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Conserved domains on  [gi|655512805|ref|WP_028893868|]
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FAD-dependent oxidoreductase [Syntrophorhabdus aromaticivorans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HdrA super family cl34141
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
2-306 1.37e-62

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


The actual alignment was detected with superfamily member COG1148:

Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 215.88  E-value: 1.37e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   2 NILVVGGGISGISAAKVALREGHDVTVIECTGEPGGLMARIancrvgFKTF-------------FDEIRDKPRLTVIRDA 68
Cdd:COG1148  142 RALVIGGGIAGMTAALELAEQGYEVYLVEKEPELGGRAAQL------HKTFpgldcpqcileplIAEVEANPNITVYTGA 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  69 RIAKVEKRENVFTVILEDG----QSIRADRVIIAAGLSPYDPV---EY---KGKRVLTSLEYDAVIDQRNGDLPADF--- 135
Cdd:COG1148  216 EVEEVSGYVGNFTVTIKKGpreeIEIEVGAIVLATGFKPYDPTklgEYgygKYPNVITNLELERLLAAGKILRPSDGkep 295

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 136 EKIGFFLCVGSRSKEYPL--CSSVCCSYTLREVKWtLQRAKPE--ITVFYNDLRFFGQeflMEKAY---RDAGVRFVRAN 208
Cdd:COG1148  296 KSVAFIQCVGSRDEENGLpyCSRVCCMYALKQALY-LKEKNPDadVYIFYRDIRTYGK---YEEFYrraREDGVRFIRGR 371

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 209 -SRYFEEDDDGVTVRYF--AAGGLKEERFNYAILAIGLRPNPELERLSGLFGFSRDEFGFAVEKE----PLKADADGVYL 281
Cdd:COG1148  372 vAEIEEDEGGKLVVTVEdtLLGEPVEIEADLVVLATGMVPSEDNEELAKLLKLPLDQDGFFLEAHpklrPVETATDGIFL 451

                        330       340
                 ....*....|....*....|....*
gi 655512805 282 AGGSIEPMSIKDAILTGFGAAMRAV 306
Cdd:COG1148  452 AGAAHGPKDIPESIAQATAAAARAI 476
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 504-576 7.90e-14

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


:

Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 66.29  E-value: 7.90e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 655512805 504 RILPEVSEDRCSGCGSCKEACPHDAIEMEMREQQValfgpnvvscapiahVKEGSCVGCGLCAATCPSHVISY 576
Cdd:COG1149    3 RKIPVIDEEKCIGCGLCVEVCPEGAIKLDDGGAPV---------------VDPDLCTGCGACVGVCPTGAITL 60
 
Name Accession Description Interval E-value
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
2-306 1.37e-62

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 215.88  E-value: 1.37e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   2 NILVVGGGISGISAAKVALREGHDVTVIECTGEPGGLMARIancrvgFKTF-------------FDEIRDKPRLTVIRDA 68
Cdd:COG1148  142 RALVIGGGIAGMTAALELAEQGYEVYLVEKEPELGGRAAQL------HKTFpgldcpqcileplIAEVEANPNITVYTGA 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  69 RIAKVEKRENVFTVILEDG----QSIRADRVIIAAGLSPYDPV---EY---KGKRVLTSLEYDAVIDQRNGDLPADF--- 135
Cdd:COG1148  216 EVEEVSGYVGNFTVTIKKGpreeIEIEVGAIVLATGFKPYDPTklgEYgygKYPNVITNLELERLLAAGKILRPSDGkep 295

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 136 EKIGFFLCVGSRSKEYPL--CSSVCCSYTLREVKWtLQRAKPE--ITVFYNDLRFFGQeflMEKAY---RDAGVRFVRAN 208
Cdd:COG1148  296 KSVAFIQCVGSRDEENGLpyCSRVCCMYALKQALY-LKEKNPDadVYIFYRDIRTYGK---YEEFYrraREDGVRFIRGR 371

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 209 -SRYFEEDDDGVTVRYF--AAGGLKEERFNYAILAIGLRPNPELERLSGLFGFSRDEFGFAVEKE----PLKADADGVYL 281
Cdd:COG1148  372 vAEIEEDEGGKLVVTVEdtLLGEPVEIEADLVVLATGMVPSEDNEELAKLLKLPLDQDGFFLEAHpklrPVETATDGIFL 451

                        330       340
                 ....*....|....*....|....*
gi 655512805 282 AGGSIEPMSIKDAILTGFGAAMRAV 306
Cdd:COG1148  452 AGAAHGPKDIPESIAQATAAAARAI 476
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 1-283 1.30e-14

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 74.66  E-value: 1.30e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805    1 MNILVVGGGISGISAAKVALREGHDVTVIE----CTGEPGGL------MARIANCRVGFKTFF---DEIRDKPRLTVIR- 66
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIEdegtCPYGGCVLskallgAAEAPEIASLWADLYkrkEEVVKKLNNGIEVl 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   67 -DARIAKVEKRENVFTV---ILEDGQSIRADRVIIAAGLSPYDPveykgkrvltsleydavidqrngDLPADFEKIGFFL 142
Cdd:pfam07992  81 lGTEVVSIDPGAKKVVLeelVDGDGETITYDRLVIATGARPRLP-----------------------PIPGVELNVGFLV 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  143 -----CVGSRSKEYPLCSSVC-CSYTLREVKWTLQRAKPEITVFYN---DLRFFGQEF--LMEKAYRDAGVRFvRANSRY 211
Cdd:pfam07992 138 rtldsAEALRLKLLPKRVVVVgGGYIGVELAAALAKLGKEVTLIEAldrLLRAFDEEIsaALEKALEKNGVEV-RLGTSV 216

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 655512805  212 FEEDDDGVTVRYFAAGGlKEERFNYAILAIGLRPNPELERLSGLFgfsRDEFGFAVEKEPLKADADGVYLAG 283
Cdd:pfam07992 217 KEIIGDGDGVEVILKDG-TEIDADLVVVAIGRRPNTELLEAAGLE---LDERGGIVVDEYLRTSVPGIYAAG 284
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 504-576 7.90e-14

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 66.29  E-value: 7.90e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 655512805 504 RILPEVSEDRCSGCGSCKEACPHDAIEMEMREQQValfgpnvvscapiahVKEGSCVGCGLCAATCPSHVISY 576
Cdd:COG1149    3 RKIPVIDEEKCIGCGLCVEVCPEGAIKLDDGGAPV---------------VDPDLCTGCGACVGVCPTGAITL 60
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 499-576 9.54e-13

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 65.50  E-value: 9.54e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 655512805 499 DVEEERILPEVSEDRCSGCGSCKEACPHDAIEMEMREQQVALFGPNVVscapiahVKEGSCVGCGLCAATCPSHVISY 576
Cdd:cd10549   27 PNGAIARGPEIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKEAE-------IDEEKCIGCGLCVKVCPVDAITL 97
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
506-575 7.69e-11

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 63.03  E-value: 7.69e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 655512805 506 LPEVSEDRCSGCGSCKEACPHDAIEMEMREQQValfgpnVVSCA---PIAHVK---EGSCVGCGLCAATCPSHVIS 575
Cdd:PRK07118 162 LPVVDEDKCTGCGACVKACPRNVIELIPKSARV------FVACNskdKGKAVKkvcEVGCIGCGKCVKACPAGAIT 231
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 514-571 1.82e-08

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 50.60  E-value: 1.82e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 655512805  514 CSGCGSCKEACPHDAIEMEMREQQVALFgpnvvscapIAHVKEGSCVGCGLCAATCPS 571
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKGTK---------TVVIDPERCVGCGACVAVCPT 49
PRK07233 PRK07233
hypothetical protein; Provisional
 2-41 2.72e-08

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 56.43  E-value: 2.72e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 655512805   2 NILVVGGGISGISAAKVALREGHDVTVIECTGEPGGLMAR 41
Cdd:PRK07233   1 KIAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGLAAS 40
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 499-575 1.71e-07

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 51.34  E-value: 1.71e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 655512805  499 DVEEERILPEVSEDRCSGCGSCKEACPHDAIememreqqvalfgpnvVSCAPIAH-VKEGSCVGCGLCAATCPSHVIS 575
Cdd:TIGR01944 100 GTIQPPMVALIDEDNCIGCTKCIQACPVDAI----------------VGAAKAMHtVIADECTGCDLCVEPCPTDCIE 161
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 5-105 1.51e-04

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 44.82  E-value: 1.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805    5 VVGGGISGISAAKVALREGHDVTVIECTgepGGLMARIANcRVGFKTFFDEIRDKPrLTVIRDARIAKVEKRENVFTVIL 84
Cdd:TIGR02374 145 VIGGGLLGLEAAVGLQNLGMDVSVIHHA---PGLMAKQLD-QTAGRLLQRELEQKG-LTFLLEKDTVEIVGATKADRIRF 219

                          90       100
                  ....*....|....*....|.
gi 655512805   85 EDGQSIRADRVIIAAGLSPYD 105
Cdd:TIGR02374 220 KDGSSLEADLIVMAAGIRPND 240
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 512-576 3.87e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 39.07  E-value: 3.87e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 655512805 512 DRCSGCGSCKEACPHDAIEMEMREqqvalfgpnvvscaPIAHvkeGSCVGCGLCAATCPSHVISY 576
Cdd:NF038196 185 DKCIGCGICAKVCPVNNIEMEDGK--------------PVWG---HNCTHCLACIHRCPKEAIEY 232
 
Name Accession Description Interval E-value
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
2-306 1.37e-62

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 215.88  E-value: 1.37e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   2 NILVVGGGISGISAAKVALREGHDVTVIECTGEPGGLMARIancrvgFKTF-------------FDEIRDKPRLTVIRDA 68
Cdd:COG1148  142 RALVIGGGIAGMTAALELAEQGYEVYLVEKEPELGGRAAQL------HKTFpgldcpqcileplIAEVEANPNITVYTGA 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  69 RIAKVEKRENVFTVILEDG----QSIRADRVIIAAGLSPYDPV---EY---KGKRVLTSLEYDAVIDQRNGDLPADF--- 135
Cdd:COG1148  216 EVEEVSGYVGNFTVTIKKGpreeIEIEVGAIVLATGFKPYDPTklgEYgygKYPNVITNLELERLLAAGKILRPSDGkep 295

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 136 EKIGFFLCVGSRSKEYPL--CSSVCCSYTLREVKWtLQRAKPE--ITVFYNDLRFFGQeflMEKAY---RDAGVRFVRAN 208
Cdd:COG1148  296 KSVAFIQCVGSRDEENGLpyCSRVCCMYALKQALY-LKEKNPDadVYIFYRDIRTYGK---YEEFYrraREDGVRFIRGR 371

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 209 -SRYFEEDDDGVTVRYF--AAGGLKEERFNYAILAIGLRPNPELERLSGLFGFSRDEFGFAVEKE----PLKADADGVYL 281
Cdd:COG1148  372 vAEIEEDEGGKLVVTVEdtLLGEPVEIEADLVVLATGMVPSEDNEELAKLLKLPLDQDGFFLEAHpklrPVETATDGIFL 451

                        330       340
                 ....*....|....*....|....*
gi 655512805 282 AGGSIEPMSIKDAILTGFGAAMRAV 306
Cdd:COG1148  452 AGAAHGPKDIPESIAQATAAAARAI 476
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 1-283 1.30e-14

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 74.66  E-value: 1.30e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805    1 MNILVVGGGISGISAAKVALREGHDVTVIE----CTGEPGGL------MARIANCRVGFKTFF---DEIRDKPRLTVIR- 66
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIEdegtCPYGGCVLskallgAAEAPEIASLWADLYkrkEEVVKKLNNGIEVl 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   67 -DARIAKVEKRENVFTV---ILEDGQSIRADRVIIAAGLSPYDPveykgkrvltsleydavidqrngDLPADFEKIGFFL 142
Cdd:pfam07992  81 lGTEVVSIDPGAKKVVLeelVDGDGETITYDRLVIATGARPRLP-----------------------PIPGVELNVGFLV 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  143 -----CVGSRSKEYPLCSSVC-CSYTLREVKWTLQRAKPEITVFYN---DLRFFGQEF--LMEKAYRDAGVRFvRANSRY 211
Cdd:pfam07992 138 rtldsAEALRLKLLPKRVVVVgGGYIGVELAAALAKLGKEVTLIEAldrLLRAFDEEIsaALEKALEKNGVEV-RLGTSV 216

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 655512805  212 FEEDDDGVTVRYFAAGGlKEERFNYAILAIGLRPNPELERLSGLFgfsRDEFGFAVEKEPLKADADGVYLAG 283
Cdd:pfam07992 217 KEIIGDGDGVEVILKDG-TEIDADLVVVAIGRRPNTELLEAAGLE---LDERGGIVVDEYLRTSVPGIYAAG 284
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 504-576 7.90e-14

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 66.29  E-value: 7.90e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 655512805 504 RILPEVSEDRCSGCGSCKEACPHDAIEMEMREQQValfgpnvvscapiahVKEGSCVGCGLCAATCPSHVISY 576
Cdd:COG1149    3 RKIPVIDEEKCIGCGLCVEVCPEGAIKLDDGGAPV---------------VDPDLCTGCGACVGVCPTGAITL 60
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
505-575 1.46e-13

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 65.91  E-value: 1.46e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 655512805 505 ILPEVSEDRCSGCGSCKEACPHDAIEMEMReqqvalfgpnvvscapIAHVKEGSCVGCGLCAATCPSHVIS 575
Cdd:COG2768    4 GKPYVDEEKCIGCGACVKVCPVGAISIEDG----------------KAVIDPEKCIGCGACIEVCPVGAIK 58
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 507-576 2.98e-13

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 64.69  E-value: 2.98e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 507 PEVSEDRCSGCGSCKEACPHDAIEMEmreqqvalfgpnvvscAPIAHVKEGSCVGCGLCAATCPSHVISY 576
Cdd:COG2221   10 PKIDEEKCIGCGLCVAVCPTGAISLD----------------DGKLVIDEEKCIGCGACIRVCPTGAIKG 63
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 511-575 7.48e-13

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 63.61  E-value: 7.48e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 655512805 511 EDRCSGCGSCKEACPHDAIEMEMREQqvalfgpnvvscAPIAHVKEGSCVGCGLCAATCPSHVIS 575
Cdd:COG1143    1 EDKCIGCGLCVRVCPVDAITIEDGEP------------GKVYVIDPDKCIGCGLCVEVCPTGAIS 53
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 499-576 9.54e-13

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 65.50  E-value: 9.54e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 655512805 499 DVEEERILPEVSEDRCSGCGSCKEACPHDAIEMEMREQQVALFGPNVVscapiahVKEGSCVGCGLCAATCPSHVISY 576
Cdd:cd10549   27 PNGAIARGPEIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKEAE-------IDEEKCIGCGLCVKVCPVDAITL 97
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 507-574 1.26e-12

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 65.11  E-value: 1.26e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 655512805 507 PEVSEDRCSGCGSCKEACPHDAIEMEmreqqvalfgpNVVSCAPIAHVKEGSCVGCGLCAATCPSHVI 574
Cdd:cd10549    1 LKYDPEKCIGCGICVKACPTDAIELG-----------PNGAIARGPEIDEDKCVFCGACVEVCPTGAI 57
NapF COG1145
Ferredoxin [Energy production and conversion];
491-576 3.74e-12

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 66.28  E-value: 3.74e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 491 GALGEILLDVEEERILPEVSEDRCSGCGSCKEACPHDAIEMEMREqqvalfgpnvvscaPIAHVKEGSCVGCGLCAATCP 570
Cdd:COG1145  161 GKKIEEELKIAIKKAKAVIDAEKCIGCGLCVKVCPTGAIRLKDGK--------------PQIVVDPDKCIGCGACVKVCP 226


                 ....*.
gi 655512805 571 SHVISY 576
Cdd:COG1145  227 VGAISL 232
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
3-308 1.50e-11

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 65.53  E-value: 1.50e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   3 ILVVGGGISGISAAKVALREGHDVTVIECtGEPGGLMA---RIANcrvgFKTFFDEIRDkPRL------------TVIRD 67
Cdd:COG0492    3 VVIIGAGPAGLTAAIYAARAGLKTLVIEG-GEPGGQLAttkEIEN----YPGFPEGISG-PELaerlreqaerfgAEILL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  68 ARIAKVEKRENVFTVILEDGQSIRADRVIIAAGLSP-YDPV----EYKGKRVLTSLEYDA--VIDQR-----NGDLPADf 135
Cdd:COG0492   77 EEVTSVDKDDGPFRVTTDDGTEYEAKAVIIATGAGPrKLGLpgeeEFEGRGVSYCATCDGffFRGKDvvvvgGGDSALE- 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 136 ekigfflcvgsrskeyplcssvccsytlrevkW--TLQRAKPEITVFYNDLRFFGQEFLMEKAYRDAGVRFVRaNSRYFE 213
Cdd:COG0492  156 --------------------------------EalYLTKFASKVTLIHRRDELRASKILVERLRANPKIEVLW-NTEVTE 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 214 -EDDD---GVTVRYFAAGGLKEERFNYAILAIGLRPNPELerLSGLfGFSRDEFGFAVEKEPLKADADGVYLAGGSIEPm 289
Cdd:COG0492  203 iEGDGrveGVTLKNVKTGEEKELEVDGVFVAIGLKPNTEL--LKGL-GLELDEDGYIVVDEDMETSVPGVFAAGDVRDY- 278

                        330
                 ....*....|....*....
gi 655512805 290 sIKDAILTGFGAAMRAVND 308
Cdd:COG0492  279 -KYRQAATAAGEGAIAALS 296
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 507-577 1.53e-11

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 59.72  E-value: 1.53e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 655512805 507 PEVSEDRCSGCGSCKEACPHDAIEMEmREQQVALfgpnvvscapiaHVKEGSCVGCGLCAATCPSHVISYP 577
Cdd:COG1146    3 PVIDTDKCIGCGACVEVCPVDVLELD-EEGKKAL------------VINPEECIGCGACELVCPVGAITVE 60
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 507-575 2.06e-11

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 60.07  E-value: 2.06e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 655512805 507 PEVSEDRCSGCGSCKEACPHDAIEMEMREQqvalfgpnvvscapiAHVKEGSCVGCGLCAATCPSHVIS 575
Cdd:COG1144   25 PVVDEDKCIGCGLCWIVCPDGAIRVDDGKY---------------YGIDYDYCKGCGICAEVCPVKAIE 78
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 508-576 5.79e-11

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 58.52  E-value: 5.79e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 655512805 508 EVSEDRCSGCGSCKEACPHDAIEMEMReqqvalfgpnvvscapIAHVKEGSCVGCGLCAATCPSHVISY 576
Cdd:COG4231   18 VIDEDKCTGCGACVKVCPADAIEEGDG----------------KAVIDPDLCIGCGSCVQVCPVDAIKL 70
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
2-103 7.03e-11

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 64.39  E-value: 7.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   2 NILVVGGGISGISAAKVALREGHDVTVIectgEPGG-LMARIANCRVGfkTFF-DEIRDKpRLTVIRDARIAKVEKRENV 79
Cdd:COG1251  144 RVVVIGGGLIGLEAAAALRKRGLEVTVV----ERAPrLLPRQLDEEAG--ALLqRLLEAL-GVEVRLGTGVTEIEGDDRV 216

                         90       100
                 ....*....|....*....|....
gi 655512805  80 FTVILEDGQSIRADRVIIAAGLSP 103
Cdd:COG1251  217 TGVRLADGEELPADLVVVAIGVRP 240
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
506-575 7.69e-11

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 63.03  E-value: 7.69e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 655512805 506 LPEVSEDRCSGCGSCKEACPHDAIEMEMREQQValfgpnVVSCA---PIAHVK---EGSCVGCGLCAATCPSHVIS 575
Cdd:PRK07118 162 LPVVDEDKCTGCGACVKACPRNVIELIPKSARV------FVACNskdKGKAVKkvcEVGCIGCGKCVKACPAGAIT 231
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 511-575 9.21e-11

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 62.32  E-value: 9.21e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 655512805 511 EDRCSGCGSCKEACPHDAIEMemreqqvalfGPNVvscapIAHVKEGSCVGCGLCAATCPSHVIS 575
Cdd:COG2878  136 EYGCIGCGDCIKACPFDAIVG----------AAKG-----MHTVDEDKCTGCGLCVEACPVDCIE 185
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 508-576 6.46e-10

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 57.02  E-value: 6.46e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 655512805 508 EVSEDRCSGCGSCKEACPHDAIEMEmreqqvalFGPNVVscapiahVKEGSCVGCGLCAATCPSHVISY 576
Cdd:cd10549   74 EIDEEKCIGCGLCVKVCPVDAITLE--------DELEIV-------IDKEKCIGCGICAEVCPVNAIKL 127
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
514-574 1.74e-09

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 59.18  E-value: 1.74e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 655512805 514 CSGCGSCKEACPHDAIEMEMReqqvalfgpnvvscapIAHVKEGSCVGCGLCAATCPSHVI 574
Cdd:PRK07118 141 CLGLGSCVAACPFDAIHIENG----------------LPVVDEDKCTGCGACVKACPRNVI 185
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 19-283 2.71e-09

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 58.67  E-value: 2.71e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  19 ALREGHDVTVIECTGEPGGlmariANCRvGFKTFFDEIRD-------------KPRLTVIRDARIAKVEKRENvfTVILE 85
Cdd:COG0446    1 RLGPDAEITVIEKGPHHSY-----QPCG-LPYYVGGGIKDpedllvrtpesfeRKGIDVRTGTEVTAIDPEAK--TVTLR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  86 DGQSIRADRVIIAAGLSP-YDPVE-YKGKRV--LTSLEY----DAVIDQRNGdlpadfEKIGFflcVGSrskeyplcssv 157
Cdd:COG0446   73 DGETLSYDKLVLATGARPrPPPIPgLDLPGVftLRTLDDadalREALKEFKG------KRAVV---IGG----------- 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 158 ccSYTLREVKWTLQRAKPEITVFYND---LRFFGQEF--LMEKAYRDAGVRFvransRYFE-----EDDDGVTVRyFAAG 227
Cdd:COG0446  133 --GPIGLELAEALRKRGLKVTLVERAprlLGVLDPEMaaLLEEELREHGVEL-----RLGEtvvaiDGDDKVAVT-LTDG 204

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 655512805 228 GlkEERFNYAILAIGLRPNPELERLSGLfgfSRDEFGFAVEKEPLKADADGVYLAG 283
Cdd:COG0446  205 E--EIPADLVVVAPGVRPNTELAKDAGL---ALGERGWIKVDETLQTSDPDVYAAG 255
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 3-283 4.12e-09

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 58.94  E-value: 4.12e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   3 ILVVGGGISGISAAKVALREGHDVTVIEcTGEPGG-----------LMARIANcrvgfktFFDEIRDKPRL--------- 62
Cdd:COG1249    6 LVVIGAGPGGYVAAIRAAQLGLKVALVE-KGRLGGtclnvgcipskALLHAAE-------VAHEARHAAEFgisagapsv 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  63 ---TVI--RDARIAKVE-------KRENV--------F----TVILEDGQSIRADRVIIAAGLSPYDP--VEYKGKRVLT 116
Cdd:COG1249   78 dwaALMarKDKVVDRLRggveellKKNGVdvirgrarFvdphTVEVTGGETLTADHIVIATGSRPRVPpiPGLDEVRVLT 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 117 SleyDAVIDQRngDLPadfEKIgffLCVGSrskeyplcssvccSYTLREVKWTLQRAKPEITVFYND---LRFFGQEF-- 191
Cdd:COG1249  158 S---DEALELE--ELP---KSL---VVIGG-------------GYIGLEFAQIFARLGSEVTLVERGdrlLPGEDPEIse 213

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 192 LMEKAYRDAGVRfVRANSRY--FEEDDDGVTVRYFAAGGLKEERFNYAILAIGLRPNPE---LERLsglfGFSRDEFGFA 266
Cdd:COG1249  214 ALEKALEKEGID-ILTGAKVtsVEKTGDGVTVTLEDGGGEEAVEADKVLVATGRRPNTDglgLEAA----GVELDERGGI 288

                        330
                 ....*....|....*..
gi 655512805 267 VEKEPLKADADGVYLAG 283
Cdd:COG1249  289 KVDEYLRTSVPGIYAIG 305
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 491-572 6.51e-09

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 54.95  E-value: 6.51e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 491 GALGEILLDVEEERI-LPEVSEDRC------SGCGSCKEACPHDAIEMEMREQqvaLFGPnvvscapiaHVKEGSCVGCG 563
Cdd:cd16373   69 GALRPLDLEEQKVKMgVAVIDKDRClawqggTDCGVCVEACPTEAIAIVLEDD---VLRP---------VVDEDKCVGCG 136


                 ....*....
gi 655512805 564 LCAATCPSH 572
Cdd:cd16373  137 LCEYVCPVE 145
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 3-115 7.96e-09

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 57.95  E-value: 7.96e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   3 ILVVGGGISGISAAKVALREGHDVTVIECTGEPGG---------LMARIAN--CRVGFKTFF---------DEIRD---- 58
Cdd:COG2072    9 VVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGtwrdnrypgLRLDTPShlYSLPFFPNWsddpdfptgDEILAylea 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  59 -----KPRLTVIRDARIAKVEKRE--NVFTVILEDGQSIRADRVIIAAGL--SPY---------------------DPVE 108
Cdd:COG2072   89 yadkfGLRRPIRFGTEVTSARWDEadGRWTVTTDDGETLTARFVVVATGPlsRPKipdipgledfageqlhsadwrNPVD 168


                 ....*..
gi 655512805 109 YKGKRVL 115
Cdd:COG2072  169 LAGKRVL 175
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 514-571 1.82e-08

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 50.60  E-value: 1.82e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 655512805  514 CSGCGSCKEACPHDAIEMEMREQQVALFgpnvvscapIAHVKEGSCVGCGLCAATCPS 571
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKGTK---------TVVIDPERCVGCGACVAVCPT 49
PRK07233 PRK07233
hypothetical protein; Provisional
 2-41 2.72e-08

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 56.43  E-value: 2.72e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 655512805   2 NILVVGGGISGISAAKVALREGHDVTVIECTGEPGGLMAR 41
Cdd:PRK07233   1 KIAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGLAAS 40
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 508-576 3.53e-08

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 52.39  E-value: 3.53e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 655512805 508 EVSEDRCSGCGSCKEACPHDAIEMEmreqqvalFGPNVVscapiahVKegsCVGCG---------LCAATCPSHVISY 576
Cdd:cd04410   76 LIDEDKCIGCGSCVEACPYGAIVFD--------PEPGKA-------VK---CDLCGdrldeglepACVKACPTGALTF 135
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 2-103 6.23e-08

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 54.82  E-value: 6.23e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   2 NILVVGGGISGISAAKVALREGHDVTVIECT----GEPGGLMARIancrvgfktFFDEIRDKpRLTVIRDARIAKVEKRE 77
Cdd:COG0446  126 RAVVIGGGPIGLELAEALRKRGLKVTLVERAprllGVLDPEMAAL---------LEEELREH-GVELRLGETVVAIDGDD 195

                         90       100
                 ....*....|....*....|....*.
gi 655512805  78 NVfTVILEDGQSIRADRVIIAAGLSP 103
Cdd:COG0446  196 KV-AVTLTDGEEIPADLVVVAPGVRP 220
Fer4_21 pfam14697
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 509-570 6.49e-08

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 434137 [Multi-domain]  Cd Length: 59  Bit Score: 49.20  E-value: 6.49e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 655512805  509 VSEDRCSGCGSCKEACP---HDAIEMEMREqqvalfgpnvvscapIAHVKEGSCVGCGLCAATCP 570
Cdd:pfam14697   3 IDEDTCIGCGKCYIACPdtsHQAIVGDGKR---------------HHTVIEDECTGCNLCVSVCP 52
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 517-575 1.07e-07

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 51.09  E-value: 1.07e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 655512805 517 CGSCKEACPHDAIEMEMREQQVALfgpnvvscaPiaHVKEGSCVGCGLCAATCPSHVIS 575
Cdd:cd10564   88 CRSCQDACPTQAIRFRPRLGGIAL---------P--ELDADACTGCGACVSVCPVGAIT 135
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 499-575 1.71e-07

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 51.34  E-value: 1.71e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 655512805  499 DVEEERILPEVSEDRCSGCGSCKEACPHDAIememreqqvalfgpnvVSCAPIAH-VKEGSCVGCGLCAATCPSHVIS 575
Cdd:TIGR01944 100 GTIQPPMVALIDEDNCIGCTKCIQACPVDAI----------------VGAAKAMHtVIADECTGCDLCVEPCPTDCIE 161
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 2-87 2.88e-07

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 48.35  E-value: 2.88e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805    2 NILVVGGGISGISAAKVALREGHDVTVIECTGEPGGLMARIANcrvgfKTFFDEIRDKpRLTVIRDARIAKVEKRENVFT 81
Cdd:pfam00070   1 RVVVVGGGYIGLELAGALARLGSKVTVVERRDRLLPGFDPEIA-----KILQEKLEKN-GIEFLLNTTVEAIEGNGDGVV 74


                  ....*.
gi 655512805   82 VILEDG 87
Cdd:pfam00070  75 VVLTDG 80
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 506-574 4.02e-07

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 51.53  E-value: 4.02e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 506 LPEVSEDRCSGCGSCKEACPHDAIEMEMREQQVAlfgpnVVSCAPIAHVKEGscVGC-GLCAATCPSHVI 574
Cdd:COG2878  161 MHTVDEDKCTGCGLCVEACPVDCIEMVPVSPTVV-----VSSWDKGKAVRKV--VGCiGLCCKKCCPAAA 223
PRK13795 PRK13795
hypothetical protein; Provisional
 481-570 4.38e-07

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 52.69  E-value: 4.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 481 GERWSRREFYGALGEILLDVEeeRILPEVSEdrCSGCGSCKEACPHDAIEMEmreqqvalfgpnvvSCAPIAHVKEGSCV 560
Cdd:PRK13795 554 GNIWARSEDKEAAASLFKDAA--RLLRRAAE--CVGCGVCVGACPTGAIRIE--------------EGKRKISVDEEKCI 615

                         90
                 ....*....|
gi 655512805 561 GCGLCAATCP 570
Cdd:PRK13795 616 HCGKCTEVCP 625
PRK08318 PRK08318
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;
504-570 5.33e-07

NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;


Pssm-ID: 236237 [Multi-domain]  Cd Length: 420  Bit Score: 52.25  E-value: 5.33e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 504 RILPEVSEDRCSGCGSCKEAC---PHDAIEMEMREqqvalfgpnvvscAPIAHVKEGSCVGCGLCAATCP 570
Cdd:PRK08318 334 IVYARIDQDKCIGCGRCYIACedtSHQAIEWDEDG-------------TRTPEVIEEECVGCNLCAHVCP 390
Fer4_16 pfam13484
4Fe-4S double cluster binding domain;
514-570 5.43e-07

4Fe-4S double cluster binding domain;


Pssm-ID: 463893 [Multi-domain]  Cd Length: 65  Bit Score: 47.10  E-value: 5.43e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 655512805  514 CSGCGSCKEACPHDAIEMEMREQQV------ALFGPNVVSCAPIAHVKEGSCVGCGLCAATCP 570
Cdd:pfam13484   1 CGSCGKCIDACPTGAIVGPEGVLDArrcisyLTIEKKGLIPDELRCLLGNRCYGCDICQDVCP 63
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 1-42 6.09e-07

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 52.14  E-value: 6.09e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 655512805   1 MNILVVGGGISGISAAKVALREGHDVTVIECTGEPGGLMARI 42
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGLIRTV 43
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 506-532 6.78e-07

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 48.78  E-value: 6.78e-07
                         10        20
                 ....*....|....*....|....*..
gi 655512805 506 LPEVSEDRCSGCGSCKEACPHDAIEME 532
Cdd:cd10564  111 LPELDADACTGCGACVSVCPVGAITLT 137
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 507-535 8.42e-07

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 46.64  E-value: 8.42e-07
                         10        20
                 ....*....|....*....|....*....
gi 655512805 507 PEVSEDRCSGCGSCKEACPHDAIEMEMRE 535
Cdd:COG1149   36 PVVDPDLCTGCGACVGVCPTGAITLEERE 64
FAD_oxidored pfam12831
FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases ...
 3-101 9.11e-07

FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases and related proteins.


Pssm-ID: 432816 [Multi-domain]  Cd Length: 420  Bit Score: 51.46  E-value: 9.11e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805    3 ILVVGGGISGISAAKVALREGHDVTVIECTGEPGGLM---------------------------ARIAN---------CR 46
Cdd:pfam12831   2 VVVVGGGPAGVAAAIAAARAGAKVLLVERRGFLGGMLtsglvgpdmgfylnkeqvvggiarefrQRLRArgglpgpygLR 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 655512805   47 VGFKTF--------FDEIRDKPRLTVIRDARIAKVEKREN-VFTVILED---GQSIRADRVIIAAGL 101
Cdd:pfam12831  82 GGWVPFdpevakavLDEMLAEAGVTVLLHTRVVGVVKEGGrITGVTVETkggRITIRAKVFIDATGD 148
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 496-532 1.03e-06

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 46.28  E-value: 1.03e-06
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 655512805 496 ILLDVEEERILPEVSEDRCSGCGSCKEACPHDAIEME 532
Cdd:COG1143   19 ITIEDGEPGKVYVIDPDKCIGCGLCVEVCPTGAISMT 55
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 511-570 1.07e-06

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 45.70  E-value: 1.07e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  511 EDRCSGCGSCKEACPHDAIEMEMREQQVALFGPNVVScapiahvkeGSCVGCGLCAATCP 570
Cdd:pfam13237   6 PDKCIGCGRCTAACPAGLTRVGAIVERLEGEAVRIGV---------WKCIGCGACVEACP 56
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 511-576 1.59e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 47.65  E-value: 1.59e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 655512805 511 EDRCSGCGSCKEACPHDAIEMEMREQqvalfgpnvvscAPIAhvkegsCVGCGLCAATCPSHVISY 576
Cdd:cd16370   82 KEKCIGCGNCVKACIVGAIFWDEETN------------KPII------CIHCGYCARYCPHDVLAM 129
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
511-576 2.08e-06

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 50.41  E-value: 2.08e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 655512805 511 EDRCSGCGSCKEACPHDAIEMEMREqqvalfgpnvvscAPIAHVKegsCVGCGLCAATCPSHVISY 576
Cdd:COG4624   90 KEKCKNCYPCVRACPVKAIKVDDGK-------------AEIDEEK---CISCGQCVAVCPFGAITE 139
fdxN_nitrog TIGR02936
ferredoxin III, nif-specific; Members of this family are homodimeric ferredoxins from nitrogen ...
 506-571 2.13e-06

ferredoxin III, nif-specific; Members of this family are homodimeric ferredoxins from nitrogen fixation regions of many nitrogen-fixing bacteria. As characterized in Rhodobacter capsulatus, these proteins are homodimeric, with two 4Fe-4S clusters bound per monomer. Although nif-specific, this protein family is not usiveral, as other nitrogenase systems may substitute flavodoxins, or different types of ferredoxin. [Central intermediary metabolism, Nitrogen fixation]


Pssm-ID: 274356 [Multi-domain]  Cd Length: 91  Bit Score: 46.25  E-value: 2.13e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 655512805  506 LPEVSEDRCSGCGSCKEACPHDAIEMEMREQQVALFGPNVVScAPIAH-----VKEGSCVGCGLCAATCPS 571
Cdd:TIGR02936  15 VTSIDQEKCIGCGRCYKVCGRDVLTLKGINEEGELVASDDDD-DEIERkvmvvANPGNCIGCGACARVCPK 84
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 507-574 2.14e-06

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 48.10  E-value: 2.14e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 655512805 507 PEVSEDRCSGCGSCKEACPHDAIEMEMREQQVALfgpnvvscapIAHVKEGSCVGCGLCAATCPSHVI 574
Cdd:PRK12387  33 PEYNPQQCIGCAACVNACPSNALTVETDLATGEL----------AWEFNLGRCIFCGRCEEVCPTAAI 90
Fer4_9 pfam13187
4Fe-4S dicluster domain;
513-574 2.15e-06

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 44.85  E-value: 2.15e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 655512805  513 RCSGCGSCKEACPHDAIeMEMREQQVAlfgpnvvscapIAHVKEGSCVGCGLCAATCPSHVI 574
Cdd:pfam13187   1 KCTGCGACVAACPAGAI-VPDLVGQTI-----------RGDIAGLACIGCGACVDACPRGAI 50
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 3-283 2.62e-06

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 50.18  E-value: 2.62e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   3 ILVVGGGISGISAAKVALREGHDVTVIEcTGEPGG------------------------------------------LMA 40
Cdd:PRK06292   6 VIVIGAGPAGYVAARRAAKLGKKVALIE-KGPLGGtclnvgcipskaliaaaeafheakhaeefgihadgpkidfkkVMA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  41 RIANCRVGFKTF-FDEIRDKPRLTVIRD-ARIAKvekrENVFTVileDGQSIRADRVIIAAG--LSPYDPVEY-KGKRVL 115
Cdd:PRK06292  85 RVRRERDRFVGGvVEGLEKKPKIDKIKGtARFVD----PNTVEV---NGERIEAKNIVIATGsrVPPIPGVWLiLGDRLL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 116 TSleyDAVIDQRngDLPADF----------EkIGFFLcvgSRskeypLCSSVccsyTLREVKWT-LQRAKPEITVFYNDL 184
Cdd:PRK06292 158 TS---DDAFELD--KLPKSLavigggviglE-LGQAL---SR-----LGVKV----TVFERGDRiLPLEDPEVSKQAQKI 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 185 rfFGQEFLMEKAYRDAGVrfvransryfEEDDDGVTVRYFAAGGLKEERFNYAILAIGLRPNPELERLSGLfGFSRDEFG 264
Cdd:PRK06292 220 --LSKEFKIKLGAKVTSV----------EKSGDEKVEELEKGGKTETIEADYVLVATGRRPNTDGLGLENT-GIELDERG 286

                        330
                 ....*....|....*....
gi 655512805 265 FAVEKEPLKADADGVYLAG 283
Cdd:PRK06292 287 RPVVDEHTQTSVPGIYAAG 305
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 498-535 2.82e-06

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 45.43  E-value: 2.82e-06
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 655512805 498 LDVEEERIlPEVSEDRCSGCGSCKEACPHDAIEMEMRE 535
Cdd:COG1144   47 IRVDDGKY-YGIDYDYCKGCGICAEVCPVKAIEMVPEE 83
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 511-575 3.28e-06

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 46.25  E-value: 3.28e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 655512805  511 EDRCSGCGSCKEACPHDAIEMEMREQQVALFGPNVVScapiahVKEGSCVGCGLCAATCPSHVIS 575
Cdd:TIGR01971  42 EEKCIGCTLCAAVCPADAIRVVPAEGEDGKRRLKFYE------INFGRCIFCGLCEEACPTDAIV 100
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
5-54 3.55e-06

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 44.83  E-value: 3.55e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 655512805    5 VVGGGISGISAAKVALREGHDVTVIECTGEPGGLMARIAN----CRVGFKTFFD 54
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYRVpgyvFDYGAHIFHG 54
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 508-575 4.18e-06

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 46.87  E-value: 4.18e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 655512805 508 EVSEDRCSGCGSCKEACPHDAIEMEMREQQVALFGPNVVSCApiahVKegscvgCGLCA---------ATCPSHVIS 575
Cdd:cd10554   81 QVDEERCIGCKLCVLACPFGAIEMAPTTVPGVDWERGPRAVA----VK------CDLCAgreggpacvEACPTKALT 147
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
507-576 4.57e-06

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 46.57  E-value: 4.57e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 655512805 507 PEVSEDRCSGCGSCKEACPHDAIEMEMREQQvalfgpnvvscaPIAHVkegsCVGCG------LCAATCPSHVISY 576
Cdd:COG1142   76 VVVDEEKCIGCGLCVLACPFGAITMVGEKSR------------AVAVK----CDLCGgreggpACVEACPTGALRL 135
Fer4 pfam00037
4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...
 507-530 9.27e-06

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 459642 [Multi-domain]  Cd Length: 24  Bit Score: 42.24  E-value: 9.27e-06
                          10        20
                  ....*....|....*....|....
gi 655512805  507 PEVSEDRCSGCGSCKEACPHDAIE 530
Cdd:pfam00037   1 VVIDEEKCIGCGACVEVCPVGAIT 24
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
2-103 9.86e-06

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 47.60  E-value: 9.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805    2 NILVVGGGISGISAAKVALREGHDVTVIectGEPGGLMARIANCRVGFKT----FFDEIRDKPRLTVIRDARIAKVEKRE 77
Cdd:pfam13738 157 KVVVIGGYNSAVDAALELVRKGARVTVL---YRGSEWEDRDSDPSYSLSPdtlnRLEELVKNGKIKAHFNAEVKEITEVD 233

                          90       100
                  ....*....|....*....|....*..
gi 655512805   78 NVFTVILEDGQSIRA-DRVIIAAGLSP 103
Cdd:pfam13738 234 VSYKVHTEDGRKVTSnDDPILATGYHP 260
PRK05113 PRK05113
electron transport complex protein RnfB; Provisional
 498-575 9.87e-06

electron transport complex protein RnfB; Provisional


Pssm-ID: 235347 [Multi-domain]  Cd Length: 191  Bit Score: 46.48  E-value: 9.87e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 498 LDVEEERILPE-----VSEDRCSGCGSCKEACPHDAIememreqqvalfgpnvVSCAPIAH-VKEGSCVGCGLCAATCPS 571
Cdd:PRK05113  95 LDGEAQEATPArkvafIDEDNCIGCTKCIQACPVDAI----------------VGATKAMHtVISDLCTGCDLCVAPCPT 158


                 ....
gi 655512805 572 HVIS 575
Cdd:PRK05113 159 DCIE 162
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 509-575 1.22e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 45.02  E-value: 1.22e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 655512805 509 VSEDRCSGCGSCKEACPHDAieMEMREQQVALFgpnvvscapiahvkegSCVGCGLCAATCPSHVIS 575
Cdd:cd16372   74 INKKLCVGCLMCVGFCPEGA--MFKHEDYPEPF----------------KCIACGICVKACPTGALE 122
PRK06991 PRK06991
electron transport complex subunit RsxB;
500-570 1.35e-05

electron transport complex subunit RsxB;


Pssm-ID: 235903 [Multi-domain]  Cd Length: 270  Bit Score: 47.10  E-value: 1.35e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 655512805 500 VEEERILPEVSEDRCSGCGSCKEACPHDAIememreqqvalfgpnvVSCAPIAH-VKEGSCVGCGLCAATCP 570
Cdd:PRK06991  73 VERPRAVAVIDEQLCIGCTLCMQACPVDAI----------------VGAPKQMHtVLADLCTGCDLCVPPCP 128
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
514-574 2.18e-05

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 46.46  E-value: 2.18e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 655512805 514 CSGCGSCKEACPHDAIEMEmreqqvalfgPNVvscAPIAHVKegsCVGCGLCAATCPSHVI 574
Cdd:PRK07118 215 CIGCGKCVKACPAGAITME----------NNL---AVIDQEK---CTSCGKCVEKCPTKAI 259
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 511-576 2.32e-05

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 44.30  E-value: 2.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 511 EDRCSGCGSCKEAC--------PHDAIEMEMREQQVALFGPNVVSC-----AP----------------IAHVKEGSCVG 561
Cdd:cd04410    5 LDRCIGCGTCEVACkqehglrpGPDWSRIKVIEGGGLERAFLPVSCmhcedPPcvkacptgaiykdedgIVLIDEDKCIG 84

                         90
                 ....*....|....*
gi 655512805 562 CGLCAATCPSHVISY 576
Cdd:cd04410   85 CGSCVEACPYGAIVF 99
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 3-113 2.34e-05

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 47.15  E-value: 2.34e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   3 ILVVGGGISGISAAKVALREGHDVTVIECTGEPGGLMARIAncRVGFK---------------TFFDEIRDKPRLTVIRd 67
Cdd:COG1233    6 VVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTFE--RPGFRfdvgpsvltmpgvleRLFRELGLEDYLELVP- 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 655512805  68 ariakvekRENVFTVILEDGQSIR--ADRVIIAAGLSPYDPVEYKGKR 113
Cdd:COG1233   83 --------LDPAYRVPFPDGRALDlpRDLERTAAELERLFPGDAEAYR 122
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 509-576 2.49e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 44.10  E-value: 2.49e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 655512805 509 VSEDRCSGCGSCKEACPHDAIEMeMREQQVALfgpnvvscapiahvKEGSCVGCGLCAATCPSHVISY 576
Cdd:cd10550   77 VDEDKCIGCGMCVEACPFGAIRV-DPETGKAI--------------KCDLCGGDPACVKVCPTGALEF 129
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 3-103 2.79e-05

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 46.68  E-value: 2.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   3 ILVVGGGISGISAAKV--ALreGHDVTVIEctgepgGL----------MARIAncRVGFKtffdeirdKPRLTVIRDARI 70
Cdd:PRK06416 175 LVVIGGGYIGVEFASAyaSL--GAEVTIVE------ALprilpgedkeISKLA--ERALK--------KRGIKIKTGAKA 236

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 655512805  71 AKVEKRENVFTVILEDG---QSIRADRVIIAAGLSP 103
Cdd:PRK06416 237 KKVEQTDDGVTVTLEDGgkeETLEADYVLVAVGRRP 272
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 3-39 2.88e-05

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 47.03  E-value: 2.88e-05
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 655512805   3 ILVVGGGISGISAAKVALREGHDVTVIECTGEPGGLM 39
Cdd:PRK12814 196 VAIIGAGPAGLTAAYYLLRKGHDVTIFDANEQAGGMM 232
PRK08222 PRK08222
hydrogenase 4 subunit H; Validated
 507-574 2.90e-05

hydrogenase 4 subunit H; Validated


Pssm-ID: 181301 [Multi-domain]  Cd Length: 181  Bit Score: 45.13  E-value: 2.90e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 655512805 507 PEVSEDRCSGCGSCKEACPHDAIEMEMREQQVA----LFgpnvvscapiahvkEGSCVGCGLCAATCPSHVI 574
Cdd:PRK08222  33 PDLMPSQCIACGACTCACPANALTIQTDDQQNSrtwqLY--------------LGRCIYCGRCEEVCPTRAI 90
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 1-41 3.09e-05

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 46.77  E-value: 3.09e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 655512805   1 MNILVVGGGISGISAAkVALRE-GHDVTVIECTGEPGGLmAR 41
Cdd:COG3349    4 PRVVVVGGGLAGLAAA-VELAEaGFRVTLLEARPRLGGR-AR 43
psaC CHL00065
photosystem I subunit VII
 512-578 3.38e-05

photosystem I subunit VII


Pssm-ID: 177005 [Multi-domain]  Cd Length: 81  Bit Score: 42.44  E-value: 3.38e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 655512805 512 DRCSGCGSCKEACPHDAIEM----EMREQQVAlfgpnvvsCAPiahvKEGSCVGCGLCAATCPSHVISYPV 578
Cdd:CHL00065   9 DTCIGCTQCVRACPTDVLEMipwdGCKAKQIA--------SAP----RTEDCVGCKRCESACPTDFLSVRV 67
Fer4_8 pfam13183
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 513-573 3.58e-05

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 433017 [Multi-domain]  Cd Length: 64  Bit Score: 41.91  E-value: 3.58e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 655512805  513 RCSGCGSCKEACP-------HDAIEMEMREQQVALFGPNVVSCAPIAHvkegSCVGCGLCAATCPSHV 573
Cdd:pfam13183   1 RCIRCGACLAACPvylvtggRFPGDPRGGAAALLGRLEALEGLAEGLW----LCTLCGACTEVCPVGI 64
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
1-30 3.75e-05

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 46.05  E-value: 3.75e-05
                         10        20        30
                 ....*....|....*....|....*....|
gi 655512805   1 MNILVVGGGISGISAAKVALREGHDVTVIE 30
Cdd:COG0665    3 ADVVVIGGGIAGLSTAYHLARRGLDVTVLE 32
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 508-532 4.23e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 41.95  E-value: 4.23e-05
                         10        20
                 ....*....|....*....|....*
gi 655512805 508 EVSEDRCSGCGSCKEACPHDAIEME 532
Cdd:COG4231   47 VIDPDLCIGCGSCVQVCPVDAIKLE 71
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
520-575 4.28e-05

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 43.49  E-value: 4.28e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 655512805 520 CKEACPHDAIEMEmreqqvalfgPNVVscapiaHVKEGSCVGCGLCAATCPSHVIS 575
Cdd:COG1142   60 CAEVCPVGAITRD----------DGAV------VVDEEKCIGCGLCVLACPFGAIT 99
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 513-575 5.21e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 43.78  E-value: 5.21e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 655512805 513 RCSGCGSCKEACPHDAIEMEMREQQVALFGpnvvscAPIAHVKEGSCVGCG-LCAATCPSHVIS 575
Cdd:cd16373   15 LCIRCGLCVEACPTGVIQPAGLEDGLEGGR------TPYLDPREGPCDLCCdACVEVCPTGALR 72
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-99 7.80e-05

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 44.93  E-value: 7.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   1 MNILVVGGGISGISAAkVAL-REGHDVTVIE-------------------------------------------CTGEPG 36
Cdd:COG0654    4 TDVLIVGGGPAGLALA-LALaRAGIRVTVVErappprpdgrgialsprslellrrlglwdrllargapirgirvRDGSDG 82

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 655512805  37 GLMARIANCRVGFKTFF----DEIRD-------KPRLTVIRDARIAKVEKRENVFTVILEDGQSIRADrVIIAA 99
Cdd:COG0654   83 RVLARFDAAETGLPAGLvvprADLERalleaarALGVELRFGTEVTGLEQDADGVTVTLADGRTLRAD-LVVGA 155
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 3-37 8.41e-05

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 45.08  E-value: 8.41e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 655512805    3 ILVVGGGISGISAAKVALREGHDVTVIECTGEPGG 37
Cdd:pfam01266   2 VVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGS 36
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 475-574 8.64e-05

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 45.25  E-value: 8.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 475 FIRYPRGERwSRREFYGALG---EILLDVEEERILPEVSedRCSGCGSCKE------ACPHDAIEMEMREQQValfgpnv 545
Cdd:PRK12771 467 FTDAPRAQR-PELDADERVGdfdEVLGGLTEEEARQEAA--RCLSCGNCFEcdncygACPQDAIIKLGPGRRY------- 536

                         90       100
                 ....*....|....*....|....*....
gi 655512805 546 vscapiaHVKEGSCVGCGLCAATCPSHVI 574
Cdd:PRK12771 537 -------HFDYDKCTGCHICADVCPCGAI 558
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
1-108 1.06e-04

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 44.74  E-value: 1.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   1 MNILVVGGGISGISAAKV---ALREGHDVTVIECT----------GEPGGLMARiANCRVGFKTFFdeirDKPRLTVIRD 67
Cdd:COG1252    2 KRIVIVGGGFAGLEAARRlrkKLGGDAEVTLIDPNpyhlfqpllpEVAAGTLSP-DDIAIPLRELL----RRAGVRFIQG 76

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 655512805  68 aRIAKVEKRENvfTVILEDGQSIRADRVIIAAGLSP-YDPVE 108
Cdd:COG1252   77 -EVTGIDPEAR--TVTLADGRTLSYDYLVIATGSVTnFFGIP 115
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 502-532 1.08e-04

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 42.38  E-value: 1.08e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 655512805 502 EERILPEVSEDRCSGCGSCKEACPHDAIEME 532
Cdd:cd10549   98 EDELEIVIDKEKCIGCGICAEVCPVNAIKLV 128
FrhG TIGR03294
coenzyme F420 hydrogenase, subunit gamma; This model represents that clade of F420-dependent ...
 509-570 1.18e-04

coenzyme F420 hydrogenase, subunit gamma; This model represents that clade of F420-dependent hydrogenases (FRH) beta subunits found exclusively and universally in methanogenic archaea. This protein contains two 4Fe-4S cluster binding domains (pfam00037) and scores above the trusted cutoff to model pfam01058 for the "NADH ubiquinone oxidoreductase, 20 Kd subunit" family.


Pssm-ID: 132337 [Multi-domain]  Cd Length: 228  Bit Score: 43.69  E-value: 1.18e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 655512805  509 VSEDRCSGCGSCKEACPHDAIEMEMREqqvalfgPNvvscapiahVKEGSCVGCGLCAATCP 570
Cdd:TIGR03294 171 VNQGLCMGCGTCAAACPTRAIEMEDGR-------PN---------VNRDRCIKCGACYVQCP 216
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 3-39 1.21e-04

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 44.87  E-value: 1.21e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 655512805   3 ILVVGGGISGISAAKVALREGHDVTVIECTGEPGGLM 39
Cdd:PRK12771 140 VAVIGGGPAGLSAAYHLRRMGHAVTIFEAGPKLGGMM 176
NapF COG1145
Ferredoxin [Energy production and conversion];
498-537 1.22e-04

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 43.94  E-value: 1.22e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 655512805 498 LDVEEERILPEVSEDRCSGCGSCKEACPHDAIEMEMREQQ 537
Cdd:COG1145  199 IRLKDGKPQIVVDPDKCIGCGACVKVCPVGAISLEPKEIE 238
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
508-532 1.32e-04

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 40.48  E-value: 1.32e-04
                         10        20
                 ....*....|....*....|....*
gi 655512805 508 EVSEDRCSGCGSCKEACPHDAIEME 532
Cdd:COG2768   36 VIDPEKCIGCGACIEVCPVGAIKIE 60
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
1-37 1.49e-04

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 44.34  E-value: 1.49e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 655512805   1 MNILVVGGGISGISAAKVaLREGHDVTVIECTGEPGG 37
Cdd:COG2907    4 MRIAVIGSGISGLTAAWL-LSRRHDVTLFEANDRLGG 39
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 5-105 1.51e-04

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 44.82  E-value: 1.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805    5 VVGGGISGISAAKVALREGHDVTVIECTgepGGLMARIANcRVGFKTFFDEIRDKPrLTVIRDARIAKVEKRENVFTVIL 84
Cdd:TIGR02374 145 VIGGGLLGLEAAVGLQNLGMDVSVIHHA---PGLMAKQLD-QTAGRLLQRELEQKG-LTFLLEKDTVEIVGATKADRIRF 219

                          90       100
                  ....*....|....*....|.
gi 655512805   85 EDGQSIRADRVIIAAGLSPYD 105
Cdd:TIGR02374 220 KDGSSLEADLIVMAAGIRPND 240
oorD PRK09626
2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed
 509-574 1.54e-04

2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed


Pssm-ID: 236597 [Multi-domain]  Cd Length: 103  Bit Score: 41.24  E-value: 1.54e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 655512805 509 VSEDRCSGCGSCKEACPhdAIEMEMREQqvalfgPNVVSCAPIAHVKEGSCVGCGLCAATCPSHVI 574
Cdd:PRK09626  13 VDESRCKACDICVSVCP--AGVLAMRID------PHAVLGKMIKVVHPESCIGCRECELHCPDFAI 70
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 3-39 1.76e-04

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 44.36  E-value: 1.76e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 655512805   3 ILVVGGGISGISAAKVALREGHDVTVIECTGEPGGLM 39
Cdd:COG0493  124 VAVVGSGPAGLAAAYQLARAGHEVTVFEALDKPGGLL 160
PRK04965 PRK04965
NADH:flavorubredoxin reductase NorW;
3-103 1.82e-04

NADH:flavorubredoxin reductase NorW;


Pssm-ID: 179902 [Multi-domain]  Cd Length: 377  Bit Score: 44.14  E-value: 1.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   3 ILVVGGGISGISAAKVALREGHDVTVIECTGEP-GGLMARIANCRVGFktffdEIRDKPrLTVIRDARIAKVEKRENVFT 81
Cdd:PRK04965 144 VLVVGGGLIGTELAMDLCRAGKAVTLVDNAASLlASLMPPEVSSRLQH-----RLTEMG-VHLLLKSQLQGLEKTDSGIR 217

                         90       100
                 ....*....|....*....|..
gi 655512805  82 VILEDGQSIRADRVIIAAGLSP 103
Cdd:PRK04965 218 ATLDSGRSIEVDAVIAAAGLRP 239
PLN00071 PLN00071
photosystem I subunit VII; Provisional
 512-578 2.22e-04

photosystem I subunit VII; Provisional


Pssm-ID: 177700 [Multi-domain]  Cd Length: 81  Bit Score: 39.93  E-value: 2.22e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 655512805 512 DRCSGCGSCKEACPHDAIEMEMREQQVAlfgpNVVSCAPiahvKEGSCVGCGLCAATCPSHVISYPV 578
Cdd:PLN00071   9 DTCIGCTQCVRACPTDVLEMIPWDGCKA----KQIASAP----RTEDCVGCKRCESACPTDFLSVRV 67
Fer4_17 pfam13534
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 513-573 2.76e-04

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 433287 [Multi-domain]  Cd Length: 61  Bit Score: 39.37  E-value: 2.76e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 655512805  513 RCSGCGSCKEACP-HDAIEME----MREQQVALFGPnvvscAPIAHVKEgSCVGCGLCAATCPSHV 573
Cdd:pfam13534   1 RCIQCGCCVDECPrYLLNGDEpkklMRAAYLGDLEE-----LQANKVAN-LCSECGLCEYACPMGL 60
PRK06273 PRK06273
ferredoxin; Provisional
 489-532 2.78e-04

ferredoxin; Provisional


Pssm-ID: 235764 [Multi-domain]  Cd Length: 165  Bit Score: 41.62  E-value: 2.78e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 655512805 489 FYGALGEILL------DVE-EERIL-------PEVSEDRCSGCGSCKEACPHDAIEME 532
Cdd:PRK06273  12 IYENLERIIFgsdrytDKEmRNAILtgtvelpKKVFEELCIGCGGCANVCPTKAIEMI 69
porD PRK09624
pyruvate ferredoxin oxidoreductase subunit delta; Reviewed
 506-574 2.81e-04

pyruvate ferredoxin oxidoreductase subunit delta; Reviewed


Pssm-ID: 170017 [Multi-domain]  Cd Length: 105  Bit Score: 40.40  E-value: 2.81e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 655512805 506 LPEVSEDRCSGCGSCKEACPHDAIEMEmrEQQVALFGPNVvscapiahvkegsCVGCGLCAATCPSHVI 574
Cdd:PRK09624  45 MPEFNRDKCVRCYLCYIYCPEPAIYLD--EEGYPVFDYDY-------------CKGCGICANECPTKAI 98
MurD COG0771
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ...
 1-29 2.90e-04

UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440534 [Multi-domain]  Cd Length: 445  Bit Score: 43.53  E-value: 2.90e-04
                         10        20
                 ....*....|....*....|....*....
gi 655512805   1 MNILVVGGGISGISAAKVALREGHDVTVI 29
Cdd:COG0771    5 KKVLVLGLGKSGLAAARLLAKLGAEVTVS 33
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 507-544 3.19e-04

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 43.62  E-value: 3.19e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 655512805 507 PEVSEDRCSGCGSCKEACPHDAIEM-----EMREQQVALFGPN 544
Cdd:COG1245   44 PVISEELCIGCGICVKKCPFDAISIvnlpeELEEDPVHRYGEN 86
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
3-241 3.80e-04

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 42.99  E-value: 3.80e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   3 ILVVGGGISGISAAKVALREGHDVTVIE------------------CTGEPGG--------LMARIANcRVGFKTfFDEI 56
Cdd:COG1231   10 VVIVGAGLAGLAAARELRKAGLDVTVLEardrvggrvwtlrfgddgLYAELGAmrippshtNLLALAR-ELGLPL-EPFP 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  57 RDKPRLTVIRDARIAKVEKRENVFTVILEDGQSIRADrviIAAGLSPYDPV--EYKGKRVLTSLEydavidqRNGDLPAD 134
Cdd:COG1231   88 NENGNALLYLGGKRVRAGEIAADLRGVAELLAKLLRA---LAAALDPWAHPaaELDRESLAEWLR-------RNGASPSA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 135 FEKIGFFL--CVGSRSKEYPLcssvccSYTLREVKWTLQRAkpeitvfyNDLRF---FGQefLMEKAYRDAG--VRF--- 204
Cdd:COG1231  158 RRLLGLLGagEYGADPDELSL------LDLLRYAASAGGGA--------QQFRIvggMDQ--LPRALAAELGdrIRLgap 221

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 655512805 205 VRAnsryFEEDDDGVTVRYfaaGGLKEERFNYAILAI 241
Cdd:COG1231  222 VTR----IRQDGDGVTVTT---DDGGTVRADAVIVTV 251
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 493-532 4.21e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 41.09  E-value: 4.21e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 655512805 493 LGEILLDVEEERILPEVSEDRCSGCGSCKEACPHD---AIEME 532
Cdd:cd16373  111 TEAIAIVLEDDVLRPVVDEDKCVGCGLCEYVCPVEppkAIVVE 153
ACS_1 cd01916
Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and ...
 501-573 4.75e-04

Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and methanogenic organisms and is responsible for the synthesis and breakdown of acetyl-CoA. ACS forms a heterotetramer with carbon monoxide dehydrogenase (CODH) consisting of two ACS and two CODH subunits. CODH reduces carbon dioxide to carbon monoxide and ACS then synthesizes acetyl-CoA from carbon monoxide, CoA, and a methyl group donated by another protein (CoFeSP). ACS has three structural domains, an N-terminal rossman fold domain with a helical region at its N-terminus which interacts with CODH, and two alpha + beta fold domains. A Ni-Fe-S center referred to as the A-cluster is located in the C-terminal domain. A large cavity exists between the three domains which may bind CoA.


Pssm-ID: 238897 [Multi-domain]  Cd Length: 731  Bit Score: 43.17  E-value: 4.75e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 655512805 501 EEERILPEVSE-----DRCSGCGSCKEACPHDAIEMEMREQqvALFGpnvvSCAPIAHVKEgSCVGCGLCAATCPSHV 573
Cdd:cd01916  349 KGEKKLPTDEEfqelaAKCTDCGWCTRACPNSLRIKEAMEA--AKEG----DFSGLADLFD-QCVGCGRCEQECPKEI 419
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 500-575 5.23e-04

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 39.54  E-value: 5.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  500 VEEERILPEVSED------RCSGCGSCKEACPHDAIEMEMREQqvalfgpnvvscaPIAHVKEGSCVGCGLCAATCPSHV 573
Cdd:TIGR00402  16 IEKTQIRPPWSAReslfsaVCTRCGECASACENNILQLGQQGQ-------------PTVEFDNAECDFCGKCAEACPTNA 82


                  ..
gi 655512805  574 IS 575
Cdd:TIGR00402  83 FH 84
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 496-576 8.33e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 39.87  E-value: 8.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 496 ILLDVEEERILPEVsedrCSGCG--SCKEACPHDAIEMEMREQQValfgpnvvscapiaHVKEGSCVGCGLCAATCPSHV 573
Cdd:cd10550   35 VVRFEPEGLDVPVV----CRQCEdaPCVEACPVGAISRDEETGAV--------------VVDEDKCIGCGMCVEACPFGA 96


                 ...
gi 655512805 574 ISY 576
Cdd:cd10550   97 IRV 99
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 512-575 8.52e-04

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 39.92  E-value: 8.52e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 655512805 512 DRCSGCGSCKEACPHDAIememrEQQVALFgpnvvscaPIAHVKEGSCVGCGLCAATCPSHVIS 575
Cdd:cd10564   13 DLCTRCGDCVEACPEGII-----VRGDGGF--------PELDFSRGECTFCGACAEACPEGALD 63
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
496-544 1.02e-03

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 42.10  E-value: 1.02e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 655512805 496 ILLDVEEERilPEVSEDRCSGCGSCKEACPHDAIE-----MEMREQQVALFGPN 544
Cdd:PRK13409  35 IEIDEDDGK--PVISEELCIGCGICVKKCPFDAISivnlpEELEEEPVHRYGVN 86
PRK08764 PRK08764
Rnf electron transport complex subunit RnfB;
503-574 1.04e-03

Rnf electron transport complex subunit RnfB;


Pssm-ID: 181550 [Multi-domain]  Cd Length: 135  Bit Score: 39.52  E-value: 1.04e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 655512805 503 ERILPEVS---EDRCSGCGSCKEACPHDAIEMEMREQQVALfgpnvvscAPIahvkegsCVGCGLCAATCPSHVI 574
Cdd:PRK08764  73 THKLPQVAwivEADCIGCTKCIQACPVDAIVGGAKHMHTVI--------APL-------CTGCELCVPACPVDCI 132
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
506-575 1.11e-03

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 38.77  E-value: 1.11e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 506 LPEVSEDRCSGCGSCKEACPHDAIEMEmREQQVAlfgpnvvscapiahVKEGSCVGCGLCAATCPSHVIS 575
Cdd:PRK09623  45 MPVVDESKCVKCYICWKFCPEPAIYIK-EDGYVA--------------IDYDYCKGCGICANECPTKAIT 99
PLN03000 PLN03000
amine oxidase
 2-37 1.28e-03

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 41.93  E-value: 1.28e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 655512805   2 NILVVGGGISGISAAKVALREGHDVTVIECTGEPGG 37
Cdd:PLN03000 186 SVVIVGAGLSGLAAARQLMRFGFKVTVLEGRKRPGG 221
PRK06753 PRK06753
hypothetical protein; Provisional
 1-30 1.30e-03

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 41.21  E-value: 1.30e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 655512805   1 MNILVVGGGISGISAAKVALREGHDVTVIE 30
Cdd:PRK06753   1 MKIAIIGAGIGGLTAAALLQEQGHEVKVFE 30
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 509-576 1.31e-03

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 39.59  E-value: 1.31e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 655512805 509 VSEDRCSGCGSCKEACPHDAIEMEMREQqvalfgpnvvscapiahvKEGSCVGC------GL---CAATCPSHVISY 576
Cdd:cd10562   97 VDEDKCIGCGYCVAACPFDVPRYDETTN------------------KITKCTLCfdrienGMqpaCVKTCPTGALTF 155
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 507-532 1.31e-03

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 37.34  E-value: 1.31e-03
                         10        20
                 ....*....|....*....|....*.
gi 655512805 507 PEVSEDRCSGCGSCKEACPHDAIEME 532
Cdd:COG2221   39 LVIDEEKCIGCGACIRVCPTGAIKGE 64
Fer4_6 pfam12837
4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to ...
 507-529 1.39e-03

4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 432822 [Multi-domain]  Cd Length: 24  Bit Score: 36.05  E-value: 1.39e-03
                          10        20
                  ....*....|....*....|...
gi 655512805  507 PEVSEDRCSGCGSCKEACPHDAI 529
Cdd:pfam12837   2 VEVDPDKCIGCGRCVVVCPYGAI 24
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 3-37 1.42e-03

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 41.49  E-value: 1.42e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 655512805    3 ILVVGGGISGISAAKVALREGHDVTVIECTGEPGG 37
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPGG 35
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 10-244 1.46e-03

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 41.32  E-value: 1.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   10 ISGISAAKVALREGHDVTVIECTGEPGGLMA--RIANCRV--GFKTFFDEirDKPRLTVIRDARIAKVEK---RENVFTV 82
Cdd:pfam01593   1 LAGLAAARELLRAGHDVTVLEARDRVGGRIRtvRDDGFLIelGAMWFHGA--QPPLLALLKELGLEDRLVlpdPAPFYTV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   83 ILEDGQSIRADRVIIAAG----LSPYDPVEYKGK----RVLTSLEYDAVIDQRNGDL-----------PADFEKIGFFLC 143
Cdd:pfam01593  79 LFAGGRRYPGDFRRVPAGweglLEFGRLLSIPEKlrlgLAALASDALDEFDLDDFSLaesllflgrrgPGDVEVWDRLID 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  144 VGSRSKeYPLCSSVCcsytlrEVKWTLQRAKPEITVFYNDLRFFGQEFL-----------MEKAYRDAGVRF---VRAns 209
Cdd:pfam01593 159 PELFAA-LPFASGAF------AGDPSELSAGLALPLLWALLGEGGSLLLprgglgalpdaLAAQLLGGDVRLntrVRS-- 229

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 655512805  210 ryFEEDDDGVTVRYFAAgglKEERFNYAILAIGLR 244
Cdd:pfam01593 230 --IDREGDGVTVTLTDG---EVIEADAVIVTVPLG 259
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 513-576 1.63e-03

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 39.59  E-value: 1.63e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 655512805 513 RCSGCG--SCKEACPHDAIememreqQVALFGpNVVscapiahVKEGSCVGCGLCAATCPSHVISY 576
Cdd:cd10562   69 QCMHCTdaACVKVCPTGAL-------YKTENG-AVV-------VDEDKCIGCGYCVAACPFDVPRY 119
flavo_MJ0208 TIGR02700
archaeoflavoprotein, MJ0208 family; This model describes one of two paralogous families of ...
 513-538 1.65e-03

archaeoflavoprotein, MJ0208 family; This model describes one of two paralogous families of archaealflavoprotein. The other, described by TIGR02699 and typified by the partially characterized AF1518 of Archaeoglobus fulgidus, is a homodimeric FMN-containing flavoprotein that accepts electrons from ferredoxin and can transfer them to various oxidoreductases. The function of this protein family is unknown. [Unknown function, General]


Pssm-ID: 131747 [Multi-domain]  Cd Length: 234  Bit Score: 40.24  E-value: 1.65e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 655512805  513 RCSGCGSCKEACPHDAI----EMEMREQQV 538
Cdd:TIGR02700 178 KCVGCGKCKEACPYNAIhgglEYEMRVRSV 207
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
3-117 1.74e-03

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 40.91  E-value: 1.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   3 ILVVGGGISGISAAKVALREGHDVTVIECTGEPGGlmariaNC-----------R------VGFKT--FFDEIRDKPRLT 63
Cdd:PRK05249   8 LVVIGSGPAGEGAAMQAAKLGKRVAVIERYRNVGG------GCthtgtipskalReavlrlIGFNQnpLYSSYRVKLRIT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  64 ---VIRDAR--IAK-VEKRENVFT--------------------VILEDG--QSIRADRVIIAAGLSPYDP--VEYKGKR 113
Cdd:PRK05249  82 fadLLARADhvINKqVEVRRGQYErnrvdliqgrarfvdphtveVECPDGevETLTADKIVIATGSRPYRPpdVDFDHPR 161


                 ....
gi 655512805 114 VLTS 117
Cdd:PRK05249 162 IYDS 165
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 5-39 1.77e-03

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 40.92  E-value: 1.77e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 655512805   5 VVGGGISGISAAKVALREGHDVTVIECTGEPGGLM 39
Cdd:PRK12810 148 VVGSGPAGLAAADQLARAGHKVTVFERADRIGGLL 182
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 1-30 1.90e-03

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 40.44  E-value: 1.90e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 655512805   1 MNILVVGGGISGISAAKVALREGHDVTVIE 30
Cdd:COG0569   96 MHVIIIGAGRVGRSLARELEEEGHDVVVID 125
SIMIBI_bact_arch cd03110
bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily ...
 498-575 2.12e-03

bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.


Pssm-ID: 349764 [Multi-domain]  Cd Length: 246  Bit Score: 40.06  E-value: 2.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 498 LDVEEERI---LPEVSEDRCSGCGSCKEACPHDAIememreqqvALFGPNVVscapiahVKEGSCVGCGLCAATCPSHVI 574
Cdd:cd03110   47 PEEEEDFVggkKAFIDQEKCIRCGNCERVCKFGAI---------LEFFQKLI-------VDESLCEGCGACVIICPRGAI 110


                 .
gi 655512805 575 S 575
Cdd:cd03110  111 Y 111
Fer4_6 pfam12837
4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to ...
 551-574 2.39e-03

4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 432822 [Multi-domain]  Cd Length: 24  Bit Score: 35.67  E-value: 2.39e-03
                          10        20
                  ....*....|....*....|....
gi 655512805  551 IAHVKEGSCVGCGLCAATCPSHVI 574
Cdd:pfam12837   1 VVEVDPDKCIGCGRCVVVCPYGAI 24
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 1-39 2.52e-03

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 40.60  E-value: 2.52e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 655512805   1 MNILVVGGGISGISAA----KvaLREGHDVTVIECTGEPGGLM 39
Cdd:PRK11883   1 KKVAIIGGGITGLSAAyrlhK--KGPDADITLLEASDRLGGKI 41
PRK08348 PRK08348
NADH-plastoquinone oxidoreductase subunit; Provisional
 512-575 2.77e-03

NADH-plastoquinone oxidoreductase subunit; Provisional


Pssm-ID: 181399 [Multi-domain]  Cd Length: 120  Bit Score: 37.89  E-value: 2.77e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 655512805 512 DRCSGCGSCKEACPHDAIEMEMREQQVALFgpnvvscapiahvkEGSCVGCGLCAATCPSHVIS 575
Cdd:PRK08348  42 DKCVGCRMCVTVCPAGVFVYLPEIRKVALW--------------TGRCVFCGQCVDVCPTGALQ 91
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 509-529 2.82e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 38.31  E-value: 2.82e-03
                         10        20
                 ....*....|....*....|.
gi 655512805 509 VSEDRCSGCGSCKEACPHDAI 529
Cdd:cd16371   81 VDQDKCIGCGYCVWACPYGAP 101
DMSOR_beta_like cd16367
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 511-532 3.05e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319889 [Multi-domain]  Cd Length: 138  Bit Score: 38.06  E-value: 3.05e-03
                         10        20
                 ....*....|....*....|..
gi 655512805 511 EDRCSGCGSCKEACPHDAIEME 532
Cdd:cd16367   85 SDACCGCGNCASACPYGAIQMV 106
RnfC COG4656
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and ...
 496-572 3.10e-03

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 443694 [Multi-domain]  Cd Length: 451  Bit Score: 40.12  E-value: 3.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 496 ILLDVEEeriLPEVSEDRCSGCGSCKEACP--------HDAIEMEMREQQVALfgpnvvscapiaHVKEgsCVGCGLCAA 567
Cdd:COG4656  351 LALTKEE---VPPPEEQPCIRCGRCVDACPmgllpqqlYWYARAGDFDKAEEY------------NLMD--CIECGCCSY 413


                 ....*
gi 655512805 568 TCPSH 572
Cdd:COG4656  414 VCPSK 418
PRK07845 PRK07845
flavoprotein disulfide reductase; Reviewed
 3-116 3.30e-03

flavoprotein disulfide reductase; Reviewed


Pssm-ID: 236112 [Multi-domain]  Cd Length: 466  Bit Score: 40.23  E-value: 3.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   3 ILVVGGGISGISAAKVALREGHDVTVIECTGePGGlMARIANCrVGFKTFF------DEIRDKPRLTVIRD------ARI 70
Cdd:PRK07845   4 IVIIGGGPGGYEAALVAAQLGADVTVIERDG-LGG-AAVLTDC-VPSKTLIataevrTELRRAAELGIRFIddgearVDL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805  71 AKVEKR------------------ENV------------------FTVILEDG--QSIRADRVIIAAGLSP--YDPVEYK 110
Cdd:PRK07845  81 PAVNARvkalaaaqsadirarlerEGVrviagrgrlidpglgphrVKVTTADGgeETLDADVVLIATGASPriLPTAEPD 160


                 ....*.
gi 655512805 111 GKRVLT 116
Cdd:PRK07845 161 GERILT 166
NAD_binding_9 pfam13454
FAD-NAD(P)-binding;
49-100 3.64e-03

FAD-NAD(P)-binding;


Pssm-ID: 433222 [Multi-domain]  Cd Length: 155  Bit Score: 38.41  E-value: 3.64e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 655512805   49 FKTFFDEIRDKPRLTVIRDaRIAKVEKRENVFTVILEDGQSIRADRVIIAAG 100
Cdd:pfam13454 103 FEEALARAPAGVTVRVHRA-RVTDLRPRGDGYRVLLADGRTLAADAVVLATG 153
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 512-576 3.87e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 39.07  E-value: 3.87e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 655512805 512 DRCSGCGSCKEACPHDAIEMEMREqqvalfgpnvvscaPIAHvkeGSCVGCGLCAATCPSHVISY 576
Cdd:NF038196 185 DKCIGCGICAKVCPVNNIEMEDGK--------------PVWG---HNCTHCLACIHRCPKEAIEY 232
PRK06847 PRK06847
hypothetical protein; Provisional
 2-30 3.91e-03

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 39.86  E-value: 3.91e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 655512805   2 NILVVGGGISGISAAkVALR-EGHDVTVIE 30
Cdd:PRK06847   6 KVLIVGGGIGGLSAA-IALRrAGIAVDLVE 34
PRK07121 PRK07121
FAD-binding protein;
3-37 4.56e-03

FAD-binding protein;


Pssm-ID: 180854 [Multi-domain]  Cd Length: 492  Bit Score: 39.87  E-value: 4.56e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 655512805   3 ILVVGGGISGISAAKVALREGHDVTVIECTGEPGG 37
Cdd:PRK07121  23 VVVVGFGAAGACAAIEAAAAGARVLVLERAAGAGG 57
GlpC COG0247
Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy ...
 492-539 4.66e-03

Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy production and conversion];


Pssm-ID: 440017 [Multi-domain]  Cd Length: 420  Bit Score: 39.68  E-value: 4.66e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 655512805 492 ALGEILLDVEEERILPEVSE--DRCSGCGSCKEACP----HDAIEMEMREQQVA 539
Cdd:COG0247  109 LLREVLEGELPLDLSEEVYEvlDLCLTCKACETACPsgvdIADLIAEARAQLVE 162
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 511-576 5.44e-03

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 38.39  E-value: 5.44e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 655512805 511 EDRCSGCGSCKEACPHDAIEMEmREQQVAlfgpnvvscapiahVKegsCVGCG---------LCAATCPSHVISY 576
Cdd:COG0437   89 YDKCIGCRYCVAACPYGAPRFN-PETGVV--------------EK---CTFCAdrldegllpACVEACPTGALVF 145
Fer4_9 pfam13187
4Fe-4S dicluster domain;
512-529 5.52e-03

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 35.22  E-value: 5.52e-03
                          10
                  ....*....|....*...
gi 655512805  512 DRCSGCGSCKEACPHDAI 529
Cdd:pfam13187  33 LACIGCGACVDACPRGAI 50
PRK00711 PRK00711
D-amino acid dehydrogenase;
1-36 6.13e-03

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 39.40  E-value: 6.13e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 655512805   1 MNILVVGGGISGISAAKVALREGHDVTVIECTGEPG 36
Cdd:PRK00711   1 MRVVVLGSGVIGVTSAWYLAQAGHEVTVIDRQPGPA 36
porD PRK09624
pyruvate ferredoxin oxidoreductase subunit delta; Reviewed
 502-535 6.73e-03

pyruvate ferredoxin oxidoreductase subunit delta; Reviewed


Pssm-ID: 170017 [Multi-domain]  Cd Length: 105  Bit Score: 36.55  E-value: 6.73e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 655512805 502 EERILPEVSEDRCSGCGSCKEACPHDAIEMeMRE 535
Cdd:PRK09624  71 DEEGYPVFDYDYCKGCGICANECPTKAIEM-VRE 103
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 2-30 7.37e-03

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 38.85  E-value: 7.37e-03
                         10        20
                 ....*....|....*....|....*....
gi 655512805   2 NILVVGGGISGISAAKVALREGHDVTVIE 30
Cdd:PRK12409   3 HIAVIGAGITGVTTAYALAQRGYQVTVFD 31
PRK06327 PRK06327
dihydrolipoamide dehydrogenase; Validated
 5-104 7.61e-03

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235779 [Multi-domain]  Cd Length: 475  Bit Score: 39.14  E-value: 7.61e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805   5 VVGGGISGISAAKVALREGHDVTVIEctGEPGGLMAriANCRVGfKTFFDEIrDKPRLTVIRDARIAKVEKRENVFTVIL 84
Cdd:PRK06327 188 VIGAGVIGLELGSVWRRLGAEVTILE--ALPAFLAA--ADEQVA-KEAAKAF-TKQGLDIHLGVKIGEIKTGGKGVSVAY 261

                         90       100
                 ....*....|....*....|....
gi 655512805  85 EDG----QSIRADRVIIAAGLSPY 104
Cdd:PRK06327 262 TDAdgeaQTLEVDKLIVSIGRVPN 285
FDH_beta_like cd16366
beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family ...
 509-576 7.77e-03

beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family contains beta FeS subunits of several dehydrogenases in the DMSO reductase superfamily, including formate dehydrogenase N (FDH-N), tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N is a major component of nitrate respiration of Escherichia coli; it catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate to a cytochrome. W-FDH contains a tungsten instead of molybdenum at the catalytic center and seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate.


Pssm-ID: 319888 [Multi-domain]  Cd Length: 156  Bit Score: 37.38  E-value: 7.77e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 655512805 509 VSEDRCSGCGSCKEACPHDAIEMEMREQQVAlfgpnvvscapiahvkegSCVGC------GL---CAATCPSHVISY 576
Cdd:cd16366   97 VDPETCIGCGYCVNACPFDIPRFDEETGRVA------------------KCTLCydrisnGLqpaCVKTCPTGALTF 155
PRK14993 PRK14993
tetrathionate reductase subunit TtrB;
513-570 8.14e-03

tetrathionate reductase subunit TtrB;


Pssm-ID: 184955 [Multi-domain]  Cd Length: 244  Bit Score: 38.32  E-value: 8.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 513 RCSGCGSCKEAC------PHDAIEMEMREQQVALFGPNVVS---------------CAPIAHV------KEG-------S 558
Cdd:PRK14993  52 RCIGCQSCTVSCtienqtPQGAFRTTVNQYQVQREGSQEVTnvllprlcnhcdnppCVPVCPVqatfqrEDGivvvdnkR 131

                         90
                 ....*....|..
gi 655512805 559 CVGCGLCAATCP 570
Cdd:PRK14993 132 CVGCAYCVQACP 143
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
486-576 9.64e-03

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 38.85  E-value: 9.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655512805 486 RREFYGALGEILLDVEEERILPEVSEDRCSGCGSCKEA-CPHDAIEMEMREQQVALFGPNVVSCaPIAHVKEGSCVGCGL 564
Cdd:COG4624   20 LLLEEAERVLRIIILEALLPEHVDDDSACSCCPRCCLCcCCCCRCCVAISCIQVRGIIIIDKRG-PSIIRDKEKCKNCYP 98

                         90
                 ....*....|..
gi 655512805 565 CAATCPSHVISY 576
Cdd:COG4624   99 CVRACPVKAIKV 110
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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