|
Name |
Accession |
Description |
Interval |
E-value |
| NIT |
pfam08376 |
Nitrate and nitrite sensing; The nitrate- and nitrite sensing domain (NIT) is found in ... |
107-343 |
4.95e-29 |
|
Nitrate and nitrite sensing; The nitrate- and nitrite sensing domain (NIT) is found in receptor components of signal transducing pathways in bacteria which control gene expression, cellular motility and enzyme activity in response to nitrate and nitrite concentrations. The NIT domain is predicted to be all alpha-helical in structure.
Pssm-ID: 462453 [Multi-domain] Cd Length: 227 Bit Score: 116.05 E-value: 4.95e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 107 VHDLQRERALAVIRVSSNDPLRQTG-LDAQIAKVDHDVDELRNAAVNLDSTDQAAsDRYAHGLQRLDALRPLREAMANG- 184
Cdd:pfam08376 1 VHALQKERGLSAGYLASGGGGRFAAeLAAQRAATDAALAALRAALAELALPARLA-DRLAALLRALDQLPALRRQVDAGa 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 185 YSDRAILDTYSSVLDALIQLGREVTTATTDRDLLRVGNSTQAISEAKEYILRGDSALQIAAFRNDFPGNLLDETRAAEAS 264
Cdd:pfam08376 80 LSALEALAAYTELIAALLDLVDELAAGSPDPELARQLRALAALLRAKEAAGQERALLAAALAAGRFTAAEYRRFLSLVAA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 916484329 265 GDAQISAFLTNATPDQVQLYNDTYSGPEVDERRRLQTQAfasaqqnkplnIEPTGLGQDSAVAADKLRAVEASLLSQMR 343
Cdd:pfam08376 160 QRAALAEFRAAATPEQRALYDATVTGPAVAAAERLRDRL-----------VDAAAWFAASTARIDLLREVEDRLADDLA 227
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
480-674 |
1.88e-25 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 106.14 E-value: 1.88e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 480 LGVIDRLEADEQ--DPDHLASLFELDHLATRLRRNGESLLVLSG--AGLAKSVPKPVPAADVIGAAVSEIEQYA-----R 550
Cdd:COG2205 35 LGAAELLLDEEDlsPEERRELLEIIRESAERLLRLIEDLLDLSRleSGKLSLELEPVDLAELLEEAVEELRPLAeekgiR 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 551 IEIGIVPEVAVQGLAIHDLVHVLAELLDNATYFSEPETKITVRAVITRKKALaIQVTDHGVGMSEERLAEVNERLADPPD 630
Cdd:COG2205 115 LELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARREGDGVR-ISVSDNGPGIPEEELERIFERFYRGDN 193
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 916484329 631 LDVSVTRRMGLYVVARLAQRHGIEVRLRENEDieGGVIARVVVP 674
Cdd:COG2205 194 SRGEGGTGLGLAIVKRIVEAHGGTIWVESEPG--GGTTFTVTLP 235
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
568-676 |
3.34e-16 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 75.48 E-value: 3.34e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 568 DLVHVLAELLDNATYFSEPETKITVRavITRKKALAIQVTDHGVGMSEERLAEVNERLADPPDLDVSVTrRMGLYVVARL 647
Cdd:pfam02518 5 RLRQVLSNLLDNALKHAAKAGEITVT--LSEGGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRGGGGT-GLGLSIVRKL 81
|
90 100
....*....|....*....|....*....
gi 916484329 648 AQRHGIEVRLRENEDieGGVIARVVVPME 676
Cdd:pfam02518 82 VELLGGTITVESEPG--GGTTVTLTLPLA 108
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
569-676 |
2.19e-15 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 73.07 E-value: 2.19e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 569 LVHVLAELLDNATYFSEPETKITVRaVITRKKALAIQVTDHGVGMSEERLAEVNERLADPPDLDVSVTRR-MGLYVVARL 647
Cdd:smart00387 6 LRQVLSNLLDNAIKYTPEGGRITVT-LERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRKIGGTgLGLSIVKKL 84
|
90 100
....*....|....*....|....*....
gi 916484329 648 AQRHGIEVRLRENEDieGGVIARVVVPME 676
Cdd:smart00387 85 VELHGGEISVESEPG--GGTTFTITLPLE 111
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
489-671 |
3.05e-09 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 60.43 E-value: 3.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 489 DEQDPDHlaSLFELDHLATRLRRNGESLLVLS----GAGLAKSVPkpVPAADVIGAAVSEI---EQYARIEIGI---VPE 558
Cdd:PRK10337 268 DPQARKK--ALLQLHAGIDRATRLVDQLLTLSrldsLDNLQDVAE--IPLEDLLQSAVMDIyhtAQQAGIDVRLtlnAHP 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 559 VAVQGLAIhdLVHVLAE-LLDNATYFSEPETKITVRAvitrkKALAIQVTDHGVGMSEERLAEVNERLADPPDLDVSVTr 637
Cdd:PRK10337 344 VIRTGQPL--LLSLLVRnLLDNAIRYSPQGSVVDVTL-----NARNFTVRDNGPGVTPEALARIGERFYRPPGQEATGS- 415
|
170 180 190
....*....|....*....|....*....|....
gi 916484329 638 RMGLYVVARLAQRHGIEVRLRENEdiEGGVIARV 671
Cdd:PRK10337 416 GLGLSIVRRIAKLHGMNVSFGNAP--EGGFEAKV 447
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
559-661 |
6.35e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 46.25 E-value: 6.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 559 VAVQGLAIHdLVHVLAELLDNATYFSEPETKITVRavITRKKALAIQVTDHGVGMSEERLAEVNERLADPPDLDVSVTRr 638
Cdd:cd16940 5 IQVQGDALL-LFLLLRNLVDNAVRYSPQGSRVEIK--LSADDGAVIRVEDNGPGIDEEELEALFERFYRSDGQNYGGSG- 80
|
90 100
....*....|....*....|...
gi 916484329 639 MGLYVVARLAQRHGIEVRLRENE 661
Cdd:cd16940 81 LGLSIVKRIVELHGGQIFLGNAQ 103
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
198-652 |
1.45e-05 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 49.01 E-value: 1.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 198 LDALIQLGREVTTATTDRDLLRVGNSTQAISEAKEYILRGDSALQIAAFRNDFPGNLLDETRAAEASGDAQISAFLTNAT 277
Cdd:COG4251 9 LLLLLLLLLLLLLLLLLLVLLLALALLLLLALLVLLLLLIRLLLLLLLSLLALLLLLLLLLLLLLVLAALALLLLLLLLE 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 278 PDQVQLYNDTYSGPEVDERRRLQTQAFASAQQNKPLNIEPTGLGQDSAVAADKLRAVEASLLSQMRAQADSLASNAVRSA 357
Cdd:COG4251 89 LALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALIL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 358 WVAGVVVLAALIAALMLMLVIARLMLRPLRVLRKTALDVAYTRLPETVQAILDDPDPVNASKKAVAPVPVDSRDEIGEVA 437
Cdd:COG4251 169 ALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLL 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 438 RSFDVVHEQAVKMAAEQALLRENVngifVNLSRRSQRL-----------------VERQLGVIDRLEADEQDPDHLASLF 500
Cdd:COG4251 249 ILVLELLELRLELEELEEELEERT----AELERSNEELeqfayvashdlreplrkISGFSQLLEEDYGDKLDEEGREYLE 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 501 ELDHLATRLRRNGESLLVLSGAGLAKSVPKPVPAADVIGAAVSEIEQY-----ARIEIGIVPEVavQGLAIHdLVHVLAE 575
Cdd:COG4251 325 RIRDAAERMQALIDDLLAYSRVGRQELEFEPVDLNELLEEVLEDLEPRieergAEIEVGPLPTV--RGDPTL-LRQVFQN 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 576 LLDNATYFSEPET--KITVRAVItRKKALAIQVTDHGVGMSE---ERLAEVNERLadppdldvsVTRR------MGLYVV 644
Cdd:COG4251 402 LISNAIKYSRPGEppRIEIGAER-EGGEWVFSVRDNGIGIDPeyaEKIFEIFQRL---------HSRDeyegtgIGLAIV 471
|
....*...
gi 916484329 645 ARLAQRHG 652
Cdd:COG4251 472 KKIVERHG 479
|
|
| HAMP |
pfam00672 |
HAMP domain; |
377-446 |
1.85e-03 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 37.22 E-value: 1.85e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 377 VIARLMLRPLRVLRKTALDVAYTRLPEtvqailddpdpvnaskkavaPVPVDSRDEIGEVARSFDVVHEQ 446
Cdd:pfam00672 1 LLARRILRPLRRLAEAARRIASGDLDV--------------------RLPVSGRDEIGELARAFNQMAER 50
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| NIT |
pfam08376 |
Nitrate and nitrite sensing; The nitrate- and nitrite sensing domain (NIT) is found in ... |
107-343 |
4.95e-29 |
|
Nitrate and nitrite sensing; The nitrate- and nitrite sensing domain (NIT) is found in receptor components of signal transducing pathways in bacteria which control gene expression, cellular motility and enzyme activity in response to nitrate and nitrite concentrations. The NIT domain is predicted to be all alpha-helical in structure.
Pssm-ID: 462453 [Multi-domain] Cd Length: 227 Bit Score: 116.05 E-value: 4.95e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 107 VHDLQRERALAVIRVSSNDPLRQTG-LDAQIAKVDHDVDELRNAAVNLDSTDQAAsDRYAHGLQRLDALRPLREAMANG- 184
Cdd:pfam08376 1 VHALQKERGLSAGYLASGGGGRFAAeLAAQRAATDAALAALRAALAELALPARLA-DRLAALLRALDQLPALRRQVDAGa 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 185 YSDRAILDTYSSVLDALIQLGREVTTATTDRDLLRVGNSTQAISEAKEYILRGDSALQIAAFRNDFPGNLLDETRAAEAS 264
Cdd:pfam08376 80 LSALEALAAYTELIAALLDLVDELAAGSPDPELARQLRALAALLRAKEAAGQERALLAAALAAGRFTAAEYRRFLSLVAA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 916484329 265 GDAQISAFLTNATPDQVQLYNDTYSGPEVDERRRLQTQAfasaqqnkplnIEPTGLGQDSAVAADKLRAVEASLLSQMR 343
Cdd:pfam08376 160 QRAALAEFRAAATPEQRALYDATVTGPAVAAAERLRDRL-----------VDAAAWFAASTARIDLLREVEDRLADDLA 227
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
480-674 |
1.88e-25 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 106.14 E-value: 1.88e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 480 LGVIDRLEADEQ--DPDHLASLFELDHLATRLRRNGESLLVLSG--AGLAKSVPKPVPAADVIGAAVSEIEQYA-----R 550
Cdd:COG2205 35 LGAAELLLDEEDlsPEERRELLEIIRESAERLLRLIEDLLDLSRleSGKLSLELEPVDLAELLEEAVEELRPLAeekgiR 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 551 IEIGIVPEVAVQGLAIHDLVHVLAELLDNATYFSEPETKITVRAVITRKKALaIQVTDHGVGMSEERLAEVNERLADPPD 630
Cdd:COG2205 115 LELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARREGDGVR-ISVSDNGPGIPEEELERIFERFYRGDN 193
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 916484329 631 LDVSVTRRMGLYVVARLAQRHGIEVRLRENEDieGGVIARVVVP 674
Cdd:COG2205 194 SRGEGGTGLGLAIVKRIVEAHGGTIWVESEPG--GGTTFTVTLP 235
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
568-676 |
3.34e-16 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 75.48 E-value: 3.34e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 568 DLVHVLAELLDNATYFSEPETKITVRavITRKKALAIQVTDHGVGMSEERLAEVNERLADPPDLDVSVTrRMGLYVVARL 647
Cdd:pfam02518 5 RLRQVLSNLLDNALKHAAKAGEITVT--LSEGGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRGGGGT-GLGLSIVRKL 81
|
90 100
....*....|....*....|....*....
gi 916484329 648 AQRHGIEVRLRENEDieGGVIARVVVPME 676
Cdd:pfam02518 82 VELLGGTITVESEPG--GGTTVTLTLPLA 108
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
569-676 |
2.19e-15 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 73.07 E-value: 2.19e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 569 LVHVLAELLDNATYFSEPETKITVRaVITRKKALAIQVTDHGVGMSEERLAEVNERLADPPDLDVSVTRR-MGLYVVARL 647
Cdd:smart00387 6 LRQVLSNLLDNAIKYTPEGGRITVT-LERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRKIGGTgLGLSIVKKL 84
|
90 100
....*....|....*....|....*....
gi 916484329 648 AQRHGIEVRLRENEDieGGVIARVVVPME 676
Cdd:smart00387 85 VELHGGEISVESEPG--GGTTFTITLPLE 111
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
480-676 |
2.25e-15 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 78.41 E-value: 2.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 480 LGVIDRLEaDEQDPDHLASLFELDHLATRLRRNGESLLVLS--GAGLAKSVPKPVPAADVIGAAVSEIEQYARiEIGIVP 557
Cdd:COG0642 129 RGYLELLL-EELDEEQREYLETILRSADRLLRLINDLLDLSrlEAGKLELEPEPVDLAELLEEVVELFRPLAE-EKGIEL 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 558 EVAVQGLAIH------DLVHVLAELLDNATYFSEPETKITVRaVITRKKALAIQVTDHGVGMSEERLAEVNERL--ADPp 629
Cdd:COG0642 207 ELDLPDDLPTvrgdpdRLRQVLLNLLSNAIKYTPEGGTVTVS-VRREGDRVRISVEDTGPGIPPEDLERIFEPFfrTDP- 284
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 916484329 630 dldvSVTRR---MGLYVVARLAQRHGIEVRLRENEDieGGVIARVVVPME 676
Cdd:COG0642 285 ----SRRGGgtgLGLAIVKRIVELHGGTIEVESEPG--KGTTFTVTLPLA 328
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
514-674 |
1.23e-09 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 61.49 E-value: 1.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 514 ESLLVLS--GAGLAKSVPKPVPAADVIGAAVSEIEQYA-----RIEIGIVPE-VAVQGLAIHdLVHVLAELLDNATYFSE 585
Cdd:COG5002 220 NDLLDLSrlESGELKLEKEPVDLAELLEEVVEELRPLAeekgiELELDLPEDpLLVLGDPDR-LEQVLTNLLDNAIKYTP 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 586 PETKITVRAVITRKKALaIQVTDHGVGMSEERLAEVNERL--ADPpdldvSVTRRM-----GLYVVARLAQRHGIEVRLr 658
Cdd:COG5002 299 EGGTITVSLREEDDQVR-ISVRDTGIGIPEEDLPRIFERFyrVDK-----SRSRETggtglGLAIVKHIVEAHGGRIWV- 371
|
170
....*....|....*.
gi 916484329 659 ENEdIEGGVIARVVVP 674
Cdd:COG5002 372 ESE-PGKGTTFTITLP 386
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
489-671 |
3.05e-09 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 60.43 E-value: 3.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 489 DEQDPDHlaSLFELDHLATRLRRNGESLLVLS----GAGLAKSVPkpVPAADVIGAAVSEI---EQYARIEIGI---VPE 558
Cdd:PRK10337 268 DPQARKK--ALLQLHAGIDRATRLVDQLLTLSrldsLDNLQDVAE--IPLEDLLQSAVMDIyhtAQQAGIDVRLtlnAHP 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 559 VAVQGLAIhdLVHVLAE-LLDNATYFSEPETKITVRAvitrkKALAIQVTDHGVGMSEERLAEVNERLADPPDLDVSVTr 637
Cdd:PRK10337 344 VIRTGQPL--LLSLLVRnLLDNAIRYSPQGSVVDVTL-----NARNFTVRDNGPGVTPEALARIGERFYRPPGQEATGS- 415
|
170 180 190
....*....|....*....|....*....|....
gi 916484329 638 RMGLYVVARLAQRHGIEVRLRENEdiEGGVIARV 671
Cdd:PRK10337 416 GLGLSIVRRIAKLHGMNVSFGNAP--EGGFEAKV 447
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
496-676 |
1.68e-08 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 57.94 E-value: 1.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 496 LASLFELDHLATRLRRNGESLLVLSGAGLAKsVPKPVPAADVIGAAVSEIEQYARIEIGIVPEVAVQGLAIHDLVHVLAE 575
Cdd:COG3290 210 LLQLGEYDEALEYIDEISEELQELIDSLLSR-IGNPVLAALLLGKAARARERGIDLTIDIDSDLPDLPLSDTDLVTILGN 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 576 LLDNA----TYFSEPETKITVRaVITRKKALAIQVTDHGVGMSEERLAEVNERladppdlDVSvTRR-----MGLYVVAR 646
Cdd:COG3290 289 LLDNAieavEKLPEEERRVELS-IRDDGDELVIEVEDSGPGIPEELLEKIFER-------GFS-TKLgegrgLGLALVKQ 359
|
170 180 190
....*....|....*....|....*....|
gi 916484329 647 LAQRHGIEVRLRENEdiEGGVIARVVVPME 676
Cdd:COG3290 360 IVEKYGGTIEVESEE--GEGTVFTVRLPKE 387
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
576-676 |
6.14e-08 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 56.56 E-value: 6.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 576 LLDNATYF----SEPETKITVRAvITRKKALAIQVTDHGVGMSEERLAEVNERLADPPDldvsvTRRMGLY-VVARLAQR 650
Cdd:COG2972 344 LVENAIEHgiepKEGGGTIRISI-RKEGDRLVITVEDNGVGMPEEKLEKLLEELSSKGE-----GRGIGLRnVRERLKLY 417
|
90 100
....*....|....*....|....*.
gi 916484329 651 HGIEVRLRENEDIEGGVIARVVVPME 676
Cdd:COG2972 418 YGEEYGLEIESEPGEGTTVTIRIPLE 443
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
423-674 |
6.69e-08 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 56.39 E-value: 6.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 423 APVPVDSRDEIGEVARSFDVVHEQ-----------------------AVKMAAEqaLLRENVNG----IFV-NL---SRR 471
Cdd:PRK11100 226 VPLPKLGSSELRELAQALESMRVKlegkayveqyvqtlthelksplaAIRGAAE--LLQEDPPPedraRFTgNIltqSAR 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 472 SQRLVERQLgVIDRLEAdEQDPDHLASLfELDHLATRLRRNGESLLVlsgaglAKSVpkpvpaadvigaavseieqyaRI 551
Cdd:PRK11100 304 LQQLIDRLL-ELARLEQ-RQELEVLEPV-ALAALLEELVEAREAQAA------AKGI---------------------TL 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 552 EIGIvPEVAVQGLAihDLVH-VLAELLDNATYFSEPETKITVRAViTRKKALAIQVTDHGVGMSEERLAEVNER---LAD 627
Cdd:PRK11100 354 RLRP-DDARVLGDP--FLLRqALGNLLDNAIDFSPEGGTITLSAE-VDGEQVALSVEDQGPGIPDYALPRIFERfysLPR 429
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 916484329 628 PPDLDVSVTrrMGLYVVARLAQRHGIEVRLRENEdiEGGVIARVVVP 674
Cdd:PRK11100 430 PANGRKSTG--LGLAFVREVARLHGGEVTLRNRP--EGGVLATLTLP 472
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
559-661 |
6.35e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 46.25 E-value: 6.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 559 VAVQGLAIHdLVHVLAELLDNATYFSEPETKITVRavITRKKALAIQVTDHGVGMSEERLAEVNERLADPPDLDVSVTRr 638
Cdd:cd16940 5 IQVQGDALL-LFLLLRNLVDNAVRYSPQGSRVEIK--LSADDGAVIRVEDNGPGIDEEELEALFERFYRSDGQNYGGSG- 80
|
90 100
....*....|....*....|...
gi 916484329 639 MGLYVVARLAQRHGIEVRLRENE 661
Cdd:cd16940 81 LGLSIVKRIVELHGGQIFLGNAQ 103
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
198-652 |
1.45e-05 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 49.01 E-value: 1.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 198 LDALIQLGREVTTATTDRDLLRVGNSTQAISEAKEYILRGDSALQIAAFRNDFPGNLLDETRAAEASGDAQISAFLTNAT 277
Cdd:COG4251 9 LLLLLLLLLLLLLLLLLLVLLLALALLLLLALLVLLLLLIRLLLLLLLSLLALLLLLLLLLLLLLVLAALALLLLLLLLE 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 278 PDQVQLYNDTYSGPEVDERRRLQTQAFASAQQNKPLNIEPTGLGQDSAVAADKLRAVEASLLSQMRAQADSLASNAVRSA 357
Cdd:COG4251 89 LALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALIL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 358 WVAGVVVLAALIAALMLMLVIARLMLRPLRVLRKTALDVAYTRLPETVQAILDDPDPVNASKKAVAPVPVDSRDEIGEVA 437
Cdd:COG4251 169 ALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLL 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 438 RSFDVVHEQAVKMAAEQALLRENVngifVNLSRRSQRL-----------------VERQLGVIDRLEADEQDPDHLASLF 500
Cdd:COG4251 249 ILVLELLELRLELEELEEELEERT----AELERSNEELeqfayvashdlreplrkISGFSQLLEEDYGDKLDEEGREYLE 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 501 ELDHLATRLRRNGESLLVLSGAGLAKSVPKPVPAADVIGAAVSEIEQY-----ARIEIGIVPEVavQGLAIHdLVHVLAE 575
Cdd:COG4251 325 RIRDAAERMQALIDDLLAYSRVGRQELEFEPVDLNELLEEVLEDLEPRieergAEIEVGPLPTV--RGDPTL-LRQVFQN 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 576 LLDNATYFSEPET--KITVRAVItRKKALAIQVTDHGVGMSE---ERLAEVNERLadppdldvsVTRR------MGLYVV 644
Cdd:COG4251 402 LISNAIKYSRPGEppRIEIGAER-EGGEWVFSVRDNGIGIDPeyaEKIFEIFQRL---------HSRDeyegtgIGLAIV 471
|
....*...
gi 916484329 645 ARLAQRHG 652
Cdd:COG4251 472 KKIVERHG 479
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
424-681 |
4.72e-05 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 46.88 E-value: 4.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 424 PVPVDSR-DEIGEVARSF-------------------DVVHEqavkmaaeqalLRENVNGIFVNLsrrsqRLVERQlGVI 483
Cdd:PRK10755 106 PIAIHSStLEIEAVTSALnqlvsrltstldqerlftaDVAHE-----------LRTPLAGIRLHL-----ELLEKQ-HHI 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 484 DrleadeqdpdhLASLFE-LDHLAtrlrRNGESLLVLSGAG--LAKSVPKPVP-AADVIGAAVSEIEQYA--RIEIGIVP 557
Cdd:PRK10755 169 D-----------VAPLIArLDQMM----HTVEQLLQLARAGqsFSSGHYQTVKlLEDVILPSQDELSEMLeqRQQTLLLP 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 558 EVA----VQGLAIHdLVHVLAELLDNATYFSEPETKITVRaVITRKKALAIQVTDHGVGMSEERLAEVNERLadppdldv 633
Cdd:PRK10755 234 ESAaditVQGDATL-LRLLLRNLVENAHRYSPEGSTITIK-LSQEDGGAVLAVEDEGPGIDESKCGELSKAF-------- 303
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 916484329 634 svtRRM---------GLYVVARLAQRHGIEVRLRENEDiEGGVIARVVVPMELLTQV 681
Cdd:PRK10755 304 ---VRMdsryggiglGLSIVSRITQLHHGQFFLQNRQE-RSGTRAWVWLPKAQNVAN 356
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
572-658 |
5.44e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 43.25 E-value: 5.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 572 VLAELLDNATYFSEpETKITVRAVITRKK----ALAIQVTDHGVGMSEERLAevneRLADP-PDLDVSVTRR-----MGL 641
Cdd:cd16922 4 ILLNLLGNAIKFTE-EGEVTLRVSLEEEEedgvQLRFSVEDTGIGIPEEQQA----RLFEPfSQADSSTTRKyggtgLGL 78
|
90
....*....|....*..
gi 916484329 642 YVVARLAQRHGIEVRLR 658
Cdd:cd16922 79 AISKKLVELMGGDISVE 95
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
522-676 |
8.42e-05 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 46.11 E-value: 8.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 522 AGLAKSVPKPVPAADVIGAAVSEIE-QYARIEIGIVPEVAVQGLAIH-D---LVHVLAELLDNATYFSEPETKITVRAvI 596
Cdd:COG5000 266 ARLPEPQLEPVDLNELLREVLALYEpALKEKDIRLELDLDPDLPEVLaDrdqLEQVLINLLKNAIEAIEEGGEIEVST-R 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 597 TRKKALAIQVTDHGVGMSEERLaevnERLADPpdlDVSvTRR----MGLYVVARLAQRHGIEVRLRENEDieGGVIARVV 672
Cdd:COG5000 345 REDGRVRIEVSDNGPGIPEEVL----ERIFEP---FFT-TKPkgtgLGLAIVKKIVEEHGGTIELESRPG--GGTTFTIR 414
|
....
gi 916484329 673 VPME 676
Cdd:COG5000 415 LPLA 418
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
569-669 |
1.29e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 42.06 E-value: 1.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 569 LVHVLAELLDNATYFSEPETKITVRAVITRKKAlAIQVTDHGVGMSEERLAEVNER---LADPPDLDVSVTrrMGLYVVA 645
Cdd:cd16945 5 LRQAINNLLDNAIDFSPEGGLIALQLEADTEGI-ELLVFDEGSGIPDYALNRVFERfysLPRPHSGQKSTG--LGLAFVQ 81
|
90 100
....*....|....*....|....
gi 916484329 646 RLAQRHGIEVRLReneDIEGGVIA 669
Cdd:cd16945 82 EVAQLHGGRITLR---NRPDGVLA 102
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
137-657 |
2.45e-04 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 45.06 E-value: 2.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 137 AKVDHDVDELRNAAVNLDSTD--QAASDRYAHGLQRLDALRP-LREAMANGYSDRAILDT----------YSSVLDALIQ 203
Cdd:COG4192 58 LKLEENSNELVAALPEFAAATntTERSQLRNQLNTQLADIEElLAELEQLTQDAGDLRAAvadlrnllqqLDSLLTQRIA 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 204 LGREVTTATTDRDLLRvgnstQAISEAKEYiLRGDSALQIAAFRNDFPGNLLDETRAAEASGDAQISA-----------F 272
Cdd:COG4192 138 LRRRLQELLEQINWLH-----QDFNSELTP-LLQEASWQQTRLLDSVETTESLRNLQNELQLLLRLLAienqivsllreV 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 273 LTNATPDQVQLYNDTYS----------------GPEVDERRRLQT-QAFASAQQNKP--------LNIEPTGLGQDSAVA 327
Cdd:COG4192 212 AAARDQADVDNLFDRLQylkdeldrnlqalknyPSTITLRQLIDElLAIGSGEGGLPslrrdelaAQATLEALAEENNSI 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 328 ADKLRAVEASLLSQMRAQADSLASNAVRSAWVAGVVVLAALIAALMLMLVIARLMLRPLRVLRktaldvaYTRLPETVQA 407
Cdd:COG4192 292 LEQLRTQISGLVGNSREQLVALNQETAQLVQQSGILLLAIALLSLLLAVLINYFYVRRRLVKR-------LNALSDAMAA 364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 408 IlddpdpvnASKKAVAPVPVDSRDEIGEVARSFDVVHEQAVkmAAEQALLRENVNGIfvnlsRRSQRLVERQLGVID--- 484
Cdd:COG4192 365 I--------AAGDLDVPIPVDGNDEIGRIARLLRVFRDQAI--EKTQELETEIEERK-----RIEKNLRQTQDELIQaak 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 485 -------------------------------RLEAdEQDPDHLASLFELDHLATRLRRNGESLLVLSGAGLAKSVpkPVP 533
Cdd:COG4192 430 mavvgqtmtslahelnqplnamsmylfsakkALEQ-ENYAQLPTSLDKIEGLIERMDKIIKSLRQFSRKSDTPLQ--PVD 506
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 534 AADVIGAAVSEIEQYAR---IEIGIVPEVAVQGLAIHdLVHVLAELLDNATYFSEPETKITVRAVITRKKaLAIQVTDHG 610
Cdd:COG4192 507 LRQVIEQAWELVESRAKpqqITLHIPDDLMVQGDQVL-LEQVLVNLLVNALDAVATQPQISVDLLSNAEN-LRVAISDNG 584
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 916484329 611 VGMseerlaEVNERLADPPDLDVSVTRRMGLYVVARLAQRHGIEVRL 657
Cdd:COG4192 585 NGW------PLVDKLFTPFTTTKEVGLGLGLSICRSIMQQFGGDLYL 625
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
484-675 |
1.17e-03 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 42.48 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 484 DRLEADEQDPDHLASLFELDHLATRLRRNGESLLVLSGAGlaKSVPKPVPAADVIGAAVS----EIEQY-ARIEIGIVPE 558
Cdd:COG4191 169 RRLEDEPDPEELREALERILEGAERAAEIVRSLRAFSRRD--EEEREPVDLNELIDEALEllrpRLKARgIEVELDLPPD 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 559 V-AVQGLAIHdLVHVLAELLDNATY-FSEPET-KITVRAVITRKKALaIQVTDHGVGMSEERLaevnERLADPpdlDVSv 635
Cdd:COG4191 247 LpPVLGDPGQ-LEQVLLNLLINAIDaMEEGEGgRITISTRREGDYVV-ISVRDNGPGIPPEVL----ERIFEP---FFT- 316
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 916484329 636 TRR------MGLYVVARLAQRHG--IEVrlrENEdIEGGVIARVVVPM 675
Cdd:COG4191 317 TKPvgkgtgLGLSISYGIVEKHGgrIEV---ESE-PGGGTTFTITLPL 360
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
572-674 |
1.38e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 39.35 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 572 VLAELLDNATYFSEPETKItvrAVITRKKALAIQVTDHGVGMSEERLAEVNERLADPPDLDVSVTRRMGLYVVARLAQRH 651
Cdd:cd16950 4 VLSNLVDNALRYGGGWVEV---SSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNARGTSGTGLGLAIVQRISDAH 80
|
90 100
....*....|....*....|...
gi 916484329 652 GIEVRLRENEdiEGGVIARVVVP 674
Cdd:cd16950 81 GGSLTLANRA--GGGLCARIELP 101
|
|
| HAMP |
pfam00672 |
HAMP domain; |
377-446 |
1.85e-03 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 37.22 E-value: 1.85e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 377 VIARLMLRPLRVLRKTALDVAYTRLPEtvqailddpdpvnaskkavaPVPVDSRDEIGEVARSFDVVHEQ 446
Cdd:pfam00672 1 LLARRILRPLRRLAEAARRIASGDLDV--------------------RLPVSGRDEIGELARAFNQMAER 50
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
572-628 |
4.57e-03 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 40.73 E-value: 4.57e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 916484329 572 VLAELLDNATYFSEPETKITVRAVITRKKALAIQVTDHGVGMSEERLaevnERLADP 628
Cdd:COG5809 383 VFINLLKNAIEAMPEGGNITIETKAEDDDKVVISVTDEGCGIPEERL----KKLGEP 435
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
569-665 |
7.48e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 37.31 E-value: 7.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916484329 569 LVHVLAELLDNATYFSEPET--KITVRAVITrKKALAIQVTDHGVGMSE---ERLAEVNERLADPPDLDVSvtrRMGLYV 643
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRRppRIEVGAEDV-GEEWTFYVRDNGIGIDPeyaEKVFGIFQRLHSREEYEGT---GVGLAI 76
|
90 100
....*....|....*....|..
gi 916484329 644 VARLAQRHGIEVRLrENEDIEG 665
Cdd:cd16921 77 VRKIIERHGGRIWL-ESEPGEG 97
|
|
| |
