|
Name |
Accession |
Description |
Interval |
E-value |
| secD |
PRK12933 |
protein translocase subunit SecD; |
32-596 |
0e+00 |
|
protein translocase subunit SecD;
Pssm-ID: 183831 [Multi-domain] Cd Length: 604 Bit Score: 643.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 32 AMPNLYQNKTQLSISAlpQAQTLPSPDTLVHLLQSHGFSVAQI-GSGEPTLVTLTSQTASASAQAVLAEALRDQATVKVV 110
Cdd:PRK12933 32 AIPTWYGEDAAVQVSA--KAGLLLNVVELRQLLQAQGINVKRIdQKEGKTLIVLDDDSQQSQAKTLLSSMVKEPKELTLS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 111 EQATAPYWLQRLGLSPIKLGLDLNGGVLFVLKVDTDKALEKRMENIALEAKsQRIRDK-LKGVRIERSSVAGLElVALPQ 189
Cdd:PRK12933 110 LASAAPKWLQNMGFSPIKLGLDLRGGVQFLLDVDVDPVYQEQRDALVDSVR-QFLREQrIRGVSVRLDDSDQLA-VTTPD 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 190 gAAALQQLQTTLLAQFQHLSVQTHKhGNLLRATLSYDEagKAAFEKQTMTQALTTLRSRIEELGITEAVTQRQGANYIRI 269
Cdd:PRK12933 188 -NDARSAVRQFIQQNYPGWQVTNSD-DRGLQLKLSQQE--KTKFRNLTVQQNLQIMRSRIEELGITEALVQRQGEHRIRI 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 270 ELPGVQDPAAAKRIIGATAQLSFHALQEFG---GKRVKAEHGI-VGLDPLAIFTGADIDSAQAGRDEYGKPLVQLFLSSR 345
Cdd:PRK12933 264 ELPGVQDPAAAKNVIGATASLAFYEVKESGsvnAKVLKDKNGRpVYVARRPVLGGEHIVDARASLGEMGMAEVNISLDRA 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 346 GGDKMLRFSRANVGEPMATMYSEYIADSRGDIRQSSQVISVATIQQVLGQRFSITNLGSWQKAQDLALLLRAGSLDAPLT 425
Cdd:PRK12933 344 GGKKMSDFSRDNIGKPMATSYSEYSRDEQGKTKQSEEVISVATIQSQLGDRFRITGAGSYQEAQQLALLLRAGSLTAPVT 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 426 IVTERTIGPNLGAQNIASGFGALALGLSLTLGFMLLWYRKLGVIACMALVANLVCLVGLMSLLPGVVLTLPGIAGLVLTI 505
Cdd:PRK12933 424 IVEERTIGPSLGAENIENGFAALALGMGITLLFMALWYRRLGWVANVALIANMVCLFGLLALIPGAVLTLPGIAGLVLTV 503
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 506 GMAVDTNVIIFERIKEERRQGSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFCGV 585
Cdd:PRK12933 504 GMAVDTNVLIFERIKDKLKEGRSFAQAIDTGFDSAFSTIFDANFTTMITAVVLYSIGNGPIQGFALTLGLGLLTSMFTGI 583
|
570
....*....|.
gi 908740498 586 VVSGQLSQWFY 596
Cdd:PRK12933 584 FASRALINLVY 594
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
113-599 |
2.84e-168 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 487.04 E-value: 2.84e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 113 ATAPYWLQRLGLSPIKLGLDLNGGVLFVLKVDTDKALEKRMENIALEaksqrIRDKLKGVRIERSSVAgLELVALPQGAA 192
Cdd:PRK05812 27 PATPEWLPALGAKPMKLGLDLRGGVHFLLEVDMDDALKKRLESLADD-----LRSLLREKKIRYGGVE-ITFRDAEDRDK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 193 ALqqlqttllaqfqhlsvqthkhgNLLRATLSYDEAGKAAFEKQTMTQALTTLRSRIEELGITEAVTQRQGANYIRIELP 272
Cdd:PRK05812 101 AI----------------------ALLRKLSSLTEAELKEITEEALEQAIEIIRNRVNELGVAEPVIQRQGADRIVVELP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 273 GVQDPAAAKRIIGATAQLSFHALQefggkrvkaehgivgldplAIFTGADIDSAQAGRDEYGKPLVQLFLSSRGGDKMLR 352
Cdd:PRK05812 159 GVQDTARAKEILGKTATLEFRLVP-------------------VILTGDDITDASASFDQQGQPVVNITLDSEGAKKFAD 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 353 FSRANVGEPMATMYSEyiadsrgdirqssQVISVATIQQVL-GQRFSITNLGSWQKAQDLALLLRAGSLDAPLTIVTERT 431
Cdd:PRK05812 220 ITKANIGKRMAIVLDG-------------EVISAPVIQSAItGGSAQITGNFTAEEARDLALLLRAGALPAPLEIVEERT 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 432 IGPNLGAQNIASGFGALALGLSLTLGFMLLWYRKLGVIACMALVANLVCLVGLMSLLpGVVLTLPGIAGLVLTIGMAVDT 511
Cdd:PRK05812 287 IGPSLGADSIRAGLIAGLIGLALVLLFMILYYRLFGLIANIALVANLVLILAVLSLL-GATLTLPGIAGIVLTIGMAVDA 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 512 NVIIFERIKEERRQGSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFCGVVVSGQL 591
Cdd:PRK05812 366 NVLIFERIREELREGRSLRSAIEAGFKRAFSTILDSNITTLIAAIILYALGTGPVKGFAVTLGIGILTSMFTAITVTRAL 445
|
....*...
gi 908740498 592 SQWFYRTK 599
Cdd:PRK05812 446 VNLLYGRR 453
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
125-602 |
1.92e-148 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 435.31 E-value: 1.92e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 125 SPIKLGLDLNGGVLFVLKVDTDKALEKrmenialeaksqrirdklkgvrierssvaglelvalpqgaaalqqlqttllaq 204
Cdd:COG0342 29 KPIKLGLDLQGGVHLLLEVDTDAALDE----------------------------------------------------- 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 205 fqhlsvqthkhgnllratlsyDEAGKAAFEKQTMTQALTTLRSRIEELGITEAVTQRQGANYIRIELPGVQDPAAAKRII 284
Cdd:COG0342 56 ---------------------DGDGIREVTEEALDQAIEILRNRVNELGVSEPVIQRQGDDRIVVELPGVQDPAEAKELL 114
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 285 GATAQLSFHALQE---------FGGKRVKAEHGI-VGLDPLAIFTGADIDSAQAGRD-EYGKPLVQLFLSSRGGDKMLRF 353
Cdd:COG0342 115 GKTAKLEFRLVDDsadaqaavpAGSELLPCRDGQpYLLLGPVVLTGDDLTDASAGFDqQTGQPVVSFTLDSEGAKKFADA 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 354 SRANVGEPMATMYSEyiadsrgdirqssQVISVATIQQVL-GQRFSITNLGSWQKAQDLALLLRAGSLDAPLTIVTERTI 432
Cdd:COG0342 195 TRENVGKPLAIVLDG-------------EVISAPVIQEPItGGSAQITGSFTVEEAQDLALLLRAGALPAPLEIVEERTV 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 433 GPNLGAQNIASGFGALALGLSLTLGFMLLWYRKLGVIACMALVANLVCLVGLMSLLpGVVLTLPGIAGLVLTIGMAVDTN 512
Cdd:COG0342 262 GPTLGADSIEKGLIAGLIGLLLVALFMLLYYRLPGLVANIALALNVVLLLGVLSLL-GATLTLPGIAGIILTIGMAVDAN 340
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 513 VIIFERIKEERRQGSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFCGVVVSGQLS 592
Cdd:COG0342 341 VLIFERIREELRAGRSLRAAIEAGFKRAFSTILDANVTTLIAAVVLFVLGTGPVKGFAVTLILGILISMFTAVPVTRPLL 420
|
490
....*....|
gi 908740498 593 QWFYRTKSAK 602
Cdd:COG0342 421 NLLLGRRRLK 430
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
222-588 |
6.10e-121 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 363.53 E-value: 6.10e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 222 TLSYDEAGKAAFEKQTMTQALTTLRSRIEELGITEAVTQRQGANYIRIELPGVQDPAAAKRIIGATAQLSFH-------- 293
Cdd:TIGR01129 22 VLKLSEAEVNAIRKDALEQVITILRNRVNALGVSEPVVQRQGKDRIVVELPGVTDTSRAKDILGGTATLEFRlvddests 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 294 ------ALQEFGGKRVKA---EHGIVGLDPLAIFTGADIDSAQAGRDEY-GKPLVQLFLSSRGGDKMLRFSRANVGEPMA 363
Cdd:TIGR01129 102 pddalaGNVPAGSELLDSrsgDPKYYLLKKSPVLTGDHITDATSSVDQRsGQPVVSFSLDSEGARIFGDFTQANIGKRLA 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 364 TMYSEyiadsrgdirqssQVISVATIQQVL-GQRFSITNLGSWQKAQDLALLLRAGSLDAPLTIVTERTIGPNLGAQNIA 442
Cdd:TIGR01129 182 IVLDN-------------KVVSAPTIQEAItGGSGQITGNFTAEEANDLALVLRSGALPAPLQILEERTIGPSLGADSIE 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 443 SGFGALALGLSLTLGFMLLWYRKLGVIACMALVANLVCLVGLMSLLpGVVLTLPGIAGLVLTIGMAVDTNVIIFERIKEE 522
Cdd:TIGR01129 249 AGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILSAF-GATLTLPGIAGLILTIGMAVDANVLIYERIKEE 327
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 908740498 523 RRQGSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFCGVVVS 588
Cdd:TIGR01129 328 LRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLFTALVFT 393
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
239-602 |
3.64e-110 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 347.22 E-value: 3.64e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 239 TQALTTLRSRIEELGITEAVTQRQGANYIRIELPGVQDPAAAKRIIGATAQLSFHALQEF--GGKRVKAEHGIVGLDPLA 316
Cdd:PRK13024 62 DSTVEVLRNRIDGLGVSEPNIQREGNNRIRVELPGVQDPERARELLGSTAKLTFRDVTDPppPGVGGPVVGPDEGKDTAV 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 317 I----FTGADIDSAQAGRDEY--GKPLVQLFLSSRGGDKMLRFSRANV-----GEPMAtmyseyiadsrgdIRQSSQVIS 385
Cdd:PRK13024 142 LnpvlLSGDDLTDAGAKFDQDqtNRPSVSLKLKSEGAKKWAKVTEKNSkkgppNNRIA-------------IVLDPKVIS 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 386 VATIQQVL-GQRFSITNLGSWQKAQDLALLLRAGSLDAPLTIVTERTIGPNLGAQNIASGFGALALGLSLTLGFMLLWYR 464
Cdd:PRK13024 209 APTVNQPInGGSVQISGNFTVEEAKDLANLLNAGALPAPLKIIESRSVGPTLGQDAIDAGIIAGIIGFALIFLFMLVYYG 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 465 KLGVIACMALVANLVCLVGLMSLLpGVVLTLPGIAGLVLTIGMAVDTNVIIFERIKEERRQGSSMRAALQRGYQQAQSSI 544
Cdd:PRK13024 289 LPGLIANIALLLYIFLTLGALSSL-GAVLTLPGIAGLVLGIGMAVDANVLIFERIKEELRKGKSLKKAFKKGFKNAFSTI 367
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 908740498 545 IDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFCGVVVSGQLSQWFYRTKSAK 602
Cdd:PRK13024 368 LDSNITTLIAAAILFFFGTGPVKGFATTLIIGILASLFTAVFLTRLLLELLVKRGDKK 425
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
113-602 |
7.65e-89 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 293.55 E-value: 7.65e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 113 ATAPYWLQRlglSPIKLGLDLNGGVLFVLKVDTDKALEKRMENIALEaksqrIRDKLKGVRIERSSVAG------LELVA 186
Cdd:PRK14726 34 ASLPSWLPH---RQVTLGLDLQGGSHIVLKVERSDIVKDRLEETVAN-----IRNALRDAGIRYTGLTGngqtvqVRITD 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 187 LPQGAAALQQLQTTLLA---------QFQHLSVQTHKHGnLLRATLSydEAGKAAFEKQTMTQALTTLRSRIEELGITEA 257
Cdd:PRK14726 106 PAQTQAAVDALKPLTAPvsagglggsSIQELTLQEGGEG-QLRLQLT--DAGIDYRVSSALTQSIEVVRRRVAELGTTEP 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 258 VTQRQGANYIRIELPGVQDPAAAKRIIGATAQLSFHAL-------QEFGGKRVKAEHGIVGLD--PL-------AIFTGA 321
Cdd:PRK14726 183 LIRRQGDDRIVVQVPGLVDPQRLKNLLNQPAKLSFRLVdssmpaqEALNGRPPATSEVLYSLDdpPVpylverrAFVSGE 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 322 DIDSAQAGRD-EYGKPLVQLFLSSRGGDKMLRFSRANVGEPMAtmyseyiadsrgdIRQSSQVISVATIQQ-VLGQRFSI 399
Cdd:PRK14726 263 NLVDAQPVFDpQTNEPVVTFRLDAEGTQRFAQATQQNVGKHFA-------------IVLDGQVISAPVIDEaITGGEGRI 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 400 TNLGSWQKAQDLALLLRAGSLDAPLTIVTERTIGPNLGAQNIASGFGALALGLSLTLGFMLLWYRKLGVIACMALVANLV 479
Cdd:PRK14726 330 SGNFSEQGANDLAVLLRAGALPATLTVVEERTVGPGLGADSIAAGLVAGLIAAILVAALMIGFYGFLGVIAVIALIVNVV 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 480 CLVGLMSLLpGVVLTLPGIAGLVLTIGMAVDTNVIIFERIKEERRQGSSMRAALQRGYQQAQSSIIDANLTTMITALVLM 559
Cdd:PRK14726 410 LIIAVLSLL-GATLTLPGIAGIVLTIGMAVDSNVLIYERIREEEKTGHSLIQALDRGFSRALATIVDANVTILIAAVILF 488
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 908740498 560 SIGYGPVKGFAITLALGIITSMFCGVVVSGQLSQWFYRTKSAK 602
Cdd:PRK14726 489 FLGSGAVRGFAVTLAVGILTTVFTAFTLTRSLVAVWLRRRRPK 531
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
220-602 |
1.20e-48 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 181.35 E-value: 1.20e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 220 RATLSYDEAGKAAFEKQTmtqalTTLRSRIEELGITEAVTQRQGANYIRIELPGVQDPAAAKRIIGATAQLSFHALQEfg 299
Cdd:PRK13023 56 RLILQVQNAGKTDLETTA-----NIMRQRLEELGYGNPVVEGEGRNQIRVEVPGLYDAQLLKDILTIRGNLSFRAMDD-- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 300 gkRVKAEHGIVGLDPL--------------------AIFTGADIDSAQAG-RDEYGKPLVQLFLSSRGGDKMLRFSRANV 358
Cdd:PRK13023 129 --TMSPDDAIRGTPPAdseivysfddppvgyllkktPILTGHDITDAKASiSADDGQPVITLTLDDNGRRRLADLTAQGN 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 359 GEPMAtmyseyiadsrgdIRQSSQVISVATIQQVLG-QRFSITNLGSWQKAQDLALLLRAGSLDAPLTIVTERTIGPNLG 437
Cdd:PRK13023 207 ENSFA-------------IVVDNQVVSAPTVSGPLDtSELQIEGAFDLQAANNMAVVLRSGALPQAVTVLEERTIASALG 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 438 aQNIASGFGALALGLSLTLG-FMLLWYRKLGVIACMALVANLVCLVGLMSLLpGVVLTLPGIAGLVLTIGMAVDTNVIIF 516
Cdd:PRK13023 274 -EDYASAAVLAALLAALVVGlFMVLSYGILGVIALVALVVNIIILTAVLSLI-GASISLASIAGLVLTIGLAVDAHILIY 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 517 ERIKEERRQGSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFCGVVVSGQLSQWFY 596
Cdd:PRK13023 352 ERVREDRRKGYSVVQAMESGFYRALSTIVDANLTTLIAALVLFLLGSGTVHGFALTVAIGIGTTLFTTLTFTRLLIAQWV 431
|
....*.
gi 908740498 597 RTKSAK 602
Cdd:PRK13023 432 RTAKPK 437
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
430-582 |
4.14e-46 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 160.89 E-value: 4.14e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 430 RTIGPNLGAQNIASGFGALALGLSLTLGFMLLWYRKLGVIACMALVANLVCL-VGLMSLLpGVVLTLPGIAGLVLTIGMA 508
Cdd:TIGR00916 35 GTVGPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDVILiLGVLSLF-GATLTLPGIAGLLTIIGYS 113
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 908740498 509 VDTNVIIFERIKEERRQ--GSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMF 582
Cdd:TIGR00916 114 VDDTVVIFDRIREELRKykGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTY 189
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
383-582 |
3.73e-37 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 148.47 E-value: 3.73e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 383 VISVATIQQVLGQRFSITNLGSWQKAQDLALLLRAGSLDAPLTIVTERTIGPNLGAQNIASGFGALALGLSLTLGFMLLW 462
Cdd:PRK12911 850 VVSDPVLNVPLKDHASVSGKFSHREVHRLATDLKSGAMSFVPEVLSEEVISPELGKSQRTQGIISVCLGLAVLIVLMSVY 929
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 463 YRKLGVIACMALVANLVCLVGLMSLLPGVvLTLPGIAGLVLTIGMAVDTNVIIFERIKEERRQGSSMRAALQRGYQQAQS 542
Cdd:PRK12911 930 YRFGGVIASGAVLLNLLLIWAALQYLDAP-LTLSGLAGIVLAMGMAVDANVLVFERIREEYLLSRSLSESVEAGYKKAFS 1008
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 908740498 543 SIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMF 582
Cdd:PRK12911 1009 AIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMF 1048
|
|
| secD |
PRK08343 |
preprotein translocase subunit SecD; Reviewed |
235-588 |
4.04e-23 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 236245 [Multi-domain] Cd Length: 417 Bit Score: 102.26 E-value: 4.04e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 235 KQTMTQALTTLRSRIEELGITEAVTQRQGANYIRIELPGVqDPAAAKRIIGATaqlsfhalqefgGKrVKAEHGIVGLDP 314
Cdd:PRK08343 62 QETMDLVVEILESRLNALGLKDIKVYPVGDQYIVVEVPGV-DADTAKEIIEKQ------------GV-FEARIQTPGNNN 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 315 LAIFTGADIDSAQAGR--DEYGKPLVQLFLSSRGGDKMLR------FSRANVGEPMaTMY-----------SEYIADSrg 375
Cdd:PRK08343 128 ETVLTGDDIESVGSPSqdPSGGAWGVPFTLSEDGAEKFAEvakgkgATDDPSGHPL-DMYldgeliyaaplSPDLASG-- 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 376 dIRQSSQVISVAtiqqvlgqrFSITNLGSWQKAQDLALLLRAGSLDAPLTIVTERTIGPNLGAQ-----NIAsgfGALAL 450
Cdd:PRK08343 205 -LASGPVVITVG---------STGTTEEAKEEAKELYIHLRSGALPVKLDIEGSGSVSPSLGEQfkkgsLIA---GLLAL 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 451 glsLTLGFML-LWYRKLGVIACMAL--VANLVCLVGLMSLLpGVVLTLPGIAGLVLTIGMAVDTNVIIFERIKEERRQGS 527
Cdd:PRK08343 272 ---LAVALVVfLRYREPRIALPMVItsLSEVIIILGFAALI-GWQLDLASIAGIIAVIGTGVDDLIIITDEVLHEGKVPS 347
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 908740498 528 SMRaaLQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITsmfcGVVVS 588
Cdd:PRK08343 348 RKV--FLSRIKRAFFIIFAAAATTIAAMSPLAVMGLGDLKGFAITTILGVLI----GVLIT 402
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
435-603 |
7.44e-14 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 74.90 E-value: 7.44e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 435 NLGAQNIASGFGALALGLSLTLGFMLLWYR--KLGVIACMALVANLVCLVGLMSLLpGVVLTLPGIAGLVLTIGMAVDTN 512
Cdd:COG1033 598 AINESVIESQIRSLLLALLLIFLLLLLAFRslRLGLISLIPNLLPILLTFGLMGLL-GIPLNIATAVVASIALGIGVDYT 676
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 513 VIIFERIKEERRQGSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFCGVVVSGQLS 592
Cdd:COG1033 677 IHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLFSSFPPLADFGLLLALGLLVALLAALLLLPALL 756
|
170
....*....|.
gi 908740498 593 QWFYRTKSAKG 603
Cdd:COG1033 757 LLLDPRIAKKR 767
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
419-597 |
2.32e-13 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 68.79 E-value: 2.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 419 SLDAPLTIVTERTIGPNLGAQNIASGFGALA---LGLSLTLGFMLLWYRKLGVIAcmALVANLVCLVGLMSLLpGVVLTL 495
Cdd:pfam02355 8 NVGPDAEIISIETVGPTVGSELARKAVLALLfalLLILIYVGLRFEWRFALGAII--ALAHDVIITVGVFSLF-GIEVDL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 496 PGIAGLVLTIGMAVDTNVIIFERIKEERRQ--GSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITL 573
Cdd:pfam02355 85 ATVAALLTIIGYSVNDTVVVFDRVRENLRKktRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLAL 164
|
170 180
....*....|....*....|....
gi 908740498 574 ALGIITSMFCGVVVSGQLSQWFYR 597
Cdd:pfam02355 165 LVGVIVGTYSSIFIASPILLDLGE 188
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
445-587 |
3.79e-13 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 72.59 E-value: 3.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 445 FGALALGLslTLGFMLLWYRKL-GVIACMA-LVANLVCLVGLMSLLpGVVLTLPGIAGLVLTIGMAVDTNVIIFERIKEE 522
Cdd:COG1033 223 FFPLALLL--ILLLLFLFFRSLrGVLLPLLvVLLAVIWTLGLMGLL-GIPLSPLTILVPPLLLAIGIDYGIHLLNRYREE 299
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 908740498 523 RRQGSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFCGVVV 587
Cdd:COG1033 300 RRKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVLLAFLTSLTL 364
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
446-587 |
5.61e-13 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 72.12 E-value: 5.61e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 446 GALALGlslTLGFMLLWYRKLGVIACMALVANLVcLVGLMSLLPGVVLTLPGIAGLVLTIGMAVDTNVIIFERIKEERRQ 525
Cdd:NF037998 452 LILAIA---IMIYLLFAYRLLGLFAIIIALTSIS-LTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLYK 527
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 908740498 526 -GSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFCGVVV 587
Cdd:NF037998 528 nKRSIEESFKIANKETIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVIIV 590
|
|
| SecF |
COG0341 |
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ... |
375-578 |
2.14e-10 |
|
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440110 [Multi-domain] Cd Length: 291 Bit Score: 61.99 E-value: 2.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 375 GDIRQ--SSQVISVATIQQVLGQR-FSI-TNLGSWQKAQDLALLLRA-GSLDAPLTIVTERTIGPNLGAQNIASGFgaLA 449
Cdd:COG0341 61 EEVREalEEAGLGDASVQTFGSDNdVLIrTPPLDGESAEEVEKVRAAlKEAFGDVEIVRVEFVGPTVGKELTRKAL--LA 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 450 LGLSLTLGFMLLWYR---KLGVIACMALVANLVCLVGLMSLLpGVVLTLPGIAGLvLTI-GMAV-DTnVIIFERIKEERR 524
Cdd:COG0341 139 LLVALIGILIYIAFRfewRFAVGAVVALLHDVLITLGIFSLF-GLEFDLTFIAAL-LTIiGYSLnDT-VVVFDRIRENLR 215
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 908740498 525 QGSSMRAAlqrgyQQAQSSI-------IDANLTTMITALVLMSIGYGPVKGFAITLALGII 578
Cdd:COG0341 216 KYRKMTLA-----EIINLSInqtlsrtINTSLTTLLVVLALLFFGGETLRDFALALLIGII 271
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
425-579 |
2.33e-10 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 61.13 E-value: 2.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 425 TIVTERTIGPNLGAQNIASGfgALALGLSLTLGFMLLWYR---KLGVIACMALVANLVCLVGLMSLLpGVVLTLPGIAGL 501
Cdd:TIGR00966 81 EIRSIDAVGPSVGGELARKA--VLALLAALVLILIYITVRfewRFALGAIVALVHDVIITVGVYSLF-GIEVNLTTVAAL 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 502 VLTIGMAVDTNVIIFERIKEERRQGSSM--RAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIIT 579
Cdd:TIGR00966 158 LTIIGYSINDTVVVFDRIRENLRKYTRKtfTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVGVIV 237
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
423-582 |
1.15e-09 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 61.40 E-value: 1.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 423 PLTIVTERTIGPNLGAQNIASGFgaLALGLSLTLGFMLLWYR---KLGVIACMALVANLVCLVGLMSLLpGVVLTLPGIA 499
Cdd:PRK13024 558 GGTIPSSETVGPTVGKELARNAI--IAVLIALIGILLYILIRfewTFSLGAILALLHDVLIVIGFFSLF-RLEVDLTFIA 634
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 500 GLVLTIGMAVDTNVIIFERIKEERRQ--GSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGI 577
Cdd:PRK13024 635 AILTIIGYSINDTVVVFDRIRENLRLykKKDLREIVNKSINQTLSRTINTSLTTLLVLLALLIFGGSSLRNFSLALLVGL 714
|
....*
gi 908740498 578 ITSMF 582
Cdd:PRK13024 715 IVGTY 719
|
|
| secF |
PRK13021 |
preprotein translocase subunit SecF; Reviewed |
420-595 |
1.58e-08 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 237274 [Multi-domain] Cd Length: 297 Bit Score: 56.40 E-value: 1.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 420 LDAPLTIVTERTIGPNLGAQNIASGFGALALGLSLTLGFmlLWYR---KLGVIACMALVANLVCLVGLMSLLPgVVLTLP 496
Cdd:PRK13021 104 LGTEVQVLNSSIVGPQVGQELAEQGGLALLVAMLCILGY--LSYRfewRLASGALFALVHDVIFVLAFFALTQ-MEFNLT 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 497 GIAGLVLTIGMAVDTNVIIFERIKEERRQGSSMraALQRGYQQAQSSIIDANL----TTMITALVLMSIGYGPVKGFAIT 572
Cdd:PRK13021 181 VLAAVLAILGYSLNDSIIIADRIRELLIAKPKL--AIQEINNQAIVATFSRTMvtsgTTLMTVGALWIMGGGPLEGFSIA 258
|
170 180
....*....|....*....|...
gi 908740498 573 LALGIITSMFCGVVVSGQLSQWF 595
Cdd:PRK13021 259 MFIGILTGTFSSISVGTSLPELL 281
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
409-591 |
7.37e-07 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 52.31 E-value: 7.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 409 QDLALLLRaGSLDAPLTIVTERTIGPNLGAQniASGFGALALGLSLTLGFMLLWYR---KLGVIACMALVANLVCLVGlM 485
Cdd:PRK13023 546 QTVAVKLR-GEFEQDYSFQRVDVVGPTVSEQ--LSRAGVLAVILSLIGIFIYVWFRfrwQLALGAVLSTLHDVVILSG-M 621
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 486 SLLPGVVLTLPGIAGLVLTIGMAVDTNVIIFERIKEERR--QGSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGY 563
Cdd:PRK13023 622 FIVFRMEFNLWSVAAILTIIGYSLNDTVVIYDRVRENLRryKSAPLPAIIDASINQTLSRTLLTSFVTFLAHVPLYAFGG 701
|
170 180
....*....|....*....|....*...
gi 908740498 564 GPVKGFAITLALGIITSMFCGVVVSGQL 591
Cdd:PRK13023 702 SEIRMFALALSVGIIVASYSSIFIAAPL 729
|
|
| PRK08578 |
PRK08578 |
preprotein translocase subunit SecF; Reviewed |
423-558 |
1.22e-06 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 236302 [Multi-domain] Cd Length: 292 Bit Score: 50.31 E-value: 1.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 423 PLTIVTERTIGPNLGAQNIASGFGALA---LGLSLTLGFMllwYRK----LGVIAcmALVANLVCLVGLMSLLpGVVLTL 495
Cdd:PRK08578 115 SELNYSEKQIGPTFGSQFQEQALKAVGfafIGMAVVVFLI---FRTpvpsLAVIL--SAFSDIIIALALMNLF-GIELSL 188
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 908740498 496 PGIAGLVLTIGMAVDTNVIIFERIKeeRRQGS---SMRAALQRGyqqaqssiIDANLTTMITALVL 558
Cdd:PRK08578 189 ATVAALLMLIGYSVDSDILLTTRVL--KRRGTfdeSIKRAMRTG--------ITMTLTTIAAMAVL 244
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
429-602 |
2.46e-06 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 50.61 E-value: 2.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 429 ERTIGPNLGaqnIASGFGALALGLSLTLGFMLLWYRKLG-VIACMALVANLvclvGLMSLLpGVVLTLPGIAGLVLTIGM 507
Cdd:TIGR00921 188 EREFGKDMG---TTMAISGILVVLVLLLDFKRWWRPLLPlVIILFGVAWVL----GIMGWL-GIPLYATTLLAVPMLIGV 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 508 AVDTNVIIFERIKEERRQGSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFCGVVV 587
Cdd:TIGR00921 260 GIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLV 339
|
170
....*....|....*...
gi 908740498 588 S---GQLSQWFYRTKSAK 602
Cdd:TIGR00921 340 LpalLQSIDIGREKVKKE 357
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
439-578 |
3.38e-06 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 50.24 E-value: 3.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 439 QNIASGFGALALGLsLTLGFMLLW-YRKLGVIACMA-LVANLVCLVGLMSLLPGVVLTLPGIAGLVLTIGMAVDTNVIIF 516
Cdd:PRK12911 1235 QAVIALFGALGIIL-LYVSLRFEWrYAFSAICALIHdLLATCAVLVALHFFLQKIQIDLQAIGALMTVLGYSLNNTLIIF 1313
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 908740498 517 ERIKEERRQG--SSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGII 578
Cdd:PRK12911 1314 DRIREDRQEKlfTPMPILINDALQKTLGRTVMTTATTLSVLLILLFVGGGSIFNFAFIMTIGIL 1377
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
447-587 |
1.23e-05 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 48.22 E-value: 1.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 447 ALALGLSLTLGFMLLWYRKLgVIACMALVANLVCLV---GLMSLLpGVVLTLPGIA---GLVLTIGMAVDTNVIIFERIK 520
Cdd:COG2409 174 AELITLPVALVVLLLVFRSL-VAALLPLLTAGLAVGvalGLLALL-AAFTDVSSFApnlLTMLGLGVGIDYALFLVSRYR 251
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 908740498 521 EERRQGSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFCGVVV 587
Cdd:COG2409 252 EELRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVAVLAALTL 318
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
447-604 |
2.33e-05 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 47.54 E-value: 2.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 447 ALALGLSLTLGFMLLWYR----KLGVIACMALVANLVCLVGLMSLLpGVVLTLPGIAGLVLTIGMAVDTNVIIFERIKEE 522
Cdd:COG4258 642 LWLLLLALLLILLLLLLRlrslRRALRVLLPPLLAVLLTLAILGLL-GIPLNLFHLIALLLVLGIGIDYALFFTEGLLDK 720
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 523 RRQGSSMRaalqrgyqqaqsSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFcgvvvsgqLSQWFYRTKSAK 602
Cdd:COG4258 721 GELARTLL------------SILLAALTTLLGFGLLAFSSTPALRSFGLTVLLGILLALL--------LAPLLAPRRRPR 780
|
..
gi 908740498 603 GA 604
Cdd:COG4258 781 RA 782
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
447-582 |
3.66e-05 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 46.13 E-value: 3.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 447 ALALGLSLTLGFMLLWYRklGVIAcmALVANLVCLVGLMSLLpGVVLTLPGIAGL-----------VLTIGMAVDTNVII 515
Cdd:pfam03176 147 IEAVTLVVIFIILLIVYR--SVVA--ALLPLLTVGLSLGAAQ-GLVAILAHILGIglstfalnllvVLLIAVGTDYALFL 221
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 908740498 516 FERIKEERRQGSSMRAALQRGYQQAQSSIIDANLTTMIT--ALVLMSIGYgpVKGFAITLALGIITSMF 582
Cdd:pfam03176 222 VSRYREELRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAmlALSFARLPV--FAQVGPTIAIGVLVDVL 288
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
447-588 |
1.58e-04 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 44.99 E-value: 1.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 447 ALALGLSLTLGFMLLW--YRKLGVIAC--MALVANLVCLVGLMSLLPGVvLTLPGIAGLVLTIGMAVDTNVIIFERIKEE 522
Cdd:TIGR03480 272 TVAGLLSFVLVLVLLWlaLRSPRLVFAvlVTLIVGLILTAAFATLAVGH-LNLISVAFAVLFIGLGVDFAIQFSLRYREE 350
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 908740498 523 RRQGSSMRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYgpvKGFAitlALGII--TSMFCGVVVS 588
Cdd:TIGR03480 351 RFRGGNHREALSVAARRMGAALLLAALATAAGFFAFLPTDY---KGVS---ELGIIagTGMFIALFVT 412
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
450-587 |
2.15e-04 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 44.44 E-value: 2.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 450 LGLSLTLGFMLLWYRKL--GVIACMALVANLVCLVGLMSLLpGVVLTLPGIAGLVLTIGMAVDTNVIIFERIKEERRQGS 527
Cdd:TIGR00921 575 AGAILVLMILLAVFRNPikAVFPLIAIGSGILWAIGLMGLR-GIPSFLAMATTISIILGLGMDYSIHLAERYFEERKEHG 653
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 528 SmRAALQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFCGVVV 587
Cdd:TIGR00921 654 P-KEAITHTMERTGPGILFSGLTTAGGFLSLLLSHFPIMRNFGLVQGIGVLSSLTAALVV 712
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
439-587 |
2.30e-04 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 44.32 E-value: 2.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 439 QNIASGFGALALGLSLTLGFMLL------WYRKLGVIacMALVANLVC-LVGLMslLPGVVLTLPGIAGLVLTIGMAVDT 511
Cdd:COG0841 846 EQESFSSLGLAFLLALLLVYLVLaaqfesFIQPLIIL--LTVPLALIGaLLGLL--LTGTPLNIYSQIGLIMLIGIVVKN 921
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 512 NVIIFERIKEERRQGSSMRAAlqrgyqqaqssIIDANLT----------TMITALVLMSIGYGP----VKGFAITLALGI 577
Cdd:COG0841 922 AILLVDFANQLREEGMSLREA-----------ILEAARLrlrpilmtslATILGLLPLALGTGAgaefRQPLGIAVIGGL 990
|
170
....*....|
gi 908740498 578 ITSMFCGVVV 587
Cdd:COG0841 991 LFSTLLTLFV 1000
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
459-587 |
6.51e-04 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 43.03 E-value: 6.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 459 MLLWYRKL--GVIACMALVANLVCLVGLMSLLP---GVVLTLPGIAGLV-LTIGMAVDTNVIIFERIKEERRQGSSMRAA 532
Cdd:TIGR00833 190 LLLVYRSPitMLVPLVSVGFSVVVAQGIVSLLGipgLIGVNAQTTVLLTaLVIGAGTDYAVFLTGRYHEERRKGESLEEA 269
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 908740498 533 LQRGYQQAQSSIIDANLTTMITALVLMSIGYGPVKGFAITLALGIITSMFCGVVV 587
Cdd:TIGR00833 270 AAEALRGTGKAILGSALTVAVAFLALSLARLPSFKTLGVSCAVGVLVALLNAVTL 324
|
|
| PRK10629 |
PRK10629 |
EnvZ/OmpR regulon moderator MzrA; |
32-130 |
1.08e-03 |
|
EnvZ/OmpR regulon moderator MzrA;
Pssm-ID: 236728 Cd Length: 127 Bit Score: 39.22 E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 32 AMPNLYQNKTQLSISALPQAQTLPSPDTLVHLLQSHGFSVAQIG-SGEPTLVTLTSQTASASAQAVLAEAL-RDQATVKV 109
Cdd:PRK10629 27 AWSALRQQESTLAIRAVHQGASLPDGFYVYQHLDANGIHIKSITpENDSLLIRFDSPEQSAAAKEVLDRTLpHGYIIAQQ 106
|
90 100
....*....|....*....|.
gi 908740498 110 VEQATAPYWLQRLGLSPIKLG 130
Cdd:PRK10629 107 DDNSQAMQWLTRLRDNSHRLG 127
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
500-595 |
3.70e-03 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 40.36 E-value: 3.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 500 GLVLTIGMAVDTNVIIFERIKEE-RRQGSSMRAALQRGYQQAQSSIIdanLTTMITALVLMSIGY-GPVKG-----FAIT 572
Cdd:pfam00873 390 GLVLAIGLVVDDAIVVVENIERVlEENGLKPLEAAYKSMGEIGGALV---AIALVLSAVFLPILFlGGLTGrifrqFAIT 466
|
90 100
....*....|....*....|...
gi 908740498 573 LALGIITSMFCGVVVSGQLSQWF 595
Cdd:pfam00873 467 IVLAILLSVLVALTLTPALCATL 489
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
447-582 |
6.54e-03 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 39.70 E-value: 6.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 447 ALALGLSLTLGFMLLWYR--KLGVIACMALVanlVCLVG---LMSLLpGV---VLTLpgiAGLVLTIGMAVDTNVIIFER 518
Cdd:COG0841 336 TLLEAILLVVLVVFLFLRswRATLIPAVAIP---VSLIGtfaVMYLL-GFslnILTL---FALVLAIGIVVDDAIVVVEN 408
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908740498 519 IKEERRQGSSMRAALQRGYQQAQSSIIDANLTTMI--TALVLMSigyGPV----KGFAITLALGIITSMF 582
Cdd:COG0841 409 IERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAvfLPLAFMG---GITgqlfRQFALTVAIALLISLF 475
|
|
| |
