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Conserved domains on  [gi|914707079|ref|WP_050677713|]
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MULTISPECIES: peptidylprolyl isomerase [Exiguobacterium]

Protein Classification

peptidylprolyl isomerase PrsA family protein( domain architecture ID 1004913)

peptidylprolyl isomerase (PPIase) PrsA family protein may accelerate the folding of proteins; it catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

EC:  5.2.1.8
Gene Ontology:  GO:0003755
PubMed:  10228556

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
prsA super family cl32031
peptidylprolyl isomerase; Reviewed
 2-285 3.33e-49

peptidylprolyl isomerase; Reviewed


The actual alignment was detected with superfamily member PRK02998:

Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 165.14  E-value: 3.33e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079   2 KKKLLGAAAVASVFTLAACGSNDEaVINYKGGEVNKADVQEEAYEKAGAQIAFQQTMNKLLEKKYgkEVTDKEVEAEVKK 81
Cdd:PRK02998   4 KKLFLGTIISCVVLALSACGSSDN-VVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKY--KVSDEEAKKQVEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  82 TKDQFPDKeqFSTTLKSAGIKNEKEFEKVLRTQMLLTeaKSAKSKVTDKEIQerfDQEKVEVKASHILVAKESEAKDIKK 161
Cdd:PRK02998  81 AKDKMGDN--FKSTLEQVGLKNEDELKEKMKPEIAFE--KAIKATVTEKDVK---DNYKPEMKVSHILVKDEKTAKEVKE 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 162 QLDDGADFAKLAKEKSTDTGSGTKGGDLGYFTKGKMVKEFEDYAFKDGVeGKISDPIKTQFGYHIIKVVDRKEKKDFtlD 241
Cdd:PRK02998 154 KVNNGEDFAALAKQYSEDTGSKEQGGEISGFAPGQTVKEFEEAAYKLDA-GQVSEPVKTTYGYHIIKVTDKKELKPF--D 230

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 914707079 242 KEKSRIKKALAEEKAAQVNP---NDIYRSLMKEYDVKIENKDFKDAF 285
Cdd:PRK02998 231 EVKDSIRKDLEQQRLQDTTGkwkQQVVNDLLKDADIKVNDKEFKDTF 277
 
Name Accession Description Interval E-value
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 2-285 3.33e-49

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 165.14  E-value: 3.33e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079   2 KKKLLGAAAVASVFTLAACGSNDEaVINYKGGEVNKADVQEEAYEKAGAQIAFQQTMNKLLEKKYgkEVTDKEVEAEVKK 81
Cdd:PRK02998   4 KKLFLGTIISCVVLALSACGSSDN-VVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKY--KVSDEEAKKQVEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  82 TKDQFPDKeqFSTTLKSAGIKNEKEFEKVLRTQMLLTeaKSAKSKVTDKEIQerfDQEKVEVKASHILVAKESEAKDIKK 161
Cdd:PRK02998  81 AKDKMGDN--FKSTLEQVGLKNEDELKEKMKPEIAFE--KAIKATVTEKDVK---DNYKPEMKVSHILVKDEKTAKEVKE 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 162 QLDDGADFAKLAKEKSTDTGSGTKGGDLGYFTKGKMVKEFEDYAFKDGVeGKISDPIKTQFGYHIIKVVDRKEKKDFtlD 241
Cdd:PRK02998 154 KVNNGEDFAALAKQYSEDTGSKEQGGEISGFAPGQTVKEFEEAAYKLDA-GQVSEPVKTTYGYHIIKVTDKKELKPF--D 230

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 914707079 242 KEKSRIKKALAEEKAAQVNP---NDIYRSLMKEYDVKIENKDFKDAF 285
Cdd:PRK02998 231 EVKDSIRKDLEQQRLQDTTGkwkQQVVNDLLKDADIKVNDKEFKDTF 277
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 134-274 7.86e-40

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 136.24  E-value: 7.86e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 134 ERFDQEKvEVKASHILV---------AKESEAKDIKKQLDDGADFAKLAKEKSTDTGSGTKGGDLGYFTKGKMVKEFEDY 204
Cdd:COG0760    1 DQFDSPE-EVRASHILVkvppsedraKAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEA 79

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 205 AFKDGVeGKISDPIKTQFGYHIIKVVDRKEKKDFTLDKEKSRIKKALAEEKAaqvnpNDIYRSLMKEYDV 274
Cdd:COG0760   80 AFALKP-GEISGPVKTQFGYHIIKVEDRRPAETPPFEEVKQQIRQELFQQAL-----EAWLEELRKKAKI 143
Rotamase_3 pfam13616
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 138-233 6.05e-27

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 404499 [Multi-domain]  Cd Length: 116  Bit Score: 101.67  E-value: 6.05e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  138 QEKVEVKASHILVA-------KESEAK----DIKKQLDDGADFAKLAKEKSTDTGSGTKGGDLGYFTKGKMVKEFEDYAF 206
Cdd:pfam13616  11 SAPDSVKASHILISysqavsrTEEEAKakadSLLAALKNGADFAALAKTYSDDPASKNNGGDLGWFTKGQMVKEFEDAVF 90

                          90       100
                  ....*....|....*....|....*..
gi 914707079  207 KDGVeGKISDPIKTQFGYHIIKVVDRK 233
Cdd:pfam13616  91 SLKV-GEISGVVKTQFGFHIIKVTDKK 116
 
Name Accession Description Interval E-value
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 2-285 3.33e-49

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 165.14  E-value: 3.33e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079   2 KKKLLGAAAVASVFTLAACGSNDEaVINYKGGEVNKADVQEEAYEKAGAQIAFQQTMNKLLEKKYgkEVTDKEVEAEVKK 81
Cdd:PRK02998   4 KKLFLGTIISCVVLALSACGSSDN-VVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKY--KVSDEEAKKQVEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  82 TKDQFPDKeqFSTTLKSAGIKNEKEFEKVLRTQMLLTeaKSAKSKVTDKEIQerfDQEKVEVKASHILVAKESEAKDIKK 161
Cdd:PRK02998  81 AKDKMGDN--FKSTLEQVGLKNEDELKEKMKPEIAFE--KAIKATVTEKDVK---DNYKPEMKVSHILVKDEKTAKEVKE 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 162 QLDDGADFAKLAKEKSTDTGSGTKGGDLGYFTKGKMVKEFEDYAFKDGVeGKISDPIKTQFGYHIIKVVDRKEKKDFtlD 241
Cdd:PRK02998 154 KVNNGEDFAALAKQYSEDTGSKEQGGEISGFAPGQTVKEFEEAAYKLDA-GQVSEPVKTTYGYHIIKVTDKKELKPF--D 230

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 914707079 242 KEKSRIKKALAEEKAAQVNP---NDIYRSLMKEYDVKIENKDFKDAF 285
Cdd:PRK02998 231 EVKDSIRKDLEQQRLQDTTGkwkQQVVNDLLKDADIKVNDKEFKDTF 277
prsA PRK04405
peptidylprolyl isomerase; Provisional
 1-286 4.34e-49

peptidylprolyl isomerase; Provisional


Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 165.34  E-value: 4.34e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079   1 MKKKLLGAAAVASVFTLAACGSNDEAVINYKGGEVNkadvQEEAYEK-----AGAQIAFQQTMNKLLEKKYGKEVTDKEV 75
Cdd:PRK04405   5 MKKWALAAASAGLALSLAGCSSNQATVATYSGGKIT----QSQYYKEmkqssAGKTVLANMIIYRALEKQYGKKVSTKKV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  76 EAEVKKTKDQFpdKEQFSTTLKSAGIkNEKEFEKVLRTQMLLTEAKSAKSKVTDKEIQERFDQEKVEVKASHILVAKESE 155
Cdd:PRK04405  81 DKQYNSYKKQY--GSSFDSVLSQNGM-TTSSFKQNLRTNLLSEAALKKLKKVTNSQLKKAWKSYQPKVTVQHILVSKKST 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 156 AKDIKKQLDDGADFAKLAKEKSTDTGSGTKGGDLGYF--TKGKMVKEFEDYAFKDGVEGKISDPIKTQFGYHIIKVVDRK 233
Cdd:PRK04405 158 AETVIKKLKDGKDFAKLAKKYSTDTATKNKGGKLSAFdsTDTTLDSTFKTAAFKLKNGEYTTTPVKTTYGYEVIKMIKHP 237

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 914707079 234 EKKDFTldKEKSRIKKALAEEKAA-QVNPNDIYRSLMKEYDVKIENKDFKDAFD 286
Cdd:PRK04405 238 AKGTFS--DHKKALTKQIYAKWASdSSVMQRVISKVLKKANVSIKDKDLKDALS 289
prsA PRK03002
peptidylprolyl isomerase PrsA;
3-287 2.00e-48

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 163.18  E-value: 2.00e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079   3 KKLLGAAAVASVFTLAACGSNDE--AVINYKGGEVNKADVQEEAYEKAGAQIAFQQTMNKLLEKKYgkEVTDKEVEAEVK 80
Cdd:PRK03002   4 KHIFIITALISILMLSACGQKNSsaTVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKY--KVSDDDVDKEVQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  81 KTKDQFPDkeQFSTTLKSAGIKNEKEFEKVLRTQMLLTEAksAKSKVTDKEIQerfDQEKVEVKASHILVAKESEAKDIK 160
Cdd:PRK03002  82 KAKSQYGD--QFKNVLKNNGLKDEADFKNQIKFKLAMNEA--IKKSVTEKDVK---DHYKPEIKASHILVSDENEAKEIK 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 161 KQLDDGADFAKLAKEKSTDTGSGTKGGDLGYFTKGKMVKEFEDYAFKDGVeGKISDPIKTQFGYHIIKVVDRKEKKDFtl 240
Cdd:PRK03002 155 KKLDAGASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKV-GQISNPVKSPNGYHIIKLTDKKDLKPY-- 231

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 914707079 241 DKEKSRIKKALAEEKAA-QVNPNDIYRSLMKEYDVKIENKDFKDAFDL 287
Cdd:PRK03002 232 DEVKDSIRKNLEEERTAdPIFGKKLLQSELKKANIKINDSELEDTFTI 279
prsA PRK03095
peptidylprolyl isomerase PrsA;
1-289 2.16e-44

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 152.84  E-value: 2.16e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079   1 MKKKLLGAAAVaSVFTLAACG-SNDEAVINYKGGEVNKADVQEEAYEKAGAQIAFQQTMNKLLEKKYgkEVTDKEVEAEV 79
Cdd:PRK03095   1 MKKAMLALAAT-SVIALSACGtSSSDKIVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNY--KVEDKEVDKKY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  80 KKTKDQFPDkeQFSTTLKSAGIKnEKEFEKVLRTQmlLTEAKSAKSKVTDKEIQERFdqeKVEVKASHILVAKESEAKDI 159
Cdd:PRK03095  78 DEMKKQYGD--QFDTLLKQQGIK-EETLKTGVRAQ--LAQEKAIEKTITDKELKDNY---KPEIKASHILVKDEATAKKV 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 160 KKQLDDGADFAKLAKEKSTDTGSGTKGGDLGYFTKGKMVKEFEDYAFKDGvEGKISDPIKTQFGYHIIKVVDRKEkKDFT 239
Cdd:PRK03095 150 KEELGQGKSFEELAKQYSEDTGSKEKGGDLGFFGAGKMVKEFEDAAYKLK-KDEVSEPVKSQFGYHIIKVTDIKE-PEKS 227

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 914707079 240 LDKEKSRIKKALAEEKAAQVN-PNDIYRSLMKEYDVKIENKDFKDAFDLDK 289
Cdd:PRK03095 228 FEQSKADIKKELVQKKAQDGEfMNDLMMKEIKKADVKVDDKDLKDLFEEKK 278
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 134-274 7.86e-40

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 136.24  E-value: 7.86e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 134 ERFDQEKvEVKASHILV---------AKESEAKDIKKQLDDGADFAKLAKEKSTDTGSGTKGGDLGYFTKGKMVKEFEDY 204
Cdd:COG0760    1 DQFDSPE-EVRASHILVkvppsedraKAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEA 79

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 205 AFKDGVeGKISDPIKTQFGYHIIKVVDRKEKKDFTLDKEKSRIKKALAEEKAaqvnpNDIYRSLMKEYDV 274
Cdd:COG0760   80 AFALKP-GEISGPVKTQFGYHIIKVEDRRPAETPPFEEVKQQIRQELFQQAL-----EAWLEELRKKAKI 143
prsA PRK00059
peptidylprolyl isomerase; Provisional
 73-264 1.45e-32

peptidylprolyl isomerase; Provisional


Pssm-ID: 234605 [Multi-domain]  Cd Length: 336  Bit Score: 122.90  E-value: 1.45e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  73 KEVEAEVKKTKDQ-FPDKEQFSTTLKSAGIkNEKEFEKVLRTQMLLTEAKSAKSK---VTDKEIQERFDQEK-------V 141
Cdd:PRK00059 117 KEVDKKINEIKKQfNNDEEQFEEALKATGF-TEETFKEYLKNQIIIEKVINEVVKdvkVTDKDAQKYYNENKskftekpN 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 142 EVKASHILVAKESEAKDIKKQLDDGADFAKLAKEKSTDTGSGTKGGDLGY--FTKGKMVKEFEDyAFKDGVEGKISDPIK 219
Cdd:PRK00059 196 TMHLAHILVKTEDEAKKVKKRLDKGEDFAKVAKEVSQDPGSKDKGGDLGDvpYSDSGYDKEFMD-GAKALKEGEISAPVK 274

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 914707079 220 TQFGYHIIKVVDRKEKKDFTLDKEKSRIKKALAEEKAAQVNPNDI 264
Cdd:PRK00059 275 TQFGYHIIKAIKKKEYPVKPFDSVKEDIKKQLLQEKQSEVFKKKI 319
Rotamase_3 pfam13616
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 138-233 6.05e-27

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 404499 [Multi-domain]  Cd Length: 116  Bit Score: 101.67  E-value: 6.05e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  138 QEKVEVKASHILVA-------KESEAK----DIKKQLDDGADFAKLAKEKSTDTGSGTKGGDLGYFTKGKMVKEFEDYAF 206
Cdd:pfam13616  11 SAPDSVKASHILISysqavsrTEEEAKakadSLLAALKNGADFAALAKTYSDDPASKNNGGDLGWFTKGQMVKEFEDAVF 90

                          90       100
                  ....*....|....*....|....*..
gi 914707079  207 KDGVeGKISDPIKTQFGYHIIKVVDRK 233
Cdd:pfam13616  91 SLKV-GEISGVVKTQFGFHIIKVTDKK 116
prsA PRK01326
foldase protein PrsA; Reviewed
 1-285 5.05e-24

foldase protein PrsA; Reviewed


Pssm-ID: 179281 [Multi-domain]  Cd Length: 310  Bit Score: 99.12  E-value: 5.05e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079   1 MKKKLL-GAAAVASVFTLAACGSNDEA--VINYKGGEVNKADVQEEA-YEKAGAQIAFQQTMNKLLEKKYGKEVTDKEVE 76
Cdd:PRK01326   1 MKKKLIaGAVTLLSVATLAACSKTNENtkVISMKGDTITVSDFYNQVkNNPSAQQAMLNLTISRVFEKQYGDKVSDKEVE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  77 AEVKKTKDQFPDkeQFSTTLKSAGIKNEkEFEKVLRTQMLLTEA--KSAKSKVTDKEIQERFDQEKVEVKASHILVAKES 154
Cdd:PRK01326  81 KAYAKTAKQYGA--SFSRALAQAGLTPE-TYKAQIRTSKLVEYAvkEAAKKELTDEAYKKAYEEYTPEVTAQIIRLDNED 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 155 EAKDIKKQLD-DGADFAKLAKEKSTDTGSGTK-GGDLGYFTKGKMVKEFEDYAFKDGVEGKIS--DPIKTQFGYHIIKVV 230
Cdd:PRK01326 158 KAKSVLEEAKaEGADFAQIAKENTTTKEKKGEyKFDSGSTNVPEQVKKAAFALDEDGVSDVISvlDPTAYQSKYYIVKVT 237

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 914707079 231 DRKEKKDfTLDKEKSRIKKALAEEKAAQVN-PNDIYRSLMKEYDVKIENKDFKDAF 285
Cdd:PRK01326 238 KKTEKKS-DWKDYKKRLKAIILAQKQNDSNfQNKVIAKALDKANVKIKDKAFANIL 292
PRK10788 PRK10788
periplasmic folding chaperone; Provisional
 58-256 2.89e-21

periplasmic folding chaperone; Provisional


Pssm-ID: 182731 [Multi-domain]  Cd Length: 623  Bit Score: 93.92  E-value: 2.89e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  58 MNKLLEKKygkEVTDKEVEAEVKKTKDQFPDKEQFsttlKSAGIKnekefekvlrtqmLLTEAKSAKSKVTDKEIQERFD 137
Cdd:PRK10788 200 VNALAAKQ---TVTDEEIKSYYDQNKNNFMAPEQF----KVSYIK-------------LDAATMQQKITVSDADIQAYYD 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 138 QEKVE------VKASHILVAKESEAKDIKKQLDDGADFAKLAKEKSTDTGSGTKGGDLGYFTKGKMVKEFEDYAFKDgvE 211
Cdd:PRK10788 260 QHQDQftqperKRYSIIQTKTEAEAKAVLDELKKGADFATLAKEKSTDIISARNGGDLGWLEPATTPDELKNAGLKE--K 337

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 914707079 212 GKISDPIKTQFGYHIIKVVDRKEKKDFTLDKEKSRIKKALAEEKA 256
Cdd:PRK10788 338 GQLSGVIKSSVGFLIVRLDDIQPAKVKPLSEVRDDIAAKVKQEKA 382
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 153-231 4.99e-21

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 85.43  E-value: 4.99e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  153 ESEAKDIKKQLDDGAD-FAKLAKEKSTDTGSGTKGGDLGYFTKGKMVKEFEDYAFKDGVeGKISDPIKTQFGYHIIKVVD 231
Cdd:pfam00639  18 KAKAEEILEQLKSGEDsFAELARKYSDDCPSAANGGDLGWFTRGQLPPEFEKAAFALKP-GEISGPVETRFGFHIIKLTD 96
PRK15441 PRK15441
peptidyl-prolyl cis-trans isomerase C; Provisional
 145-233 6.94e-19

peptidyl-prolyl cis-trans isomerase C; Provisional


Pssm-ID: 185338 [Multi-domain]  Cd Length: 93  Bit Score: 79.68  E-value: 6.94e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 145 ASHILVAKESEAKDIKKQLDDGADFAKLAKEKSTdTGSGTKGGDLGYFTKGKMVKEFEDYAFKdGVEGKISDPIKTQFGY 224
Cdd:PRK15441   7 ALHILVKEEKLALDLLEQIKNGADFGKLAKKHSI-CPSGKRGGDLGEFRQGQMVPAFDKVVFS-CPVLEPTGPLHTQFGY 84


                 ....*....
gi 914707079 225 HIIKVVDRK 233
Cdd:PRK15441  85 HIIKVLYRN 93
PRK12450 PRK12450
foldase protein PrsA; Reviewed
 1-283 5.09e-18

foldase protein PrsA; Reviewed


Pssm-ID: 138982 [Multi-domain]  Cd Length: 309  Bit Score: 82.44  E-value: 5.09e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079   1 MKKKLLGAAAVASVFTLAACGS--NDEAVINYKGGEVNKADVQEEAYEKAGAQIA-FQQTMNKLLEKKYGKEVTDKEVEA 77
Cdd:PRK12450   4 MNKLITGVVTLATVVTLSACQSshNNTKLVSMKGDTITVSDFYNETKNTELAQKAmLSLVISRVFETQYANKVSDKEVEK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  78 EVKKTKDQFpdKEQFSTTLKSAGIKNEKeFEKVLRTQMLLTEA---KSAKSKVTDKEIQERFDQEKVEVKASHILVAKES 154
Cdd:PRK12450  84 AYKQTADQY--GTSFKTVLAQSGLTPET-YKKQIRLTKLVEYAvkeQAKNETISKKDYRQAYDAYTPTMTAEIMQFEKEE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 155 EAKDIKKQLD-DGADFAKLAKEKSTDTGSGTKGGdlgyFTKGKMVKEFEDYAFKDGV-EGKIS------DPIKTQFGYHI 226
Cdd:PRK12450 161 DAKAALEAVKaEGADFAAIAKEKTIAADKKTTYT----FDSGETTLPAEVVRAASGLkEGNRSeiitalDPATSKRTYHI 236

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 914707079 227 IKVVDRKEKKDfTLDKEKSRIKKALAEEKAAQVN-PNDIYRSLMKEYDVKIENKDFKD 283
Cdd:PRK12450 237 IKVTKKATKKA-DWKAYQKRLKDIIVTGKLKDPDfQNKVIAKALDKANVKIKDKAFAN 293
PTZ00356 PTZ00356
peptidyl-prolyl cis-trans isomerase (PPIase); Provisional
 153-228 1.76e-14

peptidyl-prolyl cis-trans isomerase (PPIase); Provisional


Pssm-ID: 185573 [Multi-domain]  Cd Length: 115  Bit Score: 68.51  E-value: 1.76e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 914707079 153 ESEAKDIKKQLDDGA-DFAKLAKEKStDTGSGTKGGDLGYFTKGKMVKEFEDYAFKDGVeGKISDPIKTQFGYHIIK 228
Cdd:PTZ00356  38 IKELAKWREQIVSGEkTFEEIARQRS-DCGSAAKGGDLGFFGRGQMQKPFEDAAFALKV-GEISDIVHTDSGVHIIL 112
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 142-258 6.16e-11

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 62.45  E-value: 6.16e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 142 EVKASHIL-----VAKESEAK----DIKKQLDDG-ADFAKLAKEKSTDTGSGTKGGDLGYFTkgkmvKEFEDYAFKDGV- 210
Cdd:PRK10770 266 EVHARHILlkpspIMTDEQARakleQIAADIKSGkTTFAAAAKEFSQDPGSANQGGDLGWAT-----PDIFDPAFRDALm 340

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 914707079 211 ---EGKISDPIKTQFGYHIIKVVDRKeKKDFTLDKEKSRIKKALAEEKAAQ 258
Cdd:PRK10770 341 rlnKGQISAPVHSSFGWHLIELLDTR-QVDKTDAAQKDRAYRMLFNRKFSE 390
Rotamase_2 pfam13145
PPIC-type PPIASE domain;
127-244 9.53e-08

PPIC-type PPIASE domain;


Pssm-ID: 432992 [Multi-domain]  Cd Length: 121  Bit Score: 49.75  E-value: 9.53e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  127 VTDKEIQERFDQEK-----VEVKASHILVAKESEAKDIKKQLDDGADFAKLAKEKStdtGSGTKGGDLGYFTKGKMV-KE 200
Cdd:pfam13145   1 VTEEELKAYYEENKdefstPEGRLLEILVFKDQVAADAALALLKAGALEDFAALAK---GEGIKAATLDIVESAELLpEE 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 914707079  201 FEDYAFKDGVeGKISDPIKTQFGYHIIKVVDRKEKKDFTLDKEK 244
Cdd:pfam13145  78 LAKAAFALKP-GEVSGPIKTGNGYYVVRVTEIKPAQPLPFEEAK 120
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 64-233 1.83e-07

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 52.05  E-value: 1.83e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079  64 KKYGKEVTDKEVE---AEVKKTKDQFPDkeQFSTTLKSAGIkNEKEFEKVLRTQMLLTEAKS--AKSKVT---------D 129
Cdd:PRK10770  67 QKMGVKISDEQLDqaiANIAAQNNMTLD--QMRSRLAYDGL-NYNTYRNQIRKEMIISEVRNneVRRRITilpqevdslA 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079 130 KEIQERFDQEKvEVKASHILVA------------KESEAKDIKKQLDDGADFAKLAKEKSTDTgSGTKGGDLGYFTKGKM 197
Cdd:PRK10770 144 KQIGNQNDAST-ELNLSHILIPlpenptqdqvdeAESQARSIVDQARNGADFGKLAIAYSADQ-QALKGGQMGWGRIQEL 221

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 914707079 198 VKEFEDyAFKDGVEGKISDPIKTQFGYHIIKVVDRK 233
Cdd:PRK10770 222 PGLFAQ-ALSTAKKGDIVGPIRSGVGFHILKVNDLR 256
SurA_N_3 pfam13624
SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a ...
 41-117 3.15e-04

SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a helical domain of unknown function. The C-terminus of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.


Pssm-ID: 433358 [Multi-domain]  Cd Length: 162  Bit Score: 40.63  E-value: 3.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914707079   41 QEEAYEKAGAQIAFQQTMN-KLLE---KKYGKEVTDKEVEAEVKKTK-----DQFpDKEQFSTTLKSAGIKnEKEFEKVL 111
Cdd:pfam13624  75 AELLDELGLRQQVLDQLIDrALLLqeaKKLGLAVSDEEVRQAIASIPafqedGKF-DKERYRQLLRANGLT-PAEFEASL 152


                  ....*.
gi 914707079  112 RTQMLL 117
Cdd:pfam13624 153 RQDLLL 158
YifL COG5567
Small periplasmic lipoprotein YifL (function unknown) [Function unknown];
1-21 8.05e-03

Small periplasmic lipoprotein YifL (function unknown) [Function unknown];


Pssm-ID: 444309  Cd Length: 43  Bit Score: 33.73  E-value: 8.05e-03
                         10        20
                 ....*....|....*....|.
gi 914707079   1 MKKKLLGAAAVASVFTLAACG 21
Cdd:COG5567    1 MKKLLRLLLLLLLLFTLAGCG 21
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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