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Conserved domains on  [gi|505914786|ref|WP_015715081|]
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MULTISPECIES: PH domain-containing protein [Bacillus]

Protein Classification

PH domain-containing protein( domain architecture ID 11975562)

pleckstrin homology (PH) domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
bPH_4 pfam06713
Bacterial PH domain; This family consists of several hypothetical proteins specific to ...
 61-136 1.39e-18

Bacterial PH domain; This family consists of several hypothetical proteins specific to Oceanobacillus and Bacillus species. Members of this family are typically around 130 residues in length. The function of this family is unknown. Members of this family have a PH domain like structure.


:

Pssm-ID: 369049  Cd Length: 74  Bit Score: 74.57  E-value: 1.39e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505914786   61 KYVLKEHHLIIKAGLIKHQIPYEKIDKVVQKKKLWSgfRLIGSRHAITIYYQeGWGHAVISPQKSEEFIHKLKEKN 136
Cdd:pfam06713   2 KYILTEGTLIIKSGFFKKKIPIEDITKIRKTKSPLS--SPALSLDRLEIKYG-KYDTILISPKDKEEFIKLLKKRN 74
YdbT super family cl28701
Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain ...
 1-85 3.47e-05

Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


The actual alignment was detected with superfamily member COG3428:

Pssm-ID: 442654 [Multi-domain]  Cd Length: 410  Bit Score: 42.39  E-value: 3.47e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505914786   1 MVYQTKRDVPVTLMIVFLILLIQADAIVPFVLGNMRVSG---WIIFILLTLLNGLIIWSFID---LKYVLKEHHLIIKAG 74
Cdd:COG3428    1 MSEPWRRLHPLSILVRLLKALALLLPVLLLLLAGVGAGGgllWVLLIALVLLLLLLLVSYLRwrtTRYRITDDRLIVRSG 80

                         90
                 ....*....|....
gi 505914786  75 LI---KHQIPYEKI 85
Cdd:COG3428   81 VLsrkRREIPLDRI 94
 
Name Accession Description Interval E-value
bPH_4 pfam06713
Bacterial PH domain; This family consists of several hypothetical proteins specific to ...
 61-136 1.39e-18

Bacterial PH domain; This family consists of several hypothetical proteins specific to Oceanobacillus and Bacillus species. Members of this family are typically around 130 residues in length. The function of this family is unknown. Members of this family have a PH domain like structure.


Pssm-ID: 369049  Cd Length: 74  Bit Score: 74.57  E-value: 1.39e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505914786   61 KYVLKEHHLIIKAGLIKHQIPYEKIDKVVQKKKLWSgfRLIGSRHAITIYYQeGWGHAVISPQKSEEFIHKLKEKN 136
Cdd:pfam06713   2 KYILTEGTLIIKSGFFKKKIPIEDITKIRKTKSPLS--SPALSLDRLEIKYG-KYDTILISPKDKEEFIKLLKKRN 74
YdbT COG3428
Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain ...
 1-85 3.47e-05

Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


Pssm-ID: 442654 [Multi-domain]  Cd Length: 410  Bit Score: 42.39  E-value: 3.47e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505914786   1 MVYQTKRDVPVTLMIVFLILLIQADAIVPFVLGNMRVSG---WIIFILLTLLNGLIIWSFID---LKYVLKEHHLIIKAG 74
Cdd:COG3428    1 MSEPWRRLHPLSILVRLLKALALLLPVLLLLLAGVGAGGgllWVLLIALVLLLLLLLVSYLRwrtTRYRITDDRLIVRSG 80

                         90
                 ....*....|....
gi 505914786  75 LI---KHQIPYEKI 85
Cdd:COG3428   81 VLsrkRREIPLDRI 94
 
Name Accession Description Interval E-value
bPH_4 pfam06713
Bacterial PH domain; This family consists of several hypothetical proteins specific to ...
 61-136 1.39e-18

Bacterial PH domain; This family consists of several hypothetical proteins specific to Oceanobacillus and Bacillus species. Members of this family are typically around 130 residues in length. The function of this family is unknown. Members of this family have a PH domain like structure.


Pssm-ID: 369049  Cd Length: 74  Bit Score: 74.57  E-value: 1.39e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505914786   61 KYVLKEHHLIIKAGLIKHQIPYEKIDKVVQKKKLWSgfRLIGSRHAITIYYQeGWGHAVISPQKSEEFIHKLKEKN 136
Cdd:pfam06713   2 KYILTEGTLIIKSGFFKKKIPIEDITKIRKTKSPLS--SPALSLDRLEIKYG-KYDTILISPKDKEEFIKLLKKRN 74
YdbT COG3428
Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain ...
 1-85 3.47e-05

Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


Pssm-ID: 442654 [Multi-domain]  Cd Length: 410  Bit Score: 42.39  E-value: 3.47e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505914786   1 MVYQTKRDVPVTLMIVFLILLIQADAIVPFVLGNMRVSG---WIIFILLTLLNGLIIWSFID---LKYVLKEHHLIIKAG 74
Cdd:COG3428    1 MSEPWRRLHPLSILVRLLKALALLLPVLLLLLAGVGAGGgllWVLLIALVLLLLLLLVSYLRwrtTRYRITDDRLIVRSG 80

                         90
                 ....*....|....
gi 505914786  75 LI---KHQIPYEKI 85
Cdd:COG3428   81 VLsrkRREIPLDRI 94
bPH_5 pfam10882
Bacterial PH domain; This family of proteins with unknown function appear to be related to ...
 60-136 7.69e-03

Bacterial PH domain; This family of proteins with unknown function appear to be related to bacterial PH domains. This family was formerly known as DUF2679.


Pssm-ID: 378504  Cd Length: 100  Bit Score: 33.77  E-value: 7.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505914786   60 LKYVLKEHHLIIKAGLIKHQIPYEKIDKVVQKKKLWSGFRLIGSR-----------HAITIYY------------QEGWG 116
Cdd:pfam10882   1 LRYSLDDEGLVIRWIFGKVKIPLSDIEAVRVVEGVIKGVRLFGTGkpgyalgrfyiHDIGIAYmyatrlkrvlllKTKDK 80

                          90       100
                  ....*....|....*....|
gi 505914786  117 HAVISPQKSEEFIHKLKEKN 136
Cdd:pfam10882  81 IYGISPENFEEFKEALESRL 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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