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Conserved domains on  [gi|521257601|ref|WP_020444166|]
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MULTISPECIES: thioesterase family protein [unclassified Psychrobacter]

Protein Classification

thioesterase family protein( domain architecture ID 12150045)

thioesterase family protein similar to Talaromyces wortmannii thioesterase-like protein TwmA, part of the gene cluster that mediates the biosynthesis of wortmanamides A and B, reduced long-chain polyketides amidated with a specific omega-amino acid, 5-aminopentanoic acid (5PA)

CATH:  3.10.129.90

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
4HBT_3 pfam13622
Thioesterase-like superfamily; This family contains a wide variety of enzymes, principally ...
 38-266 2.41e-24

Thioesterase-like superfamily; This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.


:

Pssm-ID: 463937 [Multi-domain]  Cd Length: 246  Bit Score: 97.79  E-value: 2.41e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521257601   38 HMAPATGLLTAELQSFIPQENmrIARISLDILGLIPLDDFIVTTRCIRPGRTIELIEAVMSSRGRDAIIARAWRLITQDT 117
Cdd:pfam13622  12 HGGYVAALLLRAAERTVPPDP--LHSLHVDFLRPVPPGPVTIRVEVVRDGRSFSTRRVELSQDGRVVVTATATFGRLRSS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521257601  118 SVIAGLEDQKSIYKPEALP------AWDGMKGWPG--GFIESVRLVAEPNRRPGKG---MVWMTndidMVEGMPTHDMVH 186
Cdd:pfam13622  90 EWELTPAAPPPLPPPEDCPlaadeaPFPLFRRVPGflDPFEPRFARGGGPFSPGGPgrvRLWVR----LRDGGEPDPLAA 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521257601  187 LLGMADTANGVVPRLGLGMAKLeWMFPNTDLQIHMHRAP-QGRWLGIEAVQQYGADGIGISSAILHDTQG-PFGRSEQIL 264
Cdd:pfam13622 166 LAYLADAFPPRVLSLRLDPPAS-GWFPTLDLTVYFHRRPpPGEWLLLRAETPVAGDGRGDVEARLWDEDGrLVATSRQEV 244


                  ..
gi 521257601  265 TI 266
Cdd:pfam13622 245 LV 246
 
Name Accession Description Interval E-value
4HBT_3 pfam13622
Thioesterase-like superfamily; This family contains a wide variety of enzymes, principally ...
 38-266 2.41e-24

Thioesterase-like superfamily; This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.


Pssm-ID: 463937 [Multi-domain]  Cd Length: 246  Bit Score: 97.79  E-value: 2.41e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521257601   38 HMAPATGLLTAELQSFIPQENmrIARISLDILGLIPLDDFIVTTRCIRPGRTIELIEAVMSSRGRDAIIARAWRLITQDT 117
Cdd:pfam13622  12 HGGYVAALLLRAAERTVPPDP--LHSLHVDFLRPVPPGPVTIRVEVVRDGRSFSTRRVELSQDGRVVVTATATFGRLRSS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521257601  118 SVIAGLEDQKSIYKPEALP------AWDGMKGWPG--GFIESVRLVAEPNRRPGKG---MVWMTndidMVEGMPTHDMVH 186
Cdd:pfam13622  90 EWELTPAAPPPLPPPEDCPlaadeaPFPLFRRVPGflDPFEPRFARGGGPFSPGGPgrvRLWVR----LRDGGEPDPLAA 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521257601  187 LLGMADTANGVVPRLGLGMAKLeWMFPNTDLQIHMHRAP-QGRWLGIEAVQQYGADGIGISSAILHDTQG-PFGRSEQIL 264
Cdd:pfam13622 166 LAYLADAFPPRVLSLRLDPPAS-GWFPTLDLTVYFHRRPpPGEWLLLRAETPVAGDGRGDVEARLWDEDGrLVATSRQEV 244


                  ..
gi 521257601  265 TI 266
Cdd:pfam13622 245 LV 246
 
Name Accession Description Interval E-value
4HBT_3 pfam13622
Thioesterase-like superfamily; This family contains a wide variety of enzymes, principally ...
 38-266 2.41e-24

Thioesterase-like superfamily; This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.


Pssm-ID: 463937 [Multi-domain]  Cd Length: 246  Bit Score: 97.79  E-value: 2.41e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521257601   38 HMAPATGLLTAELQSFIPQENmrIARISLDILGLIPLDDFIVTTRCIRPGRTIELIEAVMSSRGRDAIIARAWRLITQDT 117
Cdd:pfam13622  12 HGGYVAALLLRAAERTVPPDP--LHSLHVDFLRPVPPGPVTIRVEVVRDGRSFSTRRVELSQDGRVVVTATATFGRLRSS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521257601  118 SVIAGLEDQKSIYKPEALP------AWDGMKGWPG--GFIESVRLVAEPNRRPGKG---MVWMTndidMVEGMPTHDMVH 186
Cdd:pfam13622  90 EWELTPAAPPPLPPPEDCPlaadeaPFPLFRRVPGflDPFEPRFARGGGPFSPGGPgrvRLWVR----LRDGGEPDPLAA 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521257601  187 LLGMADTANGVVPRLGLGMAKLeWMFPNTDLQIHMHRAP-QGRWLGIEAVQQYGADGIGISSAILHDTQG-PFGRSEQIL 264
Cdd:pfam13622 166 LAYLADAFPPRVLSLRLDPPAS-GWFPTLDLTVYFHRRPpPGEWLLLRAETPVAGDGRGDVEARLWDEDGrLVATSRQEV 244


                  ..
gi 521257601  265 TI 266
Cdd:pfam13622 245 LV 246
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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