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Conserved domains on  [gi|1124289697|ref|WP_074584275|]
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class II aldolase/adducin family protein [Pseudomonas oryzihabitans]

Protein Classification

class II aldolase/adducin family protein( domain architecture ID 10012869)

class II aldolase/adducin family protein similar to L-fuculose phosphate aldolase, which catalyzes the reversible aldol cleavage of L-fuculose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 3-255 1.03e-133

aldolase II superfamily protein; Provisional


:

Pssm-ID: 235916  Cd Length: 252  Bit Score: 377.27  E-value: 1.03e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697   3 THKNAHPEIAAAEWSMRCELAAFYRLLFHFGMTDIIDTHISVKVPGHEDQFLINRYGMLFSKVTASSLIKINIRGEIIDD 82
Cdd:PRK07044    2 QPAAVPARVSPAEWQARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVDD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  83 RRDigDINQAGFNIHAAVHSARHDAYCVVHTHTDAGIAVSAQEQGLLPISQHALKYYRRLSYHDYEGIALNPDECPRLIE 162
Cdd:PRK07044   82 SPY--PVNPAGFTIHSAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALQFYGRLAYHDYEGIALDLDEGERLVA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697 163 DLGRNMAMVLRNHGLLALGGSVAEAFNQIYFLERACQVQVRALAGGAALRIPSPEVCELTARQCEDEIENQLHELAWQAA 242
Cdd:PRK07044  160 DLGDKPAMLLRNHGLLTVGRTVAEAFLLMYTLERACEIQVAAQAGGGELVLPPPEVAERTARQSLFDPGAGAGELAWPAL 239

                         250
                  ....*....|...
gi 1124289697 243 KRLIETQRADYAS 255
Cdd:PRK07044  240 LRKLDRIDPGYRD 252
 
Name Accession Description Interval E-value
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 3-255 1.03e-133

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 377.27  E-value: 1.03e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697   3 THKNAHPEIAAAEWSMRCELAAFYRLLFHFGMTDIIDTHISVKVPGHEDQFLINRYGMLFSKVTASSLIKINIRGEIIDD 82
Cdd:PRK07044    2 QPAAVPARVSPAEWQARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVDD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  83 RRDigDINQAGFNIHAAVHSARHDAYCVVHTHTDAGIAVSAQEQGLLPISQHALKYYRRLSYHDYEGIALNPDECPRLIE 162
Cdd:PRK07044   82 SPY--PVNPAGFTIHSAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALQFYGRLAYHDYEGIALDLDEGERLVA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697 163 DLGRNMAMVLRNHGLLALGGSVAEAFNQIYFLERACQVQVRALAGGAALRIPSPEVCELTARQCEDEIENQLHELAWQAA 242
Cdd:PRK07044  160 DLGDKPAMLLRNHGLLTVGRTVAEAFLLMYTLERACEIQVAAQAGGGELVLPPPEVAERTARQSLFDPGAGAGELAWPAL 239

                         250
                  ....*....|...
gi 1124289697 243 KRLIETQRADYAS 255
Cdd:PRK07044  240 LRKLDRIDPGYRD 252
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 13-225 9.70e-65

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 200.44  E-value: 9.70e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  13 AAEWSMRCELAAFYRLLFHFGMTDIIDTHISVKVPghEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRRDigdiNQA 92
Cdd:COG0235     1 MEEEELREELAAAGRRLARRGLVDGTAGNISVRLD--DDRFLITPSGVDFGELTPEDLVVVDLDGNVVEGDLK----PSS 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  93 GFNIHAAVHSARHDAYCVVHTHTDAGIAVSAQEQGLLPISQ-HALKYYRRLSYHDYEGIAlNPDECPRLIEDLGRNMAMV 171
Cdd:COG0235    75 ETPLHLAIYRARPDVGAVVHTHSPYATALSALGEPLPPLEQtEAAAFLGDVPVVPYAGPG-TEELAEAIAEALGDRPAVL 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1124289697 172 LRNHGLLALGGSVAEAFNQIYFLERACQVQVRALAGGAALRIPsPEVCELTARQ 225
Cdd:COG0235   154 LRNHGVVVWGKDLAEAFDRAEVLEEAARIQLLALALGGPLVLS-DEEIDKLARK 206
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 20-202 8.79e-52

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 166.57  E-value: 8.79e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  20 CELAAFYRLLFHFGMTDIIDTHISVKVPghEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRRDIgdinQAGFNIHAA 99
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRLP--GDGFLITPSGVDFGELTPEDLVVVDLDGNVVEGGLKP----SSETPLHLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697 100 VHSARHDAYCVVHTHTDAGIAVSAQEQGLLPISQHALKY-YRRLSYHDYEGIAlNPDECPRLIEDLGRNM-AMVLRNHGL 177
Cdd:pfam00596  75 IYRARPDAGAVVHTHSPYATALSLAKEGLPPITQEAADFlGGDIPIIPYYTPG-TEELGERIAEALGGDRkAVLLRNHGL 153

                         170       180
                  ....*....|....*....|....*
gi 1124289697 178 LALGGSVAEAFNQIYFLERACQVQV 202
Cdd:pfam00596 154 LVWGKTLEEAFYLAEELERAAEIQL 178
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 22-202 5.99e-51

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 164.73  E-value: 5.99e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697   22 LAAFYRLLFHFGMTDIIDTHISVKVpGHEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRRdiGDINQAGFNIHAAVH 101
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARV-GEEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGG--GPKPSSETPLHLAIY 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  102 SARHDAYCVVHTHTDAGIAVSAQ--EQGLLPISQHALKYYRRLSYHDYEGIAL-NPDECPRLIEDLGRNM----AMVLRN 174
Cdd:smart01007  78 RARPDVGAVVHTHSPYATALAALgkPLPLLPTEQAAAFLGGEIPYAPYAGPGTeLAEEGAELAEALAEALpdrpAVLLRN 157

                          170       180
                   ....*....|....*....|....*...
gi 1124289697  175 HGLLALGGSVAEAFNQIYFLERACQVQV 202
Cdd:smart01007 158 HGLLVWGKTLEEAFDLAEELEEAAEIQL 185
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 15-220 9.11e-34

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 121.32  E-value: 9.11e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  15 EWSMRcELAAFYRLLFHFGMTDIIDTHISVKVPgHEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRRDIGDinqagF 94
Cdd:cd00398     1 EKLKR-KIIAACLLLDLYGWVTGTGGNVSARDR-DRGYFLITPSGVDYEEMTASDLVVVDAQGKVVEGKKPSSE-----T 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  95 NIHAAVHSARHDAYCVVHTHTDAGIAVSAQEQGLLPIS--QHALKYYRRLSYHDYEGIALNPDEcprLIEDLGRNM---- 168
Cdd:cd00398    74 PLHLALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGhtACAVYFTGDIPCTPYMTPETGEDE---IGTQRALGFpnsk 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1124289697 169 AMVLRNHGLLALGGSVAEAFNQIYFLERACQVQVRALAGGAALRIPSPEVCE 220
Cdd:cd00398   151 AVLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGQLPPISLELLN 202
 
Name Accession Description Interval E-value
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 3-255 1.03e-133

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 377.27  E-value: 1.03e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697   3 THKNAHPEIAAAEWSMRCELAAFYRLLFHFGMTDIIDTHISVKVPGHEDQFLINRYGMLFSKVTASSLIKINIRGEIIDD 82
Cdd:PRK07044    2 QPAAVPARVSPAEWQARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVDD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  83 RRDigDINQAGFNIHAAVHSARHDAYCVVHTHTDAGIAVSAQEQGLLPISQHALKYYRRLSYHDYEGIALNPDECPRLIE 162
Cdd:PRK07044   82 SPY--PVNPAGFTIHSAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALQFYGRLAYHDYEGIALDLDEGERLVA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697 163 DLGRNMAMVLRNHGLLALGGSVAEAFNQIYFLERACQVQVRALAGGAALRIPSPEVCELTARQCEDEIENQLHELAWQAA 242
Cdd:PRK07044  160 DLGDKPAMLLRNHGLLTVGRTVAEAFLLMYTLERACEIQVAAQAGGGELVLPPPEVAERTARQSLFDPGAGAGELAWPAL 239

                         250
                  ....*....|...
gi 1124289697 243 KRLIETQRADYAS 255
Cdd:PRK07044  240 LRKLDRIDPGYRD 252
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 13-225 9.70e-65

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 200.44  E-value: 9.70e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  13 AAEWSMRCELAAFYRLLFHFGMTDIIDTHISVKVPghEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRRDigdiNQA 92
Cdd:COG0235     1 MEEEELREELAAAGRRLARRGLVDGTAGNISVRLD--DDRFLITPSGVDFGELTPEDLVVVDLDGNVVEGDLK----PSS 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  93 GFNIHAAVHSARHDAYCVVHTHTDAGIAVSAQEQGLLPISQ-HALKYYRRLSYHDYEGIAlNPDECPRLIEDLGRNMAMV 171
Cdd:COG0235    75 ETPLHLAIYRARPDVGAVVHTHSPYATALSALGEPLPPLEQtEAAAFLGDVPVVPYAGPG-TEELAEAIAEALGDRPAVL 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1124289697 172 LRNHGLLALGGSVAEAFNQIYFLERACQVQVRALAGGAALRIPsPEVCELTARQ 225
Cdd:COG0235   154 LRNHGVVVWGKDLAEAFDRAEVLEEAARIQLLALALGGPLVLS-DEEIDKLARK 206
PRK06661 PRK06661
hypothetical protein; Provisional
 21-247 5.38e-59

hypothetical protein; Provisional


Pssm-ID: 168637  Cd Length: 231  Bit Score: 186.96  E-value: 5.38e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  21 ELAAFYRLLFHFGMTDIIDTHISVKvPGHEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRRDIgdINQAGFNIHAAV 100
Cdd:PRK06661    6 NLAAAYRIMAYLSLDDHTYTHLSAR-PKNADFYYIYPFGLRFEEVTTENLLKVSLDGQILEGEEYQ--YNKTGYFIHGSI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697 101 HSARHDAYCVVHTHTDAGIAVSAQEQGLLPISQHALKYYRRLSYHDYEGIALNPD-ECPRLIEDLGRNMAMVLRNHGLLA 179
Cdd:PRK06661   83 YKTRPDISAIFHYHTPASIAVSALKCGLLPISQWALHFYDRISYHNYNSLALDADkQSSRLVNDLKQNYVMLLRNHGAIT 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1124289697 180 LGGSVAEAFNQIYFLERACQVQVRALA-GGAALRIPSPEVCElTARQCEDEIENQLHELAWQAAKRLIE 247
Cdd:PRK06661  163 CGKTIHEAMFYTYHLEQACKTQCLLNStKKQELIIPSVEICK-KTVKDLLSFEEDLGKRDWAAWLRLIK 230
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 20-202 8.79e-52

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 166.57  E-value: 8.79e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  20 CELAAFYRLLFHFGMTDIIDTHISVKVPghEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRRDIgdinQAGFNIHAA 99
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRLP--GDGFLITPSGVDFGELTPEDLVVVDLDGNVVEGGLKP----SSETPLHLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697 100 VHSARHDAYCVVHTHTDAGIAVSAQEQGLLPISQHALKY-YRRLSYHDYEGIAlNPDECPRLIEDLGRNM-AMVLRNHGL 177
Cdd:pfam00596  75 IYRARPDAGAVVHTHSPYATALSLAKEGLPPITQEAADFlGGDIPIIPYYTPG-TEELGERIAEALGGDRkAVLLRNHGL 153

                         170       180
                  ....*....|....*....|....*
gi 1124289697 178 LALGGSVAEAFNQIYFLERACQVQV 202
Cdd:pfam00596 154 LVWGKTLEEAFYLAEELERAAEIQL 178
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 22-202 5.99e-51

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 164.73  E-value: 5.99e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697   22 LAAFYRLLFHFGMTDIIDTHISVKVpGHEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRRdiGDINQAGFNIHAAVH 101
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARV-GEEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGG--GPKPSSETPLHLAIY 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  102 SARHDAYCVVHTHTDAGIAVSAQ--EQGLLPISQHALKYYRRLSYHDYEGIAL-NPDECPRLIEDLGRNM----AMVLRN 174
Cdd:smart01007  78 RARPDVGAVVHTHSPYATALAALgkPLPLLPTEQAAAFLGGEIPYAPYAGPGTeLAEEGAELAEALAEALpdrpAVLLRN 157

                          170       180
                   ....*....|....*....|....*...
gi 1124289697  175 HGLLALGGSVAEAFNQIYFLERACQVQV 202
Cdd:smart01007 158 HGLLVWGKTLEEAFDLAEELEEAAEIQL 185
PRK06486 PRK06486
aldolase;
12-255 2.55e-50

aldolase;


Pssm-ID: 235814  Cd Length: 262  Bit Score: 165.66  E-value: 2.55e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  12 AAAEWSMRCELAAFYRLLFHFGMTDIIDTHISVKVPGHEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRrdiGDINQ 91
Cdd:PRK06486   21 SDAVAQARVDLAACFRAAARHGLEEGICNHFSAVLPGHDDLFLVNPYGYAFSEITASDLLICDFDGNVLAGR---GEPEA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  92 AGFNIHAAVHSARHDAYCVVHTHTDAGIAVSAQE-QGLLPISQHALKYYRRLSY-HDYEGIALNPDECPRLIEDLGRNMA 169
Cdd:PRK06486   98 TAFFIHARIHRAIPRAKAAFHTHMPYATALSLTEgRPLTTLGQTALKFYGRTAVdEDYNGLALDAAEGDRIARAMGDADI 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697 170 MVLRNHGLLALGGSVAEAFNQIYFLERACQVQVRALAGGAALRIPSPEVCELTARQCEdEIENQLHELAWQAAKRLIETQ 249
Cdd:PRK06486  178 VFLKNHGVMVCGPRIAEAWDDLYYLERACEVQVLAMSTGRPLVPVDPAIAAAVARQMR-EGDRESARLHLEALRRTLDRE 256


                  ....*.
gi 1124289697 250 RADYAS 255
Cdd:PRK06486  257 EPAYRT 262
PRK06208 PRK06208
class II aldolase/adducin family protein;
22-225 9.95e-47

class II aldolase/adducin family protein;


Pssm-ID: 235743  Cd Length: 274  Bit Score: 156.69  E-value: 9.95e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  22 LAAFYRLLFHFGMTDIIDTHISVKVPGHEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRRDIgdiNQAGFNIHAAVH 101
Cdd:PRK06208   47 LAAAFRLFARFGFDEGLAGHITARDPELPDHFWVNPLGVHFSQIKVSDLLLVDHDGEVVEGDRPL---NRAAFAIHSAIH 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697 102 SARHDAYCVVHTHTDAGIAVSAQEQGLLPISQHALKYYRRLS-YHDYEGIALNPDECPRLIEDLGRNMAMVLRNHGLLAL 180
Cdd:PRK06208  124 EARPDVVAAAHTHSTYGKAWSTLGRPLDPITQDACAFYEDHAlFDDFTGVVVDTSEGRRIAAALGTHKAVILQNHGLLTV 203

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1124289697 181 GGSV-AEAFNQIYfLERACQVQVRALAGGaALRIPSPEVCELTARQ 225
Cdd:PRK06208  204 GPSVdAAAWWFIA-LERACQTQLLAEAAG-PPQPIDHETARHTRSQ 247
PRK07490 PRK07490
hypothetical protein; Provisional
 14-255 2.68e-45

hypothetical protein; Provisional


Pssm-ID: 236031 [Multi-domain]  Cd Length: 245  Bit Score: 152.18  E-value: 2.68e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  14 AEWSMRCELAAFYRLLFHFGMTDIIDTHISVKVPGHEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRRDIGDINQAG 93
Cdd:PRK07490    7 DEEQIRVDLAAAFRWIARLGMHEAVANHFSAAVSADGKQFLLNPKWKHFSRIRASDLLLLDADDPSTAERPDVPDATAWA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  94 fnIHAAVHSARHDAYCVVHTHTDAGIAVSAQEQG-LLPISQHALKYYRRLSYHD-YEGIALNpDECPRLIEDLGRNMAMV 171
Cdd:PRK07490   87 --IHGQIHRRLPHARCVMHVHSVYATALACLADPtLPPIDQNTARFFNRVAVDTlYGGMALE-EEGERLAGLLGDKRRLL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697 172 LRNHGLLALGGSVAEAFNQIYFLERACQVQVRALAGGAALRIPSPEVCELTARQCEDEIENQLHELAwqAAKRLIETQRA 251
Cdd:PRK07490  164 MGNHGVLVTGDTVAEAFDDLYYFERACQTYITALSTGQPLRVLSDAVAEKTARDWEDYPGFSRQHFA--ELKALLDEEDP 241


                  ....
gi 1124289697 252 DYAS 255
Cdd:PRK07490  242 SYAD 245
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 15-220 9.11e-34

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 121.32  E-value: 9.11e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  15 EWSMRcELAAFYRLLFHFGMTDIIDTHISVKVPgHEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRRDIGDinqagF 94
Cdd:cd00398     1 EKLKR-KIIAACLLLDLYGWVTGTGGNVSARDR-DRGYFLITPSGVDYEEMTASDLVVVDAQGKVVEGKKPSSE-----T 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  95 NIHAAVHSARHDAYCVVHTHTDAGIAVSAQEQGLLPIS--QHALKYYRRLSYHDYEGIALNPDEcprLIEDLGRNM---- 168
Cdd:cd00398    74 PLHLALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGhtACAVYFTGDIPCTPYMTPETGEDE---IGTQRALGFpnsk 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1124289697 169 AMVLRNHGLLALGGSVAEAFNQIYFLERACQVQVRALAGGAALRIPSPEVCE 220
Cdd:cd00398   151 AVLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGQLPPISLELLN 202
PRK07090 PRK07090
class II aldolase/adducin domain protein; Provisional
 1-214 2.73e-15

class II aldolase/adducin domain protein; Provisional


Pssm-ID: 180832  Cd Length: 260  Bit Score: 73.13  E-value: 2.73e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697   1 MQTHknahpeIAAAEWSMRCELAAFYRLLFHFGMTDIIDTHISVK--VPGhedQFLINRYGMLFSKVTASSLIKINIRGE 78
Cdd:PRK07090   20 MDNE------LKDSGWTLRQKLALTCRILFDAGHDSGLAGQITARaeAPG---TYYTQRLGLGFDEITASNLLLVDEDLN 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  79 IIDDRrdiGDINQAGfNIHAAVHSARHDAYCVVHTHTDAGIAVSAQEQGLLpISQHAL-KYYRRLSY-HDYEGIALNPDE 156
Cdd:PRK07090   91 VLDGE---GMPNPAN-RFHSWIYRARPDVNCIIHTHPPHVAALSMLEVPLV-VSHMDTcPLYDDCAFlKDWPGVPVGNEE 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1124289697 157 CPRLIEDLGRNMAMVLRNHGLLALGGSVAEAFNQIYFLERACQVQVRALAGGAALRIP 214
Cdd:PRK07090  166 GEIISAALGDKRAILLSHHGQLVAGKSIEEACVLALLIERAARLQLLAMAAGPIKPIP 223
PRK06557 PRK06557
L-ribulose-5-phosphate 4-epimerase; Validated
 9-224 2.88e-06

L-ribulose-5-phosphate 4-epimerase; Validated


Pssm-ID: 235829 [Multi-domain]  Cd Length: 221  Bit Score: 46.92  E-value: 2.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697   9 PEIAAAEWSMRCELAAFYRLLFHFGMTDIIDTHISVKVPGhEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRRDIGD 88
Cdd:PRK06557    2 PEVRAMVEKLREEVCKLHLELPKYGLVVWTSGNVSARDPG-TDLVVIKPSGVSYDDLTPEDMVVVDLDGNVVEGDLKPSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  89 INQAgfniHAAVHSARHDAYCVVHTHTDAGIAVSAQEQ--------------GLLPISQHALkyyrrlsyhdyegiaLNP 154
Cdd:PRK06557   81 DTAS----HLYVYRHMPDVGGVVHTHSTYATAWAARGEpipcvltamadefgGPIPVGPFAL---------------IGD 141

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1124289697 155 DECPR-LIEDL--GRNMAMVLRNHGLLALGGSVAEAFNQIYFLERACQVQVRALAGGAALRIPSPEVCELTAR 224
Cdd:PRK06557  142 EAIGKgIVETLkgGRSPAVLMQNHGVFTIGKDAEDAVKAAVMVEEVARTVHIARQLGEPIPIPQEEIDRLYDR 214
PRK08333 PRK08333
aldolase;
21-188 8.19e-06

aldolase;


Pssm-ID: 181393 [Multi-domain]  Cd Length: 184  Bit Score: 45.20  E-value: 8.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  21 ELAAFYRLLFHFGMTDIIDTHISVKVpghEDQFLINRYGMLFSKVTASSLIKINIRGEIIDDRRDigdinQAGFNIHAAV 100
Cdd:PRK08333    7 QLVKYSKLAHERGLTAAFGGNLSIRV---GNLVFIKATGSVMDELTREQVAVIDLNGNQLSSVRP-----SSEYRLHLAV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697 101 HSARHDAYCVVHTHTDAGIAVSAQEQGLLP-ISQHALKYYRRLSYhdyegIALNPDECPRLIEDLGRNM----AMVLRNH 175
Cdd:PRK08333   79 YRNRPDVRAIAHLHPPYSIVASTLLEEELPiITPEAELYLKKIPI-----LPFRPAGSVELAEQVAEAMkeydAVIMERH 153

                         170
                  ....*....|...
gi 1124289697 176 GLLALGGSVAEAF 188
Cdd:PRK08333  154 GIVTVGRSLREAF 166
PRK08660 PRK08660
aldolase;
21-200 1.82e-04

aldolase;


Pssm-ID: 181527 [Multi-domain]  Cd Length: 181  Bit Score: 41.10  E-value: 1.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  21 ELAAFYRLLF-------HFGmtdiidtHISVKVpghEDQFLINRYGMLFSKVTASSLIKINIRGeiiDDRRDIGDINQAG 93
Cdd:PRK08660    4 EFARIGKKLFahglvssHFG-------NISVRT---GDGLLITRTGSMLDEITEGDVIEVGIDD---DGSVDPLASSETP 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  94 fnIHAAVHsARHDAYCVVHTHTDAGIAVSAQEQGLLPIsqhalkyyrrlsyhDYEGIALNPdECPRLIEDLG-RNMA--- 169
Cdd:PRK08660   71 --VHRAIY-RRTSAKAIVHAHPPYAVALSLLEDEIVPL--------------DSEGLYFLG-TIPVVGGDIGsGELAenv 132

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1124289697 170 ---------MVLRNHGLLALGGSVAEAFNQIYFLERACQV 200
Cdd:PRK08660  133 aralsehkgVVVRGHGTFAIGKTLEEAYIYTSQLEHSCKV 172
PRK08087 PRK08087
L-fuculose-phosphate aldolase;
42-187 3.53e-03

L-fuculose-phosphate aldolase;


Pssm-ID: 181226 [Multi-domain]  Cd Length: 215  Bit Score: 37.80  E-value: 3.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697  42 ISVKvpgHEDQFLINRYGMLFSKVTASSLIKINIRGeiiddRRDIGDINQAGFNIHAAVHSARHDAYCVVHTHTDAGIAV 121
Cdd:PRK08087   30 VSVR---YQDGMLITPTGIPYEKLTESHIVFVDGNG-----KHEEGKLPSSEWRFHMAAYQTRPDANAVVHNHAVHCTAV 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124289697 122 SAQEQGL--------------LPISQHALKYYRRLSYHDYEGIAlnpdecprliedlgRNMAMVLRNHGLLALGGSVAEA 187
Cdd:PRK08087  102 SILNRPIpaihymiaaaggnsIPCAPYATFGTRELSEHVALALK--------------NRKATLLQHHGLIACEVNLEKA 167
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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