|
Name |
Accession |
Description |
Interval |
E-value |
| T4SS-DNA_transf |
pfam02534 |
Type IV secretory system Conjugative DNA transfer; These proteins contain a P-loop and ... |
101-575 |
4.24e-161 |
|
Type IV secretory system Conjugative DNA transfer; These proteins contain a P-loop and walker-B site for nucleotide binding. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. The C-terminus of this domain interacts with the relaxosome component TraM via the latter's tetramerization domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore. The family contains a number of different DNA transfer proteins.
Pssm-ID: 367119 [Multi-domain] Cd Length: 468 Bit Score: 469.19 E-value: 4.24e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 101 KFASDNDLRKSKLLKWEKENDTDILVGAYKGKY---LWYTAPDF--VSLGAGTRAGKGAAIGIPNLLVRKHSLIALDPKQ 175
Cdd:pfam02534 1 RWANDGDLESAGLLTRENTIIGDVYTKDPDAWYaggLLNTDGDFshVLVFAGTGSGKGVGVVIPNLLVWKGSIVVLDPKG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 176 ELWKITSKVREiLLGNKVYLLDPFNSKTHQ-FNPLFYIDLKAESGAKDLLKLIEILFPSYGMtGAEAHFNNLAGQYWTGL 254
Cdd:pfam02534 81 ELWELTSGIRE-KQGRKVFVLEPFNPKTSDrYNPLDYIDRGSEQETEDILKVASLIMPGKGG-GRDDFFNNTARQLLVAL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 255 akllhfFINYEPSwlnefglKPVFSIGSVVDLYSNIDRELILSKREELEGTngLDENALYHLRDALTKIREYHETEDEQR 334
Cdd:pfam02534 159 ------IALVLRS-------KPTRTIGQTLRFVRNMLSEPNLIENKELAVL--LNELDGSHHDRVGDNLRFYVNKTDETR 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 335 SSIDGSFRKKMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNAEDISLAYDFLNLFFNFVVEVTLRENPDFDPTLKH 414
Cdd:pfam02534 224 SSVIGTAVSELALYADPEVRNATSGSDFDLRDLRRDKTSVYVILNPKDLTVVSPLLRVFFQMVVELLYLKLPNGDGRPKE 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 415 dCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQNISQLNEIYGIEGAKTLMSAHPCRIIYAVSE-EDDAAKISEKL 493
Cdd:pfam02534 304 -VLFLLDEFPSLGKLEILEEALATIRGYGIRLTTICQSISQLKETYGGEGAKSILSNHAVVICFAASNdEETAKYISKLL 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 494 GYI-TTTSKSTSKSRGRSTSQGESESEARRALVLPQELGTLDFKEEFIILKGENPVKAEKALYYLDPYFMDRLMKISPKL 572
Cdd:pfam02534 383 GKTtVEVESSSKSTDAKGSSRSRSISEVQRPLLTPDEVLRMPDDEQIVITKGQPPIKCKKALYFKDEDFKAELNKPTALT 462
|
...
gi 571061325 573 ASL 575
Cdd:pfam02534 463 ASV 465
|
|
| VirD4 |
COG3505 |
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, ... |
146-571 |
1.84e-86 |
|
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442728 [Multi-domain] Cd Length: 402 Bit Score: 274.94 E-value: 1.84e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 146 AGTRAGKGAAIGIPNL--LVRKHSLIALDPKQELWKITSKVREiLLGNKVYLLDPFN-SKTHQFNPLFYIDlkaesGAKD 222
Cdd:COG3505 6 GPTGSGKTVGLVIPNLtqLARGESVVVTDPKGDLAELTAGFRR-RAGYDVYVFDPFDpERSHRWNPLDEIR-----DPAD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 223 LLKLIEILFPS-YGMTGAEAHFNNLAGQYWTGLAKLLHffinyepswlnefgLKPVFSIGSVVDLYSNIDRELilskREE 301
Cdd:COG3505 80 AQELAEALIPAlGGGGGGDPFWREAARALLAALILALA--------------EEGRRTLADVYRLLSEPEEEL----REL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 302 LEGtngLDENALYHLRDALtkiREYHETEDEQRSSIDGSFRKKMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNAE 381
Cdd:COG3505 142 LEA---LPESPHPPVADTL---AAFLNAAEKTRSSVLSTLASALELLSDPEVAALTSGSDFDLRDLIREKGTLYLVLPPD 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 382 DISLAYDFLNLFFNFVVEVTLRENPDFDPtLKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQNISQLNEIYG 461
Cdd:COG3505 216 DLSTLAPLLRLLLSQLIRALLRRAERSGR-LPRPVLLLLDEFANLGRLPSLETLLATGRGYGIRLVLILQSLAQLEAIYG 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 462 IEGAKTLMSAHPCRIIYAVSEEDDAAKISEKLGYITTTSKSTSKSRGrstSQGESESEARRALVLPQELGTLDFKEEFII 541
Cdd:COG3505 295 EEGAETILGNCGTKIFLGVNDPETAEYLSELLGKRTVERRSESRSRG---SRSRSRSEQERPLLTPDELRRLPDGEAIVL 371
|
410 420 430
....*....|....*....|....*....|
gi 571061325 542 LKGENPVKAEKALYYLDPYFMDRLMKISPK 571
Cdd:COG3505 372 VRGGPPIRAKKIRYYKDPEPAPAFEPRDAE 401
|
|
| PRK13897 |
PRK13897 |
type IV secretion system component VirD4; Provisional |
12-567 |
2.58e-40 |
|
type IV secretion system component VirD4; Provisional
Pssm-ID: 237549 [Multi-domain] Cd Length: 606 Bit Score: 155.34 E-value: 2.58e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 12 AFIGLVMCLvtYYTGSVAVYFLNGKTPL---YIWKNFDS--MLLWRIITE--SNIRTDIRLTAiPSLLSGMVSSLIVPVF 84
Cdd:PRK13897 19 HFVVLEFCF--YISGAFFALFTWGPGALdfnAINPSIADfpWAYWPTIFNyiINVWGQPKIYD-YNLKLKLLASLLGPAI 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 85 II-------------WQLNKTDVALYGDAKFASDNDLRKSKLlkwekENDTDILVGAYKGKYLWYTAPDFVSLGAGTRAG 151
Cdd:PRK13897 96 IViifyiklreriksWRPFKKKEKVHGDARWASESDIRKAGL-----RSKKGMLLGKDKGGYFVADGFQHALLFAPTGSG 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 152 KGAAIGIPNLLVRKHSLIALDPKQELWKITSKVREiLLGNKVYLLDPFN--SKTHQFNPLFYIDLKAESGAKDLLKLIEI 229
Cdd:PRK13897 171 KGVGFVIPNLLFWEDSVVVHDIKLENYELTSGWRE-KQGQKVFVWEPANpdGISHCYNPLDWVSTKPGQMVDDVQKIANL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 230 LFPsygmtgaEAHF-NNLAGQYWTGLAkllhFFINYEPSWLNEFGL--------KPVFSIGSVVDLYSNIDRELilskre 300
Cdd:PRK13897 250 IMP-------EQDFwNNEARSLFLGVV----LYLLADPEKVKSFGEvvrtmrsdDVVYNLAVVLDTLGKVIHPV------ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 301 elegtngldenalyhlrdALTKIREYHETEDEQRSSIDGSFRKKMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNA 380
Cdd:PRK13897 313 ------------------AYMNIAAFLQKADKERSGVISTMNSSLELWANPLIDTATASSDFNIQEFKKKKTTVYVGLTP 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 381 EDISLAYDFLNLFFNFVVEVTLRENPDFDPtlKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQNISQLNEIY 460
Cdd:PRK13897 375 DNLTRLQPLMQVFYQQATEFLCRKLPDKDE--PYGVLFLMDEFPTLGKMEQFKTGIAYFRGYRVRLFLIIQDTEQLKGIY 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 461 GIEGAKTLMSAHPCRIIYAVSEEDDAAKISEKLGYITTTSKSTSKSRG---RSTSQGESESEARRALVLPQELGTLDFKE 537
Cdd:PRK13897 453 EEAGMNSFLSNSTYRITFAANNIETANLISQLVGNKTVEQESLNKPKFldlNPASRSLHISEVQRALLLPQEVIMLPRDE 532
|
570 580 590
....*....|....*....|....*....|
gi 571061325 538 EFIILKGENPVKAEKALYYLDPYFMDRLMK 567
Cdd:PRK13897 533 QILLIESTYPIKSKKIKYYEDKFFTSRLLP 562
|
|
| TrwB_TraG_TraD_VirD4 |
cd01127 |
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ... |
373-480 |
4.66e-12 |
|
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain] Cd Length: 144 Bit Score: 63.78 E-value: 4.66e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 373 TVYVGVNAEDISlAYDFLNLFFNFVVEVTLRENPDFDPTLKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQN 452
Cdd:cd01127 38 ELFLVIPDRDDS-FAALRALFFNQLFRALTELASLSPGRLPRRVWFILDEFANLGRIPNLPNLLATGRKRGISVVLILQS 116
|
90 100
....*....|....*....|....*...
gi 571061325 453 ISQLNEIYGIEGAKTLMSAHPCRIIYAV 480
Cdd:cd01127 117 LAQLEAVYGKDGAQTILGNCNTKLYLGT 144
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| T4SS-DNA_transf |
pfam02534 |
Type IV secretory system Conjugative DNA transfer; These proteins contain a P-loop and ... |
101-575 |
4.24e-161 |
|
Type IV secretory system Conjugative DNA transfer; These proteins contain a P-loop and walker-B site for nucleotide binding. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. The C-terminus of this domain interacts with the relaxosome component TraM via the latter's tetramerization domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore. The family contains a number of different DNA transfer proteins.
Pssm-ID: 367119 [Multi-domain] Cd Length: 468 Bit Score: 469.19 E-value: 4.24e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 101 KFASDNDLRKSKLLKWEKENDTDILVGAYKGKY---LWYTAPDF--VSLGAGTRAGKGAAIGIPNLLVRKHSLIALDPKQ 175
Cdd:pfam02534 1 RWANDGDLESAGLLTRENTIIGDVYTKDPDAWYaggLLNTDGDFshVLVFAGTGSGKGVGVVIPNLLVWKGSIVVLDPKG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 176 ELWKITSKVREiLLGNKVYLLDPFNSKTHQ-FNPLFYIDLKAESGAKDLLKLIEILFPSYGMtGAEAHFNNLAGQYWTGL 254
Cdd:pfam02534 81 ELWELTSGIRE-KQGRKVFVLEPFNPKTSDrYNPLDYIDRGSEQETEDILKVASLIMPGKGG-GRDDFFNNTARQLLVAL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 255 akllhfFINYEPSwlnefglKPVFSIGSVVDLYSNIDRELILSKREELEGTngLDENALYHLRDALTKIREYHETEDEQR 334
Cdd:pfam02534 159 ------IALVLRS-------KPTRTIGQTLRFVRNMLSEPNLIENKELAVL--LNELDGSHHDRVGDNLRFYVNKTDETR 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 335 SSIDGSFRKKMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNAEDISLAYDFLNLFFNFVVEVTLRENPDFDPTLKH 414
Cdd:pfam02534 224 SSVIGTAVSELALYADPEVRNATSGSDFDLRDLRRDKTSVYVILNPKDLTVVSPLLRVFFQMVVELLYLKLPNGDGRPKE 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 415 dCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQNISQLNEIYGIEGAKTLMSAHPCRIIYAVSE-EDDAAKISEKL 493
Cdd:pfam02534 304 -VLFLLDEFPSLGKLEILEEALATIRGYGIRLTTICQSISQLKETYGGEGAKSILSNHAVVICFAASNdEETAKYISKLL 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 494 GYI-TTTSKSTSKSRGRSTSQGESESEARRALVLPQELGTLDFKEEFIILKGENPVKAEKALYYLDPYFMDRLMKISPKL 572
Cdd:pfam02534 383 GKTtVEVESSSKSTDAKGSSRSRSISEVQRPLLTPDEVLRMPDDEQIVITKGQPPIKCKKALYFKDEDFKAELNKPTALT 462
|
...
gi 571061325 573 ASL 575
Cdd:pfam02534 463 ASV 465
|
|
| VirD4 |
COG3505 |
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, ... |
146-571 |
1.84e-86 |
|
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442728 [Multi-domain] Cd Length: 402 Bit Score: 274.94 E-value: 1.84e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 146 AGTRAGKGAAIGIPNL--LVRKHSLIALDPKQELWKITSKVREiLLGNKVYLLDPFN-SKTHQFNPLFYIDlkaesGAKD 222
Cdd:COG3505 6 GPTGSGKTVGLVIPNLtqLARGESVVVTDPKGDLAELTAGFRR-RAGYDVYVFDPFDpERSHRWNPLDEIR-----DPAD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 223 LLKLIEILFPS-YGMTGAEAHFNNLAGQYWTGLAKLLHffinyepswlnefgLKPVFSIGSVVDLYSNIDRELilskREE 301
Cdd:COG3505 80 AQELAEALIPAlGGGGGGDPFWREAARALLAALILALA--------------EEGRRTLADVYRLLSEPEEEL----REL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 302 LEGtngLDENALYHLRDALtkiREYHETEDEQRSSIDGSFRKKMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNAE 381
Cdd:COG3505 142 LEA---LPESPHPPVADTL---AAFLNAAEKTRSSVLSTLASALELLSDPEVAALTSGSDFDLRDLIREKGTLYLVLPPD 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 382 DISLAYDFLNLFFNFVVEVTLRENPDFDPtLKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQNISQLNEIYG 461
Cdd:COG3505 216 DLSTLAPLLRLLLSQLIRALLRRAERSGR-LPRPVLLLLDEFANLGRLPSLETLLATGRGYGIRLVLILQSLAQLEAIYG 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 462 IEGAKTLMSAHPCRIIYAVSEEDDAAKISEKLGYITTTSKSTSKSRGrstSQGESESEARRALVLPQELGTLDFKEEFII 541
Cdd:COG3505 295 EEGAETILGNCGTKIFLGVNDPETAEYLSELLGKRTVERRSESRSRG---SRSRSRSEQERPLLTPDELRRLPDGEAIVL 371
|
410 420 430
....*....|....*....|....*....|
gi 571061325 542 LKGENPVKAEKALYYLDPYFMDRLMKISPK 571
Cdd:COG3505 372 VRGGPPIRAKKIRYYKDPEPAPAFEPRDAE 401
|
|
| PRK13897 |
PRK13897 |
type IV secretion system component VirD4; Provisional |
12-567 |
2.58e-40 |
|
type IV secretion system component VirD4; Provisional
Pssm-ID: 237549 [Multi-domain] Cd Length: 606 Bit Score: 155.34 E-value: 2.58e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 12 AFIGLVMCLvtYYTGSVAVYFLNGKTPL---YIWKNFDS--MLLWRIITE--SNIRTDIRLTAiPSLLSGMVSSLIVPVF 84
Cdd:PRK13897 19 HFVVLEFCF--YISGAFFALFTWGPGALdfnAINPSIADfpWAYWPTIFNyiINVWGQPKIYD-YNLKLKLLASLLGPAI 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 85 II-------------WQLNKTDVALYGDAKFASDNDLRKSKLlkwekENDTDILVGAYKGKYLWYTAPDFVSLGAGTRAG 151
Cdd:PRK13897 96 IViifyiklreriksWRPFKKKEKVHGDARWASESDIRKAGL-----RSKKGMLLGKDKGGYFVADGFQHALLFAPTGSG 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 152 KGAAIGIPNLLVRKHSLIALDPKQELWKITSKVREiLLGNKVYLLDPFN--SKTHQFNPLFYIDLKAESGAKDLLKLIEI 229
Cdd:PRK13897 171 KGVGFVIPNLLFWEDSVVVHDIKLENYELTSGWRE-KQGQKVFVWEPANpdGISHCYNPLDWVSTKPGQMVDDVQKIANL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 230 LFPsygmtgaEAHF-NNLAGQYWTGLAkllhFFINYEPSWLNEFGL--------KPVFSIGSVVDLYSNIDRELilskre 300
Cdd:PRK13897 250 IMP-------EQDFwNNEARSLFLGVV----LYLLADPEKVKSFGEvvrtmrsdDVVYNLAVVLDTLGKVIHPV------ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 301 elegtngldenalyhlrdALTKIREYHETEDEQRSSIDGSFRKKMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNA 380
Cdd:PRK13897 313 ------------------AYMNIAAFLQKADKERSGVISTMNSSLELWANPLIDTATASSDFNIQEFKKKKTTVYVGLTP 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 381 EDISLAYDFLNLFFNFVVEVTLRENPDFDPtlKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQNISQLNEIY 460
Cdd:PRK13897 375 DNLTRLQPLMQVFYQQATEFLCRKLPDKDE--PYGVLFLMDEFPTLGKMEQFKTGIAYFRGYRVRLFLIIQDTEQLKGIY 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 461 GIEGAKTLMSAHPCRIIYAVSEEDDAAKISEKLGYITTTSKSTSKSRG---RSTSQGESESEARRALVLPQELGTLDFKE 537
Cdd:PRK13897 453 EEAGMNSFLSNSTYRITFAANNIETANLISQLVGNKTVEQESLNKPKFldlNPASRSLHISEVQRALLLPQEVIMLPRDE 532
|
570 580 590
....*....|....*....|....*....|
gi 571061325 538 EFIILKGENPVKAEKALYYLDPYFMDRLMK 567
Cdd:PRK13897 533 QILLIESTYPIKSKKIKYYEDKFFTSRLLP 562
|
|
| PRK13850 |
PRK13850 |
type IV secretion system protein VirD4; Provisional |
72-558 |
3.94e-36 |
|
type IV secretion system protein VirD4; Provisional
Pssm-ID: 237531 [Multi-domain] Cd Length: 670 Bit Score: 143.86 E-value: 3.94e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 72 LSGMVSSLIVPVFIIWQLNKTDVALYGDAKFASDNDLRKSKLLKWEKENDTDIL---VGAYK-GKYLWYTAPDFVSLGAG 147
Cdd:PRK13850 68 LAIVVSTSVVVLLSQLIVSLRNREHHGTARWAEEGEMRHAGYLQRYSRITGPIFgktCGPRWfGSYLTNGEQPHSLVVAP 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 148 TRAGKGAAIGIPNLLVRKHSLIALDPKQELWKITSKVREILlGNKVYLLDPFNS--KTHQFNPLFYI-DLKAESGAKDLL 224
Cdd:PRK13850 148 TRAGKGVGVVIPTLLTFKGSVIALDVKGELFELTSRARKAS-GDAVFKFAPLDPerRTHCYNPVLDIaALPPERRFTETR 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 225 KLIEILFPSYGmTGAEAHFNNLAGQYWTGLAKLLhffinyepswlnEFGLKpvfSIGSVVDLYSNIDRELILSKREELEG 304
Cdd:PRK13850 227 RLAANLITAKG-KGAEGFIDGARDLFVAGILACI------------ERGTP---TIGAVYDLFAQPGEKYKLFAQLAEET 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 305 TNGLDENALYHLRDALTKIREYHetedeqrSSI--DGSfrkkMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNAED 382
Cdd:PRK13850 291 QNKEAQRIFDNMAGNDTKILTSY-------TSVlgDGG----LNLWADPLVKAATSRSDFSVYDLRRKRTCIYLCVSPND 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 383 ISLAYDFLNLFFNFVVEVTLRENPDFDPtlKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQNISQLNEIYGI 462
Cdd:PRK13850 360 LEVVAPLMRLLFQQVVSILQRSLPGKDE--RHEVLFLLDEFKHLGKLEAIETAITTIAGYKGRFMFIIQSLSALTGTYDE 437
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 463 EGAKTLMSAHPCRIIYAVSEEDDAAKISEKLGyitttsksTSKSRGRSTSQGES--------ESEARRALVLPQELGTLD 534
Cdd:PRK13850 438 AGKQNFLSNTGVQVFMATADDETPTYISKAIG--------DYTFKARSTSYSQArmfdhniqISDQGAPLLRPEQVRLLD 509
|
490 500
....*....|....*....|....
gi 571061325 535 FKEEFIILKGENPVKAEKALYYLD 558
Cdd:PRK13850 510 DDTEIVLIKGQPPLKLRKVRYYSD 533
|
|
| PRK13880 |
PRK13880 |
conjugal transfer coupling protein TraG; Provisional |
72-456 |
1.08e-23 |
|
conjugal transfer coupling protein TraG; Provisional
Pssm-ID: 237540 Cd Length: 636 Bit Score: 105.59 E-value: 1.08e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 72 LSGMVSSLIVPVFIIWQlNKTDVALYGDAKFASDNDLRKSKLLKWEKEND-----------TDILVGAY---KGK--YLW 135
Cdd:PRK13880 93 TVGLLGVAVAKVVTSNS-SKANEYLHGSARWAEKKDIQAAGLLPRERNVLeivtgkaaptaTGVYVGGWqdkDGNfhYLR 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 136 YTAPDFVSLGAGTRAGKGAAIGIPNLLVRKHSLIALDPKQELWKITSKVREILLGNKVYLLDPFNSK-THQFNPLFYIDL 214
Cdd:PRK13880 172 HNGPEHVLTYAPTRSGKGVGLVVPTLLSWGHSSVITDLKGELWALTAGWRQKHAKNKVLRFEPASLSgSVCWNPLDEIRL 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 215 KAESGAKDLLKLIEILFPSYGmTGAEAHFNNLAGQYWTGLakLLHFFINYEpswlNEfglkpvfsiGSVVDLySNIDREL 294
Cdd:PRK13880 252 GTEYEVGDVQNLATLIVDPDG-KGLESHWQKTAFALLVGV--ILHALYKAK----NE---------GGTATL-PSVDAML 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 295 ILSKRE--ELegtngLDENALYHLRDALTKI------REYHETEDEQRSSIDGSFRKKMSLFYLPTVRKCTDGNDFDLRQ 366
Cdd:PRK13880 315 ADPNRDigEL-----WMEMTTYGHVDGQNHPaigsaaRDMMDRPEEEAGSVLSTAKSYLALYRDPVVARNVSRSDFRIKD 389
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 367 LRRED--ITVYVGVNAEDISLAYDFLNLFFNFVVEVtLRENPDFD-----PTLKHDCLMFLDEFPSIGYMPIIKKGSGYI 439
Cdd:PRK13880 390 LMHHDdpVSLYIVTQPNDKARLRPLVRVMVNMIVRL-LADKMDFEngrpvAHYKHRLLMMLDEFPSLGKLEILQESLAFV 468
|
410
....*....|....*..
gi 571061325 440 AGFKLKLLTIYQNISQL 456
Cdd:PRK13880 469 AGYGIKCYLICQDINQL 485
|
|
| TraG-D_C |
pfam12696 |
TraM recognition site of TraD and TraG; This family includes both TraG and TraD as well as ... |
416-535 |
6.85e-23 |
|
TraM recognition site of TraD and TraG; This family includes both TraG and TraD as well as VirD4 proteins. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. This domain interacts with the relaxosome component TraM via the latter's tetramerization domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore.
Pssm-ID: 432726 [Multi-domain] Cd Length: 125 Bit Score: 94.25 E-value: 6.85e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 416 CLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQNISQLNEIYGIEGAKTLMSAHPCRIIYAVSEEDDAAKISEKLGY 495
Cdd:pfam12696 2 VLFVLDEFANLGKIPDLEKLISTGRSRGISLMLILQSIAQLEELYGKDGAETILGNCNTKVFLGGGDEETAKYLSKLLGK 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 571061325 496 ITTTSKSTSKSRGRSTSQGE----SESEARRALVLPQELGTLDF 535
Cdd:pfam12696 82 YTVVSTTTSSSSSGSGGSGSssssSSQLVGRPLLTPDELRRLPR 125
|
|
| PRK13876 |
PRK13876 |
conjugal transfer coupling protein TraG; Provisional |
93-573 |
2.48e-18 |
|
conjugal transfer coupling protein TraG; Provisional
Pssm-ID: 237538 Cd Length: 663 Bit Score: 88.83 E-value: 2.48e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 93 DVALYGDAKFASDNDLRKSKLLKwekenDTDILVGAYKGKYLWYTAPDFVSLGAGTRAGKGAAIGIPNLLVRKHSLIALD 172
Cdd:PRK13876 103 RVTTYGSARWAERREIRAAGLLG-----PDGVVLGRHDRDYLRHDGPEHVLCFAPTRSGKGVGLVVPTLLTWPGSAIVHD 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 173 PKQELWKITSKVREILlgNKVYLLDPFNSKTHQFNPLFYIDlKAESGAKDLLKLIEILFPSYGMTGAEAHfnnlagqyW- 251
Cdd:PRK13876 178 IKGENWQLTAGFRARF--GRVLLFDPTNAKSAAYNPLLEVR-RGEWEVRDVQNIADILVDPEGSLERRNH--------We 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 252 -TGLAKL----LHffINY-EPSwlnefglKpvfSIGSVVDLYSNIDR--ELILSKreeLEGTNGLDENALYHL-----RD 318
Cdd:PRK13876 247 kTSHALLvgaiLH--VLYaEED-------K---TLAGVANFLSDPKRpiEATLRA---MMTTPHLGEAGPHPVvasaaRE 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 319 ALTKireyhetEDEQRSsidGSFRKKMS---LFYLPTVRKCTDGNDFDLRQL--RREDITVYVGVNAEDISLAYDFLNLF 393
Cdd:PRK13876 312 LLNK-------SDNERS---GVLSTAMSflgLYRDPVVAEVTSRCDWRIADLvaGERPVSLYLVVPPSDISRTKPLIRLI 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 394 FNFVVEvTLRENPDFDPTlKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQNISQLNEIYGIEGAkTLMSAHp 473
Cdd:PRK13876 382 LNQIGR-RLTEDLDGKAR-RHRLLLMLDEFPALGRLDFFESALAFMAGYGIKSFLIAQSLNQIEKAYGQNNS-ILDNCH- 457
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 474 CRIIYAVSEEDDAAKISEKLGyitttskSTSKSRGRSTSQG-----------ESESEARRALVLPQELGTLDFKEEFIIL 542
Cdd:PRK13876 458 VRVSFATNDERTAKRVSDALG-------TATELRAMKNYAGhrlspwlghlmVSRQETARPLLTPGEVMQLPPDDEIVMV 530
|
490 500 510
....*....|....*....|....*....|.
gi 571061325 543 KGENPVKAEKALYYLDPYFMDRLMKiSPKLA 573
Cdd:PRK13876 531 SGVPPIRAKKARYYEDARFKERVLP-PPDLA 560
|
|
| TrwB_AAD_bind |
pfam10412 |
Type IV secretion-system coupling protein DNA-binding domain; The plasmid conjugative coupling ... |
335-548 |
7.22e-13 |
|
Type IV secretion-system coupling protein DNA-binding domain; The plasmid conjugative coupling protein TrwB forms hexamers from six structurally very similar protomers. This hexamer contains a central channel running from the cytosolic pole (made up by the AADs) to the membrane pole ending at the transmembrane pore shaped by 12 transmembrane helices, rendering an overall mushroom-like structure. The TrwB_AAD (all-alpha domain) domain appears to be the DNA-binding domain of the structure. TrwB, a basic integral inner-membrane nucleoside-triphosphate-binding protein, is the structural prototype for the type IV secretion system coupling proteins, a family of proteins essential for macromolecular transport between cells and export.
Pssm-ID: 431268 [Multi-domain] Cd Length: 386 Bit Score: 70.40 E-value: 7.22e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 335 SSIDGSFRKKM-SLFYLPTvrkctDGNDFDLRQ-LRREDIT--VYVGVNAEDISLAYDFLNLFFNFVVEVTLRENPDFDP 410
Cdd:pfam10412 169 ASIRATLATNLrALRFLAP-----DGERFSIREwITEEDPGgwLFITYRADQRAALRPLLSCWLDLAIRALLSLPPSRDR 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 411 TLkhdcLMFLDEFPSIGYMPII--------KKGSGYIAGFklklltiyQNISQLNEIYGIEGAKTLMSAHPCRIIYAVSE 482
Cdd:pfam10412 244 RL----WFFLDELPALGRLPSLkdllaegrKFGGAVVLGL--------QSIAQLREIYGEDGAQTILSNCGTKLILRVSD 311
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 571061325 483 EDDAAKISEKLGYITTTSKSTSKSRGRSTSQ-GESESEAR--RALVLPQELGTLDFKEEFIILKGENPV 548
Cdd:pfam10412 312 GETAELCSDLLGDREVERMDESLSYGANNSRdGVTLGRQRrvRPLVLPSEIMNLPRLHGYLKFPDGFPV 380
|
|
| TrwB_TraG_TraD_VirD4 |
cd01127 |
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ... |
373-480 |
4.66e-12 |
|
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain] Cd Length: 144 Bit Score: 63.78 E-value: 4.66e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 373 TVYVGVNAEDISlAYDFLNLFFNFVVEVTLRENPDFDPTLKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQN 452
Cdd:cd01127 38 ELFLVIPDRDDS-FAALRALFFNQLFRALTELASLSPGRLPRRVWFILDEFANLGRIPNLPNLLATGRKRGISVVLILQS 116
|
90 100
....*....|....*....|....*...
gi 571061325 453 ISQLNEIYGIEGAKTLMSAHPCRIIYAV 480
Cdd:cd01127 117 LAQLEAVYGKDGAQTILGNCNTKLYLGT 144
|
|
| PRK13822 |
PRK13822 |
conjugal transfer coupling protein TraG; Provisional |
158-556 |
3.74e-10 |
|
conjugal transfer coupling protein TraG; Provisional
Pssm-ID: 237522 [Multi-domain] Cd Length: 641 Bit Score: 62.68 E-value: 3.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 158 IPNLLVRKHSLIALDPKQELWKITSKVREiLLGNKVYLLDPFNSKThQFNPLFYIDLKAESGAKDLLKLIE-ILFPSYGM 236
Cdd:PRK13822 243 VPTALKWGGPLVVLDPSTEVAPMVSEHRR-DAGREVIVLDPTNPGT-GFNVLDWIGRSGGTKEEDIVAVASwILSDSKRT 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 237 TGA-EAHFNNLAGQYWTGLakLLHFFIN--YEPSWLNefgLKPVfsigsvvdlysnidRElILSKREElegtngldenal 313
Cdd:PRK13822 321 ESSrDDFFRNSAHQLLTAL--LAHVCLSgeYEGKERT---LRTL--------------RA-ILSEPEP------------ 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 314 yHLRDALTKIREyHETEDEQRSSIdGSFrKKM-----SLFYlPTVRKCTD------------GNDFDLRQLRREDITVYV 376
Cdd:PRK13822 369 -SLRARLRDIYE-NSESDFIRENV-GVF-VNMteqtfSGVY-ATASKDTQwlsypnyaalvsGNSFSTSDLAAGNTDVFI 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 377 GVNAEDI----SLAYDFLNLFFNFVVEVtlrenpdfDPTLKHDCLMFLDEFPSIGYMPIIK----KGSGYiagfKLKLLT 448
Cdd:PRK13822 444 NIPLKILesypGLARVIIGSLLNAMYNA--------DGNVKGRALFLLDEVARLGYMRILEtardAGRKY----GITLML 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571061325 449 IYQNISQLNEIYGIEGAKTLMSAHPCRIIYAVSEEDDAAKISEKLGYITTTSKSTSKSRG-RSTSQGESESEARRALVLP 527
Cdd:PRK13822 512 IYQSIGQLREHFGGRGATSWFESASWISFAAIKDLDTADYISERCGEMTVEVDQTSRSSGwSGSSRSRSKQLQRRPLIMP 591
|
410 420 430
....*....|....*....|....*....|
gi 571061325 528 QE-LGTLDFKEEFIILKGENPVKAEKALYY 556
Cdd:PRK13822 592 HEiLQSMRADEQIIFVQGNPPLRCGRAIYF 621
|
|
| TrwB_TraG_TraD_VirD4 |
cd01127 |
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ... |
146-182 |
2.69e-03 |
|
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain] Cd Length: 144 Bit Score: 38.74 E-value: 2.69e-03
10 20 30
....*....|....*....|....*....|....*....
gi 571061325 146 AGTRAGKGAAIGIPNLLV--RKHSLIALDPKQELWKITS 182
Cdd:cd01127 6 GTTGSGKTTSIVIPLLDQaaRGGSVIITDPKGELFLVIP 44
|
|
| |
