREEYLL--TRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLII 1036
Cdd:TIGR00966 154 VAALLTIIGYSINDTVVVFDRIRENLRKytRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLV 233
|
170
....*....|..
gi 505318680 1037 GIFSSMFTALFM 1048
Cdd:TIGR00966 234 GVIVGTYSSIFI 245
|
|
| secF |
PRK13021 |
preprotein translocase subunit SecF; Reviewed |
887-1046 |
1.21e-06 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 237274 [Multi-domain] Cd Length: 297 Bit Score: 51.78 E-value: 1.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 887 EILSEEVVSPELGSSQRVQGILSVVLGLVVLIVLMSvyYRFGGVIAS---IAVLLNLLLIWASMQYLDAPLTLSGLAGII 963
Cdd:PRK13021 109 QVLNSSIVGPQVGQELAEQGGLALLVAMLCILGYLS--YRFEWRLASgalFALVHDVIFVLAFFALTQMEFNLTVLAAVL 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 964 LAMGMAVDANVLVFERIREEYLLTRSLS--ESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSS 1041
Cdd:PRK13021 187 AILGYSLNDSIIIADRIRELLIAKPKLAiqEINNQAIVATFSRTMVTSGTTLMTVGALWIMGGGPLEGFSIAMFIGILTG 266
|
....*
gi 505318680 1042 MFTAL 1046
Cdd:PRK13021 267 TFSSI 271
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
927-1046 |
2.58e-06 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 52.08 E-value: 2.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 927 FGGVIASIAVLLN--------LLLIWASMQYLDAPLTLSGLAgIILAMGMAVDANVLVFERIREEYLLTRSLSESVEAGY 998
Cdd:COG2409 190 FRSLVAALLPLLTaglavgvaLGLLALLAAFTDVSSFAPNLL-TMLGLGVGIDYALFLVSRYREELRAGEDREEAVARAV 268
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 505318680 999 KKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTAL 1046
Cdd:COG2409 269 ATAGRAVLFSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVAVLAAL 316
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
1176-1399 |
2.82e-06 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 51.65 E-value: 2.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1176 QIEGAGSEQKGSDyhLARVLQvlsdSGSSTTSMVFDASRgswfKVSGQLSNKMRTQAVIALFGALGIILLYVSLRfewrY 1255
Cdd:COG0342 227 QITGSFTVEEAQD--LALLLR----AGALPAPLEIVEER----TVGPTLGADSIEKGLIAGLIGLLLVALFMLLY----Y 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1256 AFS---AICALMHDLLATCAVLVALHFflqriQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRREKLftPMPILINDAL 1332
Cdd:COG0342 293 RLPglvANIALALNVVLLLGVLSLLGA-----TLTLPGIAGIILTIGMAVDANVLIFERIREELRAGR--SLRAAIEAGF 365
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505318680 1333 QKTLgRTVMTT-ATTLSVLVILLFVGGGSIFNFAFIMTVGILLGTLSSLYIAPPLLLFMVRKEEQNSL 1399
Cdd:COG0342 366 KRAF-STILDAnVTTLIAAVVLFVLGTGPVKGFAVTLILGILISMFTAVPVTRPLLNLLLGRRRLKKL 432
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
1219-1395 |
2.95e-06 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 51.78 E-value: 2.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1219 KVSGQLSNKMRTQAVIALFGALGIILLYVSLRFE-WRYAFSAICALmhdLLATCAVLVALHFFLQRIQIDLQAIGALMTV 1297
Cdd:COG1033 207 VLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRsLRGVLLPLLVV---LLAVIWTLGLMGLLGIPLSPLTILVPPLLLA 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1298 LGysLNNTLIIFDRIREDRREKLftpmpiLINDALQKTLGRT----VMTTATTLSVLVILLFVGGGSIFNFAFIMTVGIL 1373
Cdd:COG1033 284 IG--IDYGIHLLNRYREERRKGL------DKREALREALRKLgppvLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVL 355
|
170 180
....*....|....*....|..
gi 505318680 1374 LGTLSSLYIAPPLLLFMVRKEE 1395
Cdd:COG1033 356 LAFLTSLTLLPALLSLLPRPKP 377
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
924-1048 |
5.50e-06 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 51.01 E-value: 5.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 924 YYRFGGVIASIAV-LLNLLLIWASMQYLDAPLTLSGLAGIILAMGMAVD-----ANVLVFERIREEYLLtrslsesveag 997
Cdd:COG4258 660 LRSLRRALRVLLPpLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDyalffTEGLLDKGELARTLL----------- 728
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 505318680 998 ykkafsAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTALFM 1048
Cdd:COG4258 729 ------SILLAALTTLLGFGLLAFSSTPALRSFGLTVLLGILLALLLAPLL 773
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
954-1055 |
6.70e-06 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 50.61 E-value: 6.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 954 LTLSGLAGIILAMGMavDANVLVFERIREEyLLTRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALT 1033
Cdd:TIGR00921 621 LAMATTISIILGLGM--DYSIHLAERYFEE-RKEHGPKEAITHTMERTGPGILFSGLTTAGGFLSLLLSHFPIMRNFGLV 697
|
90 100
....*....|....*....|..
gi 505318680 1034 LIIGIFSSMFTALFMTKFFFVI 1055
Cdd:TIGR00921 698 QGIGVLSSLTAALVVFPALLVL 719
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1231-1395 |
2.12e-05 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 49.33 E-value: 2.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1231 QAVIALFGALGIILLYVSLRFE-WRYAFSAICALmhdLLATCAVLVALhfFLQRIQIDLQA-IGALMTVlGYSLNNTLII 1308
Cdd:COG0841 852 SLGLAFLLALLLVYLVLAAQFEsFIQPLIILLTV---PLALIGALLGL--LLTGTPLNIYSqIGLIMLI-GIVVKNAILL 925
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1309 FDRIREDRREKlftpMPILinDALQKTlGRT-----VMTTATT-LSVLVILLFVGGGSIFNFAFIMTV--GILLGTLSSL 1380
Cdd:COG0841 926 VDFANQLREEG----MSLR--EAILEA-ARLrlrpiLMTSLATiLGLLPLALGTGAGAEFRQPLGIAVigGLLFSTLLTL 998
|
170
....*....|....*
gi 505318680 1381 YIAPPLLLFMVRKEE 1395
Cdd:COG0841 999 FVVPVLYVLLDRLRR 1013
|
|
| SecF |
COG0341 |
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ... |
886-1045 |
1.17e-04 |
|
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440110 [Multi-domain] Cd Length: 291 Bit Score: 45.81 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 886 PEILSEEVVSPELGSSQRVQGILSVVLGLVVLIVLMSVYYRFG-GVIASIAVLLNLLLIWASMQYLDAPLTLSGLAGIIL 964
Cdd:COG0341 115 VEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRFEWRfAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALLT 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 965 AMGMAVDANVLVFERIREEYLLTRslsesveagyKKAFSAIFDS------------NLTTILASALLLMLDTGPIKGFAL 1032
Cdd:COG0341 195 IIGYSLNDTVVVFDRIRENLRKYR----------KMTLAEIINLsinqtlsrtintSLTTLLVVLALLFFGGETLRDFAL 264
|
170
....*....|....*..
gi 505318680 1033 TLIIGI----FSSMFTA 1045
Cdd:COG0341 265 ALLIGIivgtYSSIFIA 281
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
930-1046 |
1.27e-04 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 45.75 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 930 VIASIAVLLNLLLIWasmQYLDApLTLSGLAGIIL-AMGMAV--DANVLVFERIREEylltRSLSESVEAGYKKAF---- 1002
Cdd:pfam03176 176 VGLSLGAAQGLVAIL---AHILG-IGLSTFALNLLvVLLIAVgtDYALFLVSRYREE----LRAGEDREEAVIRAVrgtg 247
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 505318680 1003 SAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTAL 1046
Cdd:pfam03176 248 KVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVDVLAAL 291
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
930-1049 |
2.44e-04 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 45.87 E-value: 2.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 930 VIASIAVLLNLLLIWASMQYLDAPL-TLSgLAGIILAMGMAVDA------NVlvfERIREEYLltrSLSESVEAGYKKAF 1002
Cdd:COG0841 359 LIPAVAIPVSLIGTFAVMYLLGFSLnILT-LFALVLAIGIVVDDaivvveNI---ERHMEEGL---SPLEAAIKGAREVA 431
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 505318680 1003 SAIFDSNLTTILASALLLMLD--TGPI-KGFALTLIIGIFSSMFTALFMT 1049
Cdd:COG0841 432 GAVIASTLTLVAVFLPLAFMGgiTGQLfRQFALTVAIALLISLFVALTLT 481
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
1231-1400 |
2.61e-04 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 45.22 E-value: 2.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1231 QAVIALFGALGIILLYVSLRFewRYA-FSAICALMHDLLATCAVLVALHFFLqriqiDLQAIGALMTVLGYSLNNTLIIF 1309
Cdd:PRK05812 298 AGLIAGLIGLALVLLFMILYY--RLFgLIANIALVANLVLILAVLSLLGATL-----TLPGIAGIVLTIGMAVDANVLIF 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1310 DRIREDRREklftpmpilindalqktlGRTV-----------MTT-----ATTLSVLVILLFVGGGSIFNFAFIMTVGIL 1373
Cdd:PRK05812 371 ERIREELRE------------------GRSLrsaieagfkraFSTildsnITTLIAAIILYALGTGPVKGFAVTLGIGIL 432
|
170 180
....*....|....*....|....*...
gi 505318680 1374 LGTLSSLYIAPPLL-LFMVRKEEQNSLR 1400
Cdd:PRK05812 433 TSMFTAITVTRALVnLLYGRRKRLKKLS 460
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
1199-1383 |
5.49e-04 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 44.77 E-value: 5.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1199 SDSGSSTTSMVFDAS-RGSWFKVSG------QLSNKMRTQAVIALfGALGIILLYVSLRFewrYAFSAICALMHDLLATC 1271
Cdd:NF037998 407 TETIARTIEALINQTtSGFTFKVNGisefnpVVTLLMLIASIIFL-LILAIAIMIYLLFA---YRLLGLFAIIIALTSIS 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1272 AVLVALHFFlqRIQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRREK---LFTPMPIlindALQKTLGRTVMTTATTLS 1348
Cdd:NF037998 483 LTLYSPTWF--GLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLYKNkrsIEESFKI----ANKETIGIIVDALVVLLI 556
|
170 180 190
....*....|....*....|....*....|....*
gi 505318680 1349 VLVILLFVGGGSIFNFAFIMTVGILLGTLSSLYIA 1383
Cdd:NF037998 557 PNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVA 591
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
930-1049 |
1.03e-03 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 43.82 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 930 VIASIAVLLNLLLIWASMQYLDAPLTLSGLAGIILAMGMAVDANVLVFERIrEEYLLTRSLSEsVEAGYKKA----FSAI 1005
Cdd:pfam00873 359 LIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVVDDAIVVVENI-ERVLEENGLKP-LEAAYKSMgeigGALV 436
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 505318680 1006 FdsnLTTILASALLLMLDTGPIKG-----FALTLIIGIFSSMFTALFMT 1049
Cdd:pfam00873 437 A---IALVLSAVFLPILFLGGLTGrifrqFAITIVLAILLSVLVALTLT 482
|
|
| PRK08578 |
PRK08578 |
preprotein translocase subunit SecF; Reviewed |
883-1047 |
1.96e-03 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 236302 [Multi-domain] Cd Length: 292 Bit Score: 41.84 E-value: 1.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 883 SFIPEILSEEVVSPELGSSQRVQGILSVVLGLVVlivlMS--VYYRFGGVIASIAVLL----NLLLIWASMQYLDAPLTL 956
Cdd:PRK08578 113 SISELNYSEKQIGPTFGSQFQEQALKAVGFAFIG----MAvvVFLIFRTPVPSLAVILsafsDIIIALALMNLFGIELSL 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 957 SGLAGIILAMGMAVDANVLVFERIreeylLTRslSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGP----IKGFAL 1032
Cdd:PRK08578 189 ATVAALLMLIGYSVDSDILLTTRV-----LKR--RGTFDESIKRAMRTGITMTLTTIAAMAVLYIVSTIPqaevLANIAA 261
|
170
....*....|....*.
gi 505318680 1033 TLIIGIFSS-MFTALF 1047
Cdd:PRK08578 262 VLIFGLLADlMNTWLL 277
|
|
| secD |
PRK08343 |
preprotein translocase subunit SecD; Reviewed |
1192-1377 |
2.47e-03 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 236245 [Multi-domain] Cd Length: 417 Bit Score: 42.17 E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1192 ARVLQVLSDSGSSTTSMVFDASrgswFKVSGQLSNKMRTQAVIALFGALGIILLYVSLRF-EWRYAFSaicalmhdLLAT 1270
Cdd:PRK08343 227 AKELYIHLRSGALPVKLDIEGS----GSVSPSLGEQFKKGSLIAGLLALLAVALVVFLRYrEPRIALP--------MVIT 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 1271 CA--VLVALHFF-LQRIQIDLQAIGALMTVLGYSLNNTLIIFDRI---REDRREKLFtpmpilindalQKTLGRT---VM 1341
Cdd:PRK08343 295 SLseVIIILGFAaLIGWQLDLASIAGIIAVIGTGVDDLIIITDEVlheGKVPSRKVF-----------LSRIKRAffiIF 363
|
170 180 190
....*....|....*....|....*....|....*..
gi 505318680 1342 TTATTLSVLVILLFVGG-GSIFNFAFIMTVGILLGTL 1377
Cdd:PRK08343 364 AAAATTIAAMSPLAVMGlGDLKGFAITTILGVLIGVL 400
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
930-1049 |
3.24e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 41.93 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505318680 930 VIASIAVLLNLLLIWASMQYLDAPLTLSGLAGIILAMGMAVDANVLVFERIreeyllTRSLSES---VEAGYKKA----F 1002
Cdd:NF033617 358 LIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVVENI------HRHIEEGespLEAALKGAreigF 431
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 505318680 1003 SAIfdsNLTTILASALLLMLDTGPIKG-----FALTLIIGIFSSMFTALFMT 1049
Cdd:NF033617 432 TVI---AMTLTLVAVYLPILFMGGLTGrlfreFAVTLAGAVIISGIVALTLT 480
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
1017-1061 |
6.42e-03 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 41.30 E-value: 6.42e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 505318680 1017 ALLLMLDTGPIKGFALTLIIGIFSSMFTALFMTkFFFVIWVQKTR 1061
Cdd:NF037998 1166 AIILAATLPSIVGFGITLLIGVVVAMFVTLFLA-VPLWVWLEKRR 1209
|
|
| |
