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Conserved domains on  [gi|736694016|ref|WP_034699703|]
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ATP-binding cassette domain-containing protein [Enterococcus hirae]

Protein Classification

P-loop NTPase family protein( domain architecture ID 1562424)

P-loop NTPase (nucleoside triphosphate hydrolase) family protein contains two conserved sequence signatures, the Walker A motif (the P-loop proper) and Walker B motif which bind, respectively, the beta and gamma phosphate moieties of the bound nucleotide (typically ATP or GTP), and a Mg(2+) cation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-212 1.74e-73

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 236.09  E-value: 1.74e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFG---NEI-VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDY 75
Cdd:COG1136    4 LLELRNLTKSYGtgeGEVtALRGVSLSIEAGeFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELARL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  76 YYNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDP 155
Cdd:COG1136   84 RRRHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRP 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 736694016 156 EIIIADEPTKALDLLAANKIMTELKKIAKE--RIVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:COG1136  164 KLILADEPTGNLDSKTGEEVLELLRELNRElgTTIVMVTHDPELAARADRVIRLRDGRI 222
LolE super family cl44091
ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall ...
 382-638 4.10e-05

ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG4591:

Pssm-ID: 443648 [Multi-domain]  Cd Length: 283  Bit Score: 45.68  E-value: 4.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 382 EVAVPKRLLDLLGLKptdvIGKNLNMTglidvnpkigsneITGSKVSLNDVKVVGVIEnnpkggaitstlgrRDGKLTDG 461
Cdd:COG4591   35 EVVLGEGLAKKLGLK----VGDTITLI-------------SPDGSPKTRRFTVVGIFE--------------SGGYELDG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 462 PLLFSveAIKKMRQQAGIEKSISY-NVRAKTLDDILPIVNKLQQ--SGLQPSGDFSMIEDMLRLRKkneeqgvTISLIFF 538
Cdd:COG4591   84 SLVYV--PLETAQELLGLGDQVSGiLVKLKDGADAEAVAAALEAalPGLEVKTWRELNAALFSALK-------TEKLILL 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 539 VLsLTISIVLALFNFYI--------KKSEFRFFKFNGFSNKNILSLIISEYFILGIMSSLL-FLITFPMLSLLSQKLFSI 609
Cdd:COG4591  155 LI-LLLILLVAAFNIVNtllmsvleRTREIGILKALGASRRQIRRIFLLEGLLLGLIGGLLgLLLGLLLALLLNALLGIL 233

                        250       260
                 ....*....|....*....|....*....
gi 736694016 610 YIVSTNNLVLVLLLPFVQSIIISILSYLL 638
Cdd:COG4591  234 LPFIFALPVSLSPSDVLLALLLALLISLL 262
 
Name Accession Description Interval E-value
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-212 1.74e-73

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 236.09  E-value: 1.74e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFG---NEI-VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDY 75
Cdd:COG1136    4 LLELRNLTKSYGtgeGEVtALRGVSLSIEAGeFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELARL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  76 YYNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDP 155
Cdd:COG1136   84 RRRHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRP 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 736694016 156 EIIIADEPTKALDLLAANKIMTELKKIAKE--RIVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:COG1136  164 KLILADEPTGNLDSKTGEEVLELLRELNRElgTTIVMVTHDPELAARADRVIRLRDGRI 222
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 5-212 2.75e-68

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 221.98  E-value: 2.75e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   5 IEIK---KVFGNEI----VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYY 76
Cdd:cd03255    1 IELKnlsKTYGGGGekvqALKGVSLSIEKGeFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  77 YNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPE 156
Cdd:cd03255   81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 157 IIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:cd03255  161 IILADEPTGNLDSETGKEVMELLRELNKEAgtTIVVVTHDPELAEYADRIIELRDGKI 218
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 4-194 4.82e-54

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 183.59  E-value: 4.82e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    4 LIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGF 82
Cdd:TIGR03608   1 LKNISKKFGDKVILDDLNLTIEKGkMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASKFRREKLGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   83 IWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADE 162
Cdd:TIGR03608  81 LFQNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADE 160

                         170       180       190
                  ....*....|....*....|....*....|...
gi 736694016  163 PTKALDLLAANKIMTELKKIAKE-RIVIIVTHD 194
Cdd:TIGR03608 161 PTGSLDPKNRDEVLDLLLELNDEgKTIIIVTHD 193
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
7-220 1.98e-36

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 140.22  E-value: 1.98e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   7 IKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKElsdyyyNSIGFIWQ 85
Cdd:PRK10851   8 IKKSFGRTQVLNDISLDIPSGqMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARD------RKVGFVFQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  86 DYQLIEYLSVECNIDLVLSL----SNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIAD 161
Cdd:PRK10851  82 HYALFRHMTVFDNIAFGLTVlprrERPNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLD 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 736694016 162 EPTKALDLLAANKIMTELKKIAKER--IVIIVTHDKGLIEKDAN-VYSMEQGQLKLVGQSKQ 220
Cdd:PRK10851 162 EPFGALDAQVRKELRRWLRQLHEELkfTSVFVTHDQEEAMEVADrVVVMSQGNIEQAGTPDQ 223
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 17-164 1.51e-35

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 131.23  E-value: 1.51e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   17 LNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQLIEYLSV 95
Cdd:pfam00005   1 LKNVSLTLNPGeILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLR----KEIGYVFQDPQLFPRLTV 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 736694016   96 ECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAK----MKVAKLSGGQKQRVAIARALVKDPEIIIADEPT 164
Cdd:pfam00005  77 RENLRLGLLLKGLSKREKDARAEEALEKLGLGDLADrpvgERPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
11-198 3.65e-23

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 97.30  E-value: 3.65e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  11 FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVyfnnqsmKRFTKKelsdyyynSIGFIWQDYQL 89
Cdd:NF040873   2 YGGRPVLHGVDLTIPAGsLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV-------RRAGGA--------RVAYVPQRSEV 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  90 IEYL--SVEcniDLV--------LSLSNLNKAERkMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:NF040873  67 PDSLplTVR---DLVamgrwarrGLWRRLTRDDR-AAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLL 142

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTHDKGLI 198
Cdd:NF040873 143 LDEPTTGLDAESRERIIALLAEEHARgATVVVVTHDLELV 182
GguA NF040905
sugar ABC transporter ATP-binding protein;
31-181 5.64e-10

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 62.11  E-value: 5.64e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGM--DQNFEGDVYFNNQSMkRFtkKELSDYYYNSIGFIWQDYQLIEYLSVECNIdlvlSLSN- 107
Cdd:NF040905  32 LCGENGAGKSTLMKVLSGVypHGSYEGEILFDGEVC-RF--KDIRDSEALGIVIIHQELALIPYLSIAENI----FLGNe 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 108 ------LNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALD------LLaanKI 175
Cdd:NF040905 105 rakrgvIDWNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLILDEPTAALNeedsaaLL---DL 181


                 ....*.
gi 736694016 176 MTELKK 181
Cdd:NF040905 182 LLELKA 187
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
93-171 2.08e-08

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 57.44  E-value: 2.08e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 736694016  93 LSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLA 171
Cdd:NF033858  93 LSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLS 171
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
91-192 6.02e-07

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 52.04  E-value: 6.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  91 EYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLL 170
Cdd:NF000106  99 ESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPR 178

                         90       100
                 ....*....|....*....|..
gi 736694016 171 AANKIMTELKKIAKERIVIIVT 192
Cdd:NF000106 179 TRNEVWDEVRSMVRDGATVLLT 200
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 30-212 3.10e-06

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 47.37  E-value: 3.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    30 FIYGPSGSGKTTLLNIISGMdqnfegdvyfnnqsmkrftkkelsdYYYNSIGFIwqdyqlieylsvecnidlVLSLSNLN 109
Cdd:smart00382   6 LIVGPPGSGKTTLARALARE-------------------------LGPPGGGVI------------------YIDGEDIL 42

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   110 KAERKMKVAKVLEELGISGlakmkvaklSGGQKQRVAIARALVKDPEIIIADEPTKALD------LLAANKIMTELKKIA 183
Cdd:smart00382  43 EEVLDQLLLIIVGGKKASG---------SGELRLRLALALARKLKPDVLILDEITSLLDaeqealLLLLEELRLLLLLKS 113

                          170       180
                   ....*....|....*....|....*....
gi 736694016   184 KERIVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:smart00382 114 EKNLTVILTTNDEKDLGPALLRRRFDRRI 142
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
80-193 3.41e-06

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 50.51  E-value: 3.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:NF033858 341 VGYMSQAFSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLI 420

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 736694016 160 ADEPTKALDLLAAN---KIMTELKKiaKERIVI-IVTH 193
Cdd:NF033858 421 LDEPTSGVDPVARDmfwRLLIELSR--EDGVTIfISTH 456
LolE COG4591
ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall ...
 382-638 4.10e-05

ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443648 [Multi-domain]  Cd Length: 283  Bit Score: 45.68  E-value: 4.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 382 EVAVPKRLLDLLGLKptdvIGKNLNMTglidvnpkigsneITGSKVSLNDVKVVGVIEnnpkggaitstlgrRDGKLTDG 461
Cdd:COG4591   35 EVVLGEGLAKKLGLK----VGDTITLI-------------SPDGSPKTRRFTVVGIFE--------------SGGYELDG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 462 PLLFSveAIKKMRQQAGIEKSISY-NVRAKTLDDILPIVNKLQQ--SGLQPSGDFSMIEDMLRLRKkneeqgvTISLIFF 538
Cdd:COG4591   84 SLVYV--PLETAQELLGLGDQVSGiLVKLKDGADAEAVAAALEAalPGLEVKTWRELNAALFSALK-------TEKLILL 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 539 VLsLTISIVLALFNFYI--------KKSEFRFFKFNGFSNKNILSLIISEYFILGIMSSLL-FLITFPMLSLLSQKLFSI 609
Cdd:COG4591  155 LI-LLLILLVAAFNIVNtllmsvleRTREIGILKALGASRRQIRRIFLLEGLLLGLIGGLLgLLLGLLLALLLNALLGIL 233

                        250       260
                 ....*....|....*....|....*....
gi 736694016 610 YIVSTNNLVLVLLLPFVQSIIISILSYLL 638
Cdd:COG4591  234 LPFIFALPVSLSPSDVLLALLLALLISLL 262
GguA NF040905
sugar ABC transporter ATP-binding protein;
133-191 1.23e-04

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 45.17  E-value: 1.23e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 736694016 133 KVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIV 191
Cdd:NF040905 401 KVGNLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIV 459
FtsX pfam02687
FtsX-like permease family; This is a family of predicted permeases and hypothetical ...
 533-644 4.22e-04

FtsX-like permease family; This is a family of predicted permeases and hypothetical transmembrane proteins. Swiss:P57382 has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both Swiss:P57382 and Swiss:O54500 have been shown to require ATP. This region contains three transmembrane helices.


Pssm-ID: 460652 [Multi-domain]  Cd Length: 120  Bit Score: 40.31  E-value: 4.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  533 ISLIFFVLSLTISIVLALFNFYI--KKSEFRFFKFNGFSNKNILSLIISEYFILGIMSSLL-FLITFPMLSLLSQKLFS- 608
Cdd:pfam02687   1 ILFSLLILLLAVLIILLLLSISIseRRREIGILRALGASRKQIFKLLLLEALLIGLIGLVIgLLLGLLLAKLIAILLYSs 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 736694016  609 ----IYIVSTNNLVLVLLLPFVQSIIISILSYLLFLKTNP 644
Cdd:pfam02687  81 gislPILVPPLSILIALLLALLIALLASLLPALRIRKINP 120
 
Name Accession Description Interval E-value
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-212 1.74e-73

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 236.09  E-value: 1.74e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFG---NEI-VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDY 75
Cdd:COG1136    4 LLELRNLTKSYGtgeGEVtALRGVSLSIEAGeFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELARL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  76 YYNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDP 155
Cdd:COG1136   84 RRRHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRP 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 736694016 156 EIIIADEPTKALDLLAANKIMTELKKIAKE--RIVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:COG1136  164 KLILADEPTGNLDSKTGEEVLELLRELNRElgTTIVMVTHDPELAARADRVIRLRDGRI 222
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 5-212 2.75e-68

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 221.98  E-value: 2.75e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   5 IEIK---KVFGNEI----VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYY 76
Cdd:cd03255    1 IELKnlsKTYGGGGekvqALKGVSLSIEKGeFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  77 YNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPE 156
Cdd:cd03255   81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 157 IIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:cd03255  161 IILADEPTGNLDSETGKEVMELLRELNKEAgtTIVVVTHDPELAEYADRIIELRDGKI 218
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 4-194 4.82e-54

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 183.59  E-value: 4.82e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    4 LIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGF 82
Cdd:TIGR03608   1 LKNISKKFGDKVILDDLNLTIEKGkMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASKFRREKLGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   83 IWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADE 162
Cdd:TIGR03608  81 LFQNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADE 160

                         170       180       190
                  ....*....|....*....|....*....|...
gi 736694016  163 PTKALDLLAANKIMTELKKIAKE-RIVIIVTHD 194
Cdd:TIGR03608 161 PTGSLDPKNRDEVLDLLLELNDEgKTIIIVTHD 193
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
1-212 5.40e-54

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 184.10  E-value: 5.40e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEI-VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdYYYN 78
Cdd:COG2884    1 MIRFENVSKRYPGGReALSDVSLEIEKGeFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIP-YLRR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  79 SIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEII 158
Cdd:COG2884   80 RIGVVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELL 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 159 IADEPTKALDLLAANKIMTELKKIAKERI-VIIVTHDKGLIEK-DANVYSMEQGQL 212
Cdd:COG2884  160 LADEPTGNLDPETSWEIMELLEEINRRGTtVLIATHDLELVDRmPKRVLELEDGRL 215
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 2-194 7.96e-48

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 167.31  E-value: 7.96e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKElsdyyyNSI 80
Cdd:cd03259    1 LELKGLSKTYGSVRALDDLSLTVEPGeFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPER------RNI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIA 160
Cdd:cd03259   75 GMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLL 154

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 736694016 161 DEPTKALDLLAANKIMTELKKIAKER--IVIIVTHD 194
Cdd:cd03259  155 DEPLSALDAKLREELREELKELQRELgiTTIYVTHD 190
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 1-194 1.21e-45

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 162.53  E-value: 1.21e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVF-GNEIVLNHLSGDFQKGlNF--IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKEL----S 73
Cdd:COG3638    2 MLELRNLSKRYpGGTPALDDVSLEIERG-EFvaLIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRALrrlrR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  74 DyyynsIGFIWQDYQLIEYLSVecnIDLVL-----------SLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQK 142
Cdd:COG3638   81 R-----IGMIFQQFNLVPRLSV---LTNVLagrlgrtstwrSLLGLFPPEDRERALEALERVGLADKAYQRADQLSGGQQ 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 736694016 143 QRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHD 194
Cdd:COG3638  153 QRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDgiTVVVNLHQ 206
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-194 4.91e-44

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 161.42  E-value: 4.91e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-----LnfiyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSM------KRFtk 69
Cdd:COG3842    5 ALELENVSKRYGDVTALDDVSLSIEPGefvalL----GPSGCGKTTLLRMIAGFETPDSGRILLDGRDVtglppeKRN-- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  70 kelsdyyynsIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIAR 149
Cdd:COG3842   79 ----------VGMVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALAR 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 736694016 150 ALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER-I-VIIVTHD 194
Cdd:COG3842  149 ALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELgItFIYVTHD 195
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 12-211 2.60e-43

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 154.93  E-value: 2.60e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  12 GNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYyynsIGFIWQ--DYQ 88
Cdd:cd03225   12 GARPALDDISLTIKKGeFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRK----VGLVFQnpDDQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  89 LIEyLSVEcnIDLVLSLSNLN--KAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKA 166
Cdd:cd03225   88 FFG-PTVE--EEVAFGLENLGlpEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAG 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 736694016 167 LDLLAANKIMTELKKIAKERI-VIIVTHDKGLIEKDAN-VYSMEQGQ 211
Cdd:cd03225  165 LDPAGRRELLELLKKLKAEGKtIIIVTHDLDLLLELADrVIVLEDGK 211
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-194 5.38e-43

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 155.63  E-value: 5.38e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNE----IVLNHLSGDFQKGlNF--IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKelsd 74
Cdd:COG1116    7 ALELRGVSKRFPTGgggvTALDDVSLTVAAG-EFvaLVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPGPD---- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  75 yyynsIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKD 154
Cdd:COG1116   82 -----RGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALAND 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 736694016 155 PEIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHD 194
Cdd:COG1116  157 PEVLLMDEPFGALDALTRERLQDELLRLWQETgkTVLFVTHD 198
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 5-216 1.28e-42

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 153.64  E-value: 1.28e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   5 IEIKKV----FGNEIVLNHLSGDFQKGlNF--IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyN 78
Cdd:COG1122    1 IELENLsfsyPGGTPALDDVSLSIEKG-EFvaIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELR----R 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  79 SIGFIWQ--DYQLIEyLSVEcnIDLVLSLSNL--NKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKD 154
Cdd:COG1122   76 KVGLVFQnpDDQLFA-PTVE--EDVAFGPENLglPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAME 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 736694016 155 PEIIIADEPTKALDLLAANKIMTELKKIAKERI-VIIVTHDKGLIEKDAN-VYSMEQGQLKLVG 216
Cdd:COG1122  153 PEVLVLDEPTAGLDPRGRRELLELLKRLNKEGKtVIIVTHDLDLVAELADrVIVLDDGRIVADG 216
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
5-216 3.26e-42

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 152.53  E-value: 3.26e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   5 IEIK---KVFGNEIVLNHLSGDFQKGlnFIY---GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKelsdyYYN 78
Cdd:COG1131    1 IEVRgltKRYGDKTALDGVSLTVEPG--EIFgllGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAE-----VRR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  79 SIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEII 158
Cdd:COG1131   74 RIGYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELL 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 159 IADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTHDKGLIEKDAN-VYSMEQGQLKLVG 216
Cdd:COG1131  154 ILDEPTSGLDPEARRELWELLRELAAEgKTVLLSTHYLEEAERLCDrVAIIDKGRIVADG 213
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 2-194 5.27e-42

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 151.47  E-value: 5.27e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNE----IVLNHLSGDFQKG--LNFIyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKelsdy 75
Cdd:cd03293    1 LEVRNVSKTYGGGggavTALEDISLSVEEGefVALV-GPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPD----- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  76 yynsIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDP 155
Cdd:cd03293   75 ----RGYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDP 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 736694016 156 EIIIADEPTKALDLLAANKIMTELKKIAKERI--VIIVTHD 194
Cdd:cd03293  151 DVLLLDEPFSALDALTREQLQEELLDIWRETGktVLLVTHD 191
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 1-212 2.73e-41

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 150.34  E-value: 2.73e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFG----NEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKElsdy 75
Cdd:COG1124    1 MLEVRNLSVSYGqggrRVPVLKDVSLEVAPGESFgLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKA---- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  76 YYNSIGFIWQDYqlieYLSVecN----IDLVLS--LSNLNKAERKMKVAKVLEELGI-SGLAKMKVAKLSGGQKQRVAIA 148
Cdd:COG1124   77 FRRRVQMVFQDP----YASL--HprhtVDRILAepLRIHGLPDREERIAELLEQVGLpPSFLDRYPHQLSGGQRQRVAIA 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 736694016 149 RALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:COG1124  151 RALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERglTYLFVSHDLAVVAHLCDrVAVMQNGRI 217
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 4-194 4.05e-41

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 150.19  E-value: 4.05e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   4 LIEIKKV---FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNS 79
Cdd:COG1120    1 MLEAENLsvgYGGRPVLDDVSLSLPPGeVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELA----RR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVEcniDLVL--------SLSNLNKAERKmKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARAL 151
Cdd:COG1120   77 IAYVPQEPPAPFGLTVR---ELVAlgryphlgLFGRPSAEDRE-AVEEALERTGLEHLADRPVDELSGGERQRVLIARAL 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 736694016 152 VKDPEIIIADEPTKALDLLAANKIMTELKKIAKE--RIVIIVTHD 194
Cdd:COG1120  153 AQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARErgRTVVMVLHD 197
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 2-194 4.68e-41

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 149.31  E-value: 4.68e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFtkkelsDYYYNSI 80
Cdd:cd03300    1 IELENVSKFYGGFVALDGVSLDIKEGEFFtLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNL------PPHKRPV 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIA 160
Cdd:cd03300   75 NTVFQNYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLL 154

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 736694016 161 DEPTKALDLLAANKIMTELKKIAKER--IVIIVTHD 194
Cdd:cd03300  155 DEPLGALDLKLRKDMQLELKRLQKELgiTFVFVTHD 190
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 1-194 6.47e-41

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 152.53  E-value: 6.47e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSM------KRftkkels 73
Cdd:COG3839    3 SLELENVSKSYGGVEALKDIDLDIEDGeFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVtdlppkDR------- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  74 dyyynSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVK 153
Cdd:COG3839   76 -----NIAMVFQSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVR 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 736694016 154 DPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHD 194
Cdd:COG3839  151 EPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLgtTTIYVTHD 193
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 1-212 1.70e-40

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 147.73  E-value: 1.70e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGN----EIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDY 75
Cdd:cd03258    1 MIELKNVSKVFGDtggkVTALKDVSLSVPKGEIFgIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELRKA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  76 YYNsIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDP 155
Cdd:cd03258   81 RRR-IGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNP 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 156 EIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:cd03258  160 KVLLCDEATSALDPETTQSILALLRDINRELglTIVLITHEMEVVKRICDrVAVMEKGEV 219
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 1-212 6.17e-40

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 146.11  E-value: 6.17e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEI----VLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdY 75
Cdd:cd03257    1 LLEVKNLSVSFPTGGgsvkALDDVSFSIKKGETLgLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRK-I 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  76 YYNSIGFIWQDY------------QLIEYLSVECNIDlvlslsnlNKAERKMKVAKVLEELGIS-GLAKMKVAKLSGGQK 142
Cdd:cd03257   80 RRKEIQMVFQDPmsslnprmtigeQIAEPLRIHGKLS--------KKEARKEAVLLLLVGVGLPeEVLNRYPHELSGGQR 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 736694016 143 QRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:cd03257  152 QRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELglTLLFITHDLGVVAKIADrVAVMYAGKI 224
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 1-229 6.39e-40

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 146.54  E-value: 6.39e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNqsmkrFTKKELSDYYYNS 79
Cdd:COG4555    1 MIEVENLSKKYGKVPALKDVSFTAKDGeITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDG-----EDVRKEPREARRQ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:COG4555   76 IGVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLL 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTHDKGLIEKDA-NVYSMEQGQLKLVGQSKQHSKDDGKNN 229
Cdd:COG4555  156 LDEPTNGLDVMARRLLREILRALKKEgKTVLFSSHIMQEVEALCdRVVILHKGKVVAQGSLDELREEIGEEN 227
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 5-194 1.21e-39

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 145.79  E-value: 1.21e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   5 IEIKKVF----GNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNs 79
Cdd:cd03256    1 IEVENLSktypNGKKALKDVSLSINPGeFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQLRRQ- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNI--------DLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARAL 151
Cdd:cd03256   80 IGMIFQQFNLIERLSVLENVlsgrlgrrSTWRSLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARAL 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 736694016 152 VKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHD 194
Cdd:cd03256  160 MQQPKLILADEPVASLDPASSRQVMDLLKRINREEgiTVIVSLHQ 204
heterocyst_DevA TIGR02982
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ...
 16-213 4.46e-39

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.


Pssm-ID: 274374 [Multi-domain]  Cd Length: 220  Bit Score: 143.62  E-value: 4.46e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   16 VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNsIGFIWQDYQLIEYLS 94
Cdd:TIGR02982  20 VLFDINLEINPGeIVILTGPSGSGKTTLLTLIGGLRSVQEGSLKVLGQELHGASKKQLVQLRRR-IGYIFQAHNLLGFLT 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   95 VECNIDLVLSLS-NLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAAN 173
Cdd:TIGR02982  99 ARQNVQMALELQpNLSYQEARERARAMLEAVGLGDHLNYYPHNLSGGQKQRVAIARALVHHPKLVLADEPTAALDSKSGR 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 736694016  174 KIMTELKKIAKER--IVIIVTHDKGLIEKDANVYSMEQGQLK 213
Cdd:TIGR02982 179 DVVELMQKLAKEQgcTILMVTHDNRILDVADRILQMEDGKLL 220
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 2-194 7.55e-39

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 146.83  E-value: 7.55e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKG-----LnfiyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQsmkrftkkelsDYY 76
Cdd:COG1118    3 IEVRNISKRFGSFTLLDDVSLEIASGelvalL----GPSGSGKTTLLRIIAGLETPDSGRIVLNGR-----------DLF 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  77 YNS------IGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARA 150
Cdd:COG1118   68 TNLpprerrVGFVFQHYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARA 147

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 736694016 151 LVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE--RIVIIVTHD 194
Cdd:COG1118  148 LAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDElgGTTVFVTHD 193
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 22-211 5.24e-38

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 140.08  E-value: 5.24e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   22 GDFQkglnFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdYYYNSIGFIWQDYQLIEYLSVECNIDL 101
Cdd:TIGR02673  28 GEFL----FLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRGRQLP-LLRRRIGVVFQDFRLLPDRTVYENVAL 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  102 VLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKK 181
Cdd:TIGR02673 103 PLEVRGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLADEPTGNLDPDLSERILDLLKR 182

                         170       180       190
                  ....*....|....*....|....*....|..
gi 736694016  182 IAKERI-VIIVTHDKGLIEK-DANVYSMEQGQ 211
Cdd:TIGR02673 183 LNKRGTtVIVATHDLSLVDRvAHRVIILDDGR 214
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 1-194 1.55e-37

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 138.77  E-value: 1.55e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSmkrftKKELSDYYYNS 79
Cdd:COG4133    2 MLEAENLSCRRGERLLFSGLSFTLAAGeALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEP-----IRDAREDYRRR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAErkMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:COG4133   77 LAYLGHADGLKPELTVRENLRFWAALYGLRADR--EAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWL 154

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 736694016 160 ADEPTKALDLLAANKIMTELKK-IAKERIVIIVTHD 194
Cdd:COG4133  155 LDEPFTALDAAGVALLAELIAAhLARGGAVLLTTHQ 190
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 2-216 2.48e-37

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 138.09  E-value: 2.48e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKGLNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKelsdyYYNSIG 81
Cdd:cd03264    1 LQLENLTKRYGKKRALDGVSLTLGPGMYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQK-----LRRRIG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  82 FIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIAD 161
Cdd:cd03264   76 YLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 162 EPTKALDLLAANKIMTELKKIAKERIVIIVTHDKGLIEKDAN-VYSMEQGQLKLVG 216
Cdd:cd03264  156 EPTAGLDPEERIRFRNLLSELGEDRIVILSTHIVEDVESLCNqVAVLNKGKLVFEG 211
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 1-192 2.85e-37

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 139.36  E-value: 2.85e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    1 MLSLIEIKKVFGN-EIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYN 78
Cdd:TIGR02315   1 MLEVENLSKVYPNgKQALKNINLNINPGeFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKLRKLRRR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   79 sIGFIWQDYQLIEYLSVECNidlVL-----------SLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAI 147
Cdd:TIGR02315  81 -IGMIFQHYNLIERLTVLEN---VLhgrlgykptwrSLLGRFSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAI 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 736694016  148 ARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER-IVIIVT 192
Cdd:TIGR02315 157 ARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDgITVIIN 202
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
1-212 6.56e-37

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 140.98  E-value: 6.56e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVF----GNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDY 75
Cdd:COG1135    1 MIELENLSKTFptkgGPVTALDDVSLTIEKGEIFgIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  76 YYNsIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDP 155
Cdd:COG1135   81 RRK-IGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNP 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 736694016 156 EIIIADEPTKALDLLAANKIMTELKKIAKER---IVIIvTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:COG1135  160 KVLLCDEATSALDPETTRSILDLLKDINRELgltIVLI-THEMDVVRRICDrVAVLENGRI 219
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-194 1.44e-36

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 137.14  E-value: 1.44e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKV---FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKelsdyy 76
Cdd:COG1121    3 MMPAIELENLtvsYGGRPVLEDVSLTIPPGeFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRR------ 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  77 ynsIGFIWQDYQLIEY--LSVEcniDLVLS--------LSNLNKAERKmKVAKVLEELGISGLAKMKVAKLSGGQKQRVA 146
Cdd:COG1121   77 ---IGYVPQRAEVDWDfpITVR---DVVLMgrygrrglFRRPSRADRE-AVDEALERVGLEDLADRPIGELSGGQQQRVL 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 736694016 147 IARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERI-VIIVTHD 194
Cdd:COG1121  150 LARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRREGKtILVVTHD 198
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
7-220 1.98e-36

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 140.22  E-value: 1.98e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   7 IKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKElsdyyyNSIGFIWQ 85
Cdd:PRK10851   8 IKKSFGRTQVLNDISLDIPSGqMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARD------RKVGFVFQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  86 DYQLIEYLSVECNIDLVLSL----SNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIAD 161
Cdd:PRK10851  82 HYALFRHMTVFDNIAFGLTVlprrERPNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLD 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 736694016 162 EPTKALDLLAANKIMTELKKIAKER--IVIIVTHDKGLIEKDAN-VYSMEQGQLKLVGQSKQ 220
Cdd:PRK10851 162 EPFGALDAQVRKELRRWLRQLHEELkfTSVFVTHDQEEAMEVADrVVVMSQGNIEQAGTPDQ 223
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
2-212 3.94e-36

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 134.94  E-value: 3.94e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKElsdyYYNSI 80
Cdd:COG4619    1 LELEGLSFRVGGKPILSPVSLTLEAGeCVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPE----WRRQV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQDYQLIEYlSVECNIDLVLSLSNLNKAERKMKvaKVLEELGIS-GLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:COG4619   77 AYVPQEPALWGG-TVRDNLPFPFQLRERKFDRERAL--ELLERLGLPpDILDKPVERLSGGERQRLALIRALLLQPDVLL 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 160 ADEPTKALDllAANKIMTE--LKKIAKE--RIVIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:COG4619  154 LDEPTSALD--PENTRRVEelLREYLAEegRAVLWVSHDPEQIERVADrVLTLEAGRL 209
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 2-211 4.53e-36

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 133.47  E-value: 4.53e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKG--LNFIyGPSGSGKTTLLNIISGMDQNFEGDVYFNN---QSMKRFTKKELSDyy 76
Cdd:cd03229    1 LELKNVSKRYGQKTVLNDVSLNIEAGeiVALL-GPSGSGKSTLLRCIAGLEEPDSGSILIDGedlTDLEDELPPLRRR-- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  77 ynsIGFIWQDYQLIEYLSVECNIDLVLSlsnlnkaerkmkvakvleelgisglakmkvaklsGGQKQRVAIARALVKDPE 156
Cdd:cd03229   78 ---IGMVFQDFALFPHLTVLENIALGLS----------------------------------GGQQQRVALARALAMDPD 120

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 157 IIIADEPTKALDLLAANKIMTELKKIAKE--RIVIIVTHDKGLIEKDAN-VYSMEQGQ 211
Cdd:cd03229  121 VLLLDEPTSALDPITRREVRALLKSLQAQlgITVVLVTHDLDEAARLADrVVVLRDGK 178
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 5-194 1.04e-35

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 134.55  E-value: 1.04e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   5 IEIKKV---FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNsI 80
Cdd:cd03261    1 IELRGLtksFGGRTVLKGVDLDVRRGeILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELYRLRRR-M 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQDYQLIEYLSVECNIDLVLS-LSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:cd03261   80 GMLFQSGALFDSLTVFENVAFPLReHTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLL 159

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAKERI--VIIVTHD 194
Cdd:cd03261  160 YDEPTAGLDPIASGVIDDLIRSLKKELGltSIMVTHD 196
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 14-193 1.18e-35

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 133.94  E-value: 1.18e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  14 EIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQN---FEGDVYFNNQSMKRFTKKElsdyyynSIGFIWQDYQL 89
Cdd:cd03234   20 ARILNDVSLHVESGqVMAILGSSGSGKTTLLDAISGRVEGggtTSGQILFNGQPRKPDQFQK-------CVAYVRQDDIL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  90 IEYLSVECNI--DLVLSLSNLNKAERKMKVAKV--LEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTK 165
Cdd:cd03234   93 LPGLTVRETLtyTAILRLPRKSSDAIRKKRVEDvlLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTS 172

                        170       180
                 ....*....|....*....|....*....
gi 736694016 166 ALDLLAANKIMTELKKIAKE-RIVIIVTH 193
Cdd:cd03234  173 GLDSFTALNLVSTLSQLARRnRIVILTIH 201
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 7-216 1.43e-35

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 134.39  E-value: 1.43e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   7 IKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKElsdyyyNSIGFIWQ 85
Cdd:cd03296    8 VSKRFGDFVALDDVSLDIPSGeLVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQE------RNVGFVFQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  86 DYQLIEYLSVECNIDLVLSL----SNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIAD 161
Cdd:cd03296   82 HYALFRHMTVFDNVAFGLRVkprsERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLD 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 162 EPTKALDLLAANKIMTELKKIAKERIV--IIVTHDKG-LIEKDANVYSMEQGQLKLVG 216
Cdd:cd03296  162 EPFGALDAKVRKELRRWLRRLHDELHVttVFVTHDQEeALEVADRVVVMNKGRIEQVG 219
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 17-164 1.51e-35

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 131.23  E-value: 1.51e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   17 LNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQLIEYLSV 95
Cdd:pfam00005   1 LKNVSLTLNPGeILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLR----KEIGYVFQDPQLFPRLTV 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 736694016   96 ECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAK----MKVAKLSGGQKQRVAIARALVKDPEIIIADEPT 164
Cdd:pfam00005  77 RENLRLGLLLKGLSKREKDARAEEALEKLGLGDLADrpvgERPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 4-199 1.62e-35

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 133.30  E-value: 1.62e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   4 LIEIKKVFGNEIV-LNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdYYYNSIG 81
Cdd:cd03292    3 FINVTKTYPNGTAaLDGINISISAGeFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIP-YLRRKIG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  82 FIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIAD 161
Cdd:cd03292   82 VVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIAD 161

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 736694016 162 EPTKALDLLAANKIMTELKKIAKERIVIIV-THDKGLIE 199
Cdd:cd03292  162 EPTGNLDPDTTWEIMNLLKKINKAGTTVVVaTHAKELVD 200
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 2-194 2.01e-35

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 133.15  E-value: 2.01e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKElsdyyyNSI 80
Cdd:cd03301    1 VELENVTKRFGNVTALDDLNLDIADGEFVvLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKD------RDI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIA 160
Cdd:cd03301   75 AMVFQNYALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLM 154

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 736694016 161 DEPTKALDLLAANKIMTELKKIAKE--RIVIIVTHD 194
Cdd:cd03301  155 DEPLSNLDAKLRVQMRAELKRLQQRlgTTTIYVTHD 190
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 4-194 3.21e-35

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 133.18  E-value: 3.21e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   4 LIEIK---KVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYyNS 79
Cdd:COG1127    5 MIEVRnltKSFGDRVVLDGVSLDVPRGeILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELYELR-RR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNIDLVLS-LSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEII 158
Cdd:COG1127   84 IGMLFQGGALFDSLTVFENVAFPLReHTDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPEIL 163

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 736694016 159 IADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHD 194
Cdd:COG1127  164 LYDEPTAGLDPITSAVIDELIRELRDELglTSVVVTHD 201
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 1-211 3.67e-35

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 133.20  E-value: 3.67e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG--LNFIyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkRFTKKELsDYYYN 78
Cdd:COG1126    1 MIEIENLHKSFGDLEVLKGISLDVEKGevVVII-GPSGSGKSTLLRCINLLEEPDSGTITVDGEDL-TDSKKDI-NKLRR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  79 SIGFIWQDYQLIEYLSVECNIDL----VLslsNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKD 154
Cdd:COG1126   78 KVGMVFQQFNLFPHLTVLENVTLapikVK---KMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAME 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 155 PEIIIADEPTKALD-------LlaanKIMTELkkiAKERI-VIIVTHDKGLIEKDAN-VYSMEQGQ 211
Cdd:COG1126  155 PKVMLFDEPTSALDpelvgevL----DVMRDL---AKEGMtMVVVTHEMGFAREVADrVVFMDGGR 213
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 1-220 4.47e-35

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 139.65  E-value: 4.47e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKV-----FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGM---DQNFEGDVYFNNQSMKRFTKKE 71
Cdd:COG1123    1 MTPLLEVRDLsvrypGGDVPAVDGVSLTIAPGeTVALVGESGSGKSTLALALMGLlphGGRISGEVLLDGRDLLELSEAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  72 LSdyyyNSIGFIWQD--YQLIEyLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIAR 149
Cdd:COG1123   81 RG----RRIGMVFQDpmTQLNP-VTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAM 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 736694016 150 ALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHDKGLIEKDAN-VYSMEQGQLKLVGQSKQ 220
Cdd:COG1123  156 ALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERgtTVLLITHDLGVVAEIADrVVVMDDGRIVEDGPPEE 229
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 5-211 4.67e-35

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 130.58  E-value: 4.67e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   5 IEIKKV-F----GNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELsdyyYN 78
Cdd:cd03228    1 IEFKNVsFsypgRPKPVLKDVSLTIKPGeKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESL----RK 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  79 SIGFIWQDYQLIEyLSVECNIdlvlslsnlnkaerkmkvakvleelgisglakmkvakLSGGQKQRVAIARALVKDPEII 158
Cdd:cd03228   77 NIAYVPQDPFLFS-GTIRENI-------------------------------------LSGGQRQRIAIARALLRDPPIL 118

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 736694016 159 IADEPTKALDLLAANKIMTELKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQ 211
Cdd:cd03228  119 ILDEATSALDPETEALILEALRALAKGKTVIVIAHRLSTIRDADRIIVLDDGR 171
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 20-212 5.34e-35

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 131.65  E-value: 5.34e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  20 LSGDFQKGLNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQDYQLIEYLSVECNI 99
Cdd:cd03297   17 IDFDLNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKKINLPPQQRKIGLVFQQYALFPHLNVRENL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 100 dlVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTEL 179
Cdd:cd03297   97 --AFGLKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPEL 174

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 736694016 180 KKIAKE--RIVIIVTHDKGLIEKDA-NVYSMEQGQL 212
Cdd:cd03297  175 KQIKKNlnIPVIFVTHDLSEAEYLAdRIVVMEDGRL 210
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 33-212 3.62e-34

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 136.96  E-value: 3.62e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYyNSIGFIWQD--YQLIEYLSVECNIDLVLSLSN-LN 109
Cdd:COG1123  298 GESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSLRELR-RRVQMVFQDpySSLNPRMTVGDIIAEPLRLHGlLS 376

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 110 KAERKMKVAKVLEELGIS-GLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERI- 187
Cdd:COG1123  377 RAERRERVAELLERVGLPpDLADRYPHELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGl 456

                        170       180
                 ....*....|....*....|....*..
gi 736694016 188 -VIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:COG1123  457 tYLFISHDLAVVRYIADrVAVMYDGRI 483
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 6-220 5.13e-34

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 130.84  E-value: 5.13e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   6 EIKKVFGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIW 84
Cdd:cd03294   29 EILKKTGQTVGVNDVSLDVREGEIFvIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRELRRKKISMVF 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  85 QDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPT 164
Cdd:cd03294  109 QSFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAF 188

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 736694016 165 KALDLLAANKIMTELKKIAKE--RIVIIVTHDkgLIE--KDAN-VYSMEQGQLKLVGQSKQ 220
Cdd:cd03294  189 SALDPLIRREMQDELLRLQAElqKTIVFITHD--LDEalRLGDrIAIMKDGRLVQVGTPEE 247
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 2-212 5.39e-34

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 127.51  E-value: 5.39e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKG--LNFIyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKelsdyYYNS 79
Cdd:cd03230    1 IEVRNLSKRYGKKTALDDISLTVEKGeiYGLL-GPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEE-----VKRR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNIdlvlslsnlnkaerkmkvakvleelgisglakmkvaKLSGGQKQRVAIARALVKDPEIII 159
Cdd:cd03230   75 IGYLPEEPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHDPELLI 118

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:cd03230  119 LDEPTSGLDPESRREFWELLRELKKEgKTILLSSHILEEAERLCDrVAILNNGRI 173
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 2-212 5.89e-34

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 128.80  E-value: 5.89e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkrFTKKELSDYYYNSI 80
Cdd:cd03262    1 IEIKNLHKSFGDFHVLKGIDLTVKKGeVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKL--TDDKKNINELRQKV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQDYQLIEYLSVECNIDLVL-SLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:cd03262   79 GMVFQQFNLFPHLTVLENITLAPiKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVML 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAKERI-VIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:cd03262  159 FDEPTSALDPELVGEVLDVMKDLAEEGMtMVVVTHEMGFAREVADrVIFMDDGRI 213
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 31-194 2.36e-33

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 127.84  E-value: 2.36e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKElsdyyyNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNK 110
Cdd:cd03299   30 ILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEK------RDISYVPQNYALFPHMTVYKNIAYGLKKRKVDK 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 111 AERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IV 188
Cdd:cd03299  104 KEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKLREELKKIRKEFgvTV 183


                 ....*.
gi 736694016 189 IIVTHD 194
Cdd:cd03299  184 LHVTHD 189
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
1-194 1.24e-32

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 125.64  E-value: 1.24e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEivlnHLSGDFQ--KG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkrfTKKELSDyyy 77
Cdd:COG3840    1 MLRLDDLTYRYGDF----PLRFDLTiaAGeRVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDL---TALPPAE--- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  78 NSIGFIWQDYQLIEYLSVECNIDLVLSLS-NLNKAERKmKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPE 156
Cdd:COG3840   71 RPVSMLFQENNLFPHLTVAQNIGLGLRPGlKLTAEQRA-QVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRP 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 736694016 157 IIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHD 194
Cdd:COG3840  150 ILLLDEPFSALDPALRQEMLDLVDELCRERglTVLMVTHD 189
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 16-226 1.40e-32

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 132.57  E-value: 1.40e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  16 VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELsdyyYNSIGFIWQDYQLIeYLS 94
Cdd:COG4988  352 ALDGLSLTIPPGeRVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASW----RRQIAWVPQNPYLF-AGT 426

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  95 VECNIDL---VLSLSNLNKAERKMKVAKVLEELGiSGLAkMKV----AKLSGGQKQRVAIARALVKDPEIIIADEPTKAL 167
Cdd:COG4988  427 IRENLRLgrpDASDEELEAALEAAGLDEFVAALP-DGLD-TPLgeggRGLSGGQAQRLALARALLRDAPLLLLDEPTAHL 504

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 736694016 168 DLLAANKIMTELKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVGQSKQHSKDDG 226
Cdd:COG4988  505 DAETEAEILQALRRLAKGRTVILITHRLALLAQADRILVLDDGRIVEQGTHEELLAKNG 563
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 22-216 1.44e-32

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 129.08  E-value: 1.44e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   22 GDFQKGLNF---------IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQDYQLIEY 92
Cdd:TIGR02142  10 GDFSLDADFtlpgqgvtaIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKGIFLPPEKRRIGYVFQEARLFPH 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   93 LSVECNidLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAA 172
Cdd:TIGR02142  90 LSVRGN--LRYGMKRARPSERRISFERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRK 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 736694016  173 NKIMTELKKIAKE-RI-VIIVTHDKGLIEKDAN-VYSMEQGQLKLVG 216
Cdd:TIGR02142 168 YEILPYLERLHAEfGIpILYVSHSLQEVLRLADrVVVLEDGRVAAAG 214
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 11-194 1.48e-32

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 123.70  E-value: 1.48e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  11 FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYyynsIGFIWQdyql 89
Cdd:cd03214    9 YGGRTVLDDLSLSIEAGeIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARK----IAYVPQ---- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  90 ieylsvecnidlvlslsnlnkaerkmkvakVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDL 169
Cdd:cd03214   81 ------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDI 130

                        170       180
                 ....*....|....*....|....*..
gi 736694016 170 LAANKIMTELKKIAKER--IVIIVTHD 194
Cdd:cd03214  131 AHQIELLELLRRLARERgkTVVMVLHD 157
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 11-200 1.56e-32

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 124.95  E-value: 1.56e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  11 FGNEIVLNHLSGDFQKGlNF--IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKelsdyyynsIGFIWQDYQ 88
Cdd:cd03235    9 YGGHPVLEDVSFEVKPG-EFlaIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKR---------IGYVPQRRS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  89 lIEY---LSVEcniDLVLS--------LSNLNKAERKmKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEI 157
Cdd:cd03235   79 -IDRdfpISVR---DVVLMglyghkglFRRLSKADKA-KVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDL 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 736694016 158 IIADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTHDKGLIEK 200
Cdd:cd03235  154 LLLDEPFAGVDPKTQEDIYELLRELRREgMTILVVTHDLGLVLE 197
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 31-194 1.71e-32

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 128.68  E-value: 1.71e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQ-----SMKRFTKKELsdyyyNSIGFIWQDYQLIEYLSVECNidLVLSL 105
Cdd:COG4148   30 LFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEvlqdsARGIFLPPHR-----RRIGYVFQEARLFPHLSVRGN--LLYGR 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 106 SNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE 185
Cdd:COG4148  103 KRAPRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEILPYLERLRDE 182

                        170
                 ....*....|.
gi 736694016 186 -RI-VIIVTHD 194
Cdd:COG4148  183 lDIpILYVSHS 193
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 33-198 3.91e-32

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 126.71  E-value: 3.91e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQN---FEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQD------------YQLIEylsvec 97
Cdd:COG0444   38 GESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLLKLSEKELRKIRGREIQMIFQDpmtslnpvmtvgDQIAE------ 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  98 nidLVLSLSNLNKAERKMKVAKVLEELGISglAKMKVAK-----LSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAA 172
Cdd:COG0444  112 ---PLRIHGGLSKAEARERAIELLERVGLP--DPERRLDrypheLSGGMRQRVMIARALALEPKLLIADEPTTALDVTIQ 186

                        170       180
                 ....*....|....*....|....*...
gi 736694016 173 NKIMTELKKIAKERI--VIIVTHDKGLI 198
Cdd:COG0444  187 AQILNLLKDLQRELGlaILFITHDLGVV 214
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 33-233 5.47e-32

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 132.27  E-value: 5.47e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELsdyyYNSIGFIWQDYQLIeYLSVECNIDLVLSLSNLNKAE 112
Cdd:COG2274  508 GRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASL----RRQIGVVLQDVFLF-SGTIRENITLGDPDATDEEII 582

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 113 RKMKVAKVLEElgISGLAK---MKV----AKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE 185
Cdd:COG2274  583 EAARLAGLHDF--IEALPMgydTVVgeggSNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLKG 660

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 736694016 186 RIVIIVTHDKGLIeKDAN-VYSMEQGQLKLVGQSKQHSKDDGKNNRLNK 233
Cdd:COG2274  661 RTVIIIAHRLSTI-RLADrIIVLDKGRIVEDGTHEELLARKGLYAELVQ 708
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 3-211 8.25e-32

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 120.81  E-value: 8.25e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   3 SLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIG 81
Cdd:cd00267    1 EIENLSFRYGGRTALDNVSLTLKAGeIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELR----RRIG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  82 FIWQdyqlieylsvecnidlvlslsnlnkaerkmkvakvleelgisglakmkvakLSGGQKQRVAIARALVKDPEIIIAD 161
Cdd:cd00267   77 YVPQ---------------------------------------------------LSGGQRQRVALARALLLNPDLLLLD 105

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 736694016 162 EPTKALDLLAANKIMTELKKIAKE-RIVIIVTHDKGLIEKDAN-VYSMEQGQ 211
Cdd:cd00267  106 EPTSGLDPASRERLLELLRELAEEgRTVIIVTHDPELAELAADrVIVLKDGK 157
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 7-194 9.25e-32

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 123.56  E-value: 9.25e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   7 IKKVFGN-EIVLNHLSGDFQKG--LNFIyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFI 83
Cdd:cd03295    6 VTKRYGGgKKAVNNLNLEIAKGefLVLI-GPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVELR----RKIGYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  84 WQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLE--ELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIAD 161
Cdd:cd03295   81 IQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLAlvGLDPAEFADRYPHELSGGQQQRVGVARALAADPPLLLMD 160

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 736694016 162 EPTKALDLLAANKIMTELKKIAKE--RIVIIVTHD 194
Cdd:cd03295  161 EPFGALDPITRDQLQEEFKRLQQElgKTIVFVTHD 195
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 5-212 5.84e-31

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 120.29  E-value: 5.84e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   5 IEIKKVFGNEIVLN-HLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkrfTKKELSDyyyNSIGF 82
Cdd:cd03298    1 VRLDKIRFSYGEQPmHFDLTFAQGeITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDV---TAAPPAD---RPVSM 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  83 IWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADE 162
Cdd:cd03298   75 LFQENNLFAHLTVEQNVGLGLSPGLKLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDE 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 736694016 163 PTKALDLLAANKIMTELKKIAKER--IVIIVTHDKGLIEK-DANVYSMEQGQL 212
Cdd:cd03298  155 PFAALDPALRAEMLDLVLDLHAETkmTVLMVTHQPEDAKRlAQRVVFLDNGRI 207
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 31-195 7.07e-31

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 123.37  E-value: 7.07e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKkelsdyYYNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNK 110
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPP------HLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  111 AERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IV 188
Cdd:TIGR01187  75 AEIKPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLgiTF 154


                  ....*..
gi 736694016  189 IIVTHDK 195
Cdd:TIGR01187 155 VFVTHDQ 161
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
16-213 7.63e-31

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 120.69  E-value: 7.63e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  16 VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQDYQLIEYLS 94
Cdd:PRK11629  24 VLHNVSFSIGEGeMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDFT 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  95 VECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANK 174
Cdd:PRK11629 104 ALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADS 183

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 736694016 175 IMTELKKIAKER--IVIIVTHDKGLIEKDANVYSMEQGQLK 213
Cdd:PRK11629 184 IFQLLGELNRLQgtAFLVVTHDLQLAKRMSRQLEMRDGRLT 224
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 31-212 2.01e-30

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 119.46  E-value: 2.01e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNK 110
Cdd:COG4181   43 IVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARARLRARHVGFVFQSFQLLPTLTALENVMLPLELAGRRD 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 111 AERKmkVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IV 188
Cdd:COG4181  123 ARAR--ARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERgtTL 200

                        170       180
                 ....*....|....*....|....
gi 736694016 189 IIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:COG4181  201 VLVTHDPALAARCDRVLRLRAGRL 224
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 12-226 4.04e-29

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 122.18  E-value: 4.04e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  12 GNEIVLNHLSGDFQKG--LnFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYyynsIGFIWQDYQL 89
Cdd:COG4987  346 AGRPVLDGLSLTLPPGerV-AIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRRR----IAVVPQRPHL 420

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  90 IeYLSVECNidlvLSLSNLNKAERKMkvAKVLEELGISGLAK-------MKV----AKLSGGQKQRVAIARALVKDPEII 158
Cdd:COG4987  421 F-DTTLREN----LRLARPDATDEEL--WAALERVGLGDWLAalpdgldTWLgeggRRLSGGERRRLALARALLRDAPIL 493

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 159 IADEPTKALDLLAANKIMTELKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVGQSKQHSKDDG 226
Cdd:COG4987  494 LLDEPTEGLDAATEQALLADLLEALAGRTVLLITHRLAGLERMDRILVLEDGRIVEQGTHEELLAQNG 561
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 2-194 4.67e-29

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 115.36  E-value: 4.67e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKG--LNFIyGPSGSGKTTLLNIISGMDQNF-----EGDVYFNNQSmkRFTKKELSD 74
Cdd:cd03260    1 IELRDLNVYYGDKHALKDISLDIPKGeiTALI-GPSGCGKSTLLRLLNRLNDLIpgapdEGEVLLDGKD--IYDLDVDVL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  75 YYYNSIGFIWQDYQLIEyLSVECNIDLVLSLSN-LNKAERKMKVAKVLEELGISGLAK--MKVAKLSGGQKQRVAIARAL 151
Cdd:cd03260   78 ELRRRVGMVFQKPNPFP-GSIYDNVAYGLRLHGiKLKEELDERVEEALRKAALWDEVKdrLHALGLSGGQQQRLCLARAL 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 736694016 152 VKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIVTHD 194
Cdd:cd03260  157 ANEPEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIVTHN 199
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
3-195 4.75e-29

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 118.98  E-value: 4.75e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   3 SLIEIKKVFGNEIVLNHLSGDFQKGlNFIY--GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKElsdyyyNSI 80
Cdd:PRK11000   5 TLRNVTKAYGDVVISKDINLDIHEG-EFVVfvGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAE------RGV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIA 160
Cdd:PRK11000  78 GMVFQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLL 157

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 736694016 161 DEPTKALDLLAANKIMTELKKIAK--ERIVIIVTHDK 195
Cdd:PRK11000 158 DEPLSNLDAALRVQMRIEISRLHKrlGRTMIYVTHDQ 194
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 16-193 5.18e-29

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 114.19  E-value: 5.18e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  16 VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISG--MDQNFEGDVYFNNQSMKRFTkkelsdyYYNSIGFIWQDYQLIEY 92
Cdd:cd03213   24 LLKNVSGKAKPGeLTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPLDKRS-------FRKIIGYVPQDDILHPT 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  93 LSVEcnidlvlslsnlnkaerkmkvakvlEELGISglAKMKvaKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAA 172
Cdd:cd03213   97 LTVR-------------------------ETLMFA--AKLR--GLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSA 147

                        170       180
                 ....*....|....*....|..
gi 736694016 173 NKIMTELKKIAKE-RIVIIVTH 193
Cdd:cd03213  148 LQVMSLLRRLADTgRTIICSIH 169
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 2-223 8.36e-29

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 114.52  E-value: 8.36e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNE--IVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKElsdyyYN 78
Cdd:cd03263    1 LQIRNLTKTYKKGtkPAVDDLSLNVYKGEIFgLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAA-----RQ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  79 SIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEII 158
Cdd:cd03263   76 SLGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVL 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 159 IADEPTKALDLLAANKIMTELKKIAKERIVIIVTHDkgLIEKDA---NVYSMEQGQLKLVGqSKQHSK 223
Cdd:cd03263  156 LLDEPTSGLDPASRRAIWDLILEVRKGRSIILTTHS--MDEAEAlcdRIAIMSDGKLRCIG-SPQELK 220
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
21-194 2.43e-28

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 114.19  E-value: 2.43e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  21 SGDFqkglNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQ-----SMKRftkkelsdyyynsiGFIWQDYQLIEYLSV 95
Cdd:COG4525   32 SGEF----VVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVpvtgpGADR--------------GVVFQKDALLPWLNV 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  96 ECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKI 175
Cdd:COG4525   94 LDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLLMDEPFGALDALTREQM 173

                        170       180
                 ....*....|....*....|.
gi 736694016 176 MTELKKIAKE--RIVIIVTHD 194
Cdd:COG4525  174 QELLLDVWQRtgKGVFLITHS 194
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
31-194 3.75e-28

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 119.83  E-value: 3.75e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNK 110
Cdd:PRK10535  39 IVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLER 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 111 AERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKI-AKERIVI 189
Cdd:PRK10535 119 KQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLrDRGHTVI 198


                 ....*
gi 736694016 190 IVTHD 194
Cdd:PRK10535 199 IVTHD 203
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 33-194 9.47e-28

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 111.79  E-value: 9.47e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELsdyyynsigFIWQDYQLIEYLSVECNIDLVLS--LSNLNK 110
Cdd:TIGR01184  18 GHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDRM---------VVFQNYSLLPWLTVRENIALAVDrvLPDLSK 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  111 AERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IV 188
Cdd:TIGR01184  89 SERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEELMQIWEEHrvTV 168


                  ....*.
gi 736694016  189 IIVTHD 194
Cdd:TIGR01184 169 LMVTHD 174
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 1-193 1.61e-27

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 114.13  E-value: 1.61e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVF---GNEIV-LNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDY 75
Cdd:PRK11153   1 MIELKNISKVFpqgGRTIHaLNNVSLHIPAGEIFgVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRKA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  76 YyNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDP 155
Cdd:PRK11153  81 R-RQIGMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNP 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 736694016 156 EIIIADEPTKALDLLAANKIMTELKKIAKE---RIVIIvTH 193
Cdd:PRK11153 160 KVLLCDEATSALDPATTRSILELLKDINRElglTIVLI-TH 199
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 33-213 6.74e-27

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 109.10  E-value: 6.74e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAE 112
Cdd:PRK10584  43 GESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKLRAKHVGFVFQSFMLIPTLNALENVELPALLRGESSRQ 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 113 RKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVII 190
Cdd:PRK10584 123 SRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHgtTLIL 202

                        170       180
                 ....*....|....*....|...
gi 736694016 191 VTHDKGLIEKDANVYSMEQGQLK 213
Cdd:PRK10584 203 VTHDLQLAARCDRRLRLVNGQLQ 225
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 2-192 1.04e-26

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 108.78  E-value: 1.04e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKG-----LnfiyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkrfTKKELSDYY 76
Cdd:cd03218    1 LRAENLSKRYGKRKVVNGVSLSVKQGeivglL----GPNGAGKTTTFYMIVGLVKPDSGKILLDGQDI---TKLPMHKRA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  77 YNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPE 156
Cdd:cd03218   74 RLGIGYLPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPK 153

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 736694016 157 IIIADEPTKALDLLAANKIMTELKKIAKERIVIIVT 192
Cdd:cd03218  154 FLLLDEPFAGVDPIAVQDIQKIIKILKDRGIGVLIT 189
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
28-212 1.07e-26

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 108.42  E-value: 1.07e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  28 LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdYYYNSIGFIWQDYQLIEYLSVECNIDLVLSLSN 107
Cdd:PRK10908  30 MAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVP-FLRRQIGMIFQDHHLLMDRTVYDNVAIPLIIAG 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 108 LNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERI 187
Cdd:PRK10908 109 ASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDALSEGILRLFEEFNRVGV 188

                        170       180
                 ....*....|....*....|....*..
gi 736694016 188 -VIIVTHDKGLIEK-DANVYSMEQGQL 212
Cdd:PRK10908 189 tVLMATHDIGLISRrSYRMLTLSDGHL 215
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 16-203 1.53e-26

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 107.34  E-value: 1.53e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  16 VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNqsmKRFTKKELsdyyYNSIGFIWQD--YQLIEy 92
Cdd:cd03226   15 ILDDLSLDLYAGeIIALTGKNGAGKTTLAKILAGLIKESSGSILLNG---KPIKAKER----RKSIGYVMQDvdYQLFT- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  93 lsveCNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAA 172
Cdd:cd03226   87 ----DSVREELLLGLKELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKNM 162

                        170       180       190
                 ....*....|....*....|....*....|..
gi 736694016 173 NKIMTELKKIAKE-RIVIIVTHDKGLIEKDAN 203
Cdd:cd03226  163 ERVGELIRELAAQgKAVIVITHDYEFLAKVCD 194
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 2-216 1.62e-26

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 107.75  E-value: 1.62e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNqsmkrftkKELSDYYYNSI 80
Cdd:cd03269    1 LEVENVTKRFGRVTALDDISFSVEKGEIFgLLGPNGAGKTTTIRMILGIILPDSGEVLFDG--------KPLDIAARNRI 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIA 160
Cdd:cd03269   73 GYLPEERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLIL 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 161 DEPTKALDLLAANKIMTELKKIA-KERIVIIVTHDKGLIEKDAN-VYSMEQGQLKLVG 216
Cdd:cd03269  153 DEPFSGLDPVNVELLKDVIRELArAGKTVILSTHQMELVEELCDrVLLLNKGRAVLYG 210
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
1-194 2.23e-26

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 108.63  E-value: 2.23e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKElsdyyyns 79
Cdd:PRK11248   1 MLQISHLYADYGGKPALEDINLTLESGeLLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER-------- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 iGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:PRK11248  73 -GVVFQNEGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLL 151

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAKE--RIVIIVTHD 194
Cdd:PRK11248 152 LDEPFGALDAFTREQMQTLLLKLWQEtgKQVLLITHD 188
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 33-204 2.93e-26

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 106.80  E-value: 2.93e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISG-MDQNF--EGDVYFNNQSM------KRftkkelsdyyynSIGFIWQDYQLIEYLSVECNIDLVL 103
Cdd:COG4136   34 GPSGSGKSTLLAAIAGtLSPAFsaSGEVLLNGRRLtalpaeQR------------RIGILFQDDLLFPHLSVGENLAFAL 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 104 SlSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDL-LAANkiMTEL--K 180
Cdd:COG4136  102 P-PTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAaLRAQ--FREFvfE 178

                        170       180
                 ....*....|....*....|....*
gi 736694016 181 KIAKERI-VIIVTHDKGLIEKDANV 204
Cdd:COG4136  179 QIRQRGIpALLVTHDEEDAPAAGRV 203
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
2-194 3.44e-26

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 110.81  E-value: 3.44e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKGlNF--IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKElsdyyyNS 79
Cdd:PRK09452  15 VELRGISKSFDGKEVISNLDLTINNG-EFltLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAEN------RH 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:PRK09452  88 VNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLL 167

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAKERIV--IIVTHD 194
Cdd:PRK09452 168 LDESLSALDYKLRKQMQNELKALQRKLGItfVFVTHD 204
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
4-195 3.78e-26

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 110.70  E-value: 3.78e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   4 LIEIK---KVFGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKkelsdyYYNS 79
Cdd:PRK11607  19 LLEIRnltKSFDGQHAVDDVSLTIYKGEIFaLLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPP------YQRP 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:PRK11607  93 INMMFQSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLL 172

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAkERI---VIIVTHDK 195
Cdd:PRK11607 173 LDEPMGALDKKLRDRMQLEVVDIL-ERVgvtCVMVTHDQ 210
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 3-193 4.94e-26

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 107.48  E-value: 4.94e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   3 SLIEIKKV---FGNEIVLNHLSGDFQKGLN-FIYGPSGSGKTTLLNIISG------------MDQNFEG-DV-------- 57
Cdd:COG1119    2 PLLELRNVtvrRGGKTILDDISWTVKPGEHwAILGPNGAGKSTLLSLITGdlpptygndvrlFGERRGGeDVwelrkrig 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  58 YFNNQSMKRFTKKE------LSDYYyNSIGfIWQDYQlieylsvecnidlvlslsnlnkAERKMKVAKVLEELGISGLAK 131
Cdd:COG1119   82 LVSPALQLRFPRDEtvldvvLSGFF-DSIG-LYREPT----------------------DEQRERARELLELLGLAHLAD 137

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 736694016 132 MKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERI--VIIVTH 193
Cdd:COG1119  138 RPFGTLSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAptLVLVTH 201
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
2-220 8.13e-26

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 106.98  E-value: 8.13e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQ----------SMKRFTKK 70
Cdd:PRK10619   6 LNVIDLHKRYGEHEVLKGVSLQANAGdVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQtinlvrdkdgQLKVADKN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  71 ELSdYYYNSIGFIWQDYQLIEYLSVECNI-DLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKV-AKLSGGQKQRVAIA 148
Cdd:PRK10619  86 QLR-LLRTRLTMVFQHFNLWSHMTVLENVmEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYpVHLSGGQQQRVSIA 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 736694016 149 RALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTHDKGLIEKDAN-VYSMEQGQLKLVGQSKQ 220
Cdd:PRK10619 165 RALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEgKTMVVVTHEMGFARHVSShVIFLHQGKIEEEGAPEQ 238
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 2-220 9.53e-26

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 106.76  E-value: 9.53e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKV---FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEG-----DVYFN-NQSMKRftKKE 71
Cdd:PRK11264   1 MSAIEVKNLvkkFHGQTVLHGIDLEVKPGeVVAIIGPSGSGKTTLLRCINLLEQPEAGtirvgDITIDtARSLSQ--QKG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  72 LSDYYYNSIGFIWQDYQLIEYLSVECN-IDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARA 150
Cdd:PRK11264  79 LIRQLRQHVGFVFQNFNLFPHRTVLENiIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARA 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 736694016 151 LVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTHDKGLIEKDAN-VYSMEQGQLKLVGQSKQ 220
Cdd:PRK11264 159 LAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEkRTMVIVTHEMSFARDVADrAIFMDQGRIVEQGPAKA 230
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 1-192 1.54e-25

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 105.50  E-value: 1.54e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-----LnfiyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSM------KRFTK 69
Cdd:COG1137    3 TLEAENLVKSYGKRTVVKDVSLEVNQGeivglL----GPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDIthlpmhKRARL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  70 kelsdyyynSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIAR 149
Cdd:COG1137   79 ---------GIGYLPQEASIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIAR 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 736694016 150 ALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIVT 192
Cdd:COG1137  150 ALATNPKFILLDEPFAGVDPIAVADIQKIIRHLKERGIGVLIT 192
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 31-216 3.00e-25

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 104.17  E-value: 3.00e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRftkkelSDYYYNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNK 110
Cdd:TIGR01277  29 IMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTG------LAPYQRPVSMLFQENNLFAHLTVRQNIGLGLHPGLKLN 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  111 AERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IV 188
Cdd:TIGR01277 103 AEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQLCSERqrTL 182

                         170       180
                  ....*....|....*....|....*....
gi 736694016  189 IIVTHD-KGLIEKDANVYSMEQGQLKLVG 216
Cdd:TIGR01277 183 LMVTHHlSDARAIASQIAVVSQGKIKVVS 211
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
5-193 3.97e-25

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 110.25  E-value: 3.97e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   5 IEIKKV-F---GNEIVLNHLSGDFQKG--LNFIyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELsdyyYN 78
Cdd:COG1132  340 IEFENVsFsypGDRPVLKDISLTIPPGetVALV-GPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESL----RR 414

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  79 SIGFIWQDYQLIEyLSVECNIdlvlSLSNLN----KAERKMKVAKVLEElgISGLAK---MKV----AKLSGGQKQRVAI 147
Cdd:COG1132  415 QIGVVPQDTFLFS-GTIRENI----RYGRPDatdeEVEEAAKAAQAHEF--IEALPDgydTVVgergVNLSGGQRQRIAI 487

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 736694016 148 ARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIVTH 193
Cdd:COG1132  488 ARALLKDPPILILDEATSALDTETEALIQEALERLMKGRTTIVIAH 533
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
2-195 4.39e-25

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 107.11  E-value: 4.39e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkrfTKKELSDyyyNSI 80
Cdd:PRK11432   7 VVLKNITKRFGSNTVIDNLNLTIKQGtMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDV---THRSIQQ---RDI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIA 160
Cdd:PRK11432  81 CMVFQSYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLF 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 736694016 161 DEPTKALDllaAN--KIMTELKKIAKERIVII---VTHDK 195
Cdd:PRK11432 161 DEPLSNLD---ANlrRSMREKIRELQQQFNITslyVTHDQ 197
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
2-212 5.89e-25

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 103.94  E-value: 5.89e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNI-------------ISGMDQNFEGDVyfnNQSMKRF 67
Cdd:COG4161    3 IQLKNINCFYGSHQALFDINLECPSGETLvLLGPSGAGKSSLLRVlnlletpdsgqlnIAGHQFDFSQKP---SEKAIRL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  68 TKKElsdyyynsIGFIWQDYQLIEYLSVECN-IDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVA 146
Cdd:COG4161   80 LRQK--------VGMVFQQYNLWPHLTVMENlIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVA 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 147 IARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIV-IIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:COG4161  152 IARALMMEPQVLLFDEPTAALDPEITAQVVEIIRELSQTGITqVIVTHEVEFARKVASqVVYMEKGRI 219
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 2-212 1.07e-24

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 103.29  E-value: 1.07e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYynsI 80
Cdd:cd03219    1 LEVRGLTKRFGGLVALDDVSFSVRPGeIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIARLG---I 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQDYQLIEYLSVECNIDLV--------LSLSNLNKAERKM--KVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARA 150
Cdd:cd03219   78 GRTFQIPRLFPELTVLENVMVAaqartgsgLLLARARREEREAreRAEELLERVGLADLADRPAGELSYGQQRRLEIARA 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 736694016 151 LVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERI-VIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:cd03219  158 LATDPKLLLLDEPAAGLNPEETEELAELIRELRERGItVLLVEHDMDVVMSLADrVTVLDQGRV 221
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 31-212 1.37e-24

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 102.28  E-value: 1.37e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQLIeYLSVECNIDLVLSLSNLNK 110
Cdd:cd03245   35 IIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLR----RNIGYVPQDVTLF-YGTLRDNITLGAPLADDER 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 111 AERKMKVAKVLEELGIS--GLAKM---KVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE 185
Cdd:cd03245  110 ILRAAELAGVTDFVNKHpnGLDLQigeRGRGLSGGQRQAVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGD 189

                        170       180
                 ....*....|....*....|....*..
gi 736694016 186 RIVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:cd03245  190 KTLIIITHRPSLLDLVDRIIVMDSGRI 216
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 15-220 1.78e-24

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 103.69  E-value: 1.78e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   15 IVLNHLSGDFQKGLNF-------------------IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDY 75
Cdd:TIGR04521   1 IKLKNVSYIYQPGTPFekkalddvsltiedgefvaIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKKLKDL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   76 YYNsIGFIWQ--DYQLIEyLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGIS-GLAKMKVAKLSGGQKQRVAIARALV 152
Cdd:TIGR04521  81 RKK-VGLVFQfpEHQLFE-ETVYKDIAFGPKNLGLSEEEAEERVKEALELVGLDeEYLERSPFELSGGQMRRVAIAGVLA 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 736694016  153 KDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHDKGLIEKDAN-VYSMEQGQLKLVGQSKQ 220
Cdd:TIGR04521 159 MEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKglTVILVTHSMEDVAEYADrVIVMHKGKIVLDGTPRE 229
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 5-220 3.25e-24

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 102.51  E-value: 3.25e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    5 IEIKKVF-----GNEIVLNHLSGDFQKGlNF--IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNqsMKRFTKKELSDYYy 77
Cdd:TIGR04520   1 IEVENVSfsypeSEKPALKNVSLSIEKG-EFvaIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDG--LDTLDEENLWEIR- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   78 NSIGFIWQ--DYQLIEyLSVEcnIDLVLSLSNLNKAERKMK--VAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVK 153
Cdd:TIGR04520  77 KKVGMVFQnpDNQFVG-ATVE--DDVAFGLENLGVPREEMRkrVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAM 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 736694016  154 DPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHDkglIEKDAN---VYSMEQGQLKLVGQSKQ 220
Cdd:TIGR04520 154 RPDIIILDEATSMLDPKGRKEVLETIRKLNKEEgiTVISITHD---MEEAVLadrVIVMNKGKIVAEGTPRE 222
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
4-200 5.25e-24

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 101.32  E-value: 5.25e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   4 LIEIKKV---FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMK------RFTKKEls 73
Cdd:PRK09493   1 MIEFKNVskhFGPTQVLHNIDLNIDQGeVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNdpkvdeRLIRQE-- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  74 dyyynsIGFIWQDYQLIEYLSVECNIDL-VLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALV 152
Cdd:PRK09493  79 ------AGMVFQQFYLFPHLTALENVMFgPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALA 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 736694016 153 KDPEIIIADEPTKALDLLAANKIMTELKKIAKERI-VIIVTHDKGLIEK 200
Cdd:PRK09493 153 VKPKLMLFDEPTSALDPELRHEVLKVMQDLAEEGMtMVIVTHEIGFAEK 201
3a0107s01c2 TIGR00972
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ...
 4-193 7.54e-24

phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]


Pssm-ID: 273372 [Multi-domain]  Cd Length: 247  Bit Score: 100.83  E-value: 7.54e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    4 LIEIKKV---FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMD-----QNFEGDVYFNNQSM--KRFTKKEL 72
Cdd:TIGR00972   1 AIEIENLnlfYGEKEALKNINLDIPKNqVTALIGPSGCGKSTLLRSLNRMNdlvpgVRIEGKVLFDGQDIydKKIDVVEL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   73 SdyyyNSIGFIWQDYQLIEyLSVECNIDLVLSLSNL-NKAERKMKVAKVLEELGISGLAKMKVAK----LSGGQKQRVAI 147
Cdd:TIGR00972  81 R----RRVGMVFQKPNPFP-MSIYDNIAYGPRLHGIkDKKELDEIVEESLKKAALWDEVKDRLHDsalgLSGGQQQRLCI 155

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 736694016  148 ARALVKDPEIIIADEPTKALDLLAANKI---MTELKkiaKERIVIIVTH 193
Cdd:TIGR00972 156 ARALAVEPEVLLLDEPTSALDPIATGKIeelIQELK---KKYTIVIVTH 201
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 33-220 1.08e-23

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 99.82  E-value: 1.08e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYyynSIGFIWQDYQLIEYLSVECNidLVLSLSNLNKAE 112
Cdd:cd03224   33 GRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARA---GIGYVPEGRRIFPELTVEEN--LLLGAYARRRAK 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 113 RKMKVAKVLEELGIsgLAKM---KVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVI 189
Cdd:cd03224  108 RKARLERVYELFPR--LKERrkqLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDEGVTI 185

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 736694016 190 IvthdkgLIEKDAN--------VYSMEQGQLKLVGQSKQ 220
Cdd:cd03224  186 L------LVEQNARfaleiadrAYVLERGRVVLEGTAAE 218
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 6-190 1.64e-23

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 98.83  E-value: 1.64e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   6 EIKKVFGNEIVLNHLSGDFQKGLnfIY---GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKelsdyyYNSIGF 82
Cdd:cd03268    5 DLTKTYGKKRVLDDISLHVKKGE--IYgflGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEA------LRRIGA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  83 IWQDYQLIEYLSVECNidlvLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADE 162
Cdd:cd03268   77 LIEAPGFYPNLTAREN----LRLLARLLGIRKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDE 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 736694016 163 PTKALD--------------------LLAANKIMTELKKIAkERIVII 190
Cdd:cd03268  153 PTNGLDpdgikelrelilslrdqgitVLISSHLLSEIQKVA-DRIGII 199
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 33-210 1.84e-23

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 99.70  E-value: 1.84e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSM---KRFTKKELSDYYYNsIGFIWQDYQLIEYLSVECN-IDLVLSLSNL 108
Cdd:PRK11124  35 GPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFdfsKTPSDKAIRELRRN-VGMVFQQYNLWPHLTVQQNlIEAPCRVLGL 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 109 NKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIV 188
Cdd:PRK11124 114 SKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETGIT 193

                        170       180
                 ....*....|....*....|....*
gi 736694016 189 -IIVTHDKGLIEKDAN--VYsMEQG 210
Cdd:PRK11124 194 qVIVTHEVEVARKTASrvVY-MENG 217
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
1-216 2.52e-23

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 101.87  E-value: 2.52e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSlIEIKKVFGNeivlNHLSGDFQ---KGLNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYY 77
Cdd:PRK11144   1 MLE-LNFKQQLGD----LCLTVNLTlpaQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKGICLPPEK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  78 NSIGFIWQDYQLIEYLSVEcnidlvlslSNLN---KAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKD 154
Cdd:PRK11144  76 RRIGYVFQDARLFPHYKVR---------GNLRygmAKSMVAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTA 146

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 736694016 155 PEIIIADEPTKALDLLAANKIMTELKKIAKE-RIVII-VTHDKGLIEKDA-NVYSMEQGQLKLVG 216
Cdd:PRK11144 147 PELLLMDEPLASLDLPRKRELLPYLERLAREiNIPILyVSHSLDEILRLAdRVVVLEQGKVKAFG 211
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 1-200 2.80e-23

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 100.57  E-value: 2.80e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKGLnfIY---GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTkkelsdyyY 77
Cdd:COG4152    1 MLELKGLTKRFGDKTAVDDVSFTVPKGE--IFgllGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPED--------R 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  78 NSIGF------IWQDYQLIE---YLSvecnidlvlSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIA 148
Cdd:COG4152   71 RRIGYlpeergLYPKMKVGEqlvYLA---------RLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLI 141

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 736694016 149 RALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTHDKGLIEK 200
Cdd:COG4152  142 AALLHDPELLILDEPFSGLDPVNVELLKDVIRELAAKgTTVIFSSHQMELVEE 194
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1-194 2.86e-23

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 101.84  E-value: 2.86e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEI-VLNHLSGDFQKGlNFI--YGPSGSGKTTLLNIISGMDQNFEGDVYFNNqsmKRFTKKELSDyyy 77
Cdd:PRK11650   3 GLKLQAVRKSYDGKTqVIKGIDLDVADG-EFIvlVGPSGCGKSTLLRMVAGLERITSGEIWIGG---RVVNELEPAD--- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  78 NSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEI 157
Cdd:PRK11650  76 RDIAMVFQNYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAV 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 736694016 158 IIADEPTKALD--LLAANKImtELKKIAKERIV--IIVTHD 194
Cdd:PRK11650 156 FLFDEPLSNLDakLRVQMRL--EIQRLHRRLKTtsLYVTHD 194
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
11-198 3.65e-23

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 97.30  E-value: 3.65e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  11 FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVyfnnqsmKRFTKKelsdyyynSIGFIWQDYQL 89
Cdd:NF040873   2 YGGRPVLHGVDLTIPAGsLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV-------RRAGGA--------RVAYVPQRSEV 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  90 IEYL--SVEcniDLV--------LSLSNLNKAERkMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:NF040873  67 PDSLplTVR---DLVamgrwarrGLWRRLTRDDR-AAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLL 142

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTHDKGLI 198
Cdd:NF040873 143 LDEPTTGLDAESRERIIALLAEEHARgATVVVVTHDLELV 182
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 1-193 4.89e-23

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 97.82  E-value: 4.89e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNE----IVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGM---DQNF---EG-DVYFNNQSMKRft 68
Cdd:cd03266    1 MITADALTKRFRDVkktvQAVDGVSFTVKPGEVTgLLGPNGAGKTTTLRMLAGLlepDAGFatvDGfDVVKEPAEARR-- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  69 kkelsdyyynSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIA 148
Cdd:cd03266   79 ----------RLGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIA 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 736694016 149 RALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTH 193
Cdd:cd03266  149 RALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRALgKCILFSTH 194
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 7-194 5.30e-23

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 103.25  E-value: 5.30e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   7 IKKVFGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTT----LLNIISGmdqnfEGDVYFNNQSMKRFTKKELSDYYYNsIG 81
Cdd:PRK15134 292 LKRTVDHNVVVKNISFTLRPGETLgLVGESGSGKSTtglaLLRLINS-----QGEIWFDGQPLHNLNRRQLLPVRHR-IQ 365

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  82 FIWQD--YQLIEYLSVECNID--LVLSLSNLNKAERKMKVAKVLEELGISGLAKMKV-AKLSGGQKQRVAIARALVKDPE 156
Cdd:PRK15134 366 VVFQDpnSSLNPRLNVLQIIEegLRVHQPTLSAAQREQQVIAVMEEVGLDPETRHRYpAEFSGGQRQRIAIARALILKPS 445

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 736694016 157 IIIADEPTKALDLLAANKIMTELKKI-AKERIV-IIVTHD 194
Cdd:PRK15134 446 LIILDEPTSSLDKTVQAQILALLKSLqQKHQLAyLFISHD 485
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
1-193 5.48e-23

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 102.79  E-value: 5.48e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-----LnfiyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDy 75
Cdd:COG1129    4 LLEMRGISKSFGGVKALDGVSLELRPGevhalL----GENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRDAQA- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  76 yyNSIGFIWQDYQLIEYLSVECNI---DLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALV 152
Cdd:COG1129   79 --AGIAIIHQELNLVPNLSVAENIflgREPRRGGLIDWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALS 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 736694016 153 KDPEIIIADEPTKALD------LLaanKIMTELKK--IAkeriVIIVTH 193
Cdd:COG1129  157 RDARVLILDEPTASLTereverLF---RIIRRLKAqgVA----IIYISH 198
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 16-231 9.11e-23

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 97.30  E-value: 9.11e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  16 VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQLIeYLS 94
Cdd:cd03251   17 VLRDISLDIPAGeTVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASLR----RQIGLVSQDVFLF-NDT 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  95 VECNIDLVLSLSNLNKAERKMKVAKVLE-----------ELGISGLakmkvaKLSGGQKQRVAIARALVKDPEIIIADEP 163
Cdd:cd03251   92 VAENIAYGRPGATREEVEEAARAANAHEfimelpegydtVIGERGV------KLSGGQRQRIAIARALLKDPPILILDEA 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 164 TKALDLLAANKIMTELKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVGQSKQHSKDDGKNNRL 231
Cdd:cd03251  166 TSALDTESERLVQAALERLMKNRTTFVIAHRLSTIENADRIVVLEDGKIVERGTHEELLAQGGVYAKL 233
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 31-199 1.17e-22

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 101.98  E-value: 1.17e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTkkelSDYYYNSIGFIWQDYQLIEYlSVECNIDLVL---SLSN 107
Cdd:TIGR02857 353 LVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADAD----ADSWRDQIAWVPQHPFLFAG-TIAENIRLARpdaSDAE 427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  108 LNKAERKMKVAKVLEELGiSGLAKM---KVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAK 184
Cdd:TIGR02857 428 IREALERAGLDEFVAALP-QGLDTPigeGGAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQ 506

                         170
                  ....*....|....*
gi 736694016  185 ERIVIIVTHDKGLIE 199
Cdd:TIGR02857 507 GRTVLLVTHRLALAA 521
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
11-194 1.42e-22

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 97.39  E-value: 1.42e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  11 FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQL 89
Cdd:PRK11231  12 YGTKRILNDLSLSLPTGkITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLA----RRLALLPQHHLT 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  90 IEYLSVEcniDLV-------LSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADE 162
Cdd:PRK11231  88 PEGITVR---ELVaygrspwLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDE 164

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 736694016 163 PTKALDL---LAANKIMTELKkiAKERIVIIVTHD 194
Cdd:PRK11231 165 PTTYLDInhqVELMRLMRELN--TQGKTVVTVLHD 197
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 7-214 3.26e-22

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 100.52  E-value: 3.26e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   7 IKKVFGNEIVLNHLSGDFQKG--LNFIyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQsmkrftkkelsdyyyNSIGFIW 84
Cdd:COG0488    4 LSKSFGGRPLLDDVSLSINPGdrIGLV-GRNGAGKSTLLKILAGELEPDSGEVSIPKG---------------LRIGYLP 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  85 QDYQLIEYLSVecnIDLVLS--------LSNLNKAERKM---------------------------KVAKVLEELGISG- 128
Cdd:COG0488   68 QEPPLDDDLTV---LDTVLDgdaelralEAELEELEAKLaepdedlerlaelqeefealggweaeaRAEEILSGLGFPEe 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 129 LAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKerIVIIVTHDKGLIEKDAN-VYSM 207
Cdd:COG0488  145 DLDRPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKNYPG--TVLVVSHDRYFLDRVATrILEL 222


                 ....*..
gi 736694016 208 EQGQLKL 214
Cdd:COG0488  223 DRGKLTL 229
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 26-193 3.96e-22

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 95.76  E-value: 3.96e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  26 KGLNF---------IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKkelsDYYYNSIGFIWQDYQL----IEY 92
Cdd:cd03253   18 KDVSFtipagkkvaIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTL----DSLRRAIGVVPQDTVLfndtIGY 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  93 lsvecNIdlvlSLSNLNKAERKM----KVAKVLEE-----------LGISGLakmkvaKLSGGQKQRVAIARALVKDPEI 157
Cdd:cd03253   94 -----NI----RYGRPDATDEEVieaaKAAQIHDKimrfpdgydtiVGERGL------KLSGGEKQRVAIARAILKNPPI 158

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 736694016 158 IIADEPTKALDLLAANKIMTELKKIAKERIVIIVTH 193
Cdd:cd03253  159 LLLDEATSALDTHTEREIQAALRDVSKGRTTIVIAH 194
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 15-211 4.40e-22

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 95.68  E-value: 4.40e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  15 IVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIIsgmdQNF----EGDVYFNNQSMKRFTKKELSDyyynSIGFIWQDYQL 89
Cdd:cd03249   17 PILKGLSLTIPPGKTVaLVGSSGCGKSTVVSLL----ERFydptSGEILLDGVDIRDLNLRWLRS----QIGLVSQEPVL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  90 IeYLSVECNIDLVLSLSNLNKAERKMKVA---KVLEEL--GISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPT 164
Cdd:cd03249   89 F-DGTIAENIRYGKPDATDEEVEEAAKKAnihDFIMSLpdGYDTLVGERGSQLSGGQKQRIAIARALLRNPKILLLDEAT 167

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 736694016 165 KALDLLAANKIMTELKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQ 211
Cdd:cd03249  168 SALDAESEKLVQEALDRAMKGRTTIVIAHRLSTIRNADLIAVLQNGQ 214
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 5-194 7.41e-22

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 95.15  E-value: 7.41e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   5 IEIKKV---FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIIS---GMDQnfeGDVYFNNQSMKRFTKKELSdyyy 77
Cdd:COG4604    2 IEIKNVskrYGGKVVLDDVSLTIPKGgITALIGPNGAGKSTLLSMISrllPPDS---GEVLVDGLDVATTPSRELA---- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  78 NSIGFIWQDYQLIEYLSVEcniDLVL------SLSNLNKAERKmKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARAL 151
Cdd:COG4604   75 KRLAILRQENHINSRLTVR---ELVAfgrfpySKGRLTAEDRE-IIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVL 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 736694016 152 VKDPEIIIADEPTKALDLLAANKIMTELKKIAKE--RIVIIVTHD 194
Cdd:COG4604  151 AQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADElgKTVVIVLHD 195
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 6-193 8.39e-22

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 94.98  E-value: 8.39e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   6 EIKKVFGNEIVLNHLSGDF-QKGLNFIYGPSGSGKTTLLNIISGM-----DQNFEGDVYFNNQSMKRFTKKELSdyyyNS 79
Cdd:PRK14247   8 DLKVSFGQVEVLDGVNLEIpDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDIFKMDVIELR----RR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNIDLVLSLSNL--NKAERKMKVAKVLEELGISGLAKMKV----AKLSGGQKQRVAIARALVK 153
Cdd:PRK14247  84 VQMVFQIPNPIPNLSIFENVALGLKLNRLvkSKKELQERVRWALEKAQLWDEVKDRLdapaGKLSGGQQQRLCIARALAF 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 736694016 154 DPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIVTH 193
Cdd:PRK14247 164 QPEVLLADEPTANLDPENTAKIESLFLELKKDMTIVLVTH 203
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
31-193 8.55e-22

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 94.65  E-value: 8.55e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFT--KKELSdyyynsigFIWQDYQLIEYLSVECNIDLVLSLS-N 107
Cdd:PRK10771  30 ILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPpsRRPVS--------MLFQENNLFSHLTVAQNIGLGLNPGlK 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 108 LNKAERKmKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER- 186
Cdd:PRK10771 102 LNAAQRE-KLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQVCQERq 180


                 ....*...
gi 736694016 187 -IVIIVTH 193
Cdd:PRK10771 181 lTLLMVSH 188
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 33-212 1.89e-21

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 98.22  E-value: 1.89e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKT-TLLNIISGMDQNF---EGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQD------------YQLIEylsve 96
Cdd:COG4172   43 GESGSGKSvTALSILRLLPDPAahpSGSILFDGQDLLGLSERELRRIRGNRIAMIFQEpmtslnplhtigKQIAE----- 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  97 cnidlVLSL-SNLNKAERKMKVAKVLEELGISGlAKMKVAK----LSGGQKQRVAIARALVKDPEIIIADEPTKALDLLA 171
Cdd:COG4172  118 -----VLRLhRGLSGAAARARALELLERVGIPD-PERRLDAyphqLSGGQRQRVMIAMALANEPDLLIADEPTTALDVTV 191

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 736694016 172 ANKIMTELKKIAKER---IVIIvTHDKGLIEKDA-NVYSMEQGQL 212
Cdd:COG4172  192 QAQILDLLKDLQRELgmaLLLI-THDLGVVRRFAdRVAVMRQGEI 235
COG4674 COG4674
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 1-212 2.37e-21

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443710 [Multi-domain]  Cd Length: 250  Bit Score: 93.64  E-value: 2.37e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRftkkeLSDYYYNS 79
Cdd:COG4674   10 ILYVEDLTVSFDGFKALNDLSLYVDPGeLRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDLTG-----LDEHEIAR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGfIWQDYQ---LIEYLSVECNIDLVLS-----LSNL---NKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIA 148
Cdd:COG4674   85 LG-IGRKFQkptVFEELTVFENLELALKgdrgvFASLfarLTAEERDRIEEVLETIGLTDKADRLAGLLSHGQKQWLEIG 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 736694016 149 RALVKDPEIIIADEPTkaldllAAnkiMTE---------LKKIAKERIVIIVTHDKGLIEK-DANVYSMEQGQL 212
Cdd:COG4674  164 MLLAQDPKLLLLDEPV------AG---MTDaetertaelLKSLAGKHSVVVVEHDMEFVRQiARKVTVLHQGSV 228
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 12-212 2.42e-21

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 91.51  E-value: 2.42e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  12 GNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYyynsIGFIWQDYQLI 90
Cdd:cd03246   13 AEPPVLRNVSFSIEPGESLaIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDH----VGYLPQDDELF 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  91 EYlSVECNIdlvlslsnlnkaerkmkvakvleelgisglakmkvakLSGGQKQRVAIARALVKDPEIIIADEPTKALDLL 170
Cdd:cd03246   89 SG-SIAENI-------------------------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVE 130

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 736694016 171 AANKIMTELKKI-AKERIVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:cd03246  131 GERALNQAIAALkAAGATRIVIAHRPETLASADRILVLEDGRV 173
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
1-196 4.88e-21

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 92.94  E-value: 4.88e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQS--MKRFTKKELS---- 73
Cdd:COG4598    8 ALEVRDLHKSFGDLEVLKGVSLTARKGdVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEirLKPDRDGELVpadr 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  74 ---DYYYNSIGFIWQDYQLIEYLSVECNIDL----VLSLSnlnKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVA 146
Cdd:COG4598   88 rqlQRIRTRLGMVFQSFNLWSHMTVLENVIEapvhVLGRP---KAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAA 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 736694016 147 IARALVKDPEIIIADEPTKALD------LLaanKIMTELkkiAKE-RIVIIVTHDKG 196
Cdd:COG4598  165 IARALAMEPEVMLFDEPTSALDpelvgeVL---KVMRDL---AEEgRTMLVVTHEMG 215
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 12-212 9.22e-21

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 92.14  E-value: 9.22e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  12 GNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDY-----YYNSIGFIWq 85
Cdd:PRK13548  13 GGRTLLDDVSLTLRPGeVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARRravlpQHSSLSFPF- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  86 dyqlieylSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALV------KDPEIII 159
Cdd:PRK13548  92 --------TVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdGPPRWLL 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHDKGLiekdANVYS-----MEQGQL 212
Cdd:PRK13548 164 LDEPTSALDLAHQHHVLRLARQLAHERglAVIVVLHDLNL----AARYAdrivlLHQGRL 219
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 5-193 9.64e-21

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 91.52  E-value: 9.64e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   5 IEIKKV-FG---NEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNS 79
Cdd:cd03254    3 IEFENVnFSydeKKPVLKDINFSIKPGETVaIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLR----SM 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYlSVECNIDLVlslSNLNKAERKMKVAKVL--------------EELGISGlakmkvAKLSGGQKQRV 145
Cdd:cd03254   79 IGVVLQDTFLFSG-TIMENIRLG---RPNATDEEVIEAAKEAgahdfimklpngydTVLGENG------GNLSQGERQLL 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 736694016 146 AIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIVTH 193
Cdd:cd03254  149 AIARAMLRDPKILILDEATSNIDTETEKLIQEALEKLMKGRTSIIIAH 196
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 16-219 1.08e-20

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 92.36  E-value: 1.08e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  16 VLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQ--DYQLIEy 92
Cdd:PRK13632  24 ALKNVSFEINEGEYVaILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKEIR----KKIGIIFQnpDNQFIG- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  93 LSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAA 172
Cdd:PRK13632  99 ATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKGK 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 736694016 173 N---KIMTELKKIAKeRIVIIVTHDKGLIEKDANVYSMEQGQLKLVGQSK 219
Cdd:PRK13632 179 ReikKIMVDLRKTRK-KTLISITHDMDEAILADKVIVFSEGKLIAQGKPK 227
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 26-220 1.14e-20

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 92.45  E-value: 1.14e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  26 KGLNF---------IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKrFTKKELSDYYyNSIGFIWQ--DYQLIEyLS 94
Cdd:PRK13639  19 KGINFkaekgemvaLLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIK-YDKKSLLEVR-KTVGIVFQnpDDQLFA-PT 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  95 VECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANK 174
Cdd:PRK13639  96 VEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQ 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 736694016 175 IMTELKKIAKERIVIIV-THDKGLIEKDAN-VYSMEQGQLKLVGQSKQ 220
Cdd:PRK13639 176 IMKLLYDLNKEGITIIIsTHDVDLVPVYADkVYVMSDGKIIKEGTPKE 223
galliderm_ABC TIGR03740
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ...
 7-192 1.38e-20

gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.


Pssm-ID: 163452 [Multi-domain]  Cd Length: 223  Bit Score: 90.92  E-value: 1.38e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    7 IKKVFGNEIVLNHLSGDFQKglNFIY---GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkrfTKKELSDyyynsIGFI 83
Cdd:TIGR03740   6 LSKRFGKQTAVNNISLTVPK--NSVYgllGPNGAGKSTLLKMITGILRPTSGEIIFDGHPW---TRKDLHK-----IGSL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   84 WQDYQLIEYLSVECNIDLVLSLSNLNKAErkmkVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEP 163
Cdd:TIGR03740  76 IESPPLYENLTARENLKVHTTLLGLPDSR----IDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKLLILDEP 151

                         170       180
                  ....*....|....*....|....*....
gi 736694016  164 TKALDLLAANKIMTELKKIAKERIVIIVT 192
Cdd:TIGR03740 152 TNGLDPIGIQELRELIRSFPEQGITVILS 180
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 31-212 1.44e-20

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 96.47  E-value: 1.44e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDyyynSIGFIWQDYQLIeYLSVECNIdlVLSLSNLNK 110
Cdd:TIGR03375 496 IIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPADLRR----NIGYVPQDPRLF-YGTLRDNI--ALGAPYADD 568

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  111 AErkmkVAKVLEELGISGLAK-------MKVAK----LSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTEL 179
Cdd:TIGR03375 569 EE----ILRAAELAGVTEFVRrhpdgldMQIGErgrsLSGGQRQAVALARALLRDPPILLLDEPTSAMDNRSEERFKDRL 644

                         170       180       190
                  ....*....|....*....|....*....|...
gi 736694016  180 KKIAKERIVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:TIGR03375 645 KRWLAGKTLVLVTHRTSLLDLVDRIIVMDNGRI 677
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
1-192 1.73e-20

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 91.61  E-value: 1.73e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKV---FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGM---DQNFEGDVYFNNQSMKRftKKELS 73
Cdd:PRK09984   1 MQTIIRVEKLaktFNQHQALHAVDLNIHHGeMVALLGPSGSGKSTLLRHLSGLitgDKSAGSHIELLGRTVQR--EGRLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  74 DYYYNS---IGFIWQDYQLIEYLSVECNIdLVLSLSNLN---------KAERKMKVAKVLEELGISGLAKMKVAKLSGGQ 141
Cdd:PRK09984  79 RDIRKSranTGYIFQQFNLVNRLSVLENV-LIGALGSTPfwrtcfswfTREQKQRALQALTRVGMVHFAHQRVSTLSGGQ 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 736694016 142 KQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAK-ERIVIIVT 192
Cdd:PRK09984 158 QQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQnDGITVVVT 209
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 17-194 2.26e-20

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 91.35  E-value: 2.26e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  17 LNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYyynsIGFIWQDYQlIEYLSV 95
Cdd:PRK13648  25 LKDVSFNIPKGqWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKH----IGIVFQNPD-NQFVGS 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  96 ECNIDLVLSLSNLNKAERKM--KVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAAN 173
Cdd:PRK13648 100 IVKYDVAFGLENHAVPYDEMhrRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQ 179

                        170       180
                 ....*....|....*....|...
gi 736694016 174 KIMTELKKIAKERIVII--VTHD 194
Cdd:PRK13648 180 NLLDLVRKVKSEHNITIisITHD 202
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
31-211 2.28e-20

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 91.44  E-value: 2.28e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQsmkrftKKELSDYYYNS--IGFIWQD--YQLIEYLSVECNIDLVLSL- 105
Cdd:COG4167   44 IIGENGSGKSTLAKMLAGIIEPTSGEILINGH------KLEYGDYKYRCkhIRMIFQDpnTSLNPRLNIGQILEEPLRLn 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 106 SNLNKAERKMKVAKVLEELGISG-LAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKI---MTELKK 181
Cdd:COG4167  118 TDLTAEEREERIFATLRLVGLLPeHANFYPHMLSSGQKQRVALARALILQPKIIIADEALAALDMSVRSQIinlMLELQE 197

                        170       180       190
                 ....*....|....*....|....*....|....
gi 736694016 182 ---IAkeriVIIVTHDKGLIEKDA-NVYSMEQGQ 211
Cdd:COG4167  198 klgIS----YIYVSQHLGIVKHISdKVLVMHQGE 227
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 31-220 3.42e-20

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 90.24  E-value: 3.42e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKkelsDYYYNSIGFIWQDYQLIEYlSVECNIDLVLSLSNLNK 110
Cdd:cd03252   33 IVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADP----AWLRRQVGVVLQENVLFNR-SIRDNIALADPGMSMER 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 111 AERKMKVAKVLE-----ELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE 185
Cdd:cd03252  108 VIEAAKLAGAHDfiselPEGYDTIVGEQGAGLSGGQRQRIAIARALIHNPRILIFDEATSALDYESEHAIMRNMHDICAG 187

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 736694016 186 RIVIIVTHDKGLIEKDANVYSMEQGqlKLVGQSKQ 220
Cdd:cd03252  188 RTVIIIAHRLSTVKNADRIIVMEKG--RIVEQGSH 220
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 13-216 4.20e-20

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 88.14  E-value: 4.20e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  13 NEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFtKKELSDYyynsIGFIWQDYQLIE 91
Cdd:cd03247   14 EQQVLKNLSLELKQGEKIaLLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDL-EKALSSL----ISVLNQRPYLFD 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  92 ylsvecnidlvlslsnlnkaerkmkvAKVLEELGIsglakmkvaKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLA 171
Cdd:cd03247   89 --------------------------TTLRNNLGR---------RFSGGERQRLALARILLQDAPIVLLDEPTVGLDPIT 133

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 736694016 172 ANKIMTELKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVG 216
Cdd:cd03247  134 ERQLLSLIFEVLKDKTLIWITHHLTGIEHMDKILFLENGKIIMQG 178
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
33-212 5.63e-20

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 90.13  E-value: 5.63e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYyNSIGFIWQDYqlIEYLSVECNIDLVLS-----LSN 107
Cdd:PRK10419  45 GRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRAQRKAFR-RDIQMVFQDS--ISAVNPRKTVREIIReplrhLLS 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 108 LNKAERKMKVAKVLEELGIS-GLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER 186
Cdd:PRK10419 122 LDKAERLARASEMLRAVDLDdSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQF 201

                        170       180
                 ....*....|....*....|....*....
gi 736694016 187 --IVIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:PRK10419 202 gtACLFITHDLRLVERFCQrVMVMDNGQI 230
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 2-194 9.56e-20

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 89.35  E-value: 9.56e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHL-----SGDFQKglnfIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKrftkkELSDyy 76
Cdd:PRK11247  13 LLLNAVSKRYGERTVLNQLdlhipAGQFVA----VVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLA-----EARE-- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  77 ynSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERkmkvakVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPE 156
Cdd:PRK11247  82 --DTRLMFQDARLLPWKKVIDNVGLGLKGQWRDAALQ------ALAAVGLADRANEWPAALSGGQKQRVALARALIHRPG 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 736694016 157 IIIADEPTKALDllAANKI-MTELkkIakERI-------VIIVTHD 194
Cdd:PRK11247 154 LLLLDEPLGALD--ALTRIeMQDL--I--ESLwqqhgftVLLVTHD 193
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 33-212 1.32e-19

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 88.30  E-value: 1.32e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKelsdYYYNSIGFIWQDYQLIEYlSVECNIDLVL---SLSNLN 109
Cdd:cd03248   47 GPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHK----YLHSKVSLVGQEPVLFAR-SLQDNIAYGLqscSFECVK 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 110 KAERKMKVAKVLEEL--GISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERI 187
Cdd:cd03248  122 EAAQKAHAHSFISELasGYDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSALDAESEQQVQQALYDWPERRT 201

                        170       180
                 ....*....|....*....|....*
gi 736694016 188 VIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:cd03248  202 VLVIAHRLSTVERADQILVLDGGRI 226
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 5-193 1.80e-19

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 88.56  E-value: 1.80e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   5 IEIKKV---FGNEIVLNHLSGDFQKG--LNFIyGPSGSGKTTLLNIISGM-----DQNFEGDVYFNNQSMkrftkkelsd 74
Cdd:COG1117   12 IEVRNLnvyYGDKQALKDINLDIPENkvTALI-GPSGCGKSTLLRCLNRMndlipGARVEGEILLDGEDI---------- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  75 yyYNSigfiwqDYQLIEY---------------LSVECNIDLVLSLS-NLNKAERKMKVAKVLEELGI----------SG 128
Cdd:COG1117   81 --YDP------DVDVVELrrrvgmvfqkpnpfpKSIYDNVAYGLRLHgIKSKSELDEIVEESLRKAALwdevkdrlkkSA 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 129 LAkmkvakLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKI---MTELKkiaKERIVIIVTH 193
Cdd:COG1117  153 LG------LSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIeelILELK---KDYTIVIVTH 211
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 1-212 1.94e-19

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 88.17  E-value: 1.94e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRftkkeLSDYYYNS 79
Cdd:COG0411    4 LLEVRGLTKRFGGLVAVDDVSLEVERGeIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITG-----LPPHRIAR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IG----FiwQDYQLIEYLSVECNI-------------DLVLSLSNLNKAERKM--KVAKVLEELGISGLAKMKVAKLSGG 140
Cdd:COG0411   79 LGiartF--QNPRLFPELTVLENVlvaaharlgrgllAALLRLPRARREEREAreRAEELLERVGLADRADEPAGNLSYG 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 736694016 141 QKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERI--VIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:COG0411  157 QQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGitILLIEHDMDLVMGLADrIVVLDFGRV 231
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 12-216 2.80e-19

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 91.64  E-value: 2.80e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   12 GNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKkelsDYYYNSIGFIWQDYQLI 90
Cdd:TIGR01842 329 GKKPTLRGISFSLQAGEALaIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDR----ETFGKHIGYLPQDVELF 404

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   91 EYlSVECNIDLVLSLSNLNKAERKMKVAKVLE-----------ELGISGlakmkvAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:TIGR01842 405 PG-TVAENIARFGENADPEKIIEAAKLAGVHElilrlpdgydtVIGPGG------ATLSGGQRQRIALARALYGDPKLVV 477

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 736694016  160 ADEPTKALD------LLAAnkiMTELKKiaKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVG 216
Cdd:TIGR01842 478 LDEPNSNLDeegeqaLANA---IKALKA--RGITVVVITHRPSLLGCVDKILVLQDGRIARFG 535
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 15-193 3.40e-19

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 91.65  E-value: 3.40e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   15 IVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQN---FEGDVYFNNQSMKRFTKKELSdyyynsiGFIWQDYQLI 90
Cdd:TIGR00955  39 HLLKNVSGVAKPGeLLAVMGSSGAGKTTLMNALAFRSPKgvkGSGSVLLNGMPIDAKEMRAIS-------AYVQQDDLFI 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   91 EYLSVEcnIDLVLSL-----SNLNKAERKMKVAKVLEELGISGLAKMK------VAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:TIGR00955 112 PTLTVR--EHLMFQAhlrmpRRVTKKEKRERVDEVLQALGLRKCANTRigvpgrVKGLSGGERKRLAFASELLTDPPLLF 189

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 736694016  160 ADEPTKALDLLAANKIMTELKKIA-KERIVIIVTH 193
Cdd:TIGR00955 190 CDEPTSGLDSFMAYSVVQVLKGLAqKGKTIICTIH 224
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 33-200 4.73e-19

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 86.62  E-value: 4.73e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNqsmkrFTKKELSDYYYNSIGFIW-QDYQLIEYLSVECNIDLVLSLSNLNKA 111
Cdd:cd03267   54 GPNGAGKTTTLKILSGLLQPTSGEVRVAG-----LVPWKRRKKFLRRIGVVFgQKTQLWWDLPVIDSFYLLAAIYDLPPA 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 112 ERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVI 189
Cdd:cd03267  129 RFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERgtTVL 208

                        170
                 ....*....|.
gi 736694016 190 IVTHDKGLIEK 200
Cdd:cd03267  209 LTSHYMKDIEA 219
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 26-216 6.82e-19

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 90.58  E-value: 6.82e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  26 KGLNF---------IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYyynsIGFIWQDYQLIEYlSVE 96
Cdd:COG4618  349 RGVSFslepgevlgVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELGRH----IGYLPQDVELFDG-TIA 423

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  97 CNIdlvlslSNLNKAERkmkvAKVLE--------------------ELGISGLAkmkvakLSGGQKQRVAIARALVKDPE 156
Cdd:COG4618  424 ENI------ARFGDADP----EKVVAaaklagvhemilrlpdgydtRIGEGGAR------LSGGQRQRIGLARALYGDPR 487

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 157 IIIADEPTKALD------LLAAnkiMTELKkiAKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVG 216
Cdd:COG4618  488 LVVLDEPNSNLDdegeaaLAAA---IRALK--ARGATVVVITHRPSLLAAVDKLLVLRDGRVQAFG 548
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 6-194 7.87e-19

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 85.50  E-value: 7.87e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   6 EIKKVFGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKelsdyYYNSIGFIW 84
Cdd:cd03265    5 NLVKKYGDFEAVRGVSFRVRRGEIFgLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPRE-----VRRRIGIVF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  85 QDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPT 164
Cdd:cd03265   80 QDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPT 159

                        170       180       190
                 ....*....|....*....|....*....|..
gi 736694016 165 KALDLLAANKIMTELKKIAKER--IVIIVTHD 194
Cdd:cd03265  160 IGLDPQTRAHVWEYIEKLKEEFgmTILLTTHY 191
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 12-194 8.69e-19

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 90.11  E-value: 8.69e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   12 GNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQLI 90
Cdd:TIGR02868 346 GAPPVLDGVSLDLPPGERVaILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVR----RRVSVCAQDAHLF 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   91 EyLSVECNIDLV---LSLSNLNKAERKMKVAKVLEEL--GISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTK 165
Cdd:TIGR02868 422 D-TTVRENLRLArpdATDEELWAALERVGLADWLRALpdGLDTVLGEGGARLSGGERQRLALARALLADAPILLLDEPTE 500

                         170       180
                  ....*....|....*....|....*....
gi 736694016  166 ALDLLAANKIMTELKKIAKERIVIIVTHD 194
Cdd:TIGR02868 501 HLDAETADELLEDLLAALSGRTVVLITHH 529
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 31-211 9.68e-19

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 90.13  E-value: 9.68e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTL----LNIISgmdqnFEGDVYFNNQSMKRFTKKELSDYYyNSIGFIWQDyqliEY------LSVECNID 100
Cdd:COG4172  317 LVGESGSGKSTLglalLRLIP-----SEGEIRFDGQDLDGLSRRALRPLR-RRMQVVFQD----PFgslsprMTVGQIIA 386

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 101 --LVLSLSNLNKAERKMKVAKVLEELGISGLAKMK-VAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMT 177
Cdd:COG4172  387 egLRVHGPGLSAAERRARVAEALEEVGLDPAARHRyPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILD 466

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 736694016 178 ELKKIAKER----IVIivTHDKGLIEKDAN-VYSMEQGQ 211
Cdd:COG4172  467 LLRDLQREHglayLFI--SHDLAVVRALAHrVMVMKDGK 503
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 31-209 9.87e-19

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 84.85  E-value: 9.87e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRftkkeLSDYYYNSIGFIWQDYQLIEYLSVECNIDLvlsLSNLNK 110
Cdd:cd03231   31 VTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDF-----QRDSIARGLLYLGHAPGIKTTLSVLENLRF---WHADHS 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 111 AErkmKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKK-IAKERIVI 189
Cdd:cd03231  103 DE---QVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAGhCARGGMVV 179

                        170       180
                 ....*....|....*....|.
gi 736694016 190 IVTH-DKGLIEKDANVYSMEQ 209
Cdd:cd03231  180 LTTHqDLGLSEAGARELDLGF 200
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
31-194 1.09e-18

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 88.55  E-value: 1.09e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNK 110
Cdd:PRK10070  59 IMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKIAMVFQSFALMPHMTVLDNTAFGMELAGINA 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 111 AERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKI--AKERIV 188
Cdd:PRK10070 139 EERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLqaKHQRTI 218


                 ....*.
gi 736694016 189 IIVTHD 194
Cdd:PRK10070 219 VFISHD 224
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 31-193 1.18e-18

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 84.72  E-value: 1.18e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKrftkkELSDYYYNSIGFIWQDYQLIEYLSVECNIDLvlsLSNLNK 110
Cdd:TIGR01189  31 VTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLA-----EQRDEPHENILYLGHLPGLKPELSALENLHF---WAAIHG 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  111 AERKMkVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKK-IAKERIVI 189
Cdd:TIGR01189 103 GAQRT-IEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVALLAGLLRAhLARGGIVL 181


                  ....
gi 736694016  190 IVTH 193
Cdd:TIGR01189 182 LTTH 185
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 26-226 1.19e-18

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 90.17  E-value: 1.19e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   26 KGLNF---------IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKelsdYYYNSIGFIWQDYQLIEYlSVE 96
Cdd:TIGR00958 498 KGLTFtlhpgevvaLVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHH----YLHRQVALVGQEPVLFSG-SVR 572

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   97 CNIdlvlsLSNLNKAERKMKVAKVLE----------ELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKA 166
Cdd:TIGR00958 573 ENI-----AYGLTDTPDEEIMAAAKAanahdfimefPNGYDTEVGEKGSQLSGGQKQRIAIARALVRKPRVLILDEATSA 647

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  167 LDlLAANKIMTELKKiAKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVGQSKQHSKDDG 226
Cdd:TIGR00958 648 LD-AECEQLLQESRS-RASRTVLLIAHRLSTVERADQILVLKKGSVVEMGTHKQLMEDQG 705
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
2-193 1.30e-18

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 87.17  E-value: 1.30e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyynSI 80
Cdd:PRK13537   8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFgLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQ-----RV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIA 160
Cdd:PRK13537  83 GVVPQFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVL 162

                        170       180       190
                 ....*....|....*....|....*....|....
gi 736694016 161 DEPTKALDLLAANKIMTELKKI-AKERIVIIVTH 193
Cdd:PRK13537 163 DEPTTGLDPQARHLMWERLRSLlARGKTILLTTH 196
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 17-220 2.39e-18

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 85.67  E-value: 2.39e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  17 LNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKrFTKKELSDYYyNSIGFIWQ--DYQLIEyL 93
Cdd:PRK13636  22 LKGININIKKGeVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPID-YSRKGLMKLR-ESVGMVFQdpDNQLFS-A 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  94 SVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAAN 173
Cdd:PRK13636  99 SVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVS 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 736694016 174 KIMTELKKIAKER--IVIIVTHDKGLIEKDA-NVYSMEQGQLKLVGQSKQ 220
Cdd:PRK13636 179 EIMKLLVEMQKELglTIIIATHDIDIVPLYCdNVFVMKEGRVILQGNPKE 228
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 31-226 3.20e-18

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 88.75  E-value: 3.20e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMdQNFEGDVYFNNQsmkrftkkELSD----YYYNSIGFIWQDYQLIEYlSVECNIDL---VL 103
Cdd:PRK11174 381 LVGPSGAGKTSLLNALLGF-LPYQGSLKINGI--------ELREldpeSWRKHLSWVGQNPQLPHG-TLRDNVLLgnpDA 450

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 104 SLSNLNKAERKMKVAKVLEEL--GISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKK 181
Cdd:PRK11174 451 SDEQLQQALENAWVSEFLPLLpqGLDTPIGDQAAGLSVGQAQRLALARALLQPCQLLLLDEPTASLDAHSEQLVMQALNA 530

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 736694016 182 IAKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVGQSKQHSKDDG 226
Cdd:PRK11174 531 ASRRQTTLMVTHQLEDLAQWDQIWVMQDGQIVQQGDYAELSQAGG 575
cbiO PRK13646
energy-coupling factor transporter ATPase;
17-250 4.44e-18

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 85.22  E-value: 4.44e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  17 LNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQ--DYQLIEYl 93
Cdd:PRK13646  23 IHDVNTEFEQGKYYaIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQfpESQLFED- 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  94 SVECNIDLVLSLSNLNKAERKMKVAKVLEELGIS-GLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAA 172
Cdd:PRK13646 102 TVEREIIFGPKNFKMNLDEVKNYAHRLLMDLGFSrDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLDPQSK 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 173 NKIMTELKKIAKE--RIVIIVTHDKGLIEKDA-NVYSMEQGQLKLVGQSKQHSKDDGKNNR--LNKPPYLSLKNCISQSF 247
Cdd:PRK13646 182 RQVMRLLKSLQTDenKTIILVSHDMNEVARYAdEVIVMKEGSIVSQTSPKELFKDKKKLADwhIGLPEIVQLQYDFEQKY 261


                 ...
gi 736694016 248 NIL 250
Cdd:PRK13646 262 QTK 264
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 1-194 4.74e-18

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 84.37  E-value: 4.74e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVF----GNE-IVLNHLSGDFQKGlNF--IYGPSGSGKTTLLNIISG---MDqnfEGDVYFNNQSMKRftkk 70
Cdd:COG1101    1 MLELKNLSKTFnpgtVNEkRALDGLNLTIEEG-DFvtVIGSNGAGKSTLLNAIAGslpPD---SGSILIDGKDVTK---- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  71 eLSDYY-YNSIGFIWQDYQL--IEYLSVECNIDLV--------LSLSnLNKAERKMKVAKvLEELGIsGLA---KMKVAK 136
Cdd:COG1101   73 -LPEYKrAKYIGRVFQDPMMgtAPSMTIEENLALAyrrgkrrgLRRG-LTKKRRELFREL-LATLGL-GLEnrlDTKVGL 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 137 LSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHD 194
Cdd:COG1101  149 LSGGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENnlTTLMVTHN 208
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
3-194 6.30e-18

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 84.43  E-value: 6.30e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   3 SLIEIKKVF---GNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELsdyyYN 78
Cdd:PRK11831   6 NLVDMRGVSftrGNRCIFDNISLTVPRGkITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRL----YT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  79 S---IGFIWQDYQLIEYLSVECNIDLVL-SLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKD 154
Cdd:PRK11831  82 VrkrMSMLFQSGALFTDMNVFDNVAYPLrEHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALE 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 736694016 155 PEIIIADEPTKALDLLAAN---KIMTELKKiAKERIVIIVTHD 194
Cdd:PRK11831 162 PDLIMFDEPFVGQDPITMGvlvKLISELNS-ALGVTCVVVSHD 203
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
1-194 1.02e-17

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 83.24  E-value: 1.02e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDY---- 75
Cdd:COG4559    1 MLEAENLSVRLGGRTLLDDVSLTLRPGeLTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELARRravl 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  76 -YYNSIGFIWqdyqlieylSVEcniDLV----LSLSNLNKAERKMkVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARA 150
Cdd:COG4559   81 pQHSSLAFPF---------TVE---EVValgrAPHGSSAAQDRQI-VREALALVGLAHLAGRSYQTLSGGEQQRVQLARV 147

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 736694016 151 LV-------KDPEIIIADEPTKALDLLAANKIMTELKKIAKERI-VIIVTHD 194
Cdd:COG4559  148 LAqlwepvdGGPRWLFLDEPTSALDLAHQHAVLRLARQLARRGGgVVAVLHD 199
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 11-193 1.10e-17

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 83.29  E-value: 1.10e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  11 FGNEIVLNHLSGDFQ-KGLNFIYGPSGSGKTTLLNIISGM-DQNFE----GDVYFNNQSM--KRFTKKELSdyyyNSIGF 82
Cdd:PRK14239  15 YNKKKALNSVSLDFYpNEITALIGPSGSGKSTLLRSINRMnDLNPEvtitGSIVYNGHNIysPRTDTVDLR----KEIGM 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  83 IWQD-----YQLIEYLSVECNIDLVLSLSNLNKA-ERKMKVAKVLEE----LGISGLAkmkvakLSGGQKQRVAIARALV 152
Cdd:PRK14239  91 VFQQpnpfpMSIYENVVYGLRLKGIKDKQVLDEAvEKSLKGASIWDEvkdrLHDSALG------LSGGQQQRVCIARVLA 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 736694016 153 KDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIVTH 193
Cdd:PRK14239 165 TSPKIILLDEPTSALDPISAGKIEETLLGLKDDYTMLLVTR 205
cbiO PRK13637
energy-coupling factor transporter ATPase;
31-220 1.44e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 83.56  E-value: 1.44e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkrfTKKE--LSDYYyNSIGFIWQ--DYQLIEYlSVECNIDLVLSLS 106
Cdd:PRK13637  38 LIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDI---TDKKvkLSDIR-KKVGLVFQypEYQLFEE-TIEKDIAFGPINL 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 107 NLNKAERKMKVAKVLEELGIS--GLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAK 184
Cdd:PRK13637 113 GLSEEEIENRVKRAMNIVGLDyeDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIKELHK 192

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 736694016 185 ER--IVIIVTHDKGLIEKDAN-VYSMEQGQLKLVGQSKQ 220
Cdd:PRK13637 193 EYnmTIILVSHSMEDVAKLADrIIVMNKGKCELQGTPRE 231
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 31-212 1.69e-17

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 86.31  E-value: 1.69e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQL--------IEYLS----VECN 98
Cdd:TIGR02203 363 LVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLASLR----RQVALVSQDVVLfndtiannIAYGRteqaDRAE 438

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   99 IDLVLSLSNLNKAERKMkvakvleELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTE 178
Cdd:TIGR02203 439 IERALAAAYAQDFVDKL-------PLGLDTPIGENGVLLSGGQRQRLAIARALLKDAPILILDEATSALDNESERLVQAA 511

                         170       180       190
                  ....*....|....*....|....*....|....
gi 736694016  179 LKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:TIGR02203 512 LERLMQGRTTLVIAHRLSTIEKADRIVVMDDGRI 545
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 2-193 1.91e-17

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 80.17  E-value: 1.91e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQsmkrftkkelsdyyynsi 80
Cdd:cd03216    1 LELRGITKRFGGVKALDGVSLSVRRGeVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGK------------------ 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 gfiwqdyqlieylsvecnidlVLSLSNLNKAERkmkvakvleeLGISglakMkVAKLSGGQKQRVAIARALVKDPEIIIA 160
Cdd:cd03216   63 ---------------------EVSFASPRDARR----------AGIA----M-VYQLSVGERQMVEIARALARNARLLIL 106

                        170       180       190
                 ....*....|....*....|....*....|....
gi 736694016 161 DEPTKALDLLAANKIMTELKKIAKERI-VIIVTH 193
Cdd:cd03216  107 DEPTAALTPAEVERLFKVIRRLRAQGVaVIFISH 140
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 1-193 1.91e-17

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 85.85  E-value: 1.91e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-----LnfiyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkRFtkkelsdy 75
Cdd:COG3845    5 ALELRGITKRFGGVVANDDVSLTVRPGeihalL----GENGAGKSTLMKILYGLYQPDSGEILIDGKPV-RI-------- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  76 yyNS--------IGFIWQDYQLIEYLSVECNIdlVLSLSNLN------KAERKmKVAKVLEELGISGLAKMKVAKLSGGQ 141
Cdd:COG3845   72 --RSprdaialgIGMVHQHFMLVPNLTVAENI--VLGLEPTKggrldrKAARA-RIRELSERYGLDVDPDAKVEDLSVGE 146

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 736694016 142 KQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTH 193
Cdd:COG3845  147 QQRVEILKALYRGARILILDEPTAVLTPQEADELFEILRRLAAEgKSIIFITH 199
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 28-198 2.26e-17

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 83.62  E-value: 2.26e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  28 LNF---------IYGPSGSGKT-TLLNIISGMDQN--FEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQD--YQLIEYL 93
Cdd:PRK09473  35 LNFslragetlgIVGESGSGKSqTAFALMGLLAANgrIGGSATFNGREILNLPEKELNKLRAEQISMIFQDpmTSLNPYM 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  94 SVECNIDLVLSL-SNLNKAERKMKVAKVLEELGISGLAK---MKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDL 169
Cdd:PRK09473 115 RVGEQLMEVLMLhKGMSKAEAFEESVRMLDAVKMPEARKrmkMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDV 194

                        170       180       190
                 ....*....|....*....|....*....|.
gi 736694016 170 LAANKIMTELKKIAKE--RIVIIVTHDKGLI 198
Cdd:PRK09473 195 TVQAQIMTLLNELKREfnTAIIMITHDLGVV 225
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 31-249 4.05e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 82.38  E-value: 4.05e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYF---------NNQSMKRFTKKelsdyyynsIGFIWQ--DYQLIEYlSVECNI 99
Cdd:PRK13634  38 IIGHTGSGKSTLLQHLNGLLQPTSGTVTIgervitagkKNKKLKPLRKK---------VGIVFQfpEHQLFEE-TVEKDI 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 100 dlvlSLSNLN----KAERKMKVAKVLEELGISG--LAKMKVAkLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAAN 173
Cdd:PRK13634 108 ----CFGPMNfgvsEEDAKQKAREMIELVGLPEelLARSPFE-LSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKGRK 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 174 KIMTELKKIAKER--IVIIVTHDKglieKDANVYS-----MEQGQLKLVGQSKQ--HSKDDGKNNRLNKPPYLSLKNCIS 244
Cdd:PRK13634 183 EMMEMFYKLHKEKglTTVLVTHSM----EDAARYAdqivvMHKGTVFLQGTPREifADPDELEAIGLDLPETVKFKRALE 258


                 ....*
gi 736694016 245 QSFNI 249
Cdd:PRK13634 259 EKFGI 263
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
1-217 4.23e-17

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 81.98  E-value: 4.23e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQK-GLNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKrFTKKELSDYYyNS 79
Cdd:PRK13638   1 MLATSDLWFRYQDEPVLKGLNLDFSLsPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLD-YSKRGLLALR-QQ 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQD-YQLIEYLSVECniDLVLSLSNLNKAERKM--KVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPE 156
Cdd:PRK13638  79 VATVFQDpEQQIFYTDIDS--DIAFSLRNLGVPEAEItrRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQAR 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 736694016 157 IIIADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTHDKGLI-EKDANVYSMEQGQLKLVGQ 217
Cdd:PRK13638 157 YLLLDEPTAGLDPAGRTQMIAIIRRIVAQgNHVIISSHDIDLIyEISDAVYVLRQGQILTHGA 219
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
31-194 4.69e-17

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 84.86  E-value: 4.69e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISG-MDQNFeGDvYFNNQS----MKRFTKKELSDY----YYNSIGFIwQDYQLIEYL------SV 95
Cdd:PRK13409 104 ILGPNGIGKTTAVKILSGeLIPNL-GD-YEEEPSwdevLKRFRGTELQNYfkklYNGEIKVV-HKPQYVDLIpkvfkgKV 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  96 EcniDLvlslsnLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALD----LLA 171
Cdd:PRK13409 181 R---EL------LKKVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDirqrLNV 251

                        170       180
                 ....*....|....*....|...
gi 736694016 172 ANKImtelKKIAKERIVIIVTHD 194
Cdd:PRK13409 252 ARLI----RELAEGKYVLVVEHD 270
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 13-212 5.09e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 82.59  E-value: 5.09e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  13 NEI-VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNS----------- 79
Cdd:PRK13631  37 NELvALNNISYTFEKNkIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIYIGDKKNNHELITNPYSkkiknfkelrr 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 -IGFIWQ--DYQLIEYlSVECNIDLVLSLSNLNKAERKMKVAKVLEELGI-SGLAKMKVAKLSGGQKQRVAIARALVKDP 155
Cdd:PRK13631 117 rVSMVFQfpEYQLFKD-TIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLdDSYLERSPFGLSGGQKRRVAIAGILAIQP 195

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 156 EIIIADEPTKALDlLAANKIMTELKKIAKE--RIVIIVTHD-KGLIEKDANVYSMEQGQL 212
Cdd:PRK13631 196 EILIFDEPTAGLD-PKGEHEMMQLILDAKAnnKTVFVITHTmEHVLEVADEVIVMDKGKI 254
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 16-211 9.98e-17

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 79.05  E-value: 9.98e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  16 VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISG-MDQNfEGDVYFNNqsmkrftkkelsdyyynSIGFI----Wqdyql 89
Cdd:cd03250   20 TLKDINLEVPKGeLVAIVGPVGSGKSSLLSALLGeLEKL-SGSVSVPG-----------------SIAYVsqepW----- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  90 IEYLSVECNIdlvLSLSNLNKaERKMKVAKV--LE------------ELGISGLAkmkvakLSGGQKQRVAIARALVKDP 155
Cdd:cd03250   77 IQNGTIRENI---LFGKPFDE-ERYEKVIKAcaLEpdleilpdgdltEIGEKGIN------LSGGQKQRISLARAVYSDA 146

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 156 EIIIADEPTKALDLLAANKIMTE--LKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQ 211
Cdd:cd03250  147 DIYLLDDPLSAVDAHVGRHIFENciLGLLLNNKTRILVTHQLQLLPHADQIVVLDNGR 204
cbiO PRK13650
energy-coupling factor transporter ATPase;
1-212 1.28e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 80.55  E-value: 1.28e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVF------GNEIVLNHLSGDFQKG--LNFIyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQsmkRFTKKEL 72
Cdd:PRK13650   1 MSNIIEVKNLTfkykedQEKYTLNDVSFHVKQGewLSII-GHNGSGKSTTVRLIDGLLEAESGQIIIDGD---LLTEENV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  73 SDYYYNsIGFIWQ--DYQLIEyLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARA 150
Cdd:PRK13650  77 WDIRHK-IGMVFQnpDNQFVG-ATVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGA 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 736694016 151 LVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:PRK13650 155 VAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYqmTVISITHDLDEVALSDRVLVMKNGQV 218
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
1-189 2.25e-16

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 82.52  E-value: 2.25e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKelsDYYYNS 79
Cdd:PRK09700   5 YISMAGIGKSFGPVHALKSVNLTVYPGeIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHK---LAAQLG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNIDL-------VLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALV 152
Cdd:PRK09700  82 IGIIYQELSVIDELTVLENLYIgrhltkkVCGVNIIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLM 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 736694016 153 KDPEIIIADEPTKAL-----DLLAAnkIMTELKKIAKERIVI 189
Cdd:PRK09700 162 LDAKVIIMDEPTSSLtnkevDYLFL--IMNQLRKEGTAIVYI 201
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 33-220 2.49e-16

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 78.87  E-value: 2.49e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDyyyNSIGFIWQDYQLIEYLSVECNIDLVLSLSNlNKAE 112
Cdd:COG0410   36 GRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIAR---LGIGYVPEGRRIFPSLTVEENLLLGAYARR-DRAE 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 113 RKMKVAKVLEELGIsgLAKM---KVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVI 189
Cdd:COG0410  112 VRADLERVYELFPR--LKERrrqRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNREGVTI 189

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 736694016 190 IvthdkgLIEKDAN--------VYSMEQGQLKLVGQSKQ 220
Cdd:COG0410  190 L------LVEQNARfaleiadrAYVLERGRIVLEGTAAE 222
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 2-211 2.64e-16

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 75.95  E-value: 2.64e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVyfnnQSMKRFTkkelsdyyynsI 80
Cdd:cd03221    1 IELENLSKTYGGKLLLKDISLTINPGDRIgLVGRNGAGKSTLLKLIAGELEPDEGIV----TWGSTVK-----------I 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQdyqlieylsvecnidlvlslsnlnkaerkmkvakvleelgisglakmkvakLSGGQKQRVAIARALVKDPEIIIA 160
Cdd:cd03221   66 GYFEQ---------------------------------------------------LSGGEKMRLALAKLLLENPNLLLL 94

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 736694016 161 DEPTKALDLLAANKIMTELKKiaKERIVIIVTHDKGLIEKDAN-VYSMEQGQ 211
Cdd:cd03221   95 DEPTNHLDLESIEALEEALKE--YPGTVILVSHDRYFLDQVATkIIELEDGK 144
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 31-220 2.71e-16

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 80.56  E-value: 2.71e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKT-TLLNIISGMDqnFEGDVY-----FNNQSMKRFTKKELSDYYYNSIGFIWQD------------YQLIEY 92
Cdd:PRK11022  38 IVGESGSGKSvSSLAIMGLID--YPGRVMaekleFNGQDLQRISEKERRNLVGAEVAMIFQDpmtslnpcytvgFQIMEA 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  93 LSVEcnidlvlslSNLNKAERKMKVAKVLEELGISGLA-KMKV--AKLSGGQKQRVAIARALVKDPEIIIADEPTKALDL 169
Cdd:PRK11022 116 IKVH---------QGGNKKTRRQRAIDLLNQVGIPDPAsRLDVypHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALDV 186

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 170 LAANKIMT---ELKKiaKERI-VIIVTHDKGLIEKDAN-VYSMEQGQLKLVGQSKQ 220
Cdd:PRK11022 187 TIQAQIIElllELQQ--KENMaLVLITHDLALVAEAAHkIIVMYAGQVVETGKAHD 240
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 31-194 3.94e-16

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 81.77  E-value: 3.94e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFN------NQSMKRFTKKELSDYYynsIGFIWQDYQLIEYLSVECNIDLVLS 104
Cdd:TIGR03269 315 IVGTSGAGKTTLSKIIAGVLEPTSGEVNVRvgdewvDMTKPGPDGRGRAKRY---IGILHQEYDLYPHRTVLDNLTEAIG 391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  105 LS-----NLNKAERKMKVAKVLEELGISGLAKMKvAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTEL 179
Cdd:TIGR03269 392 LElpdelARMKAVITLKMVGFDEEKAEEILDKYP-DELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSI 470

                         170
                  ....*....|....*..
gi 736694016  180 KKIAKE--RIVIIVTHD 194
Cdd:TIGR03269 471 LKAREEmeQTFIIVSHD 487
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 4-212 4.53e-16

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 81.79  E-value: 4.53e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   4 LIEIKKV-FG----NEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIIS-GMDQNfEGDVYFNNQSMKRFTKKELSdyy 76
Cdd:PRK11160 338 SLTLNNVsFTypdqPQPVLKGLSLQIKAGEKVaLLGRTGCGKSTLLQLLTrAWDPQ-QGEILLNGQPIADYSEAALR--- 413

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  77 yNSIGFIWQDYQLieyLSVECNIDLVLSLSNLNKAerkmKVAKVLEELGISGLAKMKVA----------KLSGGQKQRVA 146
Cdd:PRK11160 414 -QAISVVSQRVHL---FSATLRDNLLLAAPNASDE----ALIEVLQQVGLEKLLEDDKGlnawlgeggrQLSGGEQRRLG 485

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 147 IARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:PRK11160 486 IARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQNKTVLMITHRLTGLEQFDRICVMDNGQI 551
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 26-193 4.62e-16

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 81.79  E-value: 4.62e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  26 KGLNF---------IYGPSGSGKTTLLNIISGM-DQNfEGDVYFNNQSMKRFTKKELSDyyynSIGFIWQDYQL----IE 91
Cdd:COG5265  375 KGVSFevpagktvaIVGPSGAGKSTLARLLFRFyDVT-SGRILIDGQDIRDVTQASLRA----AIGIVPQDTVLfndtIA 449

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  92 YlsvecNI----------------------DLVLSLSNLNKA---ERkmkvakvleelgisGLakmkvaKLSGGQKQRVA 146
Cdd:COG5265  450 Y-----NIaygrpdaseeeveaaaraaqihDFIESLPDGYDTrvgER--------------GL------KLSGGEKQRVA 504

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 736694016 147 IARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIVTH 193
Cdd:COG5265  505 IARTLLKNPPILIFDEATSALDSRTERAIQAALREVARGRTTLVIAH 551
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 31-194 5.73e-16

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 81.37  E-value: 5.73e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISG-MDQNFeGDvyFNNQS-----MKRFTKKELSDY----YYNSIGFIwQDYQLIEYLS--VECN 98
Cdd:COG1245  104 ILGPNGIGKSTALKILSGeLKPNL-GD--YDEEPswdevLKRFRGTELQDYfkklANGEIKVA-HKPQYVDLIPkvFKGT 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  99 I-DLvlslsnLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDL---LAANK 174
Cdd:COG1245  180 VrEL------LEKVDERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLDIyqrLNVAR 253

                        170       180
                 ....*....|....*....|
gi 736694016 175 IMTELKKiaKERIVIIVTHD 194
Cdd:COG1245  254 LIRELAE--EGKYVLVVEHD 271
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 33-168 6.08e-16

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 79.39  E-value: 6.08e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNsIGFIWQDyqlieylsvecnidlvlSLSNLNkae 112
Cdd:COG4608   51 GESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSGRELRPLRRR-MQMVFQD-----------------PYASLN--- 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 113 RKMKVAKVLEE-LGISGLA-----KMKVAKL------------------SGGQKQRVAIARALVKDPEIIIADEPTKALD 168
Cdd:COG4608  110 PRMTVGDIIAEpLRIHGLAskaerRERVAELlelvglrpehadryphefSGGQRQRIGIARALALNPKLIVCDEPVSALD 189
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
2-193 6.65e-16

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 79.49  E-value: 6.65e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQ---SMKRFTKKElsdyyy 77
Cdd:PRK13536  42 IDLAGVSKSYGDKAVVNGLSFTVASGECFgLLGPNGAGKSTIARMILGMTSPDAGKITVLGVpvpARARLARAR------ 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  78 nsIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEI 157
Cdd:PRK13536 116 --IGVVPQFDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQL 193

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 736694016 158 IIADEPTKALDLLAANKIMTELKK-IAKERIVIIVTH 193
Cdd:PRK13536 194 LILDEPTTGLDPHARHLIWERLRSlLARGKTILLTTH 230
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 33-211 8.31e-16

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 80.90  E-value: 8.31e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKT-TLLNII----SGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQD--YQLIEYLSVECNIDLVLSL 105
Cdd:PRK15134  42 GESGSGKSvTALSILrllpSPPVVYPSGDIRFHGESLLHASEQTLRGVRGNKIAMIFQEpmVSLNPLHTLEKQLYEVLSL 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 106 -SNLNKAERKMKVAKVLEELGISGLAKmKVA----KLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELK 180
Cdd:PRK15134 122 hRGMRREAARGEILNCLDRVGIRQAAK-RLTdyphQLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLR 200

                        170       180       190
                 ....*....|....*....|....*....|....
gi 736694016 181 KIAKE--RIVIIVTHDKGLIEKDA-NVYSMEQGQ 211
Cdd:PRK15134 201 ELQQElnMGLLFITHNLSIVRKLAdRVAVMQNGR 234
PLN03211 PLN03211
ABC transporter G-25; Provisional
 31-207 8.38e-16

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 81.08  E-value: 8.38e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQ--NFEGDVYFNNQSMKRFTKKElsdyyynsIGFIWQDYQLIEYLSVECNIDLV--LSLS 106
Cdd:PLN03211  99 VLGPSGSGKSTLLNALAGRIQgnNFTGTILANNRKPTKQILKR--------TGFVTQDDILYPHLTVRETLVFCslLRLP 170

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 107 N-LNKAERKMKVAKVLEELGISGLAKMKVAK-----LSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELK 180
Cdd:PLN03211 171 KsLTKQEKILVAESVISELGLTKCENTIIGNsfirgISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLG 250

                        170       180
                 ....*....|....*....|....*...
gi 736694016 181 KIA-KERIVIIVTHdkgliEKDANVYSM 207
Cdd:PLN03211 251 SLAqKGKTIVTSMH-----QPSSRVYQM 273
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
11-194 8.64e-16

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 77.72  E-value: 8.64e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  11 FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQL 89
Cdd:PRK10253  17 YGKYTVAENLTVEIPDGhFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVA----RRIGLLAQNATT 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  90 IEYLSVEcniDLVLS-------LSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADE 162
Cdd:PRK10253  93 PGDITVQ---ELVARgryphqpLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDE 169

                        170       180       190
                 ....*....|....*....|....*....|....
gi 736694016 163 PTKALDLLAANKIMTELKKIAKER--IVIIVTHD 194
Cdd:PRK10253 170 PTTWLDISHQIDLLELLSELNREKgyTLAAVLHD 203
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
1-193 1.08e-15

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 76.00  E-value: 1.08e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRftkkeLSDYYYNS 79
Cdd:PRK13538   1 MLEARNLACERDERILFSGLSFTLNAGeLVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRR-----QRDEYHQD 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERkmkVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:PRK13538  76 LLYLGHQPGIKTELTALENLRFYQRLHGPGDDEA---LWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWI 152

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 736694016 160 ADEPTKALDlLAANKIMTEL--KKIAKERIVIIVTH 193
Cdd:PRK13538 153 LDEPFTAID-KQGVARLEALlaQHAEQGGMVILTTH 187
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 1-193 1.38e-15

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 76.07  E-value: 1.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGD-FQKGLNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYyyns 79
Cdd:PRK13539   2 MLEGEDLACVRGGRVLFSGLSFTlAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEACHY---- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFiwQDYqLIEYLSVECNIDLvlsLSNLNKAERKMkVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:PRK13539  78 LGH--RNA-MKPALTVAENLEF---WAAFLGGEELD-IAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWI 150

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 736694016 160 ADEPTKALDlLAANKIMTELKKIAKER--IVIIVTH 193
Cdd:PRK13539 151 LDEPTAALD-AAAVALFAELIRAHLAQggIVIAATH 185
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
31-212 2.78e-15

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 76.37  E-value: 2.78e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkrftkkELSDYYYNS--IGFIWQD-------YQLIEYLsvecnIDL 101
Cdd:PRK15112  44 IIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPL------HFGDYSYRSqrIRMIFQDpstslnpRQRISQI-----LDF 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 102 VLSL-SNLNKAERKMKVAKVLEELGI-SGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKI---M 176
Cdd:PRK15112 113 PLRLnTDLEPEQREKQIIETLRQVGLlPDHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLinlM 192

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 736694016 177 TELKKiaKERIVII-VTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:PRK15112 193 LELQE--KQGISYIyVTQHLGMMKHISDqVLVMHQGEV 228
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 11-194 2.88e-15

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 76.67  E-value: 2.88e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  11 FGNEIVLNHLSGDF-QKGLNFIYGPSGSGKTTLLNIISGMDQN-----FEGDVYFNNQSMkrFTKKELSDYYyNSIGFIW 84
Cdd:PRK14271  31 FAGKTVLDQVSMGFpARAVTSLMGPTGSGKTTFLRTLNRMNDKvsgyrYSGDVLLGGRSI--FNYRDVLEFR-RRVGMLF 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  85 QDYQLIEyLSVECNIDLVLSLSNLNKAERKMKVAKV-LEELGISGLAKMKVA----KLSGGQKQRVAIARALVKDPEIII 159
Cdd:PRK14271 108 QRPNPFP-MSIMDNVLAGVRAHKLVPRKEFRGVAQArLTEVGLWDAVKDRLSdspfRLSGGQQQLLCLARTLAVNPEVLL 186

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAKERIVIIVTHD 194
Cdd:PRK14271 187 LDEPTSALDPTTTEKIEEFIRSLADRLTVIIVTHN 221
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
2-193 3.84e-15

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 78.41  E-value: 3.84e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   2 LSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkRFTkkELSDYYYNSI 80
Cdd:PRK11288   5 LSFDGIGKTFPGVKALDDISFDCRAGqVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEM-RFA--STTAALAAGV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQDYQLIEYLSVECNI---DLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEI 157
Cdd:PRK11288  82 AIIYQELHLVPEMTVAENLylgQLPHKGGIVNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARV 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 736694016 158 IIADEPTKAL-----DLLAanKIMTELKkiAKERIVIIVTH 193
Cdd:PRK11288 162 IAFDEPTSSLsareiEQLF--RVIRELR--AEGRVILYVSH 198
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 25-193 4.82e-15

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 75.26  E-value: 4.82e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  25 QKGLNFIYGPSGSGKTTLLNIISGM-----DQNFEGDVYFNNQSMkrFTKKELSDYYYNSIGFIWQDYQLIEYLSVECNI 99
Cdd:PRK14267  29 QNGVFALMGPSGCGKSTLLRTFNRLlelneEARVEGEVRLFGRNI--YSPDVDPIEVRREVGMVFQYPNPFPHLTIYDNV 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 100 DLVLSLSNLNKAERK--------MKVAKVLEElgISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLA 171
Cdd:PRK14267 107 AIGVKLNGLVKSKKEldervewaLKKAALWDE--VKDRLNDYPSNLSGGQRQRLVIARALAMKPKILLMDEPTANIDPVG 184

                        170       180
                 ....*....|....*....|..
gi 736694016 172 ANKIMTELKKIAKERIVIIVTH 193
Cdd:PRK14267 185 TAKIEELLFELKKEYTIVLVTH 206
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 30-194 6.88e-15

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 75.20  E-value: 6.88e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  30 FIyGPSGSGKTTLLNIISGMDQ-----NFEGDVYFNNQSM--KRFTKKELSdyyyNSIGFIWQD--------YQLIEY-- 92
Cdd:PRK14243  41 FI-GPSGCGKSTILRCFNRLNDlipgfRVEGKVTFHGKNLyaPDVDPVEVR----RRIGMVFQKpnpfpksiYDNIAYga 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  93 --LSVECNIDLVLslsnlnkaERKMKVA----KVLEELGISGLAkmkvakLSGGQKQRVAIARALVKDPEIIIADEPTKA 166
Cdd:PRK14243 116 riNGYKGDMDELV--------ERSLRQAalwdEVKDKLKQSGLS------LSGGQQQRLCIARAIAVQPEVILMDEPCSA 181

                        170       180
                 ....*....|....*....|....*...
gi 736694016 167 LDLLAANKIMTELKKIAKERIVIIVTHD 194
Cdd:PRK14243 182 LDPISTLRIEELMHELKEQYTIIIVTHN 209
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 31-206 9.20e-15

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 75.51  E-value: 9.20e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNS--------------------IGFIWQ--DYQ 88
Cdd:PRK13651  38 IIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNKKKTKEKEKVLEKlviqktrfkkikkikeirrrVGVVFQfaEYQ 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  89 LIEYlSVECNIDLVLSLSNLNKAERKMKVAKVLEELG--ISGLAKMKVAkLSGGQKQRVAIARALVKDPEIIIADEPTKA 166
Cdd:PRK13651 118 LFEQ-TIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGldESYLQRSPFE-LSGGQKRRVALAGILAMEPDFLVFDEPTAG 195

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 167 LDLLAANKIMTELKKIAKE-RIVIIVTHD---------------KGLIEKDANVYS 206
Cdd:PRK13651 196 LDPQGVKEILEIFDNLNKQgKTIILVTHDldnvlewtkrtiffkDGKIIKDGDTYD 251
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 31-191 1.27e-14

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 72.46  E-value: 1.27e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDyyyNSIGFIWQDYQ---LIEYLSVECNIdlvlSLSN 107
Cdd:cd03215   31 IAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAIR---AGIAYVPEDRKregLVLDLSVAENI----ALSS 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 108 LnkaerkmkvakvleelgisglakmkvakLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERI 187
Cdd:cd03215  104 L----------------------------LSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADAGK 155


                 ....
gi 736694016 188 VIIV 191
Cdd:cd03215  156 AVLL 159
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
13-220 1.33e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 74.74  E-value: 1.33e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  13 NEIVLNHLSGDFQKGlNF--IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNqsmkrFTKKELSDYY--YNSIGFIWQ--D 86
Cdd:PRK13633  22 EKLALDDVNLEVKKG-EFlvILGRNGSGKSTIAKHMNALLIPSEGKVYVDG-----LDTSDEENLWdiRNKAGMVFQnpD 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  87 YQLIEYLSVEcniDLVLSLSNLN--KAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPT 164
Cdd:PRK13633  96 NQIVATIVEE---DVAFGPENLGipPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPT 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 736694016 165 KALDLLAANKIMTELKKIAKER--IVIIVTHdkgLIEKDAN---VYSMEQGQLKLVGQSKQ 220
Cdd:PRK13633 173 AMLDPSGRREVVNTIKELNKKYgiTIILITH---YMEEAVEadrIIVMDSGKVVMEGTPKE 230
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 1-194 1.50e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 74.39  E-value: 1.50e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVF-----GNEiVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSd 74
Cdd:PRK13647   1 MDNIIEVEDLHfrykdGTK-ALKGLSLSIPEGSKTaLLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVR- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  75 yyyNSIGFIWQDY--QLIEYLSVEcniDLVLSLSN--LNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARA 150
Cdd:PRK13647  79 ---SKVGLVFQDPddQVFSSTVWD---DVAFGPVNmgLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGV 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 736694016 151 LVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTHD 194
Cdd:PRK13647 153 LAMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQgKTVIVATHD 197
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 4-213 1.83e-14

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 76.26  E-value: 1.83e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   4 LIEIKKV---FGNEIVLNHLSGDFQKG--LNFIyGPSGSGKTTLLNIISGMDQNFEGDVyfnnqsmKRFTKKELSdyYYN 78
Cdd:COG0488  315 VLELEGLsksYGDKTLLDDLSLRIDRGdrIGLI-GPNGAGKSTLLKLLAGELEPDSGTV-------KLGETVKIG--YFD 384

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  79 sigfiwqdyQLIEYLSVecNIDLVLSLSNLNKAERKMKVAKVLEELGISG-LAKMKVAKLSGGQKQRVAIARALVKDPEI 157
Cdd:COG0488  385 ---------QHQEELDP--DKTVLDELRDGAPGGTEQEVRGYLGRFLFSGdDAFKPVGVLSGGEKARLALAKLLLSPPNV 453

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 736694016 158 IIADEPTKALDLlaankimtELKKIAKERI------VIIVTHDKGLIEKDAN-VYSMEQGQLK 213
Cdd:COG0488  454 LLLDEPTNHLDI--------ETLEALEEALddfpgtVLLVSHDRYFLDRVATrILEFEDGGVR 508
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 33-182 2.65e-14

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 73.00  E-value: 2.65e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTkkeLSDYYYNSIGFIWQDYQLIEYLSVECNIDLVLSL-SNLNKA 111
Cdd:PRK10895  36 GPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLP---LHARARRGIGYLPQEASIFRRLSVYDNLMAVLQIrDDLSAE 112

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 736694016 112 ERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAankiMTELKKI 182
Cdd:PRK10895 113 QREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPIS----VIDIKRI 179
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
31-226 3.00e-14

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 75.90  E-value: 3.00e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYY--YNSIGFIWQDyqlieylSVECNIDLVLSLSNL 108
Cdd:PRK10789 346 ICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWRSRLavVSQTPFLFSD-------TVANNIALGRPDATQ 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 109 NKAERKMKVAKVLE-----------ELGISGLAkmkvakLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMT 177
Cdd:PRK10789 419 QEIEHVARLASVHDdilrlpqgydtEVGERGVM------LSGGQKQRISIARALLLNAEILILDDALSAVDGRTEHQILH 492

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 736694016 178 ELKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVGQSKQHSKDDG 226
Cdd:PRK10789 493 NLRQWGEGRTVIISAHRLSALTEASEILVMQHGHIAQRGNHDQLAQQSG 541
cbiO PRK13649
energy-coupling factor transporter ATPase;
30-220 4.14e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 73.24  E-value: 4.14e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  30 FIyGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQ--DYQLIEYLSVEcniDLVLSLSN 107
Cdd:PRK13649  38 FI-GHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIKQIRKKVGLVFQfpESQLFEETVLK---DVAFGPQN 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 108 LNKAERKmKVAKVLEELGISGLAKMKVAK----LSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIA 183
Cdd:PRK13649 114 FGVSQEE-AEALAREKLALVGISESLFEKnpfeLSGGQMRRVAIAGILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLH 192

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 736694016 184 KERIVII-VTHdkgLIEKDAN----VYSMEQGQLKLVGQSKQ 220
Cdd:PRK13649 193 QSGMTIVlVTH---LMDDVANyadfVYVLEKGKLVLSGKPKD 231
cbiO PRK13640
energy-coupling factor transporter ATPase;
33-194 4.70e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 72.91  E-value: 4.70e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGM---DQNFEGDVYFNNQSMKRFTKKELSDyyynSIGFIWQ--DYQlieYLSVECNIDLVLSLSN 107
Cdd:PRK13640  40 GHNGSGKSTISKLINGLllpDDNPNSKITVDGITLTAKTVWDIRE----KVGIVFQnpDNQ---FVGATVGDDVAFGLEN 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 108 LNKAERKMK--VAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE 185
Cdd:PRK13640 113 RAVPRPEMIkiVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKK 192

                        170
                 ....*....|.
gi 736694016 186 R--IVIIVTHD 194
Cdd:PRK13640 193 NnlTVISITHD 203
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 31-220 4.92e-14

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 72.39  E-value: 4.92e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFE------GDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQLIEYLSVECNIDLVLS 104
Cdd:PRK14246  41 IMGPSGSGKSTLLKVLNRLIEIYDskikvdGKVLYFGKDIFQIDAIKLR----KEVGMVFQQPNPFPHLSIYDNIAYPLK 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 105 LSNLnkaERKMKVAKVLEE-LGISGLAK-------MKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIM 176
Cdd:PRK14246 117 SHGI---KEKREIKKIVEEcLRKVGLWKevydrlnSPASQLSGGQQQRLTIARALALKPKVLLMDEPTSMIDIVNSQAIE 193

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 736694016 177 TELKKIAKERIVIIVTHDKGLIEKDAN-VYSMEQGQLKLVGQSKQ 220
Cdd:PRK14246 194 KLITELKNEIAIVIVSHNPQQVARVADyVAFLYNGELVEWGSSNE 238
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
31-212 7.89e-14

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 74.61  E-value: 7.89e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNI-------------ISGMDQNfegDVyfNNQSMKRftkkelsdyyynSIGFIWQDYQLIEYlSVEC 97
Cdd:PRK13657 366 IVGPTGAGKSTLINLlqrvfdpqsgrilIDGTDIR---TV--TRASLRR------------NIAVVFQDAGLFNR-SIED 427

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  98 NIDLVLSLSNLNKAERKMKVAKVLE-----ELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAA 172
Cdd:PRK13657 428 NIRVGRPDATDEEMRAAAERAQAHDfierkPDGYDTVVGERGRQLSGGERQRLAIARALLKDPPILILDEATSALDVETE 507

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 736694016 173 NKIMTELKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:PRK13657 508 AKVKAALDELMKGRTTFIIAHRLSTVRNADRILVFDNGRV 547
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 1-195 9.86e-14

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 70.36  E-value: 9.86e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkrftKKELSDyYYNS 79
Cdd:PRK13540   1 MLDVIELDFDYHDQPLLQQISFHLPAGgLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSI----KKDLCT-YQKQ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVE--CNIDLVLSLSNlnkaerkMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEI 157
Cdd:PRK13540  76 LCFVGHRSGINPYLTLRenCLYDIHFSPGA-------VGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKL 148

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 736694016 158 IIADEPTKALDLLAANKIMTELKK-IAKERIVIIVTHDK 195
Cdd:PRK13540 149 WLLDEPLVALDELSLLTIITKIQEhRAKGGAVLLTSHQD 187
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 26-212 1.23e-13

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 71.76  E-value: 1.23e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  26 KGLNFI---------YGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYyynsIGFIWQ--DYQLIEyLS 94
Cdd:PRK13652  21 NNINFIaprnsriavIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKF----VGLVFQnpDDQIFS-PT 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  95 VECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANK 174
Cdd:PRK13652  96 VEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKE 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 736694016 175 IMTELKKIAKE--RIVIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:PRK13652 176 LIDFLNDLPETygMTVIFSTHQLDLVPEMADyIYVMDKGRI 216
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 20-212 1.42e-13

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 71.02  E-value: 1.42e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  20 LSGDFQKG--LNFIyGPSGSGKTTLLNIISGMDQnFEGDVYFNNQSMKRFTKKELSDY--YY---NSIGFIWQDYQlieY 92
Cdd:COG4138   15 ISAQVNAGelIHLI-GPNGAGKSTLLARMAGLLP-GQGEILLNGRPLSDWSAAELARHraYLsqqQSPPFAMPVFQ---Y 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  93 LSvecnidlvLSL-SNLNKAERKMKVAKVLEELGISG-LAKMkVAKLSGGQKQRVAIARALVK-DPEI------IIADEP 163
Cdd:COG4138   90 LA--------LHQpAGASSEAVEQLLAQLAEALGLEDkLSRP-LTQLSGGEWQRVRLAAVLLQvWPTInpegqlLLLDEP 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 736694016 164 TKALDL---LAANKIMTELKkiAKERIVIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:COG4138  161 MNSLDVaqqAALDRLLRELC--QQGITVVMSSHDLNHTLRHADrVWLLKQGKL 211
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
17-220 1.49e-13

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 71.58  E-value: 1.49e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  17 LNHLSGDFQKG--LNfIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQ--DYQLIEy 92
Cdd:PRK13635  23 LKDVSFSVYEGewVA-IVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWDVR----RQVGMVFQnpDNQFVG- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  93 LSVEcnIDLVLSLSNlNKAERKMKVAKV---LEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDL 169
Cdd:PRK13635  97 ATVQ--DDVAFGLEN-IGVPREEMVERVdqaLRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDP 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 170 LAANKIMTELKKIAKER--IVIIVTHDkglIEKDAN---VYSMEQGQLKLVGQSKQ 220
Cdd:PRK13635 174 RGRREVLETVRQLKEQKgiTVLSITHD---LDEAAQadrVIVMNKGEILEEGTPEE 226
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 31-225 1.54e-13

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 70.63  E-value: 1.54e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSmkrFTKKELSDYYYNSIGFIWQDYQLIEYLSVECNIDLVLSlsNLNK 110
Cdd:TIGR03410  31 VLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGED---ITKLPPHERARAGIAYVPQGREIFPRLTVEENLLTGLA--ALPR 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  111 AERKMkVAKVLEELGIsgLAKMKVAK---LSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERI 187
Cdd:TIGR03410 106 RSRKI-PDEIYELFPV--LKEMLGRRggdLSGGQQQQLAIARALVTRPKLLLLDEPTEGIQPSIIKDIGRVIRRLRAEGG 182

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 736694016  188 VIIVthdkgLIE------KDA--NVYSMEQGQLKLVGQSKQHSKDD 225
Cdd:TIGR03410 183 MAIL-----LVEqyldfaRELadRYYVMERGRVVASGAGDELDEDK 223
cbiO PRK13643
energy-coupling factor transporter ATPase;
31-212 1.98e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 71.30  E-value: 1.98e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQ--DYQLIEYLSVEcniDLVLSLSN- 107
Cdd:PRK13643  37 LIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKEIKPVRKKVGVVFQfpESQLFEETVLK---DVAFGPQNf 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 108 -LNKAERKMKVAKVLEELGISG-LAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE 185
Cdd:PRK13643 114 gIPKEKAEKIAAEKLEMVGLADeFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKARIEMMQLFESIHQS 193

                        170       180
                 ....*....|....*....|....*....
gi 736694016 186 -RIVIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:PRK13643 194 gQTVVLVTHLMDDVADYADyVYLLEKGHI 222
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 4-204 2.95e-13

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 69.36  E-value: 2.95e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   4 LIEIKKV---FGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFT----KKELS-- 73
Cdd:PRK10247   7 LLQLQNVgylAGDAKILNNISFSLRAGeFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKpeiyRQQVSyc 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  74 --------DYYYNSIGFIWQdyqlIEylsvecnidlvlslsnlNKAERKMKVAKVLEELGI-SGLAKMKVAKLSGGQKQR 144
Cdd:PRK10247  87 aqtptlfgDTVYDNLIFPWQ----IR-----------------NQQPDPAIFLDDLERFALpDTILTKNIAELSGGEKQR 145

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 145 VAIARALVKDPEIIIADEPTKALD---LLAANKIMTEL---KKIAkeriVIIVTHDKGLIEKDANV 204
Cdd:PRK10247 146 ISLIRNLQFMPKVLLLDEITSALDesnKHNVNEIIHRYvreQNIA----VLWVTHDKDEINHADKV 207
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 1-167 3.13e-13

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 72.65  E-value: 3.13e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGM--DQNFEGDVYFNNQSMKrftKKELSDYYY 77
Cdd:PRK13549   5 LLEMKNITKTFGGVKALDNVSLKVRAGeIVSLCGENGAGKSTLMKVLSGVypHGTYEGEIIFEGEELQ---ASNIRDTER 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  78 NSIGFIWQDYQLIEYLSVECNIDLVLSLSN---LNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKD 154
Cdd:PRK13549  82 AGIAIIHQELALVKELSVLENIFLGNEITPggiMDYDAMYLRAQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNKQ 161

                        170
                 ....*....|...
gi 736694016 155 PEIIIADEPTKAL 167
Cdd:PRK13549 162 ARLLILDEPTASL 174
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 107-169 3.24e-13

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 71.15  E-value: 3.24e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 107 NLNKAERKMKVAKVLEELGIsglaKMKVAK-----LSGGQKQRVAIARALVKDPEIIIADEPTKALDL 169
Cdd:PRK11308 124 SLSAAERREKALAMMAKVGL----RPEHYDryphmFSGGQRQRIAIARALMLDPDVVVADEPVSALDV 187
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 24-217 3.43e-13

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 70.07  E-value: 3.43e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  24 FQKGLNFIYGPSGSGKTTLLNIISGMDQ-----NFEGDVYFNNQSM--KRFT----KKELSDYYYNSIGFIWQDYQLIEY 92
Cdd:PRK14258  31 YQSKVTAIIGPSGCGKSTFLKCLNRMNElesevRVEGRVEFFNQNIyeRRVNlnrlRRQVSMVHPKPNLFPMSVYDNVAY 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  93 lsvecNIDLV-----LSLSNLnkAERKMKVAKVLEELgisglaKMKVAK----LSGGQKQRVAIARALVKDPEIIIADEP 163
Cdd:PRK14258 111 -----GVKIVgwrpkLEIDDI--VESALKDADLWDEI------KHKIHKsaldLSGGQQQRLCIARALAVKPKVLLMDEP 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 164 TKALDLLAANKI--MTELKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVGQ 217
Cdd:PRK14258 178 CFGLDPIASMKVesLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGNENRIGQ 233
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 16-216 3.97e-13

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 69.10  E-value: 3.97e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  16 VLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQ--SMKRFTkkelsdyyynsIGFiwqDYQLiey 92
Cdd:cd03220   37 ALKDVSFEVPRGERIgLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRvsSLLGLG-----------GGF---NPEL--- 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  93 lSVECNIDLVLSLSNLNKAERKMKVAKVLE--ELGISGLAKMKvaKLSGGQKQRVAIARALVKDPEIIIADEPTKALDL- 169
Cdd:cd03220  100 -TGRENIYLNGRLLGLSRKEIDEKIDEIIEfsELGDFIDLPVK--TYSSGMKARLAFAIATALEPDILLIDEVLAVGDAa 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 736694016 170 --LAANKIMTELKKiaKERIVIIVTHDKGLIEK--DANVYsMEQGQLKLVG 216
Cdd:cd03220  177 fqEKCQRRLRELLK--QGKTVILVSHDPSSIKRlcDRALV-LEKGKIRFDG 224
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
31-191 4.39e-13

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 71.97  E-value: 4.39e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDyyyNSIGFIWQDYQ---LIEYLSVECNIdlvlSLSN 107
Cdd:COG1129  283 IAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRDAIR---AGIAYVPEDRKgegLVLDLSIRENI----TLAS 355

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 108 LNK----------AERKMkVAKVLEELGI-SGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIM 176
Cdd:COG1129  356 LDRlsrgglldrrRERAL-AEEYIKRLRIkTPSPEQPVGNLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIY 434

                        170
                 ....*....|....*
gi 736694016 177 TELKKIAKERIVIIV 191
Cdd:COG1129  435 RLIRELAAEGKAVIV 449
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 5-218 4.71e-13

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 72.14  E-value: 4.71e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    5 IEIKKV---FGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQ--NFEGDVYFNnqsMKRFTKKElsdyYYN 78
Cdd:TIGR03269   1 IEVKNLtkkFDGKEVLKNISFTIEEGEVLgILGRSGAGKSVLMHVLRGMDQyePTSGRIIYH---VALCEKCG----YVE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   79 SIGFIWQDYQLIEYLSVECNIDLVlslsNLNKAERK--MK---------------------VAKVLEELGISGLAKMKVA 135
Cdd:TIGR03269  74 RPSKVGEPCPVCGGTLEPEEVDFW----NLSDKLRRriRKriaimlqrtfalygddtvldnVLEALEEIGYEGKEAVGRA 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  136 ------------------KLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHDK 195
Cdd:TIGR03269 150 vdliemvqlshrithiarDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASgiSMVLTSHWP 229

                         250       260
                  ....*....|....*....|....*
gi 736694016  196 GLIEK--DANVYsMEQGQLKLVGQS 218
Cdd:TIGR03269 230 EVIEDlsDKAIW-LENGEIKEEGTP 253
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 31-220 5.47e-13

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 72.08  E-value: 5.47e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyynsigfiwqdyQLIEYLSVECNIDLVLSLSNL-N 109
Cdd:TIGR01193 505 IVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTLR--------------QFINYLPQEPYIFSGSILENLlL 570

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  110 KAERKMKVAKVLEELGIS----GLAKMKV----------AKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKI 175
Cdd:TIGR01193 571 GAKENVSQDEIWAACEIAeikdDIENMPLgyqtelseegSSISGGQKQRIALARALLTDSKVLILDESTSNLDTITEKKI 650

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 736694016  176 MTELKKIaKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVGQSKQ 220
Cdd:TIGR01193 651 VNNLLNL-QDKTIIFVAHRLSVAKQSDKIIVLDHGKIIEQGSHDE 694
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 28-193 5.54e-13

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 68.51  E-value: 5.54e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  28 LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQDYQLIEyLSVECNIDLVlslSN 107
Cdd:cd03290   29 LTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRYSVAYAAQKPWLLN-ATVEENITFG---SP 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 108 LNKAERKMKV-AKVLE------------ELGISGLakmkvaKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANK 174
Cdd:cd03290  105 FNKQRYKAVTdACSLQpdidllpfgdqtEIGERGI------NLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDH 178

                        170       180
                 ....*....|....*....|..
gi 736694016 175 IMTE--LKKIAKE-RIVIIVTH 193
Cdd:cd03290  179 LMQEgiLKFLQDDkRTLVLVTH 200
cbiO PRK13642
energy-coupling factor transporter ATPase;
31-212 7.83e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 69.35  E-value: 7.83e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQsmkRFTKKELSDYYyNSIGFIWQ--DYQLIEyLSVECNIDLVLSLSNL 108
Cdd:PRK13642  38 IIGQNGSGKSTTARLIDGLFEEFEGKVKIDGE---LLTAENVWNLR-RKIGMVFQnpDNQFVG-ATVEDDVAFGMENQGI 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 109 NKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER-- 186
Cdd:PRK13642 113 PREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYql 192

                        170       180
                 ....*....|....*....|....*.
gi 736694016 187 IVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:PRK13642 193 TVLSITHDLDEAASSDRILVMKAGEI 218
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
13-233 8.27e-13

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 71.20  E-value: 8.27e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  13 NEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQL-- 89
Cdd:PRK11176 355 EVPALRNINFKIPAGKTVaLVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTLASLR----NQVALVSQNVHLfn 430

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  90 ------IEYLSVEcnidlVLSLSNLNKAER---------KMK--VAKVLEELGISglakmkvakLSGGQKQRVAIARALV 152
Cdd:PRK11176 431 dtiannIAYARTE-----QYSREQIEEAARmayamdfinKMDngLDTVIGENGVL---------LSGGQRQRIAIARALL 496

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 153 KDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVGQSKQHSKDDGKNNRLN 232
Cdd:PRK11176 497 RDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEILVVEDGEIVERGTHAELLAQNGVYAQLH 576


                 .
gi 736694016 233 K 233
Cdd:PRK11176 577 K 577
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
33-196 1.60e-12

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 68.37  E-value: 1.60e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGFIWQDYQLIEylsvecniDLVL-------SL 105
Cdd:PRK15056  40 GVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKNLVAYVPQSEEVDWSFPVLVE--------DVVMmgryghmGW 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 106 SNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE 185
Cdd:PRK15056 112 LRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDE 191

                        170
                 ....*....|..
gi 736694016 186 -RIVIIVTHDKG 196
Cdd:PRK15056 192 gKTMLVSTHNLG 203
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 118-212 1.72e-12

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 67.80  E-value: 1.72e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 118 AKVLEELGISG---LAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERI--VIIVT 192
Cdd:PRK10418 119 TAALEAVGLENaarVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLDVVAQARILDLLESIVQKRAlgMLLVT 198

                         90       100
                 ....*....|....*....|.
gi 736694016 193 HDKGLIEKDAN-VYSMEQGQL 212
Cdd:PRK10418 199 HDMGVVARLADdVAVMSHGRI 219
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 1-198 1.77e-12

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 67.83  E-value: 1.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKV---FGNEIVLNHLSGDFQKG--LNFIyGPSGSGKTTLLNIISGMDQNFEGDvyfnnqsmkrftkkelsdy 75
Cdd:PRK09544   1 MTSLVSLENVsvsFGQRRVLSDVSLELKPGkiLTLL-GPNGAGKSTLVRVVLGLVAPDEGV------------------- 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  76 yynsigfIWQDYQL-IEYLSVECNIDLVLSLS-----NLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIAR 149
Cdd:PRK09544  61 -------IKRNGKLrIGYVPQKLYLDTTLPLTvnrflRLRPGTKKEDILPALKRVQAGHLIDAPMQKLSGGETQRVLLAR 133

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 150 ALVKDPEIIIADEPTKALDL---LA----ANKIMTELkkiakERIVIIVTHDKGLI 198
Cdd:PRK09544 134 ALLNRPQLLVLDEPTQGVDVngqVAlydlIDQLRREL-----DCAVLMVSHDLHLV 184
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 4-170 1.81e-12

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 70.04  E-value: 1.81e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   4 LIEIKKV---FGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGmD--QNFEGDVYFnnqsmkrFTKKElsdyyy 77
Cdd:PRK10938 260 RIVLNNGvvsYNDRPILHNLSWQVNPGEHWqIVGPNGAGKSTLLSLITG-DhpQGYSNDLTL-------FGRRR------ 325

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  78 NSIGFIWQDYQLIEYLSVECNIDLVLSLSNLN---------------KAERKMKVAKV-LEELGISG-LAKMKVAKLSGG 140
Cdd:PRK10938 326 GSGETIWDIKKHIGYVSSSLHLDYRVSTSVRNvilsgffdsigiyqaVSDRQQKLAQQwLDILGIDKrTADAPFHSLSWG 405

                        170       180       190
                 ....*....|....*....|....*....|
gi 736694016 141 QKQRVAIARALVKDPEIIIADEPTKALDLL 170
Cdd:PRK10938 406 QQRLALIVRALVKHPTLLILDEPLQGLDPL 435
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 1-167 2.49e-12

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 69.47  E-value: 2.49e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGM--DQNFEGDVYFNNQSMKrftKKELSDYYY 77
Cdd:TIGR02633   1 LLEMKGIVKTFGGVKALDGIDLEVRPGeCVGLCGENGAGKSTLMKILSGVypHGTWDGEIYWSGSPLK---ASNIRDTER 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   78 NSIGFIWQDYQLIEYLSVECNI----DLVLSLSNLNKAERKMKVAKVLEELGISGL-AKMKVAKLSGGQKQRVAIARALV 152
Cdd:TIGR02633  78 AGIVIIHQELTLVPELSVAENIflgnEITLPGGRMAYNAMYLRAKNLLRELQLDADnVTRPVGDYGGGQQQLVEIAKALN 157

                         170
                  ....*....|....*
gi 736694016  153 KDPEIIIADEPTKAL 167
Cdd:TIGR02633 158 KQARLLILDEPSSSL 172
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 33-194 2.50e-12

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 68.58  E-value: 2.50e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYyNSIGFIWQDyqLIEYLSVECNID------LVLSLS 106
Cdd:PRK15079  54 GESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWRAVR-SDIQMIFQD--PLASLNPRMTIGeiiaepLRTYHP 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 107 NLNKAERKMKVAKVLEELGI-SGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKE 185
Cdd:PRK15079 131 KLSRQEVKDRVKAMMLKVGLlPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQRE 210

                        170
                 ....*....|.
gi 736694016 186 R--IVIIVTHD 194
Cdd:PRK15079 211 MglSLIFIAHD 221
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 33-216 2.84e-12

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 69.88  E-value: 2.84e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYYYNsIGFIWQD------------YQLIEYLSVECNID 100
Cdd:PRK10261 357 GESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRD-IQFIFQDpyasldprqtvgDSIMEPLRVHGLLP 435

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 101 lvlslsnlNKAERKmKVAKVLEELGISGLAKMKVA-KLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTEL 179
Cdd:PRK10261 436 --------GKAAAA-RVAWLLERVGLLPEHAWRYPhEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLL 506

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 736694016 180 KKIAKERIV--IIVTHDKGLIEKDAN-VYSMEQGQLKLVG 216
Cdd:PRK10261 507 LDLQRDFGIayLFISHDMAVVERISHrVAVMYLGQIVEIG 546
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 26-193 3.06e-12

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 66.36  E-value: 3.06e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  26 KGLNF---------IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQLIEYlSVE 96
Cdd:cd03244   21 KNISFsikpgekvgIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDLR----SRISIIPQDPVLFSG-TIR 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  97 CNIDLVLSLSN--LNKAERKMKVAKVLEELGISGLAKMKV--AKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAA 172
Cdd:cd03244   96 SNLDPFGEYSDeeLWQALERVGLKEFVESLPGGLDTVVEEggENLSVGQRQLLCLARALLRKSKILVLDEATASVDPETD 175

                        170       180
                 ....*....|....*....|.
gi 736694016 173 NKIMTELKKIAKERIVIIVTH 193
Cdd:cd03244  176 ALIQKTIREAFKDCTVLTIAH 196
cbiO PRK13641
energy-coupling factor transporter ATPase;
31-212 4.12e-12

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 67.16  E-value: 4.12e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYF---------NNQSMKRFTKKElsdyyynSIGFIWQDYQLIEYLSVEcniDL 101
Cdd:PRK13641  38 LVGHTGSGKSTLMQHFNALLKPSSGTITIagyhitpetGNKNLKKLRKKV-------SLVFQFPEAQLFENTVLK---DV 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 102 VLSLSNLNKAERKMKVA--KVLEELGIS-GLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTE 178
Cdd:PRK13641 108 EFGPKNFGFSEDEAKEKalKWLKKVGLSeDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRKEMMQL 187

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 736694016 179 LKKIAKE-RIVIIVTHDKGLIEKDAN-VYSMEQGQL 212
Cdd:PRK13641 188 FKDYQKAgHTVILVTHNMDDVAEYADdVLVLEHGKL 223
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 31-202 4.38e-12

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 69.21  E-value: 4.38e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISG---MDQ---NFEGDVYFN--NQSMKRftKKELSDYYYNSIGFIWQDYQLIEYLSVECNIDLV 102
Cdd:PRK11147  34 LVGRNGAGKSTLMKILNGevlLDDgriIYEQDLIVArlQQDPPR--NVEGTVYDFVAEGIEEQAEYLKRYHDISHLVETD 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 103 LSLSNLNKAERKM-------------KVAKVLEELGISglAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDL 169
Cdd:PRK11147 112 PSEKNLNELAKLQeqldhhnlwqlenRINEVLAQLGLD--PDAALSSLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDI 189

                        170       180       190
                 ....*....|....*....|....*....|...
gi 736694016 170 LAANKIMTELKKIaKERIVIIvTHDKGLIEKDA 202
Cdd:PRK11147 190 ETIEWLEGFLKTF-QGSIIFI-SHDRSFIRNMA 220
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 17-192 5.96e-12

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 64.96  E-value: 5.96e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  17 LNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISG--MDQNFEGDVYFNNqsmkrftkKELSDYYYNSIGFIWQDYQLIEYL 93
Cdd:cd03232   23 LNNISGYVKPGtLTALMGESGAGKTTLLDVLAGrkTAGVITGEILING--------RPLDKNFQRSTGYVEQQDVHSPNL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  94 SVEcnidlvlslsnlnkaerkmkvakvlEELGISGLAKmkvaKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAAN 173
Cdd:cd03232   95 TVR-------------------------EALRFSALLR----GLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAY 145

                        170
                 ....*....|....*....
gi 736694016 174 KIMTELKKIAKERIVIIVT 192
Cdd:cd03232  146 NIVRFLKKLADSGQAILCT 164
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 14-199 6.09e-12

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 68.68  E-value: 6.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  14 EIVLNHLSGDFQKG---LnfIYGPSGSGKTTLLNIISGMDQNFEGDVYF--NNQSMkrftkkelsdyyynsigFIWQD-Y 87
Cdd:COG4178  376 RPLLEDLSLSLKPGerlL--ITGPSGSGKSTLLRAIAGLWPYGSGRIARpaGARVL-----------------FLPQRpY 436

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  88 -------QLIEYLSVECNIDLvlslsnlnkAErkmkVAKVLEELGISGLAKM--------KVakLSGGQKQRVAIARALV 152
Cdd:COG4178  437 lplgtlrEALLYPATAEAFSD---------AE----LREALEAVGLGHLAERldeeadwdQV--LSLGEQQRLAFARLLL 501

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 736694016 153 KDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIVTHDKGLIE 199
Cdd:COG4178  502 HKPDWLFLDEATSALDEENEAALYQLLREELPGTTVISVGHRSTLAA 548
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 8-195 6.88e-12

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 68.42  E-value: 6.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    8 KKVFGNEIVLNHLSgdfqkgLNFIY-------GPSGSGKTTLLNIISGMDQNFEGDVYFNnQSMKrftkkelsdyyynsI 80
Cdd:TIGR03719  12 KVVPPKKEILKDIS------LSFFPgakigvlGLNGAGKSTLLRIMAGVDKDFNGEARPQ-PGIK--------------V 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   81 GFIWQDYQLIEYLSVECNI-----DLVLSLSNLNK-----AERKMKVAKVLEELG-------------------ISGLA- 130
Cdd:TIGR03719  71 GYLPQEPQLDPTKTVRENVeegvaEIKDALDRFNEisakyAEPDADFDKLAAEQAelqeiidaadawdldsqleIAMDAl 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  131 -----KMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKerIVIIVTHDK 195
Cdd:TIGR03719 151 rcppwDADVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHLQEYPG--TVVAVTHDR 218
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 7-192 9.88e-12

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 64.59  E-value: 9.88e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   7 IKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNF---EGDVYFNNQSMKRFTKKELSDYYYNSigf 82
Cdd:cd03233   13 TGKGRSKIPILKDFSGVVKPGeMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAEKYPGEIIYVS--- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  83 iwQDYQLIEYLSVECNIDLVLSLSNlNKAERkmkvakvleelgisglakmkvaKLSGGQKQRVAIARALVKDPEIIIADE 162
Cdd:cd03233   90 --EEDVHFPTLTVRETLDFALRCKG-NEFVR----------------------GISGGERKRVSIAEALVSRASVLCWDN 144

                        170       180       190
                 ....*....|....*....|....*....|.
gi 736694016 163 PTKALDLLAANKIMTELKKIAKE-RIVIIVT 192
Cdd:cd03233  145 STRGLDSSTALEILKCIRTMADVlKTTTFVS 175
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 16-216 1.22e-11

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 65.10  E-value: 1.22e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  16 VLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNnqsmkrftkkelsdyyyNSIGFiwqdyqLIEY-- 92
Cdd:COG1134   41 ALKDVSFEVERGESVgIIGRNGAGKSTLLKLIAGILEPTSGRVEVN-----------------GRVSA------LLELga 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  93 -----LSVECNIDLVLSLSNLNKAERKMKVAKVLE--ELG--IsglaKMKVAKLSGGQKQRVAIARALVKDPEIIIADEp 163
Cdd:COG1134   98 gfhpeLTGRENIYLNGRLLGLSRKEIDEKFDEIVEfaELGdfI----DQPVKTYSSGMRARLAFAVATAVDPDILLVDE- 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 736694016 164 tkaldLLAA------NKIMTELKKIAKE-RIVIIVTHDKGLIEK--DANVYsMEQGQLKLVG 216
Cdd:COG1134  173 -----VLAVgdaafqKKCLARIRELRESgRTVIFVSHSMGAVRRlcDRAIW-LEKGRLVMDG 228
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 31-194 1.43e-11

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 65.08  E-value: 1.43e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISG-MDQNFegDVYFNNQS----MKRFTKKELSDYYYNSIGFIWQDYQLIEYL-----SVECNId 100
Cdd:cd03236   31 LVGPNGIGKSTALKILAGkLKPNL--GKFDDPPDwdeiLDEFRGSELQNYFTKLLEGDVKVIVKPQYVdlipkAVKGKV- 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 101 lvlsLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDL---LAANKIMT 177
Cdd:cd03236  108 ----GELLKKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIkqrLNAARLIR 183

                        170
                 ....*....|....*..
gi 736694016 178 ELkkIAKERIVIIVTHD 194
Cdd:cd03236  184 EL--AEDDNYVLVVEHD 198
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 19-220 2.35e-11

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 66.80  E-value: 2.35e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  19 HLSGDFQKGLNF-IYGPSGSGKT-TLLNIISGMDQNfEGDVYFNNQSMKR----------FTKKELSDYYYNSIGFIWQD 86
Cdd:PRK10261  34 NLSFSLQRGETLaIVGESGSGKSvTALALMRLLEQA-GGLVQCDKMLLRRrsrqvielseQSAAQMRHVRGADMAMIFQE 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  87 --YQLIEYLSVECNIDLVLSL-SNLNKAERKMKVAKVLEELGISGlAKMKVAK----LSGGQKQRVAIARALVKDPEIII 159
Cdd:PRK10261 113 pmTSLNPVFTVGEQIAESIRLhQGASREEAMVEAKRMLDQVRIPE-AQTILSRyphqLSGGMRQRVMIAMALSCRPAVLI 191

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAKERI--VIIVTHDKGLIEKDAN-VYSMEQGQLKLVGQSKQ 220
Cdd:PRK10261 192 ADEPTTALDVTIQAQILQLIKVLQKEMSmgVIFITHDMGVVAEIADrVLVMYQGEAVETGSVEQ 255
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
33-194 2.59e-11

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 64.42  E-value: 2.59e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQLIEYLSVEcniDLVL--------S 104
Cdd:PRK10575  44 GHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFA----RKVAYLPQQLPAAEGMTVR---ELVAigrypwhgA 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 105 LSNLNKAERKmKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAK 184
Cdd:PRK10575 117 LGRFGAADRE-KVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQ 195

                        170
                 ....*....|..
gi 736694016 185 ER--IVIIVTHD 194
Cdd:PRK10575 196 ERglTVIAVLHD 207
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 33-247 3.85e-11

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 66.58  E-value: 3.85e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTkkelsDYYYNSIGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAE 112
Cdd:TIGR01257  963 GHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNL-----DAVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGRSWEE 1037

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   113 RKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIVT 192
Cdd:TIGR01257 1038 AQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMST 1117

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 736694016   193 H--DKGLIEKDaNVYSMEQGQLKLVGQSkqhskddgknnrlnkppyLSLKNCISQSF 247
Cdd:TIGR01257 1118 HhmDEADLLGD-RIAIISQGRLYCSGTP------------------LFLKNCFGTGF 1155
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 31-211 3.89e-11

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 63.22  E-value: 3.89e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGmdqNF---EGDVYFNNQS----MKRFTKKELSDYYYNSIGFIWQdyqlieYLSV---ECNID 100
Cdd:COG4778   42 LTGPSGAGKSTLLKCIYG---NYlpdSGSILVRHDGgwvdLAQASPREILALRRRTIGYVSQ------FLRViprVSALD 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 101 LV---LSLSNLNKAERKMKVAKVLEELGI-SGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDllAANK-I 175
Cdd:COG4778  113 VVaepLLERGVDREEARARARELLARLNLpERLWDLPPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLD--AANRaV 190

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 736694016 176 MTELKKIAKERIVIIVT--HDKGLIEKDAN-VYSMEQGQ 211
Cdd:COG4778  191 VVELIEEAKARGTAIIGifHDEEVREAVADrVVDVTPFS 229
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 28-168 4.15e-11

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 65.91  E-value: 4.15e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  28 LNFIY-------GPSGSGKTTLLNIISGMDQNFEGDVYfnnqsmkrftkkeLSDYYynSIGFIWQDYQLIEYLSVECNI- 99
Cdd:PRK11819  28 LSFFPgakigvlGLNGAGKSTLLRIMAGVDKEFEGEAR-------------PAPGI--KVGYLPQEPQLDPEKTVRENVe 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 100 ----DLVLSLSNLNK-----AERKMKVAKVLEELG-----ISGL--------------------AKMKVAKLSGGQKQRV 145
Cdd:PRK11819  93 egvaEVKAALDRFNEiyaayAEPDADFDALAAEQGelqeiIDAAdawdldsqleiamdalrcppWDAKVTKLSGGERRRV 172

                        170       180
                 ....*....|....*....|...
gi 736694016 146 AIARALVKDPEIIIADEPTKALD 168
Cdd:PRK11819 173 ALCRLLLEKPDMLLLDEPTNHLD 195
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 30-200 5.39e-11

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 64.34  E-value: 5.39e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  30 FIyGPSGSGKTTLLNIISGMDQNFEGDVYFNN----QSMKRFTKKelsdyyynsIGFIW-QDYQLIEYLSVECNIDLVLS 104
Cdd:COG4586   53 FI-GPNGAGKSTTIKMLTGILVPTSGEVRVLGyvpfKRRKEFARR---------IGVVFgQRSQLWWDLPAIDSFRLLKA 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 105 LSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAK 184
Cdd:COG4586  123 IYRIPDAEYKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNR 202

                        170
                 ....*....|....*...
gi 736694016 185 ER--IVIIVTHDKGLIEK 200
Cdd:COG4586  203 ERgtTILLTSHDMDDIEA 220
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 11-210 7.28e-11

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 63.09  E-value: 7.28e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  11 FGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRftkkeLSDYYYNSIGFI--WQDY 87
Cdd:PRK11300  15 FGGLLAVNNVNLEVREQEIVsLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEG-----LPGHQIARMGVVrtFQHV 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  88 QLIEYLSVECNIdLVLSLSNLN--------------KAERKM--KVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARAL 151
Cdd:PRK11300  90 RLFREMTVIENL-LVAQHQQLKtglfsgllktpafrRAESEAldRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCM 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 152 VKDPEIIIADEPTKALDllaaNKIMTELKK-IAKER-----IVIIVTHDKGLIEKDAN-VYSMEQG 210
Cdd:PRK11300 169 VTQPEILMLDEPAAGLN----PKETKELDElIAELRnehnvTVLLIEHDMKLVMGISDrIYVVNQG 230
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 1-194 9.89e-11

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 64.09  E-value: 9.89e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNS 79
Cdd:PRK09536   3 MIDVSDLSVEFGDTTVLDGVDLSVREGsLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAAS----RR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNIDL-----VLSLSNLNKAERKMkVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKD 154
Cdd:PRK09536  79 VASVPQDTSLSFEFDVRQVVEMgrtphRSRFDTWTETDRAA-VERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQA 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 736694016 155 PEIIIADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTHD 194
Cdd:PRK09536 158 TPVLLLDEPTASLDINHQVRTLELVRRLVDDgKTAVAAIHD 198
cbiO PRK13644
energy-coupling factor transporter ATPase;
31-217 1.00e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 63.08  E-value: 1.00e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTK-KELSDYyynsIGFIWQDYQlIEYLSVECNIDLVLSLSNL- 108
Cdd:PRK13644  33 IIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKlQGIRKL----VGIVFQNPE-TQFVGRTVEEDLAFGPENLc 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 109 -NKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKI-AKER 186
Cdd:PRK13644 108 lPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAVLERIKKLhEKGK 187

                        170       180       190
                 ....*....|....*....|....*....|.
gi 736694016 187 IVIIVTHDKGLIEKDANVYSMEQGQLKLVGQ 217
Cdd:PRK13644 188 TIVYITHNLEELHDADRIIVMDRGKIVLEGE 218
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 1-225 1.02e-10

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 64.69  E-value: 1.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYyynS 79
Cdd:PRK15439  11 LLCARSISKQYSGVEVLKGIDFTLHAGeVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPAKAHQL---G 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNIdlVLSLSNLNKAERKMKvaKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:PRK15439  88 IYLVPQEPLLFPNLSVKENI--LFGLPKRQASMQKMK--QLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSRILI 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAKERIVII-VTHDKGLIEKDANVYS-MEQGQLKLVGQSKQHSKDD 225
Cdd:PRK15439 164 LDEPTASLTPAETERLFSRIRELLAQGVGIVfISHKLPEIRQLADRISvMRDGTIALSGKTADLSTDD 231
cbiO PRK13645
energy-coupling factor transporter ATPase;
25-216 1.14e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 63.10  E-value: 1.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  25 QKGLNFIYGPSGSGKTTLLNIISGM-----DQNFEGDvYFNNQSMKRFtkKELSDYYyNSIGFIWQ--DYQLIEYlSVEC 97
Cdd:PRK13645  36 KNKVTCVIGTTGSGKSTMIQLTNGLiisetGQTIVGD-YAIPANLKKI--KEVKRLR-KEIGLVFQfpEYQLFQE-TIEK 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  98 NIDLVLSLSNLNKAERKMKVAKVLEELGI-SGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIM 176
Cdd:PRK13645 111 DIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFI 190

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 736694016 177 TELKKIAKE--RIVIIVTHDKGLIEKDAN-VYSMEQGQLKLVG 216
Cdd:PRK13645 191 NLFERLNKEykKRIIMVTHNMDQVLRIADeVIVMHEGKVISIG 233
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
1-214 2.17e-10

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 61.43  E-value: 2.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkrfTKKELSDYYYNS 79
Cdd:PRK11614   5 MLSFDKVSAHYGKIQALHEVSLHINQGeIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDI---TDWQTAKIMREA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNidLVLSLSNLNKAERKMKVAKVLEELgiSGLAKMKVAK---LSGGQKQRVAIARALVKDPE 156
Cdd:PRK11614  82 VAIVPEGRRVFSRMTVEEN--LAMGGFFAERDQFQERIKWVYELF--PRLHERRIQRagtMSGGEQQMLAIGRALMSQPR 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 157 IIIADEPTKALDLLAANKIMTELKKIAKERIVIIvthdkgLIEKDANV--------YSMEQGQLKL 214
Cdd:PRK11614 158 LLLLDEPSLGLAPIIIQQIFDTIEQLREQGMTIF------LVEQNANQalkladrgYVLENGHVVL 217
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 16-199 2.68e-10

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 60.74  E-value: 2.68e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  16 VLNHLSGDFQKG-LNFIYGPSGSGKTTLLniisgmdqnfegdvyfnnqsmkRFTKKELSDYYYNSIGFIWQDyQLIEYLS 94
Cdd:COG2401   45 VLRDLNLEIEPGeIVLIVGASGSGKSTLL----------------------RLLAGALKGTPVAGCVDVPDN-QFGREAS 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  95 VecnIDLVLSLSNLNKAerkmkvakvLEELGISGLA-----KMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDL 169
Cdd:COG2401  102 L---IDAIGRKGDFKDA---------VELLNAVGLSdavlwLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDR 169

                        170       180       190
                 ....*....|....*....|....*....|..
gi 736694016 170 LAANKIMTELKKIAKERIV--IIVTHDKGLIE 199
Cdd:COG2401  170 QTAKRVARNLQKLARRAGItlVVATHHYDVID 201
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 31-194 2.84e-10

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 61.48  E-value: 2.84e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSmkrftkKELSDYYYNS-----------IGFIWQDYQ--LIEYLSVEC 97
Cdd:PRK11701  37 IVGESGSGKTTLLNALSARLAPDAGEVHYRMRD------GQLRDLYALSeaerrrllrteWGFVHQHPRdgLRMQVSAGG 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  98 NIdlvlslsnlnkAERKMKVAK----VLEELGISGLAKMKVA---------KLSGGQKQRVAIARALVKDPEIIIADEPT 164
Cdd:PRK11701 111 NI-----------GERLMAVGArhygDIRATAGDWLERVEIDaariddlptTFSGGMQQRLQIARNLVTHPRLVFMDEPT 179

                        170       180       190
                 ....*....|....*....|....*....|..
gi 736694016 165 KALDLLAANKIMTELKKIAKER--IVIIVTHD 194
Cdd:PRK11701 180 GGLDVSVQARLLDLLRGLVRELglAVVIVTHD 211
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 33-232 2.87e-10

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 63.89  E-value: 2.87e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   33 GPSGSGKTTLLNIISGMDQNFEGDVYFNN-QSMKRFTKKelsdYYYNSIGFIWQD----------------YQL--IEYL 93
Cdd:PTZ00265  418 GESGCGKSTILKLIERLYDPTEGDIIINDsHNLKDINLK----WWRSKIGVVSQDpllfsnsiknnikyslYSLkdLEAL 493

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   94 SVECNIDLVLSLSNLNK-----AERKMKVAKVLEELGISGLAKMK----------------------------------- 133
Cdd:PTZ00265  494 SNYYNEDGNDSQENKNKrnscrAKCAGDLNDMSNTTDSNELIEMRknyqtikdsevvdvskkvlihdfvsalpdkyetlv 573

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  134 ---VAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLA---ANKIMTELKKiAKERIVIIVTHDKGLIEKDANVYSM 207
Cdd:PTZ00265  574 gsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSeylVQKTINNLKG-NENRITIIIAHRLSTIRYANTIFVL 652

                         250       260
                  ....*....|....*....|....*...
gi 736694016  208 ---EQGQLKLVGQSKQHSKDDGKNNRLN 232
Cdd:PTZ00265  653 snrERGSTVDVDIIGEDPTKDNKENNNK 680
PLN03073 PLN03073
ABC transporter F family; Provisional
 26-198 2.97e-10

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 63.34  E-value: 2.97e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  26 KGLNF---------IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQ-SMKRFTKKElsdyyynsigfiwqdyqlIEYLSV 95
Cdd:PLN03073 526 KNLNFgidldsriaMVGPNGIGKSTILKLISGELQPSSGTVFRSAKvRMAVFSQHH------------------VDGLDL 587

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  96 ECNIDLVLSLSNLNKAERKMKVAkvLEELGISG-LAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANK 174
Cdd:PLN03073 588 SSNPLLYMMRCFPGVPEQKLRAH--LGSFGVTGnLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDAVEA 665

                        170       180
                 ....*....|....*....|....
gi 736694016 175 IMTELkkIAKERIVIIVTHDKGLI 198
Cdd:PLN03073 666 LIQGL--VLFQGGVLMVSHDEHLI 687
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 134-212 4.28e-10

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 62.38  E-value: 4.28e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 134 VAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERI-VIIVTHDKGLIEKDAN-VYSMEQGQ 211
Cdd:PRK15439 401 ARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAAQNVaVLFISSDLEEIEQMADrVLVMHQGE 480


                 .
gi 736694016 212 L 212
Cdd:PRK15439 481 I 481
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
33-191 4.38e-10

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 62.49  E-value: 4.38e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNqsmKRFTKKELSDYYYNSIGFIWQ---DYQLIEYLSVECNIDLVLSLSN-- 107
Cdd:PRK09700 296 GLVGSGRTELMNCLFGVDKRAGGEIRLNG---KDISPRSPLDAVKKGMAYITEsrrDNGFFPNFSIAQNMAISRSLKDgg 372

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 108 -------LNKAERKMKVAKVLEELGISGLA-KMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTEL 179
Cdd:PRK09700 373 ykgamglFHEVDEQRTAENQRELLALKCHSvNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVM 452

                        170
                 ....*....|..
gi 736694016 180 KKIAKERIVIIV 191
Cdd:PRK09700 453 RQLADDGKVILM 464
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 31-213 5.15e-10

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 62.15  E-value: 5.15e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   31 IYGPSGSGKTTLLNIISGM-DQNFEGDVYFNNqsmKRFTKKELSDYYYNSIGFIWQDYQ---LIEYLSVECNIdlvlSLS 106
Cdd:TIGR02633 291 VAGLVGAGRTELVQALFGAyPGKFEGNVFING---KPVDIRNPAQAIRAGIAMVPEDRKrhgIVPILGVGKNI----TLS 363

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  107 NLNKAERKMKVAKVLEELGI-SGLAKMKV---------AKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIM 176
Cdd:TIGR02633 364 VLKSFCFKMRIDAAAELQIIgSAIQRLKVktaspflpiGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIY 443

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 736694016  177 TELKKIAKERIVIIVTHDK-----GLIEKdanVYSMEQGQLK 213
Cdd:TIGR02633 444 KLINQLAQEGVAIIVVSSElaevlGLSDR---VLVIGEGKLK 482
GguA NF040905
sugar ABC transporter ATP-binding protein;
31-181 5.64e-10

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 62.11  E-value: 5.64e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGM--DQNFEGDVYFNNQSMkRFtkKELSDYYYNSIGFIWQDYQLIEYLSVECNIdlvlSLSN- 107
Cdd:NF040905  32 LCGENGAGKSTLMKVLSGVypHGSYEGEILFDGEVC-RF--KDIRDSEALGIVIIHQELALIPYLSIAENI----FLGNe 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 108 ------LNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALD------LLaanKI 175
Cdd:NF040905 105 rakrgvIDWNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLILDEPTAALNeedsaaLL---DL 181


                 ....*.
gi 736694016 176 MTELKK 181
Cdd:NF040905 182 LLELKA 187
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 33-191 8.14e-10

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 61.67  E-value: 8.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDyyyNSIGFIWQDYQLIEYLSVECNIDL-VLSLSNLNKA 111
Cdd:PRK10982  31 GENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEALE---NGISMVHQELNLVLQRSVMDNMWLgRYPTKGMFVD 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 112 ERKM--KVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIaKERIVI 189
Cdd:PRK10982 108 QDKMyrDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKL-KERGCG 186


                 ..
gi 736694016 190 IV 191
Cdd:PRK10982 187 IV 188
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 8-194 8.89e-10

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 59.73  E-value: 8.89e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   8 KKVFGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVyfnnqsmkrftKKELSDYYYNSiGFIWQD 86
Cdd:cd03237    6 MKKTLGEFTLEVEGGSISESEVIgILGPNGIGKTTFIKMLAGVLKPDEGDI-----------EIELDTVSYKP-QYIKAD 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  87 YQLieylSVEcniDLVLSLSNlNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKA 166
Cdd:cd03237   74 YEG----TVR---DLLSSITK-DFYTHPYFKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAY 145

                        170       180       190
                 ....*....|....*....|....*....|...
gi 736694016 167 LDL---LAANKImteLKKIA--KERIVIIVTHD 194
Cdd:cd03237  146 LDVeqrLMASKV---IRRFAenNEKTAFVVEHD 175
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 20-194 1.16e-09

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 59.18  E-value: 1.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  20 LSGDFQKGLNF-IYGPSGSGKTTLLNIISGMdQNFEGDVYFNNQSMKRFTKKELSDY--YY---NSIGFI---WQdyqli 90
Cdd:PRK03695  15 LSAEVRAGEILhLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPLEAWSAAELARHraYLsqqQTPPFAmpvFQ----- 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  91 eYLSvecnidlvLSL-SNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVK-DPEI------IIADE 162
Cdd:PRK03695  89 -YLT--------LHQpDKTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLQvWPDInpagqlLLLDE 159

                        170       180       190
                 ....*....|....*....|....*....|...
gi 736694016 163 PTKALDLLAANKIMTELKKIAKERIVIIVT-HD 194
Cdd:PRK03695 160 PMNSLDVAQQAALDRLLSELCQQGIAVVMSsHD 192
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 26-194 1.48e-09

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 60.81  E-value: 1.48e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  26 KGLNF---------IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDyyyNSIGFIWQDYQ---LIEYL 93
Cdd:COG3845  275 KDVSLevrageilgIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRERRR---LGVAYIPEDRLgrgLVPDM 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  94 SVECNidLVLSLSN---------LNKAERKMKVAKVLEELGI-SGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEP 163
Cdd:COG3845  352 SVAEN--LILGRYRrppfsrggfLDRKAIRAFAEELIEEFDVrTPGPDTPARSLSGGNQQKVILARELSRDPKLLIAAQP 429

                        170       180       190
                 ....*....|....*....|....*....|..
gi 736694016 164 TKALDLLAANKIMTELKKIAKERI-VIIVTHD 194
Cdd:COG3845  430 TRGLDVGAIEFIHQRLLELRDAGAaVLLISED 461
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 31-191 3.19e-09

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 59.56  E-value: 3.19e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQN-FEGDVYFNNQSMKrftKKELSDYYYNSIGFIWQD---YQLIEYLSVECNIdlvlSLS 106
Cdd:PRK13549 293 IAGLVGAGRTELVQCLFGAYPGrWEGEIFIDGKPVK---IRNPQQAIAQGIAMVPEDrkrDGIVPVMGVGKNI----TLA 365

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 107 NLNKAERKMKVAKVLEELGI-SGLAKMKV---------AKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIM 176
Cdd:PRK13549 366 ALDRFTGGSRIDDAAELKTIlESIQRLKVktaspelaiARLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIY 445

                        170
                 ....*....|....*
gi 736694016 177 TELKKIAKERIVIIV 191
Cdd:PRK13549 446 KLINQLVQQGVAIIV 460
PLN03140 PLN03140
ABC transporter G family member; Provisional
 16-193 5.54e-09

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 59.47  E-value: 5.54e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   16 VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQN--FEGDVYFNNqsmkrFTKKElsDYYYNSIGFIWQDYqlIEY 92
Cdd:PLN03140  895 LLREVTGAFRPGvLTALMGVSGAGKTTLMDVLAGRKTGgyIEGDIRISG-----FPKKQ--ETFARISGYCEQND--IHS 965

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   93 LSVECNIDLVLSL-----SNLNKAERKMKVAKVLE--EL-----GISGLAKmkVAKLSGGQKQRVAIARALVKDPEIIIA 160
Cdd:PLN03140  966 PQVTVRESLIYSAflrlpKEVSKEEKMMFVDEVMElvELdnlkdAIVGLPG--VTGLSTEQRKRLTIAVELVANPSIIFM 1043

                         170       180       190
                  ....*....|....*....|....*....|....
gi 736694016  161 DEPTKALDLLAANKIMTELKK-IAKERIVIIVTH 193
Cdd:PLN03140 1044 DEPTSGLDARAAAIVMRTVRNtVDTGRTVVCTIH 1077
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 17-190 9.13e-09

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 58.09  E-value: 9.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  17 LNHLSGDFQKGLNF------IYGPSG---SGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDyyyNSIGFIWQDY 87
Cdd:PRK10762 260 VDNLSGPGVNDVSFtlrkgeILGVSGlmgAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLA---NGIVYISEDR 336

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  88 Q---LIEYLSVECNIDL--VLSLSN----LNKAERKMKVAKVLEELGISGLAKMK-VAKLSGGQKQRVAIARALVKDPEI 157
Cdd:PRK10762 337 KrdgLVLGMSVKENMSLtaLRYFSRaggsLKHADEQQAVSDFIRLFNIKTPSMEQaIGLLSGGNQQKVAIARGLMTRPKV 416

                        170       180       190
                 ....*....|....*....|....*....|...
gi 736694016 158 IIADEPTKALDLLAANKIMTELKKIAKERIVII 190
Cdd:PRK10762 417 LILDEPTRGVDVGAKKEIYQLINQFKAEGLSII 449
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 33-167 9.45e-09

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 58.09  E-value: 9.45e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDyyyNSIGFIWQDYQLIEYLSVECNIDL----VLSLSNL 108
Cdd:PRK10762  37 GENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPKSSQE---AGIGIIHQELNLIPQLTIAENIFLgrefVNRFGRI 113

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 736694016 109 NKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKAL 167
Cdd:PRK10762 114 DWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEPTDAL 172
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 31-197 1.58e-08

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 54.47  E-value: 1.58e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEG--------DVYFNNQS--MKRFTKKELSDYyynsigfIWQDyqlieylsvecnid 100
Cdd:cd03223   32 ITGPSGTGKSSLFRALAGLWPWGSGrigmpegeDLLFLPQRpyLPLGTLREQLIY-------PWDD-------------- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 101 lvlslsnlnkaerkmkvakvleelgisglakmkvaKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELK 180
Cdd:cd03223   91 -----------------------------------VLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQLLK 135

                        170
                 ....*....|....*..
gi 736694016 181 KiaKERIVIIVTHDKGL 197
Cdd:cd03223  136 E--LGITVISVGHRPSL 150
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 31-194 1.91e-08

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 57.49  E-value: 1.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVyfnnqsmkrFTKKELSdyY---YNSIGFiwqDYQLIEYLSVECNIDLVlslSN 107
Cdd:COG1245  371 IVGPNGIGKTTFAKILAGVLKPDEGEV---------DEDLKIS--YkpqYISPDY---DGTVEEFLRSANTDDFG---SS 433

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 108 LNKAErkmkvakVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDL---LAANKImteLKKIAK 184
Cdd:COG1245  434 YYKTE-------IIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVeqrLAVAKA---IRRFAE 503

                        170
                 ....*....|..
gi 736694016 185 ER--IVIIVTHD 194
Cdd:COG1245  504 NRgkTAMVVDHD 515
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
93-171 2.08e-08

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 57.44  E-value: 2.08e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 736694016  93 LSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLA 171
Cdd:NF033858  93 LSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLS 171
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 5-192 2.13e-08

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 57.81  E-value: 2.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016     5 IEIKKvfGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISG---MDQNFEGDVYFNNqsmkrftkKELSDYYYNSI 80
Cdd:TIGR00956  769 VKIKK--EKRVILNNVDGWVKPGtLTALMGASGAGKTTLLNVLAErvtTGVITGGDRLVNG--------RPLDSSFQRSI 838

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    81 GFIWQDYQLIEYLSVECNIDLVLSL---SNLNKAERKMKVAKVLEELGISGLAKMKVAK----LSGGQKQRVAIARALVK 153
Cdd:TIGR00956  839 GYVQQQDLHLPTSTVRESLRFSAYLrqpKSVSKSEKMEYVEEVIKLLEMESYADAVVGVpgegLNVEQRKRLTIGVELVA 918

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 736694016   154 DPEIII-ADEPTKALDLLAANKIMTELKKIAKERIVIIVT 192
Cdd:TIGR00956  919 KPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCT 958
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
31-169 2.63e-08

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 54.85  E-value: 2.63e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRftkKELSDY--YYNSIGFIWQDYQLIEYLSVECNidlvlslsnL 108
Cdd:PRK13543  42 VQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATR---GDRSRFmaYLGHLPGLKADLSTLENLHFLCG---------L 109

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 736694016 109 NKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDL 169
Cdd:PRK13543 110 HGRRAKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDL 170
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
5-193 3.14e-08

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 56.65  E-value: 3.14e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   5 IEIKKV-F---GNEIVLNHLSGDF-QKGLNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNS 79
Cdd:PRK10790 341 IDIDNVsFayrDDNLVLQNINLSVpSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLR----QG 416

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYlSVECNIDLVLSLSnlnkaerKMKVAKVLEELGISGLAKM-----------KVAKLSGGQKQRVAIA 148
Cdd:PRK10790 417 VAMVQQDPVVLAD-TFLANVTLGRDIS-------EEQVWQALETVQLAELARSlpdglytplgeQGNNLSVGQKQLLALA 488

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 736694016 149 RALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIVTH 193
Cdd:PRK10790 489 RVLVQTPQILILDEATANIDSGTEQAIQQALAAVREHTTLVVIAH 533
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 26-218 3.77e-08

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 55.03  E-value: 3.77e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  26 KGLNF---------IYGPSGSGKTTLLNIISGMD--QNFEGDVYFNNQSMKRFTKKELSdyyynSIGfIWQDYQL-IEYL 93
Cdd:CHL00131  24 KGLNLsinkgeihaIMGPNGSGKSTLSKVIAGHPayKILEGDILFKGESILDLEPEERA-----HLG-IFLAFQYpIEIP 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  94 SVEcNIDLVLSLSNLNKAERKMKVAKVLEELGI----SGLAKMKVAKL--------SGGQKQRVAIARALVKDPEIIIAD 161
Cdd:CHL00131  98 GVS-NADFLRLAYNSKRKFQGLPELDPLEFLEIinekLKLVGMDPSFLsrnvnegfSGGEKKRNEILQMALLDSELAILD 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 162 EPTKALDLLAANKIMTELKKIA-KERIVIIVTHDKGLIE--KDANVYSMEQGQLKLVGQS 218
Cdd:CHL00131 177 ETDSGLDIDALKIIAEGINKLMtSENSIILITHYQRLLDyiKPDYVHVMQNGKIIKTGDA 236
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 31-213 1.09e-07

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 52.80  E-value: 1.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQLIEYlSVECNIDLVLSLSNlnk 110
Cdd:cd03369   39 IVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLR----SSLTIIPQDPTLFSG-TIRSNLDPFDEYSD--- 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 111 aERKMKVAKVLEelgiSGLakmkvaKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVII 190
Cdd:cd03369  111 -EEIYGALRVSE----GGL------NLSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTIREEFTNSTILT 179

                        170       180
                 ....*....|....*....|...
gi 736694016 191 VTHDKGLIEKDANVYSMEQGQLK 213
Cdd:cd03369  180 IAHRLRTIIDYDKILVMDAGEVK 202
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
31-194 1.20e-07

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 54.81  E-value: 1.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  31 IYGPSGSGKTTLLNIISGMDQNFEGDVYFN------------NQSMK-----RFTKKELSDYYYNSigfiwqdyqlieyl 93
Cdd:PRK13409 370 IVGPNGIGKTTFAKLLAGVLKPDEGEVDPElkisykpqyikpDYDGTvedllRSITDDLGSSYYKS-------------- 435

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  94 svecnidlvlslsnlnkaerkmkvaKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALD----L 169
Cdd:PRK13409 436 -------------------------EIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDveqrL 490

                        170       180
                 ....*....|....*....|....*..
gi 736694016 170 LAANKImtelKKIAKER--IVIIVTHD 194
Cdd:PRK13409 491 AVAKAI----RRIAEEReaTALVVDHD 513
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 17-226 3.66e-07

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 53.80  E-value: 3.66e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    17 LNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVyfnnqSMKrftkkelsdyyyNSIGFIWQDyQLIEYLSV 95
Cdd:TIGR00957  654 LNGITFSIPEGaLVAVVGQVGCGKSSLLSALLAEMDKVEGHV-----HMK------------GSVAYVPQQ-AWIQNDSL 715

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    96 ECNIDLVLSLsNLNKAERKMKVAKVLEELGI--SGLAKM---KVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLL 170
Cdd:TIGR00957  716 RENILFGKAL-NEKYYQQVLEACALLPDLEIlpSGDRTEigeKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAH 794

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 736694016   171 AANKIMTEL---KKIAKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVGQSKQHSKDDG 226
Cdd:TIGR00957  795 VGKHIFEHVigpEGVLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLQRDG 853
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
91-192 6.02e-07

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 52.04  E-value: 6.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  91 EYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLL 170
Cdd:NF000106  99 ESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPR 178

                         90       100
                 ....*....|....*....|..
gi 736694016 171 AANKIMTELKKIAKERIVIIVT 192
Cdd:NF000106 179 TRNEVWDEVRSMVRDGATVLLT 200
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 137-193 8.13e-07

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 52.72  E-value: 8.13e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  137 LSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAAN---KIMTELKKIAkERIVIIVTH 193
Cdd:PTZ00265 1359 LSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKlieKTIVDIKDKA-DKTIITIAH 1417
hmuV PRK13547
heme ABC transporter ATP-binding protein;
121-207 8.18e-07

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 50.98  E-value: 8.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 121 LEELGISGLAKMKVAKLSGGQKQRVAIARALVK---------DPEIIIADEPTKALDLLAANKIMTELKKIAKE-RI-VI 189
Cdd:PRK13547 130 LALAGATALVGRDVTTLSGGELARVQFARVLAQlwpphdaaqPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDwNLgVL 209

                         90
                 ....*....|....*...
gi 736694016 190 IVTHDKGLIEKDANVYSM 207
Cdd:PRK13547 210 AIVHDPNLAARHADRIAM 227
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 1-193 1.26e-06

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 51.94  E-value: 1.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016     1 MLSLIEIKKVFG--NEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKrftkKELSDYYY 77
Cdd:TIGR01257 1937 ILRLNELTKVYSgtSSPAVDRLCVGVRPGECFgLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSIL----TNISDVHQ 2012

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    78 NsIGFIWQDYQLIEYLSVECNIDLVLSLSNLnKAERKMKVAK-VLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPE 156
Cdd:TIGR01257 2013 N-MGYCPQFDAIDDLLTGREHLYLYARLRGV-PAEEIEKVANwSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPP 2090

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 736694016   157 IIIADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTH 193
Cdd:TIGR01257 2091 LVLLDEPTTGMDPQARRMLWNTIVSIIREgRAVVLTSH 2128
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 23-205 1.61e-06

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 49.14  E-value: 1.61e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  23 DFQKGLNFIYGPSGSGKTTLLNIIS-----GMDQNFEGDVYFNNQSMKRFTKKELSDYYYNSIGfiwQDYQLIEYLSVEC 97
Cdd:cd03240   19 EFFSPLTLIVGQNGAGKTTIIEALKyaltgELPPNSKGGAHDPKLIREGEVRAQVKLAFENANG---KKYTITRSLAILE 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  98 NIDLVlslsnlnkaeRKMKVAKVLEELgisglakmkVAKLSGGQKQ------RVAIARALVKDPEIIIADEPTKALD--- 168
Cdd:cd03240   96 NVIFC----------HQGESNWPLLDM---------RGRCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDeen 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 736694016 169 ----LLaanKIMTELKKIaKERIVIIVTHDKGLIEKDANVY 205
Cdd:cd03240  157 ieesLA---EIIEERKSQ-KNFQLIVITHDEELVDAADHIY 193
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 30-212 3.10e-06

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 47.37  E-value: 3.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    30 FIYGPSGSGKTTLLNIISGMdqnfegdvyfnnqsmkrftkkelsdYYYNSIGFIwqdyqlieylsvecnidlVLSLSNLN 109
Cdd:smart00382   6 LIVGPPGSGKTTLARALARE-------------------------LGPPGGGVI------------------YIDGEDIL 42

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   110 KAERKMKVAKVLEELGISGlakmkvaklSGGQKQRVAIARALVKDPEIIIADEPTKALD------LLAANKIMTELKKIA 183
Cdd:smart00382  43 EEVLDQLLLIIVGGKKASG---------SGELRLRLALALARKLKPDVLILDEITSLLDaeqealLLLLEELRLLLLLKS 113

                          170       180
                   ....*....|....*....|....*....
gi 736694016   184 KERIVIIVTHDKGLIEKDANVYSMEQGQL 212
Cdd:smart00382 114 EKNLTVILTTNDEKDLGPALLRRRFDRRI 142
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 9-199 3.23e-06

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 48.29  E-value: 3.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   9 KVFGNEIvLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGmDQNFE---GDVYFNNQSMkrfTKKELSDYYYNSIGFIW 84
Cdd:cd03217    9 SVGGKEI-LKGVNLTIKKGeVHALMGPNGSGKSTLAKTIMG-HPKYEvteGEILFKGEDI---TDLPPEERARLGIFLAF 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  85 QDYQLIEYLSvecNIDLvlsLSNLNKaerkmkvakvleelgisglakmkvaKLSGGQKQRVAIARALVKDPEIIIADEPT 164
Cdd:cd03217   84 QYPPEIPGVK---NADF---LRYVNE-------------------------GFSGGEKKRNEILQLLLLEPDLAILDEPD 132

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 736694016 165 KALDLLAANKIMTELKKIAKE-RIVIIVTHDKGLIE 199
Cdd:cd03217  133 SGLDIDALRLVAEVINKLREEgKSVLIITHYQRLLD 168
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
80-193 3.41e-06

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 50.51  E-value: 3.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQDYQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIII 159
Cdd:NF033858 341 VGYMSQAFSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLI 420

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 736694016 160 ADEPTKALDLLAAN---KIMTELKKiaKERIVI-IVTH 193
Cdd:NF033858 421 LDEPTSGVDPVARDmfwRLLIELSR--EDGVTIfISTH 456
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 16-185 3.55e-06

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 50.49  E-value: 3.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    16 VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNF----EGDVYFNNQSMKRFTKKELSDYYYNSigfiwQDYQLI 90
Cdd:TIGR00956   76 ILKPMDGLIKPGeLTVVLGRPGSGCSTLLKTIASNTDGFhigvEGVITYDGITPEEIKKHYRGDVVYNA-----ETDVHF 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    91 EYLSVECNIDLVLSLS-------NLNKAERKMKVAKV-LEELGISGLAKMKVAK-----LSGGQKQRVAIARALVKDPEI 157
Cdd:TIGR00956  151 PHLTVGETLDFAARCKtpqnrpdGVSREEYAKHIADVyMATYGLSHTRNTKVGNdfvrgVSGGERKRVSIAEASLGGAKI 230

                          170       180
                   ....*....|....*....|....*...
gi 736694016   158 IIADEPTKALDLLAANKIMTELKKIAKE 185
Cdd:TIGR00956  231 QCWDNATRGLDSATALEFIRALKTSANI 258
PLN03073 PLN03073
ABC transporter F family; Provisional
 125-193 4.42e-06

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 49.86  E-value: 4.42e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 736694016 125 GISGLAKMKVAK---LSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKerIVIIVTH 193
Cdd:PLN03073 330 GLSFTPEMQVKAtktFSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYLLKWPK--TFIVVSH 399
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 125-194 6.50e-06

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 47.18  E-value: 6.50e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 736694016 125 GISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDL---LAANKIMTELKKIAKeRIVIIVTHD 194
Cdd:cd03222   60 GITPVYKPQYIDLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIeqrLNAARAIRRLSEEGK-KTALVVEHD 131
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 131-189 7.20e-06

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 48.96  E-value: 7.20e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 736694016 131 KMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKI---MTELKKIAKERIVI 189
Cdd:PRK10982 386 RTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIyqlIAELAKKDKGIIII 447
PTZ00243 PTZ00243
ABC transporter; Provisional
 28-219 8.49e-06

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 49.39  E-value: 8.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   28 LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNqsmkrftkkelsdyyynSIGFIWQDyQLIEYLSVECNIdLVLSLSN 107
Cdd:PTZ00243  688 LTVVLGATGSGKSTLLQSLLSQFEISEGRVWAER-----------------SIAYVPQQ-AWIMNATVRGNI-LFFDEED 748

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  108 ---LNKAERKMKVAKVLEELGiSGLAKM---KVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTE--L 179
Cdd:PTZ00243  749 aarLADAVRVSQLEADLAQLG-GGLETEigeKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVGERVVEEcfL 827

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 736694016  180 KKIA-KERivIIVTHDKGLIEKDANVYSMEQGQLKLVGQSK 219
Cdd:PTZ00243  828 GALAgKTR--VLATHQVHVVPRADYVVALGDGRVEFSGSSA 866
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 25-224 9.29e-06

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 48.81  E-value: 9.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  25 QKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMkrfTKKELSDYYyNSIGFIWQDYQLIEYLsvecnidlvl 103
Cdd:PRK10522 347 KRGeLLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPV---TAEQPEDYR-KLFSAVFTDFHLFDQL---------- 412

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 104 sLSNLNKAERKMKVAKVLEELGISglAKMKVA-------KLSGGQKQRVAIARALVKDPEIIIADEptkaldlLAAN--- 173
Cdd:PRK10522 413 -LGPEGKPANPALVEKWLERLKMA--HKLELEdgrisnlKLSKGQKKRLALLLALAEERDILLLDE-------WAADqdp 482

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 736694016 174 --------KIMTELKKIAKerIVIIVTHDKGLIEKDANVYSMEQGQL-KLVGQSKQH-SKD 224
Cdd:PRK10522 483 hfrrefyqVLLPLLQEMGK--TIFAISHDDHYFIHADRLLEMRNGQLsELTGEERDAaSRD 541
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 26-193 1.12e-05

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 47.37  E-value: 1.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  26 KGLNF---------IYGPSGSGKTTLLNIISGmDQNFE---GDVYFNNQSM------KRFTKkelsdyyynSIGFIWQDY 87
Cdd:COG0396   17 KGVNLtikpgevhaIMGPNGSGKSTLAKVLMG-HPKYEvtsGSILLDGEDIlelspdERARA---------GIFLAFQYP 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  88 QLIEYLSvecNIDLVLSLSNlNKAERKMKVAKVLEELGisglAKMKVAKL-------------SGGQKQRVAIARALVKD 154
Cdd:COG0396   87 VEIPGVS---VSNFLRTALN-ARRGEELSAREFLKLLK----EKMKELGLdedfldryvnegfSGGEKKRNEILQMLLLE 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 736694016 155 PEIIIADEPTKALDLLAANKIMTELKKIA-KERIVIIVTH 193
Cdd:COG0396  159 PKLAILDETDSGLDIDALRIVAEGVNKLRsPDRGILIITH 198
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
137-220 1.56e-05

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 47.59  E-value: 1.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 137 LSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKER--IVIIVTHDKGLIEKDANVYS-MEQGQLK 213
Cdd:COG4170  159 LTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQgtSILLISHDLESISQWADTITvLYCGQTV 238


                 ....*..
gi 736694016 214 LVGQSKQ 220
Cdd:COG4170  239 ESGPTEQ 245
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 28-199 1.70e-05

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 45.78  E-value: 1.70e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  28 LNFIYGPSGSGKTTLLNIISgmdqnfegdvyfnNQSMKRFTKKELSDYYYNSIGFIWQDYQLIE----YLSVEcnidlvl 103
Cdd:cd03238   23 LVVVTGVSGSGKSTLVNEGL-------------YASGKARLISFLPKFSRNKLIFIDQLQFLIDvglgYLTLG------- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 104 slsnlnkaeRKMkvakvleelgisglakmkvAKLSGGQKQRVAIARALVKDPE--IIIADEPTKALDLLAANKIMTELKK 181
Cdd:cd03238   83 ---------QKL-------------------STLSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQDINQLLEVIKG 134

                        170
                 ....*....|....*....
gi 736694016 182 IAKE-RIVIIVTHDKGLIE 199
Cdd:cd03238  135 LIDLgNTVILIEHNLDVLS 153
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 16-192 2.56e-05

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 47.60  E-value: 2.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    16 VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQ-SMKRFTKKELSDYYYNSI--GFIWQDYQlie 91
Cdd:TIGR01271  441 VLKNISFKLEKGqLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGRiSFSPQTSWIMPGTIKDNIifGLSYDEYR--- 517

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    92 YLSV--ECNIDlvlslSNLNKAERKMKVakVLEELGISglakmkvakLSGGQKQRVAIARALVKDPEIIIADEPTKALDL 169
Cdd:TIGR01271  518 YTSVikACQLE-----EDIALFPEKDKT--VLGEGGIT---------LSGGQRARISLARAVYKDADLYLLDSPFTHLDV 581

                          170       180
                   ....*....|....*....|....
gi 736694016   170 LAANKIMTE-LKKIAKERIVIIVT 192
Cdd:TIGR01271  582 VTEKEIFEScLCKLMSNKTRILVT 605
LolE COG4591
ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall ...
 382-638 4.10e-05

ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443648 [Multi-domain]  Cd Length: 283  Bit Score: 45.68  E-value: 4.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 382 EVAVPKRLLDLLGLKptdvIGKNLNMTglidvnpkigsneITGSKVSLNDVKVVGVIEnnpkggaitstlgrRDGKLTDG 461
Cdd:COG4591   35 EVVLGEGLAKKLGLK----VGDTITLI-------------SPDGSPKTRRFTVVGIFE--------------SGGYELDG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 462 PLLFSveAIKKMRQQAGIEKSISY-NVRAKTLDDILPIVNKLQQ--SGLQPSGDFSMIEDMLRLRKkneeqgvTISLIFF 538
Cdd:COG4591   84 SLVYV--PLETAQELLGLGDQVSGiLVKLKDGADAEAVAAALEAalPGLEVKTWRELNAALFSALK-------TEKLILL 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 539 VLsLTISIVLALFNFYI--------KKSEFRFFKFNGFSNKNILSLIISEYFILGIMSSLL-FLITFPMLSLLSQKLFSI 609
Cdd:COG4591  155 LI-LLLILLVAAFNIVNtllmsvleRTREIGILKALGASRRQIRRIFLLEGLLLGLIGGLLgLLLGLLLALLLNALLGIL 233

                        250       260
                 ....*....|....*....|....*....
gi 736694016 610 YIVSTNNLVLVLLLPFVQSIIISILSYLL 638
Cdd:COG4591  234 LPFIFALPVSLSPSDVLLALLLALLISLL 262
PLN03232 PLN03232
ABC transporter C family member; Provisional
 121-224 4.67e-05

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 46.89  E-value: 4.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  121 LEELGISGLakmkvaKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTE-LKKIAKERIVIIVTHDKGLIE 199
Cdd:PLN03232  731 LTEIGERGV------NISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFDScMKDELKGKTRVLVTNQLHFLP 804

                          90       100
                  ....*....|....*....|....*
gi 736694016  200 KDANVYSMEQGQLKLVGQSKQHSKD 224
Cdd:PLN03232  805 LMDRIILVSEGMIKEEGTFAELSKS 829
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 136-207 5.70e-05

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 43.89  E-value: 5.70e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 736694016 136 KLSGGQKQRVAIARAL----VKDPEIIIADEPTKALDLLAANKIMTELKKIAKE-RIVIIVTHDKGLIEKDANVYSM 207
Cdd:cd03227   77 QLSGGEKELSALALILalasLKPRPLYILDEIDRGLDPRDGQALAEAILEHLVKgAQVIVITHLPELAELADKLIHI 153
VirB4_CagE TIGR00929
type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found ...
 19-69 7.55e-05

type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).


Pssm-ID: 273346 [Multi-domain]  Cd Length: 785  Bit Score: 46.16  E-value: 7.55e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 736694016   19 HLSGDFQKGLNFIYGPSGSGKTTLLNIISGMDQNFEGD--VYF-NNQSMKRFTK 69
Cdd:TIGR00929 427 HVRDAKVLGHTLIFGPTGSGKTTLLNFLLAQMQKYGGMtiFAFdKDRGMEIFIR 480
PLN03130 PLN03130
ABC transporter C family member; Provisional
 137-168 7.62e-05

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 46.27  E-value: 7.62e-05
                          10        20        30
                  ....*....|....*....|....*....|..
gi 736694016  137 LSGGQKQRVAIARALVKDPEIIIADEPTKALD 168
Cdd:PLN03130  741 ISGGQKQRVSMARAVYSNSDVYIFDDPLSALD 772
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 13-198 9.41e-05

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 45.51  E-value: 9.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   13 NEIVLNHLSGDFQKGLN-FIYGPSGSGKTTLLNIISGMDQNFEGdvyfnnqsmkRFTKKELSDYY------YNSIGFIWQ 85
Cdd:TIGR00954 464 GDVLIESLSFEVPSGNNlLICGPNGCGKSSLFRILGELWPVYGG----------RLTKPAKGKLFyvpqrpYMTLGTLRD 533

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   86 dyQLIEYLSVECNIDLVLSLSNLNKAERKMKVAKVLE-ELGISGLAKMKvAKLSGGQKQRVAIARALVKDPEIIIADEPT 164
Cdd:TIGR00954 534 --QIIYPDSSEDMKRRGLSDKDLEQILDNVQLTHILErEGGWSAVQDWM-DVLSGGEKQRIAMARLFYHKPQFAILDECT 610

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 736694016  165 KALDLLAANKIMTELKKIakeRIVII-VTHDKGLI 198
Cdd:TIGR00954 611 SAVSVDVEGYMYRLCREF---GITLFsVSHRKSLW 642
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 4-225 1.22e-04

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 45.16  E-value: 1.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   4 LIEIKKV---FGNEIVLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVyfnnqSMKRFTKkelsdyyyns 79
Cdd:PRK10636 312 LLKMEKVsagYGDRIILDSIKLNLVPGSRIgLLGRNGAGKSTLIKLLAGELAPVSGEI-----GLAKGIK---------- 376

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  80 IGFIWQdYQLiEYLSVECNidlvlSLSNLNKAERKMKVAKVLEELGISGLAKMKV----AKLSGGQKQRVAIARALVKDP 155
Cdd:PRK10636 377 LGYFAQ-HQL-EFLRADES-----PLQHLARLAPQELEQKLRDYLGGFGFQGDKVteetRRFSGGEKARLVLALIVWQRP 449

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 156 EIIIADEPTKALDlLAANKIMTElKKIAKERIVIIVTHDKGLIEKDAN-VYSMEQGQLK------------LVGQSKQHS 222
Cdd:PRK10636 450 NLLLLDEPTNHLD-LDMRQALTE-ALIDFEGALVVVSHDRHLLRSTTDdLYLVHDGKVEpfdgdledyqqwLSDVQKQEN 527


                 ...
gi 736694016 223 KDD 225
Cdd:PRK10636 528 QTD 530
GguA NF040905
sugar ABC transporter ATP-binding protein;
133-191 1.23e-04

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 45.17  E-value: 1.23e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 736694016 133 KVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIV 191
Cdd:NF040905 401 KVGNLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIV 459
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 16-192 1.43e-04

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 44.08  E-value: 1.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  16 VLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEGD------VYFNNQS--MKRFTKKElsdyyyNSI-GFIWQ 85
Cdd:cd03291   52 VLKNINLKIEKGeMLAITGSTGSGKTSLLMLILGELEPSEGKikhsgrISFSSQFswIMPGTIKE------NIIfGVSYD 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  86 DYQlieYLSV--ECNIDlvlslSNLNKAERKMKVakVLEELGISglakmkvakLSGGQKQRVAIARALVKDPEIIIADEP 163
Cdd:cd03291  126 EYR---YKSVvkACQLE-----EDITKFPEKDNT--VLGEGGIT---------LSGGQRARISLARAVYKDADLYLLDSP 186

                        170       180       190
                 ....*....|....*....|....*....|
gi 736694016 164 TKALDLLAANKIMTE-LKKIAKERIVIIVT 192
Cdd:cd03291  187 FGYLDVFTEKEIFEScVCKLMANKTRILVT 216
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 8-195 1.54e-04

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 44.88  E-value: 1.54e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   8 KKVFGNEIVLNHLSGDFQ-----KGLNF---------IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSmkrftkkels 73
Cdd:PRK15064 313 KKLHRNALEVENLTKGFDngplfKNLNLlleagerlaIIGENGVGKTTLLRTLVGELEPDSGTVKWSENA---------- 382

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  74 dyyynSIGFIWQDYqlieYLSVECNIDLVLSLSNLNKAER-KMKVAKVLEELGISG-LAKMKVAKLSGGQKQRVAIARAL 151
Cdd:PRK15064 383 -----NIGYYAQDH----AYDFENDLTLFDWMSQWRQEGDdEQAVRGTLGRLLFSQdDIKKSVKVLSGGEKGRMLFGKLM 453

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 736694016 152 VKDPEIIIADEPTKALDLLAANKIMTELKKIakERIVIIVTHDK 195
Cdd:PRK15064 454 MQKPNVLVMDEPTNHMDMESIESLNMALEKY--EGTLIFVSHDR 495
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 137-216 1.68e-04

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 44.94  E-value: 1.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   137 LSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIVTHDKGLIEKDANVYSMEQGQLKLVG 216
Cdd:TIGR00957 1422 LSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEVAEFG 1501
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
23-194 1.89e-04

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 43.08  E-value: 1.89e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  23 DFQKGLNFIYGPSGSGKTTLLNIIS-GMDQNFEGDVYFNNQSMKRFTKK-------ELSDYYYNsigFIWQDYQLIEYLS 94
Cdd:COG0419   20 DFDDGLNLIVGPNGAGKSTILEAIRyALYGKARSRSKLRSDLINVGSEEasvelefEHGGKRYR---IERRQGEFAEFLE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  95 VECN--IDLVLSLSNLNKAERKMKVAKVLEELGISGLAKMK------------------VAKLSGGQKQRVAIARALvkd 154
Cdd:COG0419   97 AKPSerKEALKRLLGLEIYEELKERLKELEEALESALEELAelqklkqeilaqlsgldpIETLSGGERLRLALADLL--- 173

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 736694016 155 pEIIIaDepTKALDLLAANKIMTELKKIAkeriviIVTHD 194
Cdd:COG0419  174 -SLIL-D--FGSLDEERLERLLDALEELA------IITHV 203
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
130-191 2.68e-04

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 44.13  E-value: 2.68e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 736694016 130 AKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVIIV 191
Cdd:PRK11288 390 REQLIMNLSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQGVAVLF 451
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 5-168 2.81e-04

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 44.16  E-value: 2.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016    5 IEIK---KVFGNEIVLNHLSGDFQKG-LNFIYGPSGSGKTTLLNIISGMDQNFEG--------DVYFNNQSMKRFTKKEL 72
Cdd:TIGR03719 323 IEAEnltKAFGDKLLIDDLSFKLPPGgIVGVIGPNGAGKSTLFRMITGQEQPDSGtieigetvKLAYVDQSRDALDPNKT 402

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   73 sdyyynsigfIWQD----YQLIEYLSVECNIDLVLSLSNLNKAERkmkvakvleelgisglaKMKVAKLSGGQKQRVAIA 148
Cdd:TIGR03719 403 ----------VWEEisggLDIIKLGKREIPSRAYVGRFNFKGSDQ-----------------QKKVGQLSGGERNRVHLA 455

                         170       180
                  ....*....|....*....|
gi 736694016  149 RALVKDPEIIIADEPTKALD 168
Cdd:TIGR03719 456 KTLKSGGNVLLLDEPTNDLD 475
RloC COG4694
Wobble nucleotide-excising tRNase [Translation, ribosomal structure and biogenesis];
26-202 2.97e-04

Wobble nucleotide-excising tRNase [Translation, ribosomal structure and biogenesis];


Pssm-ID: 443729 [Multi-domain]  Cd Length: 692  Bit Score: 43.96  E-value: 2.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  26 KGLNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSDYY-YNS----IGFIWQDYQLIEYLSVECNID 100
Cdd:COG4694   24 KKLNLIYGENGSGKSTLSRILRSLELGDTSSEVIAEFEIEAGGSAPNPSVRvFNRdfveENLRSGEEIKGIFTLGEENIE 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 101 -------LVLSLSNLNKAERKMK---------VAKVLEELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPT 164
Cdd:COG4694  104 leeeieeLEKEIEDLKKELDKLEkelkeakkaLEKLLEDLAKSIKDDLKKLFASSGRNYRKANLEKKLSALKSSSEDELK 183

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 736694016 165 KALDLLAANKIMTELKKIAKERIVIIVTHDKGLIEKDA 202
Cdd:COG4694  184 EKLKLLKEEEPEPIAPITPLPDLKALLSEAETLLEKSA 221
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 1-168 3.39e-04

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 42.17  E-value: 3.39e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016   1 MLSLIEIKKVFGNEIVLNHLSGDFQKGLNFIYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELsdyyynsi 80
Cdd:PRK13541   1 MLSLHQLQFNIEQKNLFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIAKPYC-------- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  81 GFIWQDYQLIEYLSVECNI----DLVLSLSNLNKAERKMKVAKVLEElgisglakmKVAKLSGGQKQRVAIARALVKDPE 156
Cdd:PRK13541  73 TYIGHNLGLKLEMTVFENLkfwsEIYNSAETLYAAIHYFKLHDLLDE---------KCYSLSSGMQKIVAIARLIACQSD 143

                        170
                 ....*....|..
gi 736694016 157 IIIADEPTKALD 168
Cdd:PRK13541 144 LWLLDEVETNLS 155
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
33-203 3.56e-04

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 43.25  E-value: 3.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  33 GPSGSGKTTLLNIISGMDQ---NFEGDVY-FNNQSMKRFTKKELSDYYYNSIGFIWQDYQLIEYLSVECNIDLVLSLSNL 108
Cdd:PRK15093  40 GESGSGKSLIAKAICGVTKdnwRVTADRMrFDDIDLLRLSPRERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPGW 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016 109 N-KAE-------RKMKVAKVLEELGISGLAKMKVA---KLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMT 177
Cdd:PRK15093 120 TyKGRwwqrfgwRKRRAIELLHRVGIKDHKDAMRSfpyELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFR 199

                        170       180
                 ....*....|....*....|....*...
gi 736694016 178 ELKKIAKER--IVIIVTHDKGLIEKDAN 203
Cdd:PRK15093 200 LLTRLNQNNntTILLISHDLQMLSQWAD 227
FtsX pfam02687
FtsX-like permease family; This is a family of predicted permeases and hypothetical ...
 533-644 4.22e-04

FtsX-like permease family; This is a family of predicted permeases and hypothetical transmembrane proteins. Swiss:P57382 has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both Swiss:P57382 and Swiss:O54500 have been shown to require ATP. This region contains three transmembrane helices.


Pssm-ID: 460652 [Multi-domain]  Cd Length: 120  Bit Score: 40.31  E-value: 4.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  533 ISLIFFVLSLTISIVLALFNFYI--KKSEFRFFKFNGFSNKNILSLIISEYFILGIMSSLL-FLITFPMLSLLSQKLFS- 608
Cdd:pfam02687   1 ILFSLLILLLAVLIILLLLSISIseRRREIGILRALGASRKQIFKLLLLEALLIGLIGLVIgLLLGLLLAKLIAILLYSs 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 736694016  609 ----IYIVSTNNLVLVLLLPFVQSIIISILSYLLFLKTNP 644
Cdd:pfam02687  81 gislPILVPPLSILIALLLALLIALLASLLPALRIRKINP 120
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 122-190 4.84e-04

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 43.08  E-value: 4.84e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 736694016 122 EELGISGLAKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLLAANKIMTELKKIAKERIVII 190
Cdd:PRK10938 121 QQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLASLHQSGITLV 189
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 16-193 6.41e-04

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 42.20  E-value: 6.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  16 VLNHLSGDFQKGLNF-IYGPSGSGKTTLLNIISGMDQNFEGDVYFNNQSMKRFTKKELSdyyyNSIGFIWQDYQLIEYlS 94
Cdd:cd03288   36 VLKHVKAYIKPGQKVgICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLR----SRLSIILQDPILFSG-S 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736694016  95 VECNIDlvlslsnlnkAERKMKVAKVLEELGISGLAKMkVAKLSGG---------------QKQRVAIARALVKDPEIII 159
Cdd:cd03288  111 IRFNLD----------PECKCTDDRLWEALEIAQLKNM-VKSLPGGldavvteggenfsvgQRQLFCLARAFVRKSSILI 179

                        170       180       190
                 ....*....|....*....|....*....|....
gi 736694016 160 ADEPTKALDLLAANKIMTELKKIAKERIVIIVTH 193
Cdd:cd03288  180 MDEATASIDMATENILQKVVMTAFADRTVVTIAH 213
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 130-199 1.73e-03

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 41.47  E-value: 1.73e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 736694016 130 AKMKVAKLSGGQKQRVAIARALVKDPEIIIADEPTKALDLlaankimtELKKIAKERI------VIIVTHDKGLIE 199
Cdd:PRK11147 434 AMTPVKALSGGERNRLLLARLFLKPSNLLILDEPTNDLDV--------ETLELLEELLdsyqgtVLLVSHDRQFVD 501
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
19-49 2.90e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.91  E-value: 2.90e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 736694016  19 HLSGDFQKGLNFIYGPSGSGKTTLLNIISGM 49
Cdd:COG4717   16 DRTIEFSPGLNVIYGPNEAGKSTLLAFIRAM 46
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 140-195 3.09e-03

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 40.65  E-value: 3.09e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 736694016 140 GQKQRVAIARALVKDPEIIIADEPTKALDLlaaNKImTELKKIAKER--IVIIVTHDK 195
Cdd:PRK15064 159 GWKLRVLLAQALFSNPDILLLDEPTNNLDI---NTI-RWLEDVLNERnsTMIIISHDR 212
AAA_23 pfam13476
AAA domain;
23-46 3.93e-03

AAA domain;


Pssm-ID: 463890 [Multi-domain]  Cd Length: 190  Bit Score: 39.02  E-value: 3.93e-03
                          10        20
                  ....*....|....*....|....
gi 736694016   23 DFQKGLNFIYGPSGSGKTTLLNII 46
Cdd:pfam13476  15 DFSKGLTLITGPNGSGKTTILDAI 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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