|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1032 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1460.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 1 MIESIIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQ 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 81 TVRGYSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQLGPDATGVGWVYIYALTDKSGNHDLSQLRSIQ 160
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPGKYSLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 161 DWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQSV 240
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 241 SDIEKIPLGiNEQGTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVVMRFGENAQQTINGVKEKLESLKSSLPEGVE 320
Cdd:COG3696 241 EDIENIVVK-TRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 321 IVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAI 400
Cdd:COG3696 320 IVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 401 GAMTDGAIVMIENMHKHMEKTP--LTDENRWQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLA*AASA- 477
Cdd:COG3696 400 GIIVDGAVVMVENILRRLEENRaaGTPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFa 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 478 -----GLAITLVPVLMGYFIRGKVvSEKKNPLNRLLIAIYMPVLKQVMKFPKSTVVAAILVTIVGFWPVDKIGSEFIPPL 552
Cdd:COG3696 480 llgalLLSLTLVPVLASLLLRGKV-PEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPEL 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 553 DEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGRAETATDPAPLTMIETFIQLKPQEQWREGVTTESL 632
Cdd:COG3696 559 DEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSGRTKEEL 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 633 KAEFD-KLVKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVAGPELDVIQEIGQQIEQILPEVTGTASVYSERVAGGRYI 711
Cdd:COG3696 639 IAEMReALEQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQL 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 712 KVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDSPEQLSRLPVVTPSGQRIALGDVADI 791
Cdd:COG3696 719 DIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADI 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 792 RVENGPPGIKSENARLNGWTFIDIDGVDVGTYVESAKIHLANNLKLPAGYSITWAGQYEYMERAKEKLTYVLPLTLAIIV 871
Cdd:COG3696 799 EVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIF 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 872 ILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQALAELKEKAEerae 951
Cdd:COG3696 879 LLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLRE---- 954
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 952 pisddayqdALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGGMTSAVLLTLIVLPVIYSIVKKPE 1031
Cdd:COG3696 955 ---------AIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRR 1025
|
.
gi 658754660 1032 L 1032
Cdd:COG3696 1026 L 1026
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1027 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 1143.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 1 MIESIIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQ 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 81 TVRGYSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQLGPDATGVGWVYIYALTDKSGN-------HDL 153
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGArkkdggaYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 154 SQLRSIQDWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTA 233
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 234 TGYIQSVSDIEKIPLGiNEQGTPLRIGDVATVNLGPQMRRGIAELNgEGEVVGGVVVMRFGENAQQTINGVKEKLESLKS 313
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIA-TGEGVPIRIRDVARVQIGKELRTGAATEN-GKEVVLGTVFMLIGENSRTVAQAVGDKLETINK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 314 SLPEGVEIVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSL 393
Cdd:TIGR00914 319 TLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSL 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 394 GgiAIAIGAMTDGAIVMIENMHKHMEK------TPLTDENRWQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRM 467
Cdd:TIGR00914 399 G--ALDFGLIVDGAVVIVENAHRRLAEaqhhhgRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKM 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 468 FSPLA*AASAGLA------ITLVPVLMGYFIRGKvVSEKKNPLNRLLIAIYMPVLKQVMKFPKSTVVAAILVTIVGFWPV 541
Cdd:TIGR00914 477 FHPMAFTVVLALAgamilsLTFVPAAVALFIRGK-VAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIA 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 542 DKIGSEFIPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGRAETATDPAPLTMIETFIQLKPQE 621
Cdd:TIGR00914 556 SRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPES 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 622 QWREGVTT--ESLKAEFDKLVKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVAGPELDVIQEIGQQIEQILPEVTGTAS 699
Cdd:TIGR00914 636 QWPEGKKTkeDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAAD 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 700 VYSERVAGGRYIKVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDSPEQLSRLPVVTPS 779
Cdd:TIGR00914 716 VKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPL 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 780 G-----QRIALGDVADIRVENGPPGIKSENARLNGWTFIDIDGVDVGTYVESAKIHLANNLKLPAGYSITWAGQYEYMER 854
Cdd:TIGR00914 796 SedarkQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQS 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 855 AKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVY 934
Cdd:TIGR00914 876 ATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISF 955
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 935 LNQALaelkekaEERAEPisddayQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGGMTSAVL 1014
Cdd:TIGR00914 956 IRKLL-------EEGPSL------DEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATL 1022
|
1050
....*....|...
gi 658754660 1015 LTLIVLPVIYSIV 1027
Cdd:TIGR00914 1023 LTLFVLPALYRLV 1035
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1028 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 680.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 5 IIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRG 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 85 YSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQ-LGPDATGVGWVYIYALTDKSGNHDLSQLRSIQDWF 163
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPgISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 164 LKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQSVSDI 243
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 244 EKIPLGiNEQGTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSLPEGVEIVP 323
Cdd:pfam00873 241 EKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQ-KLPGANAIETADAVRAKLAELKPTFPQGVEIVV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 324 VYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAM 403
Cdd:pfam00873 319 VYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLV 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 404 TDGAIVMIENMHKHMEKTPLTdeNRwQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLA*AASAGLAI-- 481
Cdd:pfam00873 399 VDDAIVVVENIERVLEENGLK--PL-EAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLsv 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 482 ----TLVPVLMGYFIRGKVVSEKK------NPLNRLLIAIYMPVLKQVMKFPKSTVVAAILVTIVGFWPVDKIGSEFIPP 551
Cdd:pfam00873 476 lvalTLTPALCATLLKPRREPKHGgffrwfNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPE 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 552 LDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGRAEtATDPAPLTMIETFIQLKPQEQWREGVTT-- 629
Cdd:pfam00873 556 EDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAF-SGDNNGPNSGDAFISLKPWKERPGPEKSvq 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 630 ESLKAEFDKLVKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVAGPELDVIQEIGQQIEQILPEVTGTASVYSERVAGGR 709
Cdd:pfam00873 635 ALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQP 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 710 YIKVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDSPEQLSRLPVVTPSGQRIALGDVA 789
Cdd:pfam00873 715 QLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAFA 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 790 DIRVENGPPGIKsenaRLNGWTFIDIDGV----DVGTYVESAKIHLANNLKLPAGYSITWAGQYEYMERAKEKLTYVLPL 865
Cdd:pfam00873 795 KIEWGYGPPSIN----RYNGFRSIVISGNvaagDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIAL 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 866 TLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQALAELKEK 945
Cdd:pfam00873 871 ALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEGKS 950
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 946 AEEraepisddayqdALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGGMTSAVLLTLIVLPVIYS 1025
Cdd:pfam00873 951 LEE------------AILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYV 1018
|
...
gi 658754660 1026 IVK 1028
Cdd:pfam00873 1019 LFH 1021
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
17-1029 |
1.51e-122 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 399.78 E-value: 1.51e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 17 LLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYSFFGDSYVYII 96
Cdd:NF033617 12 LLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 97 FDDDTDLYWARSRVLEYLSQVASSLPDSAKP-----QLGPDATGVgwVYIyALTdkSGNHDLSQLRSIQDWFLKYELQTV 171
Cdd:NF033617 92 FRLGTDLDVALSEVQAAINAAQSLLPSEAPDppvyrKANSADTPI--MYI-GLT--SEEMPRGQLTDYAERVLAPKLSQI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 172 PGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQSVSDIEKIPLGIN 251
Cdd:NF033617 167 NGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 252 EQGTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVVMRfGENAQQTINGVKEKLESLKSSLPEGVEIVPVYDRSKLI 331
Cdd:NF033617 247 DNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQP-GANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFI 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 332 DRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTDGAIVMI 411
Cdd:NF033617 326 RASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVV 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 412 ENMHKHME--KTPLtdenrwQIVAKAASEVG-PALFFSLLIITVsFLPVFILEAQEGRMFSPLA*AASAGLAI------T 482
Cdd:NF033617 406 ENIHRHIEegESPL------EAALKGAREIGfTVIAMTLTLVAV-YLPILFMGGLTGRLFREFAVTLAGAVIIsgivalT 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 483 LVPVLMGYFIRGkvvSEKKNPLNRL-------LIAIYMPVLKQVMKFPKSTVVAAILVTIVGFWPVDKIGSEFIPPLDEG 555
Cdd:NF033617 479 LTPMMCSRLLKA---NEKPGRFARAvdrffdgLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRG 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 556 DLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGRAETATDPAPLtmieTFIQLKPQEQwREGVTTESLKAE 635
Cdd:NF033617 556 VIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGNPGDNTGF----GIINLKPWDE-RDVSAQEIIDRL 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 636 FDKLVKFPGLtNAWVMPIKTrIDMLATGIKTPVGIKVAGPELDVIQEIGQQIEQILPEVTGTASVYSERVAGGRYIKVDI 715
Cdd:NF033617 631 RPKLAKVPGM-DLFLFPLQD-LPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDI 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 716 SRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDSPEQLSRLPVVTPSGQRIALGDVADIRVEN 795
Cdd:NF033617 709 DRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERA 788
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 796 GPPGIkSENARLNGWT--FIDIDGVDVGTYVEsaKIHLANNLKLPAGYSITWAGQYEYMERAKEKLTYVLPLTLAIIVIL 873
Cdd:NF033617 789 APLSL-NHFNQFNSATlsFNLAPGVSLGEAIE--ALDQAAKELLPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLV 865
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 874 LYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQAlaelkeKAEERAEPi 953
Cdd:NF033617 866 LAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANEL------QRHQGLSR- 938
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 658754660 954 sddayQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGGMTSAVLLTLIVLPVIYSIVKK 1029
Cdd:NF033617 939 -----REAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
17-1031 |
2.84e-63 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 233.19 E-value: 2.84e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 17 LLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYSF--FGDSYVY 94
Cdd:PRK09579 15 SVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRqnFSIISIY 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 95 IIFDDDTDLYWarSRVLEYLSQVASSLP-DSAKPQLGPDAT-GVGWVYIYALTDKSGNHDLSQL--RSIQDwflkyELQT 170
Cdd:PRK09579 95 ARIGADSDRLF--TELLAKANEVKNQLPqDAEDPVLSKEAAdASALMYISFYSEEMSNPQITDYlsRVIQP-----KLAT 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 171 VPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEmaeAEYMVT---ATGYIQSVSDIEKIP 247
Cdd:PRK09579 168 LPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVK---GEYVVTsinASTELKSAEAFAAIP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 248 LGINEQgTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVVMRfGENAQQTINGVKEKLESLKSSLPEGVEIVPVYDR 327
Cdd:PRK09579 245 VKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATP-SANPLDVIKEVRAIMPELESQLPPNLKVSIAYDA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 328 SKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTDGA 407
Cdd:PRK09579 323 TLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDA 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 408 IVMIENMHKHME--KTPLtdenrwQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLA*AASAGLAI---- 481
Cdd:PRK09579 403 IVVVENIHRHIEegKSPF------DAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIIsgiv 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 482 --TLVPVLMGYFIRgkvvsEKKNP------LNRLLIAI---YMPVLKQVMKfpKSTVVAAILVTIVGFWPVDKI--GSEF 548
Cdd:PRK09579 477 alTLSPMMCALLLR-----HEENPsglahrLDRLFERLkqrYQRALHGTLN--TRPVVLVFAVIVLALIPVLLKftQSEL 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 549 IPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGRAETATDpapltmIETFIqLKPQEQwREGVT 628
Cdd:PRK09579 550 APEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGFNGVQSG------IGGFL-LKPWNE-RERTQ 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 629 TESLKAEFDKLVKFPGL-TNAWVMPiktriDMLATGIKTPVGIKVAGP-ELDVIQEIGQQIEQILPEVTGTASVYSERVA 706
Cdd:PRK09579 622 MELLPLVQAKLEEIPGLqIFGFNLP-----SLPGTGEGLPFQFVINTAnDYESLLQVAQRVKQRAQESGKFAFLDIDLAF 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 707 GGRYIKVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQ-TVEGQErYPVNLRYPQDYRDSPEQLSRLPVVTPSGQRIAL 785
Cdd:PRK09579 697 DKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRfTIDGRS-YKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPL 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 786 GDVADIRVENGPPGIKsENARLNGWTFIDIDGVDVGTYVESAKiHLANNlKLPAGYSITWAGQYEYMERAKEKLTYVLPL 865
Cdd:PRK09579 776 STLITLSDRARPRQLN-QFQQLNSAIISGFPIVSMGEAIETVQ-QIARE-EAPEGFAFDYAGASRQYVQEGSALWVTFGL 852
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 866 TLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQAlaeLKEK 945
Cdd:PRK09579 853 ALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQL---RHEQ 929
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 946 AEERAEPISDdayqdallhGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGGMTSAVLLTLIVLPVIYS 1025
Cdd:PRK09579 930 GLSRREAIEE---------AAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYT 1000
|
....*.
gi 658754660 1026 IVKKPE 1031
Cdd:PRK09579 1001 LLAKPD 1006
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1032 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1460.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 1 MIESIIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQ 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 81 TVRGYSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQLGPDATGVGWVYIYALTDKSGNHDLSQLRSIQ 160
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPGKYSLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 161 DWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQSV 240
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 241 SDIEKIPLGiNEQGTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVVMRFGENAQQTINGVKEKLESLKSSLPEGVE 320
Cdd:COG3696 241 EDIENIVVK-TRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 321 IVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAI 400
Cdd:COG3696 320 IVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 401 GAMTDGAIVMIENMHKHMEKTP--LTDENRWQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLA*AASA- 477
Cdd:COG3696 400 GIIVDGAVVMVENILRRLEENRaaGTPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFa 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 478 -----GLAITLVPVLMGYFIRGKVvSEKKNPLNRLLIAIYMPVLKQVMKFPKSTVVAAILVTIVGFWPVDKIGSEFIPPL 552
Cdd:COG3696 480 llgalLLSLTLVPVLASLLLRGKV-PEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPEL 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 553 DEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGRAETATDPAPLTMIETFIQLKPQEQWREGVTTESL 632
Cdd:COG3696 559 DEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSGRTKEEL 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 633 KAEFD-KLVKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVAGPELDVIQEIGQQIEQILPEVTGTASVYSERVAGGRYI 711
Cdd:COG3696 639 IAEMReALEQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQL 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 712 KVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDSPEQLSRLPVVTPSGQRIALGDVADI 791
Cdd:COG3696 719 DIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADI 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 792 RVENGPPGIKSENARLNGWTFIDIDGVDVGTYVESAKIHLANNLKLPAGYSITWAGQYEYMERAKEKLTYVLPLTLAIIV 871
Cdd:COG3696 799 EVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIF 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 872 ILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQALAELKEKAEerae 951
Cdd:COG3696 879 LLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLRE---- 954
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 952 pisddayqdALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGGMTSAVLLTLIVLPVIYSIVKKPE 1031
Cdd:COG3696 955 ---------AIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRR 1025
|
.
gi 658754660 1032 L 1032
Cdd:COG3696 1026 L 1026
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1027 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 1143.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 1 MIESIIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQ 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 81 TVRGYSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQLGPDATGVGWVYIYALTDKSGN-------HDL 153
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGArkkdggaYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 154 SQLRSIQDWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTA 233
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 234 TGYIQSVSDIEKIPLGiNEQGTPLRIGDVATVNLGPQMRRGIAELNgEGEVVGGVVVMRFGENAQQTINGVKEKLESLKS 313
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIA-TGEGVPIRIRDVARVQIGKELRTGAATEN-GKEVVLGTVFMLIGENSRTVAQAVGDKLETINK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 314 SLPEGVEIVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSL 393
Cdd:TIGR00914 319 TLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSL 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 394 GgiAIAIGAMTDGAIVMIENMHKHMEK------TPLTDENRWQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRM 467
Cdd:TIGR00914 399 G--ALDFGLIVDGAVVIVENAHRRLAEaqhhhgRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKM 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 468 FSPLA*AASAGLA------ITLVPVLMGYFIRGKvVSEKKNPLNRLLIAIYMPVLKQVMKFPKSTVVAAILVTIVGFWPV 541
Cdd:TIGR00914 477 FHPMAFTVVLALAgamilsLTFVPAAVALFIRGK-VAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIA 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 542 DKIGSEFIPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGRAETATDPAPLTMIETFIQLKPQE 621
Cdd:TIGR00914 556 SRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPES 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 622 QWREGVTT--ESLKAEFDKLVKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVAGPELDVIQEIGQQIEQILPEVTGTAS 699
Cdd:TIGR00914 636 QWPEGKKTkeDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAAD 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 700 VYSERVAGGRYIKVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDSPEQLSRLPVVTPS 779
Cdd:TIGR00914 716 VKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPL 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 780 G-----QRIALGDVADIRVENGPPGIKSENARLNGWTFIDIDGVDVGTYVESAKIHLANNLKLPAGYSITWAGQYEYMER 854
Cdd:TIGR00914 796 SedarkQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQS 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 855 AKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVY 934
Cdd:TIGR00914 876 ATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISF 955
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 935 LNQALaelkekaEERAEPisddayQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGGMTSAVL 1014
Cdd:TIGR00914 956 IRKLL-------EEGPSL------DEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATL 1022
|
1050
....*....|...
gi 658754660 1015 LTLIVLPVIYSIV 1027
Cdd:TIGR00914 1023 LTLFVLPALYRLV 1035
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1028 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 680.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 5 IIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRG 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 85 YSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQ-LGPDATGVGWVYIYALTDKSGNHDLSQLRSIQDWF 163
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPgISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 164 LKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQSVSDI 243
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 244 EKIPLGiNEQGTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSLPEGVEIVP 323
Cdd:pfam00873 241 EKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQ-KLPGANAIETADAVRAKLAELKPTFPQGVEIVV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 324 VYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAM 403
Cdd:pfam00873 319 VYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLV 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 404 TDGAIVMIENMHKHMEKTPLTdeNRwQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLA*AASAGLAI-- 481
Cdd:pfam00873 399 VDDAIVVVENIERVLEENGLK--PL-EAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLsv 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 482 ----TLVPVLMGYFIRGKVVSEKK------NPLNRLLIAIYMPVLKQVMKFPKSTVVAAILVTIVGFWPVDKIGSEFIPP 551
Cdd:pfam00873 476 lvalTLTPALCATLLKPRREPKHGgffrwfNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPE 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 552 LDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGRAEtATDPAPLTMIETFIQLKPQEQWREGVTT-- 629
Cdd:pfam00873 556 EDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAF-SGDNNGPNSGDAFISLKPWKERPGPEKSvq 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 630 ESLKAEFDKLVKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVAGPELDVIQEIGQQIEQILPEVTGTASVYSERVAGGR 709
Cdd:pfam00873 635 ALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQP 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 710 YIKVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDSPEQLSRLPVVTPSGQRIALGDVA 789
Cdd:pfam00873 715 QLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAFA 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 790 DIRVENGPPGIKsenaRLNGWTFIDIDGV----DVGTYVESAKIHLANNLKLPAGYSITWAGQYEYMERAKEKLTYVLPL 865
Cdd:pfam00873 795 KIEWGYGPPSIN----RYNGFRSIVISGNvaagDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIAL 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 866 TLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQALAELKEK 945
Cdd:pfam00873 871 ALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEGKS 950
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 946 AEEraepisddayqdALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGGMTSAVLLTLIVLPVIYS 1025
Cdd:pfam00873 951 LEE------------AILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYV 1018
|
...
gi 658754660 1026 IVK 1028
Cdd:pfam00873 1019 LFH 1021
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
4-1029 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 640.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 4 SIIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVR 83
Cdd:COG0841 2 NLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYIT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 84 GYSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQ----LGPDATGVGWVyiyALTdkSGNHDLSQLRSI 159
Cdd:COG0841 82 STSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPgvtkVNPSDFPVMVL---ALS--SDDLDELELSDY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 160 QDWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQS 239
Cdd:COG0841 157 AERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 240 VSDIEKIPLGINeQGTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSLPEGV 319
Cdd:COG0841 237 PEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQ-KQPGANALEVADAVRAKLEELQASLPEGV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 320 EIVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIA 399
Cdd:COG0841 315 ELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLA 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 400 IGAMTDGAIVMIENMHKHMEKtpltDENRWQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLA*AASAGL 479
Cdd:COG0841 395 IGIVVDDAIVVVENIERHMEE----GLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIAL 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 480 AI------TLVPVLMGYFIRGKVVSEKK---NPLNRL---LIAIYMPVLKQVMKFPKSTVVAAILVTIVGFWPVDKIGSE 547
Cdd:COG0841 471 LIslfvalTLTPALCARLLKPHPKGKKGrffRAFNRGfdrLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTE 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 548 FIPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGRAETATDPaplTMIETFIQLKPQEQwREgV 627
Cdd:COG0841 551 FFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSGS---NSGTIFVTLKPWDE-RD-R 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 628 TTESLKAE-FDKLVKFPGLTnawVMPIKTRIDMLATGikTPVGIKVAGPELDVIQEIGQQIEQILPEVTGTASVYSERVA 706
Cdd:COG0841 626 SADEIIARlREKLAKIPGAR---VFVFQPPAGGLGSG--APIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQL 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 707 GGRYIKVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDSPEQLSRLPVVTPSGQRIALG 786
Cdd:COG0841 701 GKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLS 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 787 DVADIRVENGPPGIKsenaRLNGWTFIDI-----DGVDVG---TYVESakihLANNLKLPAGYSITWAGQYEYMERAKEK 858
Cdd:COG0841 781 SVATIEEGTGPSSIN----RYNGQRSVTVsanlaPGVSLGealAAIEE----LAAELKLPPGVSIEFTGQAEEEQESFSS 852
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 859 LTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQA 938
Cdd:COG0841 853 LGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQL 932
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 939 LAELKEKAEeraepisddayqdALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGGMTSAVLLTLI 1018
Cdd:COG0841 933 REEGMSLRE-------------AILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLF 999
|
1050
....*....|.
gi 658754660 1019 VLPVIYSIVKK 1029
Cdd:COG0841 1000 VVPVLYVLLDR 1010
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
17-1029 |
1.51e-122 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 399.78 E-value: 1.51e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 17 LLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYSFFGDSYVYII 96
Cdd:NF033617 12 LLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 97 FDDDTDLYWARSRVLEYLSQVASSLPDSAKP-----QLGPDATGVgwVYIyALTdkSGNHDLSQLRSIQDWFLKYELQTV 171
Cdd:NF033617 92 FRLGTDLDVALSEVQAAINAAQSLLPSEAPDppvyrKANSADTPI--MYI-GLT--SEEMPRGQLTDYAERVLAPKLSQI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 172 PGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQSVSDIEKIPLGIN 251
Cdd:NF033617 167 NGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 252 EQGTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVVMRfGENAQQTINGVKEKLESLKSSLPEGVEIVPVYDRSKLI 331
Cdd:NF033617 247 DNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQP-GANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFI 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 332 DRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTDGAIVMI 411
Cdd:NF033617 326 RASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVV 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 412 ENMHKHME--KTPLtdenrwQIVAKAASEVG-PALFFSLLIITVsFLPVFILEAQEGRMFSPLA*AASAGLAI------T 482
Cdd:NF033617 406 ENIHRHIEegESPL------EAALKGAREIGfTVIAMTLTLVAV-YLPILFMGGLTGRLFREFAVTLAGAVIIsgivalT 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 483 LVPVLMGYFIRGkvvSEKKNPLNRL-------LIAIYMPVLKQVMKFPKSTVVAAILVTIVGFWPVDKIGSEFIPPLDEG 555
Cdd:NF033617 479 LTPMMCSRLLKA---NEKPGRFARAvdrffdgLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRG 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 556 DLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGRAETATDPAPLtmieTFIQLKPQEQwREGVTTESLKAE 635
Cdd:NF033617 556 VIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGNPGDNTGF----GIINLKPWDE-RDVSAQEIIDRL 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 636 FDKLVKFPGLtNAWVMPIKTrIDMLATGIKTPVGIKVAGPELDVIQEIGQQIEQILPEVTGTASVYSERVAGGRYIKVDI 715
Cdd:NF033617 631 RPKLAKVPGM-DLFLFPLQD-LPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDI 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 716 SRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDSPEQLSRLPVVTPSGQRIALGDVADIRVEN 795
Cdd:NF033617 709 DRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERA 788
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 796 GPPGIkSENARLNGWT--FIDIDGVDVGTYVEsaKIHLANNLKLPAGYSITWAGQYEYMERAKEKLTYVLPLTLAIIVIL 873
Cdd:NF033617 789 APLSL-NHFNQFNSATlsFNLAPGVSLGEAIE--ALDQAAKELLPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLV 865
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 874 LYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQAlaelkeKAEERAEPi 953
Cdd:NF033617 866 LAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANEL------QRHQGLSR- 938
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 658754660 954 sddayQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGGMTSAVLLTLIVLPVIYSIVKK 1029
Cdd:NF033617 939 -----REAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
15-1029 |
2.38e-76 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 272.37 E-value: 2.38e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 15 FVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYS-FFGDSYV 93
Cdd:TIGR00915 11 FAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSSSdSDGSMTI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 94 YIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQ-LGPDATGVGWVYIYALTDKSGNHDLSQLRSIQDWFLKYELQTVP 172
Cdd:TIGR00915 91 TLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQgVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAASNMVDPLSRLE 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 173 GVSEVAAVGgmvKQY--QVQVDPDKLRAYDIPLSLIQIALQKGNKETGAS------VVEMAEAEYMVTATGYIQSVSDIE 244
Cdd:TIGR00915 171 GVGDVQLFG---SQYamRIWLDPAKLNSYQLTPADVISAISAQNAQISAGqlgglpAVPGQQLNATIIAQTRLQTPEQFE 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 245 KIPLGINEQGTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSLPEGVEIVPV 324
Cdd:TIGR00915 248 NILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIK-LATGANALDTAKAVKAELAVLEPFFPQGMKYVYP 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 325 YDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMT 404
Cdd:TIGR00915 327 YDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAIGLLV 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 405 DGAIVMIENMHKHMEKTPLTDENRWQivaKAASEVGPALFFSLLIITVSFLPVFILEAQEG---RMFSPLA*AASAGLAI 481
Cdd:TIGR00915 407 DDAIVVVENVERVMAEEGLPPKEATR---KSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGaiyRQFSITIVSAMALSVL 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 482 ---TLVPVL---MGYFIRGKVVSEKK----NPLNRLLIAI---YMPVLKQVMKFPKSTVVAAILVTIVGFWPVDKIGSEF 548
Cdd:TIGR00915 484 valILTPALcatMLKPIEKGEHHEKKggffGWFNRMFDSSthgYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLPTSF 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 549 IPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVP--EVETVFGKVGRAETATDPaplTMIETFIQLKPQEQwREG 626
Cdd:TIGR00915 564 LPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEkaNVESVFTVNGFSFAGRGQ---NMGMAFIRLKDWEE-RTG 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 627 VTTESLKAEFDKLVKFPGLTNAWVMPIktrIDMLATGIKTPVGIKV-----AGPELDVIQEIGQQIEQILPEVTGTASVY 701
Cdd:TIGR00915 640 KENSVFAIAGRATGHFMQIKDAMVIAF---VPPAILELGNATGFDFflqdrAGLGHEALLQARNQLLGLAAQNPALTRVR 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 702 SERVAGGRYIKVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDSPEQLSRLPVVTPSGQ 781
Cdd:TIGR00915 717 PNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGE 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 782 RIALGDVADIRVENGPPGIKsenaRLNGWTFIDIDGVDVGTYVESAKIHLANNL--KLPAGYSITWAGQyEYMERAKEKL 859
Cdd:TIGR00915 797 MVPFSAFATVRWEYGSPQLE----RYNGLPSMEILGSAAPGVSTGQAMAAMEAIaqKLPPGFGFSWTGM-SYEERLSGSQ 871
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 860 TYVL-PLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNqa 938
Cdd:TIGR00915 872 APALyALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAK-- 949
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 939 laELKEKAEERAEpisddayqdALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGGMTSAVLLTLI 1018
Cdd:TIGR00915 950 --ELMAQGKSIVE---------AALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIF 1018
|
1050
....*....|.
gi 658754660 1019 VLPVIYSIVKK 1029
Cdd:TIGR00915 1019 FVPLFYVVVRR 1029
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
17-1031 |
2.84e-63 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 233.19 E-value: 2.84e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 17 LLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYSF--FGDSYVY 94
Cdd:PRK09579 15 SVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRqnFSIISIY 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 95 IIFDDDTDLYWarSRVLEYLSQVASSLP-DSAKPQLGPDAT-GVGWVYIYALTDKSGNHDLSQL--RSIQDwflkyELQT 170
Cdd:PRK09579 95 ARIGADSDRLF--TELLAKANEVKNQLPqDAEDPVLSKEAAdASALMYISFYSEEMSNPQITDYlsRVIQP-----KLAT 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 171 VPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEmaeAEYMVT---ATGYIQSVSDIEKIP 247
Cdd:PRK09579 168 LPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVK---GEYVVTsinASTELKSAEAFAAIP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 248 LGINEQgTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVVMRfGENAQQTINGVKEKLESLKSSLPEGVEIVPVYDR 327
Cdd:PRK09579 245 VKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATP-SANPLDVIKEVRAIMPELESQLPPNLKVSIAYDA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 328 SKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTDGA 407
Cdd:PRK09579 323 TLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDA 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 408 IVMIENMHKHME--KTPLtdenrwQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLA*AASAGLAI---- 481
Cdd:PRK09579 403 IVVVENIHRHIEegKSPF------DAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIIsgiv 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 482 --TLVPVLMGYFIRgkvvsEKKNP------LNRLLIAI---YMPVLKQVMKfpKSTVVAAILVTIVGFWPVDKI--GSEF 548
Cdd:PRK09579 477 alTLSPMMCALLLR-----HEENPsglahrLDRLFERLkqrYQRALHGTLN--TRPVVLVFAVIVLALIPVLLKftQSEL 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 549 IPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGRAETATDpapltmIETFIqLKPQEQwREGVT 628
Cdd:PRK09579 550 APEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGFNGVQSG------IGGFL-LKPWNE-RERTQ 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 629 TESLKAEFDKLVKFPGL-TNAWVMPiktriDMLATGIKTPVGIKVAGP-ELDVIQEIGQQIEQILPEVTGTASVYSERVA 706
Cdd:PRK09579 622 MELLPLVQAKLEEIPGLqIFGFNLP-----SLPGTGEGLPFQFVINTAnDYESLLQVAQRVKQRAQESGKFAFLDIDLAF 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 707 GGRYIKVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQ-TVEGQErYPVNLRYPQDYRDSPEQLSRLPVVTPSGQRIAL 785
Cdd:PRK09579 697 DKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRfTIDGRS-YKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPL 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 786 GDVADIRVENGPPGIKsENARLNGWTFIDIDGVDVGTYVESAKiHLANNlKLPAGYSITWAGQYEYMERAKEKLTYVLPL 865
Cdd:PRK09579 776 STLITLSDRARPRQLN-QFQQLNSAIISGFPIVSMGEAIETVQ-QIARE-EAPEGFAFDYAGASRQYVQEGSALWVTFGL 852
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 866 TLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQAlaeLKEK 945
Cdd:PRK09579 853 ALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQL---RHEQ 929
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 946 AEERAEPISDdayqdallhGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGGMTSAVLLTLIVLPVIYS 1025
Cdd:PRK09579 930 GLSRREAIEE---------AAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYT 1000
|
....*.
gi 658754660 1026 IVKKPE 1031
Cdd:PRK09579 1001 LLAKPD 1006
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
13-1024 |
9.42e-60 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 222.68 E-value: 9.42e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 13 RFFVL---------LITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVR 83
Cdd:PRK10614 2 KFFALfiyrpvatiLLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 84 GYSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDS---------AKPQLGPdatgvgwvyIYALTDKSGNHDLS 154
Cdd:PRK10614 82 SSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGmpsrptyrkANPSDAP---------IMILTLTSDTYSQG 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 155 QLRSIQDWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTAT 234
Cdd:PRK10614 153 QLYDFASTQLAQTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTN 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 235 GYIQSVSDIEKIPLGINeQGTPLRIGDVATVNLGPQMRRGiAELNGEGEVVGGVVVMRFGENAQQTINGVKEKLESLKSS 314
Cdd:PRK10614 233 DELKTAAEYQPLIIHYN-NGAAVRLGDVATVTDSVQDVRN-AGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRET 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 315 LPEGVEIVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLG 394
Cdd:PRK10614 311 IPAAIDLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLM 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 395 GIAIAIGAMTDGAIVMIENMHKHMEK--TPLtdenrwQIVAKAASEVGpalfFSLLIITVS----FLPVFILEAQEGRMF 468
Cdd:PRK10614 391 ALTIATGFVVDDAIVVLENISRHLEAgmKPL------QAALQGVREVG----FTVLSMSLSlvavFLPLLLMGGLPGRLF 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 469 SPLA*AASAGLAI------TLVPVLMGYFIRGKVVSEKKNP--LNRLLIAI---YMPVLKQVMKfpKSTVVAAILVTIVG 537
Cdd:PRK10614 461 REFAVTLSVAIGIsllvslTLTPMMCAWLLKSSKPREQKRLrgFGRMLVALqqgYGRSLKWVLN--HTRWVGVVLLGTIA 538
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 538 F--WPVDKIGSEFIPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGRAETATDpapltmiETFI 615
Cdd:PRK10614 539 LnvWLYISIPKTFFPEQDTGRLMGFIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSG-------MMFI 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 616 QLKPQEQWREgvTTESLKAEF-DKLVKFPGlTNAWVMPIKtriDMLATGIKTPVGIKVA--GPELDVIQEIGQQIEQILP 692
Cdd:PRK10614 612 TLKPLSERSE--TAQQVIDRLrVKLAKEPG-ANLFLMAVQ---DIRVGGRQSNASYQYTllSDDLAALREWEPKIRKALA 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 693 EVTGTASVYSERVAGGRYIKVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDSPEQLSR 772
Cdd:PRK10614 686 ALPELADVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEK 765
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 773 LPVVTPSGQRIALGDVADIRVENGPPGIKSENarLNGWTFIDIDGVDVGTYVE-SAKIHLA-NNLKLPAGYSITWAGQYE 850
Cdd:PRK10614 766 MFVINNEGKAIPLSYFAKWQPANAPLSVNHQG--LSAASTISFNLPTGKSLSDaSAAIERAmTQLGVPSTVRGSFAGTAQ 843
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 851 YMERAKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGlwLMYLEGFN--FSVAVGVGFIALAGVAVEIG 928
Cdd:PRK10614 844 VFQETMNSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGA--LLALELFNapFSLIALIGIMLLIGIVKKNA 921
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 929 VIMLVYLNQAlaelkekaeERAEPISDdayQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGG 1008
Cdd:PRK10614 922 IMMVDFALEA---------QRNGNLTA---QEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGG 989
|
1050
....*....|....*.
gi 658754660 1009 MTSAVLLTLIVLPVIY 1024
Cdd:PRK10614 990 LVMSQLLTLYTTPVVY 1005
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
15-1029 |
4.64e-56 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 211.69 E-value: 4.64e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 15 FVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYS-FFGDSYV 93
Cdd:PRK15127 11 FAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdSTGTVQI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 94 YIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQ-LGPDATGVGWVYIYALTDKSGNHDLSQLRSIQDWFLKYELQTVP 172
Cdd:PRK15127 91 TLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQgVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDPISRTS 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 173 GVSEVAAVGGmvkQYQVQV--DPDKLRAYDI-PLSLIQiALQKGNKET------GASVVEMAEAEYMVTATGYIQSVSDI 243
Cdd:PRK15127 171 GVGDVQLFGS---QYAMRIwmNPNELNKFQLtPVDVIN-AIKAQNAQVaagqlgGTPPVKGQQLNASIIAQTRLTSTEEF 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 244 EKIPLGINEQGTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSLPEGVEIVP 323
Cdd:PRK15127 247 GKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIK-LATGANALDTAAAIRAELAKMEPFFPSGLKIVY 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 324 VYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAM 403
Cdd:PRK15127 326 PYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLL 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 404 TDGAIVMIENMHKHMEKTPLTDEnrwQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEG---RMFSPLA*AASAGLA 480
Cdd:PRK15127 406 VDDAIVVVENVERVMAEEGLPPK---EATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGaiyRQFSITIVSAMALSV 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 481 IT---LVPVLMGYFIR-------GKVVSEKKNPLNRLLIAIYMPVLKQVMKFPKST---VVAAILVTIVGFWPVDKIGSE 547
Cdd:PRK15127 483 LValiLTPALCATMLKpiakgdhGEGKKGFFGWFNRMFEKSTHHYTDSVGNILRSTgryLVLYLIIVVGMAYLFVRLPSS 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 548 FIPPLDEGDLMYMPTTYPGISIGKARELLQQT-----DKLIRTVPEVETV--FGKVGRAETatdpaplTMIeTFIQLKPq 620
Cdd:PRK15127 563 FLPDEDQGVFLTMVQLPAGATQERTQKVLNEVtdyylTKEKNNVESVFAVngFGFAGRGQN-------TGI-AFVSLKD- 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 621 eqWREGVTTESlkaefdklvKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVA---GPELDVIQEIG---QQIEQILPEV 694
Cdd:PRK15127 634 --WADRPGEEN---------KVEAITMRATRAFSQIKDAMVFAFNLPAIVELGtatGFDFELIDQAGlghEKLTQARNQL 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 695 TGTASVYSERVAGGR--------YIKVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDS 766
Cdd:PRK15127 703 LGEAAKHPDMLVGVRpngledtpQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRML 782
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 767 PEQLSRLPVVTPSGQRIALGDVADIRVENGPPGIKsenaRLNGWTFIDIDGVDVGTYVESAKIHLANNL--KLPAGYSIT 844
Cdd:PRK15127 783 PDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLE----RYNGLPSMEILGQAAPGKSTGEAMELMEELasKLPTGVGYD 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 845 WAGQyEYMERAKEKLTyvlPLTLAIIVILLYLNFRAFSEVAII----IVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIAL 920
Cdd:PRK15127 859 WTGM-SYQERLSGNQA---PALYAISLIVVFLCLAALYESWSIpfsvMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTT 934
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 921 AGVAVEiGVIMLVYLNQALAELKEKaeeraepisddAYQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSR 1000
Cdd:PRK15127 935 IGLSAK-NAILIVEFAKDLMDKEGK-----------GLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNA 1002
|
1050 1060
....*....|....*....|....*....
gi 658754660 1001 IAAPMVGGMTSAVLLTLIVLPVIYSIVKK 1029
Cdd:PRK15127 1003 VGTGVMGGMVTATVLAIFFVPVFFVVVRR 1031
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
7-1027 |
1.10e-55 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 210.48 E-value: 1.10e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 7 RWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYS 86
Cdd:PRK09577 3 RFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 87 FFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKP---QLGPDATGVGwvYIYALTDKSGNHDLSQLRSIQDWF 163
Cdd:PRK09577 83 SAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRdgiQVEKAADNIQ--LIVSLTSDDGRLTGVELGEYASAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 164 LKYELQTVPGVSEVAAVGGmvkQYQVQV--DPDKLRAYDIPLSLIQIALQKGNK-----ETGASVV-EMAEAEYMVTATG 235
Cdd:PRK09577 161 VLQALRRVEGVGKVQFWGA---EYAMRIwpDPVKLAALGLTASDIASAVRAHNArvtigDIGRSAVpDSAPIAATVFADA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 236 YIQSVSDIEKIPLGINEQGTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSL 315
Cdd:PRK09577 238 PLKTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIK-LAPGSNAVATEKRVRATMDELSRYF 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 316 PEGVEIVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGG 395
Cdd:PRK09577 317 PPGVKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFG 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 396 IAIAIGAMTDGAIVMIENMHKHMEKTPLTDenrWQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEG---RMFS--- 469
Cdd:PRK09577 397 MVLAIGILVDDAIVVVENVERLMVEEGLSP---YDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGniyRQFAlsl 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 470 PLA*AASAGLAITLVPVLMGYFIRgKVVSEKKNP------LNRLLIAI---YMPVLKQVMKFP-KSTVVAAILVTIVGFW 539
Cdd:PRK09577 474 AVSIGFSAFLALSLTPALCATLLK-PVDGDHHEKrgffgwFNRFVARStqrYATRVGAILKRPlRWLVVYGALTAAAALL 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 540 PVdKIGSEFIPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGRAETATDPAPlTMIetFIQLKp 619
Cdd:PRK09577 553 FT-RLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYGEGPNG-GMI--FVTLK- 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 620 qeQWREGVTTES-LKAEFDKL-VKFPGLTNAWVMpiktridmlatGIKTPvgikvAGPELDV-------IQEIG------ 684
Cdd:PRK09577 628 --DWKERKAARDhVQAIVARInERFAGTPNTTVF-----------AMNSP-----ALPDLGStsgfdfrLQDRGglgyaa 689
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 685 --QQIEQILPEVTGTASVYSERVAG---GRYIKVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRY 759
Cdd:PRK09577 690 fvAAREQLLAEGAKDPALTDLMFAGtqdAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQA 769
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 760 PQDYRDSPEQLSRLPVVTPSGQRIALGDVADIRVENGPPGIksenARLNGWTFIDIDGVDVGTYVESAKIHLANNL--KL 837
Cdd:PRK09577 770 DGRHRLDPDDVKKLRVRNAQGEMVPLAAFATLHWTLGPPQL----TRYNGYPSFTINGSAAPGHSSGEAMAAIERIaaTL 845
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 838 PAGYSITWAGQyEYMERAKEKLTyvlPLTLAIIVILLYLNFRAFSE-----VAIIIVtLPMAMIGGLWLMYLEGFNFSVA 912
Cdd:PRK09577 846 PAGIGYAWSGQ-SFEERLSGAQA---PMLFALSVLVVFLALAALYEswsipFAVMLV-VPLGVIGAVLGVTLRGMPNDIY 920
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 913 VGVGFIALAGVAVEiGVIMLVYLnqalaeLKEKAEERAEPIsddayqDALLHGAGLRVRPVMMTVATIIIGLMPILYGTG 992
Cdd:PRK09577 921 FKVGLIATIGLSAK-NAILIVEV------AKDLVAQRMSLA------DAALEAARLRLRPIVMTSLAFGVGVLPLAFASG 987
|
1050 1060 1070
....*....|....*....|....*....|....*
gi 658754660 993 TGSEIMSRIAAPMVGGMTSAVLLTLIVLPVIYSIV 1027
Cdd:PRK09577 988 AASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVV 1022
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
15-1029 |
5.05e-50 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 192.74 E-value: 5.05e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 15 FVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYSF-FGDSYV 93
Cdd:PRK10555 11 FAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSgTGQASV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 94 YIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQ-LGPDATGVGWVYIYALTDKSGNHDLsqlRSIQDWF---LKYELQ 169
Cdd:PRK10555 91 TLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQgVTVRKTGDTNILTIAFVSTDGSMDK---QDIADYVasnIQDPLS 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 170 TVPGVSEVAAVGgmvKQYQVQV--DPDKLRAYDIPLSLIQIALQKGNKET------GASVVEMAEAEYMVTATGYIQSVS 241
Cdd:PRK10555 168 RVNGVGDIDAYG---SQYSMRIwlDPAKLNSFQMTTKDVTDAIESQNAQIavgqlgGTPSVDKQALNATINAQSLLQTPE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 242 DIEKIPLGINEQGTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSLPEGVEI 321
Cdd:PRK10555 245 QFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVK-LASGANEMATAKLVLNRLDELAQYFPHGLEY 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 322 VPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIG 401
Cdd:PRK10555 324 KVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIG 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 402 AMTDGAIVMIENMHKHMEKTPLTDEnrwQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEG---RMFSPLA*AASAG 478
Cdd:PRK10555 404 LLVDDAIVVVENVERIMSEEGLTPR---EATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGaiyRQFSITIVSAMVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 479 LAIT---LVPVLMGYFIR----GKVVSEK------KNPLNRLLIAIYMPVLKQVMKFPKSTVVAAILVTIVGFWPVdKIG 545
Cdd:PRK10555 481 SVLVamiLTPALCATLLKplkkGEHHGQKgffgwfNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFL-RLP 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 546 SEFIPPLDEGDLMYMPTTYPGISigkarelLQQTDKLIRTVPE---------VETVFGKVGRAETATDPAPLTMietFIQ 616
Cdd:PRK10555 560 TSFLPLEDRGMFTTSVQLPSGST-------QQQTLKVVEKVEKyyfthekdnVMSVFATVGSGPGGNGQNVARM---FIR 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 617 LKPQEQwREGVTTESLkAEFDKLVK-FPGLTNAWVMPIKTRIdmlATGIKTPVGIKV-----AGPELDVIQEIGQQIEQI 690
Cdd:PRK10555 630 LKDWDE-RDSKTGTSF-AIIERATKaFNKIKEARVIASSPPA---ISGLGSSAGFDMelqdhAGAGHDALMAARNQLLAL 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 691 LPEVTGTASVYSERVAGGRYIKVDISRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDSPEQL 770
Cdd:PRK10555 705 AAKNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDI 784
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 771 SRLPVVTPSGQRIALGDVADIRVENGPPGIKsenaRLNGWTFIDI-----DGVDVGTYVESAKIHLAnnlKLPAGYSITW 845
Cdd:PRK10555 785 NLWYVRNKDGGMVPFSAFATSRWETGSPRLE----RYNGYSAVEIvgeaaPGVSTGTAMDIMESLVK---QLPNGFGLEW 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 846 AGQyEYMER---AKEKLTYVlpLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAG 922
Cdd:PRK10555 858 TAM-SYQERlsgAQAPALYA--ISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIG 934
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 923 VAVEIGVIMLVYLNqalaELKEKAEERAEpisddayqdALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIA 1002
Cdd:PRK10555 935 LSAKNAILIVEFAN----EMNQKGHDLFE---------ATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVG 1001
|
1050 1060
....*....|....*....|....*..
gi 658754660 1003 APMVGGMTSAVLLTLIVLPVIYSIVKK 1029
Cdd:PRK10555 1002 TGVMGGMISATILAIFFVPLFFVLVRR 1028
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
13-1024 |
1.81e-48 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 187.63 E-value: 1.81e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 13 RFFVL------LITLIIAFGGLYSLQKTPVDALP--DLSDVQVIikTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRG 84
Cdd:PRK10503 14 RLFILrpvattLLMVAILLAGIIGYRALPVSALPevDYPTIQVV--TLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 85 YSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPD---------SAKPQLGPdatgvgwvyIYALTDKSGNHDLSQ 155
Cdd:PRK10503 92 QSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSdlpnppvysKVNPADPP---------IMTLAVTSTAMPMTQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 156 LRSIQDWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATG 235
Cdd:PRK10503 163 VEDMVETRVAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSAND 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 236 YIQSVSDIEKIPLGInEQGTPLRIGDVATVNLGPQMRRGIAELNGEGEVVGGVVVMRfGENAQQTINGVKEKLESLKSSL 315
Cdd:PRK10503 243 QMQSAEEYRQLIIAY-QNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQP-GANIIATADSIRQMLPQLTESL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 316 PEGVEIVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGG 395
Cdd:PRK10503 321 PKSVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 396 IAIAIGAMTDGAIVMIENMHKHMEKtpltDENRWQIVAKAASEVG---PALFFSLLIItvsFLPVFILEAQEGRMFSPLA 472
Cdd:PRK10503 401 LTIATGFVVDDAIVVIENISRYIEK----GEKPLAAALKGAGEIGftiISLTFSLIAV---LIPLLFMGDIVGRLFREFA 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 473 *AASAGLAI------TLVPVLMGYFIRGKVVSeKKNPLNRL-------LIAIYMPVLKQVMKFPKSTVVAAI--LVTIVG 537
Cdd:PRK10503 474 VTLAVAILIsavvslTLTPMMCARMLSQESLR-KQNRFSRAsermfdrVIAAYGRGLAKVLNHPWLTLSVALstLLLTVL 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 538 FWPVdkIGSEFIPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVETVFGKVGraETATDPApLTMIETFIQL 617
Cdd:PRK10503 553 LWIF--IPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVG--VDGTNPS-LNSARLQINL 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 618 KPQEQWREGVTT--ESLKAefdKLVKFPGLTnAWVMPIKT-RIDMLATgiKTPVGIKVAGPELDVIQEIGQQIEQILPEV 694
Cdd:PRK10503 628 KPLDERDDRVQKviARLQT---AVAKVPGVD-LYLQPTQDlTIDTQVS--RTQYQFTLQATSLDALSTWVPKLMEKLQQL 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 695 TGTASVYSERVAGG--RYIKVDisRDKASRFGLNIEDVQQVVSTAIGGMNVTQTVEGQERYPVNLRYPQDYRDSPEQLSR 772
Cdd:PRK10503 702 PQLSDVSSDWQDKGlvAYVNVD--RDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDT 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 773 LPVVTPSGQRIALGDVADIRVENGPPGIKS-ENARLNGWTFIDIDGVDVGTYVEsAKIHLANNLKLPAGYSITWAGQYEY 851
Cdd:PRK10503 780 IRLTSSDGGVVPLSSIATIEQRFGPLSINHlDQFPSTTISFNVPDGYSLGDAVQ-AIMDTEKTLNLPADITTQFQGSTLA 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 852 MERAkekLTYVLPLTLAIIV---ILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVaVEIG 928
Cdd:PRK10503 859 FQSA---LGSTVWLIVAAVVamyIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGI-VKKN 934
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 929 VIMLVylNQALAELKEKAEERAEPIsddaYQDALlhgagLRVRPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGG 1008
Cdd:PRK10503 935 AIMMI--DFALAAEREQGMSPRDAI----YQACL-----LRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGG 1003
|
1050
....*....|....*.
gi 658754660 1009 MTSAVLLTLIVLPVIY 1024
Cdd:PRK10503 1004 LIVSQVLTLFTTPVIY 1019
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
3-412 |
9.10e-14 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 75.91 E-value: 9.10e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 3 ESIIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTV 82
Cdd:COG0841 516 GRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESV 595
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 83 rgYSFFGDSY---------VYIIFDDDTDlywaRSR----VLEYLSQVASSLPD----SAKPQLGPDATGVGwvYIYALT 145
Cdd:COG0841 596 --FSVVGFSGggsgsnsgtIFVTLKPWDE----RDRsadeIIARLREKLAKIPGarvfVFQPPAGGLGSGAP--IEVQLQ 667
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 146 DKsgnhDLSQLRSIQDWFLKyELQTVPGVSEVAAVGGMVK-QYQVQVDPDKLRAYDIPLSLIQIALQkgNKETGASVVEM 224
Cdd:COG0841 668 GD----DLEELAAAAEKLLA-ALRQIPGLVDVRSDLQLGKpELQLDIDREKAAALGVTVADVASTLR--AALGGRYVNDF 740
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 225 AEAE-----YMVTATGYIQSVSDIEKIPLgINEQGTPLRIGDVATVnlgpQMRRGIAELNgegevvggvvvmRFGENAQQ 299
Cdd:COG0841 741 NRGGreydvRVQAPEEDRNSPEDLENLYV-RTPDGEMVPLSSVATI----EEGTGPSSIN------------RYNGQRSV 803
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 300 TING--------------VKEKLESLKssLPEGVEIVPVYDrSKLIDRAVDNLWSKLLeeLAVVAI-VCVAFLF-HLRSS 363
Cdd:COG0841 804 TVSAnlapgvslgealaaIEELAAELK--LPPGVSIEFTGQ-AEEEQESFSSLGLAFL--LALLLVyLVLAAQFeSFIQP 878
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 658754660 364 IVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTDGAIVMIE 412
Cdd:COG0841 879 LIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVD 927
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
848-1030 |
8.56e-12 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 69.50 E-value: 8.56e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 848 QYEYMERAKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEI 927
Cdd:COG1033 209 RGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDY 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 928 GVIMLVYLNQALAELKEKAEeraepisddAYQDALLHGAglrvRPVMMTVATIIIGLMPILYgtgTGSEIMSRIAAPMVG 1007
Cdd:COG1033 289 GIHLLNRYREERRKGLDKRE---------ALREALRKLG----PPVLLTSLTTAIGFLSLLF---SDIPPIRDFGIVAAI 352
|
170 180
....*....|....*....|...
gi 658754660 1008 GMTSAVLLTLIVLPVIYSIVKKP 1030
Cdd:COG1033 353 GVLLAFLTSLTLLPALLSLLPRP 375
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
674-1031 |
2.26e-09 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 61.54 E-value: 2.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 674 GPELDVIQE--IGQQIEQIlpevTGTASVyseRVAGGRYIKVDISRD--KASRFGLNIEDVqqvvSTAIGGMNVT----Q 745
Cdd:pfam00873 150 QTDLRDYADtnIKPQLSRV----PGVGDV---QLFGGSEYAMRIWLDpqKLARYGLTLTDV----VSALKEQNVNigagQ 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 746 TVEGQERYPVNLrypQDYRDSPEQLSRLPVVTPSGQRIALGDVADIRV----------ENGPPGIKSENARLNGWTFIDI 815
Cdd:pfam00873 219 LEGQGLQALIRA---QGQLQSAEDFEKIIVKNQDGSPVRLRDVATVELgselyrgfatFNGKPAVGLGVQKLPGANAIET 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 816 dgvdvgtyVESAKIHLAN-NLKLPAGYSITWA-GQYEYMERAKE--KLTYVLPLTLAIIVILLYL-NFRAfseVAIIIVT 890
Cdd:pfam00873 296 --------ADAVRAKLAElKPTFPQGVEIVVVyDTTPFIRASIEevVKTLLEAIVLVILVMFLFLqNWRA---TLIPAIA 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 891 LPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQALAELKEKAEEraepisddayqdALLHGAGLRV 970
Cdd:pfam00873 365 IPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVVDDAIVVVENIERVLEENGLKPLE------------AAYKSMGEIG 432
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 658754660 971 RPVMMTVATIIIGLMPILYGTGTGSEIMSRIAAPMVGGMTSAVLLTLIVLPVIYSIVKKPE 1031
Cdd:pfam00873 433 GALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVALTLTPALCATLLKPR 493
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
328-460 |
1.46e-08 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 58.72 E-value: 1.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 328 SKLIDRAVDNLWSKLLeeLAVVAI-VCVAFLFH-LRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTD 405
Cdd:COG1033 597 AAINESVIESQIRSLL--LALLLIfLLLLLAFRsLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVD 674
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 658754660 406 GAIVMIENMHKHMEKtpltDENRWQIVAKAASEVGPALFFSLLIITVSFLpVFIL 460
Cdd:COG1033 675 YTIHFLSRYREERRK----GGDLEEAIRRALRTTGKAILFTSLTLAAGFG-VLLF 724
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
814-1029 |
1.23e-07 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 56.02 E-value: 1.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 814 DIDGVDVGTYVESAKIHLANNLKlPAGYSITWAGQ----YEYMERAKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIV 889
Cdd:COG1033 559 DLDSEEIKALVEEVRAFLAENFP-PDGVEVTLTGSavlfAAINESVIESQIRSLLLALLLIFLLLLLAFRSLRLGLISLI 637
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 890 TLPMAMIGGLWLMYL--EGFNFSVAVgVGFIALaGVAVEIGVIMLVYLNQALAELKEKAEeraepisddAYQDAlLHGAG 967
Cdd:COG1033 638 PNLLPILLTFGLMGLlgIPLNIATAV-VASIAL-GIGVDYTIHFLSRYREERRKGGDLEE---------AIRRA-LRTTG 705
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 658754660 968 lrvRPVMMTVATIIIGlmpilYGTGTGSE--IMSRIAAPMVGGMTSAVLLTLIVLPVIYSIVKK 1029
Cdd:COG1033 706 ---KAILFTSLTLAAG-----FGVLLFSSfpPLADFGLLLALGLLVALLAALLLLPALLLLLDP 761
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
766-1034 |
2.35e-07 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 55.23 E-value: 2.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 766 SPEQLSRLPVVTPSGQRIALGDVAdiRVENGPPGIKSENArLNGW--TFIDIDGVDVGTYVESAK----------IHLAN 833
Cdd:PRK09579 236 SAEAFAAIPVKTSGDSRVLLGDVA--RVEMGAENYDSISS-FDGIpsVYIGIKATPSANPLDVIKevraimpeleSQLPP 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 834 NLKLPAGYSITwagqyEYMERAKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAV 913
Cdd:PRK09579 313 NLKVSIAYDAT-----LFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLT 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 914 GVGFIALAGVAVEIGVIMLVYLNQALaelkekaEERAEPIsddayqDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGT 993
Cdd:PRK09579 388 LLAMVLAIGLVVDDAIVVVENIHRHI-------EEGKSPF------DAALEGAREIAMPVVSMTITLAAVYAPIGFLTGL 454
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 658754660 994 GSEIMSRIAAPMVGGMTSAVLLTLIVLPVIYSIVKKPELNA 1034
Cdd:PRK09579 455 TGALFKEFALTLAGAVIISGIVALTLSPMMCALLLRHEENP 495
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
832-1030 |
1.27e-06 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 52.69 E-value: 1.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 832 ANNLKLPA--GYSITWAGQ----YEYMERAKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMI--GGLWLMY 903
Cdd:TIGR03480 238 AKDLRLDEdhGVTVRLTGEvalsDEELATVSEGATVAGLLSFVLVLVLLWLALRSPRLVFAVLVTLIVGLIltAAFATLA 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 904 LEGFNF-SVAVGVGFIalaGVAVEIGVIMLVYLnqalaelkekaeeRAEPISDDAYQDALLHGAGLRVRPVMMTVATIII 982
Cdd:TIGR03480 318 VGHLNLiSVAFAVLFI---GLGVDFAIQFSLRY-------------REERFRGGNHREALSVAARRMGAALLLAALATAA 381
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 658754660 983 GLMPILYGTGTGSEIMSRIAApmvGGMTSAVLLTLIVLPVIYSIVKKP 1030
Cdd:TIGR03480 382 GFFAFLPTDYKGVSELGIIAG---TGMFIALFVTLTVLPALLRLLRPP 426
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
836-1023 |
7.91e-06 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 49.84 E-value: 7.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 836 KLPAGYSITWAG----QYEYMERAKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSV 911
Cdd:TIGR00921 168 NPPSGKFLDVTGspaiNYDIEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYA 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658754660 912 AVGVGFIALAGVAVEIGVIMLVYLNQALAELKEKAEERAEPISDDAyqdallhgaglrvRPVMMTVATIIIGLMPILYgt 991
Cdd:TIGR00921 248 TTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTG-------------RAVLIALLTTSAGFAALAL-- 312
|
170 180 190
....*....|....*....|....*....|..
gi 658754660 992 gTGSEIMSRIAAPMVGGMTSAVLLTLIVLPVI 1023
Cdd:TIGR00921 313 -SEFPMVSEFGLGLVAGLITAYLLTLLVLPAL 343
|
|
| |
