|
Name |
Accession |
Description |
Interval |
E-value |
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
7-406 |
0e+00 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 539.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 7 NITKIRNDFPtlnqtLNGNPLVYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNVN 86
Cdd:COG0520 1 DVEAIRADFP-----VLGKPLVYLDNAATGQKPRPVIDAIRDYYEPYNANVHRGAHELSAEATDAYEAAREKVARFIGAA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 87 -AKEIVWTKSATEALNLLAHGLQRqITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPLEQNATFNIARCIDMITHt 165
Cdd:COG0520 76 sPDEIIFTRGTTEAINLVAYGLGR-LKPGDEILITEMEHHSNIVPWQELAERTGAEVRVIPLDEDGELDLEALEALLTP- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 166 KAKVLCISQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYELL 245
Cdd:COG0520 154 RTKLVAVTHVSNVTGTVNPVKEIAALAHAHGALVLVDGAQSVPHLPVDVQALGCDFYAFSGHKLYGPTGIGVLYGKRELL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 246 NALTPYQTGGEMIDTVTLEKSTYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEIDGIT 325
Cdd:COG0520 234 EALPPFLGGGGMIEWVSFDGTTYADLPRRFEAGTPNIAGAIGLGAAIDYLEAIGMEAIEARERELTAYALEGLAAIPGVR 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 326 IY--SDLNNNIGTLSFNYKSEHPYDLATLLDGFGIAVRSGHHCTQPLMHHLGVKGTVRASFAFYNTHQDVDNFINALKES 403
Cdd:COG0520 314 ILgpADPEDRSGIVSFNVDGVHPHDVAALLDDEGIAVRAGHHCAQPLMRRLGVPGTVRASFHLYNTEEEIDRLVEALKKL 393
|
...
gi 658750212 404 IEL 406
Cdd:COG0520 394 AEL 396
|
|
| sufS |
TIGR01979 |
cysteine desulfurases, SufSfamily; This model represents a subfamily of NifS-related cysteine ... |
9-407 |
0e+00 |
|
cysteine desulfurases, SufSfamily; This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]
Pssm-ID: 131034 [Multi-domain] Cd Length: 403 Bit Score: 531.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 9 TKIRNDFPTLNQTLNGNPLVYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNVN-A 87
Cdd:TIGR01979 1 KNIRADFPILKRKINGKPLVYLDSAATSQKPQQVIDAVAEYYRNSNANVHRGIHTLSVRATEAYEAVREKVAKFINAAsD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 88 KEIVWTKSATEALNLLAHGLQR-QITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPLEQNATFNIARCIDMIThTK 166
Cdd:TIGR01979 81 EEIVFTRGTTESINLVAYSWGDsNLKAGDEIVISEMEHHANIVPWQLLAERTGATLKFIPLDDDGTLDLDDLEKLLT-EK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 167 AKVLCISQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYELLN 246
Cdd:TIGR01979 160 TKLVAITHVSNVLGTVNPVEEIAKLAHQVGAKVLVDGAQAVPHMPVDVQALDCDFYVFSGHKMYGPTGIGVLYGKEELLE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 247 ALTPYQTGGEMIDTVTLEKSTYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEIDGITI 326
Cdd:TIGR01979 240 QMPPFLGGGEMIAEVSFEETTYNEAPHKFEAGTPNIAGVIGLGAAIDYLEAIGLENIEAHEHELTAYALERLGEIPGLRI 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 327 YSDLNNN--IGTLSFNYKSEHPYDLATLLDGFGIAVRSGHHCTQPLMHHLGVKGTVRASFAFYNTHQDVDNFINALKESI 404
Cdd:TIGR01979 320 YGPRDAEdrGGIISFNVEGVHPHDVGTILDEEGIAVRSGHHCAQPLMRRFGVPATCRASFYIYNTEEDIDALVEALKKVR 399
|
...
gi 658750212 405 ELL 407
Cdd:TIGR01979 400 KFF 402
|
|
| SufS_like |
cd06453 |
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP) ... |
28-400 |
0e+00 |
|
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine; and selenocysteine lyase catalyzes the decomposition of L-selenocysteine.
Pssm-ID: 99746 [Multi-domain] Cd Length: 373 Bit Score: 513.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 28 VYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNV-NAKEIVWTKSATEALNLLAHG 106
Cdd:cd06453 1 VYLDNAATSQKPQPVIDAIVDYYRHYNANVHRGVHELSARATDAYEAAREKVARFINApSPDEIIFTRNTTEAINLVAYG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 107 LQRQITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPLEQNATFNIARCIDMIThTKAKVLCISQASNALGNITNLA 186
Cdd:cd06453 81 LGRANKPGDEIVTSVMEHHSNIVPWQQLAERTGAKLKVVPVDDDGQLDLEALEKLLT-ERTKLVAVTHVSNVLGTINPVK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 187 PLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYELLNALTPYQTGGEMIDTVTLEKS 266
Cdd:cd06453 160 EIGEIAHEAGVPVLVDGAQSAGHMPVDVQDLGCDFLAFSGHKMLGPTGIGVLYGKEELLEEMPPYGGGGEMIEEVSFEET 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 267 TYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEIDGITIYSDLNNNIGTLSFNYKSEHP 346
Cdd:cd06453 240 TYADLPHKFEAGTPNIAGAIGLGAAIDYLEKIGMEAIAAHEHELTAYALERLSEIPGVRVYGDAEDRAGVVSFNLEGIHP 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 658750212 347 YDLATLLDGFGIAVRSGHHCTQPLMHHLGVKGTVRASFAFYNTHQDVDNFINAL 400
Cdd:cd06453 320 HDVATILDQYGIAVRAGHHCAQPLMRRLGVPGTVRASFGLYNTEEEIDALVEAL 373
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
28-396 |
2.68e-158 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 450.55 E-value: 2.68e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 28 VYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNV-NAKEIVWTKSATEALNLLAHG 106
Cdd:pfam00266 1 IYLDSAATTQKPQEVLDAIQEYYTDYNGNVHRGVHTLGKEATQAYEEAREKVAEFINApSNDEIIFTSGTTEAINLVALS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 107 LQRQITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPLEQNATFNIARCIDMITHtKAKVLCISQASNALGNITNLA 186
Cdd:pfam00266 81 LGRSLKPGDEIVITEMEHHANLVPWQELAKRTGARVRVLPLDEDGLLDLDELEKLITP-KTKLVAITHVSNVTGTIQPVP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 187 PLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYELLNALTPYQTGGEMIDTVTLEKS 266
Cdd:pfam00266 160 EIGKLAHQYGALVLVDAAQAIGHRPIDVQKLGVDFLAFSGHKLYGPTGIGVLYGRRDLLEKMPPLLGGGGMIETVSLQES 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 267 TYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEIDGITIYSDLNNNiGTLSFNYKSEHP 346
Cdd:pfam00266 240 TFADAPWKFEAGTPNIAGIIGLGAALEYLSEIGLEAIEKHEHELAQYLYERLLSLPGIRLYGPERRA-SIISFNFKGVHP 318
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 658750212 347 YDLATLLDGFGIAVRSGHHCTQPLMHHLGVKGTVRASFAFYNTHQDVDNF 396
Cdd:pfam00266 319 HDVATLLDESGIAVRSGHHCAQPLMVRLGLGGTVRASFYIYNTQEDVDRL 368
|
|
| PLN02855 |
PLN02855 |
Bifunctional selenocysteine lyase/cysteine desulfurase |
9-408 |
3.80e-155 |
|
Bifunctional selenocysteine lyase/cysteine desulfurase
Pssm-ID: 215460 [Multi-domain] Cd Length: 424 Bit Score: 444.58 E-value: 3.80e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 9 TKIRNDFPTLNQTLNGNPLVYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNV-NA 87
Cdd:PLN02855 15 AETRPDFPILDQTVNGSKLVYLDNAATSQKPAAVLDALQDYYEEYNSNVHRGIHALSAKATDAYELARKKVAAFINAsTS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 88 KEIVWTKSATEALNLLAH--GLQrQITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPLEQNATFNIARCIDMITHt 165
Cdd:PLN02855 95 REIVFTRNATEAINLVAYtwGLA-NLKPGDEVILSVAEHHSNIVPWQLVAQKTGAVLKFVGLTPDEVLDVEQLKELLSE- 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 166 KAKVLCISQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYELL 245
Cdd:PLN02855 173 KTKLVATHHVSNVLGSILPVEDIVHWAHAVGAKVLVDACQSVPHMPVDVQTLGADFLVASSHKMCGPTGIGFLWGKSDLL 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 246 NALTPYQTGGEMIDTVTLEKSTYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEIDGIT 325
Cdd:PLN02855 253 ESMPPFLGGGEMISDVFLDHSTYAPPPSRFEAGTPAIGEAIGLGAAIDYLSEIGMDRIHEYEVELGTYLYEKLSSVPGVR 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 326 IY----SDLNNNIGTLSFNYKSEHPYDLATLLD-GFGIAVRSGHHCTQPLMHHLGVKGTVRASFAFYNTHQDVDNFINAL 400
Cdd:PLN02855 333 IYgpkpSEGVGRAALCAFNVEGIHPTDLSTFLDqQHGVAIRSGHHCAQPLHRYLGVNASARASLYFYNTKEEVDAFIHAL 412
|
....*...
gi 658750212 401 KESIELLD 408
Cdd:PLN02855 413 KDTIAFFS 420
|
|
| f2_encap_cargo1 |
NF041166 |
family 2A encapsulin nanocompartment cargo protein cysteine desulfurase; Capsid-like ... |
6-400 |
2.18e-146 |
|
family 2A encapsulin nanocompartment cargo protein cysteine desulfurase; Capsid-like encapsulin nanocompartments are commonly found in bacteria and archaea. Encapsulin nanocompartments, which are assembled from shell proteins, encapsulate various cargo proteins, typically peroxidases or ferritin-like proteins, to protect cells from oxidative stress caused by peroxide. Proteins of this family are cysteine desulfurases with an additional N-terminal encapsulation targeting sequence (~200 aa) that is necessary and sufficient for compartmentalization.
Pssm-ID: 469077 [Multi-domain] Cd Length: 623 Bit Score: 429.27 E-value: 2.18e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 6 FNITKIRNDFPTLNQTLNGNPLVYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNV 85
Cdd:NF041166 225 FDVNAVRRDFPILQERVNGKPLVWFDNAATTQKPQAVIDRLSYFYEHENSNIHRAAHELAARATDAYEGAREKVRRFIGA 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 86 -NAKEIVWTKSATEALNLLAHGLQRQITGE-DTVLITPLEHHANIVPWQVLTQNTGATLSALP--------LEQNAtfni 155
Cdd:NF041166 305 pSVDEIIFVRGTTEAINLVAKSWGRQNIGAgDEIIVSHLEHHANIVPWQQLAQETGAKLRVIPvddsgqilLDEYA---- 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 156 arciDMITHtKAKVLCISQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGV 235
Cdd:NF041166 381 ----KLLNP-RTKLVSVTQVSNALGTVTPVKEIIALAHRAGAKVLVDGAQSVSHMPVDVQALDADFFVFSGHKVFGPTGI 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 236 GGLYGRYELLNALTPYQTGGEMIDTVTLEKSTYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAA 315
Cdd:NF041166 456 GVVYGKRDLLEAMPPWQGGGNMIADVTFEKTVYQPAPNRFEAGTGNIADAVGLGAALDYVERIGIENIARYEHDLLEYAT 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 316 TQLSEIDGITIysdlnnnIGT-------LSFN---YKSEhpyDLATLLDGFGIAVRSGHHCTQPLMHHLGVKGTVRASFA 385
Cdd:NF041166 536 AGLAEVPGLRL-------IGTaadkasvLSFVldgYSTE---EVGKALNQEGIAVRSGHHCAQPILRRFGVEATVRPSLA 605
|
410
....*....|....*
gi 658750212 386 FYNTHQDVDNFINAL 400
Cdd:NF041166 606 FYNTCEEVDALVAVL 620
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
7-406 |
0e+00 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 539.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 7 NITKIRNDFPtlnqtLNGNPLVYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNVN 86
Cdd:COG0520 1 DVEAIRADFP-----VLGKPLVYLDNAATGQKPRPVIDAIRDYYEPYNANVHRGAHELSAEATDAYEAAREKVARFIGAA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 87 -AKEIVWTKSATEALNLLAHGLQRqITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPLEQNATFNIARCIDMITHt 165
Cdd:COG0520 76 sPDEIIFTRGTTEAINLVAYGLGR-LKPGDEILITEMEHHSNIVPWQELAERTGAEVRVIPLDEDGELDLEALEALLTP- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 166 KAKVLCISQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYELL 245
Cdd:COG0520 154 RTKLVAVTHVSNVTGTVNPVKEIAALAHAHGALVLVDGAQSVPHLPVDVQALGCDFYAFSGHKLYGPTGIGVLYGKRELL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 246 NALTPYQTGGEMIDTVTLEKSTYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEIDGIT 325
Cdd:COG0520 234 EALPPFLGGGGMIEWVSFDGTTYADLPRRFEAGTPNIAGAIGLGAAIDYLEAIGMEAIEARERELTAYALEGLAAIPGVR 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 326 IY--SDLNNNIGTLSFNYKSEHPYDLATLLDGFGIAVRSGHHCTQPLMHHLGVKGTVRASFAFYNTHQDVDNFINALKES 403
Cdd:COG0520 314 ILgpADPEDRSGIVSFNVDGVHPHDVAALLDDEGIAVRAGHHCAQPLMRRLGVPGTVRASFHLYNTEEEIDRLVEALKKL 393
|
...
gi 658750212 404 IEL 406
Cdd:COG0520 394 AEL 396
|
|
| sufS |
TIGR01979 |
cysteine desulfurases, SufSfamily; This model represents a subfamily of NifS-related cysteine ... |
9-407 |
0e+00 |
|
cysteine desulfurases, SufSfamily; This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]
Pssm-ID: 131034 [Multi-domain] Cd Length: 403 Bit Score: 531.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 9 TKIRNDFPTLNQTLNGNPLVYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNVN-A 87
Cdd:TIGR01979 1 KNIRADFPILKRKINGKPLVYLDSAATSQKPQQVIDAVAEYYRNSNANVHRGIHTLSVRATEAYEAVREKVAKFINAAsD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 88 KEIVWTKSATEALNLLAHGLQR-QITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPLEQNATFNIARCIDMIThTK 166
Cdd:TIGR01979 81 EEIVFTRGTTESINLVAYSWGDsNLKAGDEIVISEMEHHANIVPWQLLAERTGATLKFIPLDDDGTLDLDDLEKLLT-EK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 167 AKVLCISQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYELLN 246
Cdd:TIGR01979 160 TKLVAITHVSNVLGTVNPVEEIAKLAHQVGAKVLVDGAQAVPHMPVDVQALDCDFYVFSGHKMYGPTGIGVLYGKEELLE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 247 ALTPYQTGGEMIDTVTLEKSTYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEIDGITI 326
Cdd:TIGR01979 240 QMPPFLGGGEMIAEVSFEETTYNEAPHKFEAGTPNIAGVIGLGAAIDYLEAIGLENIEAHEHELTAYALERLGEIPGLRI 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 327 YSDLNNN--IGTLSFNYKSEHPYDLATLLDGFGIAVRSGHHCTQPLMHHLGVKGTVRASFAFYNTHQDVDNFINALKESI 404
Cdd:TIGR01979 320 YGPRDAEdrGGIISFNVEGVHPHDVGTILDEEGIAVRSGHHCAQPLMRRFGVPATCRASFYIYNTEEDIDALVEALKKVR 399
|
...
gi 658750212 405 ELL 407
Cdd:TIGR01979 400 KFF 402
|
|
| SufS_like |
cd06453 |
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP) ... |
28-400 |
0e+00 |
|
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine; and selenocysteine lyase catalyzes the decomposition of L-selenocysteine.
Pssm-ID: 99746 [Multi-domain] Cd Length: 373 Bit Score: 513.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 28 VYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNV-NAKEIVWTKSATEALNLLAHG 106
Cdd:cd06453 1 VYLDNAATSQKPQPVIDAIVDYYRHYNANVHRGVHELSARATDAYEAAREKVARFINApSPDEIIFTRNTTEAINLVAYG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 107 LQRQITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPLEQNATFNIARCIDMIThTKAKVLCISQASNALGNITNLA 186
Cdd:cd06453 81 LGRANKPGDEIVTSVMEHHSNIVPWQQLAERTGAKLKVVPVDDDGQLDLEALEKLLT-ERTKLVAVTHVSNVLGTINPVK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 187 PLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYELLNALTPYQTGGEMIDTVTLEKS 266
Cdd:cd06453 160 EIGEIAHEAGVPVLVDGAQSAGHMPVDVQDLGCDFLAFSGHKMLGPTGIGVLYGKEELLEEMPPYGGGGEMIEEVSFEET 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 267 TYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEIDGITIYSDLNNNIGTLSFNYKSEHP 346
Cdd:cd06453 240 TYADLPHKFEAGTPNIAGAIGLGAAIDYLEKIGMEAIAAHEHELTAYALERLSEIPGVRVYGDAEDRAGVVSFNLEGIHP 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 658750212 347 YDLATLLDGFGIAVRSGHHCTQPLMHHLGVKGTVRASFAFYNTHQDVDNFINAL 400
Cdd:cd06453 320 HDVATILDQYGIAVRAGHHCAQPLMRRLGVPGTVRASFGLYNTEEEIDALVEAL 373
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
28-396 |
2.68e-158 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 450.55 E-value: 2.68e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 28 VYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNV-NAKEIVWTKSATEALNLLAHG 106
Cdd:pfam00266 1 IYLDSAATTQKPQEVLDAIQEYYTDYNGNVHRGVHTLGKEATQAYEEAREKVAEFINApSNDEIIFTSGTTEAINLVALS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 107 LQRQITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPLEQNATFNIARCIDMITHtKAKVLCISQASNALGNITNLA 186
Cdd:pfam00266 81 LGRSLKPGDEIVITEMEHHANLVPWQELAKRTGARVRVLPLDEDGLLDLDELEKLITP-KTKLVAITHVSNVTGTIQPVP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 187 PLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYELLNALTPYQTGGEMIDTVTLEKS 266
Cdd:pfam00266 160 EIGKLAHQYGALVLVDAAQAIGHRPIDVQKLGVDFLAFSGHKLYGPTGIGVLYGRRDLLEKMPPLLGGGGMIETVSLQES 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 267 TYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEIDGITIYSDLNNNiGTLSFNYKSEHP 346
Cdd:pfam00266 240 TFADAPWKFEAGTPNIAGIIGLGAALEYLSEIGLEAIEKHEHELAQYLYERLLSLPGIRLYGPERRA-SIISFNFKGVHP 318
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 658750212 347 YDLATLLDGFGIAVRSGHHCTQPLMHHLGVKGTVRASFAFYNTHQDVDNF 396
Cdd:pfam00266 319 HDVATLLDESGIAVRSGHHCAQPLMVRLGLGGTVRASFYIYNTQEDVDRL 368
|
|
| PLN02855 |
PLN02855 |
Bifunctional selenocysteine lyase/cysteine desulfurase |
9-408 |
3.80e-155 |
|
Bifunctional selenocysteine lyase/cysteine desulfurase
Pssm-ID: 215460 [Multi-domain] Cd Length: 424 Bit Score: 444.58 E-value: 3.80e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 9 TKIRNDFPTLNQTLNGNPLVYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNV-NA 87
Cdd:PLN02855 15 AETRPDFPILDQTVNGSKLVYLDNAATSQKPAAVLDALQDYYEEYNSNVHRGIHALSAKATDAYELARKKVAAFINAsTS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 88 KEIVWTKSATEALNLLAH--GLQrQITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPLEQNATFNIARCIDMITHt 165
Cdd:PLN02855 95 REIVFTRNATEAINLVAYtwGLA-NLKPGDEVILSVAEHHSNIVPWQLVAQKTGAVLKFVGLTPDEVLDVEQLKELLSE- 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 166 KAKVLCISQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYELL 245
Cdd:PLN02855 173 KTKLVATHHVSNVLGSILPVEDIVHWAHAVGAKVLVDACQSVPHMPVDVQTLGADFLVASSHKMCGPTGIGFLWGKSDLL 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 246 NALTPYQTGGEMIDTVTLEKSTYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEIDGIT 325
Cdd:PLN02855 253 ESMPPFLGGGEMISDVFLDHSTYAPPPSRFEAGTPAIGEAIGLGAAIDYLSEIGMDRIHEYEVELGTYLYEKLSSVPGVR 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 326 IY----SDLNNNIGTLSFNYKSEHPYDLATLLD-GFGIAVRSGHHCTQPLMHHLGVKGTVRASFAFYNTHQDVDNFINAL 400
Cdd:PLN02855 333 IYgpkpSEGVGRAALCAFNVEGIHPTDLSTFLDqQHGVAIRSGHHCAQPLHRYLGVNASARASLYFYNTKEEVDAFIHAL 412
|
....*...
gi 658750212 401 KESIELLD 408
Cdd:PLN02855 413 KDTIAFFS 420
|
|
| PRK09295 |
PRK09295 |
cysteine desulfurase SufS; |
6-407 |
1.54e-146 |
|
cysteine desulfurase SufS;
Pssm-ID: 181766 [Multi-domain] Cd Length: 406 Bit Score: 421.85 E-value: 1.54e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 6 FNITKIRNDFPTLNQTLNGNPLVYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFN- 84
Cdd:PRK09295 3 FSVEKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKQAALFINa 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 85 VNAKEIVWTKSATEALNLLAHGLQR-QITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPLEQNATFNIARcIDMIT 163
Cdd:PRK09295 83 RSAEELVFVRGTTEGINLVANSWGNsNVRAGDNIIISEMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLET-LPALF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 164 HTKAKVLCISQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYE 243
Cdd:PRK09295 162 DERTRLLAITHVSNVLGTENPLAEMIALAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKEA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 244 LLNALTPYQTGGEMIDTVTL-EKSTYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEID 322
Cdd:PRK09295 242 LLQEMPPWEGGGSMIATVSLtEGTTWAKAPWRFEAGTPNTGGIIGLGAALDYVSALGLNNIAEYEQNLMHYALSQLESVP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 323 GITIYSDlNNNIGTLSFNYKSEHPYDLATLLDGFGIAVRSGHHCTQPLMHHLGVKGTVRASFAFYNTHQDVDNFINALKE 402
Cdd:PRK09295 322 DLTLYGP-QNRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVAGLQR 400
|
....*
gi 658750212 403 SIELL 407
Cdd:PRK09295 401 IHRLL 405
|
|
| f2_encap_cargo1 |
NF041166 |
family 2A encapsulin nanocompartment cargo protein cysteine desulfurase; Capsid-like ... |
6-400 |
2.18e-146 |
|
family 2A encapsulin nanocompartment cargo protein cysteine desulfurase; Capsid-like encapsulin nanocompartments are commonly found in bacteria and archaea. Encapsulin nanocompartments, which are assembled from shell proteins, encapsulate various cargo proteins, typically peroxidases or ferritin-like proteins, to protect cells from oxidative stress caused by peroxide. Proteins of this family are cysteine desulfurases with an additional N-terminal encapsulation targeting sequence (~200 aa) that is necessary and sufficient for compartmentalization.
Pssm-ID: 469077 [Multi-domain] Cd Length: 623 Bit Score: 429.27 E-value: 2.18e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 6 FNITKIRNDFPTLNQTLNGNPLVYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNV 85
Cdd:NF041166 225 FDVNAVRRDFPILQERVNGKPLVWFDNAATTQKPQAVIDRLSYFYEHENSNIHRAAHELAARATDAYEGAREKVRRFIGA 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 86 -NAKEIVWTKSATEALNLLAHGLQRQITGE-DTVLITPLEHHANIVPWQVLTQNTGATLSALP--------LEQNAtfni 155
Cdd:NF041166 305 pSVDEIIFVRGTTEAINLVAKSWGRQNIGAgDEIIVSHLEHHANIVPWQQLAQETGAKLRVIPvddsgqilLDEYA---- 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 156 arciDMITHtKAKVLCISQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGV 235
Cdd:NF041166 381 ----KLLNP-RTKLVSVTQVSNALGTVTPVKEIIALAHRAGAKVLVDGAQSVSHMPVDVQALDADFFVFSGHKVFGPTGI 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 236 GGLYGRYELLNALTPYQTGGEMIDTVTLEKSTYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAA 315
Cdd:NF041166 456 GVVYGKRDLLEAMPPWQGGGNMIADVTFEKTVYQPAPNRFEAGTGNIADAVGLGAALDYVERIGIENIARYEHDLLEYAT 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 316 TQLSEIDGITIysdlnnnIGT-------LSFN---YKSEhpyDLATLLDGFGIAVRSGHHCTQPLMHHLGVKGTVRASFA 385
Cdd:NF041166 536 AGLAEVPGLRL-------IGTaadkasvLSFVldgYSTE---EVGKALNQEGIAVRSGHHCAQPILRRFGVEATVRPSLA 605
|
410
....*....|....*
gi 658750212 386 FYNTHQDVDNFINAL 400
Cdd:NF041166 606 FYNTCEEVDALVAVL 620
|
|
| PRK10874 |
PRK10874 |
cysteine desulfurase CsdA; |
6-407 |
3.18e-145 |
|
cysteine desulfurase CsdA;
Pssm-ID: 182799 [Multi-domain] Cd Length: 401 Bit Score: 418.29 E-value: 3.18e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 6 FNITKIRNDFPTLNQtlngnPLVYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNV 85
Cdd:PRK10874 4 FNPAQFRAQFPALQD-----AGVYLDSAATALKPQAVIEATQQFYSLSAGNVHRSQFAAAQRLTARYEAAREQVAQLLNA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 86 N-AKEIVWTKSATEALNLLAHGLQR-QITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPLEQNATFNIARCIDMIT 163
Cdd:PRK10874 79 PdAKNIVWTRGTTESINLVAQSYARpRLQPGDEIIVSEAEHHANLVPWLMVAQQTGAKVVKLPLGADRLPDVDLLPELIT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 164 hTKAKVLCISQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYE 243
Cdd:PRK10874 159 -PRTRILALGQMSNVTGGCPDLARAITLAHQAGMVVMVDGAQGAVHFPADVQALDIDFYAFSGHKLYGPTGIGVLYGKSE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 244 LLNALTPYQTGGEMIDTVTLEKSTYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEIDG 323
Cdd:PRK10874 238 LLEAMSPWQGGGKMLTEVSFDGFTPQSAPWRFEAGTPNVAGVIGLSAALEWLADIDINQAESWSRSLATLAEDALAKLPG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 324 ITIYSDLNNNIgtLSFNYKSEHPYDLATLLDGFGIAVRSGHHCTQPLMHHLGVKGTVRASFAFYNTHQDVDNFINALKES 403
Cdd:PRK10874 318 FRSFRCQDSSL--LAFDFAGVHHSDLVTLLAEYGIALRAGQHCAQPLLAALGVTGTLRASFAPYNTQSDVDALVNAVDRA 395
|
....
gi 658750212 404 IELL 407
Cdd:PRK10874 396 LELL 399
|
|
| FeS_syn_CsdA |
TIGR03392 |
cysteine desulfurase, catalytic subunit CsdA; Members of this protein family are CsdS. This ... |
6-407 |
5.88e-135 |
|
cysteine desulfurase, catalytic subunit CsdA; Members of this protein family are CsdS. This protein, found Escherichia coli, Yersinia pestis, Photorhabdus luminescens, and related species, and related to SufS, works together with and physically interacts with CsdE (a paralog of SufE). CsdA has cysteine desulfurase activity that is enhanced by CsdE, a sulfur acceptor protein. This gene pair, although involved in FeS cluster biosynthesis, is not found next to other such genes as are its paralogs from the Suf or Isc systems. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]
Pssm-ID: 274558 [Multi-domain] Cd Length: 398 Bit Score: 392.28 E-value: 5.88e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 6 FNITKIRNDFPTLNQTLngnplVYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNV 85
Cdd:TIGR03392 1 FNPAQFRRQFPALQDAT-----VYLDSAATALKPQAVIDATQQFYRLSSGTVHRSQHQEAQSLTARYEAAREQVAQLLNA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 86 N-AKEIVWTKSATEALNLLAHGLQR-QITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPLEQNATFNIARCIDMIT 163
Cdd:TIGR03392 76 PdAENIVWTRGTTESINLVAQSYARpRLQPGDEIIVSEAEHHANLIPWLMVAQQTGAKVVKLPIGADLLPDIDQLPELLT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 164 hTKAKVLCISQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYE 243
Cdd:TIGR03392 156 -PRTRILALGQMSNVTGGCPDLARAITLAHQYGCVVVVDGAQGVVHFPADVQALDIDFYAFSGHKLYGPTGIGVLYGKTE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 244 LLNALTPYQTGGEMIDTVTLEKSTYRDAPAKFETGTPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEIDG 323
Cdd:TIGR03392 235 LLEAMPPWQGGGKMLSHVSFDGFTPQAVPWRFEAGTPNIAGVIGLSAALEWLADIDINAAESWSVSLATLAEEALAQLPG 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 324 ITIYSDLNNNIgtLSFNYKSEHPYDLATLLDGFGIAVRSGHHCTQPLMHHLGVKGTVRASFAFYNTHQDVDNFINALKES 403
Cdd:TIGR03392 315 FRSFRCQGSSL--LAFDFAGVHHSDLVTLLAEQGIALRAGQHCAQPLMAALGVSGTLRASFAPYNTQQDVDALVNAVGRA 392
|
....
gi 658750212 404 IELL 407
Cdd:TIGR03392 393 LELL 396
|
|
| am_tr_V_VC1184 |
TIGR01976 |
cysteine desulfurase family protein, VC1184 subfamily; This model describes a subfamily of ... |
6-400 |
2.63e-77 |
|
cysteine desulfurase family protein, VC1184 subfamily; This model describes a subfamily of probable pyridoxal phosphate-dependent enzymes in the aminotransferase class V family (pfam00266). The most closely related characterized proteins are active as cysteine desulfurases, selenocysteine lyases, or both; some are involved in FeS cofactor biosynthesis and are designated NifS. An active site Cys residue present in those sequences, in motifs resembling GHHC or GSAC, is not found in this family. The function of members of this family is unknown, but seems unlike to be as an aminotransferase. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273906 [Multi-domain] Cd Length: 397 Bit Score: 244.66 E-value: 2.63e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 6 FNITKIRNDFPTLNQTlngnPLVYLDSGATSQKPQSVIDATTRFynLGNANVHRGRHTLSERATEQY-EAARLKTADYFN 84
Cdd:TIGR01976 1 FDVEAVRGQFPALADG----DRVFFDNPAGTQIPQSVADAVSAA--LTRSNANRGGAYESSRRADQVvDDAREAVADLLN 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 85 VNAKEIVWTKSATEALNLLAHGLQRQITGEDTVLITPLEHHANIVPWQVLTQNTGATLSALPleqnatFNIArciDMITH 164
Cdd:TIGR01976 75 ADPPEVVFGANATSLTFLLSRAISRRWGPGDEVIVTRLDHEANISPWLQAAERAGAKVKWAR------VDEA---TGELH 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 165 T---------KAKVLCISQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTgV 235
Cdd:TIGR01976 146 PddlasllspRTRLVAVTAASNTLGSIVDLAAITELVHAAGALVVVDAVHYAPHGLIDVQATGADFLTCSAYKFFGPH-M 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 236 GGLYGRYELLNALTPYQtggemidtvtlEKSTYRDAPAKFETGTPNIAGVIGFSAAIDYLSALN--------------IE 301
Cdd:TIGR01976 225 GILWGRPELLMNLPPYK-----------LTFSYDTGPERFELGTPQYELLAGVVAAVDYLAGLGesangsrrerlvasFQ 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 302 QLQCHEQAIFNYAATQLSEIDGITIYS--DLNNNIGTLSFNYKSEHPYDLATLLDGFGIAVRSGHHCTQPLMHHLGVK-- 377
Cdd:TIGR01976 294 AIDAYENRLAEYLLVGLSDLPGVTLYGvaRLAARVPTVSFTVHGLPPQRVVRRLADQGIDAWAGHFYAVRLLRRLGLNde 373
|
410 420
....*....|....*....|....
gi 658750212 378 -GTVRASFAFYNTHQDVDNFINAL 400
Cdd:TIGR01976 374 gGVVRVGLAHYNTAEEVDRLLEAL 397
|
|
| NifS |
COG1104 |
Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino ... |
28-405 |
6.05e-50 |
|
Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino acid transport and metabolism];
Pssm-ID: 440721 [Multi-domain] Cd Length: 381 Bit Score: 172.93 E-value: 6.05e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 28 VYLDSGATSQKPQSVIDA-----TTRFynlGNANvhrGRHTLSERATEQYEAARLKTADYFNVNAKEIVWTKSATEALNL 102
Cdd:COG1104 4 IYLDNAATTPVDPEVLEAmlpylTEYF---GNPS---SLHSFGREARAALEEAREQVAALLGADPEEIIFTSGGTEANNL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 103 LAHG-LQRQITGEDTVLITPLEHHAnivpwqVLT-----QNTGATLSALPLEQNATFNIARCIDMITHTKAKVlCISQAS 176
Cdd:COG1104 78 AIKGaARAYRKKGKHIITSAIEHPA------VLEtarflEKEGFEVTYLPVDEDGRVDLEALEAALRPDTALV-SVMHAN 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 177 NALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYELlnALTPYQTGGE 256
Cdd:COG1104 151 NETGTIQPIAEIAEIAKEHGVLFHTDAVQAVGKIPVDVKELGVDLLSLSAHKIYGPKGVGALYVRKGV--RLEPLIHGGG 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 257 MidtvtlEKStYRdapakfeTGTPNIAGVIGFSAAIDyLSALNIEQLQCHEQAIFNYAATQLSE-IDGITIYSDLNN--- 332
Cdd:COG1104 229 Q------ERG-LR-------SGTENVPGIVGLGKAAE-LAAEELEEEAARLRALRDRLEEGLLAaIPGVVINGDPENrlp 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 333 NIGTLSFNY-KSEhpyDLATLLDGFGIAVRSGHHCTQ------PLMHHLGV-----KGTVRASFAFYNTHQDVDNFINAL 400
Cdd:COG1104 294 NTLNFSFPGvEGE---ALLLALDLAGIAVSSGSACSSgslepsHVLLAMGLdeelaHGSIRFSLGRFTTEEEIDRAIEAL 370
|
....*
gi 658750212 401 KESIE 405
Cdd:COG1104 371 KEIVA 375
|
|
| PLN02651 |
PLN02651 |
cysteine desulfurase |
28-394 |
1.30e-20 |
|
cysteine desulfurase
Pssm-ID: 178257 [Multi-domain] Cd Length: 364 Bit Score: 92.41 E-value: 1.30e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 28 VYLDSGATSQKPQSVIDATTRFYNLGNANVHRGRHTLSERATEQYEAARLKTADYFNVNAKEIVWTKSATEALNLLAHGL 107
Cdd:PLN02651 1 LYLDMQATTPIDPRVLDAMLPFLIEHFGNPHSRTHLYGWESEDAVEKARAQVAALIGADPKEIIFTSGATESNNLAIKGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 108 QRQITGEDT-VLITPLEHHANIVPWQVLTQNtGATLSALPLEQNATFNIARCIDMITHTKAKVlCISQASNALGNITNLA 186
Cdd:PLN02651 81 MHFYKDKKKhVITTQTEHKCVLDSCRHLQQE-GFEVTYLPVKSDGLVDLDELAAAIRPDTALV-SVMAVNNEIGVIQPVE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 187 PLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYELLNALTPYQTGGEmidtvtlEKS 266
Cdd:PLN02651 159 EIGELCREKKVLFHTDAAQAVGKIPVDVDDLGVDLMSISGHKIYGPKGVGALYVRRRPRVRLEPLMSGGG-------QER 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 267 TYRdapakfeTGTPNIAGVIGFSAAidylSALNIEQLQCHEQAIfNYAATQL-----SEIDGITI---YSDLNNNIGTLS 338
Cdd:PLN02651 232 GRR-------SGTENTPLVVGLGAA----CELAMKEMDYDEKHM-KALRERLlnglrAKLGGVRVngpRDPEKRYPGTLN 299
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 658750212 339 FNYKSEHPydlATLLDGF-GIAVRSGHHCTQP------LMHHLGVK-----GTVRASFAFYNTHQDVD 394
Cdd:PLN02651 300 LSFAYVEG---ESLLMGLkEVAVSSGSACTSAslepsyVLRALGVPeemahGSLRLGVGRFTTEEEVD 364
|
|
| PRK14012 |
PRK14012 |
IscS subfamily cysteine desulfurase; |
28-407 |
1.85e-19 |
|
IscS subfamily cysteine desulfurase;
Pssm-ID: 184450 [Multi-domain] Cd Length: 404 Bit Score: 89.23 E-value: 1.85e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 28 VYLDSGATSQKPQSVIDAT----TRFYNLGNAnvHRGRHTLSERATEQYEAARLKTADYFNVNAKEIVWTKSATEALNLL 103
Cdd:PRK14012 5 IYLDYSATTPVDPRVAEKMmpylTMDGTFGNP--ASRSHRFGWQAEEAVDIARNQIADLIGADPREIVFTSGATESDNLA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 104 AHGLQRQITGEDTVLIT-PLEHHANIVPWQVLtQNTGATLSALPLEQNATFNIARCIDMIThTKAKVLCISQASNALGNI 182
Cdd:PRK14012 83 IKGAAHFYQKKGKHIITsKTEHKAVLDTCRQL-EREGFEVTYLDPQSNGIIDLEKLEAAMR-DDTILVSIMHVNNEIGVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 183 TNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGRYELLNALTPYQTGGEMidtvt 262
Cdd:PRK14012 161 QDIAAIGEICRERGIIFHVDAAQSVGKVPIDLSKLKVDLMSFSAHKIYGPKGIGALYVRRKPRVRLEAQMHGGGH----- 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 263 lEKStyrdapakFETGTPNIAGVIGFSAAIdYLSALNIEQLQCHEQAIFNYAATQLSEIDGITIYSDLNNNIG---TLSF 339
Cdd:PRK14012 236 -ERG--------MRSGTLPTHQIVGMGEAA-RIAKEEMATENERIRALRDRLWNGIKDIEEVYLNGDLEQRVPgnlNVSF 305
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 658750212 340 NYKSEHPYDLAtLLDgfgIAVRSGHHCT----QP--LMHHLGVK-----GTVRASFAFYNTHQDVDNFINALKESIELL 407
Cdd:PRK14012 306 NYVEGESLIMA-LKD---LAVSSGSACTsaslEPsyVLRALGLNdelahSSIRFSLGRFTTEEEIDYAIELVRKSIGKL 380
|
|
| PRK02948 |
PRK02948 |
IscS subfamily cysteine desulfurase; |
27-400 |
1.15e-12 |
|
IscS subfamily cysteine desulfurase;
Pssm-ID: 179511 [Multi-domain] Cd Length: 381 Bit Score: 68.99 E-value: 1.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 27 LVYLDSGATSQKPQSVID----ATTRFYnlGNANvhrGRHTLSERATEQYEAARLKTADYFNVNAKEIVWTKSATEA--- 99
Cdd:PRK02948 1 MIYLDYAATTPMSKEALQtyqkAASQYF--GNES---SLHDIGGTASSLLQVCRKTFAEMIGGEEQGIYFTSGGTESnyl 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 100 -----LNLLAHGLQRQITgedtvliTPLEHHANIVPWQVLTQNtGATLSALPLEQNATFNIArciDMITH-TKAKVLC-I 172
Cdd:PRK02948 76 aiqslLNALPQNKKHIIT-------TPMEHASIHSYFQSLESQ-GYTVTEIPVDKSGLIRLV---DLERAiTPDTVLAsI 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 173 SQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAMHLRPNLKQLGCDFYVFSAHKMLGPTGVGGLYGR----YELLNAL 248
Cdd:PRK02948 145 QHANSEIGTIQPIAEIGALLKKYNVLFHSDCVQTFGKLPIDVFEMGIDSLSVSAHKIYGPKGVGAVYINpqvrWKPVFPG 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 249 TPYQTGgemidtvtlekstyrdapakFETGTPNIAGVIGFSAAIDYLSAlNIEQLQCHEQAIFNYAATQLSeIDGITIYS 328
Cdd:PRK02948 225 TTHEKG--------------------FRPGTVNVPGIAAFLTAAENILK-NMQEESLRFKELRSYFLEQIQ-TLPLPIEV 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 329 D------LNNNIGTLSFNYKSEHpydlaTLLD--GFGIAVRSGHHCTQPL------MHHLG-----VKGTVRASFAFYNT 389
Cdd:PRK02948 283 EghstscLPHIIGVTIKGIEGQY-----TMLEcnRRGIAISTGSACQVGKqepsktMLAIGktyeeAKQFVRFSFGQQTT 357
|
410
....*....|.
gi 658750212 390 HQDVDNFINAL 400
Cdd:PRK02948 358 KDQIDTTIHAL 368
|
|
| PLN02724 |
PLN02724 |
Molybdenum cofactor sulfurase |
2-403 |
6.65e-11 |
|
Molybdenum cofactor sulfurase
Pssm-ID: 215384 [Multi-domain] Cd Length: 805 Bit Score: 64.12 E-value: 6.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 2 PSQEFNITKIRN-DFPTLNQTlngnplVYLD-SGAT----SQKPQSVIDATTRFYnlgnANVHrGRHTLSERATEQYEAA 75
Cdd:PLN02724 15 PDGPKPIDELRAtEFARLKGV------VYLDhAGATlyseSQLEAALADFSSNVY----GNPH-SQSDSSMRSSDTIESA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 76 RLKTADYFNVNAKE--IVWTKSATEALNLLahGLQRQITGEDTVLITpLEHHANIVPWQVLTQNTGATLSALPLEQNATF 153
Cdd:PLN02724 84 RQQVLEYFNAPPSDyaCVFTSGATAALKLV--GETFPWSSESHFCYT-LENHNSVLGIREYALEKGAAAIAVDIEEAANQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 154 NIARCIDM-ITH--TKAKVLCISQASNALGNITN------------------LAPLIAAAKAVGT------LVVVDGAQG 206
Cdd:PLN02724 161 PTNSQGSVvVKSrgLQRRNTSKLQKREDDGEAYNlfafpsecnfsgakfpldLVKLIKDNQHSNFsksgrwMVLLDAAKG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 207 AMHLRPNLKQLGCDFYVFSAHKMLG-PTGVGGLYGRYELLNALT-PYQTGGEM------IDTVTLEKSTYRdapaKFETG 278
Cdd:PLN02724 241 CGTSPPDLSRYPADFVVVSFYKIFGyPTGLGALLVRRDAAKLLKkKYFGGGTVaasiadIDFVKRRERVEQ----RFEDG 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 279 TPNIAGVIGFSAAIDYLSALNIEQLQCHEQAIFNYAATQLSEI---DGITI-------YSDLNNNIG--TLSFNYK---- 342
Cdd:PLN02724 317 TISFLSIAALRHGFKLLNRLTISAIAMHTWALTHYVANSLRNLkhgNGAPVcvlygnhTFKLEFHIQgpIVTFNLKradg 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 343 SEHPY----DLATLLdgfGIAVR--------------------------SGHHC--TQPLMHHLGVkGTVRASFAFYNTH 390
Cdd:PLN02724 397 SWVGHreveKLASLS---GIQLRtgcfcnpgacakylglshkdlqanfeAGHVCwdDQDVIHGRPT-GAVRVSFGYMSTF 472
|
490
....*....|...
gi 658750212 391 QDVDNFINALKES 403
Cdd:PLN02724 473 EDCQKFIDFIISS 485
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
72-241 |
6.68e-09 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 54.70 E-value: 6.68e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 72 YEAARLKTADYFNVNAKEIVWTKSATEALNLLAHGLqrqITGEDTVLITPLEHHANI----------VPWQVLTQNTGAT 141
Cdd:cd01494 2 LEELEEKLARLLQPGNDKAVFVPSGTGANEAALLAL---LGPGDEVIVDANGHGSRYwvaaelagakPVPVPVDDAGYGG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 142 LSALPLEQNATFNIAR--CIDMITHTkakvlcisqaSNALGNITNLAPLIAAAKAvgtLVVVDGAQGAMHlRPNLKQL-- 217
Cdd:cd01494 79 LDVAILEELKAKPNVAliVITPNTTS----------GGVLVPLKEIRKIAKEYGI---LLLVDAASAGGA-SPAPGVLip 144
|
170 180
....*....|....*....|....*.
gi 658750212 218 --GCDFYVFSAHKMLGPTGVGGLYGR 241
Cdd:cd01494 145 egGADVVTFSLHKNLGGEGGGVVIVK 170
|
|
| LdcC |
COG1982 |
Arginine/lysine/ornithine decarboxylase [Amino acid transport and metabolism]; |
148-231 |
3.69e-03 |
|
Arginine/lysine/ornithine decarboxylase [Amino acid transport and metabolism];
Pssm-ID: 441585 [Multi-domain] Cd Length: 486 Bit Score: 39.32 E-value: 3.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658750212 148 EQNATFNIARCID-------MITHTKAKVLCIsQASNALGNITNLAPLIAAAKAVGTLVVVDGAQGAmHLR--PNLK--- 215
Cdd:COG1982 136 EIDNELGIIGGITpeaveeaLIEHPDAKAVLI-TNPTYYGVCYDLKAIAELAHEHGIPVLVDEAHGA-HFGfhPDLPrsa 213
|
90
....*....|....*..
gi 658750212 216 -QLGCDFYVFSAHKMLG 231
Cdd:COG1982 214 mEAGADLVVQSTHKTLG 230
|
|
| |
