NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|754158850|ref|WP_041781015|]
View 

CoA-binding protein [Allocoleopsis franciscana]

Protein Classification

SucD family protein( domain architecture ID 11414657)

SucD family protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SucD COG0074
Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA ...
 3-295 5.83e-140

Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA synthetase, alpha subunit is part of the Pathway/BioSystem: TCA cycle


:

Pssm-ID: 439844 [Multi-domain]  Cd Length: 288  Bit Score: 395.97  E-value: 5.83e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850   3 LTPNSKVLVQGITQPLGSYYTARMKAYGTNVVAGVSAGQGGQELHGIPVFDLVEQVLPQTGpIEASIIFVESYRVLDAAL 82
Cdd:COG0074    4 VNKNTRVIVQGITGKEGSFHTKQMLAYGTNVVAGVTPGKGGQTVLGVPVFDTVAEAVEETG-ADASVIFVPPPFAADAIL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850  83 EAMDAEIPLIILVTEGVPPLDMVRLLRKAEATGTVIVGPSSSGIIVPGKVLLGAQESEFYTPGPVGLIARAGALAYEVAL 162
Cdd:COG0074   83 EAIDAGIKLIVCITEGIPVLDMVRVKRYAKAKGTRLIGPNCPGIITPGECKLGIMPGHIFKPGRVGIVSRSGTLTYEAVW 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850 163 GLTHAKLGQSMAVNLGSAAIVGSSFCQWLQILAMDKSTKVIVLVDQTGGLSDDATAEYIAQAIDKPVIAYVAGSYTPLDK 242
Cdd:COG0074  163 QLTQAGLGQSTCVGIGGDPIIGTSFIDVLELFEEDPETEAIVMIGEIGGSAEEEAAEYIKENMTKPVVAYIAGRTAPPGK 242

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 754158850 243 QISDASAIIAaqlsgpiTNASTAQHKVAAFKQANIPVAERPSQIPELVRKALK 295
Cdd:COG0074  243 RMGHAGAIIS-------GGKGTAESKIEALEAAGVPVAESPSEIGELLKKALK 288
 
Name Accession Description Interval E-value
SucD COG0074
Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA ...
 3-295 5.83e-140

Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA synthetase, alpha subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 439844 [Multi-domain]  Cd Length: 288  Bit Score: 395.97  E-value: 5.83e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850   3 LTPNSKVLVQGITQPLGSYYTARMKAYGTNVVAGVSAGQGGQELHGIPVFDLVEQVLPQTGpIEASIIFVESYRVLDAAL 82
Cdd:COG0074    4 VNKNTRVIVQGITGKEGSFHTKQMLAYGTNVVAGVTPGKGGQTVLGVPVFDTVAEAVEETG-ADASVIFVPPPFAADAIL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850  83 EAMDAEIPLIILVTEGVPPLDMVRLLRKAEATGTVIVGPSSSGIIVPGKVLLGAQESEFYTPGPVGLIARAGALAYEVAL 162
Cdd:COG0074   83 EAIDAGIKLIVCITEGIPVLDMVRVKRYAKAKGTRLIGPNCPGIITPGECKLGIMPGHIFKPGRVGIVSRSGTLTYEAVW 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850 163 GLTHAKLGQSMAVNLGSAAIVGSSFCQWLQILAMDKSTKVIVLVDQTGGLSDDATAEYIAQAIDKPVIAYVAGSYTPLDK 242
Cdd:COG0074  163 QLTQAGLGQSTCVGIGGDPIIGTSFIDVLELFEEDPETEAIVMIGEIGGSAEEEAAEYIKENMTKPVVAYIAGRTAPPGK 242

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 754158850 243 QISDASAIIAaqlsgpiTNASTAQHKVAAFKQANIPVAERPSQIPELVRKALK 295
Cdd:COG0074  243 RMGHAGAIIS-------GGKGTAESKIEALEAAGVPVAESPSEIGELLKKALK 288
PRK05678 PRK05678
succinyl-CoA synthetase subunit alpha; Validated
 3-296 1.10e-86

succinyl-CoA synthetase subunit alpha; Validated


Pssm-ID: 180194 [Multi-domain]  Cd Length: 291  Bit Score: 260.87  E-value: 1.10e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850   3 LTPNSKVLVQGITQPLGSYYTARMKAYGTNVVAGVSAGQGGQELHGIPVFDLVEQVLPQTGPiEASIIFVESYRVLDAAL 82
Cdd:PRK05678   5 INKDTKVIVQGITGKQGTFHTEQMLAYGTNIVGGVTPGKGGTTVLGLPVFNTVAEAVEATGA-NASVIYVPPPFAADAIL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850  83 EAMDAEIPLIILVTEGVPPLDMVRLLRKAEATGTVIVGPSSSGIIVPGKVLLGAQESEFYTPGPVGLIARAGALAYEVAL 162
Cdd:PRK05678  84 EAIDAGIDLIVCITEGIPVLDMLEVKAYLERKKTRLIGPNCPGIITPGECKIGIMPGHIHKKGRVGVVSRSGTLTYEAVA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850 163 GLTHAKLGQSMAVNLGSAAIVGSSFCQWLQILAMDKSTKVIVLVDQTGGLSDDATAEYIAQAIDKPVIAYVAGSYTPLDK 242
Cdd:PRK05678 164 QLTDLGFGQSTCVGIGGDPINGTNFIDVLEAFEEDPETEAIVMIGEIGGSAEEEAAEYIKANVTKPVVGYIAGVTAPPGK 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 754158850 243 QISDASAIIaaqlSGpitNASTAQHKVAAFKQANIPVAERPSQIPELVRKALKK 296
Cdd:PRK05678 244 RMGHAGAII----SG---GKGTAEEKKEALEAAGVKVARTPSEIGELLKEVLKG 290
CoA_binding pfam02629
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 6-98 2.80e-19

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 396961 [Multi-domain]  Cd Length: 97  Bit Score: 80.71  E-value: 2.80e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850    6 NSKVLVQGIT---QPLGSYYTARMKAYGTNVVAGVSAGQGGQELHGIPVFDLVEQvLPQTGPIEASIIFVESYRVLDAAL 82
Cdd:pfam02629   3 DTKVIVIGAGglgIQGLNYHFIQMLGYGIKMVFGVNPGKGGTEILGIPVYNSVDE-LEEKTGVDVAVITVPAPFAQEAID 81

                          90
                  ....*....|....*.
gi 754158850   83 EAMDAEIPLIILVTEG 98
Cdd:pfam02629  82 ELVDAGIKGIVNITPG 97
CoA_binding smart00881
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 3-99 3.98e-18

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 214881 [Multi-domain]  Cd Length: 100  Bit Score: 77.55  E-value: 3.98e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850     3 LTPNSKVLVQGITQPLGSYYTARMKA---YGTNVVAGVSAGQGGQELHGIPVFDLVEQvLPQTGPIEASIIFVESYRVLD 79
Cdd:smart00881   2 LNPNTSVAVVGASGNLGSFGLAVMRNlleYGTKFVGGVYPGKVGPKVDGVPVYDSVAE-APEETGVDVAVIFVPAEAAPD 80

                           90       100
                   ....*....|....*....|
gi 754158850    80 AALEAMDAEIPLIILVTEGV 99
Cdd:smart00881  81 AIDEAIEAGIKGIVVITEGI 100
 
Name Accession Description Interval E-value
SucD COG0074
Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA ...
 3-295 5.83e-140

Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA synthetase, alpha subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 439844 [Multi-domain]  Cd Length: 288  Bit Score: 395.97  E-value: 5.83e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850   3 LTPNSKVLVQGITQPLGSYYTARMKAYGTNVVAGVSAGQGGQELHGIPVFDLVEQVLPQTGpIEASIIFVESYRVLDAAL 82
Cdd:COG0074    4 VNKNTRVIVQGITGKEGSFHTKQMLAYGTNVVAGVTPGKGGQTVLGVPVFDTVAEAVEETG-ADASVIFVPPPFAADAIL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850  83 EAMDAEIPLIILVTEGVPPLDMVRLLRKAEATGTVIVGPSSSGIIVPGKVLLGAQESEFYTPGPVGLIARAGALAYEVAL 162
Cdd:COG0074   83 EAIDAGIKLIVCITEGIPVLDMVRVKRYAKAKGTRLIGPNCPGIITPGECKLGIMPGHIFKPGRVGIVSRSGTLTYEAVW 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850 163 GLTHAKLGQSMAVNLGSAAIVGSSFCQWLQILAMDKSTKVIVLVDQTGGLSDDATAEYIAQAIDKPVIAYVAGSYTPLDK 242
Cdd:COG0074  163 QLTQAGLGQSTCVGIGGDPIIGTSFIDVLELFEEDPETEAIVMIGEIGGSAEEEAAEYIKENMTKPVVAYIAGRTAPPGK 242

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 754158850 243 QISDASAIIAaqlsgpiTNASTAQHKVAAFKQANIPVAERPSQIPELVRKALK 295
Cdd:COG0074  243 RMGHAGAIIS-------GGKGTAESKIEALEAAGVPVAESPSEIGELLKKALK 288
PRK05678 PRK05678
succinyl-CoA synthetase subunit alpha; Validated
 3-296 1.10e-86

succinyl-CoA synthetase subunit alpha; Validated


Pssm-ID: 180194 [Multi-domain]  Cd Length: 291  Bit Score: 260.87  E-value: 1.10e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850   3 LTPNSKVLVQGITQPLGSYYTARMKAYGTNVVAGVSAGQGGQELHGIPVFDLVEQVLPQTGPiEASIIFVESYRVLDAAL 82
Cdd:PRK05678   5 INKDTKVIVQGITGKQGTFHTEQMLAYGTNIVGGVTPGKGGTTVLGLPVFNTVAEAVEATGA-NASVIYVPPPFAADAIL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850  83 EAMDAEIPLIILVTEGVPPLDMVRLLRKAEATGTVIVGPSSSGIIVPGKVLLGAQESEFYTPGPVGLIARAGALAYEVAL 162
Cdd:PRK05678  84 EAIDAGIDLIVCITEGIPVLDMLEVKAYLERKKTRLIGPNCPGIITPGECKIGIMPGHIHKKGRVGVVSRSGTLTYEAVA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850 163 GLTHAKLGQSMAVNLGSAAIVGSSFCQWLQILAMDKSTKVIVLVDQTGGLSDDATAEYIAQAIDKPVIAYVAGSYTPLDK 242
Cdd:PRK05678 164 QLTDLGFGQSTCVGIGGDPINGTNFIDVLEAFEEDPETEAIVMIGEIGGSAEEEAAEYIKANVTKPVVGYIAGVTAPPGK 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 754158850 243 QISDASAIIaaqlSGpitNASTAQHKVAAFKQANIPVAERPSQIPELVRKALKK 296
Cdd:PRK05678 244 RMGHAGAII----SG---GKGTAEEKKEALEAAGVKVARTPSEIGELLKEVLKG 290
PTZ00187 PTZ00187
succinyl-CoA synthetase alpha subunit; Provisional
 6-296 1.22e-57

succinyl-CoA synthetase alpha subunit; Provisional


Pssm-ID: 240307 [Multi-domain]  Cd Length: 317  Bit Score: 187.61  E-value: 1.22e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850   6 NSKVLVQGITQPLGSYYTARMKAYGTNVVAGVSAGQGGQ--ELHGIPVFDLVEQVLPQTGPiEASIIFVESYRVLDAALE 83
Cdd:PTZ00187  29 NTKVICQGITGKQGTFHTEQAIEYGTKMVGGVNPKKAGTthLKHGLPVFATVKEAKKATGA-DASVIYVPPPHAASAIIE 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850  84 AMDAEIPLIILVTEGVPPLDMVRLLRKAEATG-TVIVGPSSSGIIVPGKVLLGAQESEFYTPGPVGLIARAGALAYEVAL 162
Cdd:PTZ00187 108 AIEAEIPLVVCITEGIPQHDMVKVKHALLSQNkTRLIGPNCPGIIKPGECKIGIMPGHIHKKGKIGIVSRSGTLTYEAVA 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850 163 GLTHAKLGQSMAVNLGSAAIVGSSFCQWLQILAMDKSTKVIVLVDQTGGLSDDATAEYIAQ-AIDKPVIAYVAGSYTPLD 241
Cdd:PTZ00187 188 QTTAVGLGQSTCVGIGGDPFNGTNFIDCLKLFLNDPETEGIILIGEIGGTAEEEAAEWIKNnPIKKPVVSFIAGITAPPG 267

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 754158850 242 KQISDASAIIaaqlSGpitNASTAQHKVAAFKQANIPVAERPSQIPELVRKALKK 296
Cdd:PTZ00187 268 RRMGHAGAII----SG---GKGTAPGKIEALEAAGVRVVKSPAQLGKTMLEVMKK 315
PLN00125 PLN00125
Succinyl-CoA ligase [GDP-forming] subunit alpha
 6-295 1.45e-54

Succinyl-CoA ligase [GDP-forming] subunit alpha


Pssm-ID: 215066 [Multi-domain]  Cd Length: 300  Bit Score: 179.39  E-value: 1.45e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850   6 NSKVLVQGITQPLGSYYTARMKAYGTNVVAGVSAGQGGQELHGIPVFDLVEQVLPQTGPiEASIIFVESYRVLDAALEAM 85
Cdd:PLN00125  12 NTRVICQGITGKNGTFHTEQAIEYGTKMVGGVTPKKGGTEHLGLPVFNTVAEAKAETKA-NASVIYVPPPFAAAAILEAM 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850  86 DAEIPLIILVTEGVPPLDMVRLLRK-AEATGTVIVGPSSSGIIVPGKVLLGAQESEFYTPGPVGLIARAGALAYEVALGL 164
Cdd:PLN00125  91 EAELDLVVCITEGIPQHDMVRVKAAlNRQSKTRLIGPNCPGIIKPGECKIGIMPGYIHKPGRIGIVSRSGTLTYEAVFQT 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850 165 THAKLGQSMAVNLGSAAIVGSSFCQWLQILAMDKSTKVIVLVDQTGGLSDDATAEYI-AQAIDKPVIAYVAGSYTPLDKQ 243
Cdd:PLN00125 171 TAVGLGQSTCVGIGGDPFNGTNFVDCLEKFVKDPQTEGIILIGEIGGTAEEDAAAFIkESGTEKPVVAFIAGLTAPPGRR 250

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 754158850 244 ISDASAIIAAqlsgpitNASTAQHKVAAFKQANIPVAERPSQIPELVRKALK 295
Cdd:PLN00125 251 MGHAGAIVSG-------GKGTAQDKIKALREAGVTVVESPAKIGVAMLEVFK 295
CoA_binding pfam02629
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 6-98 2.80e-19

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 396961 [Multi-domain]  Cd Length: 97  Bit Score: 80.71  E-value: 2.80e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850    6 NSKVLVQGIT---QPLGSYYTARMKAYGTNVVAGVSAGQGGQELHGIPVFDLVEQvLPQTGPIEASIIFVESYRVLDAAL 82
Cdd:pfam02629   3 DTKVIVIGAGglgIQGLNYHFIQMLGYGIKMVFGVNPGKGGTEILGIPVYNSVDE-LEEKTGVDVAVITVPAPFAQEAID 81

                          90
                  ....*....|....*.
gi 754158850   83 EAMDAEIPLIILVTEG 98
Cdd:pfam02629  82 ELVDAGIKGIVNITPG 97
CoA_binding smart00881
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 3-99 3.98e-18

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 214881 [Multi-domain]  Cd Length: 100  Bit Score: 77.55  E-value: 3.98e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850     3 LTPNSKVLVQGITQPLGSYYTARMKA---YGTNVVAGVSAGQGGQELHGIPVFDLVEQvLPQTGPIEASIIFVESYRVLD 79
Cdd:smart00881   2 LNPNTSVAVVGASGNLGSFGLAVMRNlleYGTKFVGGVYPGKVGPKVDGVPVYDSVAE-APEETGVDVAVIFVPAEAAPD 80

                           90       100
                   ....*....|....*....|
gi 754158850    80 AALEAMDAEIPLIILVTEGV 99
Cdd:smart00881  81 AIDEAIEAGIKGIVVITEGI 100
PLN02522 PLN02522
ATP citrate (pro-S)-lyase
 43-297 6.26e-15

ATP citrate (pro-S)-lyase


Pssm-ID: 178137 [Multi-domain]  Cd Length: 608  Bit Score: 74.86  E-value: 6.26e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850  43 GQELHGIPVFDLVEQVLPQTGPIEASIIFVESYRVLDAALEAMDAE-IPLIILVTEGVPPLDMVRLLRKAEATGTVIVGP 121
Cdd:PLN02522  57 GQEEIAIPVHGSIEAACKAHPTADVFINFASFRSAAASSMEALKQPtIRVVAIIAEGVPESDTKQLIAYARANNKVVIGP 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850 122 SSSGIIVPGKVLLGAQ--------ESEFYTPGPVGLIARAGALAYEVALGLTHAKLGQSMAVNLGSAAIVGSSFCQWLQI 193
Cdd:PLN02522 137 ATVGGIQAGAFKIGDTagtldniiQCKLYRPGSVGFVSKSGGMSNEMYNVIARVTDGIYEGIAIGGDVFPGSTLSDHVLR 216

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850 194 LAMDKSTKVIVLVDQTGGLSDDATAEYIAQ-AIDKPVIAYVAGSYTPLDK---QISDASAIIAAQLsgpitnaSTAQHKV 269
Cdd:PLN02522 217 FNNIPQIKMIVVLGELGGRDEYSLVEALKQgKVSKPVVAWVSGTCARLFKsevQFGHAGAKSGGDM-------ESAQAKN 289

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 754158850 270 AAFKQAN---------------------------IPVAE-RPSQIPELVRKALKKG 297
Cdd:PLN02522 290 KALKDAGaivptsfealeaaiketfeklveegkiIPVKEvTPPQIPEDLNSAIKSG 345
Succ_CoA_lig pfam13607
Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from ...
 144-285 6.19e-08

Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from Succinyl-CoA ligase alpha subunit and other related enzymes. A conserved histidine is involved in phosphoryl transfer.


Pssm-ID: 433345 [Multi-domain]  Cd Length: 138  Bit Score: 50.54  E-value: 6.19e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850  144 PGPVGLIARAGALAYEVALGLTHAKLGQSMAVNLGSAAIVgsSFCQWLQILAMDKSTKVIVL----VDQTGGLSDdaTAE 219
Cdd:pfam13607   1 PGNIALVSQSGALGAALLDWARSRGIGFSKFVSLGNEADV--DFADLLEYLADDPETRVILLylegIRDGRRFLR--AAR 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754158850  220 YIAQAidKPVIAYVAGSytpldkqiSDASAIIAAQLSGpitnASTAQHKV--AAFKQANIPVAERPSQ 285
Cdd:pfam13607  77 RAARR--KPVVVLKAGR--------SEAGARAAASHTG----ALAGSDAVydAAFRQAGVIRVDDLEE 130
PatZN COG1042
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
43-277 1.33e-07

Acyl-CoA synthetase (NDP forming) [Energy production and conversion];


Pssm-ID: 440664 [Multi-domain]  Cd Length: 708  Bit Score: 52.43  E-value: 1.33e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850  43 GQELHGIPVFDLVEQvLPQtgPIEASIIFVESYRVLDAALEAMDAEIPLIILVT--------EGVPPLDmvRLLRKAEAT 114
Cdd:COG1042   51 YDEVLGLPCYPSVAD-LPE--PPDLAVIAVPAETVPDVVEECGEKGVKAAVVISagfaetgeEGAALEQ--ELLEIARRY 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850 115 GTVIVGPSSSGIIVPGKVLLGAQESEFYTPGPVGLIARAGALAYEVALGLTHAKLGQSMAVNLGSAAIVgsSFCQWLQIL 194
Cdd:COG1042  126 GMRLLGPNCLGLINPATGLNATFAPVPPLPGNIALVSQSGALGTAILDWAAARGIGFSHFVSLGNEADV--DFADLLDYL 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850 195 AMDKSTKVIVL-VDqtgGLSDD----ATAEYIAQaiDKPVIAYVAGSytpldkqiSDASAIIAAQLSGPITNAstaqHKV 269
Cdd:COG1042  204 ADDPDTRVILLyLE---GIRDGrrflSAARAAAR--GKPVVVLKSGR--------SEAGARAAASHTGALAGS----DAV 266

                        250
                 ....*....|
gi 754158850 270 --AAFKQANI 277
Cdd:COG1042  267 ydAAFRRAGV 276
Ligase_CoA pfam00549
CoA-ligase; This family includes the CoA ligases Succinyl-CoA synthetase alpha and beta chains, ...
 150-255 2.93e-06

CoA-ligase; This family includes the CoA ligases Succinyl-CoA synthetase alpha and beta chains, malate CoA ligase and ATP-citrate lyase. Some members of the family utilize ATP others use GTP.


Pssm-ID: 395434 [Multi-domain]  Cd Length: 128  Bit Score: 45.71  E-value: 2.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850  150 IARAGALAYEVALGLTHAKLGQSMAVNLGSAAIVGSSFCQWLQILAMDKSTKVIVLVDQTG-GLSDDATAEYI-----AQ 223
Cdd:pfam00549   1 LVNGGTLAMEAMDLIKLAGGGPHNFIDLGGDAFTPTTRIDALKLEAADPEVKVILLDIVLGyGACEDPAGGLLkaikeAR 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 754158850  224 AIDKPVIAYVAGSYTPLDKQISDASAIIAAQL 255
Cdd:pfam00549  81 ARELPVVARVCGTEADPQGRSGQAKALAESGV 112
PRK06091 PRK06091
membrane protein FdrA; Validated
 84-270 3.12e-05

membrane protein FdrA; Validated


Pssm-ID: 180395 [Multi-domain]  Cd Length: 555  Bit Score: 45.04  E-value: 3.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850  84 AMDAEIPL-----IILVTEGVPPLDMVRLLRKAEATGTVIVGPSSSGIIVPGKVLLGAQeseFYTPGPVGLIARAGALAY 158
Cdd:PRK06091 131 AELAEQALdrnlnVMMFSDNVTLEDEIRLKTRAREKGLLVMGPDCGTAMIAGTPLAFAN---VMPEGNIGVIGASGTGIQ 207

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754158850 159 EVALGLTHAKLGQSMAVNLG----SAAIVGSSFCQWLQILAMDKSTKVIVLVDQTGGLSDDATAEYIAQAIDKPVIAYVA 234
Cdd:PRK06091 208 ELCSQIALAGEGITHAIGLGgrdlSAEVGGISALTALEMLSADEKSEVIAFVSKPPAEAVRLKIINAMKATGKPVVALFL 287

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 754158850 235 GSYTPLDKQIS-------DASAIIAAQLSgPITNASTAQHKVA 270
Cdd:PRK06091 288 GYTPAVARDENvwfastlDEAARLACLLS-RVTAQRNAILPVS 329
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH