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Conserved domains on  [gi|658531754|ref|WP_029726001|]
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MULTISPECIES: glycosyltransferase [Bacillus]

Protein Classification

glycosyltransferase( domain architecture ID 1007466)

glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds

EC:  2.4.-.-
Gene Ontology:  GO:0016757|GO:0006486
PubMed:  16037492|12691742|10521532
SCOP:  3001586

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glycosyltransferase_GTB-type super family cl10013
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 209-498 1.52e-61

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


The actual alignment was detected with superfamily member cd04949:

Pssm-ID: 471961 [Multi-domain]  Cd Length: 328  Bit Score: 204.46  E-value: 1.52e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 209 FKNKHQFHTHWLETLCEKEKDpIIICDGVGSASKVNEMRAGLAKRFYCVHSNHLDYPYTLG-SKVRTNHQYAMEHIKDYD 287
Cdd:cd04949   37 FLNEQELFAFFIEQLNLQKGD-IFISDRPTLTGQVILNTKGPAKKGAVLHNEHVKNNDDPEhSLIKNFYKYVFENLNKYD 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 288 GLIVLTNEQKEDIMKDFESNNNIFVIPHA--PRRLEKLQTYEKKKNEFVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLN 365
Cdd:cd04949  116 AIIVSTEQQKQDLSERFNKYPPIFTIPVGyvDQLDTAESNHERKSNKIITISRLAPEKQLDHLIEAVAKAVKKVPEITLD 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 366 IYGSGPGHEEYQQLIDDLKL-DNVHLKGYVANPAPFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKYSPRELIK 444
Cdd:cd04949  196 IYGYGEEREKLKKLIEELHLeDNVFLKGYHSNLDQEYQDAYLSLLTSQMEGFGLTLMEAIGHGLPVVSYDVKYGPSELIE 275

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 658531754 445 EHETGMLVEPDNIDMLAESIIYLYDNPERAIQYGKNAKNLMDtEYSEARLFERW 498
Cdd:cd04949  276 DGENGYLIEKNNIDALADKIIELLNDPEKLQQFSEESYKIAE-KYSTENVMEKW 328
Glyco_trans_A_1 super family cl37583
Glycosyl transferase 1 domain A; Glyco_trans_A_1 is family of found predominantly at the ...
 16-186 9.13e-05

Glycosyl transferase 1 domain A; Glyco_trans_A_1 is family of found predominantly at the N-terminus of various prokaryotic alpha-glucosyltransferases. According to whether the domain exists as a whole molecule or as a half molecule determines the number of sugar residues that the molecule transfers. Two-domain proteins are processive in that they transfer more than one sugar residue, processively; single domain proteins transfer just one sugar moiety.


The actual alignment was detected with superfamily member pfam09318:

Pssm-ID: 370428  Cd Length: 199  Bit Score: 43.49  E-value: 9.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754   16 GGITSSMMSRSFTFAERGHK-IDLVTLDYKDNYDQIEQVLKSAGRLHADV-NILNIYDDY-------KNQHKHiKIGEVQ 86
Cdd:pfam09318  12 GGLTKSLLLRAKLFGEECNInTFFLTFRFDLEFSQKIDEIFDKGIIDKKFtKIINLFDDFlipncngKEQYEE-RIGLDQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754   87 QSYYDQNrNRFEEPYAAYHNEEKLETEYFKNGlyikkkkwdESDNLLYVDHFNENMQMTKR-EFFQGGYVNKTVIFDTRS 165
Cdd:pfam09318  91 IKKHAGM-GKFAKTLLRLFDHEDNEMRMIRNE---------DGEQIEIVDYFHDKNQLEKReEYNKNGNLHKVSHFDQEL 160

                         170       180
                  ....*....|....*....|.
gi 658531754  166 GKINQIHYTAPDGFCYLTEWY 186
Cdd:pfam09318 161 GKMYLEEFINDNNHIYLDKGY 181
 
Name Accession Description Interval E-value
GT4_GtfA-like cd04949
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ...
 209-498 1.52e-61

accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340855 [Multi-domain]  Cd Length: 328  Bit Score: 204.46  E-value: 1.52e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 209 FKNKHQFHTHWLETLCEKEKDpIIICDGVGSASKVNEMRAGLAKRFYCVHSNHLDYPYTLG-SKVRTNHQYAMEHIKDYD 287
Cdd:cd04949   37 FLNEQELFAFFIEQLNLQKGD-IFISDRPTLTGQVILNTKGPAKKGAVLHNEHVKNNDDPEhSLIKNFYKYVFENLNKYD 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 288 GLIVLTNEQKEDIMKDFESNNNIFVIPHA--PRRLEKLQTYEKKKNEFVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLN 365
Cdd:cd04949  116 AIIVSTEQQKQDLSERFNKYPPIFTIPVGyvDQLDTAESNHERKSNKIITISRLAPEKQLDHLIEAVAKAVKKVPEITLD 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 366 IYGSGPGHEEYQQLIDDLKL-DNVHLKGYVANPAPFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKYSPRELIK 444
Cdd:cd04949  196 IYGYGEEREKLKKLIEELHLeDNVFLKGYHSNLDQEYQDAYLSLLTSQMEGFGLTLMEAIGHGLPVVSYDVKYGPSELIE 275

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 658531754 445 EHETGMLVEPDNIDMLAESIIYLYDNPERAIQYGKNAKNLMDtEYSEARLFERW 498
Cdd:cd04949  276 DGENGYLIEKNNIDALADKIIELLNDPEKLQQFSEESYKIAE-KYSTENVMEKW 328
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 329-483 2.35e-37

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 134.71  E-value: 2.35e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754  329 KKNEFVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPGHEEYQQLIDDLKL-DNVHLKGYVANPAP--FYQQAL 405
Cdd:pfam00534   1 KKKIILFVGRLEPEKGLDLLIKAFALLKEKNPNLKLVIAGDGEEEKRLKKLAEKLGLgDNVIFLGFVSDEDLpeLLKIAD 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 658531754  406 ATLLTSKFEGFSLAICESFSCATPVISFDVkYSPRELIKEHETGMLVEPDNIDMLAESIIYLYDNPERAIQYGKNAKN 483
Cdd:pfam00534  81 VFVLPSRYEGFGIVLLEAMACGLPVIASDV-GGPPEVVKDGETGFLVKPNNAEALAEAIDKLLEDEELRERLGENARK 157
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 400-503 1.36e-23

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 95.83  E-value: 1.36e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 400 FYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKySPRELIKEHETGMLVEPDNIDMLAESIIYLYDNPERAIQYGK 479
Cdd:COG0438   17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVG-GLPEVIEDGETGLLVPPGDPEALAEAILRLLEDPELRRRLGE 95

                         90       100
                 ....*....|....*....|....
gi 658531754 480 NAKNLMDTEYSEARLFERWEEVFE 503
Cdd:COG0438   96 AARERAEERFSWEAIAERLLALYE 119
PRK09922 PRK09922
lipopolysaccharide 1,6-galactosyltransferase;
216-465 2.13e-12

lipopolysaccharide 1,6-galactosyltransferase;


Pssm-ID: 182148 [Multi-domain]  Cd Length: 359  Bit Score: 68.58  E-value: 2.13e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 216 HTHWLETLCEKEKDPIIICDGVGSASKVNEMRAGLAKRFYCVHSNHLdypytlgsKVRTNHQYAMEHIKDYDGLIVLTNE 295
Cdd:PRK09922  72 HVYNFSKWLKETQPDIVICIDVISCLYANKARKKSGKQFKIFSWPHF--------SLDHKKHAECKKITCADYHLAISSG 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 296 QKEDIMKDFESNNNIFVI--PHAPRRLEKLQTYEKKKNEFVMVAR--YHEEKGIDKVIKAMGIVKKsrpDIVLNIYGSGP 371
Cdd:PRK09922 144 IKEQMMARGISAQRISVIynPVEIKTIIIPPPERDKPAVFLYVGRlkFEGQKNVKELFDGLSQTTG---EWQLHIIGDGS 220

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 372 GHEEYQQLIDDLKLD-NVHLKGYVANPAPFYQQAL----ATLLTSKFEGFSLAICESFSCATPVISFDVKYSPRELIKEH 446
Cdd:PRK09922 221 DFEKCKAYSRELGIEqRIIWHGWQSQPWEVVQQKIknvsALLLTSKFEGFPMTLLEAMSYGIPCISSDCMSGPRDIIKPG 300

                        250
                 ....*....|....*....
gi 658531754 447 ETGMLVEPDNIDMLAESII 465
Cdd:PRK09922 301 LNGELYTPGNIDEFVGKLN 319
Glyco_trans_A_1 pfam09318
Glycosyl transferase 1 domain A; Glyco_trans_A_1 is family of found predominantly at the ...
 16-186 9.13e-05

Glycosyl transferase 1 domain A; Glyco_trans_A_1 is family of found predominantly at the N-terminus of various prokaryotic alpha-glucosyltransferases. According to whether the domain exists as a whole molecule or as a half molecule determines the number of sugar residues that the molecule transfers. Two-domain proteins are processive in that they transfer more than one sugar residue, processively; single domain proteins transfer just one sugar moiety.


Pssm-ID: 370428  Cd Length: 199  Bit Score: 43.49  E-value: 9.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754   16 GGITSSMMSRSFTFAERGHK-IDLVTLDYKDNYDQIEQVLKSAGRLHADV-NILNIYDDY-------KNQHKHiKIGEVQ 86
Cdd:pfam09318  12 GGLTKSLLLRAKLFGEECNInTFFLTFRFDLEFSQKIDEIFDKGIIDKKFtKIINLFDDFlipncngKEQYEE-RIGLDQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754   87 QSYYDQNrNRFEEPYAAYHNEEKLETEYFKNGlyikkkkwdESDNLLYVDHFNENMQMTKR-EFFQGGYVNKTVIFDTRS 165
Cdd:pfam09318  91 IKKHAGM-GKFAKTLLRLFDHEDNEMRMIRNE---------DGEQIEIVDYFHDKNQLEKReEYNKNGNLHKVSHFDQEL 160

                         170       180
                  ....*....|....*....|.
gi 658531754  166 GKINQIHYTAPDGFCYLTEWY 186
Cdd:pfam09318 161 GKMYLEEFINDNNHIYLDKGY 181
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 343-502 1.71e-04

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 44.15  E-value: 1.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 343 KGIDKVIKAMGIVKKSRPD----IVlniygsGPGHE--EYQQ----LIDDLKL-DNVHLKGY--VANPAPfyqQALATLL 409
Cdd:NF038011 319 KDIKTFIRAMRTVVRAMPEaegwIV------GPEEEdpAYAAecrsLVASLGLqDKVKFLGFqkIDDLLP---QVGLMVL 389

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 410 TSKFEGFSLAICESFSCATPVISFDVKySPRELIKEHET--------GMLVEPDNIDMLAESIIYLYDNPER--AIQygk 479
Cdd:NF038011 390 SSISEALPLVVLEAFAAGVPVVTTDVG-SCRQLIEGLDEedralgaaGEVVAIADPQALARAALDLLRDPQRwqAAQ--- 465

                        170       180
                 ....*....|....*....|....*
gi 658531754 480 nAKNLMDTE--YSEARLFERWEEVF 502
Cdd:NF038011 466 -AAGLARVEryYTEELMFDRYRELY 489
 
Name Accession Description Interval E-value
GT4_GtfA-like cd04949
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ...
 209-498 1.52e-61

accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340855 [Multi-domain]  Cd Length: 328  Bit Score: 204.46  E-value: 1.52e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 209 FKNKHQFHTHWLETLCEKEKDpIIICDGVGSASKVNEMRAGLAKRFYCVHSNHLDYPYTLG-SKVRTNHQYAMEHIKDYD 287
Cdd:cd04949   37 FLNEQELFAFFIEQLNLQKGD-IFISDRPTLTGQVILNTKGPAKKGAVLHNEHVKNNDDPEhSLIKNFYKYVFENLNKYD 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 288 GLIVLTNEQKEDIMKDFESNNNIFVIPHA--PRRLEKLQTYEKKKNEFVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLN 365
Cdd:cd04949  116 AIIVSTEQQKQDLSERFNKYPPIFTIPVGyvDQLDTAESNHERKSNKIITISRLAPEKQLDHLIEAVAKAVKKVPEITLD 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 366 IYGSGPGHEEYQQLIDDLKL-DNVHLKGYVANPAPFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKYSPRELIK 444
Cdd:cd04949  196 IYGYGEEREKLKKLIEELHLeDNVFLKGYHSNLDQEYQDAYLSLLTSQMEGFGLTLMEAIGHGLPVVSYDVKYGPSELIE 275

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 658531754 445 EHETGMLVEPDNIDMLAESIIYLYDNPERAIQYGKNAKNLMDtEYSEARLFERW 498
Cdd:cd04949  276 DGENGYLIEKNNIDALADKIIELLNDPEKLQQFSEESYKIAE-KYSTENVMEKW 328
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 251-500 3.20e-52

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 180.51  E-value: 3.20e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 251 AKRFYCVHSNHLDYPYTLGSKVRTNHQYamehiKDYDGLIVLTneqKEDIMKDFE-SNNNIFVIPHAPRRLEKLQTYEKK 329
Cdd:cd03820  109 SKLIVWEHNNYEAYNKGLRRLLLRRLLY-----KRADKIVVLT---EADKLKKYKqPNSNVVVIPNPLSFPSEEPSTNLK 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 330 KNEFVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPGHEEYQQLIDDLKL-DNVHLKGYVANPAPFYQQALATL 408
Cdd:cd03820  181 SKRILAVGRLTYQKGFDLLIEAWALIAKKHPDWKLRIYGDGPEREELEKLIDKLGLeDRVKLLGPTKNIAEEYANSSIFV 260

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 409 LTSKFEGFSLAICESFSCATPVISFDVKYSPRELIKEHETGMLVEPDNIDMLAESIIYLYDNPERAIQYGKNAKNLMDtE 488
Cdd:cd03820  261 LSSRYEGFPMVLLEAMAYGLPIISFDCPTGPSEIIEDGENGLLVPNGDVDALAEALLRLMEDEELRKKMGKNARKNAE-R 339

                        250
                 ....*....|..
gi 658531754 489 YSEARLFERWEE 500
Cdd:cd03820  340 FSIEKIIKQWEE 351
GT4_GT28_WabH-like cd03811
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ...
 231-483 7.62e-40

family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.


Pssm-ID: 340839 [Multi-domain]  Cd Length: 351  Bit Score: 147.50  E-value: 7.62e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 231 IIICDGVGSASKVNEMRAGLAKRFYCVHsNHLDYPYTLGSKVRTNHQYamehIKDYDGLIVLTNEQKEDIMKDFESN-NN 309
Cdd:cd03811   86 VVISFLGFATYIVAKLAAARSKVIAWIH-SSLSKLYYLKKKLLLKLKL----YKKADKIVCVSKGIKEDLIRLGPSPpEK 160

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 310 IFVIP-------HAPRRLEKLQTYEKKKNEFVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPGHEEYQQLIDD 382
Cdd:cd03811  161 IEVIYnpididrIRALAKEPILNEPEDGPVILAVGRLDPQKGHDLLIEAFAKLRKKYPDVKLVILGDGPLREELEKLAKE 240

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 383 LKL-DNVHLKGYVANPAPFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKYsPRELIKEHETGMLVEPDNIDMLA 461
Cdd:cd03811  241 LGLaERVIFLGFQSNPYPYLKKADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCPG-PREILDDGENGLLVPDGDAAALA 319

                        250       260
                 ....*....|....*....|..
gi 658531754 462 ESIIYLYDNPERAIQYGKNAKN 483
Cdd:cd03811  320 GILAALLQKKLDAALRERLAKA 341
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 231-503 2.29e-39

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 146.53  E-value: 2.29e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 231 IIICDGVGSASKVNEMRAGLAKRF-YCVHSNHLDYPYTLGSKVRTNHQYAMEHIKDYDGLIVLTNEQKEDIMKDF-ESNN 308
Cdd:cd03801   85 VVHAHGLLAALLAALLALLLGAPLvVTLHGAEPGRLLLLLAAERRLLARAEALLRRADAVIAVSEALRDELRALGgIPPE 164

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 309 NIFVIPHA------PRRLEKLQTYEKKKNEFVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGS-GPGHEEYQQLID 381
Cdd:cd03801  165 KIVVIPNGvdlerfSPPLRRKLGIPPDRPVLLFVGRLSPRKGVDLLLEALAKLLRRGPDVRLVIVGGdGPLRAELEELEL 244

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 382 DLKlDNVHLKGYVANP--APFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVkYSPRELIKEHETGMLVEPDNIDM 459
Cdd:cd03801  245 GLG-DRVRFLGFVPDEelPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDV-GGLPEVVEDGEGGLVVPPDDVEA 322

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 658531754 460 LAESIIYLYDNPERAIQYGKNAKNLMDTEYSEARLFERWEEVFE 503
Cdd:cd03801  323 LADALLRLLADPELRARLGRAARERVAERFSWERVAERLLDLYR 366
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 329-483 2.35e-37

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 134.71  E-value: 2.35e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754  329 KKNEFVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPGHEEYQQLIDDLKL-DNVHLKGYVANPAP--FYQQAL 405
Cdd:pfam00534   1 KKKIILFVGRLEPEKGLDLLIKAFALLKEKNPNLKLVIAGDGEEEKRLKKLAEKLGLgDNVIFLGFVSDEDLpeLLKIAD 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 658531754  406 ATLLTSKFEGFSLAICESFSCATPVISFDVkYSPRELIKEHETGMLVEPDNIDMLAESIIYLYDNPERAIQYGKNAKN 483
Cdd:pfam00534  81 VFVLPSRYEGFGIVLLEAMACGLPVIASDV-GGPPEVVKDGETGFLVKPNNAEALAEAIDKLLEDEELRERLGENARK 157
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 248-492 1.04e-35

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 136.19  E-value: 1.04e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 248 AGLAKRFYCVHSNH-LDYPYTLGSKVRTNhQYAMEHI--KDYDGLIVLTNEQKEDIMKD-FESNNNIFVIPHAPRRLE-- 321
Cdd:cd03808  100 ARLAGVPKVIYTVHgLGFVFTEGKLLRLL-YLLLEKLalLFTDKVIFVNEDDRDLAIKKgIIKKKKTVLIPGSGVDLDrf 178

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 322 --KLQTYEKKKNEFVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPGHEEYQQLIDDLKL-DNVHLKGYVANPA 398
Cdd:cd03808  179 qySPESLPSEKVVFLFVARLLKDKGIDELIEAAKILKKKGPNVRFLLVGDGELENPSEILIEKLGLeGRIEFLGFRSDVP 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 399 PFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKySPRELIKEHETGMLVEPDNIDMLAESIIYLYDNPERAIQYG 478
Cdd:cd03808  259 ELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVP-GCRELVIDGVNGFLVPPGDVEALADAIEKLIEDPELRKEMG 337

                        250
                 ....*....|....
gi 658531754 479 KNAKNLMDTEYSEA 492
Cdd:cd03808  338 EAARKRVEEKFDEE 351
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
333-470 1.31e-31

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 118.38  E-value: 1.31e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754  333 FVMVARYHEE-KGIDKVIKAMGIVKKSRPDIVLNIYGSGPgHEEYQQLIDDLKlDNVHLKGYVANPAPFYQQALATLLTS 411
Cdd:pfam13692   4 ILFVGRLHPNvKGVDYLLEAVPLLRKRDNDVRLVIVGDGP-EEELEELAAGLE-DRVIFTGFVEDLAELLAAADVFVLPS 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 658531754  412 KFEGFSLAICESFSCATPVISFDVKySPRELIkEHETGMLVEPDNIDMLAESIIYLYDN 470
Cdd:pfam13692  82 LYEGFGLKLLEAMAAGLPVVATDVG-GIPELV-DGENGLLVPPGDPEALAEAILRLLED 138
GT4_WbnK-like cd03807
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ...
 248-503 2.36e-25

Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.


Pssm-ID: 340836 [Multi-domain]  Cd Length: 362  Bit Score: 107.02  E-value: 2.36e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 248 AGLAKRFYCVHSNHLDYPytlgSKVRTNHQYAmeHIKDYDGLIVLT-NEQKEDIMKDFESNNNIFVI----------PHA 316
Cdd:cd03807  101 AGGVKVIWSVRSSNIPQR----LTRLVRKLCL--LLSKFSPATVANsSAVAEFHQEQGYAKNKIVVIyngidlfklsPDD 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 317 PRRLEKLQTYEKKKNEFVM--VARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPGHEEYQQLIDDLKL-DNVHLKGY 393
Cdd:cd03807  175 ASRARARRRLGLAEDRRVIgiVGRLHPVKDHSDLLRAAALLVETHPDLRLLLVGRGPERPNLERLLLELGLeDRVHLLGE 254

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 394 VANPAPFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKYSPrELIKEhETGMLVEPDNIDMLAESIIYLYDNPER 473
Cdd:cd03807  255 RSDVPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATDVGGAA-ELVDD-GTGFLVPAGDPQALADAIRALLEDPEK 332

                        250       260       270
                 ....*....|....*....|....*....|
gi 658531754 474 AIQYGKNAKNLMDTEYSEARLFERWEEVFE 503
Cdd:cd03807  333 RARLGRAARERIANEFSIDAMVRRYETLYY 362
GT4_WbuB-like cd03794
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ...
 287-499 1.96e-24

Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.


Pssm-ID: 340825 [Multi-domain]  Cd Length: 391  Bit Score: 105.12  E-value: 1.96e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 287 DGLIVLTNEQKEDIMKDFESNNNIFVIPH-------APRRLEKLQTYEKKKNEFVMV-ARYHEEK-GIDKVIKAMGIVKK 357
Cdd:cd03794  165 DAIIVLSPGLKEYLLRKGVPKEKIIVIPNwadleefKPPPKDELRKKLGLDDKFVVVyAGNIGKAqGLETLLEAAERLKR 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 358 sRPDIVLNIYGSGPGHEEYQQLIDDLKLDNVHLKGYV--ANPAPFYQQA---LATLLTSKFEGFSLA--ICESFSCATPV 430
Cdd:cd03794  245 -RPDIRFLFVGDGDEKERLKELAKARGLDNVTFLGRVpkEEVPELLSAAdvgLVPLKDNPANRGSSPskLFEYMAAGKPI 323

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 658531754 431 ISFDVKYSpRELIKEHETGMLVEPDNIDMLAESIIYLYDNPERAIQYGKNAKNLMDTEYSEARLFERWE 499
Cdd:cd03794  324 LASDDGGS-DLAVEINGCGLVVEPGDPEALADAILELLDDPELRRAMGENGRELAEEKFSREKLADRLL 391
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 400-503 1.36e-23

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 95.83  E-value: 1.36e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 400 FYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKySPRELIKEHETGMLVEPDNIDMLAESIIYLYDNPERAIQYGK 479
Cdd:COG0438   17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVG-GLPEVIEDGETGLLVPPGDPEALAEAILRLLEDPELRRRLGE 95

                         90       100
                 ....*....|....*....|....
gi 658531754 480 NAKNLMDTEYSEARLFERWEEVFE 503
Cdd:COG0438   96 AARERAEERFSWEAIAERLLALYE 119
GT4_UGDG-like cd03817
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ...
 256-483 1.13e-22

UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.


Pssm-ID: 340844 [Multi-domain]  Cd Length: 372  Bit Score: 99.66  E-value: 1.13e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 256 CVHSNHLDYP----YTLGSK---VRTNHQYAMEHIKDYDGLIVLTnEQKEDIMKDFESNNNIFVIPH--------APRRL 320
Cdd:cd03817  111 IVHTYHTMYEdylhYIPKGKllvKAVVRKLVRRFYNHTDAVIAPS-EKIKDTLREYGVKGPIEVIPNgidldkfeKPLNT 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 321 EKLQTYEKKKNEFV--MVARYHEEKGIDKVIKAMGIVKKsRPDIVLNIYGSGPGHEEYQQLIDDLKL-DNVHLKGYVAN- 396
Cdd:cd03817  190 EERRKLGLPPDEPIllYVGRLAKEKNIDFLLRAFAELKK-EPNIKLVIVGDGPEREELKELARELGLaDKVIFTGFVPRe 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 397 --PApFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKYSPrELIKEHETGMLVEPDNIdMLAESIIYLYDNPERA 474
Cdd:cd03817  269 elPE-YYKAADLFVFASTTETQGLVYLEAMAAGLPVVAAKDPAAS-ELVEDGENGFLFEPNDE-TLAEKLLHLRENLELL 345


                 ....*....
gi 658531754 475 IQYGKNAKN 483
Cdd:cd03817  346 RKLSKNAEI 354
GT4_MtfB-like cd03809
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ...
 251-500 3.73e-22

glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.


Pssm-ID: 340838 [Multi-domain]  Cd Length: 362  Bit Score: 97.82  E-value: 3.73e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 251 AKRFYCVH-SNHLDYPYTLGSKVRTNHQYAM-EHIKDYDGLIVLTNEQKEDIMKDF-ESNNNIFVIPHA-------PRRL 320
Cdd:cd03809  102 CPQVVTIHdLIPLRYPEFFPKRFRLYYRLLLpISLRRADAIITVSEATRDDIIKFYgVPPEKIVVIPLGvdpsffpPESA 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 321 EKLQTYEKKKNEFV-MVARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGS-GPGHEEYQQLIDDLKL-DNVHLKGYVANP 397
Cdd:cd03809  182 AVLIAKYLLPEPYFlYVGTLEPRKNHERLLKAFALLKKQGGDLKLVIVGGkGWEDEELLDLVKKLGLgGRVRFLGYVSDE 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 398 --APFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVkYSPRELIKEHetGMLVEPDNIDMLAESIIYLYDNP---E 472
Cdd:cd03809  262 dlPALYRGARAFVFPSLYEGFGLPVLEAMACGTPVIASNI-SVLPEVAGDA--ALYFDPLDPESIADAILRLLEDPslrE 338

                        250       260
                 ....*....|....*....|....*....
gi 658531754 473 RAIQYG-KNAKNlmdteYSEARLFERWEE 500
Cdd:cd03809  339 ELIRKGlERAKK-----FSWEKTAEKTLE 362
GT4_WavL-like cd03819
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ...
 314-474 6.99e-20

Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.


Pssm-ID: 340846 [Multi-domain]  Cd Length: 345  Bit Score: 90.88  E-value: 6.99e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 314 PHAPRRLEKLQTYEKKKNEFV--MVARYHEEKGIDKVIKAMGIVKKsRPDIVLNIYGSGPGHEEYQQLIDDLKLDN-VHL 390
Cdd:cd03819  164 FPPEAEAEERAQLGLPEGKPVvgYVGRLSPEKGWLLLVDAAAELKD-EPDFRLLVAGDGPERDEIRRLVERLGLRDrVTF 242

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 391 KGYVANPAPFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKySPRELIKEHETGMLVEPDNIDMLAESIIYLYDN 470
Cdd:cd03819  243 TGFREDVPAALAASDVVVLPSLHEEFGRVALEAMACGTPVVATDVG-GAREIVVHGRTGLLVPPGDAEALADAIRAAKLL 321


                 ....
gi 658531754 471 PERA 474
Cdd:cd03819  322 PEAR 325
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
 308-498 1.45e-19

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 90.52  E-value: 1.45e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 308 NNIFVIP---------HAPRRLEKlqtyEKKKNEFVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPGHEEYQQ 378
Cdd:cd03798  173 DRVDVIPngvdparfqPEDRGLGL----PLDAFVILFVGRLIPRKGIDLLLEAFARLAKARPDVVLLIVGDGPLREALRA 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 379 LIDDLKL-DNVHLKGYVANPA-PFYQQAL-ATLLTSKFEGFSLAICESFSCATPVISFDVKySPRELIKEHETGMLVEPD 455
Cdd:cd03798  249 LAEDLGLgDRVTFTGRLPHEQvPAYYRACdVFVLPSRHEGFGLVLLEAMACGLPVVATDVG-GIPEVVGDPETGLLVPPG 327

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 658531754 456 NIDMLAESII-YLYDNPERAiqygknaknlmDTEYSEARLFERW 498
Cdd:cd03798  328 DADALAAALRrALAEPYLRE-----------LGEAARARVAERF 360
GT4-like cd03813
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 308-503 3.01e-19

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340841 [Multi-domain]  Cd Length: 474  Bit Score: 90.47  E-value: 3.01e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 308 NNIFVIPHAPRRLEKlqtyeKKKNEFVM--VARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPGHEEY----QQLID 381
Cdd:cd03813  274 NGIDIQRFAPAREER-----PEKEPPVVglVGRVVPIKDVKTFIRAFKLVRRAMPDAEGWLIGPEDEDPEYaqecKRLVA 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 382 DLKL-DNVHLKGyVANPAPFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKySPRELI-----KEHETGMLVEPD 455
Cdd:cd03813  349 SLGLeNKVKFLG-FQNIKEYYPKLGLLVLTSISEGQPLVILEAMASGVPVVATDVG-SCRELIygaddALGQAGLVVPPA 426

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 658531754 456 NIDMLAESIIYLYDNPERAIQYGKNAKNLMDTEYSEARLFERWEEVFE 503
Cdd:cd03813  427 DPEALAEALIKLLRDPELRQAFGEAGRKRVEKYYTLEGMIDSYRKLYL 474
Glycosyltransferase_GTB-type cd01635
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 333-452 2.74e-17

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340816 [Multi-domain]  Cd Length: 235  Bit Score: 81.30  E-value: 2.74e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 333 FVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPGHEEYQQLIDDLKL--DNVHLKGYVANPAPFYQQALAT--L 408
Cdd:cd01635  113 KVSVGRLVPEKGIDLLLEALALLKARLPDLVLVLVGGGGEREEEEALAAALGLleRVVIIGGLVDDEVLELLLAAADvfV 192

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 658531754 409 LTSKFEGFSLAICESFSCATPVISFDVkYSPRELIKEHETGMLV 452
Cdd:cd01635  193 LPSRSEGFGLVLLEAMAAGKPVIATDV-GGIPEFVVDGENGLLV 235
GT4_WfcD-like cd03795
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ...
 328-493 3.28e-16

Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340826 [Multi-domain]  Cd Length: 355  Bit Score: 80.01  E-value: 3.28e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 328 KKKNEFVMVARYHEEKGIDKVIKAMGIVkksrpDIVLNIYGSGPGHEEYQQLIDDLKLDNVHLKGYVANP--APFYQQAL 405
Cdd:cd03795  189 KGKKIFLFIGRLVYYKGLDYLIEAAQYL-----NYPIVIGGEGPLKPDLEAQIELNLLDNVKFLGRVDDEekVIYLHLCD 263

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 406 ATLLTS--KFEGFSLAICESFSCATPVISFDVKYSPRELIKEHETGMLVEPDNIDMLAESIIYLYDNPERAIQYGKNAKN 483
Cdd:cd03795  264 VFVFPSvlRSEAFGIVLLEAMMCGKPVISTNIGTGVPYVNNNGETGLVVPPKDPDALAEAIDKLLSDEELRESYGENAKK 343

                        170
                 ....*....|
gi 658531754 484 LMDTEYSEAR 493
Cdd:cd03795  344 RFEELFTAEK 353
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
 306-503 1.63e-15

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 78.14  E-value: 1.63e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 306 SNNNIFVIPH-------APRRLEKLQ-TYEKKKNEFV--MVARYHEE--KGIDKVIKAM-GIVKKsrPDIVLNIYGSGPg 372
Cdd:cd03825  159 KGLPVVVIPNgidteifAPVDKAKARkRLGIPQDKKVilFGAESVTKprKGFDELIEALkLLATK--DDLLLVVFGKND- 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 373 heeyqQLIDDLKLDNVHLkGYVANP---APFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKYSPrELIKEHETG 449
Cdd:cd03825  236 -----PQIVILPFDIISL-GYIDDDeqlVDIYSAADLFVHPSLADNLPNTLLEAMACGTPVVAFDTGGSP-EIVQHGVTG 308

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 658531754 450 MLVEPDNIDMLAESIIYLYDNPERAIQYGKNAKNLMDTEYSEARLFERWEEVFE 503
Cdd:cd03825  309 YLVPPGDVQALAEAIEWLLANPKERESLGERARALAENHFDQRVQAQRYLELYK 362
GT4_BshA-like cd04962
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ...
 283-503 2.22e-15

N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340859 [Multi-domain]  Cd Length: 370  Bit Score: 77.78  E-value: 2.22e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 283 IKDYDGLIVLTNEQKEDIMKDFESNNNIFVIP-----------HAPRRLEKLQTYEKKKnEFVMVARYHEEKGIDKVIKA 351
Cdd:cd04962  139 INKSDRVTAVSSSLRQETYELFDVDKDIEVIHnfidedvfkrkPAGALKRRLLAPPDEK-VVIHVSNFRPVKRIDDVVRV 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 352 MGIVKKSRPDIVLNIyGSGPGHEEYQQLIDDLKL-DNVHLKGYVANPAPFYQQALATLLTSKFEGFSLAICESFSCATPV 430
Cdd:cd04962  218 FARVRRKIPAKLLLV-GDGPERVPAEELARELGVeDRVLFLGKQDDVEELLSIADLFLLPSEKESFGLAALEAMACGVPV 296

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 658531754 431 ISFDVKYSPrELIKEHETGMLVEPDNIDMLAESIIYLYDNPERAIQYGKNAKNLMDTEYSEARLFERWEEVFE 503
Cdd:cd04962  297 VSSNAGGIP-EVVKHGETGFLSDVGDVDAMAKSALSILEDDELYNRMGRAARKRAAERFDPERIVPQYEAYYR 368
GT4_ExpE7-like cd03823
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ...
 310-490 2.90e-15

glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).


Pssm-ID: 340850 [Multi-domain]  Cd Length: 357  Bit Score: 76.98  E-value: 2.90e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 310 IFVIPHA----PRRLEKLQTYEKKKNeFVMVARYHEEKGIDKVIKAmgiVKK-SRPDIVLNIYGSGPGHEEYQQLIDDlk 384
Cdd:cd03823  168 ISVIPNAvepdLAPPPRRRPGTERLR-FGYIGRLTEEKGIDLLVEA---FKRlPREDIELVIAGHGPLSDERQIEGGR-- 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 385 ldNVHLKGYV--ANPAPFYQQALATLLTSKF-EGFSLAICESFSCATPVISFDVKYSPrELIKEHETGMLVEPDNIDMLA 461
Cdd:cd03823  242 --RIAFLGRVptDDIKDFYEKIDVLVVPSIWpEPFGLVVREAIAAGLPVIASDLGGIA-ELIQPGVNGLLFAPGDAEDLA 318

                        170       180
                 ....*....|....*....|....*....
gi 658531754 462 ESIIYLYDNPERAIQYGKNAKNLMDTEYS 490
Cdd:cd03823  319 AAMRRLLTDPALLERLRAGAEPPRSTESQ 347
GT4_Bme6-like cd03821
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ...
 288-488 3.32e-13

Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.


Pssm-ID: 340848 [Multi-domain]  Cd Length: 377  Bit Score: 70.86  E-value: 3.32e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 288 GLIVLTNEQKEDIMKDFESNNNIFVIPHA--PRRLEKLQTYEKKKN------EFVMVARYHEEKGIDKVIKAMGIVKKSR 359
Cdd:cd03821  154 ALVHFTSEQEADELRRFGLEPPIAVIPNGvdIPEFDPGLRDRRKHNgledrrIILFLGRIHPKKGLDLLIRAARKLAEQG 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 360 PDIVLNIYGSGPGHEEY-QQLIDDLKLDN-VHLKGyvanpaPFYQQALATL--------LTSKFEGFSLAICESFSCATP 429
Cdd:cd03821  234 RDWHLVIAGPDDGAYPAfLQLQSSLGLGDrVTFTG------PLYGEAKWALyasadlfvLPSYSENFGNVVAEALACGLP 307

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 430 V-ISFDVKYSPrelIKEHETGMLVEPdNIDMLAESIIYLYDNPERAIQYGKNAKNLMDTE 488
Cdd:cd03821  308 VvITDKCGLSE---LVEAGCGVVVDP-NVSSLAEALAEALRDPADRKRLGEMARRARQVE 363
GT4_sucrose_synthase cd03800
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ...
 314-481 6.05e-13

sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.


Pssm-ID: 340830 [Multi-domain]  Cd Length: 398  Bit Score: 70.35  E-value: 6.05e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 314 PHAPRRLEKLQTYEKKKneFVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPG------HEEYQQLIDDLKL-D 386
Cdd:cd03800  206 RAEARRARLLLPPDKPV--VLALGRLDPRKGIDTLVRAFAQLPELRELANLVLVGGPSDdplsmdREELAELAEELGLiD 283

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 387 NVHLKGYVANP--APFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKySPRELIKEHETGMLVEPDNIDMLAESI 464
Cdd:cd03800  284 RVRFPGRVSRDdlPELYRAADVFVVPSLYEPFGLTAIEAMACGTPVVATAVG-GLQDIVRDGRTGLLVDPHDPEALAAAL 362

                        170
                 ....*....|....*..
gi 658531754 465 IYLYDNPERAIQYGKNA 481
Cdd:cd03800  363 RRLLDDPALWQRLSRAG 379
GT4_AmsK-like cd03799
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ...
 314-494 6.56e-13

Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.


Pssm-ID: 340829 [Multi-domain]  Cd Length: 350  Bit Score: 69.79  E-value: 6.56e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 314 PHAPRRLEKLQtyekkKNEFVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPGHEEYQQLIDDLKL-DNVHLKG 392
Cdd:cd03799  163 RFKPRYLPLDG-----KIRILTVGRLTEKKGLEYAIEAVAKLAQKYPNIEYQIIGDGDLKEQLQQLIQELNIgDCVKLLG 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 393 YVANPA--PFYQQA---LATLLTSK---FEGFSLAICESFSCATPVISFDVKYSPrELIKEHETGMLVEPDNIDMLAESI 464
Cdd:cd03799  238 WKPQEEiiEILDEAdifIAPSVTAAdgdQDGPPNTLKEAMAMGLPVISTEHGGIP-ELVEDGVSGFLVPERDAEAIAEKL 316

                        170       180       190
                 ....*....|....*....|....*....|
gi 658531754 465 IYLYDNPERAIQYGKNAKNLMDTEYSEARL 494
Cdd:cd03799  317 TYLIEHPAIWPEMGKAGRARVEEEYDINKL 346
PRK09922 PRK09922
lipopolysaccharide 1,6-galactosyltransferase;
216-465 2.13e-12

lipopolysaccharide 1,6-galactosyltransferase;


Pssm-ID: 182148 [Multi-domain]  Cd Length: 359  Bit Score: 68.58  E-value: 2.13e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 216 HTHWLETLCEKEKDPIIICDGVGSASKVNEMRAGLAKRFYCVHSNHLdypytlgsKVRTNHQYAMEHIKDYDGLIVLTNE 295
Cdd:PRK09922  72 HVYNFSKWLKETQPDIVICIDVISCLYANKARKKSGKQFKIFSWPHF--------SLDHKKHAECKKITCADYHLAISSG 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 296 QKEDIMKDFESNNNIFVI--PHAPRRLEKLQTYEKKKNEFVMVAR--YHEEKGIDKVIKAMGIVKKsrpDIVLNIYGSGP 371
Cdd:PRK09922 144 IKEQMMARGISAQRISVIynPVEIKTIIIPPPERDKPAVFLYVGRlkFEGQKNVKELFDGLSQTTG---EWQLHIIGDGS 220

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 372 GHEEYQQLIDDLKLD-NVHLKGYVANPAPFYQQAL----ATLLTSKFEGFSLAICESFSCATPVISFDVKYSPRELIKEH 446
Cdd:PRK09922 221 DFEKCKAYSRELGIEqRIIWHGWQSQPWEVVQQKIknvsALLLTSKFEGFPMTLLEAMSYGIPCISSDCMSGPRDIIKPG 300

                        250
                 ....*....|....*....
gi 658531754 447 ETGMLVEPDNIDMLAESII 465
Cdd:PRK09922 301 LNGELYTPGNIDEFVGKLN 319
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 333-502 3.04e-11

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 65.01  E-value: 3.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 333 FVMVARYHEEKGIDKVIKAMGIVKKSRPdIVLNIYGSGPGHEEYQQliddlKLDNVHLKGYvanpapFYQQALATLLTS- 411
Cdd:cd03814  201 LLYVGRLAPEKNLEALLDADLPLAASPP-VRLVVVGDGPARAELEA-----RGPDVIFTGF------LTGEELARAYASa 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 412 -------KFEGFSLAICESFSCATPVISFDVKySPRELIKEHETGMLVEPDNIDMLAESIIYLYDNPERAIQYGKNAknl 484
Cdd:cd03814  269 dvfvfpsRTETFGLVVLEAMASGLPVVAADAG-GPRDIVRPGGTGALVEPGDAAAFAAALRALLEDPELRRRMAARA--- 344

                        170
                 ....*....|....*...
gi 658531754 485 mdTEYSEARlfeRWEEVF 502
Cdd:cd03814  345 --RAEAERY---SWEAFL 357
GT4_WbdM_like cd04951
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ...
 329-502 8.65e-11

LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340857 [Multi-domain]  Cd Length: 360  Bit Score: 63.62  E-value: 8.65e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 329 KKNEFVM--VARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPGHEEYQQLIDDLKL-DNVHLKGYVANPAPFYQQAL 405
Cdd:cd04951  185 KNDEFVIlnVGRLTEAKDYPNLLLAISELILSKNDFKLLIAGDGPLRNELERLICNLNLvDRVILLGQISNISEYYNAAD 264

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 406 ATLLTSKFEGFSLAICESFSCATPVISFDVKySPRELIKEHEtgMLVEPDNIDMLAESIIYLYD-NPERAIQYGKNaKNL 484
Cdd:cd04951  265 LFVLSSEWEGFGLVVAEAMACERPVVATDAG-GVAEVVGDHN--YVVPVSDPQLLAEKIKEIFDmSDEERDILGNK-NEY 340

                        170
                 ....*....|....*...
gi 658531754 485 MDTEYSEARLFERWEEVF 502
Cdd:cd04951  341 IAKNFSINTIVNEWERLY 358
GT4_AviGT4-like cd03802
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ...
 328-454 3.97e-09

UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.


Pssm-ID: 340832 [Multi-domain]  Cd Length: 333  Bit Score: 58.07  E-value: 3.97e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 328 KKKNEFVMVARYHEEKGIDKVIKamgIVKKSRpdIVLNIYGSGPGHEEYQQLIDDLKLDNVHLKGYVANP--APFYQQAL 405
Cdd:cd03802  167 DPEDYLAFLGRIAPEKGLEDAIR---VARRAG--LPLKIAGKVRDEDYFYYLQEPLPGPRIEFIGEVGHDekQELLGGAR 241

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 658531754 406 ATLLTSKF-EGFSLAICESFSCATPVISFDvKYSPRELIKEHETGMLVEP 454
Cdd:cd03802  242 ALLFPINWdEPFGLVMIEAMACGTPVIAYR-RGGLPEVIQHGETGFLVDS 290
GT4-like cd05844
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ...
 333-467 1.65e-08

glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340860 [Multi-domain]  Cd Length: 365  Bit Score: 56.31  E-value: 1.65e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 333 FVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPGHEEYQQLIDDlkLDNVHLKGYVANP--APFYQQALATLLT 410
Cdd:cd05844  192 ILFVGRLVEKKGCDVLIEAFRRLAARHPTARLVIAGDGPLRPALQALAAA--LGRVRFLGALPHAevQDWMRRAEIFCLP 269

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 658531754 411 SKF------EGFSLAICESFSCATPVISFDVKYSPrELIKEHETGMLVEPDNIDMLAESIIYL 467
Cdd:cd05844  270 SVTaasgdsEGLGIVLLEAAACGVPVVSSRHGGIP-EAILDGETGFLVPEGDVDALADALQAL 331
GT4_PIG-A-like cd03796
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This ...
 284-502 1.94e-07

phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is an important cellular structure that facilitates the attachment of many proteins to cell surfaces. Somatic mutations in PIG-A have been associated with Paroxysmal Nocturnal Hemoglobinuria (PNH), an acquired hematological disorder.


Pssm-ID: 340827 [Multi-domain]  Cd Length: 398  Bit Score: 53.40  E-value: 1.94e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 284 KDYDGLIVLTNEQKED-IMKDFESNNNIFVIPHA-------PRRleklQTYEKKKNEFVMVARYHEEKGIDKVIKAMGIV 355
Cdd:cd03796  143 ADIDHVICVSHTSKENtVLRASLDPRIVSVIPNAvdssdftPDP----SKPDPNKITIVVISRLVYRKGIDLLVGIIPRI 218

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 356 KKSRPDIVLNIYGSGPGHEEYQQLIDDLKL-DNVHLKGYV--ANPAPFYQQALATLLTSKFEGFSLAICESFSCATPVIS 432
Cdd:cd03796  219 CKKHPNVRFIIGGDGPKRIELEEMREKYQLqDRVELLGAVphEEVRDVLVQGHIFLNTSLTEAFCIAIVEAASCGLLVVS 298

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 658531754 433 FDVKYSPrELIKEHETgMLVEPDNIDM---LAESIIYLYDNPERAIQYGKNAKNLmdteYSEARLFERWEEVF 502
Cdd:cd03796  299 TRVGGIP-EVLPPDMI-LLAEPDPEDIvrkLEEAISILRTGKHDPWSFHNRVKKM----YSWEDVARRTEKVY 365
GT4_ExpC-like cd03818
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 ...
 314-498 3.61e-07

Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).


Pssm-ID: 340845 [Multi-domain]  Cd Length: 396  Bit Score: 52.37  E-value: 3.61e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 314 PHAPRRLEKLQTYEKKKNEFVMVARYHEE-KGIDKVIKAMGIVKKSRPD--IVL-----NIYGSGPGHEEY--QQLIDDL 383
Cdd:cd03818  197 PAARLRLLNGTELKAGDPVITYVARNLEPyRGFHVFMRALPRIQARRPDarVVVvggdgVSYGSPPPDGGSwkQKMLAEL 276

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 384 KLD--NVHLKGYVanPAPFYQQALA-----TLLTSKFEgFSLAICESFSCATPVISFDVKysP-RELIKEHETGMLVEPD 455
Cdd:cd03818  277 GVDleRVHFVGKV--PYDQYVRLLQlsdahVYLTYPFV-LSWSLLEAMACGCPVIGSDTA--PvREVIRDGRNGLLVDFF 351

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 658531754 456 NIDMLAESIIYLYDNPERAIQYGKNAKNlmdteYSEARLFERW 498
Cdd:cd03818  352 DPDALAAAVLELLEDPDRAAALRRAARR-----TVERSDSLDV 389
GT4_trehalose_phosphorylase cd03792
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ...
 333-498 4.78e-07

trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.


Pssm-ID: 340823 [Multi-domain]  Cd Length: 378  Bit Score: 51.94  E-value: 4.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 333 FVMVARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGP--GHE---------EYQQLIDDLKLdnvhlkgyVANPAP-- 399
Cdd:cd03792  200 ILQVARFDPSKDPLGVIDAYKLFKRRAEEPQLVICGHGAvdDPEgsvvyeevmEYAGDDHDIHV--------LRLPPSdq 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 400 ----FYQQALATLLTSKFEGFSLAICESFSCATPVISFDVKYSPRElIKEHETGMLVepDNIDMLAESIIYLYDNPERAI 475
Cdd:cd03792  272 einaLQRAATVVLQLSTREGFGLTVSEALWKGKPVIATPAGGIPLQ-VIDGETGFLV--NSVEGAAVRILRLLTDPELRR 348

                        170       180
                 ....*....|....*....|...
gi 658531754 476 QYGKNAKNLMDTEYSEARLFERW 498
Cdd:cd03792  349 KMGLAAREHVRDNFLITGNLRAW 371
GT33_ALG1-like cd03816
chitobiosyldiphosphodolichol beta-mannosyltransferase and similar proteins; This family is ...
 356-501 8.45e-06

chitobiosyldiphosphodolichol beta-mannosyltransferase and similar proteins; This family is most closely related to the GT33 family of glycosyltransferases. The yeast gene ALG1 has been shown to function as a mannosyltransferase that catalyzes the formation of dolichol pyrophosphate (Dol-PP)-GlcNAc2Man from GDP-Man and Dol-PP-Glc-NAc2, and participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. In humans ALG1 has been associated with the congenital disorders of glycosylation (CDG) designated as subtype CDG-Ik.


Pssm-ID: 340843 [Multi-domain]  Cd Length: 411  Bit Score: 48.04  E-value: 8.45e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 356 KKSRPDIVLNIYGSGPGHEEYQQLIDDLKLDNVHLKgYVANPAPFYQQALA------TLLTSKfEGFSL--AICESFSCA 427
Cdd:cd03816  261 PALLPSLLCIITGKGPLKEMYLELIKELKLKKVTIR-TPWLSAEDYPRLLAsadlgvCLHTSS-SGLDLpmKVVDMFGCG 338

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 658531754 428 TPVISFDvKYSPRELIKEHETGMLVEpdNIDMLAESIIYLYDNPERAiQYGKNAKNLMdtEYSEARLFERWEEV 501
Cdd:cd03816  339 LPVCAMD-FKCIGELVKHGVNGLVFG--DSEELAEQLIDLLSDFDRG-KLNVLKKGAQ--EESENRWDENWDRV 406
GT4_mannosyltransferase-like cd03822
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most ...
 306-473 1.53e-05

mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.


Pssm-ID: 340849 [Multi-domain]  Cd Length: 370  Bit Score: 46.99  E-value: 1.53e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 306 SNNNIFVIPHA-PRRLEKLQTYEKK----KNEFVMVA----RYHeeKGIDKVIKAMGIVKKSRPDIVLNI----YGSGPG 372
Cdd:cd03822  156 PAVNIEVIPHGvPEVPQDPTTALKRlllpEGKKVILTfgfiGPG--KGLEILLEALPELKAEFPDVRLVIagelHPSLAR 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 373 H--EEYQQLIDDLKL--DNV--HLKGYVANPAPFYQQAlATLL----TSKFEGFSLAICESFSCATPVISFDVKYSpREL 442
Cdd:cd03822  234 YegERYRKAAIEELGlqDHVdfHNNFLPEEEVPRYISA-ADVVvlpyLNTEQSSSGTLSYAIACGKPVISTPLRHA-EEL 311

                        170       180       190
                 ....*....|....*....|....*....|.
gi 658531754 443 IKEhETGMLVEPDNIDMLAESIIYLYDNPER 473
Cdd:cd03822  312 LAD-GRGVLVPFDDPSAIAEAILRLLEDDER 341
GT4_ALG2-like cd03805
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ...
 290-482 1.86e-05

alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.


Pssm-ID: 340834 [Multi-domain]  Cd Length: 392  Bit Score: 46.81  E-value: 1.86e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 290 IVLTNEQKEDIMKDFESNNNIFViphaprrleKLQTYEKKKNefvmvaryheekgIDKVIKAMGIVKK---SRPDIVLNI 366
Cdd:cd03805  193 FDSTSEDPDPGDLIAKSNKKFFL---------SINRFERKKN-------------IALAIEAFAKLKQklpEFENVRLVI 250

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 367 YGsgpG-----------HEEYQQLIDDLKLDNVH----------LKGYVanpapfYQQALATLLTSKFEGFSLAICESFS 425
Cdd:cd03805  251 AG---GydprvaenveyLEELQRLAEELLNVEDQvlflrsisdsQKEQL------LSSALALLYTPSNEHFGIVPLEAMY 321

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 658531754 426 CATPVISFDvkyS--PRELIKEHETGMLVEPdNIDMLAESIIYLYDNPERAIQYGKNAK 482
Cdd:cd03805  322 AGKPVIACN---SggPLETVVEGVTGFLCEP-TPEAFAEAMLKLANDPDLADRMGAAGR 376
GT4_CapH-like cd03812
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ...
 321-436 2.86e-05

capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).


Pssm-ID: 340840 [Multi-domain]  Cd Length: 357  Bit Score: 46.13  E-value: 2.86e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 321 EKLQTYEKKKNEFVM--VARYHEEKGIDKVIKAMGIVKKSRPDIVLNIYGSGPGHEEYQQLIDDLKL-DNVHLKGYVANP 397
Cdd:cd03812  180 RKRRKLLILEDKLVLghVGRFNEQKNHSFLIDIFEELKKKNPNVKLVLVGEGELKEKIKEKVKELGLeDKVIFLGFRNDV 259

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 658531754 398 APFYQQALATLLTSKFEGFSLAICESFSCATPVISFDVK 436
Cdd:cd03812  260 SEILSAMDVFLFPSLYEGLPLVAVEAQASGLPCLLSDTI 298
GT4_AmsK-like cd04946
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ...
 343-490 4.23e-05

amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.


Pssm-ID: 340854 [Multi-domain]  Cd Length: 401  Bit Score: 45.91  E-value: 4.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 343 KGIDKVIKAMGIVKKSRPDIvlNI----YGSGPGHEEYQQLIDD-LKLDNVHLKGYVANPA--PFYQQALATLLT--SKF 413
Cdd:cd04946  237 KRIDLIIETLNSLCVAHPSI--CIswthIGGGPLKERLEKLAENkLENVKVNFTGEVSNKEvkQLYKENDVDVFVnvSES 314

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 658531754 414 EGFSLAICESFSCATPVISFDVKySPRELIKEHETGMLVEPDNIDM-LAESIIYLYDNPERAIQYGKNAKNLMDTEYS 490
Cdd:cd04946  315 EGIPVSIMEAISFGIPVIATNVG-GTREIVENETNGLLLDKDPTPNeIVSSIMKFYLDGGDYKTMKISARECWEERFN 391
Glyco_trans_A_1 pfam09318
Glycosyl transferase 1 domain A; Glyco_trans_A_1 is family of found predominantly at the ...
 16-186 9.13e-05

Glycosyl transferase 1 domain A; Glyco_trans_A_1 is family of found predominantly at the N-terminus of various prokaryotic alpha-glucosyltransferases. According to whether the domain exists as a whole molecule or as a half molecule determines the number of sugar residues that the molecule transfers. Two-domain proteins are processive in that they transfer more than one sugar residue, processively; single domain proteins transfer just one sugar moiety.


Pssm-ID: 370428  Cd Length: 199  Bit Score: 43.49  E-value: 9.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754   16 GGITSSMMSRSFTFAERGHK-IDLVTLDYKDNYDQIEQVLKSAGRLHADV-NILNIYDDY-------KNQHKHiKIGEVQ 86
Cdd:pfam09318  12 GGLTKSLLLRAKLFGEECNInTFFLTFRFDLEFSQKIDEIFDKGIIDKKFtKIINLFDDFlipncngKEQYEE-RIGLDQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754   87 QSYYDQNrNRFEEPYAAYHNEEKLETEYFKNGlyikkkkwdESDNLLYVDHFNENMQMTKR-EFFQGGYVNKTVIFDTRS 165
Cdd:pfam09318  91 IKKHAGM-GKFAKTLLRLFDHEDNEMRMIRNE---------DGEQIEIVDYFHDKNQLEKReEYNKNGNLHKVSHFDQEL 160

                         170       180
                  ....*....|....*....|.
gi 658531754  166 GKINQIHYTAPDGFCYLTEWY 186
Cdd:pfam09318 161 GKMYLEEFINDNNHIYLDKGY 181
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 343-502 1.71e-04

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 44.15  E-value: 1.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 343 KGIDKVIKAMGIVKKSRPD----IVlniygsGPGHE--EYQQ----LIDDLKL-DNVHLKGY--VANPAPfyqQALATLL 409
Cdd:NF038011 319 KDIKTFIRAMRTVVRAMPEaegwIV------GPEEEdpAYAAecrsLVASLGLqDKVKFLGFqkIDDLLP---QVGLMVL 389

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 410 TSKFEGFSLAICESFSCATPVISFDVKySPRELIKEHET--------GMLVEPDNIDMLAESIIYLYDNPER--AIQygk 479
Cdd:NF038011 390 SSISEALPLVVLEAFAAGVPVVTTDVG-SCRQLIEGLDEedralgaaGEVVAIADPQALARAALDLLRDPQRwqAAQ--- 465

                        170       180
                 ....*....|....*....|....*
gi 658531754 480 nAKNLMDTE--YSEARLFERWEEVF 502
Cdd:NF038011 466 -AAGLARVEryYTEELMFDRYRELY 489
GT4_WbaZ-like cd03804
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ...
 312-497 2.11e-04

mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.


Pssm-ID: 340833 [Multi-domain]  Cd Length: 356  Bit Score: 43.43  E-value: 2.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 312 VIpHAPRRLEKLQTYEKKKNEFVMVARYHEEKGIDKVIKA---MGivkksRPDIVLniyGSGPGHEEyqqlIDDLKLDNV 388
Cdd:cd03804  182 VI-YPPVDTDAFAPAADKEDYYLTASRLVPYKRIDLAVEAfneLP-----KRLVVI---GDGPDLDR----LRAMASPNV 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 389 HLKGYVANP--APFYQQALATLLTSKfEGFSLAICESFSCATPVISFDvKYSPRELIKEHETGMLVEPDNIDMLAESIIY 466
Cdd:cd03804  249 EFLGYQPDEvlKELLSKARAFVFAAE-EDFGIVPVEAQACGTPVIAFG-KGGALETVRPGPTGILFGEQTVESLKAAVEE 326

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 658531754 467 LYDNPER----AIQygKNAknlmdTEYSEARlFER 497
Cdd:cd03804  327 FEQNFDRfkpqAIR--ANA-----ERFSRAR-FRQ 353
PRK15179 PRK15179
Vi polysaccharide biosynthesis protein TviE; Provisional
 349-469 4.43e-04

Vi polysaccharide biosynthesis protein TviE; Provisional


Pssm-ID: 185101 [Multi-domain]  Cd Length: 694  Bit Score: 43.10  E-value: 4.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658531754 349 IKAMGIVKKSRPDIVLNIYGSGPGHEEYQQLIDDLKL-DNVHLKGYVANPAPFYQQALATLLTSKFEGFSLAICESFSCA 427
Cdd:PRK15179 536 VEAAQRFAASHPKVRFIMVGGGPLLESVREFAQRLGMgERILFTGLSRRVGYWLTQFNAFLLLSRFEGLPNVLIEAQFSG 615

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 658531754 428 TPVISfDVKYSPRELIKEHETGMLVEPDNIDM--LAESIIYLYD 469
Cdd:PRK15179 616 VPVVT-TLAGGAGEAVQEGVTGLTLPADTVTApdVAEALARIHD 658
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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