NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|940642111|ref|WP_055015069|]
View 

protein translocase subunit SecF [Pseudoalteromonas sp. P1-13-1a]

Protein Classification

protein translocase subunit SecF( domain architecture ID 1012476)

protein translocase subunit SecF is part of the Sec protein translocase complex; SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA

Gene Ontology:  GO:0015450|GO:0043952
TCDB:  2.A.6.4

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
secF super family cl36212
preprotein translocase subunit SecF; Reviewed
 6-310 2.20e-136

preprotein translocase subunit SecF; Reviewed


The actual alignment was detected with superfamily member PRK13021:

Pssm-ID: 237274 [Multi-domain]  Cd Length: 297  Bit Score: 388.06  E-value: 2.20e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111   6 LKGEAGSRLRFFGMLLSAILVLLSVFTLSQKGLNFGLDFTGGYLTEFTTSQGVELKELQSFITKNHNGEFELTAQGN-SH 84
Cdd:PRK13021   1 MKNINLTKWRYISSAISIVLMLLSLTIIGVKGFNWGLDFTGGVVTEVQLDRKITSSELQPLLNAAYQQEVSVISASEpGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  85 FQLREAPSDSTANSNDWQTAITQNADiNAEVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWRLAVGSVVAL 164
Cdd:PRK13021  81 WVLRYAPADTAQSNVDIQQALAPLGT-EVQVLNSSIVGPQVGQELAEQGGLALLVAMLCILGYLSYRFEWRLASGALFAL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 165 VHDLLLVLGLFSLFQLEFNLTVLASLLAIIGYSLNDSIIVGDRVRELLRVKSNnaLSPASIINSAIKSTLTRTLITSGTT 244
Cdd:PRK13021 160 VHDVIFVLAFFALTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPK--LAIQEINNQAIVATFSRTMVTSGTT 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 940642111 245 LATVASVWLLAGAPLQGFAIALFTGIVVGTFSSICIAATLPELLGLSAENYEEKLdvktqaLMDMP 310
Cdd:PRK13021 238 LMTVGALWIMGGGPLEGFSIAMFIGILTGTFSSISVGTSLPELLGLSPEHYKVQV------ISDTP 297
 
Name Accession Description Interval E-value
secF PRK13021
preprotein translocase subunit SecF; Reviewed
 6-310 2.20e-136

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 237274 [Multi-domain]  Cd Length: 297  Bit Score: 388.06  E-value: 2.20e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111   6 LKGEAGSRLRFFGMLLSAILVLLSVFTLSQKGLNFGLDFTGGYLTEFTTSQGVELKELQSFITKNHNGEFELTAQGN-SH 84
Cdd:PRK13021   1 MKNINLTKWRYISSAISIVLMLLSLTIIGVKGFNWGLDFTGGVVTEVQLDRKITSSELQPLLNAAYQQEVSVISASEpGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  85 FQLREAPSDSTANSNDWQTAITQNADiNAEVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWRLAVGSVVAL 164
Cdd:PRK13021  81 WVLRYAPADTAQSNVDIQQALAPLGT-EVQVLNSSIVGPQVGQELAEQGGLALLVAMLCILGYLSYRFEWRLASGALFAL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 165 VHDLLLVLGLFSLFQLEFNLTVLASLLAIIGYSLNDSIIVGDRVRELLRVKSNnaLSPASIINSAIKSTLTRTLITSGTT 244
Cdd:PRK13021 160 VHDVIFVLAFFALTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPK--LAIQEINNQAIVATFSRTMVTSGTT 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 940642111 245 LATVASVWLLAGAPLQGFAIALFTGIVVGTFSSICIAATLPELLGLSAENYEEKLdvktqaLMDMP 310
Cdd:PRK13021 238 LMTVGALWIMGGGPLEGFSIAMFIGILTGTFSSISVGTSLPELLGLSPEHYKVQV------ISDTP 297
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 13-291 8.60e-90

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 269.23  E-value: 8.60e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  13 RLRFFGMLLSAILVLLSVFTLSQKGLNFGLDFTGGYLTEFTTSQGVELKELQSFITKNHNGEFELTAQGNSH---FQLRE 89
Cdd:COG0341   13 KKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTFGSDNdvlIRTPP 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  90 APSDSTANSNDWQTAITQNADiNAEVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWRLAVGSVVALVHDLL 169
Cdd:COG0341   93 LDGESAEEVEKVRAALKEAFG-DVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRFEWRFAVGAVVALLHDVL 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 170 LVLGLFSLFQLEFNLTVLASLLAIIGYSLNDSIIVGDRVRELLRVKSNnaLSPASIINSAIKSTLTRTLITSGTTLATVA 249
Cdd:COG0341  172 ITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRK--MTLAEIINLSINQTLSRTINTSLTTLLVVL 249

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 940642111 250 SVWLLAGAPLQGFAIALFTGIVVGTFSSICIAATLPELLGLS 291
Cdd:COG0341  250 ALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLLLWLGKR 291
3a0501s07 TIGR00966
protein-export membrane protein SecF; This bacterial protein is always found with the ...
 37-281 1.72e-64

protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273368 [Multi-domain]  Cd Length: 246  Bit Score: 203.27  E-value: 1.72e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111   37 GLNFGLDFTGGYLTEFTTSQGVELKELQSFITKNHNGEFELTAQGNSHFQLREAPSDSTANSNDWQTAIT---QNADINA 113
Cdd:TIGR00966   1 GFNFGIDFTGGTVIETRLEQAADVAEVRDVLEKAGIEGVVIQEFGSSHTIMIRIPTLDTEQSEELREALEealKNVDPDA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  114 EVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWRLAVGSVVALVHDLLLVLGLFSLFQLEFNLTVLASLLAI 193
Cdd:TIGR00966  81 EIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTVAALLTI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  194 IGYSLNDSIIVGDRVRELLRVKSNNalSPASIINSAIKSTLTRTLITSGTTLATVASVWLLAGAPLQGFAIALFTGIVVG 273
Cdd:TIGR00966 161 IGYSINDTVVVFDRIRENLRKYTRK--TFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVGVIVG 238


                  ....*...
gi 940642111  274 TFSSICIA 281
Cdd:TIGR00966 239 TYSSIFIA 246
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 102-284 4.59e-53

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 172.02  E-value: 4.59e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  102 QTAITQNADINAEVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWRLAVGSVVALVHDLLLVLGLFSLFQLE 181
Cdd:pfam02355   2 VEALLKNVGPDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLFGIE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  182 FNLTVLASLLAIIGYSLNDSIIVGDRVRELLRVKSNNalSPASIINSAIKSTLTRTLITSGTTLATVASVWLLAGAPLQG 261
Cdd:pfam02355  82 VDLATVAALLTIIGYSVNDTVVVFDRVRENLRKKTRA--TLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKD 159

                         170       180
                  ....*....|....*....|...
gi 940642111  262 FAIALFTGIVVGTFSSICIAATL 284
Cdd:pfam02355 160 FSLALLVGVIVGTYSSIFIASPI 182
 
Name Accession Description Interval E-value
secF PRK13021
preprotein translocase subunit SecF; Reviewed
 6-310 2.20e-136

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 237274 [Multi-domain]  Cd Length: 297  Bit Score: 388.06  E-value: 2.20e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111   6 LKGEAGSRLRFFGMLLSAILVLLSVFTLSQKGLNFGLDFTGGYLTEFTTSQGVELKELQSFITKNHNGEFELTAQGN-SH 84
Cdd:PRK13021   1 MKNINLTKWRYISSAISIVLMLLSLTIIGVKGFNWGLDFTGGVVTEVQLDRKITSSELQPLLNAAYQQEVSVISASEpGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  85 FQLREAPSDSTANSNDWQTAITQNADiNAEVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWRLAVGSVVAL 164
Cdd:PRK13021  81 WVLRYAPADTAQSNVDIQQALAPLGT-EVQVLNSSIVGPQVGQELAEQGGLALLVAMLCILGYLSYRFEWRLASGALFAL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 165 VHDLLLVLGLFSLFQLEFNLTVLASLLAIIGYSLNDSIIVGDRVRELLRVKSNnaLSPASIINSAIKSTLTRTLITSGTT 244
Cdd:PRK13021 160 VHDVIFVLAFFALTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPK--LAIQEINNQAIVATFSRTMVTSGTT 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 940642111 245 LATVASVWLLAGAPLQGFAIALFTGIVVGTFSSICIAATLPELLGLSAENYEEKLdvktqaLMDMP 310
Cdd:PRK13021 238 LMTVGALWIMGGGPLEGFSIAMFIGILTGTFSSISVGTSLPELLGLSPEHYKVQV------ISDTP 297
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 13-291 8.60e-90

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 269.23  E-value: 8.60e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  13 RLRFFGMLLSAILVLLSVFTLSQKGLNFGLDFTGGYLTEFTTSQGVELKELQSFITKNHNGEFELTAQGNSH---FQLRE 89
Cdd:COG0341   13 KKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTFGSDNdvlIRTPP 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  90 APSDSTANSNDWQTAITQNADiNAEVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWRLAVGSVVALVHDLL 169
Cdd:COG0341   93 LDGESAEEVEKVRAALKEAFG-DVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRFEWRFAVGAVVALLHDVL 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 170 LVLGLFSLFQLEFNLTVLASLLAIIGYSLNDSIIVGDRVRELLRVKSNnaLSPASIINSAIKSTLTRTLITSGTTLATVA 249
Cdd:COG0341  172 ITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRK--MTLAEIINLSINQTLSRTINTSLTTLLVVL 249

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 940642111 250 SVWLLAGAPLQGFAIALFTGIVVGTFSSICIAATLPELLGLS 291
Cdd:COG0341  250 ALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLLLWLGKR 291
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 13-284 2.28e-69

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 229.35  E-value: 2.28e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  13 RLRFFGMLLSAILVLLSVFTLSQKGLNFGLDFTGGYLTEFTTSQGVELKELQSFITKNHNGEFELTAQGNSH----FQLR 88
Cdd:PRK13024 453 KKRKWFLIFSIVLVIAGIIIFFIFGLNLGIDFTGGTRYEIRTDQPVDLEQVRADLKELGLGEVNIVTFGSDNnqvlVRTY 532

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  89 EAPSDSTANSNDWQTAITQNAD--INAEVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWRLAVGSVVALVH 166
Cdd:PRK13024 533 GILSDDEEADTEIVAKLKNALKndKGGTIPSSETVGPTVGKELARNAIIAVLIALIGILLYILIRFEWTFSLGAILALLH 612

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 167 DLLLVLGLFSLFQLEFNLTVLASLLAIIGYSLNDSIIVGDRVRELLRVKSNNALspASIINSAIKSTLTRTLITSGTTLA 246
Cdd:PRK13024 613 DVLIVIGFFSLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIRENLRLYKKKDL--REIVNKSINQTLSRTINTSLTTLL 690

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 940642111 247 TVASVWLLAGAPLQGFAIALFTGIVVGTFSSICIAATL 284
Cdd:PRK13024 691 VLLALLIFGGSSLRNFSLALLVGLIVGTYSSIFIAAPL 728
3a0501s07 TIGR00966
protein-export membrane protein SecF; This bacterial protein is always found with the ...
 37-281 1.72e-64

protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273368 [Multi-domain]  Cd Length: 246  Bit Score: 203.27  E-value: 1.72e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111   37 GLNFGLDFTGGYLTEFTTSQGVELKELQSFITKNHNGEFELTAQGNSHFQLREAPSDSTANSNDWQTAIT---QNADINA 113
Cdd:TIGR00966   1 GFNFGIDFTGGTVIETRLEQAADVAEVRDVLEKAGIEGVVIQEFGSSHTIMIRIPTLDTEQSEELREALEealKNVDPDA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  114 EVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWRLAVGSVVALVHDLLLVLGLFSLFQLEFNLTVLASLLAI 193
Cdd:TIGR00966  81 EIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTVAALLTI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  194 IGYSLNDSIIVGDRVRELLRVKSNNalSPASIINSAIKSTLTRTLITSGTTLATVASVWLLAGAPLQGFAIALFTGIVVG 273
Cdd:TIGR00966 161 IGYSINDTVVVFDRIRENLRKYTRK--TFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVGVIVG 238


                  ....*...
gi 940642111  274 TFSSICIA 281
Cdd:TIGR00966 239 TYSSIFIA 246
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 102-284 4.59e-53

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 172.02  E-value: 4.59e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  102 QTAITQNADINAEVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWRLAVGSVVALVHDLLLVLGLFSLFQLE 181
Cdd:pfam02355   2 VEALLKNVGPDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLFGIE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  182 FNLTVLASLLAIIGYSLNDSIIVGDRVRELLRVKSNNalSPASIINSAIKSTLTRTLITSGTTLATVASVWLLAGAPLQG 261
Cdd:pfam02355  82 VDLATVAALLTIIGYSVNDTVVVFDRVRENLRKKTRA--TLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKD 159

                         170       180
                  ....*....|....*....|...
gi 940642111  262 FAIALFTGIVVGTFSSICIAATL 284
Cdd:pfam02355 160 FSLALLVGVIVGTYSSIFIASPI 182
PRK14726 PRK14726
protein translocase subunit SecDF;
10-305 2.37e-51

protein translocase subunit SecDF;


Pssm-ID: 237805 [Multi-domain]  Cd Length: 855  Bit Score: 181.07  E-value: 2.37e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  10 AGSRLRFFGM-----LLSAILVLLSVFTLSQKGLNFGLDFTGGYLTEFTTSQGV-ELKELQSFITKNHNGEFELTAQGN- 82
Cdd:PRK14726 543 EGANIRFMGIrryvfTLSAALSLASLVLFATVGLNLGIDFTGGSLIEVRAKQGNaDIADIRARLNELNLGEVQVERFGSp 622

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  83 SHFQLREAPSDSTANSNdwQTAITQnadINAEvLSSAY-------IGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWR 155
Cdd:PRK14726 623 RDALIRIASQDGGENAE--QSAVTL---VRGE-LEDDYdfrrvevVGPAVSGELTMAATLGVLAALAAILIYIWIRFEWQ 696

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 156 LAVGSVVALVHDLLLVLGLFSLFQLEFNLTVLASLLAIIGYSLNDSIIVGDRVRELLRVKSNNALSpaSIINSAIKSTLT 235
Cdd:PRK14726 697 FAVGAIIATLHDVILTLGLFVLTGIEFNLTSIAAILTIVGYSLNDTVVVYDRVRENLRRYKKMPLP--ILIDASINQTLS 774

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 236 RTLITSGTTLATVASVWLLAGAPLQGFAIALFTGIVVGTFSSICIAATLPELLGLSAENYEEKLDVKTQA 305
Cdd:PRK14726 775 RTVLTSATTLLALLALYLFGGEVIRSFTFAMLFGVAVGTFSSIYIAAPVLIVFKLRPESLDGEESNKTDA 844
2A0604s01 TIGR00916
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ...
 112-278 1.86e-42

protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273336 [Multi-domain]  Cd Length: 192  Bit Score: 144.71  E-value: 1.86e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  112 NAEVLSSAYIG---SQVGDELFEQGCLALFSAMVAVMLYLAVRFEWRLAVGSVVALVHDLLLVLGLFSLFQLEFNLTVLA 188
Cdd:TIGR00916  25 NAKVISAPVVGtvgPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDVILILGVLSLFGATLTLPGIA 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  189 SLLAIIGYSLNDSIIVGDRVRELLRVKSNNalSPASIINSAIKSTLTRTLITSGTTLATVASVWLLAGAPLQGFAIALFT 268
Cdd:TIGR00916 105 GLLTIIGYSVDDTVVIFDRIREELRKYKGR--TFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGI 182

                         170
                  ....*....|
gi 940642111  269 GIVVGTFSSI 278
Cdd:TIGR00916 183 GVIAGTYSSI 192
PRK13023 PRK13023
protein translocase subunit SecDF;
13-290 9.36e-33

protein translocase subunit SecDF;


Pssm-ID: 171842 [Multi-domain]  Cd Length: 758  Bit Score: 127.81  E-value: 9.36e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  13 RLRFFGMLLSAILVLLSVFTLSQKGLNFGLDFTGGYLTEFTTSQG-VELKELQSFITKNHNGEFELTAQGNSHFQLREAP 91
Cdd:PRK13023 457 RLQFVTLGISVLACAIVVALFVNIGFNYGIDFRGGSMVELQARNGdANLEDINERLAELNIDSARVLPAKSPRSALVIIG 536

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  92 SDSTANSNDWQTAITQNADINAE--VLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWRLAVGSVVALVHDLL 169
Cdd:PRK13023 537 SQEVGDDAEQTVAVKLRGEFEQDysFQRVDVVGPTVSEQLSRAGVLAVILSLIGIFIYVWFRFRWQLALGAVLSTLHDVV 616

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 170 LVLGLFSLFQLEFNLTVLASLLAIIGYSLNDSIIVGDRVRELLRVKSNNALspASIINSAIKSTLTRTLITSGTTLATVA 249
Cdd:PRK13023 617 ILSGMFIVFRMEFNLWSVAAILTIIGYSLNDTVVIYDRVRENLRRYKSAPL--PAIIDASINQTLSRTLLTSFVTFLAHV 694

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 940642111 250 SVWLLAGAPLQGFAIALFTGIVVGTFSSICIAATLPELLGL 290
Cdd:PRK13023 695 PLYAFGGSEIRMFALALSVGIIVASYSSIFIAAPLLVQFGL 735
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 29-288 6.71e-27

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 111.10  E-value: 6.71e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111   29 SVFTLSQKGLNFG-------LDFTGGYLTEFTTSQ--GVELKELQSFITKN------HNGEFELTAQGNS-----HFQLR 88
Cdd:PRK12911 1096 SVLVLGCVALGFGawnsvlgMDFKGGYALTLDPSDvcEYDVEQMRSKLRKKfqqiglSSRDFRIRTFDSSekikiYFSQN 1175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111   89 -----EAPSDSTANSNDWQTAIT------QNADINAEVLSSAY-----IGSQVGDELFEQGCLALFSAMVAVMLYLAVRF 152
Cdd:PRK12911 1176 aldrvEAIEGAGSEQSDHHLALVlgvlsdTGSDTSSEVFDATQnfwfkVSGQLSNKMRTQAVIALFGALGIILLYVSLRF 1255

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  153 EWRLAVGSVVALVHDLLLVLGLFSLF-----QLEFNLTVLASLLAIIGYSLNDSIIVGDRVRELLRVKsnnALSPASI-I 226
Cdd:PRK12911 1256 EWRYAFSAICALIHDLLATCAVLVALhfflqKIQIDLQAIGALMTVLGYSLNNTLIIFDRIREDRQEK---LFTPMPIlI 1332

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 940642111  227 NSAIKSTLTRTLITSGTTLATVASVWLLAGAPLQGFAIALFTGIVVGTFSSICIAatlPELL 288
Cdd:PRK12911 1333 NDALQKTLGRTVMTTATTLSVLLILLFVGGGSIFNFAFIMTIGILLGTLSSLYIA---PPLL 1391
secD TIGR01129
protein-export membrane protein SecD; Members of this family are highly variable in length ...
 114-284 2.40e-10

protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273456 [Multi-domain]  Cd Length: 397  Bit Score: 60.76  E-value: 2.40e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  114 EVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWrLAVGSVVALVHDLLLVLGLFSLFQLEFNLTVLASLLAI 193
Cdd:TIGR01129 231 QILEERTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRL-FGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILT 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  194 IGYSLNDSIIVGDRVRELLRvksnNALSPASIINSAIKSTLTRTLITSGTTLATVASVWLLAGAPLQGFAIALFTGIVVG 273
Cdd:TIGR01129 310 IGMAVDANVLIYERIKEELR----LGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIAS 385

                         170
                  ....*....|.
gi 940642111  274 TFSSICIAATL 284
Cdd:TIGR01129 386 LFTALVFTRLL 396
PRK08578 PRK08578
preprotein translocase subunit SecF; Reviewed
 20-258 4.46e-09

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 236302 [Multi-domain]  Cd Length: 292  Bit Score: 56.48  E-value: 4.46e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  20 LLSAILVLLSVFTLSQKGLNFGLDFTGGylTEFT-TSQGVELKELQSFITKNhnGEFELTAQGNSHFQLREAPSDSTANS 98
Cdd:PRK08578  24 LLLSLLLLGGTFATTGSPVKLGIDFTGG--TEITiQTNDASPDELESALSGE--PGVDVRKGSGNGYIITFGSGDDTDVD 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  99 --NDWQTAITQNADINAEVLSSAYIGSQVGDELFEQGCLAL---FSAMvAVMLYLAVR-FEWRLAVgsVVALVHDLLLVL 172
Cdd:PRK08578 100 klADAVKEFFNVDSISELNYSEKQIGPTFGSQFQEQALKAVgfaFIGM-AVVVFLIFRtPVPSLAV--ILSAFSDIIIAL 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 173 GLFSLFQLEFNLTVLASLLAIIGYSLNDSIIVGDRVrelLRVKSNnalspasiINSAIKSTLTRTLITSGTTLATVASVW 252
Cdd:PRK08578 177 ALMNLFGIELSLATVAALLMLIGYSVDSDILLTTRV---LKRRGT--------FDESIKRAMRTGITMTLTTIAAMAVLY 245


                 ....*.
gi 940642111 253 LLAGAP 258
Cdd:PRK08578 246 IVSTIP 251
SecD COG0342
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ...
 114-278 1.04e-07

Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440111 [Multi-domain]  Cd Length: 434  Bit Score: 52.81  E-value: 1.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 114 EVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFewRLA-VGSVVALVhdlllvlglfslfqleFNLTVLASLLA 192
Cdd:COG0342  254 EIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYY--RLPgLVANIALA----------------LNVVLLLGVLS 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 193 IIGYSLN---------------DS-IIVGDRVRELLRvksnNALSPASIINSAIKSTLtRTLITS-GTTLATVASVWLLA 255
Cdd:COG0342  316 LLGATLTlpgiagiiltigmavDAnVLIFERIREELR----AGRSLRAAIEAGFKRAF-STILDAnVTTLIAAVVLFVLG 390

                        170       180
                 ....*....|....*....|...
gi 940642111 256 GAPLQGFAIALFTGIVVGTFSSI 278
Cdd:COG0342  391 TGPVKGFAVTLILGILISMFTAV 413
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 113-294 6.32e-06

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 47.53  E-value: 6.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 113 AEVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVrFEWRLAVGSVVALVHDLLLVLGLFSLFQLEFNLTVLASLLA 192
Cdd:PRK13024 248 LKIIESRSVGPTLGQDAIDAGIIAGIIGFALIFLFMLV-YYGLPGLIANIALLLYIFLTLGALSSLGAVLTLPGIAGLVL 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 193 IIGYSLNDSIIVGDRVRELLR--------VKSNNALSPASIINSAIkstltrtlitsgTTLATVASVWLLAGAPLQGFAI 264
Cdd:PRK13024 327 GIGMAVDANVLIFERIKEELRkgkslkkaFKKGFKNAFSTILDSNI------------TTLIAAAILFFFGTGPVKGFAT 394

                        170       180       190
                 ....*....|....*....|....*....|
gi 940642111 265 ALFTGIVVGTFSSICIAATLPELLGLSAEN 294
Cdd:PRK13024 395 TLIIGILASLFTAVFLTRLLLELLVKRGDK 424
secD PRK05812
preprotein translocase subunit SecD; Reviewed
 121-278 1.13e-04

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 235615 [Multi-domain]  Cd Length: 462  Bit Score: 43.29  E-value: 1.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 121 IGSQVGDELFEQGCLALFSAMVAVMLYLAVRFewRLA-VGSVVALVhdlllvlglfslfqleFNLTVLASLLAIIGYSLN 199
Cdd:PRK05812 287 IGPSLGADSIRAGLIAGLIGLALVLLFMILYY--RLFgLIANIALV----------------ANLVLILAVLSLLGATLT 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111 200 ---------------DS-IIVGDRVRELLRvksnNALSPASIINSAIKSTLtRTLITS-GTTLATVASVWLLAGAPLQGF 262
Cdd:PRK05812 349 lpgiagivltigmavDAnVLIFERIREELR----EGRSLRSAIEAGFKRAF-STILDSnITTLIAAIILYALGTGPVKGF 423

                        170
                 ....*....|....*.
gi 940642111 263 AIALFTGIVVGTFSSI 278
Cdd:PRK05812 424 AVTLGIGILTSMFTAI 439
Sec_GG pfam07549
SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export ...
 33-58 1.35e-03

SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force. This alignment encompasses a -GG- motif typically found in N-terminal half of the SecD/SecF proteins.


Pssm-ID: 462205 [Multi-domain]  Cd Length: 27  Bit Score: 35.34  E-value: 1.35e-03
                          10        20
                  ....*....|....*....|....*.
gi 940642111   33 LSQKGLNFGLDFTGGYLTEFTTSQGV 58
Cdd:pfam07549   2 LFTRGLNLGLDFTGGTVIELQFDQPV 27
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 114-278 3.70e-03

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 39.07  E-value: 3.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  114 EVLSSAYIGSQVGDELFEQGCLALFSAMVAVMLYLAVRFEWRLAVGSVvALVHDLLLVLGLFSLFQLEFNLTVLASLLAI 193
Cdd:PRK12911  892 EVLSEEVISPELGKSQRTQGIISVCLGLAVLIVLMSVYYRFGGVIASG-AVLLNLLLIWAALQYLDAPLTLSGLAGIVLA 970

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940642111  194 IGYSLNDSIIVGDRVRE---LLRVKSNNALSPASIINSAI-KSTLTrtlitsgTTLATvASVWLLAGAPLQGFAIALFTG 269
Cdd:PRK12911  971 MGMAVDANVLVFERIREeylLSRSLSESVEAGYKKAFSAIfDSNLT-------TILAS-ALLLMLDTGPIKGFALTLIIG 1042


                  ....*....
gi 940642111  270 IVVGTFSSI 278
Cdd:PRK12911 1043 IFSSMFTAL 1051
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH