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Conserved domains on  [gi|1151113182|ref|WP_078085474|]
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CpsD/CapB family tyrosine-protein kinase [Microbulbifer mangrovi]

Protein Classification

CpsD/CapB family tyrosine-protein kinase( domain architecture ID 12941857)

CpsD/CapB family tyrosine-protein kinase is an autophosphorylating protein-tyrosine kinase that may be involved in the regulation of capsular polysaccharide biosynthesis

CATH:  3.40.50.300
EC:  2.7.10.2
Gene Ontology:  GO:0005524|GO:0004715|GO:0004713
PubMed:  22889913|19525115
SCOP:  4003987

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BY-kinase cd05387
bacterial tyrosine-kinase; Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on ...
 76-264 2.54e-42

bacterial tyrosine-kinase; Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.


:

Pssm-ID: 349772 [Multi-domain]  Cd Length: 190  Bit Score: 143.48  E-value: 2.54e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  76 FDRLRTHVLNRMSLKGWRTLAIVSPAPGAGKSVVAINLAMSIAQLpTRRALLVDLDLRCPSVLRYLGVGADNSLNDFLED 155
Cdd:cd05387     3 FRTLRTNLLFAGSDAGPKVIAVTSASPGEGKSTVAANLAVALAQS-GKRVLLIDADLRRPSLHRLLGLPNEPGLSEVLSG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 156 KCSFEETLLKPQLPRLSVTGASRRIENSTEQLASRKIQDVVSSTRSNigDGVVIFDLPPVLFSDDAISILPKIDCALLVL 235
Cdd:cd05387    82 QASLEDVIQSTNIPNLDVLPAGTVPPNPSELLSSPRFAELLEELKEQ--YDYVIIDTPPVLAVADALILAPLVDGVLLVV 159

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1151113182 236 PDGGYTEQELDDFLQ--QTPETNLVGTVLNK 264
Cdd:cd05387   160 RAGKTRRREVKEALErlEQAGAKVLGVVLNK 190
 
Name Accession Description Interval E-value
BY-kinase cd05387
bacterial tyrosine-kinase; Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on ...
 76-264 2.54e-42

bacterial tyrosine-kinase; Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.


Pssm-ID: 349772 [Multi-domain]  Cd Length: 190  Bit Score: 143.48  E-value: 2.54e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  76 FDRLRTHVLNRMSLKGWRTLAIVSPAPGAGKSVVAINLAMSIAQLpTRRALLVDLDLRCPSVLRYLGVGADNSLNDFLED 155
Cdd:cd05387     3 FRTLRTNLLFAGSDAGPKVIAVTSASPGEGKSTVAANLAVALAQS-GKRVLLIDADLRRPSLHRLLGLPNEPGLSEVLSG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 156 KCSFEETLLKPQLPRLSVTGASRRIENSTEQLASRKIQDVVSSTRSNigDGVVIFDLPPVLFSDDAISILPKIDCALLVL 235
Cdd:cd05387    82 QASLEDVIQSTNIPNLDVLPAGTVPPNPSELLSSPRFAELLEELKEQ--YDYVIIDTPPVLAVADALILAPLVDGVLLVV 159

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1151113182 236 PDGGYTEQELDDFLQ--QTPETNLVGTVLNK 264
Cdd:cd05387   160 RAGKTRRREVKEALErlEQAGAKVLGVVLNK 190
Mrp COG0489
Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, ...
 74-276 1.31e-36

Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440255 [Multi-domain]  Cd Length: 289  Bit Score: 131.46  E-value: 1.31e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  74 GVFDRLRTHVLNRMSLKGWRTLAIVSPAPGAGKSVVAINLAMSIAQLpTRRALLVDLDLRCPSVLRYLGVGADNSLNDFL 153
Cdd:COG0489    74 LLALALLLLLLLLLLRLLLEVIAVTSGKGGEGKSTVAANLALALAQS-GKRVLLIDADLRGPSLHRMLGLENRPGLSDVL 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 154 EDKCSFEETLLKPQLPRLSVTGASRRIENSTEQLASRKIQDVVSSTRSNIgDgVVIFDLPPVLFSDDAISILPKIDCALL 233
Cdd:COG0489   153 AGEASLEDVIQPTEVEGLDVLPAGPLPPNPSELLASKRLKQLLEELRGRY-D-YVIIDTPPGLGVADATLLASLVDGVLL 230

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1151113182 234 VLPDGGYTEQELD---DFLQQTpETNLVGTVLNKVADEKEYAPYGY 276
Cdd:COG0489   231 VVRPGKTALDDVRkalEMLEKA-GVPVLGVVLNMVCPKGERYYGGG 275
eps_transp_fam TIGR01005
exopolysaccharide transport protein family; The model describes the exopolysaccharide ...
 76-276 7.88e-22

exopolysaccharide transport protein family; The model describes the exopolysaccharide transport protein family in bacteria. The transport protein is part of a large genetic locus which is associated with exopolysaccharide (EPS) biosynthesis. Detailed molecular characterization and gene fusion analysis revealed atleast seven gene products are involved in the overall regulation, which among other things, include exopolysaccharide biosynthesis, property of conferring virulence and exopolysaccharide export. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273391 [Multi-domain]  Cd Length: 764  Bit Score: 94.79  E-value: 7.88e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  76 FDRLRTHVLNRMSLKGWRTLAIVSPAPGAGKSVVAINLAMSIAQlPTRRALLVDLDLRCPSVLRYLGVGADNSLNDFLED 155
Cdd:TIGR01005 537 FRNAKLACDFALADAENNLIAIAGALPDEGKSFIAANFAALIAA-GGKRTLLIDADIRKGGLHQMFGKAPKPGLLDLLAG 615

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 156 KCSFEETLLKPQLPRLSVT---GASRRIENSTEQLASRKIQDVVSSTRSNIgdGVVIFDLPPVLFSDDAISILPKIDCAL 232
Cdd:TIGR01005 616 EASIEAGIHRDQRPGLAFIaagGASHFPHNPNELLANPAMAELIDNARNAF--DLVLVDLAALAAVADAAAFAALADGIL 693

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1151113182 233 LVLPDGGYTEQELDDFLQQTPETN--LVGTVLNKVaDEKEYAPYGY 276
Cdd:TIGR01005 694 FVTEFERSPLGEIRDLIHQEPHANsdVLGVIFNAL-DMNELGKYGD 738
PRK09841 PRK09841
tyrosine-protein kinase;
79-276 1.25e-10

tyrosine-protein kinase;


Pssm-ID: 182106 [Multi-domain]  Cd Length: 726  Bit Score: 61.46  E-value: 1.25e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  79 LRTHVLNRMSLKGWRTLAIVSPAPGAGKSVVAINLAMSIAQlPTRRALLVDLDLRCPSVLRYLGVGADNSLNDFLEDKCS 158
Cdd:PRK09841  518 LRTSLHFAMMETENNILMITGATPDSGKTFVSSTLAAVIAQ-SDQKVLFIDADLRRGYSHNLFTVSNEHGLSEYLAGKDE 596

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 159 FEETLLKPQLPRLSVTGASRRIENSTEQLASRKIQDVVssTRSNIGDGVVIFDLPPVLFSDDAISILPKIDCALLVLPDG 238
Cdd:PRK09841  597 LNKVIQHFGKGGFDVITRGQVPPNPSELLMRDRMRQLL--EWANDHYDLVIVDTPPMLAVSDAAVVGRSVGTSLLVARFG 674

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1151113182 239 GYTEQELDDFLQQTPET--NLVGTVLNKVADEKE-YAPYGY 276
Cdd:PRK09841  675 LNTAKEVSLSMQRLEQAgvNIKGAILNGVIKRAStAYSYGY 715
ParA pfam10609
NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid ...
 93-143 6.75e-04

NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.


Pssm-ID: 431392 [Multi-domain]  Cd Length: 246  Bit Score: 40.13  E-value: 6.75e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1151113182  93 RTLAIVSPAPGAGKSVVAINLAMSIAQLPTRRALLvDLDLRCPSVLRYLGV 143
Cdd:pfam10609   4 HVIAVASGKGGVGKSTVAVNLALALARLGYKVGLL-DADIYGPSIPRMLGL 53
 
Name Accession Description Interval E-value
BY-kinase cd05387
bacterial tyrosine-kinase; Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on ...
 76-264 2.54e-42

bacterial tyrosine-kinase; Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.


Pssm-ID: 349772 [Multi-domain]  Cd Length: 190  Bit Score: 143.48  E-value: 2.54e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  76 FDRLRTHVLNRMSLKGWRTLAIVSPAPGAGKSVVAINLAMSIAQLpTRRALLVDLDLRCPSVLRYLGVGADNSLNDFLED 155
Cdd:cd05387     3 FRTLRTNLLFAGSDAGPKVIAVTSASPGEGKSTVAANLAVALAQS-GKRVLLIDADLRRPSLHRLLGLPNEPGLSEVLSG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 156 KCSFEETLLKPQLPRLSVTGASRRIENSTEQLASRKIQDVVSSTRSNigDGVVIFDLPPVLFSDDAISILPKIDCALLVL 235
Cdd:cd05387    82 QASLEDVIQSTNIPNLDVLPAGTVPPNPSELLSSPRFAELLEELKEQ--YDYVIIDTPPVLAVADALILAPLVDGVLLVV 159

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1151113182 236 PDGGYTEQELDDFLQ--QTPETNLVGTVLNK 264
Cdd:cd05387   160 RAGKTRRREVKEALErlEQAGAKVLGVVLNK 190
Mrp COG0489
Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, ...
 74-276 1.31e-36

Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440255 [Multi-domain]  Cd Length: 289  Bit Score: 131.46  E-value: 1.31e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  74 GVFDRLRTHVLNRMSLKGWRTLAIVSPAPGAGKSVVAINLAMSIAQLpTRRALLVDLDLRCPSVLRYLGVGADNSLNDFL 153
Cdd:COG0489    74 LLALALLLLLLLLLLRLLLEVIAVTSGKGGEGKSTVAANLALALAQS-GKRVLLIDADLRGPSLHRMLGLENRPGLSDVL 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 154 EDKCSFEETLLKPQLPRLSVTGASRRIENSTEQLASRKIQDVVSSTRSNIgDgVVIFDLPPVLFSDDAISILPKIDCALL 233
Cdd:COG0489   153 AGEASLEDVIQPTEVEGLDVLPAGPLPPNPSELLASKRLKQLLEELRGRY-D-YVIIDTPPGLGVADATLLASLVDGVLL 230

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1151113182 234 VLPDGGYTEQELD---DFLQQTpETNLVGTVLNKVADEKEYAPYGY 276
Cdd:COG0489   231 VVRPGKTALDDVRkalEMLEKA-GVPVLGVVLNMVCPKGERYYGGG 275
eps_transp_fam TIGR01005
exopolysaccharide transport protein family; The model describes the exopolysaccharide ...
 76-276 7.88e-22

exopolysaccharide transport protein family; The model describes the exopolysaccharide transport protein family in bacteria. The transport protein is part of a large genetic locus which is associated with exopolysaccharide (EPS) biosynthesis. Detailed molecular characterization and gene fusion analysis revealed atleast seven gene products are involved in the overall regulation, which among other things, include exopolysaccharide biosynthesis, property of conferring virulence and exopolysaccharide export. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273391 [Multi-domain]  Cd Length: 764  Bit Score: 94.79  E-value: 7.88e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  76 FDRLRTHVLNRMSLKGWRTLAIVSPAPGAGKSVVAINLAMSIAQlPTRRALLVDLDLRCPSVLRYLGVGADNSLNDFLED 155
Cdd:TIGR01005 537 FRNAKLACDFALADAENNLIAIAGALPDEGKSFIAANFAALIAA-GGKRTLLIDADIRKGGLHQMFGKAPKPGLLDLLAG 615

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 156 KCSFEETLLKPQLPRLSVT---GASRRIENSTEQLASRKIQDVVSSTRSNIgdGVVIFDLPPVLFSDDAISILPKIDCAL 232
Cdd:TIGR01005 616 EASIEAGIHRDQRPGLAFIaagGASHFPHNPNELLANPAMAELIDNARNAF--DLVLVDLAALAAVADAAAFAALADGIL 693

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1151113182 233 LVLPDGGYTEQELDDFLQQTPETN--LVGTVLNKVaDEKEYAPYGY 276
Cdd:TIGR01005 694 FVTEFERSPLGEIRDLIHQEPHANsdVLGVIFNAL-DMNELGKYGD 738
eps_fam TIGR01007
capsular exopolysaccharide family; This model describes the capsular exopolysaccharide ...
 76-276 1.28e-17

capsular exopolysaccharide family; This model describes the capsular exopolysaccharide proteins in bacteria. The exopolysaccharide gene cluster consists of several genes which encode a number of proteins which regulate the exoploysaccharide biosynthesis(EPS). Atleast 13 genes espA to espM in streptococcus species seem to direct the EPS proteins and all of which share high homology. Functional roles were characterized by gene disruption experiments which resulted in exopolysaccharide-deficient phenotypes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273392 [Multi-domain]  Cd Length: 204  Bit Score: 79.02  E-value: 1.28e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  76 FDRLRTHVlnRMSLKGWRTLAIVSPAPGAGKSVVAINLAMSIAQlPTRRALLVDLDLRCPSVLRYLGV-GADNSLNDFLE 154
Cdd:TIGR01007   3 YNAIRTNI--QFSGAEIKVLLITSVKPGEGKSTTSANIAIAFAQ-AGYKTLLIDGDMRNSVMSGTFKSqNKITGLTNFLS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 155 DKCSFEETLLKPQLPRLSVTGASRRIENSTEQLASRKIQDVVSSTRsNIGDgVVIFDLPPVLFSDDAISILPKIDCALLV 234
Cdd:TIGR01007  80 GTTDLSDAICDTNIENLDVITAGPVPPNPTELLQSSNFKTLIETLR-KRFD-YIIIDTPPIGTVTDAAIIARACDASILV 157

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1151113182 235 LPDGGYTEQELDDFLQQTPET--NLVGTVLNKV-ADEKEYAPYGY 276
Cdd:TIGR01007 158 TDAGKIKKREVKKAKEQLEQAgsNFLGVVLNKVdISVSKYGYYGY 202
CpaE COG4963
Flp pilus assembly ATPase CpaE/TadZ, contains N-terminal REC/TadZ_N domain [Intracellular ...
 7-265 3.99e-13

Flp pilus assembly ATPase CpaE/TadZ, contains N-terminal REC/TadZ_N domain [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443989 [Multi-domain]  Cd Length: 358  Bit Score: 68.60  E-value: 3.99e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182   7 ALDKTRALKTLQSETTGADRVIVSELQPLRGTERLALNDKELEPILLDPAHLEkncifahskSNELCGVFDRLRTHVLNR 86
Cdd:COG4963    30 AEDRRLALAAVAVASGGAAAAAAAYLSAPTPNLILLEALSESAALLADVLPLS---------PDELRAALARLLDPGAAR 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  87 MSlkgwRTLAIVSPAPGAGKSVVAINLAMSIAQLPTRRALLVDLDLRCPSVLRYLGVGADNSLNDFLEDKCSFEETLLKP 166
Cdd:COG4963   101 RG----RVIAVVGAKGGVGATTLAVNLAWALARESGRRVLLVDLDLQFGDVALYLDLEPRRGLADALRNPDRLDETLLDR 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 167 QLPR----LSVTGASRRIENStEQLASRKIQDVVSSTRSNIgdGVVIFDLPPVlFSDDAISILPKIDCALLVlpdggyTE 242
Cdd:COG4963   177 ALTRhssgLSVLAAPADLERA-EEVSPEAVERLLDLLRRHF--DYVVVDLPRG-LNPWTLAALEAADEVVLV------TE 246

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1151113182 243 QE----------LDDFLQQTPETNLVGTVLNKV 265
Cdd:COG4963   247 PDlpslrnakrlLDLLRELGLPDDKVRLVLNRV 279
PRK09841 PRK09841
tyrosine-protein kinase;
79-276 1.25e-10

tyrosine-protein kinase;


Pssm-ID: 182106 [Multi-domain]  Cd Length: 726  Bit Score: 61.46  E-value: 1.25e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  79 LRTHVLNRMSLKGWRTLAIVSPAPGAGKSVVAINLAMSIAQlPTRRALLVDLDLRCPSVLRYLGVGADNSLNDFLEDKCS 158
Cdd:PRK09841  518 LRTSLHFAMMETENNILMITGATPDSGKTFVSSTLAAVIAQ-SDQKVLFIDADLRRGYSHNLFTVSNEHGLSEYLAGKDE 596

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 159 FEETLLKPQLPRLSVTGASRRIENSTEQLASRKIQDVVssTRSNIGDGVVIFDLPPVLFSDDAISILPKIDCALLVLPDG 238
Cdd:PRK09841  597 LNKVIQHFGKGGFDVITRGQVPPNPSELLMRDRMRQLL--EWANDHYDLVIVDTPPMLAVSDAAVVGRSVGTSLLVARFG 674

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1151113182 239 GYTEQELDDFLQQTPET--NLVGTVLNKVADEKE-YAPYGY 276
Cdd:PRK09841  675 LNTAKEVSLSMQRLEQAgvNIKGAILNGVIKRAStAYSYGY 715
FlhG COG0455
MinD-like ATPase FlhG/YlxH, activator of the FlhF-type GTPase [Cell cycle control, cell ...
 109-270 1.86e-10

MinD-like ATPase FlhG/YlxH, activator of the FlhF-type GTPase [Cell cycle control, cell division, chromosome partitioning, Cell motility];


Pssm-ID: 440223 [Multi-domain]  Cd Length: 230  Bit Score: 59.52  E-value: 1.86e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 109 VAINLAMSIAQLPtRRALLVDLDLRCPSVLRYLGVGADNSLNDFLEDKCSFEETLLKPQlPRLSVTGASRRIENSTEQLA 188
Cdd:COG0455     2 VAVNLAAALARLG-KRVLLVDADLGLANLDVLLGLEPKATLADVLAGEADLEDAIVQGP-GGLDVLPGGSGPAELAELDP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 189 SRKIQDVVSSTRSNIgdGVVIFDLPPVLfSDDAISILPKIDCALLVLPDggyteqELD---------DFLQQTPETNLVG 259
Cdd:COG0455    80 EERLIRVLEELERFY--DVVLVDTGAGI-SDSVLLFLAAADEVVVVTTP------EPTsitdayallKLLRRRLGVRRAG 150

                         170
                  ....*....|.
gi 1151113182 260 TVLNKVADEKE 270
Cdd:COG0455   151 VVVNRVRSEAE 161
CpaE-like cd03111
pilus assembly ATPase CpaE; This protein family consists of proteins similar to the cpaE ...
 93-265 2.99e-09

pilus assembly ATPase CpaE; This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains 7 genes: pilA, cpaA, cpaB, cpaC, cpaD, cpaE and cpaF. These genes are clustered together on chromosome.


Pssm-ID: 349765 [Multi-domain]  Cd Length: 235  Bit Score: 56.13  E-value: 2.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  93 RTLAIVSPAPGAGKSVVAINLAMSIAQLPTRRALLVDLDLRCPSVLRYLGVGADNSLNDFLEDKCSFEETLLKPQL---- 168
Cdd:cd03111     1 RVVAVVGAKGGVGASTLAVNLAQELAQRAKDKVLLIDLDLPFGDLGLYLNLRPDYDLADVIQNLDRLDRTLLDSAVtrhs 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 169 PRLSVTGASRRIENStEQLASRKIQDVVSSTRSNIgdGVVIFDLPPVLfSDDAISILPKIDCALLVlpdggyTEQEL--- 245
Cdd:cd03111    81 SGLSLLPAPQELEDL-EALGAEQVDKLLQVLRAFY--DHIIVDLGHFL-DEVTLAVLEAADEILLV------TQQDLpsl 150

                         170       180
                  ....*....|....*....|....*..
gi 1151113182 246 -------DDFLQQTPETNLVGTVLNKV 265
Cdd:cd03111   151 rnarrllDSLRELEGSSDRLRLVLNRY 177
ParA COG1192
ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein ...
 93-216 6.33e-09

ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ [Cell cycle control, cell division, chromosome partitioning, Cell motility];


Pssm-ID: 440805 [Multi-domain]  Cd Length: 253  Bit Score: 55.25  E-value: 6.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  93 RTLAIVSPAPGAGKSVVAINLAMSIAQLPtRRALLVDLDlrcP--SVLRYLGVG---ADNSLNDFLEDKCSFEETLLKPQ 167
Cdd:COG1192     2 KVIAVANQKGGVGKTTTAVNLAAALARRG-KRVLLIDLD---PqgNLTSGLGLDpddLDPTLYDLLLDDAPLEDAIVPTE 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1151113182 168 LPRLSVTGASRRIENSTEQLASR-----KIQDVVSSTRSNigDGVVIFDLPPVL 216
Cdd:COG1192    78 IPGLDLIPANIDLAGAEIELVSRpgrelRLKRALAPLADD--YDYILIDCPPSL 129
PRK11519 PRK11519
tyrosine-protein kinase Wzc;
95-276 9.63e-08

tyrosine-protein kinase Wzc;


Pssm-ID: 183173 [Multi-domain]  Cd Length: 719  Bit Score: 52.85  E-value: 9.63e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  95 LAIVSPAPGAGKSVVAINLAMSIAQlPTRRALLVDLDLRCPSVLRYLGVGADNSLNDFLEDKCSFEETLLKPQLPRLSVT 174
Cdd:PRK11519  529 LMMTGVSPSIGKTFVCANLAAVISQ-TNKRVLLIDCDMRKGYTHELLGTNNVNGLSDILIGQGDITTAAKPTSIANFDLI 607

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182 175 GASRRIENSTEQLASRKIQDVVSSTRSNIgdGVVIFDLPPVLFSDDAISILPKIDCALLVLPDGGYTEQELDDFLQQTPE 254
Cdd:PRK11519  608 PRGQVPPNPSELLMSERFAELVNWASKNY--DLVLIDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFEQ 685

                         170       180
                  ....*....|....*....|....*
gi 1151113182 255 --TNLVGTVLNKVADE-KEYAPYGY 276
Cdd:PRK11519  686 ngIPVKGVILNSIFRRaSAYQDYGY 710
FlhG-like cd02038
MinD-like ATPase FlhG; FlhG is a member of the SIMIBI superfamily. FlhG (also known as YlxH) ...
 93-234 1.06e-07

MinD-like ATPase FlhG; FlhG is a member of the SIMIBI superfamily. FlhG (also known as YlxH) is a major determinant for a variety of flagellation patterns. It effects location and number of bacterial flagella during C-ring assembly.


Pssm-ID: 349758 [Multi-domain]  Cd Length: 230  Bit Score: 51.42  E-value: 1.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  93 RTLAIVSPAPGAGKSVVAINLAMSIAQLpTRRALLVDLDLRCPSVLRYLGVGADNSLNDFLEDKCSFEEtLLKPQLPRLS 172
Cdd:cd02038     1 RIIAVTSGKGGVGKTNVSANLALALSKL-GKRVLLLDADLGLANLDILLGLAPKKTLGDVLKGRVSLED-IIVEGPEGLD 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1151113182 173 V----TGASRRIENSTEQLAsrKIQDVVSSTRSNIgDgVVIFDLPPVLfSDDAISILPKIDCALLV 234
Cdd:cd02038    79 IipggSGMEELANLDPEQKA--KLIEELSSLESNY-D-YLLIDTGAGI-SRNVLDFLLAADEVIVV 139
MinD cd02036
septum site-determining protein MinD; Septum site-determining protein MinD is part of the ...
 93-198 8.44e-05

septum site-determining protein MinD; Septum site-determining protein MinD is part of the operon MinCDE that determines the site of the formation of a septum at mid-cell, an important part of bacterial cell division. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal role, selecting the mid-cell over other sites through the activation and regulation of MinC and MinE. MinD is a membrane-associated ATPase, related to nitrogenase iron protein.


Pssm-ID: 349756 [Multi-domain]  Cd Length: 236  Bit Score: 42.96  E-value: 8.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  93 RTLAIVSPAPGAGKSVVAINLAMSIAQLpTRRALLVDLDLRcpsvLRYLGV--GADN----SLNDFLEDKCSFEETLLK- 165
Cdd:cd02036     1 RVIVITSGKGGVGKTTTTANLGVALAKL-GKKVLLIDADIG----LRNLDLilGLENrivyTLVDVLEGECRLEQALIKd 75

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1151113182 166 PQLPRLSVTGASRRIENstEQLASRKIQDVVSS 198
Cdd:cd02036    76 KRWENLYLLPASQTRDK--DALTPEKLEELVKE 106
Mrp_NBP35 cd02037
Mrp/NBP35 ATP-binding protein family; Mrp/NBP35 ATP-binding family protein are typically ...
 93-143 2.86e-04

Mrp/NBP35 ATP-binding protein family; Mrp/NBP35 ATP-binding family protein are typically iron-sulfur (FeS) cluster scaffolds that function to assemble nascent FeS clusters for transfer to FeS-requiring enzymes. Members include the eukaryotic nucleotide-binding protein 1 (NUBP1) which is a component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery and the archael [NiFe] hydrogenase maturation protein HypB which is required for nickel insertion into [NiFe] hydrogenase.


Pssm-ID: 349757 [Multi-domain]  Cd Length: 213  Bit Score: 40.95  E-value: 2.86e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1151113182  93 RTLAIVSPAPGAGKSVVAINLAMSIAQLPTRRALLvDLDLRCPSVLRYLGV 143
Cdd:cd02037     1 HIIAVLSGKGGVGKSTVAVNLALALAKKGYKVGLL-DADIYGPSIPRLLGV 50
ParA pfam10609
NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid ...
 93-143 6.75e-04

NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.


Pssm-ID: 431392 [Multi-domain]  Cd Length: 246  Bit Score: 40.13  E-value: 6.75e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1151113182  93 RTLAIVSPAPGAGKSVVAINLAMSIAQLPTRRALLvDLDLRCPSVLRYLGV 143
Cdd:pfam10609   4 HVIAVASGKGGVGKSTVAVNLALALARLGYKVGLL-DADIYGPSIPRMLGL 53
AAA_31 pfam13614
AAA domain; This family includes a wide variety of AAA domains including some that have lost ...
 93-216 3.66e-03

AAA domain; This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.


Pssm-ID: 433350 [Multi-domain]  Cd Length: 177  Bit Score: 37.56  E-value: 3.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1151113182  93 RTLAIVSPAPGAGKSVVAINLAMSIAQLpTRRALLVDLDlrcP-----SVLRYLGVGADNSLNDFLEDKCSFEETLLKPQ 167
Cdd:pfam13614   2 KVIAIANQKGGVGKTTTSVNLAAALAKK-GKKVLLIDLD---PqgnatSGLGIDKNNVEKTIYELLIGECNIEEAIIKTV 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1151113182 168 LPRLSVTGAS---RRIENSTEQLASRKI--QDVVSSTRSNIgDgVVIFDLPPVL 216
Cdd:pfam13614  78 IENLDLIPSNidlAGAEIELIGIENRENilKEALEPVKDNY-D-YIIIDCPPSL 129
ParAB_family cd02042
partition proteins ParAB family; ParA and ParB of Caulobacter crescentus belong to a conserved ...
 93-131 7.41e-03

partition proteins ParAB family; ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.


Pssm-ID: 349760 [Multi-domain]  Cd Length: 130  Bit Score: 35.98  E-value: 7.41e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1151113182  93 RTLAIVSPAPGAGKSVVAINLAMSIAQLpTRRALLVDLD 131
Cdd:cd02042     1 KVIAVANQKGGVGKTTLAVNLAAALALR-GKRVLLIDLD 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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