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Conserved domains on  [gi|1168744861|ref|WP_080316922|]
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rhomboid protease YqgP, partial [Bacillus subtilis]

Protein Classification

rhomboid family intramembrane serine protease( domain architecture ID 13665003)

rhomboid family intramembrane serine protease is a membrane-bound protein that catalyzes regulated intramembrane proteolysis, resulting in the release of functional polypeptides from their membrane anchors

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GlpG COG0705
Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein ...
 155-337 4.14e-49

Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 440469 [Multi-domain]  Cd Length: 189  Bit Score: 166.57  E-value: 4.14e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 155 GKPIFTYLFIALQILMFFLLEINGGStntetLVAFGAKENSLIAQGEWWRLLTPIVLHIGIAHLAFNTLALWSVGTAVER 234
Cdd:COG0705     1 RLPPVTLALIALNVLVFLLQLLLGGE-----LLNWLALVPARLLLGELWRLLTSMFLHGGFLHLLFNMLALWVFGPLLER 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 235 MYGSGRFLLIYLAAGITGSIASFVFSP---YPSAGASGAIFGCLGALLYVALsNRKMFLRTIGTNIIVIIIINLGFGFA- 310
Cdd:COG0705    76 RLGSKRFLLLYLLSGLGGGLLQLLFSPgsgYPLVGASGAIFGLLGALLVLGP-RRRVLLLFIPIPALLFLLVWLLLGLLf 154

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1168744861 311 ----VSNIDNSGHIGGLIGGFFAAAALGLPK 337
Cdd:COG0705   155 gllgGGGIAWEAHLGGLLAGLLLALLLRKLR 185
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 369-470 2.97e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.06  E-value: 2.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 369 QESALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLY 448
Cdd:COG4783     3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLAL 82

                          90       100
                  ....*....|....*....|..
gi 1168744861 449 AEKNELAQAEKAIRLAVKLKPK 470
Cdd:COG4783    83 LKAGDYDEALALLEKALKLDPE 104
 
Name Accession Description Interval E-value
GlpG COG0705
Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein ...
 155-337 4.14e-49

Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440469 [Multi-domain]  Cd Length: 189  Bit Score: 166.57  E-value: 4.14e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 155 GKPIFTYLFIALQILMFFLLEINGGStntetLVAFGAKENSLIAQGEWWRLLTPIVLHIGIAHLAFNTLALWSVGTAVER 234
Cdd:COG0705     1 RLPPVTLALIALNVLVFLLQLLLGGE-----LLNWLALVPARLLLGELWRLLTSMFLHGGFLHLLFNMLALWVFGPLLER 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 235 MYGSGRFLLIYLAAGITGSIASFVFSP---YPSAGASGAIFGCLGALLYVALsNRKMFLRTIGTNIIVIIIINLGFGFA- 310
Cdd:COG0705    76 RLGSKRFLLLYLLSGLGGGLLQLLFSPgsgYPLVGASGAIFGLLGALLVLGP-RRRVLLLFIPIPALLFLLVWLLLGLLf 154

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1168744861 311 ----VSNIDNSGHIGGLIGGFFAAAALGLPK 337
Cdd:COG0705   155 gllgGGGIAWEAHLGGLLAGLLLALLLRKLR 185
Rhomboid pfam01694
Rhomboid family; This family contains integral membrane proteins that are related to ...
 196-337 6.14e-45

Rhomboid family; This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.


Pssm-ID: 426384  Cd Length: 147  Bit Score: 154.30  E-value: 6.14e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 196 LIAQGEWWRLLTPIVLHIGIAHLAFNTLALWSVGTAVERMYGSGRFLLIYLAAGITGSIASFVFSPY--PSAGASGAIFG 273
Cdd:pfam01694   1 PVQPGQLWRLITSMFLHAGWLHLLFNMLALLFFGGPLERILGSVRFLLLYLLSGIAGSLLSYLFSPLstPSVGASGAIFG 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1168744861 274 CLGALLYVALSNRKMFLRTIGTNIIVIIIINLGFGFAV---SNIDNSGHIGGLIGGFFAAAALGLPK 337
Cdd:pfam01694  81 LLGALLVLGPRNRILLFGLIGALLALLLFILLNLVLGLlpgNGVSNLAHLGGLLVGLLLGFILLRRP 147
PTZ00101 PTZ00101
rhomboid-1 protease; Provisional
 101-327 3.70e-19

rhomboid-1 protease; Provisional


Pssm-ID: 185445  Cd Length: 278  Bit Score: 87.21  E-value: 3.70e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 101 LRDDLQAVFPSFRTEDCTEEHISFEDAQMAReRFLSLVLkqeeqrkteaavfqngkPIFTY----LFIALQILMFFLLEI 176
Cdd:PTZ00101   10 YRDDYGENTPFNRAEKYYQSQSSFIQRSKPI-DVLNLIF-----------------PHFTWksfiMAISIIQIIVFIISV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 177 NGGSTNTET-----LVAFGAKENSLIAQGEWWRLLTPIVLHIGIAHLAFNTLALWSVGTAVERMYGSGRFLLIYLAAGIT 251
Cdd:PTZ00101   72 SIKPADFLTpsdslLVTLGANVASRIKQGEIHRLILPIFLHANIFHTFFNVFFQLRMGFTLEKNYGIVKIIILYFLTGIY 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 252 GSI--ASFVFSPYpSAGASGAIFGCLG------ALLYVALSNRKMFLrtIGTNIIVIIIINLGFGFAVSNIDNSGHIGGL 323
Cdd:PTZ00101  152 GNIlsSSVTYCPI-KVGASTSGMGLLGivtselILLWHVIRHRERVV--FNIIFFSLISFFYYFTFNGSNIDHVGHLGGL 228


                  ....
gi 1168744861 324 IGGF 327
Cdd:PTZ00101  229 LSGI 232
rhom_GG_sort TIGR03902
rhomboid family GlyGly-CTERM serine protease; This model describes a rhomboid-like ...
 195-290 2.19e-12

rhomboid family GlyGly-CTERM serine protease; This model describes a rhomboid-like intramembrane serine protease. Its species distribution closely matches model TIGR03501, GlyGly-CTERM, which describes a protein targeting domain analogous to LPXTG and PEP-CTERM. In a number of species (Ralstonia eutropha ,R. metallidurans, R. solanacearum, Marinobacter aquaeolei, etc) with just one GlyGly-CTERM protein (i.e., a dedicated system), the rhombosortase and GlyGly-CTERM genes are adjacent.


Pssm-ID: 274845  Cd Length: 154  Bit Score: 64.90  E-value: 2.19e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 195 SLIAQGEWWRLLTPIVLHIGIAHLAFNTLALWSVGTAVERMYGSGRFLLIYLAAGITGSIASFVFSP----YpsAGASGA 270
Cdd:TIGR03902   9 AAILDGEWWRLLTGHFVHLNWWHLLMNLAGLLLLWALFGRHLRARRLLLLLLLLSLLISLGLLLFLPslqwY--VGLSGV 86

                          90       100
                  ....*....|....*....|..
gi 1168744861 271 IFG--CLGALLYVALSNRKMFL 290
Cdd:TIGR03902  87 LHGlfAWGALRDIRYGRRSGWL 108
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 369-470 2.97e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.06  E-value: 2.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 369 QESALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLY 448
Cdd:COG4783     3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLAL 82

                          90       100
                  ....*....|....*....|..
gi 1168744861 449 AEKNELAQAEKAIRLAVKLKPK 470
Cdd:COG4783    83 LKAGDYDEALALLEKALKLDPE 104
LcrH_SycD TIGR02552
type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in ...
 376-487 2.49e-08

type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in type III secretion operons. LcrH, from Yersinia is believed to have a regulatory function in the low-calcium response of the secretion system. The same protein is also known as SycD (SYC = Specific Yop Chaperone) for its chaperone role. In Pseudomonas, where the homolog is known as PcrH, the chaperone role has been demonstrated and the regulatory role appears to be absent. ScyD/LcrH contains three central tetratricopeptide-like repeats that are predicted to fold into an all-alpha-helical array.


Pssm-ID: 274197 [Multi-domain]  Cd Length: 135  Bit Score: 52.68  E-value: 2.49e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 376 QASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELA 455
Cdd:TIGR02552  23 LAYNLYQQGRYDEALKLFQLLAAYDPYNSRYWLGLAACCQMLKEYEEAIDAYALAAALDPDDPRPYFHAAECLLALGEPE 102

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1168744861 456 QAEKAIRLAVKLKPKEQRYKELQQQIENNKES 487
Cdd:TIGR02552 103 SALKALDLAIEICGENPEYSELKERAEAMLES 134
TPR_19 pfam14559
Tetratricopeptide repeat;
418-481 1.38e-07

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 48.35  E-value: 1.38e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1168744861 418 GEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKPKEQRYKELQQQI 481
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 371-486 6.00e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.93  E-value: 6.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 371 SALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKD-HASYYYLALLYA 449
Cdd:cd24142     1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYLYLGQLSG 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1168744861 450 EKNELAQAEKAIRLAvklkpkEQRYKELQQQIENNKE 486
Cdd:cd24142    81 GEEALQYYEKGIEIL------EEELQALQAASAEAEE 111
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 371-482 3.20e-03

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 39.77  E-value: 3.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 371 SALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAE 450
Cdd:PLN03088    3 KDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMK 82

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1168744861 451 KNELAQAEKAIRLAVKLKPKEQRYKELQQQIE 482
Cdd:PLN03088   83 LEEYQTAKAALEKGASLAPGDSRFTKLIKECD 114
 
Name Accession Description Interval E-value
GlpG COG0705
Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein ...
 155-337 4.14e-49

Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440469 [Multi-domain]  Cd Length: 189  Bit Score: 166.57  E-value: 4.14e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 155 GKPIFTYLFIALQILMFFLLEINGGStntetLVAFGAKENSLIAQGEWWRLLTPIVLHIGIAHLAFNTLALWSVGTAVER 234
Cdd:COG0705     1 RLPPVTLALIALNVLVFLLQLLLGGE-----LLNWLALVPARLLLGELWRLLTSMFLHGGFLHLLFNMLALWVFGPLLER 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 235 MYGSGRFLLIYLAAGITGSIASFVFSP---YPSAGASGAIFGCLGALLYVALsNRKMFLRTIGTNIIVIIIINLGFGFA- 310
Cdd:COG0705    76 RLGSKRFLLLYLLSGLGGGLLQLLFSPgsgYPLVGASGAIFGLLGALLVLGP-RRRVLLLFIPIPALLFLLVWLLLGLLf 154

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1168744861 311 ----VSNIDNSGHIGGLIGGFFAAAALGLPK 337
Cdd:COG0705   155 gllgGGGIAWEAHLGGLLAGLLLALLLRKLR 185
Rhomboid pfam01694
Rhomboid family; This family contains integral membrane proteins that are related to ...
 196-337 6.14e-45

Rhomboid family; This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.


Pssm-ID: 426384  Cd Length: 147  Bit Score: 154.30  E-value: 6.14e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 196 LIAQGEWWRLLTPIVLHIGIAHLAFNTLALWSVGTAVERMYGSGRFLLIYLAAGITGSIASFVFSPY--PSAGASGAIFG 273
Cdd:pfam01694   1 PVQPGQLWRLITSMFLHAGWLHLLFNMLALLFFGGPLERILGSVRFLLLYLLSGIAGSLLSYLFSPLstPSVGASGAIFG 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1168744861 274 CLGALLYVALSNRKMFLRTIGTNIIVIIIINLGFGFAV---SNIDNSGHIGGLIGGFFAAAALGLPK 337
Cdd:pfam01694  81 LLGALLVLGPRNRILLFGLIGALLALLLFILLNLVLGLlpgNGVSNLAHLGGLLVGLLLGFILLRRP 147
PTZ00101 PTZ00101
rhomboid-1 protease; Provisional
 101-327 3.70e-19

rhomboid-1 protease; Provisional


Pssm-ID: 185445  Cd Length: 278  Bit Score: 87.21  E-value: 3.70e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 101 LRDDLQAVFPSFRTEDCTEEHISFEDAQMAReRFLSLVLkqeeqrkteaavfqngkPIFTY----LFIALQILMFFLLEI 176
Cdd:PTZ00101   10 YRDDYGENTPFNRAEKYYQSQSSFIQRSKPI-DVLNLIF-----------------PHFTWksfiMAISIIQIIVFIISV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 177 NGGSTNTET-----LVAFGAKENSLIAQGEWWRLLTPIVLHIGIAHLAFNTLALWSVGTAVERMYGSGRFLLIYLAAGIT 251
Cdd:PTZ00101   72 SIKPADFLTpsdslLVTLGANVASRIKQGEIHRLILPIFLHANIFHTFFNVFFQLRMGFTLEKNYGIVKIIILYFLTGIY 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 252 GSI--ASFVFSPYpSAGASGAIFGCLG------ALLYVALSNRKMFLrtIGTNIIVIIIINLGFGFAVSNIDNSGHIGGL 323
Cdd:PTZ00101  152 GNIlsSSVTYCPI-KVGASTSGMGLLGivtselILLWHVIRHRERVV--FNIIFFSLISFFYYFTFNGSNIDHVGHLGGL 228


                  ....
gi 1168744861 324 IGGF 327
Cdd:PTZ00101  229 LSGI 232
rhom_GG_sort TIGR03902
rhomboid family GlyGly-CTERM serine protease; This model describes a rhomboid-like ...
 195-290 2.19e-12

rhomboid family GlyGly-CTERM serine protease; This model describes a rhomboid-like intramembrane serine protease. Its species distribution closely matches model TIGR03501, GlyGly-CTERM, which describes a protein targeting domain analogous to LPXTG and PEP-CTERM. In a number of species (Ralstonia eutropha ,R. metallidurans, R. solanacearum, Marinobacter aquaeolei, etc) with just one GlyGly-CTERM protein (i.e., a dedicated system), the rhombosortase and GlyGly-CTERM genes are adjacent.


Pssm-ID: 274845  Cd Length: 154  Bit Score: 64.90  E-value: 2.19e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 195 SLIAQGEWWRLLTPIVLHIGIAHLAFNTLALWSVGTAVERMYGSGRFLLIYLAAGITGSIASFVFSP----YpsAGASGA 270
Cdd:TIGR03902   9 AAILDGEWWRLLTGHFVHLNWWHLLMNLAGLLLLWALFGRHLRARRLLLLLLLLSLLISLGLLLFLPslqwY--VGLSGV 86

                          90       100
                  ....*....|....*....|..
gi 1168744861 271 IFG--CLGALLYVALSNRKMFL 290
Cdd:TIGR03902  87 LHGlfAWGALRDIRYGRRSGWL 108
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 369-470 2.97e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.06  E-value: 2.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 369 QESALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLY 448
Cdd:COG4783     3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLAL 82

                          90       100
                  ....*....|....*....|..
gi 1168744861 449 AEKNELAQAEKAIRLAVKLKPK 470
Cdd:COG4783    83 LKAGDYDEALALLEKALKLDPE 104
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 372-482 3.57e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 60.79  E-value: 3.57e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 372 ALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEK 451
Cdd:COG4235    19 GWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQ 98

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1168744861 452 NELAQAEKAIRLAVKLKPKEQRYKELQQQIE 482
Cdd:COG4235    99 GDYAEAIAAWQKLLALLPADAPARLLEASIA 129
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 363-470 2.74e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.90  E-value: 2.74e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 363 LHSPSHQESALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYY 442
Cdd:COG2956   103 LELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALL 182

                          90       100
                  ....*....|....*....|....*...
gi 1168744861 443 YLALLYAEKNELAQAEKAIRLAVKLKPK 470
Cdd:COG2956   183 LLAELYLEQGDYEEAIAALERALEQDPD 210
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 329-469 6.67e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.55  E-value: 6.67e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 329 AAAALGLPKAGAFGKRLLSAVLLIALAAGFLYYGLHSPSHQESALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLK 408
Cdd:COG3914    37 LAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALF 116

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1168744861 409 ILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKP 469
Cdd:COG3914   117 NLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDP 177
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 372-471 7.66e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 57.12  E-value: 7.66e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 372 ALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEK 451
Cdd:COG4783    40 AFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRAL 119

                          90       100
                  ....*....|....*....|
gi 1168744861 452 NELAQAEKAIRLAVKLKPKE 471
Cdd:COG4783   120 GRPDEAIAALEKALELDPDD 139
PRK10907 PRK10907
intramembrane serine protease GlpG; Provisional
 159-280 1.12e-09

intramembrane serine protease GlpG; Provisional


Pssm-ID: 182828 [Multi-domain]  Cd Length: 276  Bit Score: 59.25  E-value: 1.12e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 159 FTYLFIALQILMFFLLEINGGSTnTETLVAFGAkENSLiaQGEWWRLLTPIVLHIGIAHLAFNTLALWSVGTAVERMYGS 238
Cdd:PRK10907   96 LTLGVMIACVVVFILMQILGDQT-VMLWLAWPF-DPSL--KFELWRYFTHALLHFSLLHILFNLLWWWYLGGAVEKRLGS 171

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1168744861 239 GRFLLIylaagitgSIASFVFSPYPSAGASGAIFGCLGALLY 280
Cdd:PRK10907  172 GKLIVI--------TLISALLSGWVQSKFSGPWFGGLSGVVY 205
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
372-470 3.65e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.32  E-value: 3.65e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 372 ALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEK 451
Cdd:COG0457    10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQAL 89

                          90
                  ....*....|....*....
gi 1168744861 452 NELAQAEKAIRLAVKLKPK 470
Cdd:COG0457    90 GRYEEALEDYDKALELDPD 108
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 372-482 4.26e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.43  E-value: 4.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 372 ALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEK 451
Cdd:COG2956    78 ALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ 157

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1168744861 452 NELAQAEKAIRLAVKLKPKEQRYKELQQQIE 482
Cdd:COG2956   158 GDYDEAIEALEKALKLDPDCARALLLLAELY 188
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 327-469 5.32e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.97  E-value: 5.32e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 327 FFAAAALGLPKAGAFGKRLLSAVLLIALAAGFLYYGLHSPSHQESALIQQASELYQEGKYEEVTELLNEEAAQKDASADL 406
Cdd:COG5010    11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPEL 90

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1168744861 407 LKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKP 469
Cdd:COG5010    91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
372-470 1.81e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 55.40  E-value: 1.81e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 372 ALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEK 451
Cdd:COG0457    44 ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLEL 123

                          90
                  ....*....|....*....
gi 1168744861 452 NELAQAEKAIRLAVKLKPK 470
Cdd:COG0457   124 GRYDEAIEAYERALELDPD 142
LcrH_SycD TIGR02552
type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in ...
 376-487 2.49e-08

type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in type III secretion operons. LcrH, from Yersinia is believed to have a regulatory function in the low-calcium response of the secretion system. The same protein is also known as SycD (SYC = Specific Yop Chaperone) for its chaperone role. In Pseudomonas, where the homolog is known as PcrH, the chaperone role has been demonstrated and the regulatory role appears to be absent. ScyD/LcrH contains three central tetratricopeptide-like repeats that are predicted to fold into an all-alpha-helical array.


Pssm-ID: 274197 [Multi-domain]  Cd Length: 135  Bit Score: 52.68  E-value: 2.49e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 376 QASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELA 455
Cdd:TIGR02552  23 LAYNLYQQGRYDEALKLFQLLAAYDPYNSRYWLGLAACCQMLKEYEEAIDAYALAAALDPDDPRPYFHAAECLLALGEPE 102

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1168744861 456 QAEKAIRLAVKLKPKEQRYKELQQQIENNKES 487
Cdd:TIGR02552 103 SALKALDLAIEICGENPEYSELKERAEAMLES 134
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 364-474 3.17e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.15  E-value: 3.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 364 HSPSHQEsALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYY 443
Cdd:COG3914   107 LNPDNAE-ALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNN 185

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1168744861 444 LALLYAEKNELAQAEKAIRLAVKLKPKEQRY 474
Cdd:COG3914   186 LGNALQDLGRLEEAIAAYRRALELDPDNADA 216
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 350-481 3.36e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.74  E-value: 3.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 350 LLIALAAGFLYYglhspshqesaliQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLER 429
Cdd:COG2956     1 LLLPVAAALGWY-------------FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQK 67

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1168744861 430 AVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKPKEQRYKELQQQI 481
Cdd:COG2956    68 LLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEI 119
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
380-473 4.49e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.55  E-value: 4.49e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 380 LYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLlERAVKKEPKDHASYYYLALLYAEKNELAQAEK 459
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                          90
                  ....*....|....
gi 1168744861 460 AIRLAVKLKPKEQR 473
Cdd:COG3063    81 YLERALELDPSALR 94
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 328-469 6.09e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.38  E-value: 6.09e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 328 FAAAALGLPKAGAFGKRLLSAVLLIALAAGFLYYGLHSPSHQESALIQQASELYQEGKYEEVTELLNEEAAQKDASADLL 407
Cdd:COG3914     7 LALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAAL 86

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1168744861 408 KILAvsdikIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKP 469
Cdd:COG3914    87 LLQA-----LGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNP 143
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 367-486 1.04e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.19  E-value: 1.04e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 367 SHQESALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLAL 446
Cdd:COG2956    39 PETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAE 118

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1168744861 447 LYAEKNELAQAEKAIRLAVKLKPKE-QRYKELQQQIENNKE 486
Cdd:COG2956   119 IYEQEGDWEKAIEVLERLLKLGPENaHAYCELAELYLEQGD 159
TPR_19 pfam14559
Tetratricopeptide repeat;
418-481 1.38e-07

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 48.35  E-value: 1.38e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1168744861 418 GEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKPKEQRYKELQQQI 481
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 391-473 2.18e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 49.62  E-value: 2.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 391 ELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKPK 470
Cdd:COG4235     4 ARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPD 83


                  ...
gi 1168744861 471 EQR 473
Cdd:COG4235    84 NPE 86
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 401-471 2.90e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.81  E-value: 2.90e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1168744861 401 DASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKPKE 471
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDE 71
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 353-473 3.88e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 49.57  E-value: 3.88e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 353 ALAAGFLYYGLHSPSHQESALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVK 432
Cdd:COG5010     3 ALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQ 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1168744861 433 KEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKPKEQR 473
Cdd:COG5010    83 LDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPN 123
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 372-469 1.36e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 49.73  E-value: 1.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 372 ALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEK 451
Cdd:COG2956   146 AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225

                          90
                  ....*....|....*...
gi 1168744861 452 NELAQAEKAIRLAVKLKP 469
Cdd:COG2956   226 GDPEEALELLRKALELDP 243
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
372-484 1.66e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 49.23  E-value: 1.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 372 ALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEK 451
Cdd:COG0457    78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKL 157

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1168744861 452 NELAQAEKAIRLAVKLKPKEQRYKELQQQIENN 484
Cdd:COG0457   158 GRYEEALELLEKLEAAALAALLAAALGEAALAL 190
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
404-470 4.57e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.08  E-value: 4.57e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1168744861 404 ADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKPK 470
Cdd:COG0457     8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPD 74
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 379-483 5.05e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 45.37  E-value: 5.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 379 ELYQEGKYEEVTELLN---EEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDH---ASYYYLALLYAEKN 452
Cdd:COG1729     2 ALLKAGDYDEAIAAFKaflKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPkapDALLKLGLSYLELG 81

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1168744861 453 ELAQAEKAIRLAVKLKPKEQRYKELQQQIEN 483
Cdd:COG1729    82 DYDKARATLEELIKKYPDSEAAKEARARLAR 112
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 372-466 5.83e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.80  E-value: 5.83e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 372 ALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHAsYYYLALLYAEK 451
Cdd:COG2956   180 ALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL-LLALADLLERK 258

                          90
                  ....*....|....*
gi 1168744861 452 NELAQAEKAIRLAVK 466
Cdd:COG2956   259 EGLEAALALLERQLR 273
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 391-486 2.82e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.62  E-value: 2.82e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 391 ELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKPK 470
Cdd:TIGR02917 588 AILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPD 667

                          90
                  ....*....|....*.
gi 1168744861 471 EQRYKELQQQIENNKE 486
Cdd:TIGR02917 668 NTEAQIGLAQLLLAAK 683
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 422-470 3.10e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.46  E-value: 3.10e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1168744861 422 QAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKPK 470
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPD 49
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 371-486 6.00e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.93  E-value: 6.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 371 SALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKD-HASYYYLALLYA 449
Cdd:cd24142     1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYLYLGQLSG 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1168744861 450 EKNELAQAEKAIRLAvklkpkEQRYKELQQQIENNKE 486
Cdd:cd24142    81 GEEALQYYEKGIEIL------EEELQALQAASAEAEE 111
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
348-470 8.38e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.75  E-value: 8.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 348 AVLLIALAAGFLYYGLHSPSHQE----SALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQA 423
Cdd:COG4785    47 ALAAAALAAAALAAERIDRALALpdlaQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAA 126

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1168744861 424 VSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKPK 470
Cdd:COG4785   127 LEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPN 173
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 410-471 1.06e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 40.40  E-value: 1.06e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1168744861 410 LAVSDIKIGEYDQAVSLLERAVKKE---PKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKPKE 471
Cdd:pfam13432   3 LARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 368-477 1.56e-04

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 43.75  E-value: 1.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 368 HQESALIQQASELYQEGKYEEVTELLnEEAAQKDASADLLKILAvsDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALL 447
Cdd:COG3071   191 RDPELAAAYARALIALGDHDEAERLL-REALKRQWDPRLVRLYG--RLQGGDPAKQLKRAEKWLKKHPNDPDLLLALGRL 267

                          90       100       110
                  ....*....|....*....|....*....|
gi 1168744861 448 YAEKNELAQAEKAIRLAVKLKPKEQRYKEL 477
Cdd:COG3071   268 CLRNQLWGKAREYLEAALALRPSAEAYAEL 297
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
338-470 1.68e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.98  E-value: 1.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 338 AGAFGKRLLSAVLLIALAAGFLYYGLHSPSHqesALIQQASELYQEGKYEEVTELLNEEAAQKDAS--------ADLLKI 409
Cdd:COG4785     2 YALALALLLALALAAAAASKAAILLAALLFA---AVLALAIALADLALALAAAALAAAALAAERIDralalpdlAQLYYE 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1168744861 410 LAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKPK 470
Cdd:COG4785    79 RGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPD 139
TPR_17 pfam13431
Tetratricopeptide repeat;
426-459 8.16e-04

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 36.75  E-value: 8.16e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1168744861 426 LLERAVKKEPKDHASYYYLALLYAEKNELAQAEK 459
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 380-459 8.95e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.99  E-value: 8.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 380 LYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEK 459
Cdd:TIGR02917 813 LYLELKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARK 892
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 366-470 1.13e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 1.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 366 PSHQESALIQQASElYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLA 445
Cdd:TIGR02917 292 PEYLPALLLAGASE-YQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLG 370

                          90       100
                  ....*....|....*....|....*
gi 1168744861 446 LLYAEKNELAQAEKAIRLAVKLKPK 470
Cdd:TIGR02917 371 EAYLALGDFEKAAEYLAKATELDPE 395
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 369-469 1.39e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 1.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 369 QESALIQQASELY-QEGKYEEVTELLNEEAAQK---------------------DASADLLK-------------ILAVS 413
Cdd:TIGR02917 361 DDPAALSLLGEAYlALGDFEKAAEYLAKATELDpenaaartqlgisklsqgdpsEAIADLETaaqldpelgradlLLILS 440

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1168744861 414 DIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKP 469
Cdd:TIGR02917 441 YLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEP 496
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 397-472 1.92e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.84  E-value: 1.92e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1168744861 397 AAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLK-PKEQ 472
Cdd:TIGR02917  15 SACGDQSPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGyPKNQ 91
TPR_19 pfam14559
Tetratricopeptide repeat;
383-447 2.86e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 36.02  E-value: 2.86e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1168744861 383 EGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALL 447
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 371-482 3.20e-03

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 39.77  E-value: 3.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 371 SALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAE 450
Cdd:PLN03088    3 KDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMK 82

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1168744861 451 KNELAQAEKAIRLAVKLKPKEQRYKELQQQIE 482
Cdd:PLN03088   83 LEEYQTAKAALEKGASLAPGDSRFTKLIKECD 114
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 377-470 3.28e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 3.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 377 ASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQ 456
Cdd:TIGR02917 336 ASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSE 415

                          90
                  ....*....|....
gi 1168744861 457 AEKAIRLAVKLKPK 470
Cdd:TIGR02917 416 AIADLETAAQLDPE 429
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 365-469 3.48e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 3.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 365 SPSHQEsALIQQASELYQEGKYEEVTELLNEE-AAQKDASADLLKiLAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYY 443
Cdd:TIGR02917 189 DPGNVD-ALLLKGDLLLSLGNIELALAAYRKAiALRPNNIAVLLA-LATILIEAGEFEEAEKHADALLKKAPNSPLAHYL 266

                          90       100
                  ....*....|....*....|....*.
gi 1168744861 444 LALLYAEKNELAQAEKAIRLAVKLKP 469
Cdd:TIGR02917 267 KALVDFQKKNYEDARETLQDALKSAP 292
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 371-477 3.67e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 3.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 371 SALIQQASELYQEGKYEEVTELLneEAAQKDASADLLKILAVSDIKI--GEYDQAVSLLERAVKKEPKDHASYYYLALLY 448
Cdd:TIGR02917 500 PAAANLARIDIQEGNPDDAIQRF--EKVLTIDPKNLRAILALAGLYLrtGNEEEAVAWLEKAAELNPQEIEPALALAQYY 577

                          90       100
                  ....*....|....*....|....*....
gi 1168744861 449 AEKNELAQAEKAIRLAVKLKPKEQRYKEL 477
Cdd:TIGR02917 578 LGKGQLKKALAILNEAADAAPDSPEAWLM 606
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 372-468 4.47e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 39.59  E-value: 4.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 372 ALIQQASELYQEGKYEEVTELLNEEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEK 451
Cdd:COG3914   148 AYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQA 227

                          90
                  ....*....|....*..
gi 1168744861 452 NELAQAEKAIRLAVKLK 468
Cdd:COG3914   228 CDWEVYDRFEELLAALA 244
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 395-470 6.30e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 6.30e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1168744861 395 EEAAQKDASADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYAEKNELAQAEKAIRLAVKLKPK 470
Cdd:TIGR02917 727 RKALKRAPSSQNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPD 802
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 371-487 8.08e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.91  E-value: 8.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 371 SALIQQASELYQEGKYEEVTELLnEEAAQKDAS-ADLLKILAVSDIKIGEYDQAVSLLERAVKKEPKDHASYYYLALLYA 449
Cdd:TIGR02917 160 YAKLGLAQLALAENRFDEARALI-DEVLTADPGnVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILI 238

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1168744861 450 EKNELAQAEK---AIRLAVKLKPKEQRYKELQQQIENNKES 487
Cdd:TIGR02917 239 EAGEFEEAEKhadALLKKAPNSPLAHYLKALVDFQKKNYED 279
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
374-474 8.54e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 37.94  E-value: 8.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1168744861 374 IQQASELYQEGKYEEVTELLnEEAAQKDA--SADLLKILAVSDIKIGEYDQAVSLLERAVKKEP--KDHASYYYLALLYA 449
Cdd:COG4700    93 VRLADALLELGRYDEAIELY-EEALTGIFadDPHILLGLAQALFELGRYAEALETLEKLIAKNPdfKSSDAHLLYARALE 171

                          90       100
                  ....*....|....*....|....*.
gi 1168744861 450 EKNELAQAEKAIRLAVKLKPK-EQRY 474
Cdd:COG4700   172 ALGDLEAAEAELEALARRYSGpEARY 197
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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