|
Name |
Accession |
Description |
Interval |
E-value |
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
6-530 |
0e+00 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 641.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 6 LQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQQGELTGEETVLE 85
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGLRIGYLPQEPPLDDDLTVLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 86 TLESVFEPQRRMEAELRSLEQEMAESGSDPEalrilggKYDTLTREFERSNGYGWRSSVQGVLAGLEL-REFQDMKTGLL 164
Cdd:COG0488 81 TVLDGDAELRALEAELEELEAKLAEPDEDLE-------RLAELQEEFEALGGWEAEARAEEILSGLGFpEEDLDRPVSEL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 165 SGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGAVLVISHDRYFLDRVCGRMAELLLGNVETYSGN 244
Cdd:COG0488 154 SGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKNYPGTVLVVSHDRYFLDRVATRILELDRGKLTLYPGN 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 245 YTEYLEKRTTVYENRMRAWKLQQKEIARQEAIIamyRRF-NKEKSIRIANSKQKRLDMVERLEKPEDESTIRFRFETRRR 323
Cdd:COG0488 234 YSAYLEQRAERLEQEAAAYAKQQKKIAKEEEFI---RRFrAKARKAKQAQSRIKALEKLEREEPPRRDKTVEIRFPPPER 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 324 TGDDVLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVDLGYYDQHQSEL 403
Cdd:COG0488 311 LGKKVLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLGETVKIGYFDQHQEEL 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 404 HENKTVLDEVWDRFPRMEQYEVRGALGLFLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREA 483
Cdd:COG0488 391 DPDKTVLDELRDGAPGGTEQEVRGYLGRFLFSGDDAFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLDIETLEA 470
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 1226689869 484 LENALSDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKEYLGNYDSY 530
Cdd:COG0488 471 LEEALDDFPGTVLLVSHDRYFLDRVATRILEFEDGGVREYPGGYDDY 517
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
2-530 |
4.84e-111 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 344.61 E-value: 4.84e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 2 IILALQDVKKSF-GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQQGELTGE 80
Cdd:TIGR03719 3 YIYTMNRVSKVVpPKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQPGIKVGYLPQEPQLDPT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 81 ETVLETLESVFEPQRRMEAELRSLEQEMAESGSDPEALRILGGKydtLTREFERSNGYGWRSSVQGVLAGLELREFqDMK 160
Cdd:TIGR03719 83 KTVRENVEEGVAEIKDALDRFNEISAKYAEPDADFDKLAAEQAE---LQEIIDAADAWDLDSQLEIAMDALRCPPW-DAD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 161 TGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGAVLVISHDRYFLDRVCGRMAELLLGNVET 240
Cdd:TIGR03719 159 VTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHLQEYPGTVVAVTHDRYFLDNVAGWILELDRGRGIP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 241 YSGNYTEYLEKRTTVYENRMRAWKLQQKEI------------ARQ---EAIIAMYRRFNKEKSIRIANSKQKRLDMVERL 305
Cdd:TIGR03719 239 WEGNYSSWLEQKQKRLEQEEKEESARQKTLkrelewvrqspkGRQaksKARLARYEELLSQEFQKRNETAEIYIPPGPRL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 306 ekpedestirfrfetrrrtGDDVLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVI 385
Cdd:TIGR03719 319 -------------------GDKVIEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTI 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 386 RWGTGVDLGYYDQHQSELHENKTVLDEVWDRFPRME--QYEV--RGALGLFLFTGDEVFEPVSTLSGGEKGRVALTELML 461
Cdd:TIGR03719 380 EIGETVKLAYVDQSRDALDPNKTVWEEISGGLDIIKlgKREIpsRAYVGRFNFKGSDQQKKVGQLSGGERNRVHLAKTLK 459
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 462 RKDNVLLLDEPTNHLDMDSREALENALSDFPGTIISVSHDRYFINRFAEKVWVLDGN-EIKEYLGNYDSY 530
Cdd:TIGR03719 460 SGGNVLLLDEPTNDLDVETLRALEEALLNFAGCAVVISHDRWFLDRIATHILAFEGDsHVEWFEGNFSEY 529
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
13-530 |
1.02e-110 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 343.03 E-value: 1.02e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 13 FGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQQGELTGEETVLETLesvfe 92
Cdd:PRK15064 11 FGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDPNERLGKLRQDQFAFEEFTVLDTV----- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 93 pqrRM-EAELRSLEQEMAESGSDPEALRILGGKYDTLTREFERSNGYGWRSSVQGVLAGLELREfqDMKTGLLSG---GE 168
Cdd:PRK15064 86 ---IMgHTELWEVKQERDRIYALPEMSEEDGMKVADLEVKFAEMDGYTAEARAGELLLGVGIPE--EQHYGLMSEvapGW 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 169 RTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGAVLVISHDRYFLDRVCGRMAELLLGNVETYSGNYTEY 248
Cdd:PRK15064 161 KLRVLLAQALFSNPDILLLDEPTNNLDINTIRWLEDVLNERNSTMIIISHDRHFLNSVCTHMADLDYGELRVYPGNYDEY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 249 LEKRTTVYENrmrawklQQKEIARQEAIIA----MYRRF--NKEKSiRIANSKQKRLDMVERLE-KPEDESTIRFRFETR 321
Cdd:PRK15064 241 MTAATQARER-------LLADNAKKKAQIAelqsFVSRFsaNASKA-KQATSRAKQIDKIKLEEvKPSSRQNPFIRFEQD 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 322 RRTGDDVLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVDLGYYDQ-HQ 400
Cdd:PRK15064 313 KKLHRNALEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSENANIGYYAQdHA 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 SELHENKTVLDevWdrfprMEQYE--------VRGALGLFLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEP 472
Cdd:PRK15064 393 YDFENDLTLFD--W-----MSQWRqegddeqaVRGTLGRLLFSQDDIKKSVKVLSGGEKGRMLFGKLMMQKPNVLVMDEP 465
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 473 TNHLDMDSREALENALSDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKEYLGNYDSY 530
Cdd:PRK15064 466 TNHMDMESIESLNMALEKYEGTLIFVSHDREFVSSLATRIIEITPDGVVDFSGTYEEY 523
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
2-536 |
4.37e-105 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 329.00 E-value: 4.37e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 2 IILALQDVKKSFGT-HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQQGELTGE 80
Cdd:PRK11819 5 YIYTMNRVSKVVPPkKQILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPAPGIKVGYLPQEPQLDPE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 81 ETVLETLESVFEPQRRMEAELRSLEQEMAESGSDPEALRILGGKydtLTREFERSNGYGWRSSVQGVLAGLELREfQDMK 160
Cdd:PRK11819 85 KTVRENVEEGVAEVKAALDRFNEIYAAYAEPDADFDALAAEQGE---LQEIIDAADAWDLDSQLEIAMDALRCPP-WDAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 161 TGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGAVLVISHDRYFLDRVCGRMAELLLGNVET 240
Cdd:PRK11819 161 VTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLEQFLHDYPGTVVAVTHDRYFLDNVAGWILELDRGRGIP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 241 YSGNYTEYLEKRttvyENRMRawKLQQKEIARQEAI------IAM--YRRFNKEKSiRIAN-------SKQKRLDMVE-- 303
Cdd:PRK11819 241 WEGNYSSWLEQK----AKRLA--QEEKQEAARQKALkrelewVRQspKARQAKSKA-RLARyeellseEYQKRNETNEif 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 304 -----RLekpedestirfrfetrrrtGDDVLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVE 378
Cdd:PRK11819 314 ippgpRL-------------------GDKVIEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQE 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 379 KPDAGVIRWGTGVDLGYYDQHQSELHENKTVLDEVWD--RFPRMEQYEV--RGALGLFLFTGDEVFEPVSTLSGGEKGRV 454
Cdd:PRK11819 375 QPDSGTIKIGETVKLAYVDQSRDALDPNKTVWEEISGglDIIKVGNREIpsRAYVGRFNFKGGDQQKKVGVLSGGERNRL 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 455 ALTeLMLRKD-NVLLLDEPTNHLDMDSREALENALSDFPGTIISVSHDRYFINRFAEKVWVLDGN-EIKEYLGNYDSY-A 531
Cdd:PRK11819 455 HLA-KTLKQGgNVLLLDEPTNDLDVETLRALEEALLEFPGCAVVISHDRWFLDRIATHILAFEGDsQVEWFEGNFQEYeE 533
|
....*
gi 1226689869 532 LKVSR 536
Cdd:PRK11819 534 DKKRR 538
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
12-632 |
1.72e-94 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 303.80 E-value: 1.72e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 12 SFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQQGELTGEETVL----ETL 87
Cdd:PRK11147 12 SFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIVARLQQDPPRNVEGTVYdfvaEGI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 88 ESVFEPQRRMEAELRSLEQEMAEsgsdpealRILGgKYDTLTREFERSNGYGWRSSVQGVLAGLELREfqDMKTGLLSGG 167
Cdd:PRK11147 92 EEQAEYLKRYHDISHLVETDPSE--------KNLN-ELAKLQEQLDHHNLWQLENRINEVLAQLGLDP--DAALSSLSGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 168 ERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGAVLVISHDRYFLDRVCGRMAELLLGNVETYSGNYTE 247
Cdd:PRK11147 161 WLRKAALGRALVSNPDVLLLDEPTNHLDIETIEWLEGFLKTFQGSIIFISHDRSFIRNMATRIVDLDRGKLVSYPGNYDQ 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 248 YLEK-----RTTVYENRMRAWKLQQKEIARQEAIIAmyRRFNKEKSIRIAnsKQKRldmVERLEKPEDESTIRFRFETRR 322
Cdd:PRK11147 241 YLLEkeealRVEELQNAEFDRKLAQEEVWIRQGIKA--RRTRNEGRVRAL--KALR---RERSERREVMGTAKMQVEEAS 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 323 RTGDDVLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVDLGYYDQHQSE 402
Cdd:PRK11147 314 RSGKIVFEMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCGTKLEVAYFDQHRAE 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 403 LHENKTVLDEVWDrfprmEQYEV------RGALGL---FLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPT 473
Cdd:PRK11147 394 LDPEKTVMDNLAE-----GKQEVmvngrpRHVLGYlqdFLFHPKRAMTPVKALSGGERNRLLLARLFLKPSNLLILDEPT 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 474 NHLDMDSREALENALSDFPGTIISVSHDRYFINRFAEKVWVLDGN-EIKEYLGNY--------DSYALKVSRDQEPDGSA 544
Cdd:PRK11147 469 NDLDVETLELLEELLDSYQGTVLLVSHDRQFVDNTVTECWIFEGNgKIGRYVGGYhdarqqqaQYLALKQPAVKKKEEAA 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 545 PQQTRTAmdkekrRSREEERKLREQKEaLKAAEQAIARAEKEAGEMEAELADPEIWKDPDKaaETTRRYNALKD---EIE 621
Cdd:PRK11147 549 APKAETV------KRSSKKLSYKLQRE-LEQLPQLLEDLEAEIEALQAQVADADFFSQPHE--QTQKVLADLADaeqELE 619
|
650
....*....|.
gi 1226689869 622 RLYEQYDALES 632
Cdd:PRK11147 620 VAFERWEELEA 630
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
1-611 |
1.33e-84 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 277.82 E-value: 1.33e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKsfGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQqgeltgE 80
Cdd:PRK10636 1 MIVFSSLQIRR--GVRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGNWQLAWVNQ------E 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 81 ETVLET--LESVFEPQRrmeaELRSLEQEM--AESGSDPEALRILGGKYDTLtrefersNGYGWRSSVQGVLAGLELREF 156
Cdd:PRK10636 73 TPALPQpaLEYVIDGDR----EYRQLEAQLhdANERNDGHAIATIHGKLDAI-------DAWTIRSRAASLLHGLGFSNE 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 157 Q-DMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGAVLVISHDRYFLDRVCGRMAELLL 235
Cdd:PRK10636 142 QlERPVSDFSGGWRMRLNLAQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDPIVDKIIHIEQ 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 236 GNVETYSGNYTEYLEKRTTVYENRMRAWKLQQKEIARQEAIIamyRRFNKEKSIriANSKQKRLDMVERLE---KPEDES 312
Cdd:PRK10636 222 QSLFEYTGNYSSFEVQRATRLAQQQAMYESQQERVAHLQSYI---DRFRAKATK--AKQAQSRIKMLERMEliaPAHVDN 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 313 TIRFRFETRRRTGDDVLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVD 392
Cdd:PRK10636 297 PFHFSFRAPESLPNPLLKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIK 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 393 LGYYDQHQSE-LHENKTVLDEVWDRFPRMEQYEVRGALGLFLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDE 471
Cdd:PRK10636 377 LGYFAQHQLEfLRADESPLQHLARLAPQELEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPNLLLLDE 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 472 PTNHLDMDSREALENALSDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKEYLGNYDSYA-----LKVSRDQEPDGSAPQ 546
Cdd:PRK10636 457 PTNHLDLDMRQALTEALIDFEGALVVVSHDRHLLRSTTDDLYLVHDGKVEPFDGDLEDYQqwlsdVQKQENQTDEAPKEN 536
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 547 QTRTAMDKEKRRSREEERKLREQ--KEALKAAEQAIARAEKEAGEMEAELADPEIWkDPDKAAETTR 611
Cdd:PRK10636 537 NANSAQARKDQKRREAELRTQTQplRKEIARLEKEMEKLNAQLAQAEEKLGDSELY-DQSRKAELTA 602
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
12-530 |
9.70e-64 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 223.58 E-value: 9.70e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 12 SFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAgLETADSgtvsMQKGLRIGYLAQqgELTGEE-TVLE-TLES 89
Cdd:PLN03073 186 SVGGRDLIVDASVTLAFGRHYGLVGRNGTGKTTFLRYMA-MHAIDG----IPKNCQILHVEQ--EVVGDDtTALQcVLNT 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 90 VFEPQRRMEAELRSLEQE-------------MAESGSDPEALriLGGKYDTLTREFERSNGYGWRSSVQGVLAGLELR-E 155
Cdd:PLN03073 259 DIERTQLLEEEAQLVAQQrelefetetgkgkGANKDGVDKDA--VSQRLEEIYKRLELIDAYTAEARAASILAGLSFTpE 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 156 FQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGAVLVISHDRYFLDRVCGRMAELLL 235
Cdd:PLN03073 337 MQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYLLKWPKTFIVVSHAREFLNTVVTDILHLHG 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 236 GNVETYSGNYTEYLEKRTTVYENRMRAWKLQQKEIARQEAIIAMYRRFNKEKSirIANSKQKRLDMVERLEK-------- 307
Cdd:PLN03073 417 QKLVTYKGDYDTFERTREEQLKNQQKAFESNERSRSHMQAFIDKFRYNAKRAS--LVQSRIKALDRLGHVDAvvndpdyk 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 308 -----PEDEStirfrfetrrrtGDDVLMTEGLSKGY-GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPD 381
Cdd:PLN03073 495 fefptPDDRP------------GPPIISFSDASFGYpGGPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPS 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 382 AGVIRWGTGVDLGYYDQHQSE-LHENKTVLDEVWDRFPRMEQYEVRGALGLFLFTGDEVFEPVSTLSGGEKGRVALTELM 460
Cdd:PLN03073 563 SGTVFRSAKVRMAVFSQHHVDgLDLSSNPLLYMMRCFPGVPEQKLRAHLGSFGVTGNLALQPMYTLSGGQKSRVAFAKIT 642
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 461 LRKDNVLLLDEPTNHLDMDSREALENALSDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKEYLGNYDSY 530
Cdd:PLN03073 643 FKKPHILLLDEPSNHLDLDAVEALIQGLVLFQGGVLMVSHDEHLISGSVDELWVVSEGKVTPFHGTFHDY 712
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
332-519 |
1.67e-60 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 198.06 E-value: 1.67e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVDLGYYDQhqselhenktvld 411
Cdd:cd03221 4 ENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTVKIGYFEQ------------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 412 evwdrfprmeqyevrgalglflftgdevfepvstLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDF 491
Cdd:cd03221 71 ----------------------------------LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESIEALEEALKEY 116
|
170 180
....*....|....*....|....*...
gi 1226689869 492 PGTIISVSHDRYFINRFAEKVWVLDGNE 519
Cdd:cd03221 117 PGTVILVSHDRYFLDQVATKIIELEDGK 144
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
2-251 |
1.03e-56 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 199.91 E-value: 1.03e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 2 IILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQ-QGELTGE 80
Cdd:COG0488 314 KVLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLGETVKIGYFDQhQEELDPD 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 81 ETVLETLESVFEPQRrmEAELRSLEQEMAESGSDpealrilggkydtltrefersngygwrssvqgvlaglelrefQDMK 160
Cdd:COG0488 394 KTVLDELRDGAPGGT--EQEVRGYLGRFLFSGDD------------------------------------------AFKP 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 161 TGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGAVLVISHDRYFLDRVCGRMAELLLGNVET 240
Cdd:COG0488 430 VGVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLDIETLEALEEALDDFPGTVLLVSHDRYFLDRVATRILEFEDGGVRE 509
|
250
....*....|.
gi 1226689869 241 YSGNYTEYLEK 251
Cdd:COG0488 510 YPGGYDDYLEK 520
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
4-227 |
9.90e-41 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 144.90 E-value: 9.90e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQqgeltgeetv 83
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTVKIGYFEQ---------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 84 letlesvfepqrrmeaelrsleqemaesgsdpealrilggkydtltrefersngygwrssvqgvlaglelrefqdmktgl 163
Cdd:cd03221 --------------------------------------------------------------------------------
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 164 LSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGAVLVISHDRYFLDRVC 227
Cdd:cd03221 71 LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESIEALEEALKEYPGTVILVSHDRYFLDQVA 134
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
328-501 |
2.80e-33 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 126.44 E-value: 2.80e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW-GTGVDL---GYYDQ----- 398
Cdd:COG4133 2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWnGEPIRDareDYRRRlaylg 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 399 HQSELHENKTVLDEV--WDRF--PRMEQYEVRGALGLFLFTGdevFE--PVSTLSGGEKGRVALTELMLRKDNVLLLDEP 472
Cdd:COG4133 82 HADGLKPELTVRENLrfWAALygLRADREAIDEALEAVGLAG---LAdlPVRQLSAGQKRRVALARLLLSPAPLWLLDEP 158
|
170 180 190
....*....|....*....|....*....|..
gi 1226689869 473 TNHLDMDSREALENALSDFP---GTIISVSHD 501
Cdd:COG4133 159 FTALDAAGVALLAELIAAHLargGAVLLTTHQ 190
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
332-520 |
3.93e-33 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 126.08 E-value: 3.93e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDL------------GYYDQh 399
Cdd:COG4619 4 EGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLD-GKPLsampppewrrqvAYVPQ- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 400 QSELHENkTV---LDEVW----DRFPRMEQYEVRGALGLflftGDEVFE-PVSTLSGGEKGRVALTELMLRKDNVLLLDE 471
Cdd:COG4619 82 EPALWGG-TVrdnLPFPFqlreRKFDRERALELLERLGL----PPDILDkPVERLSGGERQRLALIRALLLQPDVLLLDE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 472 PTNHLDMDSREALENALSDFP----GTIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:COG4619 157 PTSALDPENTRRVEELLREYLaeegRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
332-516 |
1.48e-32 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 122.74 E-value: 1.48e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHqselhenktvld 411
Cdd:cd00267 3 ENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILID-GKDIAKLPLE------------ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 412 evwdrfprmeqyEVRGALGLflftgdevfepVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDF 491
Cdd:cd00267 70 ------------ELRRRIGY-----------VPQLSGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRERLLELLREL 126
|
170 180
....*....|....*....|....*...
gi 1226689869 492 PG---TIISVSHDRYFINRFAEKVWVLD 516
Cdd:cd00267 127 AEegrTVIIVTHDPELAELAADRVIVLK 154
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
2-252 |
2.57e-32 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 131.60 E-value: 2.57e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 2 IILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQQGE-LTGE 80
Cdd:TIGR03719 321 KVIEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIGETVKLAYVDQSRDaLDPN 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 81 ETVLEtlesvfepqrrmeaelrsleqEMAEsGSDpealRILGGKYDTLTRefersnGYGWRSSVQGVlaglelreFQDMK 160
Cdd:TIGR03719 401 KTVWE---------------------EISG-GLD----IIKLGKREIPSR------AYVGRFNFKGS--------DQQKK 440
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 161 TGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGAVLVISHDRYFLDRVCGR-MAELLLGNVE 239
Cdd:TIGR03719 441 VGQLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDVETLRALEEALLNFAGCAVVISHDRWFLDRIATHiLAFEGDSHVE 520
|
250
....*....|...
gi 1226689869 240 TYSGNYTEYLEKR 252
Cdd:TIGR03719 521 WFEGNFSEYEEDK 533
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
332-516 |
2.07e-31 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 121.42 E-value: 2.07e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGD--RILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHqsELHE---- 405
Cdd:cd03225 3 KNLSFSYPDgaRPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVD-GKDLTKLSLK--ELRRkvgl 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 ----------NKTVLDEV--------WDRfPRMEQyEVRGALGLFLFTGDEvFEPVSTLSGGEKGRVALTELMLRKDNVL 467
Cdd:cd03225 80 vfqnpddqffGPTVEEEVafglenlgLPE-EEIEE-RVEEALELVGLEGLR-DRSPFTLSGGQKQRVAIAGVLAMDPDIL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 468 LLDEPTNHLDMDSREALENALSDFPG---TIISVSHDRYFINRFAEKVWVLD 516
Cdd:cd03225 157 LLDEPTAGLDPAGRRELLELLKKLKAegkTIIIVTHDLDLLLELADRVIVLE 208
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
328-520 |
3.71e-30 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 119.38 E-value: 3.71e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDL------------GY 395
Cdd:COG1120 1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLD-GRDLaslsrrelarriAY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 396 YDQHqSELHENKTVLDEV----------WDRFPRMEQYEVRGALGLflfTGDEVFE--PVSTLSGGEKGRVALTELMLRK 463
Cdd:COG1120 80 VPQE-PPAPFGLTVRELValgryphlglFGRPSAEDREAVEEALER---TGLEHLAdrPVDELSGGERQRVLIARALAQE 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 464 DNVLLLDEPTNHLDMDSR-EALE--NALSDFPG-TIISVSHDryfIN---RFAEKVWVLDGNEI 520
Cdd:COG1120 156 PPLLLLDEPTSHLDLAHQlEVLEllRRLARERGrTVVMVLHD---LNlaaRYADRLVLLKDGRI 216
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
3-522 |
1.82e-29 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 122.70 E-value: 1.82e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSF--GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLetadsgtvsmqkglrigyLAQQGELTGE 80
Cdd:COG1123 4 LLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGL------------------LPHGGRISGE 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 81 ETVLETlesvfePQRRMEAELRSLEQEM----AESGSDP--------EALRILGgkydtLTREfersngyGWRSSVQGVL 148
Cdd:COG1123 66 VLLDGR------DLLELSEALRGRRIGMvfqdPMTQLNPvtvgdqiaEALENLG-----LSRA-------EARARVLELL 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 149 AGLELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDL---KSIAWLEEYLAAFHG-AVLVISHDRYFLD 224
Cdd:COG1123 128 EAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEPTTALDVttqAEILDLLRELQRERGtTVLLITHDLGVVA 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 225 RVCGRMAELLLGNVEtysgnyteylekrttvyenrmrawklqqkEIARQEAIIAmyrrfnkeksiriansKQKRLDMVER 304
Cdd:COG1123 208 EIADRVVVMDDGRIV-----------------------------EDGPPEEILA----------------APQALAAVPR 242
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 305 LEKPEDESTirfrfeTRRRTGDDVLMTEGLSKGY-----GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEK 379
Cdd:COG1123 243 LGAARGRAA------PAAAAAEPLLEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLR 316
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 380 PDAGVIRWGtGVDL---------------GYYDQH-QSELHENKTVLDEVWD------RFPRMEQYE-VRGAL---GLfl 433
Cdd:COG1123 317 PTSGSILFD-GKDLtklsrrslrelrrrvQMVFQDpYSSLNPRMTVGDIIAEplrlhgLLSRAERRErVAELLervGL-- 393
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 434 ftGDEVFE-PVSTLSGGEKGRVAL-TELMLRKDnVLLLDEPTNHLDMDSREALENALSD----FPGTIISVSHDRYFINR 507
Cdd:COG1123 394 --PPDLADrYPHELSGGQRQRVAIaRALALEPK-LLILDEPTSALDVSVQAQILNLLRDlqreLGLTYLFISHDLAVVRY 470
|
570
....*....|....*
gi 1226689869 508 FAEKVWVLDGNEIKE 522
Cdd:COG1123 471 IADRVAVMYDGRIVE 485
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
332-520 |
1.09e-28 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 112.53 E-value: 1.09e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHqsELHENKTVLD 411
Cdd:cd03214 3 ENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLD-GKDLASLSPK--ELARKIAYVP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 412 EVWDRFprmeqyevrGALGLflftgdeVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSR-EALE--NAL 488
Cdd:cd03214 80 QALELL---------GLAHL-------ADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQiELLEllRRL 143
|
170 180 190
....*....|....*....|....*....|....*.
gi 1226689869 489 SDFPG-TIISVSHDryfIN---RFAEKVWVLDGNEI 520
Cdd:cd03214 144 ARERGkTVVMVLHD---LNlaaRYADRVILLKDGRI 176
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
332-519 |
3.23e-28 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 110.94 E-value: 3.23e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRI--LFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHqselhenktv 409
Cdd:cd03228 4 KNVSFSYPGRPkpVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILID-GVDLRDLDLE---------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 410 ldevwdrfprmeqyEVRGALGL-----FLFTGDeVFEPVstLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREAL 484
Cdd:cd03228 73 --------------SLRKNIAYvpqdpFLFSGT-IRENI--LSGGQRQRIAIARALLRDPPILILDEATSALDPETEALI 135
|
170 180 190
....*....|....*....|....*....|....*..
gi 1226689869 485 ENALSDFPG--TIISVSHdRYFINRFAEKVWVLDGNE 519
Cdd:cd03228 136 LEALRALAKgkTVIVIAH-RLSTIRDADRIIVLDDGR 171
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
332-528 |
4.73e-28 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 112.43 E-value: 4.73e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGY-GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGyyDQHQSELHE----- 405
Cdd:COG1122 4 ENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVD-GKDIT--KKNLRELRRkvglv 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 ---------NKTVLDEVwdRF-PR---MEQYE----VRGALGLFlftGDEVFE--PVSTLSGGEKGRVAL-TELMLRKDn 465
Cdd:COG1122 81 fqnpddqlfAPTVEEDV--AFgPEnlgLPREEirerVEEALELV---GLEHLAdrPPHELSGGQKQRVAIaGVLAMEPE- 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 466 VLLLDEPTNHLDMDSREALENALSDFPG---TIISVSHDRYFINRFAEKVWVLDGNEI------KEYLGNYD 528
Cdd:COG1122 155 VLVLDEPTAGLDPRGRRELLELLKRLNKegkTVIIVTHDLDLVAELADRVIVLDDGRIvadgtpREVFSDYE 226
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
332-517 |
8.14e-27 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 109.41 E-value: 8.14e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW-GTGV-----DLGYYDQhQSELHE 405
Cdd:COG1121 10 ENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLfGKPPrrarrRIGYVPQ-RAEVDW 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 NK--TVLDEV---------WDRFPRMEQYE-VRGALglflftgDEV----FE--PVSTLSGGEKGRVALTELMLRKDNVL 467
Cdd:COG1121 89 DFpiTVRDVVlmgrygrrgLFRRPSRADREaVDEAL-------ERVgledLAdrPIGELSGGQQQRVLLARALAQDPDLL 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 468 LLDEPTNHLDMDSREALENALSDFPG---TIISVSHDRYFINRFAEKVWVLDG 517
Cdd:COG1121 162 LLDEPFAGVDAATEEALYELLRELRRegkTILVVTHDLGAVREYFDRVLLLNR 214
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
4-226 |
1.51e-26 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 107.56 E-value: 1.51e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGL----------RIGYLAQ 73
Cdd:COG4133 3 LEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPirdaredyrrRLAYLGH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 74 QGELTGEETVLETLEsvFepqrrmeaelrsleqemaesgsdpeALRILGGKYDtltrefersngygwRSSVQGVLAGLEL 153
Cdd:COG4133 83 ADGLKPELTVRENLR--F-------------------------WAALYGLRAD--------------REAIDEALEAVGL 121
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 154 REFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFH---GAVLVISHDRYFLDRV 226
Cdd:COG4133 122 AGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALDAAGVALLAELIAAHLargGAVLLTTHQPLELAAA 197
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
1-230 |
4.61e-26 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 107.25 E-value: 4.61e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILalQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ--------KGLR--IGY 70
Cdd:COG4555 1 MIEV--ENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDgedvrkepREARrqIGV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 71 LAQQGELTGEETVLETLesvfepqrRMEAELRSLEQEMAESgsdpealrilggKYDTLTREFersngygwrssvqgvlag 150
Cdd:COG4555 79 LPDERGLYDRLTVRENI--------RYFAELYGLFDEELKK------------RIEELIELL------------------ 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 151 lELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG---AVLVISHDRYFLDRVC 227
Cdd:COG4555 121 -GLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNGLDVMARRLLREILRALKKegkTVLFSSHIMQEVEALC 199
|
...
gi 1226689869 228 GRM 230
Cdd:COG4555 200 DRV 202
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
337-501 |
5.04e-26 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 105.39 E-value: 5.04e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 337 GYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVDLGYYDQHqSELHEN--KTVLDEV- 413
Cdd:NF040873 1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVAYVPQR-SEVPDSlpLTVRDLVa 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 414 ---------WDRFPRMEQYEVRGAL---GLFLFTGdevfEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSR 481
Cdd:NF040873 80 mgrwarrglWRRLTRDDRAAVDDALervGLADLAG----RQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESR 155
|
170 180
....*....|....*....|...
gi 1226689869 482 EALENALSDFPG---TIISVSHD 501
Cdd:NF040873 156 ERIIALLAEEHArgaTVVVVTHD 178
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
331-520 |
5.22e-26 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 104.79 E-value: 5.22e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 331 TEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGyydQHQSELHENKTVL 410
Cdd:cd03230 3 VRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVL-GKDIK---KEPEEVKRRIGYL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 411 DEVWDRFPRMeqyevrgalglflfTGDEVFEpvstLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSD 490
Cdd:cd03230 79 PEEPSLYENL--------------TVRENLK----LSGGMKQRLALAQALLHDPELLILDEPTSGLDPESRREFWELLRE 140
|
170 180 190
....*....|....*....|....*....|...
gi 1226689869 491 F---PGTIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:cd03230 141 LkkeGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
4-231 |
7.69e-26 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 106.30 E-value: 7.69e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-----SMQKGL-----RIGYLAQ 73
Cdd:COG1131 1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVrvlgeDVARDPaevrrRIGYVPQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 74 QGELTGEETVLETLesvfepqrRMEAELRSLEQEMAEsgsdpealrilggkydtltrefERsngygwrssVQGVLAGLEL 153
Cdd:COG1131 81 EPALYPDLTVRENL--------RFFARLYGLPRKEAR----------------------ER---------IDELLELFGL 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 154 REFQDMKTGLLSGGERTRLCLGR----------MlltepdllllDEPTNHLDLKSIAWLEEYLAAFHG---AVLVISHDR 220
Cdd:COG1131 122 TDAADRKVGTLSGGMKQRLGLALallhdpelliL----------DEPTSGLDPEARRELWELLRELAAegkTVLLSTHYL 191
|
250
....*....|.
gi 1226689869 221 YFLDRVCGRMA 231
Cdd:COG1131 192 EEAERLCDRVA 202
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-226 |
1.45e-25 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 105.94 E-value: 1.45e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM------QKGLRIGYLAQQ 74
Cdd:COG1121 4 MPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLfgkpprRARRRIGYVPQR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 75 GELTGEE--TVLETLESVFEPQRRMEAELRSLEQEMAEsgsdpEALRILGgkydtltrefersngygwrssvqgvlagle 152
Cdd:COG1121 84 AEVDWDFpiTVRDVVLMGRYGRRGLFRRPSRADREAVD-----EALERVG------------------------------ 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 153 LREFQDMKTGLLSGGERTRLCLGR----------MlltepdllllDEPTNHLDLKSIAWLEEYLAAFHG---AVLVISHD 219
Cdd:COG1121 129 LEDLADRPIGELSGGQQQRVLLARalaqdpdlllL----------DEPFAGVDAATEEALYELLRELRRegkTILVVTHD 198
|
250
....*....|..
gi 1226689869 220 -----RYFlDRV 226
Cdd:COG1121 199 lgavrEYF-DRV 209
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
344-474 |
2.67e-25 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 101.96 E-value: 2.67e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 344 FRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWG-----------TGVDLGYYDQHqSELHENKTVLDE 412
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDgqdltdderksLRKEIGYVFQD-PQLFPRLTVREN 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 413 VW---------DRFPRMEQYEVRGALGLFLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTN 474
Cdd:pfam00005 80 LRlglllkglsKREKDARAEEALEKLGLGDLADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
332-516 |
2.80e-25 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 103.04 E-value: 2.80e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQSELHENKTVLD 411
Cdd:cd03229 4 KNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILID-GEDLTDLEDELPPLRRRIGMVF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 412 EVWDRFPRMEQYEVRgALGlflftgdevfepvstLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSD- 490
Cdd:cd03229 83 QDFALFPHLTVLENI-ALG---------------LSGGQQQRVALARALAMDPDVLLLDEPTSALDPITRREVRALLKSl 146
|
170 180
....*....|....*....|....*....
gi 1226689869 491 ---FPGTIISVSHDRYFINRFAEKVWVLD 516
Cdd:cd03229 147 qaqLGITVVLVTHDLDEAARLADRVVVLR 175
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
4-233 |
3.17e-25 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 103.74 E-value: 3.17e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGL-----------RIGYLA 72
Cdd:COG4619 1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPlsampppewrrQVAYVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 73 QQGELtGEETVLETLESVFEPQRR---MEAELRSLEQemaesgsdpealriLGGKYDTLTREFERsngygwrssvqgvla 149
Cdd:COG4619 81 QEPAL-WGGTVRDNLPFPFQLRERkfdRERALELLER--------------LGLPPDILDKPVER--------------- 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 150 glelrefqdmktglLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKS----IAWLEEYLAAFHGAVLVISHDRYFLDR 225
Cdd:COG4619 131 --------------LSGGERQRLALIRALLLQPDVLLLDEPTSALDPENtrrvEELLREYLAEEGRAVLWVSHDPEQIER 196
|
....*...
gi 1226689869 226 VCGRMAEL 233
Cdd:COG4619 197 VADRVLTL 204
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
328-538 |
3.97e-25 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 104.55 E-value: 3.97e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQH-------- 399
Cdd:COG4555 1 MIEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILID-GEDVRKEPREarrqigvl 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 400 --QSELHENKTVLD---------EVWDRFPRMEQYEVRGALGLFLFTgDevfEPVSTLSGGEKGRVALTELMLRKDNVLL 468
Cdd:COG4555 80 pdERGLYDRLTVREniryfaelyGLFDEELKKRIEELIELLGLEEFL-D---RRVGELSTGMKKKVALARALVHDPKVLL 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 469 LDEPTNHLDMDSREALEN---ALSDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKeYLGNYDSYALKVSRDQ 538
Cdd:COG4555 156 LDEPTNGLDVMARRLLREilrALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVV-AQGSLDELREEIGEEN 227
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
4-233 |
7.97e-25 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 101.32 E-value: 7.97e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVS----------MQKGLRIGYLAQ 73
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKvlgkdikkepEEVKRRIGYLPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 74 QGELTGEETVLETLEsvfepqrrmeaelrsleqemaesgsdpealrilggkydtltrefersngygwrssvqgvlaglel 153
Cdd:cd03230 81 EPSLYENLTVRENLK----------------------------------------------------------------- 95
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 154 refqdmktglLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEY---LAAFHGAVLVISHDRYFLDRVCGRM 230
Cdd:cd03230 96 ----------LSGGMKQRLALAQALLHDPELLILDEPTSGLDPESRREFWELlreLKKEGKTILLSSHILEEAERLCDRV 165
|
...
gi 1226689869 231 AEL 233
Cdd:cd03230 166 AIL 168
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
4-218 |
1.06e-24 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 102.30 E-value: 1.06e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-----SMQKGL----RIGYLAQQ 74
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEItfdgkSYQKNIealrRIGALIEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 75 GELTGEETVLETLESvfepqrrmeaelrsleqemaesgsdpeALRILGGKYdtltrefersngygwrSSVQGVLAGLELR 154
Cdd:cd03268 81 PGFYPNLTARENLRL---------------------------LARLLGIRK----------------KRIDEVLDVVGLK 117
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 155 EFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEY---LAAFHGAVLVISH 218
Cdd:cd03268 118 DSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLDPDGIKELRELilsLRDQGITVLISSH 184
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
332-520 |
1.65e-23 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 98.75 E-value: 1.65e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWG----TGV-----DLGYYDQHQSe 402
Cdd:cd03259 4 KGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDgrdvTGVpperrNIGMVFQDYA- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 403 LHENKTVLDEVwdRFP----RMEQYEVRGALGLFLF-TGDEVFE--PVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNH 475
Cdd:cd03259 83 LFPHLTVAENI--AFGlklrGVPKAEIRARVRELLElVGLEGLLnrYPHELSGGQQQRVALARALAREPSLLLLDEPLSA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1226689869 476 LDMDSREALENALSD----FPGTIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:cd03259 161 LDAKLREELREELKElqreLGITTIYVTHDQEEALALADRIAVMNEGRI 209
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
332-517 |
1.96e-23 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 98.76 E-value: 1.96e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIR------WGTGVDLGYYDQHQSELHE 405
Cdd:cd03235 3 EDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRvfgkplEKERKRIGYVPQRRSIDRD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 -NKTVLDEV---------WDRFPRMEQYE-VRGALGlflFTGDEVFE--PVSTLSGGEKGRVALTELMLRKDNVLLLDEP 472
Cdd:cd03235 83 fPISVRDVVlmglyghkgLFRRLSKADKAkVDEALE---RVGLSELAdrQIGELSGGQQQRVLLARALVQDPDLLLLDEP 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1226689869 473 TNHLDMDSREA---LENALSDFPGTIISVSHDRYFINRFAEKVWVLDG 517
Cdd:cd03235 160 FAGVDPKTQEDiyeLLRELRREGMTILVVTHDLGLVLEYFDRVLLLNR 207
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
6-226 |
4.49e-23 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 97.60 E-value: 4.49e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 6 LQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM------QKGLRIGYLAQQGE--- 76
Cdd:cd03235 2 VEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVfgkpleKERKRIGYVPQRRSidr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 77 ---LTGEETVLETLESVFEPQRRMEAElrsleqemaesgsdpealrilggkydtltrefersngygWRSSVQGVLAGLEL 153
Cdd:cd03235 82 dfpISVRDVVLMGLYGHKGLFRRLSKA---------------------------------------DKAKVDEALERVGL 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 154 REFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG---AVLVISHD----RYFLDRV 226
Cdd:cd03235 123 SELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRRegmTILVVTHDlglvLEYFDRV 202
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
3-226 |
4.83e-23 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 98.58 E-value: 4.83e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-----------SMQKGLRIGYL 71
Cdd:COG1120 1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVlldgrdlaslsRRELARRIAYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 72 AQQGELTGEETVLETLESVFEPQRRMEAELRSLEQEMAEsgsdpEALRILGgkydtltrefersngygwrssvqgvLAGL 151
Cdd:COG1120 81 PQEPPAPFGLTVRELVALGRYPHLGLFGRPSAEDREAVE-----EALERTG-------------------------LEHL 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 152 ELREFQDmktglLSGGERTRLCLGR----------MlltepdllllDEPTNHLDLKS-IAWLE--EYLAAFHG-AVLVIS 217
Cdd:COG1120 131 ADRPVDE-----LSGGERQRVLIARalaqepplllL----------DEPTSHLDLAHqLEVLEllRRLARERGrTVVMVL 195
|
250
....*....|....
gi 1226689869 218 HD-----RYFlDRV 226
Cdd:COG1120 196 HDlnlaaRYA-DRL 208
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
4-252 |
5.74e-23 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 103.05 E-value: 5.74e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQQGELTGEETv 83
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSENANIGYYAQDHAYDFEND- 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 84 letlESVFE--PQRRMEaelrsleqemaesGSDPEALR-ILG----GKYDTltrefersngygwRSSVQgvlaglelref 156
Cdd:PRK15064 399 ----LTLFDwmSQWRQE-------------GDDEQAVRgTLGrllfSQDDI-------------KKSVK----------- 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 157 qdmktgLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGAVLVISHDRYFLDRVCGRMAELLLG 236
Cdd:PRK15064 438 ------VLSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMDMESIESLNMALEKYEGTLIFVSHDREFVSSLATRIIEITPD 511
|
250
....*....|....*.
gi 1226689869 237 NVETYSGNYTEYLEKR 252
Cdd:PRK15064 512 GVVDFSGTYEEYLRSQ 527
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
297-522 |
6.20e-23 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 103.76 E-value: 6.20e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 297 KRLDMVerLEKPEDESTIRFRFETRRRTGDDVLmtEGLSKGYGDR--ILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCL 374
Cdd:COG2274 446 ERLDDI--LDLPPEREEGRSKLSLPRLKGDIEL--ENVSFRYPGDspPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLL 521
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 375 IGVEKPDAGVIRWGtGVDL------------GYYDQHqSELHeNKTVLDEV--WDRFPRMEqyEVRGAL---GLFLFTGD 437
Cdd:COG2274 522 LGLYEPTSGRILID-GIDLrqidpaslrrqiGVVLQD-VFLF-SGTIRENItlGDPDATDE--EIIEAArlaGLHDFIEA 596
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 438 -------EVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPG--TIISVSHDRYFInRF 508
Cdd:COG2274 597 lpmgydtVVGEGGSNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLKgrTVIIIAHRLSTI-RL 675
|
250
....*....|....
gi 1226689869 509 AEKVWVLDGNEIKE 522
Cdd:COG2274 676 ADRIIVLDKGRIVE 689
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
4-520 |
8.21e-23 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 102.57 E-value: 8.21e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLET--ADSGTVSMQKGL--RIGYLAQQ----- 74
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQyePTSGRIIYHVALceKCGYVERPskvge 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 75 ------GELTGEETVLETL-ESVFEPQRRMEAELrsLEQEMAESGSDpealRILggkyDTLTREFERSnGYGWRSSVQGV 147
Cdd:TIGR03269 81 pcpvcgGTLEPEEVDFWNLsDKLRRRIRKRIAIM--LQRTFALYGDD----TVL----DNVLEALEEI-GYEGKEAVGRA 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 148 LAGLELREFQDMKTGL---LSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSI----AWLEEYLAAFHGAVLVISHdr 220
Cdd:TIGR03269 150 VDLIEMVQLSHRITHIardLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAklvhNALEEAVKASGISMVLTSH-- 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 221 yfldrvcgrmaelllgnvetysgnYTEYLEKRTTvyenrmRAWKLQQKEIarqeaiiamyrrfnkeksIRIANSKQKRLD 300
Cdd:TIGR03269 228 ------------------------WPEVIEDLSD------KAIWLENGEI------------------KEEGTPDEVVAV 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 301 MVERLEKPEDESTIRFrfetrrrtGDDVLMTEGLSKGYG--DRILFR---DLKMHVRAGDRIALIGDNGTGKSTLLQCLI 375
Cdd:TIGR03269 260 FMEGVSEVEKECEVEV--------GEPIIKVRNVSKRYIsvDRGVVKavdNVSLEVKEGEIFGIVGTSGAGKTTLSKIIA 331
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 376 GVEKPDAGVI------RWGTGVDLGYYDQ----------HQS-ELHENKTVLD--------EVWDRFPRMEQYEVRGALG 430
Cdd:TIGR03269 332 GVLEPTSGEVnvrvgdEWVDMTKPGPDGRgrakryigilHQEyDLYPHRTVLDnlteaiglELPDELARMKAVITLKMVG 411
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 431 LFLFTGDEVFEPV-STLSGGEKGRVALTELMLRKDNVLLLDEPTNHLD----MDSREALENALSDFPGTIISVSHDRYFI 505
Cdd:TIGR03269 412 FDEEKAEEILDKYpDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDpitkVDVTHSILKAREEMEQTFIIVSHDMDFV 491
|
570
....*....|....*
gi 1226689869 506 NRFAEKVWVLDGNEI 520
Cdd:TIGR03269 492 LDVCDRAALMRDGKI 506
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
332-522 |
1.29e-22 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 102.14 E-value: 1.29e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGD-RILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQ---------- 400
Cdd:COG4988 340 EDVSFSYPGgRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILIN-GVDLSDLDPASwrrqiawvpq 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 ----------------------SELHE--NKTVLDEVWDRFPRMEQYEV--RGAlglflftgdevfepvsTLSGGEKGRV 454
Cdd:COG4988 419 npylfagtirenlrlgrpdasdEELEAalEAAGLDEFVAALPDGLDTPLgeGGR----------------GLSGGQAQRL 482
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 455 ALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPG--TIISVSHDRYFInRFAEKVWVLDGNEIKE 522
Cdd:COG4988 483 ALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKgrTVILITHRLALL-AQADRILVLDDGRIVE 551
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
332-522 |
4.30e-22 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 100.61 E-value: 4.30e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGY--GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQhqSELHENKTV 409
Cdd:COG4987 337 EDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLG-GVDLRDLDE--DDLRRRIAV 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 410 LDE---VWD-------RF--PRMEQYEVRGAL---GL--FLFTGDE-----VFEPVSTLSGGEKGRVALTELMLRKDNVL 467
Cdd:COG4987 414 VPQrphLFDttlrenlRLarPDATDEELWAALervGLgdWLAALPDgldtwLGEGGRRLSGGERRRLALARALLRDAPIL 493
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 468 LLDEPTNHLDMDSREALENALSD-FPG-TIISVSHDRYFINRFaEKVWVLDGNEIKE 522
Cdd:COG4987 494 LLDEPTEGLDAATEQALLADLLEaLAGrTVLLITHRLAGLERM-DRILVLEDGRIVE 549
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
4-233 |
9.05e-22 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 94.87 E-value: 9.05e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGT----HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ---------KGLR--I 68
Cdd:COG1124 2 LEVRNLSVSYGQggrrVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDgrpvtrrrrKAFRrrV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 69 GYLAQQGeltgeetvletlESVFEPQRRMEAELRsleqemaesgsdpEALRILGgkydtLTREFERsngygwrssVQGVL 148
Cdd:COG1124 82 QMVFQDP------------YASLHPRHTVDRILA-------------EPLRIHG-----LPDREER---------IAELL 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 149 AGLEL-REFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDL----KSIAWLEEYLAAFHGAVLVISHDRYFL 223
Cdd:COG1124 123 EQVGLpPSFLDRYPHQLSGGQRQRVAIARALILEPELLLLDEPTSALDVsvqaEILNLLKDLREERGLTYLFVSHDLAVV 202
|
250
....*....|
gi 1226689869 224 DRVCGRMAEL 233
Cdd:COG1124 203 AHLCDRVAVM 212
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
332-515 |
3.44e-21 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 97.36 E-value: 3.44e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDR-ILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDL------GYYDQ----HQ 400
Cdd:TIGR02857 325 SGVSVAYPGRrPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVN-GVPLadadadSWRDQiawvPQ 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 SELHENKTVLDEVwdRFPRMEQ--YEVRGAL---GLFLFTGD-------EVFEPVSTLSGGEKGRVALTELMLRKDNVLL 468
Cdd:TIGR02857 404 HPFLFAGTIAENI--RLARPDAsdAEIREALeraGLDEFVAAlpqgldtPIGEGGAGLSGGQAQRLALARAFLRDAPLLL 481
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1226689869 469 LDEPTNHLDMDSREALENALSDFPG--TIISVSHDRYFINRfAEKVWVL 515
Cdd:TIGR02857 482 LDEPTAHLDAETEAEVLEALRALAQgrTVLLVTHRLALAAL-ADRIVVL 529
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
331-501 |
1.52e-20 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 90.89 E-value: 1.52e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 331 TEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVD-----------LGYYDQh 399
Cdd:COG1131 3 VRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVL-GEDvardpaevrrrIGYVPQ- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 400 QSELHENKTVLD--EVWDRFPRMEQYEVRG-------ALGLflftGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLD 470
Cdd:COG1131 81 EPALYPDLTVREnlRFFARLYGLPRKEAREridelleLFGL----TDAADRKVGTLSGGMKQRLGLALALLHDPELLILD 156
|
170 180 190
....*....|....*....|....*....|....
gi 1226689869 471 EPTNHLDMDSREALENALSDFPG---TIISVSHD 501
Cdd:COG1131 157 EPTSGLDPEARRELWELLRELAAegkTVLLSTHY 190
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
332-524 |
1.56e-20 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 91.40 E-value: 1.56e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYG----DRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYD---------- 397
Cdd:COG1124 5 RNLSVSYGqggrRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFD-GRPVTRRRrkafrrrvqm 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 398 --QH-QSELHENKTV------------LDEVWDRFPRM-EQYEVRGALgLFLFtgdevfepVSTLSGGEKGRVAL-TELM 460
Cdd:COG1124 84 vfQDpYASLHPRHTVdrilaeplrihgLPDREERIAELlEQVGLPPSF-LDRY--------PHQLSGGQRQRVAIaRALI 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 461 LRKDnVLLLDEPTNHLDMDSREALENALSD----FPGTIISVSHDRYFINRFAEKVWVLDGNEIKEYL 524
Cdd:COG1124 155 LEPE-LLLLDEPTSALDVSVQAEILNLLKDlreeRGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEEL 221
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
2-311 |
1.76e-20 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 95.79 E-value: 1.76e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 2 IILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQ-QGELTGE 80
Cdd:PRK11147 318 IVFEMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCGTKLEVAYFDQhRAELDPE 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 81 ETVLETLesvfepqrrmeAELRsleQEMAESGSDPEALrilggkydtltrefersnGYgwrssVQGVLaglelreFQDMK 160
Cdd:PRK11147 398 KTVMDNL-----------AEGK---QEVMVNGRPRHVL------------------GY-----LQDFL-------FHPKR 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 161 T----GLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGAVLVISHDRYFLDRVcgrMAELLL- 235
Cdd:PRK11147 434 AmtpvKALSGGERNRLLLARLFLKPSNLLILDEPTNDLDVETLELLEELLDSYQGTVLLVSHDRQFVDNT---VTECWIf 510
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 236 ---GNVETYSGNYTEYLEKRTTVYENRMRAWKlQQKEIARQEAIIAmyrrfnKEKSIRIANSKQKRLD-MVERLEKPEDE 311
Cdd:PRK11147 511 egnGKIGRYVGGYHDARQQQAQYLALKQPAVK-KKEEAAAPKAETV------KRSSKKLSYKLQRELEqLPQLLEDLEAE 583
|
|
| F420-0_ABC_ATP |
TIGR03873 |
proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ... |
329-520 |
2.64e-20 |
|
proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ATP-binding protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and a permease (TIGR03869). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with a F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this ATP-binding protein is a component of an F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.
Pssm-ID: 163585 [Multi-domain] Cd Length: 256 Bit Score: 91.03 E-value: 2.64e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDL------------GYY 396
Cdd:TIGR03873 2 LRLSRVSWSAGGRLIVDGVDVTAPPGSLTGLLGPNGSGKSTLLRLLAGALRPDAGTVDLA-GVDLhglsrrararrvALV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 397 DQHqSELHENKTVLDEV----------WDRFPRMEQYEVRGALGLflfTGDEVF--EPVSTLSGGEKGRVALTELMLRKD 464
Cdd:TIGR03873 81 EQD-SDTAVPLTVRDVValgriphrslWAGDSPHDAAVVDRALAR---TELSHLadRDMSTLSGGERQRVHVARALAQEP 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 465 NVLLLDEPTNHLDMDSREALENALSDFPG---TIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:TIGR03873 157 KLLLLDEPTNHLDVRAQLETLALVRELAAtgvTVVAALHDLNLAASYCDHVVVLDGGRV 215
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
19-192 |
4.23e-20 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 87.32 E-value: 4.23e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQK-----------GLRIGYLAQQGELTGEETVLETL 87
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGqdltdderkslRKEIGYVFQDPQLFPRLTVRENL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 88 EsvfepqrrmeaelrsleqemaesgsdpEALRILGGKYDTLTREFERsngygwrssvqgVLAGLELREF----QDMKTGL 163
Cdd:pfam00005 81 R---------------------------LGLLLKGLSKREKDARAEE------------ALEKLGLGDLadrpVGERPGT 121
|
170 180
....*....|....*....|....*....
gi 1226689869 164 LSGGERTRLCLGRMLLTEPDLLLLDEPTN 192
Cdd:pfam00005 122 LSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
332-501 |
5.40e-20 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 89.07 E-value: 5.40e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDR----ILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIR------WGTGVDLGYYDQHQS 401
Cdd:cd03293 4 RNVSKTYGGGggavTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLvdgepvTGPGPDRGYVFQQDA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 402 eLHENKTVLDEV-----WDRFPRMEQYEVrgALGLFLFTGDEVFE---PvSTLSGGEKGRVALTELMLRKDNVLLLDEPT 473
Cdd:cd03293 84 -LLPWLTVLDNValgleLQGVPKAEARER--AEELLELVGLSGFEnayP-HQLSGGMRQRVALARALAVDPDVLLLDEPF 159
|
170 180 190
....*....|....*....|....*....|..
gi 1226689869 474 NHLDMDSREALENALSD----FPGTIISVSHD 501
Cdd:cd03293 160 SALDALTREQLQEELLDiwreTGKTVLLVTHD 191
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
332-520 |
1.04e-19 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 88.50 E-value: 1.04e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQSELHENK---- 407
Cdd:COG1127 9 RNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVD-GQDITGLSEKELYELRRRigml 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 408 ----------TVLDEVwdRFP------------------RMEQYEVRGALGLFlftgdevfePvSTLSGGEKGRVALTE- 458
Cdd:COG1127 88 fqggalfdslTVFENV--AFPlrehtdlseaeirelvleKLELVGLPGAADKM---------P-SELSGGMRKRVALARa 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 459 LMLRKDnVLLLDEPTNHLDMDSREALEN---ALSD-FPGTIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:COG1127 156 LALDPE-ILLYDEPTAGLDPITSAVIDElirELRDeLGLTSVVVTHDLDSAFAIADRVAVLADGKI 220
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
332-518 |
1.34e-19 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 86.50 E-value: 1.34e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGD--RILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDqhqselhenktv 409
Cdd:cd03246 4 ENVSFRYPGaePPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLD-GADISQWD------------ 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 410 LDEVWDRFPRMEQyEVRgalglfLFTGdEVFEPVstLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALS 489
Cdd:cd03246 71 PNELGDHVGYLPQ-DDE------LFSG-SIAENI--LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQAIA 140
|
170 180 190
....*....|....*....|....*....|...
gi 1226689869 490 DFP---GTIISVSHDRYFINRfAEKVWVL-DGN 518
Cdd:cd03246 141 ALKaagATRIVIAHRPETLAS-ADRILVLeDGR 172
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
354-517 |
1.70e-19 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 87.35 E-value: 1.70e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 354 GDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWG--------TGVDLGYYDQHQSELHENKTVldevwdrFPRMEQYE- 424
Cdd:cd03297 23 EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNgtvlfdsrKKINLPPQQRKIGLVFQQYAL-------FPHLNVREn 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 425 ----------------VRGALGLFLFTGdEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENAL 488
Cdd:cd03297 96 lafglkrkrnredrisVDELLDLLGLDH-LLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPEL 174
|
170 180 190
....*....|....*....|....*....|....
gi 1226689869 489 ----SDFPGTIISVSHDRYFINRFAEKVWVL-DG 517
Cdd:cd03297 175 kqikKNLNIPVIFVTHDLSEAEYLADRIVVMeDG 208
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
4-220 |
1.78e-19 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 87.19 E-value: 1.78e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQK----GL-----RIGYLAQQ 74
Cdd:cd03259 1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGrdvtGVpperrNIGMVFQD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 75 GELTGEETVLETLESVFEPQRRMEAELRSLEQEMaesgsdpealrilggkydtltrefersngygwrssvqgvLAGLELR 154
Cdd:cd03259 81 YALFPHLTVAENIAFGLKLRGVPKAEIRARVREL---------------------------------------LELVGLE 121
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 155 EFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGA----VLVISHDR 220
Cdd:cd03259 122 GLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSALDAKLREELREELKELQRElgitTIYVTHDQ 191
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
332-522 |
1.85e-19 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 87.42 E-value: 1.85e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGY-GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDL---------------GY 395
Cdd:COG2884 5 ENVSKRYpGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVN-GQDLsrlkrreipylrrriGV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 396 YDQ-HQseLHENKTVLDEVwdRFPrME---------QYEVRGAL---GLflftGDEVFEPVSTLSGGEKGRVALTELMLR 462
Cdd:COG2884 84 VFQdFR--LLPDRTVYENV--ALP-LRvtgksrkeiRRRVREVLdlvGL----SDKAKALPHELSGGEQQRVAIARALVN 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 463 KDNVLLLDEPTNHLDMD-SREALE-----NALsdfpG-TIISVSHDRYFINRFAEKVWVLDGNEIKE 522
Cdd:COG2884 155 RPELLLADEPTGNLDPEtSWEIMElleeiNRR----GtTVLIATHDLELVDRMPKRVLELEDGRLVR 217
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
332-520 |
2.00e-19 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 87.20 E-value: 2.00e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIR------WGTGVDLGYYDQH-----Q 400
Cdd:cd03262 4 KNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIidglklTDDKKNINELRQKvgmvfQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 S-ELHENKTVLD-------EVWDRfPRMEQYEvrgalglflfTGDEVFEPV----------STLSGGEKGRVALTE-LML 461
Cdd:cd03262 84 QfNLFPHLTVLEnitlapiKVKGM-SKAEAEE----------RALELLEKVgladkadaypAQLSGGQQQRVAIARaLAM 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 462 RKDnVLLLDEPTNHLDMD-SREALE--NALSDFPGTIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:cd03262 153 NPK-VMLFDEPTSALDPElVGEVLDvmKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
329-522 |
2.70e-19 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 87.49 E-value: 2.70e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQ-------- 400
Cdd:cd03219 1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFD-GEDITGLPPHEiarlgigr 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 ----SELHENKTVLDEV-------------WDRFPRMEQYEVRGALGLFLFTG--DEVFEPVSTLSGGEKGRVALTELML 461
Cdd:cd03219 80 tfqiPRLFPELTVLENVmvaaqartgsgllLARARREEREARERAEELLERVGlaDLADRPAGELSYGQQRRLEIARALA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 462 RKDNVLLLDEPTNHLDMDSREALEN---ALSDFPGTIISVSHDRYFINRFAEKVWVLD-GNEIKE 522
Cdd:cd03219 160 TDPKLLLLDEPAAGLNPEETEELAElirELRERGITVLLVEHDMDVVMSLADRVTVLDqGRVIAE 224
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
329-501 |
2.96e-19 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 87.81 E-value: 2.96e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTG--------VDLGYYDqhq 400
Cdd:PRK11247 13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAplaearedTRLMFQD--- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 SELHENKTVLDEV-------WdrfpRMEQYEVRGALGLflftGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPT 473
Cdd:PRK11247 90 ARLLPWKKVIDNVglglkgqW----RDAALQALAAVGL----ADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPL 161
|
170 180 190
....*....|....*....|....*....|..
gi 1226689869 474 NHLDMDSR----EALENALSDFPGTIISVSHD 501
Cdd:PRK11247 162 GALDALTRiemqDLIESLWQQHGFTVLLVTHD 193
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
6-239 |
3.15e-19 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 87.17 E-value: 3.15e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 6 LQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM---------QKGL-----RIGYL 71
Cdd:cd03261 3 LRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIdgedisglsEAELyrlrrRMGML 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 72 AQQGELTGEETVletLESVFEPQRRMEAELRSLEQEMAEsgsdpEALRILGgkydtltrefersngygwrssvqgvlagl 151
Cdd:cd03261 83 FQSGALFDSLTV---FENVAFPLREHTRLSEEEIREIVL-----EKLEAVG----------------------------- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 152 eLREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYL----AAFHGAVLVISHDRYFLDRVC 227
Cdd:cd03261 126 -LRGAEDLYPAELSGGMKKRVALARALALDPELLLYDEPTAGLDPIASGVIDDLIrslkKELGLTSIMVTHDLDTAFAIA 204
|
250
....*....|..
gi 1226689869 228 GRMAELLLGNVE 239
Cdd:cd03261 205 DRIAVLYDGKIV 216
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
329-490 |
3.17e-19 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 86.26 E-value: 3.17e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLG----------YYDQ 398
Cdd:TIGR01189 1 LAARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWN-GTPLAeqrdepheniLYLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 399 HQSELHENKTVLDEV--WDRFPRMEQYEVRGALGLFLFTGDEVFePVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHL 476
Cdd:TIGR01189 80 HLPGLKPELSALENLhfWAAIHGGAQRTIEDALAAVGLTGFEDL-PAAQLSAGQQRRLALARLWLSRRPLWILDEPTTAL 158
|
170
....*....|....
gi 1226689869 477 DMDSREALENALSD 490
Cdd:TIGR01189 159 DKAGVALLAGLLRA 172
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
3-524 |
3.29e-19 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 91.27 E-value: 3.29e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM--------------QKGLri 68
Cdd:PRK15439 11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIggnpcarltpakahQLGI-- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 69 gYLA-QQGELTGEETVLETLesVFEPQRRMEAElRSLEQEMAESGSDpealrilggkydtltrefersngygwrssvqgv 147
Cdd:PRK15439 89 -YLVpQEPLLFPNLSVKENI--LFGLPKRQASM-QKMKQLLAALGCQ--------------------------------- 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 148 lagLELrefqDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD----LKSIAWLEEYLAAFHGAVLvISHDRYFL 223
Cdd:PRK15439 132 ---LDL----DSSAGSLEVADRQIVEILRGLMRDSRILILDEPTASLTpaetERLFSRIRELLAQGVGIVF-ISHKLPEI 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 224 DRVCGRMAELLLGNVeTYSGNYTEYlekrttvyenrmrawklqqkeiaRQEAIIAMYRRFNKEKSiriANSKQKRLdmve 303
Cdd:PRK15439 204 RQLADRISVMRDGTI-ALSGKTADL-----------------------STDDIIQAITPAAREKS---LSASQKLW---- 252
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 304 rLEKPEDESTirfrfetrRRTGDDVLMTEGLSkGYGdrilFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAG 383
Cdd:PRK15439 253 -LELPGNRRQ--------QAAGAPVLTVEDLT-GEG----FRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGG 318
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 384 VIrWGTGVDLGYY---------------DQHQSEL---------------HENKTVLDEVWDRfPRMEQYevRGALGLFL 433
Cdd:PRK15439 319 RI-MLNGKEINALstaqrlarglvylpeDRQSSGLyldaplawnvcalthNRRGFWIKPAREN-AVLERY--RRALNIKF 394
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 434 FTGDevfEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPG---TIISVSHDRYFINRFAE 510
Cdd:PRK15439 395 NHAE---QAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAAqnvAVLFISSDLEEIEQMAD 471
|
570
....*....|....
gi 1226689869 511 KVWVLDGNEIKEYL 524
Cdd:PRK15439 472 RVLVMHQGEISGAL 485
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
6-233 |
4.95e-19 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 85.98 E-value: 4.95e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 6 LQDVKKSFGTHE--VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-----------SMQKGLRIGYLA 72
Cdd:cd03225 2 LKNLSFSYPDGArpALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVlvdgkdltklsLKELRRKVGLVF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 73 QQGE--LTGEeTVLEtlESVFepqrrmeaelrsleqemaesgsdpeALRILGGKYDTLTREfersngygwrssVQGVLAG 150
Cdd:cd03225 82 QNPDdqFFGP-TVEE--EVAF-------------------------GLENLGLPEEEIEER------------VEEALEL 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 151 LELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGA---VLVISHDRYFLDRVC 227
Cdd:cd03225 122 VGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLKAEgktIIIVTHDLDLLLELA 201
|
....*.
gi 1226689869 228 GRMAEL 233
Cdd:cd03225 202 DRVIVL 207
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
345-520 |
5.22e-19 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 86.10 E-value: 5.22e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 345 RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDL------------GYYDQHQS----ELHENKT 408
Cdd:cd03245 21 DNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLD-GTDIrqldpadlrrniGYVPQDVTlfygTLRDNIT 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 409 VLDEVWDRFPRMEQYEVrgaLGLFLFTGD-------EVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSR 481
Cdd:cd03245 100 LGAPLADDERILRAAEL---AGVTDFVNKhpngldlQIGERGRGLSGGQRQAVALARALLNDPPILLLDEPTSAMDMNSE 176
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1226689869 482 EALENALSDFPG--TIISVSHdRYFINRFAEKVWVLDGNEI 520
Cdd:cd03245 177 ERLKERLRQLLGdkTLIIITH-RPSLLDLVDRIIVMDSGRI 216
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
329-523 |
6.74e-19 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 86.24 E-value: 6.74e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILfRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLgyydqhqSEL---HE 405
Cdd:cd03299 1 LKVENLSKDWKEFKL-KNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILL-NGKDI-------TNLppeKR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 NKTVLDEVWDRFPRMEQYEvRGALGLFLFTGD--EVFEPV-----------------STLSGGEKGRVALTELMLRKDNV 466
Cdd:cd03299 72 DISYVPQNYALFPHMTVYK-NIAYGLKKRKVDkkEIERKVleiaemlgidhllnrkpETLSGGEQQRVAIARALVVNPKI 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 467 LLLDEPTNHLDMDSREALENALSD----FPGTIISVSHDRYFINRFAEKVWVLDGNEIKEY 523
Cdd:cd03299 151 LLLDEPFSALDVRTKEKLREELKKirkeFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQV 211
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
334-517 |
7.45e-19 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 86.31 E-value: 7.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 334 LSKGYGDrilfrdLKMHVRAGD-----RIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYDQHQSELHENkT 408
Cdd:cd03237 6 MKKTLGE------FTLEVEGGSiseseVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEI-ELDTVSYKPQYIKADYEG-T 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 409 V---LDEVWDRFPRMEQY--EVRGALGLflftgDEVFE-PVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSRE 482
Cdd:cd03237 78 VrdlLSSITKDFYTHPYFktEIAKPLQI-----EQILDrEVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRL 152
|
170 180 190
....*....|....*....|....*....|....*....
gi 1226689869 483 ALENALSDF----PGTIISVSHDRYFINRFAEKVWVLDG 517
Cdd:cd03237 153 MASKVIRRFaennEKTAFVVEHDIIMIDYLADRLIVFEG 191
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
340-517 |
1.11e-18 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 83.74 E-value: 1.11e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 340 DRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLigvekpdAGVIRWGTGvdlgyydqhQSELHENKTVLdevwdrF-P 418
Cdd:cd03223 13 GRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRAL-------AGLWPWGSG---------RIGMPEGEDLL------FlP 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 419 RmEQYEVRGAL-GLFLFTGDEVfepvstLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPGTIIS 497
Cdd:cd03223 71 Q-RPYLPLGTLrEQLIYPWDDV------LSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQLLKELGITVIS 143
|
170 180
....*....|....*....|
gi 1226689869 498 VSHdRYFINRFAEKVWVLDG 517
Cdd:cd03223 144 VGH-RPSLWKFHDRVLDLDG 162
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
331-521 |
1.18e-18 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 84.62 E-value: 1.18e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 331 TEGLSKGYGDRI-LFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDL---------GYYDQH- 399
Cdd:cd03226 2 IENISFSYKKGTeILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLN-GKPIkakerrksiGYVMQDv 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 400 QSELHENkTVLDEVWDRFPRMEQY--EVRGALGLF-LFTGDEVfEPVStLSGGEKGRVALTELMLRKDNVLLLDEPTNHL 476
Cdd:cd03226 81 DYQLFTD-SVREELLLGLKELDAGneQAETVLKDLdLYALKER-HPLS-LSGGQKQRLAIAAALLSGKDLLIFDEPTSGL 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1226689869 477 DMDSREALENALSDFPG---TIISVSHDRYFINRFAEKVWVLDGNEIK 521
Cdd:cd03226 158 DYKNMERVGELIRELAAqgkAVIVITHDYEFLAKVCDRVLLLANGAIV 205
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
332-523 |
1.20e-18 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 85.33 E-value: 1.20e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDR----ILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDL-------------- 393
Cdd:cd03258 5 KNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVD-GTDLtllsgkelrkarrr 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 394 -GYYDQHQSeLHENKTVLD------EVWdRFPRMEQYE-VRGALGLFLFTGDEVFEPvSTLSGGEKGRVALTELMLRKDN 465
Cdd:cd03258 84 iGMIFQHFN-LLSSRTVFEnvalplEIA-GVPKAEIEErVLELLELVGLEDKADAYP-AQLSGGQKQRVGIARALANNPK 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 466 VLLLDEPTNHLDMDSREALENALSD----FPGTIISVSHDRYFINRFAEKVWVLDGNEIKEY 523
Cdd:cd03258 161 VLLCDEATSALDPETTQSILALLRDinreLGLTIVLITHEMEVVKRICDRVAVMEKGEVVEE 222
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
332-521 |
1.26e-18 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 84.94 E-value: 1.26e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGdRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVD-----------LGYYDQHQ 400
Cdd:cd03264 4 ENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRID-GQDvlkqpqklrrrIGYLPQEF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 SeLHENKTV---------LDEVWDRFPRMEQYEVRGALGLflftGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDE 471
Cdd:cd03264 82 G-VYPNFTVrefldyiawLKGIPSKEVKARVDEVLELVNL----GDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 472 PTNHLDMDSREALENALSDF-PGTIISVS-HDRYFINRFAEKVWVLDGNEIK 521
Cdd:cd03264 157 PTAGLDPEERIRFRNLLSELgEDRIVILStHIVEDVESLCNQVAVLNKGKLV 208
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
332-520 |
2.05e-18 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 84.86 E-value: 2.05e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDL---------------GYY 396
Cdd:cd03261 4 RGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLID-GEDIsglseaelyrlrrrmGML 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 397 DQhQSELHENKTVLDEVwdRFP-----RMEQYEVR-------GALGLflfTGDEVFEPvSTLSGGEKGRVALTE-LMLRK 463
Cdd:cd03261 83 FQ-SGALFDSLTVFENV--AFPlrehtRLSEEEIReivleklEAVGL---RGAEDLYP-AELSGGMKKRVALARaLALDP 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 464 DnVLLLDEPTNHLD---MDSREALENALSDFPG-TIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:cd03261 156 E-LLLYDEPTAGLDpiaSGVIDDLIRSLKKELGlTSIMVTHDLDTAFAIADRIAVLYDGKI 215
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
6-236 |
2.62e-18 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 82.29 E-value: 2.62e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 6 LQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmqkglrigylaqqgeltgeetvle 85
Cdd:cd00267 2 IENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEI------------------------- 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 86 tlesvfepqrrmeaelrsleqemaesgsdpealRILGgkydtltREFERSNGYGWRSSVQGVlaglelreFQdmktglLS 165
Cdd:cd00267 57 ---------------------------------LIDG-------KDIAKLPLEELRRRIGYV--------PQ------LS 82
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 166 GGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG---AVLVISHDRYFLDRVCGRMAELLLG 236
Cdd:cd00267 83 GGQRQRVALARALLLNPDLLLLDEPTSGLDPASRERLLELLRELAEegrTVIIVTHDPELAELAADRVIVLKDG 156
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
12-219 |
2.68e-18 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 83.44 E-value: 2.68e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 12 SFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQQGE------LTGEETVLE 85
Cdd:NF040873 1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVAYVPQRSEvpdslpLTVRDLVAM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 86 TLESVFEPQRRMEAELRSLEQEmaesgsdpeALRILGgkydtltrefersngygwrssvqgvLAGLELREFQDmktglLS 165
Cdd:NF040873 81 GRWARRGLWRRLTRDDRAAVDD---------ALERVG-------------------------LADLAGRQLGE-----LS 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 166 GGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG---AVLVISHD 219
Cdd:NF040873 122 GGQRQRALLAQGLAQEADLLLLDEPTTGLDAESRERIIALLAEEHArgaTVVVVTHD 178
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
4-226 |
2.77e-18 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 84.08 E-value: 2.77e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFG----THEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM---------QKGL---- 66
Cdd:cd03255 1 IELKNLSKTYGgggeKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVdgtdisklsEKELaafr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 67 --RIGYLAQQGELTGEETVLETLE--SVFEPQRRMEAELRSLeqemaesgsdpEALRILGgkydtltrefersngygwrs 142
Cdd:cd03255 81 rrHIGFVFQSFNLLPDLTALENVElpLLLAGVPKKERRERAE-----------ELLERVG-------------------- 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 143 svqgvlagleLREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKS----IAWLEEYLAAFHGAVLVISH 218
Cdd:cd03255 130 ----------LGDRLNHYPSELSGGQQQRVAIARALANDPKIILADEPTGNLDSETgkevMELLRELNKEAGTTIVVVTH 199
|
250
....*....|.
gi 1226689869 219 DRYFL---DRV 226
Cdd:cd03255 200 DPELAeyaDRI 210
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
329-500 |
3.27e-18 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 83.42 E-value: 3.27e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRwgtgvDLGYYDQHQSEL----- 403
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEIT-----FDGKSYQKNIEAlrrig 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 404 --------------HENKTVLDEVWdRFPRMEQYEVRGALGLflftGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLL 469
Cdd:cd03268 76 alieapgfypnltaRENLRLLARLL-GIRKKRIDEVLDVVGL----KDSAKKKVKGFSLGMKQRLGIALALLGNPDLLIL 150
|
170 180 190
....*....|....*....|....*....|....*
gi 1226689869 470 DEPTNHLD----MDSREALENaLSDFPGTIISVSH 500
Cdd:cd03268 151 DEPTNGLDpdgiKELRELILS-LRDQGITVLISSH 184
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
3-239 |
3.43e-18 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 83.94 E-value: 3.43e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGT----HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM---------QKGL--- 66
Cdd:COG1136 4 LLELRNLTKSYGTgegeVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIdgqdisslsERELarl 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 67 ---RIGYLAQQGELTGEETVLETLESVFEPQRRMEAELRsleqEMAEsgsdpEALRILGgkydtltrefersngygwrss 143
Cdd:COG1136 84 rrrHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERR----ERAR-----ELLERVG--------------------- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 144 vqgvlagleLREFQDMKTGLLSGGERTRLCLGRmlltepdllllDEPTNHLDLKS----IAWLEEYLAAFHGAVLVISHD 219
Cdd:COG1136 134 ---------LGDRLDHRPSQLSGGQQQRVAIARalvnrpklilaDEPTGNLDSKTgeevLELLRELNRELGTTIVMVTHD 204
|
250 260
....*....|....*....|
gi 1226689869 220 RYFLDRvCGRMAELLLGNVE 239
Cdd:COG1136 205 PELAAR-ADRVIRLRDGRIV 223
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
332-516 |
3.51e-18 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 86.35 E-value: 3.51e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDL-----------GYYDQHQ 400
Cdd:COG1118 6 RNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLN-GRDLftnlpprerrvGFVFQHY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 SeLHENKTVLD------EVWDRFPRMEQYEVRGALGLFLFTGdevFE---PvSTLSGGEKGRVALTELMLRKDNVLLLDE 471
Cdd:COG1118 85 A-LFPHMTVAEniafglRVRPPSKAEIRARVEELLELVQLEG---LAdryP-SQLSGGQRQRVALARALAVEPEVLLLDE 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 472 PTNHLDMDSREALE----NALSDFPGTIISVSHDR---YfinRFAEKVWVLD 516
Cdd:COG1118 160 PFGALDAKVRKELRrwlrRLHDELGGTTVFVTHDQeeaL---ELADRVVVMN 208
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
329-503 |
5.29e-18 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 83.91 E-value: 5.29e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQSELH---- 404
Cdd:PRK11231 3 LRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLG-DKPISMLSSRQLARRlall 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 405 -------ENKTVLDEV----------WDRFPRMEQYEVRGALGLflfTGDEVF--EPVSTLSGGEKGRVALTELMLRKDN 465
Cdd:PRK11231 82 pqhhltpEGITVRELVaygrspwlslWGRLSAEDNARVNQAMEQ---TRINHLadRRLTDLSGGQRQRAFLAMVLAQDTP 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1226689869 466 VLLLDEPTNHLDMdSREA----LENALSDFPGTIISVSHD-----RY 503
Cdd:PRK11231 159 VVLLDEPTTYLDI-NHQVelmrLMRELNTQGKTVVTVLHDlnqasRY 204
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
329-473 |
5.59e-18 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 83.25 E-value: 5.59e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGD-RILFrDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQ------- 400
Cdd:cd03224 1 LEVENLNAGYGKsQILF-GVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFD-GRDITGLPPHEraragig 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 ---------SEL--HEN-------------KTVLDEVWDRFPRMEqyEVRGALGlflftgdevfepvSTLSGGEKGRVAL 456
Cdd:cd03224 79 yvpegrrifPELtvEENlllgayarrrakrKARLERVYELFPRLK--ERRKQLA-------------GTLSGGEQQMLAI 143
|
170
....*....|....*..
gi 1226689869 457 TELMLRKDNVLLLDEPT 473
Cdd:cd03224 144 ARALMSRPKLLLLDEPS 160
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
4-230 |
6.00e-18 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 83.15 E-value: 6.00e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSF-GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmqkglRIGylaqqGELTGEET 82
Cdd:COG1122 1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEV------LVD-----GKDITKKN 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 VLETLESV-----------FEPqrrmeaelrSLEQEMAESgsdpeaLRILGgkydtLTREfERsngygwRSSVQGVLAGL 151
Cdd:COG1122 70 LRELRRKVglvfqnpddqlFAP---------TVEEDVAFG------PENLG-----LPRE-EI------RERVEEALELV 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 152 ELREFQDMKTGLLSGGERTRLCLGR----------MlltepdllllDEPTNHLDLKSIAWLEEYLAAFHGA---VLVISH 218
Cdd:COG1122 123 GLEHLADRPPHELSGGQKQRVAIAGvlamepevlvL----------DEPTAGLDPRGRRELLELLKRLNKEgktVIIVTH 192
|
250
....*....|..
gi 1226689869 219 DRYFLDRVCGRM 230
Cdd:COG1122 193 DLDLVAELADRV 204
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
328-500 |
6.22e-18 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 82.61 E-value: 6.22e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW-GTGVDLGY------YDQHQ 400
Cdd:PRK13539 2 MLEGEDLACVRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLdGGDIDDPDvaeachYLGHR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 SELHENKTVLD--EVWDRFPRMEQYEVRGAL---GLflftgDEVFE-PVSTLSGGEKGRVALTELMLRKDNVLLLDEPTN 474
Cdd:PRK13539 82 NAMKPALTVAEnlEFWAAFLGGEELDIAAALeavGL-----APLAHlPFGYLSAGQKRRVALARLLVSNRPIWILDEPTA 156
|
170 180
....*....|....*....|....*....
gi 1226689869 475 HLDMDSREALENALSDF---PGTIISVSH 500
Cdd:PRK13539 157 ALDAAAVALFAELIRAHlaqGGIVIAATH 185
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
331-523 |
7.24e-18 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 83.00 E-value: 7.24e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 331 TEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCL-----IGVEKPDAGVIRWGtGVDLGYYDQHQSELHE 405
Cdd:cd03260 3 LRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLnrlndLIPGAPDEGEVLLD-GKDIYDLDVDVLELRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 ------------NKTVLDEV---------WDRFPRMEqyEVRGAL---GLFlftgDEVFEP--VSTLSGGEKGRVALTEL 459
Cdd:cd03260 82 rvgmvfqkpnpfPGSIYDNVayglrlhgiKLKEELDE--RVEEALrkaALW----DEVKDRlhALGLSGGQQQRLCLARA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 460 MLRKDNVLLLDEPTNHLDMDSREALENALSDF--PGTIISVSHDRYFINRFAEKVWVLDGNEIKEY 523
Cdd:cd03260 156 LANEPEVLLLDEPTSALDPISTAKIEELIAELkkEYTIVIVTHNMQQAARVADRTAFLLNGRLVEF 221
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
5-219 |
7.60e-18 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 81.71 E-value: 7.60e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 5 ALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmqkglrigYLAQQgeltgeetvl 84
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEI---------LLDGK---------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 85 etleSVFEPQRRMEAELRSLEqemaesgsdPEALRILGgkydtltrefersngygwrssvqgvLAGLELREFQDmktglL 164
Cdd:cd03214 62 ----DLASLSPKELARKIAYV---------PQALELLG-------------------------LAHLADRPFNE-----L 98
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 165 SGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG----AVLVISHD 219
Cdd:cd03214 99 SGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQIELLELLRRLARergkTVVMVLHD 157
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
332-501 |
7.76e-18 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 82.69 E-value: 7.76e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGV--DLGYYDQHQSELHENKTV 409
Cdd:cd03301 4 ENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDvtDLPPKDRDIAMVFQNYAL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 410 ldevwdrFPRMEQYEvRGALGLFL--FTGDEVFEPV-----------------STLSGGEKGRVALTELMLRKDNVLLLD 470
Cdd:cd03301 84 -------YPHMTVYD-NIAFGLKLrkVPKDEIDERVrevaellqiehlldrkpKQLSGGQRQRVALGRAIVREPKVFLMD 155
|
170 180 190
....*....|....*....|....*....|....*
gi 1226689869 471 EPTNHLDMDSREALENALSDF----PGTIISVSHD 501
Cdd:cd03301 156 EPLSNLDAKLRVQMRAELKRLqqrlGTTTIYVTHD 190
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
4-73 |
8.50e-18 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 85.20 E-value: 8.50e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-----------SMQKgLRIGYLA 72
Cdd:COG1118 3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIvlngrdlftnlPPRE-RRVGFVF 81
|
.
gi 1226689869 73 Q 73
Cdd:COG1118 82 Q 82
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
10-81 |
8.89e-18 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 83.21 E-value: 8.89e-18
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 10 KKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMqKGlRIGYLAQ-----QGELTGEE 81
Cdd:COG1134 33 RTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEV-NG-RVSALLElgagfHPELTGRE 107
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
8-231 |
1.49e-17 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 81.57 E-value: 1.49e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 8 DVKKSFGTHEvLKsVSFTLqDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM--------QKGL-------RIGYLA 72
Cdd:cd03297 5 DIEKRLPDFT-LK-IDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLngtvlfdsRKKInlppqqrKIGLVF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 73 QQGELTGEETVLETLESVFEPQRRMEAelrsleqemaesgsdpealrilggkydtltrefersngygwRSSVQGVLAGLE 152
Cdd:cd03297 82 QQYALFPHLNVRENLAFGLKRKRNRED-----------------------------------------RISVDELLDLLG 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 153 LREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD----LKSIAWLEEYLAAFHGAVLVISHDRYFLDRVCG 228
Cdd:cd03297 121 LDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDralrLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLAD 200
|
...
gi 1226689869 229 RMA 231
Cdd:cd03297 201 RIV 203
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
332-501 |
1.79e-17 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 82.44 E-value: 1.79e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGY----GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW------GTGVDLGYYDQHQS 401
Cdd:COG1116 11 RGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVdgkpvtGPGPDRGVVFQEPA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 402 eLHENKTVLDEVW-----DRFPRMEQYE-VRGALGLFLFTGdevFE---PvSTLSGGEKGRVAL--TeLMLRKDnVLLLD 470
Cdd:COG1116 91 -LLPWLTVLDNVAlglelRGVPKAERRErARELLELVGLAG---FEdayP-HQLSGGMRQRVAIarA-LANDPE-VLLMD 163
|
170 180 190
....*....|....*....|....*....|....*
gi 1226689869 471 EPTNHLDMDSREALENAL----SDFPGTIISVSHD 501
Cdd:COG1116 164 EPFGALDALTRERLQDELlrlwQETGKTVLFVTHD 198
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
332-518 |
2.01e-17 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 81.38 E-value: 2.01e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGD-----RILfRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQSELHEN 406
Cdd:cd03255 4 KNLSKTYGGggekvQAL-KGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVD-GTDISKLSEKELAAFRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 407 K---------------TVLDEVwdRFP------RMEQYEVR-----GALGLflftGDEVFEPVSTLSGGEKGRVALTELM 460
Cdd:cd03255 82 RhigfvfqsfnllpdlTALENV--ELPlllagvPKKERRERaeellERVGL----GDRLNHYPSELSGGQQQRVAIARAL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 461 LRKDNVLLLDEPTNHLDMDSREALENALSDFPG----TIISVSHDRYFINRFAEKVWVLDGN 518
Cdd:cd03255 156 ANDPKIILADEPTGNLDSETGKEVMELLRELNKeagtTIVVVTHDPELAEYADRIIELRDGK 217
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
3-71 |
2.44e-17 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 82.85 E-value: 2.44e-17
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ-------KGLRIGYL 71
Cdd:COG4152 1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDgepldpeDRRRIGYL 76
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
351-515 |
2.60e-17 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 81.81 E-value: 2.60e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 351 VRAGDRIALIGDNGTGKSTLLQCLIGVEkPDAGVIRWGtGVDLGYYD------------QHQS-----------ELH-EN 406
Cdd:COG4138 19 VNAGELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLN-GRPLSDWSaaelarhraylsQQQSppfampvfqylALHqPA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 407 KTVLDEVWDRFprmeqYEVRGALGLflftGDEVFEPVSTLSGGEKGRVALTELML---RKDN----VLLLDEPTNHLDMD 479
Cdd:COG4138 97 GASSEAVEQLL-----AQLAEALGL----EDKLSRPLTQLSGGEWQRVRLAAVLLqvwPTINpegqLLLLDEPMNSLDVA 167
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1226689869 480 SREALENALSDFP---GTIISVSHDryfIN---RFAEKVWVL 515
Cdd:COG4138 168 QQAALDRLLRELCqqgITVVMSSHD---LNhtlRHADRVWLL 206
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
12-237 |
2.79e-17 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 80.76 E-value: 2.79e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 12 SFGTH---EVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM------QKGLR--IGYLAQ--QGELT 78
Cdd:cd03226 6 SFSYKkgtEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLngkpikAKERRksIGYVMQdvDYQLF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 79 GEetvletleSVFEpqrrmeaELRsleqemaesgsdpEALRILGGKYDTltrefersngygwrssVQGVLAGLELREFQD 158
Cdd:cd03226 86 TD--------SVRE-------ELL-------------LGLKELDAGNEQ----------------AETVLKDLDLYALKE 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 159 MKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD---LKSIAWLEEYLAAFHGAVLVISHDRYFLDRVCGRmaELLL 235
Cdd:cd03226 122 RHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDyknMERVGELIRELAAQGKAVIVITHDYEFLAKVCDR--VLLL 199
|
..
gi 1226689869 236 GN 237
Cdd:cd03226 200 AN 201
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
3-238 |
3.23e-17 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 81.01 E-value: 3.23e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSF----GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV------------SMQK-- 64
Cdd:cd03257 1 LLEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIifdgkdllklsrRLRKir 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 65 GLRIGYLAQQG------ELTGEETVLETLESVFePQRRMEAELRSLEQEMAESGSDPEALRilggKYdtltrefersngy 138
Cdd:cd03257 81 RKEIQMVFQDPmsslnpRMTIGEQIAEPLRIHG-KLSKKEARKEAVLLLLVGVGLPEEVLN----RY------------- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 139 gwrssvqgvlaglelrEFQdmktglLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKS----IAWLEEYLAAFHGAVL 214
Cdd:cd03257 143 ----------------PHE------LSGGQRQRVAIARALALNPKLLIADEPTSALDVSVqaqiLDLLKKLQEELGLTLL 200
|
250 260
....*....|....*....|....
gi 1226689869 215 VISHDRYFLDRVCGRMAELLLGNV 238
Cdd:cd03257 201 FITHDLGVVAKIADRVAVMYAGKI 224
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
4-63 |
4.14e-17 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 79.01 E-value: 4.14e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ 63
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVD 60
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
4-200 |
5.22e-17 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 80.66 E-value: 5.22e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQK------------GLRIGYL 71
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGqditklpmhkraRLGIGYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 72 AQQGELTGEETVLETLESVFEPQRRMEAELRSleqemaesgsdpealrilggKYDTLTREFersngygwrssvqgvlagl 151
Cdd:cd03218 81 PQEASIFRKLTVEENILAVLEIRGLSKKEREE--------------------KLEELLEEF------------------- 121
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1226689869 152 ELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIA 200
Cdd:cd03218 122 HITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEPFAGVDPIAVQ 170
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-62 |
5.46e-17 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 82.81 E-value: 5.46e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM 62
Cdd:COG3839 1 MASLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILI 62
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
326-517 |
6.07e-17 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 80.09 E-value: 6.07e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 326 DDVLMTEGLSKGYGD-----RILfRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQ 400
Cdd:COG1136 2 SPLLELRNLTKSYGTgegevTAL-RGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLID-GQDISSLSERE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 ---------------SELHENKTVLDEVW-----DRFPRMEQ----YEVRGALGLflftGDEVFEPVSTLSGGEKGRVAL 456
Cdd:COG1136 80 larlrrrhigfvfqfFNLLPELTALENVAlplllAGVSRKERreraRELLERVGL----GDRLDHRPSQLSGGQQQRVAI 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 457 TELMLRKDNVLLLDEPTNHLDMDSREALENALSDF---PG-TIISVSHDRYFINRFAEKVWVLDG 517
Cdd:COG1136 156 ARALVNRPKLILADEPTGNLDSKTGEEVLELLRELnreLGtTIVMVTHDPELAARADRVIRLRDG 220
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
332-523 |
6.92e-17 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 80.24 E-value: 6.92e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILF----RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQSELHENK 407
Cdd:cd03257 5 KNLSVSFPTGGGSvkalDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFD-GKDLLKLSRRLRKIRRKE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 408 ----------------TVLD------EVWDRFPRMEQYEVRGALGLFLFTGDEVFE---PvSTLSGGEKGRVALTELMLR 462
Cdd:cd03257 84 iqmvfqdpmsslnprmTIGEqiaeplRIHGKLSKKEARKEAVLLLLVGVGLPEEVLnryP-HELSGGQRQRVAIARALAL 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 463 KDNVLLLDEPTNHLDMDSREALENALSD----FPGTIISVSHDRYFINRFAEKVWVLDGNEIKEY 523
Cdd:cd03257 163 NPKLLIADEPTSALDVSVQAQILDLLKKlqeeLGLTLLFITHDLGVVAKIADRVAVMYAGKIVEE 227
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
4-231 |
8.51e-17 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 78.38 E-value: 8.51e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmqkglrigylaqqgELTGEEtv 83
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSI---------------LIDGED-- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 84 LETLESVFEPQRRmeaelrsleqemaesgsdpeALRILggkydtltreFERSNGYGWRSSVQGVLAGlelrefqdmktgl 163
Cdd:cd03229 64 LTDLEDELPPLRR--------------------RIGMV----------FQDFALFPHLTVLENIALG------------- 100
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 164 LSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG----AVLVISHDRYFLDRVCGRMA 231
Cdd:cd03229 101 LSGGQQQRVALARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAqlgiTVVLVTHDLDEAARLADRVV 172
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
332-522 |
8.69e-17 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 80.08 E-value: 8.69e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWG----TGVDL-----GYYDQHQSe 402
Cdd:cd03296 6 RNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGgedaTDVPVqernvGFVFQHYA- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 403 LHENKTVLDEV---------WDRFPRME-QYEVRGALGLFLFTGDEVFEPvSTLSGGEKGRVALTELMLRKDNVLLLDEP 472
Cdd:cd03296 85 LFRHMTVFDNVafglrvkprSERPPEAEiRAKVHELLKLVQLDWLADRYP-AQLSGGQRQRVALARALAVEPKVLLLDEP 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 473 TNHLDMDSREALENAL----SDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKE 522
Cdd:cd03296 164 FGALDAKVRKELRRWLrrlhDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQ 217
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
332-512 |
8.71e-17 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 80.30 E-value: 8.71e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGD-RILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW-GTGV-------------DLGYY 396
Cdd:cd03256 4 ENLSKTYPNgKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIdGTDInklkgkalrqlrrQIGMI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 397 DQHQSeLHENKTVLDEV--------------WDRFPRMEQYEVRGAL---GLFlftgDEVFEPVSTLSGGEKGRVALTEL 459
Cdd:cd03256 84 FQQFN-LIERLSVLENVlsgrlgrrstwrslFGLFPKEEKQRALAALervGLL----DKAYQRADQLSGGQQQRVAIARA 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 460 MLRKDNVLLLDEPTNHLDMDSREALENALSDFPG----TIISVSHDRYFINRFAEKV 512
Cdd:cd03256 159 LMQQPKLILADEPVASLDPASSRQVMDLLKRINReegiTVIVSLHQVDLAREYADRI 215
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
3-85 |
8.76e-17 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 80.02 E-value: 8.76e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM---------QKGL-----RI 68
Cdd:COG1127 5 MIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVdgqditglsEKELyelrrRI 84
|
90
....*....|....*..
gi 1226689869 69 GYLAQQGELTGEETVLE 85
Cdd:COG1127 85 GMLFQGGALFDSLTVFE 101
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
25-517 |
9.13e-17 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 83.70 E-value: 9.13e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 25 TLQDGERMGLVGVNGSGKSTIMKIIAGletadsgtvSMQKGLrigylaqqGELTGE---ETVLE-----TLESVFEpqRR 96
Cdd:PRK13409 95 IPKEGKVTGILGPNGIGKTTAVKILSG---------ELIPNL--------GDYEEEpswDEVLKrfrgtELQNYFK--KL 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 97 MEAELR-SLEQEMAEsgsdpEALRILGGKY-DTLTREFERSNgygwrssVQGVLAGLELREFQDMKTGLLSGGERTRLCL 174
Cdd:PRK13409 156 YNGEIKvVHKPQYVD-----LIPKVFKGKVrELLKKVDERGK-------LDEVVERLGLENILDRDISELSGGELQRVAI 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 175 GRMLLTEPDLLLLDEPTNHLDLK---SIAWLEEYLAAFHgAVLVISHDRYFLDrvcgrmaeLLLGNVE-TY--SGNYTey 248
Cdd:PRK13409 224 AAALLRDADFYFFDEPTSYLDIRqrlNVARLIRELAEGK-YVLVVEHDLAVLD--------YLADNVHiAYgePGAYG-- 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 249 leKRTTVYENRmrawklqqkeiarqEAIIAMYRRFNKEKSIRIanskqkRLDMVERLEKPEDESTirfrfetrrrTGDDV 328
Cdd:PRK13409 293 --VVSKPKGVR--------------VGINEYLKGYLPEENMRI------RPEPIEFEERPPRDES----------ERETL 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDrilFRdLKMH---VRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtgVDLGYYDQHQSELHE 405
Cdd:PRK13409 341 VEYPDLTKKLGD---FS-LEVEggeIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE--LKISYKPQYIKPDYD 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 nKTV---LDEVWDRF-PRMEQYEVRGALGLflftgDEVFE-PVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDS 480
Cdd:PRK13409 415 -GTVedlLRSITDDLgSSYYKSEIIKPLQL-----ERLLDkNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQ 488
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 1226689869 481 R----EALENALSDFPGTIISVSHDRYFINRFAEKVWVLDG 517
Cdd:PRK13409 489 RlavaKAIRRIAEEREATALVVDHDIYMIDYISDRLMVFEG 529
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
332-517 |
9.49e-17 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 77.85 E-value: 9.49e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQSElhenktvld 411
Cdd:cd03216 4 RGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVD-GKEVSFASPRDAR--------- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 412 evwdrfprmeqyevrgALGLflftgdevfEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDF 491
Cdd:cd03216 74 ----------------RAGI---------AMVYQLSVGERQMVEIARALARNARLLILDEPTAALTPAEVERLFKVIRRL 128
|
170 180 190
....*....|....*....|....*....|
gi 1226689869 492 PG---TIISVSHDRYFINRFAEKVWVL-DG 517
Cdd:cd03216 129 RAqgvAVIFISHRLDEVFEIADRVTVLrDG 158
|
|
| ABC_tran_Xtn |
pfam12848 |
ABC transporter; This domain is an extension of some members of pfam00005 and other ... |
231-312 |
1.10e-16 |
|
ABC transporter; This domain is an extension of some members of pfam00005 and other ABC-transporter families.
Pssm-ID: 463731 [Multi-domain] Cd Length: 85 Bit Score: 75.30 E-value: 1.10e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 231 AELLLGNVETYSGNYTEYLEKRTTVYENRMRAWKLQQKEIARQEAIIamyRRFN-KEKSIRIANSKQKRLDMVERLEKPE 309
Cdd:pfam12848 1 VELERGKLTTYKGNYSTFLEQKEERLEQQEKAYEKQQKEIKKLEEFI---DRFRaKASKAKQAQSRIKALEKMERIEKPE 77
|
...
gi 1226689869 310 DES 312
Cdd:pfam12848 78 RDK 80
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
351-515 |
1.12e-16 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 79.98 E-value: 1.12e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 351 VRAGDRIALIGDNGTGKSTLLQCLIGVeKPDAGVIRWG-------TGVDL----GYYDQHQS-----------ELHE-NK 407
Cdd:PRK03695 19 VRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAgqpleawSAAELarhrAYLSQQQTppfampvfqylTLHQpDK 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 408 TVLDEVWDRFprmeqYEVRGALGLflftGDEVFEPVSTLSGGEKGRVALTELML---RKDN----VLLLDEPTNHLDMDS 480
Cdd:PRK03695 98 TRTEAVASAL-----NEVAEALGL----DDKLGRSVNQLSGGEWQRVRLAAVVLqvwPDINpagqLLLLDEPMNSLDVAQ 168
|
170 180 190
....*....|....*....|....*....|....*...
gi 1226689869 481 REALENALSDFPGTIISV---SHDRYFINRFAEKVWVL 515
Cdd:PRK03695 169 QAALDRLLSELCQQGIAVvmsSHDLNHTLRHADRVWLL 206
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
4-219 |
1.32e-16 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 79.40 E-value: 1.32e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ----KGLRIGYLAQQG---- 75
Cdd:cd03219 1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDgediTGLPPHEIARLGigrt 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 76 ----ELTGEETVLETLESVFEPQRRMEAELRSLEQEMAEsgSDPEALRILggkydtltrEFersngygwrssvqgvlagL 151
Cdd:cd03219 81 fqipRLFPELTVLENVMVAAQARTGSGLLLARARREERE--ARERAEELL---------ER------------------V 131
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 152 ELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPT---NHLDLKSIAWLEEYLAAFHGAVLVISHD 219
Cdd:cd03219 132 GLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAaglNPEETEELAELIRELRERGITVLLVEHD 202
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
329-489 |
1.65e-16 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 78.30 E-value: 1.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVDLGYYDQHQSEL----H 404
Cdd:cd03231 1 LEADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIARGLlylgH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 405 EN--KTVLDEV-----WDRFPRMEQyeVRGALGLFLFTGdevFE--PVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNH 475
Cdd:cd03231 81 APgiKTTLSVLenlrfWHADHSDEQ--VEEALARVGLNG---FEdrPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTA 155
|
170
....*....|....
gi 1226689869 476 LDMDSREALENALS 489
Cdd:cd03231 156 LDKAGVARFAEAMA 169
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
4-238 |
2.71e-16 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 78.32 E-value: 2.71e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHE--VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-----SMQKGL-----RIGYL 71
Cdd:cd03263 1 LQIRNLTKTYKKGTkpAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAyingySIRTDRkaarqSLGYC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 72 AQQGELTGEETVLETLesvfepqrRMEAELRSLEQEMAesgsdpealrilggkydtltrefersngygwRSSVQGVLAGL 151
Cdd:cd03263 81 PQFDALFDELTVREHL--------RFYARLKGLPKSEI-------------------------------KEEVELLLRVL 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 152 ELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD--LKSIAW--LEEYLAafHGAVLVISHDRYFLDRVC 227
Cdd:cd03263 122 GLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGLDpaSRRAIWdlILEVRK--GRSIILTTHSMDEAEALC 199
|
250
....*....|.
gi 1226689869 228 GRMAELLLGNV 238
Cdd:cd03263 200 DRIAIMSDGKL 210
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1-60 |
3.65e-16 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 81.60 E-value: 3.65e-16
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:COG1129 2 EPLLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEI 61
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
1-240 |
4.46e-16 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 78.58 E-value: 4.46e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTH---------EVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkGLRIGYL 71
Cdd:PRK10419 1 MTLLNVSGLSHHYAHGglsgkhqhqTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWR-GEPLAKL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 72 --AQQGELTGE-ETVLETLESVFEPQRRMEAELRsleqemaesgsdpEALRILggkydTLTREFERsngygwRSSVQGVL 148
Cdd:PRK10419 80 nrAQRKAFRRDiQMVFQDSISAVNPRKTVREIIR-------------EPLRHL-----LSLDKAER------LARASEML 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 149 AGLELR-EFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDL----KSIAWLEEYLAAFHGAVLVISHDRYFL 223
Cdd:PRK10419 136 RAVDLDdSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLDLvlqaGVIRLLKKLQQQFGTACLFITHDLRLV 215
|
250
....*....|....*...
gi 1226689869 224 DRVCGRMAELLLGN-VET 240
Cdd:PRK10419 216 ERFCQRVMVMDNGQiVET 233
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
4-257 |
7.86e-16 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 81.03 E-value: 7.86e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVkkSFG----THEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM---------QKGLR--I 68
Cdd:COG2274 474 IELENV--SFRypgdSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIdgidlrqidPASLRrqI 551
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 69 GYLAQQGEL-TGeeTVLETLeSVFEPQRRMEaELRsleqemaesgsdpEALRILG---------GKYDTLTREfersNGY 138
Cdd:COG2274 552 GVVLQDVFLfSG--TIRENI-TLGDPDATDE-EII-------------EAARLAGlhdfiealpMGYDTVVGE----GGS 610
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 139 GwrssvqgvlaglelrefqdmktglLSGGERTRLCLGR----------MlltepdllllDEPTNHLDLKSIAWLEEYLAA 208
Cdd:COG2274 611 N------------------------LSGGQRQRLAIARallrnpriliL----------DEATSALDAETEAIILENLRR 656
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 209 FHG--AVLVISH--------DR-YFLDRvcGRMAElllgnvetySGNYTEYLEKRTTVYE 257
Cdd:COG2274 657 LLKgrTVIIIAHrlstirlaDRiIVLDK--GRIVE---------DGTHEELLARKGLYAE 705
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-74 |
7.95e-16 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 77.82 E-value: 7.95e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSF----GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM------QKGLRIGY 70
Cdd:COG1116 5 APALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVdgkpvtGPGPDRGV 84
|
....
gi 1226689869 71 LAQQ 74
Cdd:COG1116 85 VFQE 88
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
325-516 |
1.11e-15 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 77.39 E-value: 1.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 325 GDDVLMTEGLSKGYGD-RILfRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQ--- 400
Cdd:COG0411 1 SDPLLEVRGLTKRFGGlVAV-DDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFD-GRDITGLPPHRiar 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 ---------SELHENKTVLDEV---------------WDRFPRMEQYEVR---------GALGLflftGDEVFEPVSTLS 447
Cdd:COG0411 79 lgiartfqnPRLFPELTVLENVlvaaharlgrgllaaLLRLPRARREEREareraeellERVGL----ADRADEPAGNLS 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 448 GGEKGRV--ALTeLMLRKDnVLLLDEPT---NHLDMDSREALENALSDFPG-TIISVSHDRYFINRFAEKVWVLD 516
Cdd:COG0411 155 YGQQRRLeiARA-LATEPK-LLLLDEPAaglNPEETEELAELIRRLRDERGiTILLIEHDMDLVMGLADRIVVLD 227
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
332-501 |
1.31e-15 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 77.08 E-value: 1.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVDLGYYDQhqsELHENKTVLD 411
Cdd:PRK09544 8 ENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKLRIGYVPQ---KLYLDTTLPL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 412 EVwDRFPRMEQYEVRGALGLFL---FTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREAL---- 484
Cdd:PRK09544 85 TV-NRFLRLRPGTKKEDILPALkrvQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALydli 163
|
170
....*....|....*..
gi 1226689869 485 ENALSDFPGTIISVSHD 501
Cdd:PRK09544 164 DQLRRELDCAVLMVSHD 180
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
332-502 |
1.54e-15 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 78.60 E-value: 1.54e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWG----TGV-----DLGY----YDq 398
Cdd:COG3842 9 ENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDgrdvTGLppekrNVGMvfqdYA- 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 399 hqseLHENKTVLDEV-----WDRFPRMEQYE-VRGALGLflfTGDEVFE--PVSTLSGGEKGRVALTELMLRKDNVLLLD 470
Cdd:COG3842 88 ----LFPHLTVAENVafglrMRGVPKAEIRArVAELLEL---VGLEGLAdrYPHQLSGGQQQRVALARALAPEPRVLLLD 160
|
170 180 190
....*....|....*....|....*....|....*.
gi 1226689869 471 EPTNHLDMDSREALENALSD----FPGTIISVSHDR 502
Cdd:COG3842 161 EPLSALDAKLREEMREELRRlqreLGITFIYVTHDQ 196
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
4-87 |
1.63e-15 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 75.78 E-value: 1.63e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-------SMQKGLRIGYLAQQGE 76
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVlfdgkplDIAARNRIGYLPEERG 80
|
90
....*....|.
gi 1226689869 77 LTGEETVLETL 87
Cdd:cd03269 81 LYPKMKVIDQL 91
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
338-500 |
2.00e-15 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 76.28 E-value: 2.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 338 YGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAG--VIRWGT---GVDL-------GYYDqhqSELHE 405
Cdd:COG1119 13 RGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGndVRLFGErrgGEDVwelrkriGLVS---PALQL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 ----NKTVLD----------EVWDRFPRMEQYEVRGALGLFlftgdEVFE----PVSTLSGGEKGRValteLMLR---KD 464
Cdd:COG1119 90 rfprDETVLDvvlsgffdsiGLYREPTDEQRERARELLELL-----GLAHladrPFGTLSQGEQRRV----LIARalvKD 160
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1226689869 465 -NVLLLDEPTNHLDMDSREALENALSDFPG----TIISVSH 500
Cdd:COG1119 161 pELLILDEPTAGLDLGARELLLALLDKLAAegapTLVLVTH 201
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
346-520 |
2.43e-15 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 75.14 E-value: 2.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 346 DLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLG--------YYDQH------QSELHENKTVLD 411
Cdd:cd03292 19 GINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRV-NGQDVSdlrgraipYLRRKigvvfqDFRLLPDRNVYE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 412 ------EVWDRFPRMEQYEVRGALGLFLFTGDEVFEPvSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALE 485
Cdd:cd03292 98 nvafalEVTGVPPREIRKRVPAALELVGLSHKHRALP-AELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTTWEIM 176
|
170 180 190
....*....|....*....|....*....|....*...
gi 1226689869 486 NALSDFP---GTIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:cd03292 177 NLLKKINkagTTVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
285-528 |
2.55e-15 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 79.40 E-value: 2.55e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 285 KEKSIRIANSkqkRLDMVERLEKPEDEStiRFRFETRRRTGDDVLMTEGLSKGYGDRILfRDLKMHVRAGDRIALIGDNG 364
Cdd:TIGR01193 437 KLQAARVANN---RLNEVYLVDSEFINK--KKRTELNNLNGDIVINDVSYSYGYGSNIL-SDISLTIKMNSKTTIVGMSG 510
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 365 TGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQSELHEN----------KTVLDE-VWDRFPRMEQYEVRGALGLFL 433
Cdd:TIGR01193 511 SGKSTLAKLLVGFFQARSGEILLN-GFSLKDIDRHTLRQFINylpqepyifsGSILENlLLGAKENVSQDEIWAACEIAE 589
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 434 FTGD----------EVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDM-DSREALENALSDFPGTIISVSHdR 502
Cdd:TIGR01193 590 IKDDienmplgyqtELSEEGSSISGGQKQRIALARALLTDSKVLILDESTSNLDTiTEKKIVNNLLNLQDKTIIFVAH-R 668
|
250 260
....*....|....*....|....*.
gi 1226689869 503 YFINRFAEKVWVLDGNEIKEYlGNYD 528
Cdd:TIGR01193 669 LSVAKQSDKIIVLDHGKIIEQ-GSHD 693
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
333-522 |
2.72e-15 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 77.56 E-value: 2.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 333 GLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVI--------------RWGTGVdLGYYDQ 398
Cdd:PRK13536 46 GVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKItvlgvpvpararlaRARIGV-VPQFDN 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 399 HQSELHENKTVLdeVWDRFPRMEQYEVRGAL-GLFLFTGDE--VFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNH 475
Cdd:PRK13536 125 LDLEFTVRENLL--VFGRYFGMSTREIEAVIpSLLEFARLEskADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTG 202
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 476 LDMDSR----EALENALSDfPGTIISVSHDRYFINRFAEKVWVLD-GNEIKE 522
Cdd:PRK13536 203 LDPHARhliwERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEaGRKIAE 253
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
332-501 |
3.36e-15 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 75.35 E-value: 3.36e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQH--------QS-E 402
Cdd:cd03300 4 ENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLD-GKDITNLPPHkrpvntvfQNyA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 403 LHENKTVLDEVwdRFP-RMEQY-------EVRGALGLFLFTGDEVFEPvSTLSGGEKGRVALTELMLRKDNVLLLDEPTN 474
Cdd:cd03300 83 LFPHLTVFENI--AFGlRLKKLpkaeikeRVAEALDLVQLEGYANRKP-SQLSGGQQQRVAIARALVNEPKVLLLDEPLG 159
|
170 180 190
....*....|....*....|....*....|.
gi 1226689869 475 HLDMDSREALENALSDFPG----TIISVSHD 501
Cdd:cd03300 160 ALDLKLRKDMQLELKRLQKelgiTFVFVTHD 190
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
332-473 |
3.45e-15 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 75.40 E-value: 3.45e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGD-RILfRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQ---------- 400
Cdd:COG0410 7 ENLHAGYGGiHVL-HGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFD-GEDITGLPPHRiarlgigyvp 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 ------SEL--HEN--------------KTVLDEVWDRFPRMEqyEVRGALGlflftgdevfepvSTLSGGEK-----GR 453
Cdd:COG0410 85 egrrifPSLtvEENlllgayarrdraevRADLERVYELFPRLK--ERRRQRA-------------GTLSGGEQqmlaiGR 149
|
170 180
....*....|....*....|
gi 1226689869 454 ValteLMLRKDnVLLLDEPT 473
Cdd:COG0410 150 A----LMSRPK-LLLLDEPS 164
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
332-522 |
3.84e-15 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 78.67 E-value: 3.84e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGY-GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHqsELHEN---- 406
Cdd:COG1132 343 ENVSFSYpGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILID-GVDIRDLTLE--SLRRQigvv 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 407 --KTVL------------------DEVW------------DRFPrmEQYE--V--RGalglflftgdevfepvSTLSGGE 450
Cdd:COG1132 420 pqDTFLfsgtirenirygrpdatdEEVEeaakaaqahefiEALP--DGYDtvVgeRG----------------VNLSGGQ 481
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 451 KGRVALTELMLRKDNVLLLDEPTNHLDMDS----REALENALSDfpGTIISVSHDRYFInRFAEKVWVLDGNEIKE 522
Cdd:COG1132 482 RQRIAIARALLKDPPILILDEATSALDTETealiQEALERLMKG--RTTIVIAHRLSTI-RNADRILVLDDGRIVE 554
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
332-520 |
3.86e-15 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 75.18 E-value: 3.86e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLkmHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQ---SEL-HENK 407
Cdd:COG3840 5 DDLTYRYGDFPLRFDL--TIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWN-GQDLTALPPAErpvSMLfQENN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 408 -----TVLDEV-WDRFPRM-----EQYEVRGAL---GLflfTGDEVFEPvSTLSGGEKGRVALTELMLRKDNVLLLDEPT 473
Cdd:COG3840 82 lfphlTVAQNIgLGLRPGLkltaeQRAQVEQALervGL---AGLLDRLP-GQLSGGQRQRVALARCLVRKRPILLLDEPF 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 474 NHLDMDSRE---ALENALSDFPG-TIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:COG3840 158 SALDPALRQemlDLVDELCRERGlTVLMVTHDPEDAARIADRVLLVADGRI 208
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
339-490 |
4.13e-15 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 74.46 E-value: 4.13e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 339 GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLG-----YYDQ-----HQ----SEL- 403
Cdd:PRK13538 12 DERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQ-GEPIRrqrdeYHQDllylgHQpgikTELt 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 404 -HENKTVL---------DEVWDrfprmeqyevrgALGLFLFTGdevFE--PVSTLSGGEKGRVALTELMLRKDNVLLLDE 471
Cdd:PRK13538 91 aLENLRFYqrlhgpgddEALWE------------ALAQVGLAG---FEdvPVRQLSAGQQRRVALARLWLTRAPLWILDE 155
|
170
....*....|....*....
gi 1226689869 472 PTNHLDMDSREALENALSD 490
Cdd:PRK13538 156 PFTAIDKQGVARLEALLAQ 174
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
341-520 |
5.49e-15 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 74.07 E-value: 5.49e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 341 RILFRDLKMH----VRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQ---------HQSELHENK 407
Cdd:cd03298 7 RFSYGEQPMHfdltFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLIN-GVDVTAAPPadrpvsmlfQENNLFAHL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 408 TVLDEV-WDRFPRM-----EQYEVRGALGLFLFTGDEVFEPvSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSR 481
Cdd:cd03298 86 TVEQNVgLGLSPGLkltaeDRQAIEVALARVGLAGLEKRLP-GELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALR 164
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1226689869 482 EALENALSDFPG----TIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:cd03298 165 AEMLDLVLDLHAetkmTVLMVTHQPEDAKRLAQRVVFLDNGRI 207
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
14-83 |
5.93e-15 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 74.49 E-value: 5.93e-15
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 14 GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKG----LRIGYlAQQGELTGEETV 83
Cdd:cd03220 33 GEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRvsslLGLGG-GFNPELTGRENI 105
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
3-60 |
6.25e-15 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 74.39 E-value: 6.25e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 3 ILALQDVKKSFGTHE----VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:COG4181 8 IIELRGLTKTVGTGAgeltILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTV 69
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
4-110 |
7.64e-15 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 74.05 E-value: 7.64e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGT----HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM------QKGLRIGYLAQ 73
Cdd:cd03293 1 LEVRNVSKTYGGgggaVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVdgepvtGPGPDRGYVFQ 80
|
90 100 110
....*....|....*....|....*....|....*..
gi 1226689869 74 QGELTGEETVLETLESVFEPQRRMEAELRSLEQEMAE 110
Cdd:cd03293 81 QDALLPWLTVLDNVALGLELQGVPKAEARERAEELLE 117
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
299-518 |
9.53e-15 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 77.54 E-value: 9.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 299 LDMVERLekPEDESTIRFRFetrrrtgDDVLMTEGLS-KGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLigv 377
Cdd:COG4178 342 LEAADAL--PEAASRIETSE-------DGALALEDLTlRTPDGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAI--- 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 378 ekpdAGVIRWGTG------------------VDLG------YYDQHQSEL--HENKTVLDEV--------------WDRf 417
Cdd:COG4178 410 ----AGLWPYGSGriarpagarvlflpqrpyLPLGtlrealLYPATAEAFsdAELREALEAVglghlaerldeeadWDQ- 484
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 418 prmeqyevrgalglflftgdevfepvsTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSD-FPG-TI 495
Cdd:COG4178 485 ---------------------------VLSLGEQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQLLREeLPGtTV 537
|
250 260
....*....|....*....|...
gi 1226689869 496 ISVSHdRYFINRFAEKVWVLDGN 518
Cdd:COG4178 538 ISVGH-RSTLAAFHDRVLELTGD 559
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-60 |
1.05e-14 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 75.90 E-value: 1.05e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:COG3842 3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRI 62
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
328-520 |
1.30e-14 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 74.04 E-value: 1.30e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIR--------WGTG--------- 390
Cdd:PRK13548 2 MLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRlngrpladWSPAelarrravl 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 391 ---------------VDLGYYDqHQSELHENKTVLDEVwdrfprMEQYEVRGALGLFLftgdevfepvSTLSGGEKGRV- 454
Cdd:PRK13548 82 pqhsslsfpftveevVAMGRAP-HGLSRAEDDALVAAA------LAQVDLAHLAGRDY----------PQLSGGEQQRVq 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 455 ---ALTELMLRKDN--VLLLDEPTNHLDMDSREALENALSDF----PGTIISVSHDryfIN---RFAEKVWVLDGNEI 520
Cdd:PRK13548 145 larVLAQLWEPDGPprWLLLDEPTSALDLAHQHHVLRLARQLaherGLAVIVVLHD---LNlaaRYADRIVLLHQGRL 219
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
14-220 |
1.41e-14 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 76.56 E-value: 1.41e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 14 GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM---------QKGLR--IGYLAQQGELTgEET 82
Cdd:TIGR02857 333 GRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVngvpladadADSWRdqIAWVPQHPFLF-AGT 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 VLETLEsvfepQRRMEAELRSLEQEMAESGSDpEALRILGGKYDTLTREfersNGYGwrssvqgvlaglelrefqdmktg 162
Cdd:TIGR02857 412 IAENIR-----LARPDASDAEIREALERAGLD-EFVAALPQGLDTPIGE----GGAG----------------------- 458
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 163 lLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG--AVLVISHDR 220
Cdd:TIGR02857 459 -LSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQgrTVLLVTHRL 517
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1-229 |
1.58e-14 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 73.92 E-value: 1.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMqKGLRIGYLA-------- 72
Cdd:COG0411 2 DPLLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILF-DGRDITGLPphriarlg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 73 -----QQGELTGEETVLETL---------ESVFEPQRRMEAELRSlEQEMAEsgsdpEALRILggkydtltrEFersngy 138
Cdd:COG0411 81 iartfQNPRLFPELTVLENVlvaaharlgRGLLAALLRLPRARRE-EREARE-----RAEELL---------ER------ 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 139 gwrssvqgvlagLELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPT---NHLDLKSIAWLEEYLAAFHG-AVL 214
Cdd:COG0411 140 ------------VGLADRADEPAGNLSYGQQRRLEIARALATEPKLLLLDEPAaglNPEETEELAELIRRLRDERGiTIL 207
|
250
....*....|....*
gi 1226689869 215 VISHDRYFLDRVCGR 229
Cdd:COG0411 208 LIEHDMDLVMGLADR 222
|
|
| LPS_export_lptB |
TIGR04406 |
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ... |
3-229 |
1.64e-14 |
|
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 275199 [Multi-domain] Cd Length: 239 Bit Score: 73.46 E-value: 1.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVS----------MQKGLR--IGY 70
Cdd:TIGR04406 1 TLVAENLIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILidgqdithlpMHERARlgIGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 71 LAQQGELTGEETVLETLESVFEPQRRMEAELRSLEQEmaesgsdpealrilggkydTLTREFErsngygwrssvqgvlag 150
Cdd:TIGR04406 81 LPQEASIFRKLTVEENIMAVLEIRKDLDRAEREERLE-------------------ALLEEFQ----------------- 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 151 leLREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD---LKSIAWLEEYLAAFHGAVLVISHD-RYFLDrV 226
Cdd:TIGR04406 125 --ISHLRDNKAMSLSGGERRRVEIARALATNPKFILLDEPFAGVDpiaVGDIKKIIKHLKERGIGVLITDHNvRETLD-I 201
|
...
gi 1226689869 227 CGR 229
Cdd:TIGR04406 202 CDR 204
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
334-516 |
1.67e-14 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 75.15 E-value: 1.67e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 334 LSKGYGDRILfrDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIR-----W---GTGVDL-------GYYDQ 398
Cdd:TIGR02142 5 FSKRLGDFSL--DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVlngrtLfdsRKGIFLppekrriGYVFQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 399 hQSELhenktvldevwdrFPrmeQYEVRGAL--GLFLFTGDE-----------------VFEPVSTLSGGEKGRVALTEL 459
Cdd:TIGR02142 83 -EARL-------------FP---HLSVRGNLryGMKRARPSErrisferviellgighlLGRLPGRLSGGEKQRVAIGRA 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 460 MLRKDNVLLLDEPTNHLDMDSREA----LENALSDFPGTIISVSHDRYFINRFAEKVWVLD 516
Cdd:TIGR02142 146 LLSSPRLLLMDEPLAALDDPRKYEilpyLERLHAEFGIPILYVSHSLQEVLRLADRVVVLE 206
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
298-501 |
2.20e-14 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 76.25 E-value: 2.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 298 RLDMVERLEKPEDESTirFRFETRRRTGDDVLMTEGLSKGY-GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIG 376
Cdd:TIGR02868 306 RIVEVLDAAGPVAEGS--APAAGAVGLGKPTLELRDLSAGYpGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAG 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 377 VEKPDAGVIRWgTGVDLGYYDQHQ----------------SELHEN-----KTVLD-EVWD--RFPRMEQYEVRGALGLf 432
Cdd:TIGR02868 384 LLDPLQGEVTL-DGVPVSSLDQDEvrrrvsvcaqdahlfdTTVRENlrlarPDATDeELWAalERVGLADWLRALPDGL- 461
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 433 lftGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREA-LENALSDFPG-TIISVSHD 501
Cdd:TIGR02868 462 ---DTVLGEGGARLSGGERQRLALARALLADAPILLLDEPTEHLDAETADElLEDLLAALSGrTVVLITHH 529
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
25-517 |
2.50e-14 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 75.98 E-value: 2.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 25 TLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmqkglrigylaqQGELTGEEtVLET-----LESVFepQRRMEA 99
Cdd:COG1245 95 VPKKGKVTGILGPNGIGKSTALKILSGELKPNLGDY-------------DEEPSWDE-VLKRfrgteLQDYF--KKLANG 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 100 ELR-SLEQEMAE------SGSDPEALRilggKYDTltrefersngygwRSSVQGVLAGLELREFQDMKTGLLSGGERTRL 172
Cdd:COG1245 159 EIKvAHKPQYVDlipkvfKGTVRELLE----KVDE-------------RGKLDELAEKLGLENILDRDISELSGGELQRV 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 173 CLGRMLLTEPDLLLLDEPTNHLDLK---SIAWLEEYLAAFHGAVLVISHDRYFLDrvcgrmaeLLLGNVE-TY--SGNY- 245
Cdd:COG1245 222 AIAAALLRDADFYFFDEPSSYLDIYqrlNVARLIRELAEEGKYVLVVEHDLAILD--------YLADYVHiLYgePGVYg 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 246 ------------TEYLEKrttvY---ENrMRAwklqqkeiaRQEAIiamyrRFNKEKSIRIANSKQKrldmverLEKPEd 310
Cdd:COG1245 294 vvskpksvrvgiNQYLDG----YlpeEN-VRI---------RDEPI-----EFEVHAPRREKEEETL-------VEYPD- 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 311 estirfrfetrrrtgddvlmtegLSKGYGDrilFRdLKMH---VRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRw 387
Cdd:COG1245 347 -----------------------LTKSYGG---FS-LEVEggeIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVD- 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 388 gTGVDLGYYDQH---------QSELHE-NKTVLDEVWdrfprmEQYEVRGALGLflftgDEVFE-PVSTLSGGEKGRVAL 456
Cdd:COG1245 399 -EDLKISYKPQYispdydgtvEEFLRSaNTDDFGSSY------YKTEIIKPLGL-----EKLLDkNVKDLSGGELQRVAI 466
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 457 TELMLRKDNVLLLDEPTNHLDMDSREALENALSDF----PGTIISVSHDRYFINRFAEKVWVLDG 517
Cdd:COG1245 467 AACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFaenrGKTAMVVDHDIYLIDYISDRLMVFEG 531
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
4-218 |
2.51e-14 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 72.01 E-value: 2.51e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM-------QKGLR---IGYLAQ 73
Cdd:TIGR01189 1 LAARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWngtplaeQRDEPhenILYLGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 74 QGELTGEETVLETLesvfepqrRMEAELRSLEQEMAEsgsdpEALRILGgkydtltrefersngygwrssvqgvlagleL 153
Cdd:TIGR01189 81 LPGLKPELSALENL--------HFWAAIHGGAQRTIE-----DALAAVG------------------------------L 117
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 154 REFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAfH----GAVLVISH 218
Cdd:TIGR01189 118 TGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVALLAGLLRA-HlargGIVLLTTH 185
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
327-477 |
2.66e-14 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 72.30 E-value: 2.66e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 327 DVLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEK--PDAGVIrwgtgvdlgyyDQHQSELH 404
Cdd:COG2401 29 IVLEAFGVELRVVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKgtPVAGCV-----------DVPDNQFG 97
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 405 ENKTVLDEVWDRFPRMEQYEVRGALGL---FLFtgdevFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLD 477
Cdd:COG2401 98 REASLIDAIGRKGDFKDAVELLNAVGLsdaVLW-----LRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLD 168
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
7-231 |
2.97e-14 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 72.40 E-value: 2.97e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 7 QDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGT--------VSMQKGLR--IGYLAQQ-- 74
Cdd:cd03265 4 ENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRatvaghdvVREPREVRrrIGIVFQDls 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 75 --GELTGEETVLetlesvfepqrrMEAelrsleqemaesgsdpealRILGGKYDTLTREFERsngygwrssvqgVLAGLE 152
Cdd:cd03265 84 vdDELTGWENLY------------IHA-------------------RLYGVPGAERRERIDE------------LLDFVG 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 153 LREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYL----AAFHGAVLVISHDRYFLDRVCG 228
Cdd:cd03265 121 LLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDPQTRAHVWEYIeklkEEFGMTILLTTHYMEEAEQLCD 200
|
...
gi 1226689869 229 RMA 231
Cdd:cd03265 201 RVA 203
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
344-522 |
5.92e-14 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 70.42 E-value: 5.92e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 344 FRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtgvdlgyyDQHQSELHENKTVLDEVWDRFPRMEQY 423
Cdd:cd03247 18 LKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLD--------GVPVSDLEKALSSLISVLNQRPYLFDT 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 424 EVRGALGLflftgdevfepvsTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLD-MDSREALENALSDFPG-TIISVSHD 501
Cdd:cd03247 90 TLRNNLGR-------------RFSGGERQRLALARILLQDAPIVLLDEPTVGLDpITERQLLSLIFEVLKDkTLIWITHH 156
|
170 180
....*....|....*....|.
gi 1226689869 502 RYFINRFaEKVWVLDGNEIKE 522
Cdd:cd03247 157 LTGIEHM-DKILFLENGKIIM 176
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-74 |
7.45e-14 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 71.68 E-value: 7.45e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQQ 74
Cdd:PRK09544 2 TSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKLRIGYVPQK 75
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
4-228 |
9.41e-14 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 71.45 E-value: 9.41e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGT-HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ---------KGLR-----I 68
Cdd:cd03256 1 IEVENLSKTYPNgKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDgtdinklkgKALRqlrrqI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 69 GYLAQQGELTGEETVLETlesvfepqrrmeaelrsleqemaesgsdpealrILGGKYDTLTreFERSnGYGW--RSSVQG 146
Cdd:cd03256 81 GMIFQQFNLIERLSVLEN---------------------------------VLSGRLGRRS--TWRS-LFGLfpKEEKQR 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 147 VLAGLE---LREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAF---HGAVLVIS-HD 219
Cdd:cd03256 125 ALAALErvgLLDKAYQRADQLSGGQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRInreEGITVIVSlHQ 204
|
250
....*....|...
gi 1226689869 220 ----RYFLDRVCG 228
Cdd:cd03256 205 vdlaREYADRIVG 217
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
4-257 |
1.30e-13 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 73.65 E-value: 1.30e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVkkSFG----THEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM---------QKGLR--I 68
Cdd:COG4987 334 LELEDV--SFRypgaGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLggvdlrdldEDDLRrrI 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 69 GYLAQQGEL--TgeeTVLETLesvfepqrRM------EAELRS-LEQemAESGsdpEALRILGGKYDTLTREfersngyg 139
Cdd:COG4987 412 AVVPQRPHLfdT---TLRENL--------RLarpdatDEELWAaLER--VGLG---DWLAALPDGLDTWLGE-------- 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 140 wrssvqgvlAGLelrefqdmktgLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSI-AWLEEYLAAFHG-AVLVIS 217
Cdd:COG4987 468 ---------GGR-----------RLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEqALLADLLEALAGrTVLLIT 527
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1226689869 218 HDRYFL---DRVC----GRMAElllgnvetySGNYTEYLEKRTTVYE 257
Cdd:COG4987 528 HRLAGLermDRILvledGRIVE---------QGTHEELLAQNGRYRQ 565
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
3-231 |
1.47e-13 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 71.37 E-value: 1.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTH---------EVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkglriGYLAQ 73
Cdd:TIGR02769 2 LLEVRDVTHTYRTGglfgakqraPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFR-----GQDLY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 74 QGELTGEETVLETLESVFE-------PQRRMEAELRsleqemaesgsdpEALRILggkydTLTREFERsngygwRSSVQG 146
Cdd:TIGR02769 77 QLDRKQRRAFRRDVQLVFQdspsavnPRMTVRQIIG-------------EPLRHL-----TSLDESEQ------KARIAE 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 147 VLAGLELR-EFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDL----KSIAWLEEYLAAFHGAVLVISHDRY 221
Cdd:TIGR02769 133 LLDMVGLRsEDADKLPRQLSGGQLQRINIARALAVKPKLIVLDEAVSNLDMvlqaVILELLRKLQQAFGTAYLFITHDLR 212
|
250
....*....|
gi 1226689869 222 FLDRVCGRMA 231
Cdd:TIGR02769 213 LVQSFCQRVA 222
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1-233 |
1.56e-13 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 72.17 E-value: 1.56e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM-------QKGL---RIGY 70
Cdd:PRK13536 39 TVAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVlgvpvpaRARLaraRIGV 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 71 LAQQGELTGEETVLETLeSVFEPQRRMEAelRSLEQEMaesgsdPEALrilggkydtltrEFERsngygwrssvqgvlag 150
Cdd:PRK13536 119 VPQFDNLDLEFTVRENL-LVFGRYFGMST--REIEAVI------PSLL------------EFAR---------------- 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 151 leLREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD--LKSIAWLE-EYLAAFHGAVLVISHDRYFLDRVC 227
Cdd:PRK13536 162 --LESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDphARHLIWERlRSLLARGKTILLTTHFMEEAERLC 239
|
....*.
gi 1226689869 228 GRMAEL 233
Cdd:PRK13536 240 DRLCVL 245
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
332-516 |
1.73e-13 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 70.16 E-value: 1.73e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGY-----GDRIL--FRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW---GTGVDL-------- 393
Cdd:COG4778 8 ENLSKTFtlhlqGGKRLpvLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVrhdGGWVDLaqasprei 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 394 --------GYYDQHqselhenktvLDEVwdrfPRMEQYEV-------RG-------ALGLFLFTGDEVFE-----PVSTL 446
Cdd:COG4778 88 lalrrrtiGYVSQF----------LRVI----PRVSALDVvaeplleRGvdreearARARELLARLNLPErlwdlPPATF 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 447 SGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREA----LENALSDfpGT-IISVSHDRYFINRFAEKVWVLD 516
Cdd:COG4778 154 SGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVvvelIEEAKAR--GTaIIGIFHDEEVREAVADRVVDVT 226
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
345-520 |
2.16e-13 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 70.05 E-value: 2.16e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 345 RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtgvDLGYYDQHQSELHENKTVL---DEVWDRFPRME 421
Cdd:cd03267 38 KGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVA---GLVPWKRRKKFLRRIGVVFgqkTQLWWDLPVID 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 422 QYEV---------------RGALGLFLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALEN 486
Cdd:cd03267 115 SFYLlaaiydlpparfkkrLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRN 194
|
170 180 190
....*....|....*....|....*....|....*...
gi 1226689869 487 ALSDF----PGTIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:cd03267 195 FLKEYnrerGTTVLLTSHYMKDIEALARRVLVIDKGRL 232
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
332-522 |
2.24e-13 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 71.37 E-value: 2.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW-GTGVD---------LGYYDQHQS 401
Cdd:PRK13537 11 RNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLcGEPVPsrarharqrVGVVPQFDN 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 402 eLHENKTVLDE--VWDRFPRMEQYEVRGAL-GLFLFTGDE--VFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHL 476
Cdd:PRK13537 91 -LDPDFTVRENllVFGRYFGLSAAAARALVpPLLEFAKLEnkADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGL 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 477 DMDSR----EALENALSDfPGTIISVSHDRYFINRFAEKVWVLD-GNEIKE 522
Cdd:PRK13537 170 DPQARhlmwERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVIEeGRKIAE 219
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
346-522 |
2.36e-13 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 70.81 E-value: 2.36e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 346 DLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIR-----------WGTGVDLGYYDQHQSELHENKTVLDEVw 414
Cdd:PRK13635 25 DVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITvggmvlseetvWDVRRQVGMVFQNPDNQFVGATVQDDV- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 415 dRF-------PRMEQYE-VRGALGLFLFTGDEVFEPvSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSR-EALE 485
Cdd:PRK13635 104 -AFglenigvPREEMVErVDQALRQVGMEDFLNREP-HRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRrEVLE 181
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1226689869 486 NA--LSDFPG-TIISVSHDryfINR--FAEKVWVLDGNEIKE 522
Cdd:PRK13635 182 TVrqLKEQKGiTVLSITHD---LDEaaQADRVIVMNKGEILE 220
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-238 |
2.44e-13 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 72.18 E-value: 2.44e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-----------SMQKGLRIG 69
Cdd:PRK09536 1 MPMIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVlvagddvealsARAASRRVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 70 YLAQQGELTGEETVLETLESVFEPQRrmeaelrsleqemaesgsdpealrilgGKYDTLTREFERsngygwrsSVQGVLA 149
Cdd:PRK09536 81 SVPQDTSLSFEFDVRQVVEMGRTPHR---------------------------SRFDTWTETDRA--------AVERAME 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 150 GLELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDL-KSIAWLE--EYLAAFHGAVLVISHDRYFLDRV 226
Cdd:PRK09536 126 RTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLDInHQVRTLElvRRLVDDGKTAVAAIHDLDLAARY 205
|
250
....*....|..
gi 1226689869 227 CGRMAELLLGNV 238
Cdd:PRK09536 206 CDELVLLADGRV 217
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
3-238 |
2.63e-13 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 69.32 E-value: 2.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSF----GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmqkglrigylaqqgELT 78
Cdd:cd03266 1 MITADALTKRFrdvkKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFA---------------TVD 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 79 GeetvLETLESVFEPQRRMEaeLRSLEQEMAESGSDPEALRILGGKYDTLTREFErsngygwrSSVQGVLAGLELREFQD 158
Cdd:cd03266 66 G----FDVVKEPAEARRRLG--FVSDSTGLYDRLTARENLEYFAGLYGLKGDELT--------ARLEELADRLGMEELLD 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 159 MKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG---AVLVISHDRYFLDRVCGRMAELLL 235
Cdd:cd03266 132 RRVGGFSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRAlgkCILFSTHIMQEVERLCDRVVVLHR 211
|
...
gi 1226689869 236 GNV 238
Cdd:cd03266 212 GRV 214
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
4-195 |
2.65e-13 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 69.14 E-value: 2.65e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGerM-GLVGVNGSGKSTIMKIIAGLETADSGTV--------SMQKGLR--IGYLA 72
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVSLTLGPG--MyGLLGPNGAGKTTLMRILATLTPPSSGTIridgqdvlKQPQKLRrrIGYLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 73 QQgeltgeetvletlesvFEPQRRMEAElrsleqemaesgsdpEALRILGGKYDTLTREFersngygwRSSVQGVLAGLE 152
Cdd:cd03264 79 QE----------------FGVYPNFTVR---------------EFLDYIAWLKGIPSKEV--------KARVDEVLELVN 119
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1226689869 153 LREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD 195
Cdd:cd03264 120 LGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLD 162
|
|
| F420-0_ABC_ATP |
TIGR03873 |
proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ... |
4-227 |
2.68e-13 |
|
proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ATP-binding protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and a permease (TIGR03869). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with a F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this ATP-binding protein is a component of an F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.
Pssm-ID: 163585 [Multi-domain] Cd Length: 256 Bit Score: 70.23 E-value: 2.68e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM-----------QKGLRIGYLA 72
Cdd:TIGR03873 2 LRLSRVSWSAGGRLIVDGVDVTAPPGSLTGLLGPNGSGKSTLLRLLAGALRPDAGTVDLagvdlhglsrrARARRVALVE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 73 QQGELTGEETVLETLESVFEPQRRMEAelrsleqemAESGSDPEAlrilggkydtltrefersngygwrssVQGVLAGLE 152
Cdd:TIGR03873 82 QDSDTAVPLTVRDVVALGRIPHRSLWA---------GDSPHDAAV--------------------------VDRALARTE 126
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 153 LREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD----LKSIAWLEEyLAAFHGAVLVISHDRYFLDRVC 227
Cdd:TIGR03873 127 LSHLADRDMSTLSGGERQRVHVARALAQEPKLLLLDEPTNHLDvraqLETLALVRE-LAATGVTVVAALHDLNLAASYC 204
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
329-523 |
2.93e-13 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 69.73 E-value: 2.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW----------GTGVDlgyydq 398
Cdd:COG1134 27 LLLRRRRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVngrvsallelGAGFH------ 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 399 hqSEL--HEN---------------KTVLDEVWDrfprmeqyevrgalglflFTGDEVF--EPVSTLSGGEKGRVAL-TE 458
Cdd:COG1134 101 --PELtgRENiylngrllglsrkeiDEKFDEIVE------------------FAELGDFidQPVKTYSSGMRARLAFaVA 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 459 LMLRKDnVLLLDEPTNHLDMDSREALENALSDF---PGTIISVSHDRYFINRFAEKVWVLDGNEIKEY 523
Cdd:COG1134 161 TAVDPD-ILLVDEVLAVGDAAFQKKCLARIRELresGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMD 227
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
329-515 |
3.19e-13 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 68.85 E-value: 3.19e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW-GTGVD------LGYYDQHQS 401
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFdGKPLDiaarnrIGYLPEERG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 402 eLHENKTVLDeVWDRFPRMEQYEVRGA----------LGLflftGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDE 471
Cdd:cd03269 81 -LYPKMKVID-QLVYLAQLKGLKKEEArrridewlerLEL----SEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDE 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1226689869 472 PTNHLDMDSREALENALSDFPG---TIISVSHDRYFINRFAEKVWVL 515
Cdd:cd03269 155 PFSGLDPVNVELLKDVIRELARagkTVILSTHQMELVEELCDRVLLL 201
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
332-523 |
3.88e-13 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 68.59 E-value: 3.88e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRI--LFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYDQHqsELHENKTV 409
Cdd:cd03369 10 ENLSVRYAPDLppVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEI-DGIDISTIPLE--DLRSSLTI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 410 L--DEVW---------DRFPRMEQYEVRGALglflftgdEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDM 478
Cdd:cd03369 87 IpqDPTLfsgtirsnlDPFDEYSDEEIYGAL--------RVSEGGLNLSQGQRQLLCLARALLKRPRVLVLDEATASIDY 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1226689869 479 DSREALENAL-SDFPG-TIISVSHDRYFINRFAeKVWVLDGNEIKEY 523
Cdd:cd03369 159 ATDALIQKTIrEEFTNsTILTIAHRLRTIIDYD-KILVMDAGEVKEY 204
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
4-197 |
4.11e-13 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 68.82 E-value: 4.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmqkglrigylaqqgeLTGEETV 83
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRI----------------YIGGRDV 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 84 LETlesvfEPQRR---MEAELRSLEQEMaeSGSDPEA--LRILGGKYDTLTREfersngygwrssVQGVLAGLELREFQD 158
Cdd:cd03301 65 TDL-----PPKDRdiaMVFQNYALYPHM--TVYDNIAfgLKLRKVPKDEIDER------------VREVAELLQIEHLLD 125
|
170 180 190
....*....|....*....|....*....|....*....
gi 1226689869 159 MKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLK 197
Cdd:cd03301 126 RKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAK 164
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
7-239 |
4.44e-13 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 69.29 E-value: 4.44e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 7 QDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM------QKGLR---IGYLAQQGEL 77
Cdd:cd03296 6 RNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFggedatDVPVQernVGFVFQHYAL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 78 TGEETVLETLESVFEPQRRMEaelRSLEQEMaesgsdpealrilggkydtltrefersngygwRSSVQGVLAGLELREFQ 157
Cdd:cd03296 86 FRHMTVFDNVAFGLRVKPRSE---RPPEAEI--------------------------------RAKVHELLKLVQLDWLA 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 158 DMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKS----IAWLEEYLAAFHGAVLVISHDRYFLDRVCGRMAEL 233
Cdd:cd03296 131 DRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDAKVrkelRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVM 210
|
....*.
gi 1226689869 234 LLGNVE 239
Cdd:cd03296 211 NKGRIE 216
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
326-522 |
5.29e-13 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 71.86 E-value: 5.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 326 DDVLMTEGLSKGY--GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDA---GVIRWGtGVDL------- 393
Cdd:COG1123 2 TPLLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGrisGEVLLD-GRDLlelseal 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 394 -----GYYDQHQSELHENKTVLDEVWD--RFPRMEQYEVRG-ALGLFLFTGDEVFE--PVSTLSGGEKGRVALTELMLRK 463
Cdd:COG1123 81 rgrriGMVFQDPMTQLNPVTVGDQIAEalENLGLSRAEARArVLELLEAVGLERRLdrYPHQLSGGQRQRVAIAMALALD 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 464 DNVLLLDEPTNHLDMDSR----EALENALSDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKE 522
Cdd:COG1123 161 PDLLIADEPTTALDVTTQaeilDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVE 223
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
3-230 |
6.05e-13 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 69.83 E-value: 6.05e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM----------QKGLRIGYLA 72
Cdd:PRK13537 7 PIDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLcgepvpsrarHARQRVGVVP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 73 QQGELTGEETVLETlesvfepqrrmeaelrsleqemaesgsdpeaLRILGgkydtltREFERSNGYGwRSSVQGVLAGLE 152
Cdd:PRK13537 87 QFDNLDPDFTVREN-------------------------------LLVFG-------RYFGLSAAAA-RALVPPLLEFAK 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 153 LREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD--LKSIAW--LEEYLAAfHGAVLVISHDRYFLDRVCG 228
Cdd:PRK13537 128 LENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDpqARHLMWerLRSLLAR-GKTILLTTHFMEEAERLCD 206
|
..
gi 1226689869 229 RM 230
Cdd:PRK13537 207 RL 208
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
332-515 |
6.45e-13 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 68.36 E-value: 6.45e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGY-GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIrWGTGVDLG---------------- 394
Cdd:PRK10908 5 EHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKI-WFSGHDITrlknrevpflrrqigm 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 395 -YYDQHqseLHENKTVLDEVwdRFPRMeqyeVRGAlglflfTGDEVFEPVST-----------------LSGGEKGRVAL 456
Cdd:PRK10908 84 iFQDHH---LLMDRTVYDNV--AIPLI----IAGA------SGDDIRRRVSAaldkvglldkaknfpiqLSGGEQQRVGI 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 457 TELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPG---TIISVSHDRYFINRFAEKVWVL 515
Cdd:PRK10908 149 ARAVVNKPAVLLADEPTGNLDDALSEGILRLFEEFNRvgvTVLMATHDIGLISRRSYRMLTL 210
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1-190 |
6.49e-13 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 68.90 E-value: 6.49e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM--------------QKGl 66
Cdd:COG1137 1 MMTLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLdgedithlpmhkraRLG- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 67 rIGYLAQQ----GELTGEETVLETLESVFEPQRRMEAELRSLeqemaesgsdpealrilggkydtltrefersngygwrs 142
Cdd:COG1137 80 -IGYLPQEasifRKLTVEDNILAVLELRKLSKKEREERLEEL-------------------------------------- 120
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 143 svqgvlagleLREFQ-----DMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEP 190
Cdd:COG1137 121 ----------LEEFGithlrKSKAYSLSGGERRRVEIARALATNPKFILLDEP 163
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1-233 |
7.74e-13 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 68.16 E-value: 7.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIilALQDVKKSFGT-HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVS--------MQKG----LR 67
Cdd:COG2884 1 MI--RFENVSKRYPGgREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLvngqdlsrLKRReipyLR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 68 --IGYLAQQGELTGEETVLETLEsvFepqrrmeaelrsleqemaesgsdpeALRILGGKYDTLTREfersngygwrssVQ 145
Cdd:COG2884 79 rrIGVVFQDFRLLPDRTVYENVA--L-------------------------PLRVTGKSRKEIRRR------------VR 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 146 GVLAGLELREFQDMKTGLLSGGERTRLCLGRmlltepdllllDEPTNHLDLKSIAWLEEYLAAFH--G-AVLVISHDRYF 222
Cdd:COG2884 120 EVLDLVGLSDKAKALPHELSGGEQQRVAIARalvnrpelllaDEPTGNLDPETSWEIMELLEEINrrGtTVLIATHDLEL 199
|
250
....*....|.
gi 1226689869 223 LDRVCGRMAEL 233
Cdd:COG2884 200 VDRMPKRVLEL 210
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
332-522 |
8.26e-13 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 68.62 E-value: 8.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWG-----TGVDLGYYD-------QH 399
Cdd:PRK11264 7 KNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGditidTARSLSQQKglirqlrQH 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 400 -----QS-ELHENKTVLDEVWD------RFPRmEQYEVRG-----ALGLflfTGDEVFEPvSTLSGGEKGRVALTELMLR 462
Cdd:PRK11264 87 vgfvfQNfNLFPHRTVLENIIEgpvivkGEPK-EEATARArellaKVGL---AGKETSYP-RRLSGGQQQRVAIARALAM 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 463 KDNVLLLDEPTNHLDMD-SREALEN--ALSDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKE 522
Cdd:PRK11264 162 RPEVILFDEPTSALDPElVGEVLNTirQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVE 224
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
17-218 |
8.84e-13 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 67.59 E-value: 8.84e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 17 EVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKG--------LRIGYLAQQGELTGEETVLETLE 88
Cdd:PRK13539 16 VLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGdiddpdvaEACHYLGHRNAMKPALTVAENLE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 89 svFEPqrrmeaelrsleqemaesgsdpealRILGGKydtltrefersngygwRSSVQGVLAGLELREFQDMKTGLLSGGE 168
Cdd:PRK13539 96 --FWA-------------------------AFLGGE----------------ELDIAAALEAVGLAPLAHLPFGYLSAGQ 132
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 169 RTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAfH----GAVLVISH 218
Cdd:PRK13539 133 KRRVALARLLVSNRPIWILDEPTAALDAAAVALFAELIRA-HlaqgGIVIAATH 185
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
332-522 |
9.12e-13 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 70.11 E-value: 9.12e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW-GTGVD--------LGYYDQHQSe 402
Cdd:PRK10851 6 ANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFhGTDVSrlhardrkVGFVFQHYA- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 403 LHENKTVLDE------VWDRFPRMEQYEVRGALGLFLftgdevfEPV----------STLSGGEKGRVALTELMLRKDNV 466
Cdd:PRK10851 85 LFRHMTVFDNiafgltVLPRRERPNAAAIKAKVTQLL-------EMVqlahladrypAQLSGGQKQRVALARALAVEPQI 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 467 LLLDEPTNHLDMDSREALENAL----SDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKE 522
Cdd:PRK10851 158 LLLDEPFGALDAQVRKELRRWLrqlhEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQ 217
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
4-219 |
1.02e-12 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 70.85 E-value: 1.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSF-GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM-----------QKGLRIGYL 71
Cdd:TIGR02868 335 LELRDLSAGYpGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLdgvpvssldqdEVRRRVSVC 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 72 AQQGELTGEeTVLETLesvfepqrRMEAElrsleqemaeSGSDPEALRILggkydtltrefERsngygwrssvqgvlAGL 151
Cdd:TIGR02868 415 AQDAHLFDT-TVRENL--------RLARP----------DATDEELWAAL-----------ER--------------VGL 450
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 152 E--LREFQD-----MKTG--LLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLK-SIAWLEEYLAAFHG-AVLVISHD 219
Cdd:TIGR02868 451 AdwLRALPDgldtvLGEGgaRLSGGERQRLALARALLADAPILLLDEPTEHLDAEtADELLEDLLAALSGrTVVLITHH 529
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
18-218 |
1.34e-12 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 67.13 E-value: 1.34e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 18 VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGL----------RIGYLAQQGELTGEETVLETL 87
Cdd:cd03231 15 LFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPldfqrdsiarGLLYLGHAPGIKTTLSVLENL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 88 esvfepqrrmeaelrsleqemaesgsdpealrilggkydtltREFERSNGygwRSSVQGVLAGLELREFQDMKTGLLSGG 167
Cdd:cd03231 95 ------------------------------------------RFWHADHS---DEQVEEALARVGLNGFEDRPVAQLSAG 129
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 168 ERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAfH----GAVLVISH 218
Cdd:cd03231 130 QQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAG-HcargGMVVLTTH 183
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
333-520 |
1.60e-12 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 69.49 E-value: 1.60e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 333 GLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYD------QHQSELHEN 406
Cdd:PRK09536 8 DLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVA-GDDVEALSaraasrRVASVPQDT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 407 KTVLDEVWDRFPRMEQYEVRGALGLFLFTGDEVFE--------------PVSTLSGGEKGRVALTELMLRKDNVLLLDEP 472
Cdd:PRK09536 87 SLSFEFDVRQVVEMGRTPHRSRFDTWTETDRAAVEramertgvaqfadrPVTSLSGGERQRVLLARALAQATPVLLLDEP 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 473 TNHLDMDSR-EALENA--LSDFPGTIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:PRK09536 167 TASLDINHQvRTLELVrrLVDDGKTAVAAIHDLDLAARYCDELVLLADGRV 217
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
345-522 |
1.68e-12 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 67.26 E-value: 1.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 345 RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYDQH----------QSELHENKTVLDEVW 414
Cdd:cd03251 19 RDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILI-DGHDVRDYTLAslrrqiglvsQDVFLFNDTVAENIA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 415 DRFPRMEQYEVRGALGL-----FLFTGDEVFEPV-----STLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDS---- 480
Cdd:cd03251 98 YGRPGATREEVEEAARAanaheFIMELPEGYDTVigergVKLSGGQRQRIAIARALLKDPPILILDEATSALDTESerlv 177
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1226689869 481 REALENALSDfpGTIISVSHdRYFINRFAEKVWVLDGNEIKE 522
Cdd:cd03251 178 QAALERLMKN--RTTFVIAH-RLSTIENADRIVVLEDGKIVE 216
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
340-522 |
1.85e-12 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 70.52 E-value: 1.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 340 DRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYDQH----------QSELHENKTV 409
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLL-DGVPLVQYDHHylhrqvalvgQEPVLFSGSV 571
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 410 LDEVWDRFPRMEQYEVRGA---------LGLFLFTGD-EVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMD 479
Cdd:TIGR00958 572 RENIAYGLTDTPDEEIMAAakaanahdfIMEFPNGYDtEVGEKGSQLSGGQKQRIAIARALVRKPRVLILDEATSALDAE 651
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1226689869 480 SREALENALSDFPGTIISVSHdRYFINRFAEKVWVLDGNEIKE 522
Cdd:TIGR00958 652 CEQLLQESRSRASRTVLLIAH-RLSTVERADQILVLKKGSVVE 693
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
340-520 |
1.91e-12 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 67.11 E-value: 1.91e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 340 DRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYDQHQseLHE------------NK 407
Cdd:cd03248 26 DTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLL-DGKPISQYEHKY--LHSkvslvgqepvlfAR 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 408 TVLDEVWDRFPRMEQYEVRGA----------LGLFLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLD 477
Cdd:cd03248 103 SLQDNIAYGLQSCSFECVKEAaqkahahsfiSELASGYDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSALD 182
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1226689869 478 MDSREALENALSDFPG--TIISVSHDRYFINRfAEKVWVLDGNEI 520
Cdd:cd03248 183 AESEQQVQQALYDWPErrTVLVIAHRLSTVER-ADQILVLDGGRI 226
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
6-60 |
1.92e-12 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 66.78 E-value: 1.92e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 6 LQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:cd03262 3 IKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTI 57
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-61 |
1.93e-12 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 69.10 E-value: 1.93e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 1 MIILALQDVKKSF-GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVS 61
Cdd:PRK11650 1 MAGLKLQAVRKSYdGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIW 62
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
331-522 |
2.68e-12 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 67.40 E-value: 2.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 331 TEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYDQHQ---------- 400
Cdd:PRK10419 15 HGGLSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSW-RGEPLAKLNRAQrkafrrdiqm 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 ------SELHENKTV-------------LDEVwDRFPRMEqyEVRGALGLFLFTGDEVfePVStLSGGEKGRVALTELML 461
Cdd:PRK10419 94 vfqdsiSAVNPRKTVreiireplrhllsLDKA-ERLARAS--EMLRAVDLDDSVLDKR--PPQ-LSGGQLQRVCLARALA 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 462 RKDNVLLLDEPTNHLDM---DSREALENALSDFPGT-IISVSHDRYFINRFAEKVWVLDGNEIKE 522
Cdd:PRK10419 168 VEPKLLILDEAVSNLDLvlqAGVIRLLKKLQQQFGTaCLFITHDLRLVERFCQRVMVMDNGQIVE 232
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
4-219 |
3.12e-12 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 69.40 E-value: 3.12e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVkkSF---GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-------------SMQKglR 67
Cdd:COG4988 337 IELEDV--SFsypGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSIlingvdlsdldpaSWRR--Q 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 68 IGYLAQQGEL-TGeeTVLETLesvfepqrRM---EAELRSLEQEMAESGSDpEALRILGGKYDTLTREfersNGYGwrss 143
Cdd:COG4988 413 IAWVPQNPYLfAG--TIRENL--------RLgrpDASDEELEAALEAAGLD-EFVAALPDGLDTPLGE----GGRG---- 473
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 144 vqgvlaglelrefqdmktglLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYL-AAFHG-AVLVISHD 219
Cdd:COG4988 474 --------------------LSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALrRLAKGrTVILITHR 531
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
332-501 |
3.30e-12 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 68.18 E-value: 3.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDlgyydqhqselhenktVLD 411
Cdd:COG3839 7 ENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIG-GRD----------------VTD 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 412 -EVWDR-----------FPRMEQYE-------VRGA---------------LGLflftgdevfEP-----VSTLSGGEKG 452
Cdd:COG3839 70 lPPKDRniamvfqsyalYPHMTVYEniafplkLRKVpkaeidrrvreaaelLGL---------EDlldrkPKQLSGGQRQ 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 453 RVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSD----FPGTIISVSHD 501
Cdd:COG3839 141 RVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRlhrrLGTTTIYVTHD 193
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
16-226 |
3.37e-12 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 66.07 E-value: 3.37e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 16 HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkGL------------RIGYLAQQGEL-TGeeT 82
Cdd:cd03245 17 IPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLD-GTdirqldpadlrrNIGYVPQDVTLfYG--T 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 VLETLESvfepqRRMEAELRSLEQEMAESGSDPEALRILGGkYDTLTREfersNGYGwrssvqgvlaglelrefqdmktg 162
Cdd:cd03245 94 LRDNITL-----GAPLADDERILRAAELAGVTDFVNKHPNG-LDLQIGE----RGRG----------------------- 140
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 163 lLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAF--HGAVLVISHDRYFLDRV 226
Cdd:cd03245 141 -LSGGQRQAVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLlgDKTLIIITHRPSLLDLV 205
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
17-233 |
3.46e-12 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 66.38 E-value: 3.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 17 EVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV---------------SMQKGLRIGYLAQQGELTGEE 81
Cdd:PRK11629 23 DVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVifngqpmsklssaakAELRNQKLGFIYQFHHLLPDF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 82 TvleTLESVFEP-----QRRMEAELRSLEQEMAesgsdpealrilggkydtltrefersngygwrssvqgvlAGLELREF 156
Cdd:PRK11629 103 T---ALENVAMPlligkKKPAEINSRALEMLAA---------------------------------------VGLEHRAN 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 157 QdmKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLK---SIAWLEEYLAAFHG-AVLVISHDRYFLDRVcGRMAE 232
Cdd:PRK11629 141 H--RPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARnadSIFQLLGELNRLQGtAFLVVTHDLQLAKRM-SRQLE 217
|
.
gi 1226689869 233 L 233
Cdd:PRK11629 218 M 218
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
339-522 |
3.67e-12 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 66.48 E-value: 3.67e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 339 GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQseLHEN-KTVLDEVW--- 414
Cdd:cd03254 14 EKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILID-GIDIRDISRKS--LRSMiGVVLQDTFlfs 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 415 -----------DRFPRMEQYEVRGALGLFLFTGD-------EVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHL 476
Cdd:cd03254 91 gtimenirlgrPNATDEEVIEAAKEAGAHDFIMKlpngydtVLGENGGNLSQGERQLLAIARAMLRDPKILILDEATSNI 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1226689869 477 DMDSREALENALSD-FPG-TIISVSHdRYFINRFAEKVWVLDGNEIKE 522
Cdd:cd03254 171 DTETEKLIQEALEKlMKGrTSIIIAH-RLSTIKNADKILVLDDGKIIE 217
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
345-522 |
4.06e-12 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 67.02 E-value: 4.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 345 RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAG-VIRWGTGVDlgyYDQhQSELHENKTV-------LDEVWDr 416
Cdd:PRK13639 19 KGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGeVLIKGEPIK---YDK-KSLLEVRKTVgivfqnpDDQLFA- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 417 fPRMEQYEVRGALGLFLfTGDEV---------------FE--PVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMD 479
Cdd:PRK13639 94 -PTVEEDVAFGPLNLGL-SKEEVekrvkealkavgmegFEnkPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPM 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1226689869 480 SREALENALSDFPG---TIISVSHDRYFINRFAEKVWVL-DGNEIKE 522
Cdd:PRK13639 172 GASQIMKLLYDLNKegiTIIISTHDVDLVPVYADKVYVMsDGKIIKE 218
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
346-520 |
5.32e-12 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 66.99 E-value: 5.32e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 346 DLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIR------WGTGVDLGY----------YDQHQ--------- 400
Cdd:PRK13637 25 NVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIidgvdiTDKKVKLSDirkkvglvfqYPEYQlfeetiekd 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 -----SELHENKtvlDEVWDRFPR-ME----QYEVrgalglflFTGDEVFEpvstLSGGEKGRVALTELMLRKDNVLLLD 470
Cdd:PRK13637 105 iafgpINLGLSE---EEIENRVKRaMNivglDYED--------YKDKSPFE----LSGGQKRRVAIAGVVAMEPKILILD 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 471 EPTNHLDMDSREALENALSD----FPGTIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:PRK13637 170 EPTAGLDPKGRDEILNKIKElhkeYNMTIILVSHSMEDVAKLADRIIVMNKGKC 223
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
340-522 |
5.64e-12 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 68.59 E-value: 5.64e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 340 DRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYD-----QHQSELHE-----NKTV 409
Cdd:TIGR02203 344 DRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILL-DGHDLADYTlaslrRQVALVSQdvvlfNDTI 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 410 LDEVwdRFPRMEQY---EVRGAL----------GLFLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHL 476
Cdd:TIGR02203 423 ANNI--AYGRTEQAdraEIERALaaayaqdfvdKLPLGLDTPIGENGVLLSGGQRQRLAIARALLKDAPILILDEATSAL 500
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1226689869 477 DMDSREALENALSDF-PG-TIISVSHDRYFINRfAEKVWVLDGNEIKE 522
Cdd:TIGR02203 501 DNESERLVQAALERLmQGrTTLVIAHRLSTIEK-ADRIVVMDDGRIVE 547
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
3-85 |
5.86e-12 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 65.68 E-value: 5.86e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTH----EVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ---------KGLR-- 67
Cdd:cd03258 1 MIELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDgtdltllsgKELRka 80
|
90 100
....*....|....*....|.
gi 1226689869 68 ---IGYLAQQGELTGEETVLE 85
Cdd:cd03258 81 rrrIGMIFQHFNLLSSRTVFE 101
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
332-529 |
6.57e-12 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 68.31 E-value: 6.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRIL--FRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQhqSELHENKTV 409
Cdd:PRK11160 342 NNVSFTYPDQPQpvLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLN-GQPIADYSE--AALRQAISV 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 410 LDEVWDRF------------PRMEQYEVRGAL---GL-FLFTGDEvfePVST--------LSGGEKGRVALTELMLRKDN 465
Cdd:PRK11160 419 VSQRVHLFsatlrdnlllaaPNASDEALIEVLqqvGLeKLLEDDK---GLNAwlgeggrqLSGGEQRRLGIARALLHDAP 495
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 466 VLLLDEPTNHLDMDS-REALENALSDFPG-TIISVSHDRYFINRFaEKVWVLDGNEIKEYlGNYDS 529
Cdd:PRK11160 496 LLLLDEPTEGLDAETeRQILELLAEHAQNkTVLMITHRLTGLEQF-DRICVMDNGQIIEQ-GTHQE 559
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
330-522 |
6.63e-12 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 65.88 E-value: 6.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 330 MTE--GLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAG-VIRWGTGVDLGYYDQHQSELhEN 406
Cdd:PRK09493 1 MIEfkNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGdLIVDGLKVNDPKVDERLIRQ-EA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 407 KTVLDEvWDRFPRMEQYE--------VRGA-------LGLFLFTGDEVFEPV----STLSGGEKGRVALTELMLRKDNVL 467
Cdd:PRK09493 80 GMVFQQ-FYLFPHLTALEnvmfgplrVRGAskeeaekQARELLAKVGLAERAhhypSELSGGQQQRVAIARALAVKPKLM 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 468 LLDEPTNHLDMDSR-EALE--NALSDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKE 522
Cdd:PRK09493 159 LFDEPTSALDPELRhEVLKvmQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAE 216
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
336-523 |
6.91e-12 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 65.25 E-value: 6.91e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 336 KGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVI------RWGTGVDLGYydqhQSEL--HEN- 406
Cdd:cd03220 30 GEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVtvrgrvSSLLGLGGGF----NPELtgRENi 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 407 --------------KTVLDEVWDrfprmeqyevrgalglflFT--GDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLD 470
Cdd:cd03220 106 ylngrllglsrkeiDEKIDEIIE------------------FSelGDFIDLPVKTYSSGMKARLAFAIATALEPDILLID 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 471 EPT----NHLDMDSREALENALSDfPGTIISVSHDRYFINRFAEKVWVLDGNEIKEY 523
Cdd:cd03220 168 EVLavgdAAFQEKCQRRLRELLKQ-GKTVILVSHDPSSIKRLCDRALVLEKGKIRFD 223
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
340-522 |
7.28e-12 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 65.64 E-value: 7.28e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 340 DRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVI------------RW----------------GT-- 389
Cdd:cd03249 15 DVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEIlldgvdirdlnlRWlrsqiglvsqepvlfdGTia 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 390 -GVDLGYYDQHQSELHE--NKTVLDEVWDRFPrmEQYEVR-GALGlflftgdevfepvSTLSGGEKGRVALTELMLRKDN 465
Cdd:cd03249 95 eNIRYGKPDATDEEVEEaaKKANIHDFIMSLP--DGYDTLvGERG-------------SQLSGGQKQRIAIARALLRNPK 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 466 VLLLDEPTNHLDMDS----REALENALSDFpgTIISVSHdRYFINRFAEKVWVLDGNEIKE 522
Cdd:cd03249 160 ILLLDEATSALDAESeklvQEALDRAMKGR--TTIVIAH-RLSTIRNADLIAVLQNGQVVE 217
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
331-521 |
7.29e-12 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 66.30 E-value: 7.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 331 TEGLSKGY--GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRwgtgVDlGYYDQHQSELHE--- 405
Cdd:TIGR04520 3 VENVSFSYpeSEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVT----VD-GLDTLDEENLWEirk 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 ----------NK----TVLDEVwdRF-------PRMEQYE-VRGALGLFLFTGDEVFEPvSTLSGGEKGRVALTELM-LR 462
Cdd:TIGR04520 78 kvgmvfqnpdNQfvgaTVEDDV--AFglenlgvPREEMRKrVDEALKLVGMEDFRDREP-HLLSGGQKQRVAIAGVLaMR 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 463 KDnVLLLDEPTNHLDMDSR-EALENALS---DFPGTIISVSHDryfIN--RFAEKVWVLDGNEIK 521
Cdd:TIGR04520 155 PD-IIILDEATSMLDPKGRkEVLETIRKlnkEEGITVISITHD---MEeaVLADRVIVMNKGKIV 215
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
337-522 |
8.01e-12 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 65.33 E-value: 8.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 337 GYGD-RILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQH----------QSELHE 405
Cdd:cd03253 9 AYDPgRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILID-GQDIREVTLDslrraigvvpQDTVLF 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 NKTVLDEVwdRFPRM-----EQYEVRGALGL------FLFTGD-EVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPT 473
Cdd:cd03253 88 NDTIGYNI--RYGRPdatdeEVIEAAKAAQIhdkimrFPDGYDtIVGERGLKLSGGEKQRVAIARAILKNPPILLLDEAT 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 474 NHLDMDSREALENALSDFPG--TIISVSHD-RYFINrfAEKVWVLDGNEIKE 522
Cdd:cd03253 166 SALDTHTEREIQAALRDVSKgrTTIVIAHRlSTIVN--ADKIIVLKDGRIVE 215
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
340-520 |
1.03e-11 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 65.58 E-value: 1.03e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 340 DRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVI--------RWGTGV---DLGYYDQhQSELHENKT 408
Cdd:PRK10575 23 GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEIlldaqpleSWSSKAfarKVAYLPQ-QLPAAEGMT 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 409 VLDEVwdrfpRMEQYEVRGALGLFLFTGDEVFEP--------------VSTLSGGEKGRVALTELMLRKDNVLLLDEPTN 474
Cdd:PRK10575 102 VRELV-----AIGRYPWHGALGRFGAADREKVEEaislvglkplahrlVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTS 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1226689869 475 HLDMDSRE---ALENALSDFPG-TIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:PRK10575 177 ALDIAHQVdvlALVHRLSQERGlTVIAVLHDINMAARYCDYLVALRGGEM 226
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1-218 |
1.03e-11 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 65.49 E-value: 1.03e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSG-TVS---MQKGL--------RI 68
Cdd:COG1119 1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRlfgERRGGedvwelrkRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 69 GYL--AQQGELTGEETVLETlesvfepqrrmeaelrsleqemaesgsdpealrILGGKYDT--LTREFERSNgygwRSSV 144
Cdd:COG1119 81 GLVspALQLRFPRDETVLDV---------------------------------VLSGFFDSigLYREPTDEQ----RERA 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 145 QGVLAGLELREFQDMKTGLLSGGERTRLCLGR----------MlltepdllllDEPTNHLDLKSIAWLEEYLAAFHG--- 211
Cdd:COG1119 124 RELLELLGLAHLADRPFGTLSQGEQRRVLIARalvkdpelliL----------DEPTAGLDLGARELLLALLDKLAAega 193
|
....*...
gi 1226689869 212 -AVLVISH 218
Cdd:COG1119 194 pTLVLVTH 201
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
9-239 |
1.27e-11 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 66.65 E-value: 1.27e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 9 VKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ---------KGLRIGYLAQQGELTG 79
Cdd:PRK10851 8 IKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHgtdvsrlhaRDRKVGFVFQHYALFR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 80 EETVLETLE---SVFePQRrmeaelrsleqemaesgsdpealrilggkydtltrefERSNGYGWRSSVQGVLAGLELREF 156
Cdd:PRK10851 88 HMTVFDNIAfglTVL-PRR-------------------------------------ERPNAAAIKAKVTQLLEMVQLAHL 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 157 QDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFH-----GAVLViSHDRYFLDRVCGRMA 231
Cdd:PRK10851 130 ADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHeelkfTSVFV-THDQEEAMEVADRVV 208
|
....*...
gi 1226689869 232 ELLLGNVE 239
Cdd:PRK10851 209 VMSQGNIE 216
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
331-520 |
1.38e-11 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 64.31 E-value: 1.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 331 TEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAG--------VIRWGTGV--DLGYYDQHQ 400
Cdd:cd03265 3 VENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGratvaghdVVREPREVrrRIGIVFQDL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 S---EL--HENKTVLDEVWDrFPRMEQYEVRGALGLFLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNH 475
Cdd:cd03265 83 SvddELtgWENLYIHARLYG-VPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIG 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1226689869 476 LDMDSR----EALENALSDFPGTIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:cd03265 162 LDPQTRahvwEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRI 210
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
6-195 |
1.48e-11 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 64.65 E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 6 LQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ---------------KGLR--I 68
Cdd:COG4161 5 LKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAghqfdfsqkpsekaiRLLRqkV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 69 GYLAQQGELTGEETVLETLesvfepqrrMEAELRSLEQEMAESgsdpealrilggkydtltrefersngygwRSSVQGVL 148
Cdd:COG4161 85 GMVFQQYNLWPHLTVMENL---------IEAPCKVLGLSKEQA-----------------------------REKAMKLL 126
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1226689869 149 AGLELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD 195
Cdd:COG4161 127 ARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALD 173
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
338-507 |
1.52e-11 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 63.82 E-value: 1.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 338 YGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVI---RWGTGVDLGYYDQ------HQSELHENKT 408
Cdd:PRK13540 11 YHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEIlfeRQSIKKDLCTYQKqlcfvgHRSGINPYLT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 409 VLDEVWdrfprMEQYEVRGALGL----FLFTGDEVFE-PVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREA 483
Cdd:PRK13540 91 LRENCL-----YDIHFSPGAVGItelcRLFSLEHLIDyPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLT 165
|
170 180
....*....|....*....|....*..
gi 1226689869 484 LENALSDFP---GTIISVSHDRYFINR 507
Cdd:PRK13540 166 IITKIQEHRakgGAVLLTSHQDLPLNK 192
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
3-60 |
1.61e-11 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 66.51 E-value: 1.61e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:PRK09452 14 LVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRI 71
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
329-522 |
1.69e-11 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 65.01 E-value: 1.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIrWGTGVDLGYYDQHQSE-----L 403
Cdd:PRK10253 8 LRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHV-WLDGEHIQHYASKEVArriglL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 404 HENKT-----VLDEVWDR--------FPRMEQYEVRGALGLFLFTG--DEVFEPVSTLSGGEKGRVALTELMLRKDNVLL 468
Cdd:PRK10253 87 AQNATtpgdiTVQELVARgryphqplFTRWRKEDEEAVTKAMQATGitHLADQSVDTLSGGQRQRAWIAMVLAQETAIML 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 469 LDEPTNHLDMDSREALENALSDFPG----TIISVSHDRYFINRFAEKVWVL-DGNEIKE 522
Cdd:PRK10253 167 LDEPTTWLDISHQIDLLELLSELNRekgyTLAAVLHDLNQACRYASHLIALrEGKIVAQ 225
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
4-218 |
2.09e-11 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 62.79 E-value: 2.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVkkSF----GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM---------QKGLR--I 68
Cdd:cd03228 1 IEFKNV--SFsypgRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIdgvdlrdldLESLRknI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 69 GYLAQqgeltgeETVLetlesvFEpqrrmeaelrsleqemaesgsdpealrilggkyDTLtrefeRSNgygwrssvqgvl 148
Cdd:cd03228 79 AYVPQ-------DPFL------FS---------------------------------GTI-----REN------------ 95
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 149 aglelrefqdmktgLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG--AVLVISH 218
Cdd:cd03228 96 --------------ILSGGQRQRIAIARALLRDPPILILDEATSALDPETEALILEALRALAKgkTVIVIAH 153
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
14-218 |
2.12e-11 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 63.00 E-value: 2.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 14 GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-----------SMQKGLRIGYLAQQGELtgeet 82
Cdd:cd03246 13 AEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVrldgadisqwdPNELGDHVGYLPQDDEL----- 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 vletlesvFepqrrmeaelrsleqemaeSGSDPEAlrilggkydtltrefersngygwrssvqgvlaglelrefqdmktg 162
Cdd:cd03246 88 --------F-------------------SGSIAEN--------------------------------------------- 95
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 163 LLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGA---VLVISH 218
Cdd:cd03246 96 ILSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQAIAALKAAgatRIVIAH 154
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
329-522 |
2.22e-11 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 64.61 E-value: 2.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVI----------RWGTGvDLGYYDQ 398
Cdd:PRK10619 6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIvvngqtinlvRDKDG-QLKVADK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 399 HQSEL----------HEN----KTVLDEVWD---RFPRMEQYEVRGALGLFL----FTGDEVFEPVSTLSGGEKGRVALT 457
Cdd:PRK10619 85 NQLRLlrtrltmvfqHFNlwshMTVLENVMEapiQVLGLSKQEARERAVKYLakvgIDERAQGKYPVHLSGGQQQRVSIA 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 458 ELMLRKDNVLLLDEPTNHLDMD-SREALE--NALSDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKE 522
Cdd:PRK10619 165 RALAMEPEVLLFDEPTSALDPElVGEVLRimQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEE 232
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
326-516 |
2.39e-11 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 64.87 E-value: 2.39e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 326 DDVLMTEGLSKGYGDRI-LFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQSELH 404
Cdd:PRK13636 3 DYILKVEELNYNYSDGThALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFD-GKPIDYSRKGLMKLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 405 ENKTVLDEVWD-------------------RFPRME-QYEVRGALGLflfTGDEVF--EPVSTLSGGEKGRVALTELMLR 462
Cdd:PRK13636 82 ESVGMVFQDPDnqlfsasvyqdvsfgavnlKLPEDEvRKRVDNALKR---TGIEHLkdKPTHCLSFGQKKRVAIAGVLVM 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 463 KDNVLLLDEPTNHLD-MDSREALENALSDFPG---TIISVSHDRYFINRFAEKVWVLD 516
Cdd:PRK13636 159 EPKVLVLDEPTAGLDpMGVSEIMKLLVEMQKElglTIIIATHDIDIVPLYCDNVFVMK 216
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
2-229 |
2.52e-11 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 63.89 E-value: 2.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 2 IILALQD-VKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkGL-----RIGYLAQQG 75
Cdd:cd03267 19 LIGSLKSlFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVA-GLvpwkrRKKFLRRIG 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 76 ELTGEETVLETLESVFepqrrmeaelrsleqemaesgsdpEALRILGGKYDTLTREFersngygwRSSVQGVLAGLELRE 155
Cdd:cd03267 98 VVFGQKTQLWWDLPVI------------------------DSFYLLAAIYDLPPARF--------KKRLDELSELLDLEE 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 156 FQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAF---HGA-VLVISHDRYFLDRVCGR 229
Cdd:cd03267 146 LLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYnreRGTtVLLTSHYMKDIEALARR 223
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
3-60 |
2.80e-11 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 66.20 E-value: 2.80e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:COG3845 5 ALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEI 62
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
334-502 |
2.90e-11 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 65.63 E-value: 2.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 334 LSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYDQHQS---------ELH 404
Cdd:PRK11607 25 LTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIML-DGVDLSHVPPYQRpinmmfqsyALF 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 405 ENKTVLDEV-----WDRFPRME-QYEVRGALGLFLFTGDEVFEPvSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDM 478
Cdd:PRK11607 104 PHMTVEQNIafglkQDKLPKAEiASRVNEMLGLVHMQEFAKRKP-HQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDK 182
|
170 180
....*....|....*....|....*...
gi 1226689869 479 DSREALENALSDF----PGTIISVSHDR 502
Cdd:PRK11607 183 KLRDRMQLEVVDIlervGVTCVMVTHDQ 210
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
339-522 |
3.56e-11 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 62.93 E-value: 3.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 339 GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVE--KPDAGVIrwgtgvdlgyydqhqseLHENKTVLDevwdr 416
Cdd:cd03217 11 GGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEI-----------------LFKGEDITD----- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 417 fprMEQYEvRGALGLFL-FTGDEVFEPVST----------LSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALE 485
Cdd:cd03217 69 ---LPPEE-RARLGIFLaFQYPPEIPGVKNadflryvnegFSGGEKKRNEILQLLLLEPDLAILDEPDSGLDIDALRLVA 144
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1226689869 486 NALSDF--PGT-IISVSHDRYFINRF-AEKVWVL-DGNEIKE 522
Cdd:cd03217 145 EVINKLreEGKsVLIITHYQRLLDYIkPDRVHVLyDGRIVKS 186
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
328-515 |
3.58e-11 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 63.88 E-value: 3.58e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGV----EKPDAGVIRWGTGVD----------- 392
Cdd:PRK09984 4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgdKSAGSHIELLGRTVQregrlardirk 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 393 ----LGYYDQhQSELHENKTVLDEV----------WDR----FPRMEQYEVRGAL---GLFLFTgdevFEPVSTLSGGEK 451
Cdd:PRK09984 84 sranTGYIFQ-QFNLVNRLSVLENVligalgstpfWRTcfswFTREQKQRALQALtrvGMVHFA----HQRVSTLSGGQQ 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 452 GRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPG----TIISVSHDRYFINRFAEKVWVL 515
Cdd:PRK09984 159 QRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQndgiTVVVTLHQVDYALRYCERIVAL 226
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
326-502 |
3.63e-11 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 65.13 E-value: 3.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 326 DDVLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIrWGTGVDLgyydQHQSELHE 405
Cdd:PRK11432 4 KNFVVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQI-FIDGEDV----THRSIQQR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 NKTVLDEVWDRFPRMEQYE-------------------VRGALGLFLFTGdevFEP--VSTLSGGEKGRVALTELMLRKD 464
Cdd:PRK11432 79 DICMVFQSYALFPHMSLGEnvgyglkmlgvpkeerkqrVKEALELVDLAG---FEDryVDQISGGQQQRVALARALILKP 155
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1226689869 465 NVLLLDEPTNHLDMDSREALENALSD----FPGTIISVSHDR 502
Cdd:PRK11432 156 KVLLFDEPLSNLDANLRRSMREKIRElqqqFNITSLYVTHDQ 197
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
328-501 |
3.68e-11 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 63.61 E-value: 3.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDR-----ILfRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYD----- 397
Cdd:COG4181 8 IIELRGLTKTVGTGageltIL-KGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLA-GQDLFALDedara 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 398 ----QH-----QSE-LHENKTVLDEVwdrfprMEQYEVRGALGLFLfTGDEVFEPV----------STLSGGEKGRVALT 457
Cdd:COG4181 86 rlraRHvgfvfQSFqLLPTLTALENV------MLPLELAGRRDARA-RARALLERVglghrldhypAQLSGGEQQRVALA 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1226689869 458 ELMLRKDNVLLLDEPTNHLDMDSREALENAL----SDFPGTIISVSHD 501
Cdd:COG4181 159 RAFATEPAILFADEPTGNLDAATGEQIIDLLfelnRERGTTLVLVTHD 206
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
4-176 |
3.76e-11 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 63.22 E-value: 3.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ----KGLR--------IGYL 71
Cdd:cd03224 1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDgrdiTGLPpheraragIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 72 AQQGELTGEETVLETLESVFEPQRRMEAElRSLEqemaesgsdpealRILGgkydtltrEFERsngygwrssvqgvlagl 151
Cdd:cd03224 81 PEGRRIFPELTVEENLLLGAYARRRAKRK-ARLE-------------RVYE--------LFPR----------------- 121
|
170 180
....*....|....*....|....*
gi 1226689869 152 eLREFQDMKTGLLSGGERTRLCLGR 176
Cdd:cd03224 122 -LKERRKQLAGTLSGGEQQMLAIAR 145
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
2-226 |
3.84e-11 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 63.64 E-value: 3.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 2 IILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM-QKGL----------RIGY 70
Cdd:PRK13548 1 AMLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLnGRPLadwspaelarRRAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 71 LAQQGELTGEETVLETLESVFEPQRRMEAELRSL-EQEMAESGsdpealrilggkydtltrefersngygwrssvqgvLA 149
Cdd:PRK13548 81 LPQHSSLSFPFTVEEVVAMGRAPHGLSRAEDDALvAAALAQVD-----------------------------------LA 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 150 GLELREFQDmktglLSGGERTRLCLGRMLLTEPDLLLL------DEPTNHLDLK---SIAWLEEYLAAFHG-AVLVISHD 219
Cdd:PRK13548 126 HLAGRDYPQ-----LSGGEQQRVQLARVLAQLWEPDGPprwlllDEPTSALDLAhqhHVLRLARQLAHERGlAVIVVLHD 200
|
250
....*....|..
gi 1226689869 220 -----RYfLDRV 226
Cdd:PRK13548 201 lnlaaRY-ADRI 211
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
332-509 |
4.02e-11 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 63.56 E-value: 4.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDqhQSEL-------- 403
Cdd:COG4604 5 KNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVD-GLDVATTP--SRELakrlailr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 404 HENK-----TVLDEV-WDRFP----RM---EQYEVRGALGLFLFTG------DEvfepvstLSGGEKGR--VALTelmLR 462
Cdd:COG4604 82 QENHinsrlTVRELVaFGRFPyskgRLtaeDREIIDEAIAYLDLEDladrylDE-------LSGGQRQRafIAMV---LA 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 463 KD-NVLLLDEPTNHLDMD-SRE---ALENALSDFPGTIISVSHDryfINrFA 509
Cdd:COG4604 152 QDtDYVLLDEPLNNLDMKhSVQmmkLLRRLADELGKTVVIVLHD---IN-FA 199
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
2-233 |
4.43e-11 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 63.22 E-value: 4.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 2 IILALQDVKKSFGTHE-------VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGtvsmqkglRIGYLAQQ 74
Cdd:COG4778 3 TLLEVENLSKTFTLHLqggkrlpVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSG--------SILVRHDG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 75 GELT----GEETVLE--------------------TLESVFEPQRRMeaelrsleqemaesGSDPEALRilggkydtltr 130
Cdd:COG4778 75 GWVDlaqaSPREILAlrrrtigyvsqflrviprvsALDVVAEPLLER--------------GVDREEAR----------- 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 131 efERsngygwrssVQGVLAGLELRE---------FqdmktgllSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKS--- 198
Cdd:COG4778 130 --AR---------ARELLARLNLPErlwdlppatF--------SGGEQQRVNIARGFIADPPLLLLDEPTASLDAANrav 190
|
250 260 270
....*....|....*....|....*....|....*..
gi 1226689869 199 -IAWLEEYLAAfhGAVLV-ISHDRYFLDRVCGRMAEL 233
Cdd:COG4778 191 vVELIEEAKAR--GTAIIgIFHDEEVREAVADRVVDV 225
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
8-235 |
5.32e-11 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 64.75 E-value: 5.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 8 DVKKSFGTHEVlkSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM--------QKGL-------RIGYLA 72
Cdd:TIGR02142 4 RFSKRLGDFSL--DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLngrtlfdsRKGIflppekrRIGYVF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 73 QQGELTGEETVLETLESVFepqRRMEAELRSLeqemaesgSDPEALRILGgkydtltrefersngygwrssvqgvlagle 152
Cdd:TIGR02142 82 QEARLFPHLSVRGNLRYGM---KRARPSERRI--------SFERVIELLG------------------------------ 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 153 LREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKS----IAWLEEYLAAFHGAVLVISHDryfLDRVcG 228
Cdd:TIGR02142 121 IGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRkyeiLPYLERLHAEFGIPILYVSHS---LQEV-L 196
|
....*..
gi 1226689869 229 RMAELLL 235
Cdd:TIGR02142 197 RLADRVV 203
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
358-517 |
5.83e-11 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 64.35 E-value: 5.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 358 ALIGDNGTGKSTLLQCLIGVEKPDAGVIR-----W---GTGVDL-------GYYDQHQSeLHENKTV---LDEVWDRFPR 419
Cdd:COG4148 29 ALFGPSGSGKTTLLRAIAGLERPDSGRIRlggevLqdsARGIFLpphrrriGYVFQEAR-LFPHLSVrgnLLYGRKRAPR 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 420 MEQY----EVRGALGLflftgdevfEP-----VSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREA----LEN 486
Cdd:COG4148 108 AERRisfdEVVELLGI---------GHlldrrPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEilpyLER 178
|
170 180 190
....*....|....*....|....*....|.
gi 1226689869 487 ALSDFPGTIISVSHDRYFINRFAEKVWVLDG 517
Cdd:COG4148 179 LRDELDIPILYVSHSLDEVARLADHVVLLEQ 209
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
345-501 |
6.13e-11 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 62.87 E-value: 6.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 345 RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAG-VIRWGTGVDLGYYD-----QHQSEL-----HENKTV-LDE 412
Cdd:TIGR01184 2 KGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGgVILEGKQITEPGPDrmvvfQNYSLLpwltvRENIALaVDR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 413 VWDRFPRMEQYE-VRGALGLFLFTgDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENAL--- 488
Cdd:TIGR01184 82 VLPDLSKSERRAiVEEHIALVGLT-EAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEELmqi 160
|
170
....*....|....
gi 1226689869 489 -SDFPGTIISVSHD 501
Cdd:TIGR01184 161 wEEHRVTVLMVTHD 174
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
341-522 |
8.93e-11 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 62.50 E-value: 8.93e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 341 RILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYDQH----------QSELHENKTVL 410
Cdd:cd03252 15 PVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLV-DGHDLALADPAwlrrqvgvvlQENVLFNRSIR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 411 DEVWDRFPRMEQYEVRGALGL-----FLFTGDEVFEPV-----STLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDS 480
Cdd:cd03252 94 DNIALADPGMSMERVIEAAKLagahdFISELPEGYDTIvgeqgAGLSGGQRQRIAIARALIHNPRILIFDEATSALDYES 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1226689869 481 REALENALSDFPG--TIISVSHdRYFINRFAEKVWVLDGNEIKE 522
Cdd:cd03252 174 EHAIMRNMHDICAgrTVIIIAH-RLSTVKNADRIIVMEKGRIVE 216
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
332-517 |
8.95e-11 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 61.05 E-value: 8.95e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMhVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYDQHQSelhenktvld 411
Cdd:cd03222 4 PDCVKRYGVFFLLVELGV-VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEW-DGITPVYKPQYID---------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 412 evwdrfprmeqyevrgalglflftgdevfepvstLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDF 491
Cdd:cd03222 72 ----------------------------------LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRL 117
|
170 180 190
....*....|....*....|....*....|
gi 1226689869 492 ----PGTIISVSHDRYFINRFAEKVWVLDG 517
Cdd:cd03222 118 seegKKTALVVEHDLAVLDYLSDRIHVFEG 147
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
3-252 |
1.23e-10 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 62.34 E-value: 1.23e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVS--------MQKGLRI------ 68
Cdd:PRK09984 4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSAGShiellgrtVQREGRLardirk 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 69 -----GYLAQQGELTGEETVLETLesvfepqrrmeaelrsleqEMAESGSDPealrilggKYDTLTREFERSNgygwRSS 143
Cdd:PRK09984 84 srantGYIFQQFNLVNRLSVLENV-------------------LIGALGSTP--------FWRTCFSWFTREQ----KQR 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 144 VQGVLAGLELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG----AVLVISHD 219
Cdd:PRK09984 133 ALQALTRVGMVHFAHQRVSTLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQndgiTVVVTLHQ 212
|
250 260 270
....*....|....*....|....*....|...
gi 1226689869 220 RYFLDRVCGRMAELLLGNVeTYSGNYTEYLEKR 252
Cdd:PRK09984 213 VDYALRYCERIVALRQGHV-FYDGSSQQFDNER 244
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
338-520 |
1.24e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 62.83 E-value: 1.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 338 YGDRILFrDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVDLGYYDQH----------------QS 401
Cdd:PRK13643 17 FASRALF-DIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKeikpvrkkvgvvfqfpES 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 402 ELHEnKTVLDEV----WDRFPRMEQYEVRGALGLFLFTGDEVFEPVS--TLSGGEKGRVALTELMLRKDNVLLLDEPTNH 475
Cdd:PRK13643 96 QLFE-ETVLKDVafgpQNFGIPKEKAEKIAAEKLEMVGLADEFWEKSpfELSGGQMRRVAIAGILAMEPEVLVLDEPTAG 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1226689869 476 LDMDSR---EALENALSDFPGTIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:PRK13643 175 LDPKARiemMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHI 222
|
|
| LolD_lipo_ex |
TIGR02211 |
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ... |
3-226 |
1.43e-10 |
|
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 61.60 E-value: 1.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFG----THEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-----SMQK-------GL 66
Cdd:TIGR02211 1 LLKCENLGKRYQegklDTRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVlfngqSLSKlssneraKL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 67 R---IGYLAQQGELTGEETVLE--TLESVFEPQRRMEAELRSleQEMAESgsdpealrilggkydtltrefersngygwr 141
Cdd:TIGR02211 81 RnkkLGFIYQFHHLLPDFTALEnvAMPLLIGKKSVKEAKERA--YEMLEK------------------------------ 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 142 ssvqgvlAGLELRefQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKS----IAWLEEYLAAFHGAVLVIS 217
Cdd:TIGR02211 129 -------VGLEHR--INHRPSELSGGERQRVAIARALVNQPSLVLADEPTGNLDNNNakiiFDLMLELNRELNTSFLVVT 199
|
250
....*....|..
gi 1226689869 218 HDRYF---LDRV 226
Cdd:TIGR02211 200 HDLELakkLDRV 211
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
8-230 |
1.43e-10 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 64.04 E-value: 1.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 8 DVKKSFGTHEvLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGtvSMQKGLRIGYLAQQGELTGEETVLETL 87
Cdd:COG1245 346 DLTKSYGGFS-LEVEGGEIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEG--EVDEDLKISYKPQYISPDYDGTVEEFL 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 88 ESVfepqrrmeaelrsLEQEMAESGSDPEALRILGgkydtLTREFERsngygwrssvqgvlaglELREfqdmktglLSGG 167
Cdd:COG1245 423 RSA-------------NTDDFGSSYYKTEIIKPLG-----LEKLLDK-----------------NVKD--------LSGG 459
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 168 ERTRL----CLGRmlltEPDLLLLDEPTNHLDlksiawLEEYLAA----------FHGAVLVISHDRYFLDRVCGRM 230
Cdd:COG1245 460 ELQRVaiaaCLSR----DADLYLLDEPSAHLD------VEQRLAVakairrfaenRGKTAMVVDHDIYLIDYISDRL 526
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
332-523 |
1.83e-10 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 61.55 E-value: 1.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGD-RILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVD------------LGYYDQ 398
Cdd:cd03295 4 ENVTKRYGGgKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFID-GEDireqdpvelrrkIGYVIQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 399 hQSELHENKTVLDEV--------WDRfPRMEQ--YEVRGALGLflftgdevfEPVS-------TLSGGEKGRVALTELML 461
Cdd:cd03295 83 -QIGLFPHMTVEENIalvpkllkWPK-EKIREraDELLALVGL---------DPAEfadryphELSGGQQQRVGVARALA 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 462 RKDNVLLLDEPTNHLDMDSREALENAL----SDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKEY 523
Cdd:cd03295 152 ADPPLLLMDEPFGALDPITRDQLQEEFkrlqQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQV 217
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
346-501 |
1.91e-10 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 62.08 E-value: 1.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 346 DLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIrwgtgvdlgYYDQHQSELHENKTVLDEVWDRFPRME---- 421
Cdd:PRK13648 27 DVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEI---------FYNNQAITDDNFEKLRKHIGIVFQNPDnqfv 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 422 ----QYEVrgALGL--FLFTGDEVFEPVS-----------------TLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDM 478
Cdd:PRK13648 98 gsivKYDV--AFGLenHAVPYDEMHRRVSealkqvdmleradyepnALSGGQKQRVAIAGVLALNPSVIILDEATSMLDP 175
|
170 180
....*....|....*....|....*..
gi 1226689869 479 DSREALENAL----SDFPGTIISVSHD 501
Cdd:PRK13648 176 DARQNLLDLVrkvkSEHNITIISITHD 202
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
4-60 |
2.11e-10 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 61.10 E-value: 2.11e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEI 57
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
6-238 |
2.74e-10 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 60.50 E-value: 2.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 6 LQDVKKSF-GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-------SMQKGLRIGYLAQQGEL 77
Cdd:cd03292 3 FINVTKTYpNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIrvngqdvSDLRGRAIPYLRRKIGV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 78 TGEETVLETLESVFEpqrrmeaelrsleqemaesgSDPEALRILGGKydtlTREfersngygWRSSVQGVLAGLELREFQ 157
Cdd:cd03292 83 VFQDFRLLPDRNVYE--------------------NVAFALEVTGVP----PRE--------IRKRVPAALELVGLSHKH 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 158 DMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGA---VLVISHDRYFLDRVCGRMAELL 234
Cdd:cd03292 131 RALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTTWEIMNLLKKINKAgttVVVATHAKELVDTTRHRVIALE 210
|
....
gi 1226689869 235 LGNV 238
Cdd:cd03292 211 RGKL 214
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
333-520 |
3.14e-10 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 62.35 E-value: 3.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 333 GLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGvirwgtgvDLGYYDQHQSELHENKTVLDE 412
Cdd:PRK11000 8 NVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSG--------DLFIGEKRMNDVPPAERGVGM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 413 VWDRF---PRMEQYEvRGALGLFLFTGD--EVFEPVS-----------------TLSGGEKGRVALTELMLRKDNVLLLD 470
Cdd:PRK11000 80 VFQSYalyPHLSVAE-NMSFGLKLAGAKkeEINQRVNqvaevlqlahlldrkpkALSGGQRQRVAIGRTLVAEPSVFLLD 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 471 EPTNHLDMDSREALENALSDF----PGTIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:PRK11000 159 EPLSNLDAALRVQMRIEISRLhkrlGRTMIYVTHDQVEAMTLADKIVVLDAGRV 212
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
345-523 |
3.26e-10 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 60.59 E-value: 3.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 345 RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQH----------------QSELHENkt 408
Cdd:cd03244 21 KNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILID-GVDISKIGLHdlrsrisiipqdpvlfSGTIRSN-- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 409 vLD--------EVWDRFPRMEQYEVRGALGLFLftGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDS 480
Cdd:cd03244 98 -LDpfgeysdeELWQALERVGLKEFVESLPGGL--DTVVEEGGENLSVGQRQLLCLARALLRKSKILVLDEATASVDPET 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1226689869 481 REALENAL-SDFPG-TIISVSHDRYFINRFaEKVWVLDGNEIKEY 523
Cdd:cd03244 175 DALIQKTIrEAFKDcTVLTIAHRLDTIIDS-DRILVLDKGRVVEF 218
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
331-522 |
3.42e-10 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 60.97 E-value: 3.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 331 TEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYDQHQ---------- 400
Cdd:TIGR02769 14 TGGLFGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSF-RGQDLYQLDRKQrrafrrdvql 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 ------SELHENKTV---LDEVWDRFPRMEQYE-VRGALGLFLFTG--DEVFEPV-STLSGGEKGRVALTELMLRKDNVL 467
Cdd:TIGR02769 93 vfqdspSAVNPRMTVrqiIGEPLRHLTSLDESEqKARIAELLDMVGlrSEDADKLpRQLSGGQLQRINIARALAVKPKLI 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 468 LLDEPTNHLDMDSR----EALENALSDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKE 522
Cdd:TIGR02769 173 VLDEAVSNLDMVLQavilELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVE 231
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
332-515 |
4.21e-10 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 60.07 E-value: 4.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDR----ILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVI--------------RWGTGV-- 391
Cdd:cd03266 5 DALTKRFRDVkktvQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFAtvdgfdvvkepaeaRRRLGFvs 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 392 -------------DLGYY-DQHQSELHENKTVLDEVWDRFpRMEQYEVRgalglflftgdevfePVSTLSGGEKGRVALT 457
Cdd:cd03266 85 dstglydrltareNLEYFaGLYGLKGDELTARLEELADRL-GMEELLDR---------------RVGGFSTGMRQKVAIA 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 458 ELMLRKDNVLLLDEPTNHLDMDSREALEN---ALSDFPGTIISVSHDRYFINRFAEKVWVL 515
Cdd:cd03266 149 RALVHDPPVLLLDEPTTGLDVMATRALREfirQLRALGKCILFSTHIMQEVERLCDRVVVL 209
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
329-472 |
4.29e-10 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 60.25 E-value: 4.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVD-------------LGY 395
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLD-GQDitklpmhkrarlgIGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 396 YDQHQSeLHENKTVLDEV-----WDRFPRMEQYEVRGALgLFLFTGDEVFE-PVSTLSGGEKGRVALTELMLRKDNVLLL 469
Cdd:cd03218 80 LPQEAS-IFRKLTVEENIlavleIRGLSKKEREEKLEEL-LEEFHITHLRKsKASSLSGGERRRVEIARALATNPKFLLL 157
|
...
gi 1226689869 470 DEP 472
Cdd:cd03218 158 DEP 160
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
4-269 |
4.93e-10 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 62.49 E-value: 4.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVkkSF---GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM---------QKGLR--IG 69
Cdd:COG1132 340 IEFENV--SFsypGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIdgvdirdltLESLRrqIG 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 70 YLAQQGEL-TGeeTVLE---------TLESVFEPQRRMEAE--LRSLEQemaesgsdpealrilggKYDTLTREfersng 137
Cdd:COG1132 418 VVPQDTFLfSG--TIREnirygrpdaTDEEVEEAAKAAQAHefIEALPD-----------------GYDTVVGE------ 472
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 138 ygwrssvQGVlaglelrefqdmktgLLSGGERTRLCLGR----------MlltepdllllDEPTNHLDLKSIAWLEEYLA 207
Cdd:COG1132 473 -------RGV---------------NLSGGQRQRIAIARallkdppiliL----------DEATSALDTETEALIQEALE 520
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 208 AF-HGA-VLVISH--------DR-YFLDRvcGRMAElllgnvetySGNYTEyLEKRTTVYEnrmRAWKLQQKE 269
Cdd:COG1132 521 RLmKGRtTIVIAHrlstirnaDRiLVLDD--GRIVE---------QGTHEE-LLARGGLYA---RLYRLQFGE 578
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
3-233 |
5.02e-10 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 59.86 E-value: 5.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-----SMQKGLRIGYLAQQGEL 77
Cdd:PRK13543 11 LLAAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIqidgkTATRGDRSRFMAYLGHL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 78 TGEETVLETLESVFEpqrrmeaeLRSLE----QEMAESgsdpeALRILG--GKYDTLTREfersngygwrssvqgvlagl 151
Cdd:PRK13543 91 PGLKADLSTLENLHF--------LCGLHgrraKQMPGS-----ALAIVGlaGYEDTLVRQ-------------------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 152 elrefqdmktglLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAF---HGAVLVISHDRYFLDRVCG 228
Cdd:PRK13543 138 ------------LSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGITLVNRMISAHlrgGGAALVTTHGAYAAPPVRT 205
|
....*
gi 1226689869 229 RMAEL 233
Cdd:PRK13543 206 RMLTL 210
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
7-218 |
5.12e-10 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 59.79 E-value: 5.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 7 QDVKKSFGT---HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkGLRIG-----YLAQQGELT 78
Cdd:cd03248 15 QNVTFAYPTrpdTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLD-GKPISqyehkYLHSKVSLV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 79 GEETVLETlesvfepqrrmeaelRSLEQEMAesgsdpealrilggkYDTLTREFERSNGYGWRSSVQGVLAGLELREFQD 158
Cdd:cd03248 94 GQEPVLFA---------------RSLQDNIA---------------YGLQSCSFECVKEAAQKAHAHSFISELASGYDTE 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 159 M--KTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG--AVLVISH 218
Cdd:cd03248 144 VgeKGSQLSGGQKQRVAIARALIRNPQVLILDEATSALDAESEQQVQQALYDWPErrTVLVIAH 207
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
332-522 |
5.39e-10 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 62.13 E-value: 5.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVE--KPDAGVIRWGTGV--DLGYYD---------- 397
Cdd:TIGR03269 4 KNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDqyEPTSGRIIYHVALceKCGYVErpskvgepcp 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 398 --------------------------------QHQSELHENKTVLDEVWDRFPRMEqYEVRGALGLFLFTGDEV------ 439
Cdd:TIGR03269 84 vcggtlepeevdfwnlsdklrrrirkriaimlQRTFALYGDDTVLDNVLEALEEIG-YEGKEAVGRAVDLIEMVqlshri 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 440 FEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDS----REALENALSDFPGTIISVSHDRYFINRFAEKVWVL 515
Cdd:TIGR03269 163 THIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTaklvHNALEEAVKASGISMVLTSHWPEVIEDLSDKAIWL 242
|
....*..
gi 1226689869 516 DGNEIKE 522
Cdd:TIGR03269 243 ENGEIKE 249
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
333-502 |
5.73e-10 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 61.50 E-value: 5.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 333 GLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQSELHenkTVLdE 412
Cdd:PRK09452 19 GISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLD-GQDITHVPAENRHVN---TVF-Q 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 413 VWDRFPRMEQYE-VrgALGLFL--FTGDEVFEPV-----------------STLSGGEKGRVALTELMLRKDNVLLLDEP 472
Cdd:PRK09452 94 SYALFPHMTVFEnV--AFGLRMqkTPAAEITPRVmealrmvqleefaqrkpHQLSGGQQQRVAIARAVVNKPKVLLLDES 171
|
170 180 190
....*....|....*....|....*....|....
gi 1226689869 473 TNHLDMDSREALENALSDFPG----TIISVSHDR 502
Cdd:PRK09452 172 LSALDYKLRKQMQNELKALQRklgiTFVFVTHDQ 205
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
6-528 |
5.85e-10 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 62.11 E-value: 5.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 6 LQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQK------------GLRIGYLAQ 73
Cdd:PRK09700 8 MAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNinynkldhklaaQLGIGIIYQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 74 QGELTGEETVLETLESVFEPQRRM-------EAELRSLEQEMaesgsdpeaLRILGGKYDTltrefersngygwrssvqg 146
Cdd:PRK09700 88 ELSVIDELTVLENLYIGRHLTKKVcgvniidWREMRVRAAMM---------LLRVGLKVDL------------------- 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 147 vlaglelrefqDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG---AVLVISHDRYFL 223
Cdd:PRK09700 140 -----------DEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKegtAIVYISHKLAEI 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 224 DRVCGRmaelllgnvetysgnYTeYLEKRTTVYENRMrawklqqKEIARQEAIIAMYRRfnkeksiRIANSKQKRLDMVE 303
Cdd:PRK09700 209 RRICDR---------------YT-VMKDGSSVCSGMV-------SDVSNDDIVRLMVGR-------ELQNRFNAMKENVS 258
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 304 RLEkpedestirfrfetrrrtGDDVLMTEGLSKgyGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAG 383
Cdd:PRK09700 259 NLA------------------HETVFEVRNVTS--RDRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGG 318
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 384 VIrWGTGVDL-------------GYYDQHQSE--------LHENKTVLDEV--------WDRF-PRMEQYEVRGALGLFL 433
Cdd:PRK09700 319 EI-RLNGKDIsprspldavkkgmAYITESRRDngffpnfsIAQNMAISRSLkdggykgaMGLFhEVDEQRTAENQRELLA 397
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 434 FTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSRE---ALENALSDFPGTIISVSHDRYFINRFAE 510
Cdd:PRK09700 398 LKCHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAeiyKVMRQLADDGKVILMVSSELPEIITVCD 477
|
570
....*....|....*...
gi 1226689869 511 KVWVLDGNEIKEYLGNYD 528
Cdd:PRK09700 478 RIAVFCEGRLTQILTNRD 495
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
328-515 |
6.25e-10 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 59.10 E-value: 6.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYgdRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIG--VEKPDAGVIRW-GTGVDL-------GYYD 397
Cdd:cd03213 11 VTVKSSPSKSG--KQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLInGRPLDKrsfrkiiGYVP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 398 QHQSeLHENKTVLDEVwdrfprMEQYEVRGalglflftgdevfepvstLSGGEKGRVALTELMLRKDNVLLLDEPTNHLd 477
Cdd:cd03213 89 QDDI-LHPTLTVRETL------MFAAKLRG------------------LSGGERKRVSIALELVSNPSLLFLDEPTSGL- 142
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1226689869 478 mDSREALE-----NALSDFPGTIISVSHD-RYFINRFAEKVWVL 515
Cdd:cd03213 143 -DSSSALQvmsllRRLADTGRTIICSIHQpSSEIFELFDKLLLL 185
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
328-479 |
6.59e-10 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 59.48 E-value: 6.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVD--------------L 393
Cdd:PRK13543 11 LLAAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTAtrgdrsrfmaylghL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 394 GYYDQHQSELhENKTVLDEVWDRFPRMEQyevRGALGLFLFTGDEVfEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPT 473
Cdd:PRK13543 91 PGLKADLSTL-ENLHFLCGLHGRRAKQMP---GSALAIVGLAGYED-TLVRQLSAGQKKRLALARLWLSPAPLWLLDEPY 165
|
....*.
gi 1226689869 474 NHLDMD 479
Cdd:PRK13543 166 ANLDLE 171
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
351-517 |
7.72e-10 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 59.41 E-value: 7.72e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 351 VRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYDQHQSELHENKTV---------------LDEVW- 414
Cdd:PRK10584 33 VKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSL-VGQPLHQMDEEARAKLRAKHVgfvfqsfmliptlnaLENVEl 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 415 --------DRFPRMEQYEVRGALGLflftGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALEN 486
Cdd:PRK10584 112 pallrgesSRQSRNGAKALLEQLGL----GKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIAD 187
|
170 180 190
....*....|....*....|....*....|....*
gi 1226689869 487 AL----SDFPGTIISVSHDRYFINRFAEKVWVLDG 517
Cdd:PRK10584 188 LLfslnREHGTTLILVTHDLQLAARCDRRLRLVNG 222
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
3-195 |
9.60e-10 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 59.34 E-value: 9.60e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsMQKGLRI-------------- 68
Cdd:PRK09493 1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDL-IVDGLKVndpkvderlirqea 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 69 GYLAQQGELTGEETVLETLesVFEPQRrmeaeLRSLEQEMAEsgsdpealrilggkydTLTREfersngygwrssvqgVL 148
Cdd:PRK09493 80 GMVFQQFYLFPHLTALENV--MFGPLR-----VRGASKEEAE----------------KQARE---------------LL 121
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1226689869 149 AGLELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD 195
Cdd:PRK09493 122 AKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSALD 168
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
347-529 |
1.32e-09 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 61.01 E-value: 1.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 347 LKMHVRAGDRIALIGDNGTGKSTLLQCLIGVeKPDAGVIRWGtGV-----DLGYYDQHQSELHEN-----KTVLDEVWDR 416
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTSLLNALLGF-LPYQGSLKIN-GIelrelDPESWRKHLSWVGQNpqlphGTLRDNVLLG 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 417 FPRMEQYEVRGAL--------------GLFLFTGDEVfepvSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSRE 482
Cdd:PRK11174 447 NPDASDEQLQQALenawvseflpllpqGLDTPIGDQA----AGLSVGQAQRLALARALLQPCQLLLLDEPTASLDAHSEQ 522
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1226689869 483 ALENALSDFPG--TIISVSHDRYFINRFaEKVWVLDGNEIKEYlGNYDS 529
Cdd:PRK11174 523 LVMQALNAASRrqTTLMVTHQLEDLAQW-DQIWVMQDGQIVQQ-GDYAE 569
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
341-477 |
1.49e-09 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 59.33 E-value: 1.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 341 RILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHQSELH---------------- 404
Cdd:COG1101 19 KRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILID-GKDVTKLPEYKRAKYigrvfqdpmmgtapsm 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 405 ---EN--------------KTVLDEVWDRFprMEQYEVRGaLGLflftGDEVFEPVSTLSGGEkgRVALTELM--LRKDN 465
Cdd:COG1101 98 tieENlalayrrgkrrglrRGLTKKRRELF--RELLATLG-LGL----ENRLDTKVGLLSGGQ--RQALSLLMatLTKPK 168
|
170
....*....|..
gi 1226689869 466 VLLLDEPTNHLD 477
Cdd:COG1101 169 LLLLDEHTAALD 180
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
8-230 |
1.56e-09 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 60.98 E-value: 1.56e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 8 DVKKSFGTHEvLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSmqKGLRIGYLAQQGELTGEETVletl 87
Cdd:PRK13409 345 DLTKKLGDFS-LEVEGGEIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVD--PELKISYKPQYIKPDYDGTV---- 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 88 esvfepqrrmEAELRSLEQEMAESGSDPEALRILGgkydtLTREFERsngygwrssvqgvlaglELREfqdmktglLSGG 167
Cdd:PRK13409 418 ----------EDLLRSITDDLGSSYYKSEIIKPLQ-----LERLLDK-----------------NVKD--------LSGG 457
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 168 ERTRL----CLGRmlltEPDLLLLDEPTNHLDlksiawLEEYLAA----------FHGAVLVISHDRYFLDRVCGRM 230
Cdd:PRK13409 458 ELQRVaiaaCLSR----DADLYLLDEPSAHLD------VEQRLAVakairriaeeREATALVVDHDIYMIDYISDRL 524
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
356-520 |
1.61e-09 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 59.43 E-value: 1.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 356 RIALIGDNGTGKSTLLQCLIGVEKPDAG-VIRWGTGVDlgyydqhQSELHENKTVL--------DEVWDrfPRMEQYEVR 426
Cdd:PRK13652 32 RIAVIGPNGAGKSTLFRHFNGILKPTSGsVLIRGEPIT-------KENIREVRKFVglvfqnpdDQIFS--PTVEQDIAF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 427 GALGLFLFTG------DEVFEPVST----------LSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSD 490
Cdd:PRK13652 103 GPINLGLDEEtvahrvSSALHMLGLeelrdrvphhLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLND 182
|
170 180 190
....*....|....*....|....*....|....
gi 1226689869 491 FPG----TIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:PRK13652 183 LPEtygmTVIFSTHQLDLVPEMADYIYVMDKGRI 216
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
351-501 |
1.88e-09 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 58.92 E-value: 1.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 351 VRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVI----RWGTGVDlgYYdqHQSELHENKTVLDEVWDRFPRMEQY--- 423
Cdd:cd03236 23 PREGQVLGLVGPNGIGKSTALKILAGKLKPNLGKFddppDWDEILD--EF--RGSELQNYFTKLLEGDVKVIVKPQYvdl 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 424 ---EVRGALGLFLFTGDE----------------VFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSR--- 481
Cdd:cd03236 99 ipkAVKGKVGELLKKKDErgkldelvdqlelrhvLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRlna 178
|
170 180
....*....|....*....|
gi 1226689869 482 EALENALSDFPGTIISVSHD 501
Cdd:cd03236 179 ARLIRELAEDDNYVLVVEHD 198
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
328-473 |
2.04e-09 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 60.43 E-value: 2.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYG-----DRIlfrDLKmhVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW-GTGVDL-------- 393
Cdd:COG3845 5 ALELRGITKRFGgvvanDDV---SLT--VRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIdGKPVRIrsprdaia 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 394 ---GYYDQHQSeLHENKTVLD-------EVWDRFPRMEQY-----EVRGALGLFLftgdEVFEPVSTLSGGEKGRVALTE 458
Cdd:COG3845 80 lgiGMVHQHFM-LVPNLTVAEnivlglePTKGGRLDRKAArarirELSERYGLDV----DPDAKVEDLSVGEQQRVEILK 154
|
170
....*....|....*
gi 1226689869 459 LMLRKDNVLLLDEPT 473
Cdd:COG3845 155 ALYRGARILILDEPT 169
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
346-521 |
2.08e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 59.07 E-value: 2.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 346 DLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWG-------TG----------VDLgYYDQHQSELHENkT 408
Cdd:PRK13641 25 NISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAgyhitpeTGnknlkklrkkVSL-VFQFPEAQLFEN-T 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 409 VLDEVW---DRFPRMEQYEVRGALGLFLFTG--DEV-----FEpvstLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDM 478
Cdd:PRK13641 103 VLKDVEfgpKNFGFSEDEAKEKALKWLKKVGlsEDLiskspFE----LSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDP 178
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1226689869 479 DSREALENALSDFPG---TIISVSHDRYFINRFAEKVWVLD-GNEIK 521
Cdd:PRK13641 179 EGRKEMMQLFKDYQKaghTVILVTHNMDDVAEYADDVLVLEhGKLIK 225
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
6-195 |
2.12e-09 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 58.49 E-value: 2.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 6 LQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM------------QKGLR-----I 68
Cdd:PRK11124 5 LNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIagnhfdfsktpsDKAIRelrrnV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 69 GYLAQQGELTGEETVLETLesvfepqrrMEAELRSLeqEMAESGSDPEALRIlggkydtltrefersngygwrssvqgvL 148
Cdd:PRK11124 85 GMVFQQYNLWPHLTVQQNL---------IEAPCRVL--GLSKDQALARAEKL---------------------------L 126
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1226689869 149 AGLELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD 195
Cdd:PRK11124 127 ERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALD 173
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
4-219 |
2.80e-09 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 57.58 E-value: 2.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLE-----TADSGTVSM-------QKGLRIGYL 71
Cdd:cd03260 1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNdlipgAPDEGEVLLdgkdiydLDVDVLELR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 72 AQQGELTGEETVLETleSVFE-----PQRRMEAELRSLEQEMAEsgsdpeALRILGgkydtLTREFERSngygwrssvqg 146
Cdd:cd03260 81 RRVGMVFQKPNPFPG--SIYDnvaygLRLHGIKLKEELDERVEE------ALRKAA-----LWDEVKDR----------- 136
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 147 vLAGLELrefqdmktgllSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG--AVLVISHD 219
Cdd:cd03260 137 -LHALGL-----------SGGQQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKeyTIVIVTHN 199
|
|
| ABC_tran_CTD |
pfam16326 |
ABC transporter C-terminal domain; This domain is found at the C-terminus of ABC transporters. ... |
569-631 |
3.07e-09 |
|
ABC transporter C-terminal domain; This domain is found at the C-terminus of ABC transporters. It has a coiled coil structure with an atypical 3(10)-helix in the alpha-hairpin region. It is involved in DNA_binding.
Pssm-ID: 465095 [Multi-domain] Cd Length: 69 Bit Score: 53.62 E-value: 3.07e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 569 QKEaLKAAEQAIARAEKEAGEMEAELADPEIWKDPDKAAETTRRYNALKDEIERLYEQYDALE 631
Cdd:pfam16326 7 QRE-LEELEAEIEKLEEEIAELEAQLADPELYSDYEKLQELSAELEELEAELEELYERWEELE 68
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
15-61 |
3.22e-09 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 58.95 E-value: 3.22e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1226689869 15 THEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVS 61
Cdd:COG4586 34 EVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
358-513 |
4.03e-09 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 56.85 E-value: 4.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 358 ALIGDNGTGKSTLLQCLIgvekpdagVIRWGTGVDLGYYDQHQSELHENKTVLDEVWDRF--PRMEQYEVRGALGLFL-- 433
Cdd:cd03240 26 LIVGQNGAGKTTIIEALK--------YALTGELPPNSKGGAHDPKLIREGEVRAQVKLAFenANGKKYTITRSLAILEnv 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 434 -FTGDE-----VFEPVSTLSGGEKG------RVALTELMLRKDNVLLLDEPTNHLDMDSR-----EALENALSDFPGTII 496
Cdd:cd03240 98 iFCHQGesnwpLLDMRGRCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEENIeeslaEIIEERKSQKNFQLI 177
|
170
....*....|....*..
gi 1226689869 497 SVSHDRYFINRfAEKVW 513
Cdd:cd03240 178 VITHDEELVDA-ADHIY 193
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
3-231 |
4.08e-09 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 59.43 E-value: 4.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSF-----GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKG------------ 65
Cdd:TIGR03269 279 IIKVRNVSKRYisvdrGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRVGdewvdmtkpgpd 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 66 LR------IGYLAQQGELTGEETVLETLesvfepqrrmeAELRSLEQemaesgsdPEALRILGGKYDTLTREFERSngyg 139
Cdd:TIGR03269 359 GRgrakryIGILHQEYDLYPHRTVLDNL-----------TEAIGLEL--------PDELARMKAVITLKMVGFDEE---- 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 140 wrssvqgvlaglELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD-----------LKSIAWLEEylaa 208
Cdd:TIGR03269 416 ------------KAEEILDKYPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDpitkvdvthsiLKAREEMEQ---- 479
|
250 260
....*....|....*....|...
gi 1226689869 209 fhgAVLVISHDRYFLDRVCGRMA 231
Cdd:TIGR03269 480 ---TFIIVSHDMDFVLDVCDRAA 499
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
325-523 |
4.33e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 57.75 E-value: 4.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 325 GDDVLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCL---IGVE----KPDAGVIRWGTGVdlgyYD 397
Cdd:PRK14246 7 AEDVFNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLnrlIEIYdskiKVDGKVLYFGKDI----FQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 398 QHQSELHENKTVLDEVWDRFPRMEQY-----------------------EVRGALGLFLFTGDEVFEPVSTLSGGEKGRV 454
Cdd:PRK14246 83 IDAIKLRKEVGMVFQQPNPFPHLSIYdniayplkshgikekreikkiveECLRKVGLWKEVYDRLNSPASQLSGGQQQRL 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 455 ALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPG--TIISVSHDRYFINRFAEKVWVLDGNEIKEY 523
Cdd:PRK14246 163 TIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNeiAIVIVSHNPQQVARVADYVAFLYNGELVEW 233
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1-60 |
4.55e-09 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 58.55 E-value: 4.55e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 1 MIilALQDVKKSF----GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:COG1135 1 MI--ELENLSKTFptkgGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSV 62
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
345-501 |
4.71e-09 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 59.35 E-value: 4.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 345 RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIR-WGTGVD--------------LGYYDQ------HQSEL 403
Cdd:PRK10535 25 KGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRvAGQDVAtldadalaqlrrehFGFIFQryhllsHLTAA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 404 HeNKTVlDEVWDRFPRMEQYEVRGALGLFLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSRE- 482
Cdd:PRK10535 105 Q-NVEV-PAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEe 182
|
170 180
....*....|....*....|.
gi 1226689869 483 --ALENALSDFPGTIISVSHD 501
Cdd:PRK10535 183 vmAILHQLRDRGHTVIIVTHD 203
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
326-520 |
4.75e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 57.89 E-value: 4.75e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 326 DDVLMTEGLSKGYGD--RILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDA---------GV-----IRWGT 389
Cdd:PRK13640 3 DNIVEFKHVSFTYPDskKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDnpnskitvdGItltakTVWDI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 390 GVDLGYYDQHQSELHENKTVLDEVW----DR-FPRMEQYE-VRGALGLFLFTGDEVFEPvSTLSGGEKGRVALTELMLRK 463
Cdd:PRK13640 83 REKVGIVFQNPDNQFVGATVGDDVAfgleNRaVPRPEMIKiVRDVLADVGMLDYIDSEP-ANLSGGQKQRVAIAGILAVE 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 464 DNVLLLDEPTNHLDMDSREAL---------ENALsdfpgTIISVSHDryfINR--FAEKVWVLDGNEI 520
Cdd:PRK13640 162 PKIIILDESTSMLDPAGKEQIlklirklkkKNNL-----TVISITHD---IDEanMADQVLVLDDGKL 221
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
346-501 |
5.07e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 57.82 E-value: 5.07e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 346 DLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVI-----------RWGTGVDLGYYDQHQSELHENKTVLDEVW 414
Cdd:PRK13650 25 DVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIiidgdllteenVWDIRHKIGMVFQNPDNQFVGATVEDDVA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 415 -----DRFPRMEQYE-VRGALGLFLFTGDEVFEPvSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREAL---- 484
Cdd:PRK13650 105 fglenKGIPHEEMKErVNEALELVGMQDFKEREP-ARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELikti 183
|
170
....*....|....*..
gi 1226689869 485 ENALSDFPGTIISVSHD 501
Cdd:PRK13650 184 KGIRDDYQMTVISITHD 200
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
1-191 |
5.10e-09 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 57.30 E-value: 5.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ----KGLR--------I 68
Cdd:COG0410 1 MPMLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDgediTGLPphriarlgI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 69 GYLAQQGELTGEETVLETLesvfepqrRMEAELRSLEQEMAEsgsDPEALrilggkYDTltreFERsngygwrssvqgvl 148
Cdd:COG0410 81 GYVPEGRRIFPSLTVEENL--------LLGAYARRDRAEVRA---DLERV------YEL----FPR-------------- 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 149 agleLREFQDMKTGLLSGGERTRLCLGR---------MlltepdlllLDEPT 191
Cdd:COG0410 126 ----LKERRRQRAGTLSGGEQQMLAIGRalmsrpkllL---------LDEPS 164
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
3-197 |
6.15e-09 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 58.31 E-value: 6.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSmqkglrigylaqqgeLTGEEt 82
Cdd:PRK11607 19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIM---------------LDGVD- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 vletLESVFEPQRRMEAELRS--------LEQEMAesgsdpealriLGGKYDTLTREfersngyGWRSSVQGVLAGLELR 154
Cdd:PRK11607 83 ----LSHVPPYQRPINMMFQSyalfphmtVEQNIA-----------FGLKQDKLPKA-------EIASRVNEMLGLVHMQ 140
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1226689869 155 EFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLK 197
Cdd:PRK11607 141 EFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKK 183
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
3-236 |
6.36e-09 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 56.71 E-value: 6.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHE----VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM------------QKGL 66
Cdd:PRK10584 6 IVEVHHLKKSVGQGEhelsILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLvgqplhqmdeeaRAKL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 67 R---IGYLAQQGELTgeeTVLETLESVFEPqrrmeAELRSleqemaesgsdpealrilggkydtltrEFERSNgygwRSS 143
Cdd:PRK10584 86 RakhVGFVFQSFMLI---PTLNALENVELP-----ALLRG---------------------------ESSRQS----RNG 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 144 VQGVLAGLELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKS---IAWLEEYLAAFHGAVLV-ISHD 219
Cdd:PRK10584 127 AKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTgdkIADLLFSLNREHGTTLIlVTHD 206
|
250
....*....|....*..
gi 1226689869 220 RYFLDRvCGRMAELLLG 236
Cdd:PRK10584 207 LQLAAR-CDRRLRLVNG 222
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
8-219 |
6.74e-09 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 58.19 E-value: 6.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 8 DVKKSFGTHEVlkSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM--------QKGL-------RIGYLA 72
Cdd:COG4148 6 DFRLRRGGFTL--DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLggevlqdsARGIflpphrrRIGYVF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 73 QQGELTGEETVLETLESVfepQRRMEAELRsleqemaesgsdpealrilggkydtltrefersngygwRSSVQGVLAGLE 152
Cdd:COG4148 84 QEARLFPHLSVRGNLLYG---RKRAPRAER--------------------------------------RISFDEVVELLG 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 153 LREFQDMKTGLLSGGERTRLCLGR----------MlltepdllllDEPTNHLDLKS----IAWLEEYLAAFHGAVLVISH 218
Cdd:COG4148 123 IGHLLDRRPATLSGGERQRVAIGRallssprlllM----------DEPLAALDLARkaeiLPYLERLRDELDIPILYVSH 192
|
.
gi 1226689869 219 D 219
Cdd:COG4148 193 S 193
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
8-195 |
8.28e-09 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 55.63 E-value: 8.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 8 DVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGL--ETADSGTV------SMQKGLR--IGYLAQQGEL 77
Cdd:cd03213 14 KSSPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRrtGLGVSGEVlingrpLDKRSFRkiIGYVPQDDIL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 78 TGEETVLETLesvfepqrRMEAELRSLeqemaesgsdpealrilggkydtltrefersngygwrssvqgvlaglelrefq 157
Cdd:cd03213 94 HPTLTVRETL--------MFAAKLRGL----------------------------------------------------- 112
|
170 180 190
....*....|....*....|....*....|....*...
gi 1226689869 158 dmktgllSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD 195
Cdd:cd03213 113 -------SGGERKRVSIALELVSNPSLLFLDEPTSGLD 143
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
3-60 |
8.32e-09 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 57.02 E-value: 8.32e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 3 ILALQDVKKSF--GT---HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:COG1101 1 MLELKNLSKTFnpGTvneKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSI 63
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
329-393 |
9.16e-09 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 56.86 E-value: 9.16e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW----GTGVDL 393
Cdd:PRK11701 7 LSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYrmrdGQLRDL 75
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
333-538 |
1.03e-08 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 58.00 E-value: 1.03e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 333 GLSKGY-GDRILfRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQ-----------HQ 400
Cdd:PRK11288 9 GIGKTFpGVKAL-DDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILID-GQEMRFASTtaalaagvaiiYQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 401 sELH--ENKTVLDEVW-DRFP--------RMEQYEVRGAL-GLflftGDEV--FEPVSTLSGGEKGRVALTELMLRKDNV 466
Cdd:PRK11288 87 -ELHlvPEMTVAENLYlGQLPhkggivnrRLLNYEAREQLeHL----GVDIdpDTPLKYLSIGQRQMVEIAKALARNARV 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 467 LLLDEPTNHLdmDSRE-----ALENALSDFPGTIISVSHDRYFINRFAEKVWVL-DGneikEYLGNYDSYAlKVSRDQ 538
Cdd:PRK11288 162 IAFDEPTSSL--SAREieqlfRVIRELRAEGRVILYVSHRMEEIFALCDAITVFkDG----RYVATFDDMA-QVDRDQ 232
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
343-500 |
1.04e-08 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 56.13 E-value: 1.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 343 LFRDLKM----HVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW------------------------------- 387
Cdd:PRK10771 10 LYHHLPMrfdlTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLngqdhtttppsrrpvsmlfqennlfshltva 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 388 ---GTGVD----LGYYDQHQSELHENKTVLDEVWDRFPrmeqyevrgalglflftgdevfepvSTLSGGEKGRVALTELM 460
Cdd:PRK10771 90 qniGLGLNpglkLNAAQREKLHAIARQMGIEDLLARLP-------------------------GQLSGGQRQRVALARCL 144
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1226689869 461 LRKDNVLLLDEPTNHLDMDSREALENALSDFPG----TIISVSH 500
Cdd:PRK10771 145 VREQPILLLDEPFSALDPALRQEMLTLVSQVCQerqlTLLMVSH 188
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
3-97 |
1.13e-08 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 56.47 E-value: 1.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSmqkglrigYLAQQGELTgeet 82
Cdd:PRK11701 6 LLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVH--------YRMRDGQLR---- 73
|
90
....*....|....*
gi 1226689869 83 vleTLESVFEPQRRM 97
Cdd:PRK11701 74 ---DLYALSEAERRR 85
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
332-501 |
1.14e-08 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 57.04 E-value: 1.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW-GTGVD------LGY-------Y- 396
Cdd:COG4152 5 KGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWdGEPLDpedrrrIGYlpeerglYp 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 397 -----DQ-------HQSELHENKTVLDEVWDRFprmeqyevrgalGLflftGDEVFEPVSTLSGGEKGRVALTELMLRKD 464
Cdd:COG4152 85 kmkvgEQlvylarlKGLSKAEAKRRADEWLERL------------GL----GDRANKKVEELSKGNQQKVQLIAALLHDP 148
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1226689869 465 NVLLLDEPTNHLDMDSREALENALSDF--PG-TIISVSHD 501
Cdd:COG4152 149 ELLILDEPFSGLDPVNVELLKDVIRELaaKGtTVIFSSHQ 188
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
4-195 |
1.20e-08 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 55.58 E-value: 1.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTlqDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkGLRIGY----------LAQ 73
Cdd:cd03298 1 VRLDKIRFSYGEQPMHFDLTFA--QGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLIN-GVDVTAappadrpvsmLFQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 74 QGELTGEETVLETLESVFEPQRRMEAELRsleQEMAesgsdpEALRILGgkydtltrefersngygwrssvqgvLAGLEL 153
Cdd:cd03298 78 ENNLFAHLTVEQNVGLGLSPGLKLTAEDR---QAIE------VALARVG-------------------------LAGLEK 123
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1226689869 154 RefqdmKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD 195
Cdd:cd03298 124 R-----LPGELSGGERQRVALARVLVRDKPVLLLDEPFAALD 160
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
4-219 |
1.20e-08 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 56.19 E-value: 1.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEvLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ---------KGLRIGYLAQQ 74
Cdd:cd03299 1 LKVENLSKDWKEFK-LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNgkditnlppEKRDISYVPQN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 75 GELTGEETVLETLESVFEPQRRMEAELRSLEQEMAESgsdpealrilggkydtltrefersngygwrssvqgvlagLELR 154
Cdd:cd03299 80 YALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEM---------------------------------------LGID 120
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 155 EFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG----AVLVISHD 219
Cdd:cd03299 121 HLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKLREELKKIRKefgvTVLHVTHD 189
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
343-519 |
1.24e-08 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 55.55 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 343 LFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVdlGYYDQ---HQSE-LHENkTVLDEVWDrfp 418
Cdd:cd03250 20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGSI--AYVSQepwIQNGtIREN-ILFGKPFD--- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 419 rMEQYE--VRG-ALG--LFLFT-GD--EVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREAL-ENALS 489
Cdd:cd03250 94 -EERYEkvIKAcALEpdLEILPdGDltEIGEKGINLSGGQKQRISLARAVYSDADIYLLDDPLSAVDAHVGRHIfENCIL 172
|
170 180 190
....*....|....*....|....*....|...
gi 1226689869 490 DF---PGTIISVSHDRYFINRfAEKVWVLDGNE 519
Cdd:cd03250 173 GLllnNKTRILVTHQLQLLPH-ADQIVVLDNGR 204
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
345-522 |
1.37e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 56.71 E-value: 1.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 345 RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtgvDLGYY----DQH---------------QSELHE 405
Cdd:PRK13646 24 HDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVD---DITIThktkDKYirpvrkrigmvfqfpESQLFE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 N-------------KTVLDEVWDRfprmeQYEVRGALGlflFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEP 472
Cdd:PRK13646 101 DtvereiifgpknfKMNLDEVKNY-----AHRLLMDLG---FSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEP 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 473 TNHLDMDSREALENALSDFP----GTIISVSHDRYFINRFAEKVWVLDGNEIKE 522
Cdd:PRK13646 173 TAGLDPQSKRQVMRLLKSLQtdenKTIILVSHDMNEVARYADEVIVMKEGSIVS 226
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
2-60 |
1.40e-08 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 55.49 E-value: 1.40e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 2 IILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:PRK10247 6 PLLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTL 64
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
329-523 |
1.45e-08 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 58.00 E-value: 1.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGY--GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGV----IRWGT----------GV- 391
Cdd:TIGR01271 1218 MDVQGLTAKYteAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTEGEIqidgVSWNSvtlqtwrkafGVi 1297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 392 -------------DLGYYDQHQSElhENKTVLDEVWDRfPRMEQYEvrGALGLFLFTGDEVfepvstLSGGEKGRVALTE 458
Cdd:TIGR01271 1298 pqkvfifsgtfrkNLDPYEQWSDE--EIWKVAEEVGLK-SVIEQFP--DKLDFVLVDGGYV------LSNGHKQLMCLAR 1366
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 459 LMLRKDNVLLLDEPTNHLDMDS----REALENALSDFpgTIISVSHdRYFINRFAEKVWVLDGNEIKEY 523
Cdd:TIGR01271 1367 SILSKAKILLLDEPSAHLDPVTlqiiRKTLKQSFSNC--TVILSEH-RVEALLECQQFLVIEGSSVKQY 1432
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
328-520 |
1.61e-08 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 56.17 E-value: 1.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW-GTGVDLG------------ 394
Cdd:PRK13638 1 MLATSDLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWqGKPLDYSkrgllalrqqva 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 395 ----------YYDQHQSELHENKTVLDEVWDRFPRmeqyEVRGALGLflfTGDEVF--EPVSTLSGGEKGRVALTELMLR 462
Cdd:PRK13638 81 tvfqdpeqqiFYTDIDSDIAFSLRNLGVPEAEITR----RVDEALTL---VDAQHFrhQPIQCLSHGQKKRVAIAGALVL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 463 KDNVLLLDEPTNHLDMDSREALENALSDFPG----TIISvSHDRYFINRFAEKVWVLDGNEI 520
Cdd:PRK13638 154 QARYLLLDEPTAGLDPAGRTQMIAIIRRIVAqgnhVIIS-SHDIDLIYEISDAVYVLRQGQI 214
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
1-204 |
1.71e-08 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 55.69 E-value: 1.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAgletadsgtvsmqkglRIGYLAQQGELTGE 80
Cdd:PRK14247 1 MNKIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFN----------------RLIELYPEARVSGE 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 81 etVLETLESVFepqrRME-AELRSLEQEMAESGSDPEALRI-----LGGKYDTLTRE----FERSngygwRSSVQGVLAG 150
Cdd:PRK14247 65 --VYLDGQDIF----KMDvIELRRRVQMVFQIPNPIPNLSIfenvaLGLKLNRLVKSkkelQERV-----RWALEKAQLW 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 151 LELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEE 204
Cdd:PRK14247 134 DEVKDRLDAPAGKLSGGQQQRLCIARALAFQPEVLLADEPTANLDPENTAKIES 187
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
16-200 |
1.83e-08 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 56.04 E-value: 1.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 16 HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM-----QKGLR---IGYLAQQGELTGEETVLetL 87
Cdd:PRK15056 20 HTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISIlgqptRQALQknlVAYVPQSEEVDWSFPVL--V 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 88 ESVfepqrrmeaelrsleqemaesgsdpealrILGGKYDT---LTREFERSngygwRSSVQGVLAGLELREFQDMKTGLL 164
Cdd:PRK15056 98 EDV-----------------------------VMMGRYGHmgwLRRAKKRD-----RQIVTAALARVDMVEFRHRQIGEL 143
|
170 180 190
....*....|....*....|....*....|....*.
gi 1226689869 165 SGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIA 200
Cdd:PRK15056 144 SGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEA 179
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
342-523 |
1.87e-08 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 57.65 E-value: 1.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 342 ILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW-GTGV-DLGYYDqhqseLHENKTVL--DEVW--- 414
Cdd:TIGR00957 1300 LVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIdGLNIaKIGLHD-----LRFKITIIpqDPVLfsg 1374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 415 ------DRFPRMEQYEVRGALGLFLFTG----------DEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDM 478
Cdd:TIGR00957 1375 slrmnlDPFSQYSDEEVWWALELAHLKTfvsalpdkldHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDL 1454
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1226689869 479 DSREALENAL-SDFPG-TIISVSHDRYFINRFAeKVWVLDGNEIKEY 523
Cdd:TIGR00957 1455 ETDNLIQSTIrTQFEDcTVLTIAHRLNTIMDYT-RVIVLDKGEVAEF 1500
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
3-60 |
2.04e-08 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 56.28 E-value: 2.04e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 3 ILALQDVKKSF--------GTHEVLKSV---SFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:COG4608 7 LLEVRDLKKHFpvrgglfgRTVGVVKAVdgvSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEI 75
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
341-520 |
2.32e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 55.91 E-value: 2.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 341 RILFrDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGV--------DLGYYDQH--------QSELH 404
Cdd:PRK13649 21 RALF-DVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLitstsknkDIKQIRKKvglvfqfpESQLF 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 405 EnKTVLDEVW---DRFPRMEQYEVRGALGLFLFTG--DEVFE--PVStLSGGEKGRVALTELMLRKDNVLLLDEPTNHLD 477
Cdd:PRK13649 100 E-ETVLKDVAfgpQNFGVSQEEAEALAREKLALVGisESLFEknPFE-LSGGQMRRVAIAGILAMEPKILVLDEPTAGLD 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1226689869 478 MDSREALenaLSDFPG------TIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:PRK13649 178 PKGRKEL---MTLFKKlhqsgmTIVLVTHLMDDVANYADFVYVLEKGKL 223
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
4-104 |
2.35e-08 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 55.38 E-value: 2.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSF-GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkG----------LR--IGY 70
Cdd:cd03295 1 IEFENVTKRYgGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFID-GedireqdpveLRrkIGY 79
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1226689869 71 LAQQGELTGEETVLE------TLESVFEPQRRMEA-ELRSL 104
Cdd:cd03295 80 VIQQIGLFPHMTVEEnialvpKLLKWPKEKIRERAdELLAL 120
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
23-218 |
2.39e-08 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 54.42 E-value: 2.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 23 SFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkGLRIG-----------YLAQQ----GELTGEETvletl 87
Cdd:PRK13538 21 SFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQ-GEPIRrqrdeyhqdllYLGHQpgikTELTALEN----- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 88 esvfepqrrmeaeLRSLEQemaesgsdpealriLGGKYDtltrefersngygwRSSVQGVLAGLELREFQDMKTGLLSGG 167
Cdd:PRK13538 95 -------------LRFYQR--------------LHGPGD--------------DEALWEALAQVGLAGFEDVPVRQLSAG 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 168 ERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAfH----GAVLVISH 218
Cdd:PRK13538 134 QQRRVALARLWLTRAPLWILDEPFTAIDKQGVARLEALLAQ-HaeqgGMVILTTH 187
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
3-52 |
2.44e-08 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 56.21 E-value: 2.44e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 3 ILALQDVKKSFGTHE----VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGL 52
Cdd:COG0444 1 LLEVRNLKVYFPTRRgvvkAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGL 54
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
1-229 |
2.52e-08 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 55.28 E-value: 2.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM-----------QKGLR-I 68
Cdd:PRK10895 1 MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIddedisllplhARARRgI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 69 GYLAQQGELTGEETVLETLESVFEPQRRMEAELRsleQEMAESgsdpealrilggkydtLTREFERSNgygwrssvqgvl 148
Cdd:PRK10895 81 GYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQR---EDRANE----------------LMEEFHIEH------------ 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 149 aglelreFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDE------PTNHLDLKSIAwleEYLAAFHGAVLVISHD-RY 221
Cdd:PRK10895 130 -------LRDSMGQSLSGGERRRVEIARALAANPKFILLDEpfagvdPISVIDIKRII---EHLRDSGLGVLITDHNvRE 199
|
....*...
gi 1226689869 222 FLDrVCGR 229
Cdd:PRK10895 200 TLA-VCER 206
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
8-195 |
2.75e-08 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 54.97 E-value: 2.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 8 DVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETAD---SGTV----------SMQKglRIGYLAQQ 74
Cdd:cd03234 12 KAKNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGgttSGQIlfngqprkpdQFQK--CVAYVRQD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 75 GELTGEETVLETLesVFEPQRRMEAELRSLE-QEMAESGSDPE-ALRILGGKYdtltrefersngygwrssVQGvlagle 152
Cdd:cd03234 90 DILLPGLTVRETL--TYTAILRLPRKSSDAIrKKRVEDVLLRDlALTRIGGNL------------------VKG------ 143
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1226689869 153 lrefqdmktglLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD 195
Cdd:cd03234 144 -----------ISGGERRRVSIAVQLLWDPKVLILDEPTSGLD 175
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
19-219 |
2.87e-08 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 54.94 E-value: 2.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLeTADSGTVS-MQKGL----------RIGYLAQQGELTGEETVLETL 87
Cdd:PRK03695 12 LGPLSAEVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQfAGQPLeawsaaelarHRAYLSQQQTPPFAMPVFQYL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 88 eSVFEPQRRMEAELRSLEQEMAesgsdpEALRILggkyDTLTRefersngygwrsSVQGvlaglelrefqdmktglLSGG 167
Cdd:PRK03695 91 -TLHQPDKTRTEAVASALNEVA------EALGLD----DKLGR------------SVNQ-----------------LSGG 130
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 168 E--RTRL---CL---------GRMlltepdlLLLDEPTNHLDLKSIAWLEEYLAAF---HGAVLVISHD 219
Cdd:PRK03695 131 EwqRVRLaavVLqvwpdinpaGQL-------LLLDEPMNSLDVAQQAALDRLLSELcqqGIAVVMSSHD 192
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
339-522 |
2.89e-08 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 54.72 E-value: 2.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 339 GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLG-----YYDQHQSELHENKTVL-DE 412
Cdd:PRK10247 18 GDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLF-EGEDIStlkpeIYRQQVSYCAQTPTLFgDT 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 413 VWDR--FPrmeqYEVRG--------ALGLFLFTGDEVF--EPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDS 480
Cdd:PRK10247 97 VYDNliFP----WQIRNqqpdpaifLDDLERFALPDTIltKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESN 172
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1226689869 481 R----EALENALSDFPGTIISVSHDRYFINRfAEKVWVLD--GNEIKE 522
Cdd:PRK10247 173 KhnvnEIIHRYVREQNIAVLWVTHDKDEINH-ADKVITLQphAGEMQE 219
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
326-473 |
2.93e-08 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 56.57 E-value: 2.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 326 DDVLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW-GTGV---------DLGY 395
Cdd:COG1129 2 EPLLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLdGEPVrfrsprdaqAAGI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 396 YDQHQsELH--ENKTVLDEVW-DRFPR---------MEQyEVRGALGLFLFTGDeVFEPVSTLSGGEKGRVALTELMLRK 463
Cdd:COG1129 82 AIIHQ-ELNlvPNLSVAENIFlGREPRrgglidwraMRR-RARELLARLGLDID-PDTPVGDLSVAQQQLVEIARALSRD 158
|
170
....*....|
gi 1226689869 464 DNVLLLDEPT 473
Cdd:COG1129 159 ARVLILDEPT 168
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
329-482 |
3.04e-08 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 54.41 E-value: 3.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDA---GVIrWGTGVDLGYYDQHQSEL-- 403
Cdd:COG4136 2 LSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAFsasGEV-LLNGRRLTALPAEQRRIgi 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 404 ---------HENktvldeVWD--------RFPRME-QYEVRGAL---GLflftGDEVFEPVSTLSGGEKGRVALTELMLR 462
Cdd:COG4136 81 lfqddllfpHLS------VGEnlafalppTIGRAQrRARVEQALeeaGL----AGFADRDPATLSGGQRARVALLRALLA 150
|
170 180
....*....|....*....|
gi 1226689869 463 KDNVLLLDEPTNHLDMDSRE 482
Cdd:COG4136 151 EPRALLLDEPFSKLDAALRA 170
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
329-488 |
3.04e-08 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 55.09 E-value: 3.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW------GTGVDLGYYDQHQSe 402
Cdd:PRK11248 2 LQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLdgkpveGPGAERGVVFQNEG- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 403 LHENKTVLDEV-----WDRFPRMEQYEVrgALGLFLFTGDEVFE--PVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNH 475
Cdd:PRK11248 81 LLPWRNVQDNVafglqLAGVEKMQRLEI--AHQMLKKVGLEGAEkrYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGA 158
|
170
....*....|...
gi 1226689869 476 LDMDSREALENAL 488
Cdd:PRK11248 159 LDAFTREQMQTLL 171
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
341-521 |
3.11e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 55.41 E-value: 3.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 341 RILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGV--------DLGYYDQH--------QSELH 404
Cdd:PRK13634 20 RRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVitagkknkKLKPLRKKvgivfqfpEHQLF 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 405 EnKTVLDEVwdRFPRM------EQYEVRGALGLFLFTGDEV------FEpvstLSGGEKGRVALTELMLRKDNVLLLDEP 472
Cdd:PRK13634 100 E-ETVEKDI--CFGPMnfgvseEDAKQKAREMIELVGLPEEllarspFE----LSGGQMRRVAIAGVLAMEPEVLVLDEP 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 473 TNHLD-------MDSREAL--ENALsdfpgTIISVSHDRYFINRFAEKVWVLDGNEIK 521
Cdd:PRK13634 173 TAGLDpkgrkemMEMFYKLhkEKGL-----TTVLVTHSMEDAARYADQIVVMHKGTVF 225
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
345-528 |
4.73e-08 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 56.12 E-value: 4.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 345 RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGyyDQHQSELHEN-KTVLDE--VWDRF---- 417
Cdd:PRK13657 352 EDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILI-DGTDIR--TVTRASLRRNiAVVFQDagLFNRSiedn 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 418 -----PRMEQYEVRGALGL-----FLFTGDEVFEPV-----STLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSRE 482
Cdd:PRK13657 429 irvgrPDATDEEMRAAAERaqahdFIERKPDGYDTVvgergRQLSGGERQRLAIARALLKDPPILILDEATSALDVETEA 508
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 483 ALENALSDfpgtiisVSHDR-YFI-------NRFAEKVWVLDGNEIKEyLGNYD 528
Cdd:PRK13657 509 KVKAALDE-------LMKGRtTFIiahrlstVRNADRILVFDNGRVVE-SGSFD 554
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
4-239 |
5.13e-08 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 54.59 E-value: 5.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQQGEL-TGEET 82
Cdd:PRK10619 6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKDGQLkVADKN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 VLETLES----VFEpQRRMEAELRSLEQEMaesgsdpEA-LRILGgkydtLTREFERSNGYGWRSSVqgvlaGLELREfQ 157
Cdd:PRK10619 86 QLRLLRTrltmVFQ-HFNLWSHMTVLENVM-------EApIQVLG-----LSKQEARERAVKYLAKV-----GIDERA-Q 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 158 DMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD---LKSIAWLEEYLAAFHGAVLVISHDRYFLDRVCGRMAELL 234
Cdd:PRK10619 147 GKYPVHLSGGQQQRVSIARALAMEPEVLLFDEPTSALDpelVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLH 226
|
....*
gi 1226689869 235 LGNVE 239
Cdd:PRK10619 227 QGKIE 231
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
3-219 |
5.40e-08 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 55.89 E-value: 5.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSF----GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmqkglrigYLAQQGELT 78
Cdd:PRK10535 4 LLELKDIRRSYpsgeEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTY---------RVAGQDVAT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 79 GEETVLETLESV---FEPQRrmeaeLRSLEQEMAESGSDPEALrilggkYDTLTREfERsngygwRSSVQGVLAGLELRE 155
Cdd:PRK10535 75 LDADALAQLRREhfgFIFQR-----YHLLSHLTAAQNVEVPAV------YAGLERK-QR------LLRAQELLQRLGLED 136
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 156 FQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSiawLEEYLAAFHG------AVLVISHD 219
Cdd:PRK10535 137 RVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHS---GEEVMAILHQlrdrghTVIIVTHD 203
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
358-521 |
5.76e-08 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 55.27 E-value: 5.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 358 ALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVdlgYYDQHQSE-LHENKTVLDEVWD--R-FPrmeQYEVRGAL---- 429
Cdd:PRK11144 28 AIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRV---LFDAEKGIcLPPEKRRIGYVFQdaRlFP---HYKVRGNLrygm 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 430 -----GLFlftgDEV-----FEPV-----STLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMD-SREA---LENALSD 490
Cdd:PRK11144 102 aksmvAQF----DKIvallgIEPLldrypGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPrKRELlpyLERLARE 177
|
170 180 190
....*....|....*....|....*....|.
gi 1226689869 491 FPGTIISVSHDRYFINRFAEKVWVLDGNEIK 521
Cdd:PRK11144 178 INIPILYVSHSLDEILRLADRVVVLEQGKVK 208
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-195 |
7.69e-08 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 53.99 E-value: 7.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-------------SMQKGL- 66
Cdd:PRK11264 1 MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIrvgditidtarslSQQKGLi 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 67 -----RIGYLAQQGELTGEETVLETL---ESVFEPQRRMEAELRSLEQeMAESGsdpealriLGGKYDTLTREfersngy 138
Cdd:PRK11264 81 rqlrqHVGFVFQNFNLFPHRTVLENIiegPVIVKGEPKEEATARAREL-LAKVG--------LAGKETSYPRR------- 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 139 gwrssvqgvlaglelrefqdmktglLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD 195
Cdd:PRK11264 145 -------------------------LSGGQQQRVAIARALAMRPEVILFDEPTSALD 176
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
6-61 |
7.89e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 54.23 E-value: 7.89e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 6 LQDVKKSFGTHE--VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVS 61
Cdd:PRK13632 10 VENVSFSYPNSEnnALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIK 67
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
354-522 |
8.95e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 54.32 E-value: 8.95e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 354 GDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtgvdlgYYDQH-QSELHENKTVLDEVWDRFPRMEQY----EVRGA 428
Cdd:PRK13651 33 GEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWI------FKDEKnKKKTKEKEKVLEKLVIQKTRFKKIkkikEIRRR 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 429 LG-LFLFTGDEVFE----------PVS-------------------------------TLSGGEKGRVALTELMLRKDNV 466
Cdd:PRK13651 107 VGvVFQFAEYQLFEqtiekdiifgPVSmgvskeeakkraakyielvgldesylqrspfELSGGQKRRVALAGILAMEPDF 186
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 467 LLLDEPTNHLD-MDSREALE--NALSDFPGTIISVSHDRYFINRFAEKVWVL-DGNEIKE 522
Cdd:PRK13651 187 LVFDEPTAGLDpQGVKEILEifDNLNKQGKTIILVTHDLDNVLEWTKRTIFFkDGKIIKD 246
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
4-219 |
9.74e-08 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 53.53 E-value: 9.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmqkglrigylaqqgeLTGEetv 83
Cdd:PRK11247 13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGEL----------------LAGT--- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 84 lETLESVFEPQRRM--EAELRSLEQEMAESGsdpealriLGGKYDtltrefersngygWRSSVQGVLAGLELREFQDMKT 161
Cdd:PRK11247 74 -APLAEAREDTRLMfqDARLLPWKKVIDNVG--------LGLKGQ-------------WRDAALQALAAVGLADRANEWP 131
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 162 GLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD-LKSIAW--LEEYLAAFHG-AVLVISHD 219
Cdd:PRK11247 132 AALSGGQKQRVALARALIHRPGLLLLDEPLGALDaLTRIEMqdLIESLWQQHGfTVLLVTHD 193
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
3-52 |
9.97e-08 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 54.94 E-value: 9.97e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGL 52
Cdd:PRK13549 5 LLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGV 54
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
4-63 |
1.02e-07 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 53.22 E-value: 1.02e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHevLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ 63
Cdd:COG3840 2 LRLDDLTYRYGDF--PLRFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWN 59
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
7-218 |
1.28e-07 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 54.73 E-value: 1.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 7 QDVKKSFGTH---EVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkGLRIG-----YLAQQGELT 78
Cdd:TIGR00958 482 QDVSFSYPNRpdvPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLD-GVPLVqydhhYLHRQVALV 560
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 79 GEETVLETlesvfepqrrmeaelRSLEQEMAESGSDPEALRILGGKYDTLTREF--ERSNGYgwrssvqgvlaGLELREf 156
Cdd:TIGR00958 561 GQEPVLFS---------------GSVRENIAYGLTDTPDEEIMAAAKAANAHDFimEFPNGY-----------DTEVGE- 613
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 157 qdmKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHGAVLVISH 218
Cdd:TIGR00958 614 ---KGSQLSGGQKQRIAIARALVRKPRVLILDEATSALDAECEQLLQESRSRASRTVLLIAH 672
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
14-195 |
1.53e-07 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 54.28 E-value: 1.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 14 GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETAD---SGTVsMQKGLRI---------GYLAQQGELTGEE 81
Cdd:TIGR00955 36 PRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSV-LLNGMPIdakemraisAYVQQDDLFIPTL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 82 TVLETLesVFEPQRRMEAELRSLEQemaesgsdpealrilggkydtltrefersngygwRSSVQGVLAGLELREFQDMKT 161
Cdd:TIGR00955 115 TVREHL--MFQAHLRMPRRVTKKEK----------------------------------RERVDEVLQALGLRKCANTRI 158
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1226689869 162 GL------LSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD 195
Cdd:TIGR00955 159 GVpgrvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGLD 198
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
3-196 |
1.61e-07 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 53.09 E-value: 1.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMqKGLRIGYLAQQgELTGEET 82
Cdd:PRK11231 2 TLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFL-GDKPISMLSSR-QLARRLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 VLetlesvfePQRRMEAELRSLeQEMAESGSDPealrilggkYDTLTREFERSNgygwRSSVQGVLAGLELREFQDMKTG 162
Cdd:PRK11231 80 LL--------PQHHLTPEGITV-RELVAYGRSP---------WLSLWGRLSAED----NARVNQAMEQTRINHLADRRLT 137
|
170 180 190
....*....|....*....|....*....|....
gi 1226689869 163 LLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDL 196
Cdd:PRK11231 138 DLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDI 171
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
328-517 |
1.84e-07 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 52.51 E-value: 1.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDRIL----FRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAG-VIRWGTGV----------- 391
Cdd:PRK11629 5 LLQCDNLCKRYQEGSVqtdvLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGdVIFNGQPMsklssaakael 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 392 ---DLGY-YDQHQseLHENKTVLDEV------WDRFPRMEQ---YEVRGALGLflftGDEVFEPVSTLSGGEKGRVALTE 458
Cdd:PRK11629 85 rnqKLGFiYQFHH--LLPDFTALENVamplliGKKKPAEINsraLEMLAAVGL----EHRANHRPSELSGGERQRVAIAR 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 459 LMLRKDNVLLLDEPTNHLDM---DSREALENALSDFPGT-IISVSHDRYFINRFAEKVWVLDG 517
Cdd:PRK11629 159 ALVNNPRLVLADEPTGNLDArnaDSIFQLLGELNRLQGTaFLVVTHDLQLAKRMSRQLEMRDG 221
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
4-196 |
1.87e-07 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 54.36 E-value: 1.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFG-THEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM---------QKGLR--IGYL 71
Cdd:TIGR01193 474 IVINDVSYSYGyGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLngfslkdidRHTLRqfINYL 553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 72 AQQGEL-TGeeTVLETLESVFEPQRRMEAELRSLEqeMAESGSDPEALrilggkydtltreferSNGYGWRSSVQGvlag 150
Cdd:TIGR01193 554 PQEPYIfSG--SILENLLLGAKENVSQDEIWAACE--IAEIKDDIENM----------------PLGYQTELSEEG---- 609
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1226689869 151 lelrefqdmktGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDL 196
Cdd:TIGR01193 610 -----------SSISGGQKQRIALARALLTDSKVLILDESTSNLDT 644
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
2-51 |
1.97e-07 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 52.72 E-value: 1.97e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1226689869 2 IILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAG 51
Cdd:CHL00131 6 PILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG 55
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
1-58 |
1.99e-07 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 53.49 E-value: 1.99e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSG 58
Cdd:PRK11000 1 MASVTLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSG 58
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
328-473 |
2.25e-07 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 52.19 E-value: 2.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYdQHQSELHENK 407
Cdd:PRK11614 5 MLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFD-GKDITDW-QTAKIMREAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 408 TVLDEVWDRFPRM---------------EQYEVRGA--LGLFLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLD 470
Cdd:PRK11614 83 AIVPEGRRVFSRMtveenlamggffaerDQFQERIKwvYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLD 162
|
...
gi 1226689869 471 EPT 473
Cdd:PRK11614 163 EPS 165
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
18-60 |
2.66e-07 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 52.43 E-value: 2.66e-07
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1226689869 18 VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:TIGR04520 17 ALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKV 59
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
22-88 |
3.58e-07 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 53.59 E-value: 3.58e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 22 VSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV----------SMQKGLRIGYLAQQGELTGEETVLETLE 88
Cdd:NF033858 285 VSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAwlfgqpvdagDIATRRRVGYMSQAFSLYGELTVRQNLE 361
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
445-516 |
3.85e-07 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 53.49 E-value: 3.85e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 445 TLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPG----TIISVSHDRYFINRfAEKVWVLD 516
Cdd:PTZ00265 1358 SLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDkadkTIITIAHRIASIKR-SDKIVVFN 1432
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
18-225 |
3.90e-07 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 51.10 E-value: 3.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 18 VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLetadsgtvsmqkglrigYLAQQGELTgeetvletlesvFEPQRrM 97
Cdd:PRK13540 16 LLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGL-----------------LNPEKGEIL------------FERQS-I 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 98 EAELRSLEQEMA----ESGSDPealrilggkYDTLtrefeRSNGYGWRSSVQGVLAGLEL-REFQ-----DMKTGLLSGG 167
Cdd:PRK13540 66 KKDLCTYQKQLCfvghRSGINP---------YLTL-----RENCLYDIHFSPGAVGITELcRLFSlehliDYPCGLLSSG 131
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 168 ERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSI----AWLEEYLAAfHGAVLVISHDRYFLDR 225
Cdd:PRK13540 132 QKRQVALLRLWMSKAKLWLLDEPLVALDELSLltiiTKIQEHRAK-GGAVLLTSHQDLPLNK 192
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
19-60 |
3.97e-07 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 51.94 E-value: 3.97e-07
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:PRK13635 23 LKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTI 64
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
16-88 |
4.14e-07 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 52.97 E-value: 4.14e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 16 HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIgyLAQQGELTGEETVLETLE 88
Cdd:PRK13545 37 HYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSAAL--IAISSGLNGQLTGIENIE 107
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
345-520 |
4.21e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 51.92 E-value: 4.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 345 RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRwgtgVDLGYYDQHQSELHENK---------------TV 409
Cdd:PRK13632 26 KNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIK----IDGITISKENLKEIRKKigiifqnpdnqfigaTV 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 410 LDEVW-----DRFPRMEQ----YEVRGALGL--FLftgdeVFEPVStLSGGEKGRVALTELMLRKDNVLLLDEPTNHLD- 477
Cdd:PRK13632 102 EDDIAfglenKKVPPKKMkdiiDDLAKKVGMedYL-----DKEPQN-LSGGQKQRVAIASVLALNPEIIIFDESTSMLDp 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1226689869 478 ---MDSREALENALSDFPGTIISVSHD-RYFINrfAEKVWVLDGNEI 520
Cdd:PRK13632 176 kgkREIKKIMVDLRKTRKKTLISITHDmDEAIL--ADKVIVFSEGKL 220
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
328-477 |
4.35e-07 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 51.43 E-value: 4.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVI--------------RWGTGVdl 393
Cdd:PRK10895 3 TLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIiiddedisllplhaRARRGI-- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 394 GYYDQHQS-----ELHENKTVLDEVWDRFPRmEQYEVRGALGLFLFTGDEVFEPV-STLSGGEKGRVALTELMLRKDNVL 467
Cdd:PRK10895 81 GYLPQEASifrrlSVYDNLMAVLQIRDDLSA-EQREDRANELMEEFHIEHLRDSMgQSLSGGERRRVEIARALAANPKFI 159
|
170
....*....|
gi 1226689869 468 LLDEPTNHLD 477
Cdd:PRK10895 160 LLDEPFAGVD 169
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
354-505 |
4.37e-07 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 49.68 E-value: 4.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 354 GDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVDLGYYDQHQSELHenktvldevwdrfprmeqyevrgalglfl 433
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLI----------------------------- 52
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 434 ftgdEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPGTIISVSHDRYFI 505
Cdd:smart00382 53 ----IVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEELRLLLLLKSEKNLTVI 120
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
3-194 |
4.52e-07 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 52.70 E-value: 4.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTvsmqkglrIGYLAQQGELTGeet 82
Cdd:PRK10762 4 LLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGS--------ILYLGKEVTFNG--- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 vletlesvfePQRRMEAELRSLEQEMAESGSDPEALRILggkydtLTREFerSNGYG---WR---SSVQGVLAGLELREF 156
Cdd:PRK10762 73 ----------PKSSQEAGIGIIHQELNLIPQLTIAENIF------LGREF--VNRFGridWKkmyAEADKLLARLNLRFS 134
|
170 180 190
....*....|....*....|....*....|....*...
gi 1226689869 157 QDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHL 194
Cdd:PRK10762 135 SDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEPTDAL 172
|
|
| sufC |
TIGR01978 |
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ... |
4-224 |
4.54e-07 |
|
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]
Pssm-ID: 273907 [Multi-domain] Cd Length: 243 Bit Score: 51.49 E-value: 4.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLET--ADSGTVSMQ--------------KGLr 67
Cdd:TIGR01978 1 LKIKDLHVSVEDKEILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAGHPSyeVTSGTILFKgqdllelepderarAGL- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 68 igYLAQQG--ELTGEeTVLETLESVFEPQRRMEAElrsleqemaESGSDPEALRILGGKYDTLTREFERSNgygwRSsvq 145
Cdd:TIGR01978 80 --FLAFQYpeEIPGV-SNLEFLRSALNARRSARGE---------EPLDLLDFEKLLKEKLALLDMDEEFLN----RS--- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 146 gvlaglelrefqdMKTGLlSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD---LKSIAWLEEYLAAFHGAVLVISHDRYF 222
Cdd:TIGR01978 141 -------------VNEGF-SGGEKKRNEILQMALLEPKLAILDEIDSGLDidaLKIVAEGINRLREPDRSFLIITHYQRL 206
|
..
gi 1226689869 223 LD 224
Cdd:TIGR01978 207 LN 208
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
340-477 |
4.58e-07 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 51.12 E-value: 4.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 340 DRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIG-VEKPDA--GVIrWGTGVDL---------GYYDQHQSeLHENK 407
Cdd:cd03234 19 YARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGrVEGGGTtsGQI-LFNGQPRkpdqfqkcvAYVRQDDI-LLPGL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 408 TVlDEVWD-----RFPRM---EQYEVRGALGLFLFTGDEVF--EPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLD 477
Cdd:cd03234 97 TV-RETLTytailRLPRKssdAIRKKRVEDVLLRDLALTRIggNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLD 175
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
3-238 |
4.91e-07 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 51.71 E-value: 4.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmqkglrigyLAQQGELTGEET 82
Cdd:PRK10575 11 TFALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEI----------LLDAQPLESWSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 VLETLESVFEPQRRMEAELRSLeQEMAESGSDP--EALrilgGKYDTLTREfersngygwrsSVQGVLAGLELREFQDMK 160
Cdd:PRK10575 81 KAFARKVAYLPQQLPAAEGMTV-RELVAIGRYPwhGAL----GRFGAADRE-----------KVEEAISLVGLKPLAHRL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 161 TGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDlksIAWLEEYLAAFHG-------AVLVISHDRYFLDRVCGRMAEL 233
Cdd:PRK10575 145 VDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALD---IAHQVDVLALVHRlsqerglTVIAVLHDINMAARYCDYLVAL 221
|
....*
gi 1226689869 234 LLGNV 238
Cdd:PRK10575 222 RGGEM 226
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
345-527 |
5.29e-07 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 52.71 E-value: 5.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 345 RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYDQhqSELHE------------NKTVLDE 412
Cdd:PRK11176 360 RNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILL-DGHDLRDYTL--ASLRNqvalvsqnvhlfNDTIANN 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 413 VwdRFPRMEQY---EVRGALGL-----FLFTGDEVFEPV-----STLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMD 479
Cdd:PRK11176 437 I--AYARTEQYsreQIEEAARMayamdFINKMDNGLDTVigengVLLSGGQRQRIAIARALLRDSPILILDEATSALDTE 514
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1226689869 480 SREALENALSDFPG--TIISVSHDRYFINRfAEKVWVLDGNEIKEYlGNY 527
Cdd:PRK11176 515 SERAIQAALDELQKnrTSLVIAHRLSTIEK-ADEILVVEDGEIVER-GTH 562
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
2-60 |
5.68e-07 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 50.12 E-value: 5.68e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 2 IILALQDVkksfGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:cd03215 3 PVLEVRGL----SVKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEI 57
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
19-219 |
6.12e-07 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 50.99 E-value: 6.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLeTADSGTVSMQkGLRI------------GYLAQQGELTGEETVLET 86
Cdd:COG4138 12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGL-LPGQGEILLN-GRPLsdwsaaelarhrAYLSQQQSPPFAMPVFQY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 87 LeSVFEPQRRMEAELRSLEQEMAesgsdpEALRILggkyDTLTREFERsngygwrssvqgvlaglelrefqdmktglLSG 166
Cdd:COG4138 90 L-ALHQPAGASSEAVEQLLAQLA------EALGLE----DKLSRPLTQ-----------------------------LSG 129
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 167 GE--RTRL---CL---------GRMlltepdlLLLDEPTNHLDlksIA-------WLEEyLAAFHGAVLVISHD 219
Cdd:COG4138 130 GEwqRVRLaavLLqvwptinpeGQL-------LLLDEPMNSLD---VAqqaaldrLLRE-LCQQGITVVMSSHD 192
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
332-477 |
7.61e-07 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 51.62 E-value: 7.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGY----GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYD---------- 397
Cdd:COG1135 5 ENLSKTFptkgGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVD-GVDLTALSerelraarrk 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 398 -----QHqSELHENKTVLD------EVWdRFPRMEQYE-VrgalglflftgDEVFEPV----------STLSGGEKGRV- 454
Cdd:COG1135 84 igmifQH-FNLLSSRTVAEnvalplEIA-GVPKAEIRKrV-----------AELLELVglsdkadaypSQLSGGQKQRVg 150
|
170 180
....*....|....*....|....*....
gi 1226689869 455 ---ALTelmlrkdN---VLLLDEPTNHLD 477
Cdd:COG1135 151 iarALA-------NnpkVLLCDEATSALD 172
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
332-520 |
7.74e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 51.14 E-value: 7.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRI-LFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAG--VIRwgtGVDLGYYdqhqSELHENKT 408
Cdd:PRK13644 5 ENVSYSYPDGTpALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGkvLVS---GIDTGDF----SKLQGIRK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 409 VLDEVWDRfPRME--------------------QYEVRGALGLFLF-TGDEVFEPVS--TLSGGEKGRVALTELMLRKDN 465
Cdd:PRK13644 78 LVGIVFQN-PETQfvgrtveedlafgpenlclpPIEIRKRVDRALAeIGLEKYRHRSpkTLSGGQGQCVALAGILTMEPE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 466 VLLLDEPTNHLDMDSREA-LENA--LSDFPGTIISVSHDRYFINRfAEKVWVLDGNEI 520
Cdd:PRK13644 157 CLIFDEVTSMLDPDSGIAvLERIkkLHEKGKTIVYITHNLEELHD-ADRIIVMDRGKI 213
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
3-242 |
8.03e-07 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 50.93 E-value: 8.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAgletadsgtvsmqkglRIGYLAQQGELTGeeT 82
Cdd:PRK14239 5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSIN----------------RMNDLNPEVTITG--S 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 VLETLESVFEPqRRMEAELRSlEQEMAESGSDP----------EALRILGGK-YDTLTREFERSngygwrssVQGVLAGL 151
Cdd:PRK14239 67 IVYNGHNIYSP-RTDTVDLRK-EIGMVFQQPNPfpmsiyenvvYGLRLKGIKdKQVLDEAVEKS--------LKGASIWD 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 152 ELRE-FQDMKTGLlSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAFHG--AVLVISHDRYFLDRVCG 228
Cdd:PRK14239 137 EVKDrLHDSALGL-SGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDdyTMLLVTRSMQQASRISD 215
|
250
....*....|....
gi 1226689869 229 RMAELLLGNVETYS 242
Cdd:PRK14239 216 RTGFFLDGDLIEYN 229
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
13-196 |
8.23e-07 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 50.76 E-value: 8.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 13 FGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV-----------SMQKGLRIGYLAQQGELTGEE 81
Cdd:PRK10253 17 YGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVwldgehiqhyaSKEVARRIGLLAQNATTPGDI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 82 TVletlesvfepqrrmeaelrsleQEMAESGSDPEAlrilggkyDTLTRefersngygWR----SSVQGVLAGLELREFQ 157
Cdd:PRK10253 97 TV----------------------QELVARGRYPHQ--------PLFTR---------WRkedeEAVTKAMQATGITHLA 137
|
170 180 190
....*....|....*....|....*....|....*....
gi 1226689869 158 DMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDL 196
Cdd:PRK10253 138 DQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDI 176
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
18-74 |
8.61e-07 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 49.07 E-value: 8.61e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 18 VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQQ 74
Cdd:cd03223 16 LLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMPEGEDLLFLPQR 72
|
|
| PCRF |
pfam03462 |
PCRF domain; This domain is found in peptide chain release factors. |
584-634 |
1.04e-06 |
|
PCRF domain; This domain is found in peptide chain release factors.
Pssm-ID: 460929 [Multi-domain] Cd Length: 192 Bit Score: 49.69 E-value: 1.04e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 584 EKEAGEMEAELADPEIWKDPDKAAETTRRYNALKDEIERlYEQYDALESSL 634
Cdd:pfam03462 2 EERYEELEALLSDPDVWDDQKRAQKLSKEYSELEPIVEA-YREYKQALEDL 51
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
17-198 |
1.20e-06 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 50.18 E-value: 1.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 17 EVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsMQKGLRIG-----YLAQQGELTGEETVLETlesvf 91
Cdd:cd03252 16 VILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRV-LVDGHDLAladpaWLRRQVGVVLQENVLFN----- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 92 epqrrmeaelRSLEQEMAESGSDPEALRI-----LGGKYDTLTrefERSNGYGWRSSVQGVlaglelrefqdmktgLLSG 166
Cdd:cd03252 90 ----------RSIRDNIALADPGMSMERVieaakLAGAHDFIS---ELPEGYDTIVGEQGA---------------GLSG 141
|
170 180 190
....*....|....*....|....*....|..
gi 1226689869 167 GERTRLCLGRMLLTEPDLLLLDEPTNHLDLKS 198
Cdd:cd03252 142 GQRQRIAIARALIHNPRILIFDEATSALDYES 173
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
4-73 |
1.20e-06 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 49.92 E-value: 1.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTH-EVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM---------QKGLR--IGYL 71
Cdd:cd03253 1 IEFENVTFAYDPGrPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIdgqdirevtLDSLRraIGVV 80
|
..
gi 1226689869 72 AQ 73
Cdd:cd03253 81 PQ 82
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
10-238 |
1.31e-06 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 51.24 E-value: 1.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 10 KKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTimkiiAGLETadsgtvsmqkgLRIgyLAQQGELTGEETVLETL-- 87
Cdd:PRK15134 293 KRTVDHNVVVKNISFTLRPGETLGLVGESGSGKST-----TGLAL-----------LRL--INSQGEIWFDGQPLHNLnr 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 88 ----------ESVFE-PQRRMEAELrSLEQEMAesgsdpEALRIlggKYDTLTREfERSngygwrssvQGVLAGLElref 156
Cdd:PRK15134 355 rqllpvrhriQVVFQdPNSSLNPRL-NVLQIIE------EGLRV---HQPTLSAA-QRE---------QQVIAVME---- 410
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 157 qdmKTGL-----------LSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD---LKSIAWLEEYLAAFHG-AVLVISHDRY 221
Cdd:PRK15134 411 ---EVGLdpetrhrypaeFSGGQRQRIAIARALILKPSLIILDEPTSSLDktvQAQILALLKSLQQKHQlAYLFISHDLH 487
|
250
....*....|....*..
gi 1226689869 222 FLDRVCGRMAELLLGNV 238
Cdd:PRK15134 488 VVRALCHQVIVLRQGEV 504
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
4-61 |
1.37e-06 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 51.07 E-value: 1.37e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVS 61
Cdd:PRK11288 5 LSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSIL 62
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
4-241 |
1.54e-06 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 49.33 E-value: 1.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTH--EVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkGLRIGYLaqqgeltgee 81
Cdd:cd03369 7 IEVENLSVRYAPDlpPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEID-GIDISTI---------- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 82 tvletlesvfepqrrmeaELRSLEQEMAESGSDPEalrILGGkydTLTREFERSNGYgwrSSVQgVLAGLELREfqdmkT 161
Cdd:cd03369 76 ------------------PLEDLRSSLTIIPQDPT---LFSG---TIRSNLDPFDEY---SDEE-IYGALRVSE-----G 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 162 GL-LSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYL-AAFHGA-VLVISHD-RYFLDrvCGRMAELLLGN 237
Cdd:cd03369 123 GLnLSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTIrEEFTNStILTIAHRlRTIID--YDKILVMDAGE 200
|
....
gi 1226689869 238 VETY 241
Cdd:cd03369 201 VKEY 204
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
328-523 |
1.61e-06 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 49.77 E-value: 1.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCL--IGVEKPDAGVirwgTG--------------- 390
Cdd:PRK14239 5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNDLNPEVTI----TGsivynghniysprtd 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 391 -VDL----GYYDQHQS----ELHEN------------KTVLDE----------VWDrfprmeqyEVRgalglflftgDEV 439
Cdd:PRK14239 81 tVDLrkeiGMVFQQPNpfpmSIYENvvyglrlkgikdKQVLDEavekslkgasIWD--------EVK----------DRL 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 440 FEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPG--TIISVSHDRYFINRFAEKV-WVLD 516
Cdd:PRK14239 143 HDSALGLSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDdyTMLLVTRSMQQASRISDRTgFFLD 222
|
....*..
gi 1226689869 517 GNEIkEY 523
Cdd:PRK14239 223 GDLI-EY 228
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
4-60 |
1.72e-06 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 50.49 E-value: 1.72e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:PRK11432 7 VVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQI 63
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
4-60 |
2.07e-06 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 48.46 E-value: 2.07e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 4 LALQDVKKSFGTHE--VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:cd03247 1 LSINNVSFSYPEQEqqVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEI 59
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
332-488 |
2.34e-06 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 50.49 E-value: 2.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGY-GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgTGVDLGYYD-----QHQSELHE 405
Cdd:PRK10790 344 DNVSFAYrDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRL-DGRPLSSLShsvlrQGVAMVQQ 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 NKTVL----------------DEVWDRFPRMEQYEVRGAL--GLFLFTGdevfEPVSTLSGGEKGRVALTELMLRKDNVL 467
Cdd:PRK10790 423 DPVVLadtflanvtlgrdiseEQVWQALETVQLAELARSLpdGLYTPLG----EQGNNLSVGQKQLLALARVLVQTPQIL 498
|
170 180
....*....|....*....|.
gi 1226689869 468 LLDEPTNHLDMDSREALENAL 488
Cdd:PRK10790 499 ILDEATANIDSGTEQAIQQAL 519
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
345-515 |
2.70e-06 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 49.35 E-value: 2.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 345 RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWgtgvdLGyydqhqSELHENKtvldevwdrfprmeQYE 424
Cdd:PRK13647 22 KGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKV-----MG------REVNAEN--------------EKW 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 425 VRGALGLFL------------------------FTGDEVFEPVST-----------------LSGGEKGRVALTELMLRK 463
Cdd:PRK13647 77 VRSKVGLVFqdpddqvfsstvwddvafgpvnmgLDKDEVERRVEEalkavrmwdfrdkppyhLSYGQKKRVAIAGVLAMD 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 464 DNVLLLDEPTNHLDMDSREALENALSDFPG---TIISVSHDRYFINRFAEKVWVL 515
Cdd:PRK13647 157 PDVIVLDEPMAYLDPRGQETLMEILDRLHNqgkTVIVATHDVDLAAEWADQVIVL 211
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
3-52 |
3.99e-06 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 49.82 E-value: 3.99e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGL 52
Cdd:TIGR02633 1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGV 50
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
335-485 |
4.07e-06 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 48.03 E-value: 4.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 335 SKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGvekpdagvirwgtgvDLGYYDQHQSELHENKTVLDEVW 414
Cdd:cd03233 14 GKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALAN---------------RTEGNVSVEGDIHYNGIPYKEFA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 415 DRFPRMEQYEVRGALGLFLFT------------GDEVfepVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSre 482
Cdd:cd03233 79 EKYPGEIIYVSEEDVHFPTLTvretldfalrckGNEF---VRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSST-- 153
|
...
gi 1226689869 483 ALE 485
Cdd:cd03233 154 ALE 156
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
18-226 |
4.61e-06 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 49.75 E-value: 4.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 18 VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM-----------QKGLRIGYLAQQGELtgeetvlet 86
Cdd:COG4618 347 ILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLdgadlsqwdreELGRHIGYLPQDVEL--------- 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 87 LE-SVFEPQRRMEaelrsleqemaesGSDPEA--------------LRILGGkYDTLTREfersNGYGwrssvqgvlagl 151
Cdd:COG4618 418 FDgTIAENIARFG-------------DADPEKvvaaaklagvhemiLRLPDG-YDTRIGE----GGAR------------ 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 152 elrefqdmktglLSGGERTRLCLGR----------MlltepdllllDEPTNHLDLKSIAWLEEYLAAF--HGA-VLVISH 218
Cdd:COG4618 468 ------------LSGGQRQRIGLARalygdprlvvL----------DEPNSNLDDEGEAALAAAIRALkaRGAtVVVITH 525
|
....*...
gi 1226689869 219 DRYFLDRV 226
Cdd:COG4618 526 RPSLLAAV 533
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
14-218 |
4.64e-06 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 47.99 E-value: 4.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 14 GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM---------QKGLR--IGYLAQqgeltgeET 82
Cdd:cd03254 14 EKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIdgidirdisRKSLRsmIGVVLQ-------DT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 VLETlESVFEPQR--RMEAELRSLEQEMAESGSDPEALRILGGkYDTLTREfersNGygwrssvqgvlaglelrefqdmk 160
Cdd:cd03254 87 FLFS-GTIMENIRlgRPNATDEEVIEAAKEAGAHDFIMKLPNG-YDTVLGE----NG----------------------- 137
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 161 tGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAA-FHG-AVLVISH 218
Cdd:cd03254 138 -GNLSQGERQLLAIARAMLRDPKILILDEATSNIDTETEKLIQEALEKlMKGrTSIIIAH 196
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1-60 |
4.81e-06 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 49.03 E-value: 4.81e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 1 MIilALQDVKKSF----GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:PRK11153 1 MI--ELKNISKVFpqggRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRV 62
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
11-62 |
5.82e-06 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 49.25 E-value: 5.82e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 11 KSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM 62
Cdd:COG1129 260 EGLSVGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRL 311
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
19-219 |
6.57e-06 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 47.85 E-value: 6.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkglrigylAQQGELTGEETVLetlesVFepQRRME 98
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILE--------GKQITEPGPDRMV-----VF--QNYSL 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 99 AELRSLEQEMAESGSdpEALRILggkydtltREFERsngygwRSSVQGVLAGLELREFQDMKTGLLSGGERTRLCLGRML 178
Cdd:TIGR01184 66 LPWLTVRENIALAVD--RVLPDL--------SKSER------RAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARAL 129
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1226689869 179 LTEPDLLLLDEPTNHLDLKSIAWLEEYLAAF----HGAVLVISHD 219
Cdd:TIGR01184 130 SIRPKVLLLDEPFGALDALTRGNLQEELMQIweehRVTVLMVTHD 174
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
16-74 |
6.74e-06 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 49.04 E-value: 6.74e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 16 HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQQ 74
Cdd:COG4178 376 RPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARPAGARVLFLPQR 434
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
342-500 |
6.86e-06 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 49.36 E-value: 6.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 342 ILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGTGVDLGYYDQH----QSELHENKTVLDEVWDRF 417
Cdd:TIGR00954 466 VLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKPAKGKLFYVPQRpymtLGTLRDQIIYPDSSEDMK 545
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 418 PR------MEQYEVRGALGLFLFTG---DEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENAL 488
Cdd:TIGR00954 546 RRglsdkdLEQILDNVQLTHILEREggwSAVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGYMYRLC 625
|
170
....*....|..
gi 1226689869 489 SDFPGTIISVSH 500
Cdd:TIGR00954 626 REFGITLFSVSH 637
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
442-507 |
6.88e-06 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 46.93 E-value: 6.88e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 442 PVSTLSGGEKGRVALT-ELMLRKDNVL-LLDEPTNHLDMDSREALENA---LSDFPGTIISVSHDRYFINR 507
Cdd:cd03238 84 KLSTLSGGELQRVKLAsELFSEPPGTLfILDEPSTGLHQQDINQLLEVikgLIDLGNTVILIEHNLDVLSS 154
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
4-51 |
7.56e-06 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 47.14 E-value: 7.56e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAG 51
Cdd:cd03217 1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMG 48
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
17-60 |
8.88e-06 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 47.86 E-value: 8.88e-06
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1226689869 17 EVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:PRK15112 27 EAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGEL 70
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
25-230 |
9.44e-06 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 47.40 E-value: 9.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 25 TLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkGLRIGYLAQQGELTGEETVLETLESVfepqrrmeaelrsl 104
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIE-LDTVSYKPQYIKADYEGTVRDLLSSI-------------- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 105 eqeMAESGSDPEalrilggkydtltrefersngygWRSSVqgvLAGLELREFQDMKTGLLSGGERTR----LCLGRmllt 180
Cdd:cd03237 86 ---TKDFYTHPY-----------------------FKTEI---AKPLQIEQILDREVPELSGGELQRvaiaACLSK---- 132
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 181 EPDLLLLDEPTNHLDL-------KSIAWLEEYLAAfhgAVLVISHDRYFLDRVCGRM 230
Cdd:cd03237 133 DADIYLLDEPSAYLDVeqrlmasKVIRRFAENNEK---TAFVVEHDIIMIDYLADRL 186
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
4-60 |
9.79e-06 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 47.37 E-value: 9.79e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLE--TADSGTV 60
Cdd:COG0396 1 LEIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPkyEVTSGSI 59
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
351-501 |
1.06e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 47.78 E-value: 1.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 351 VRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIR-----------WGTGVDLGYYDQHQSELHENKTVLDEVW----- 414
Cdd:PRK13642 30 ITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKidgelltaenvWNLRRKIGMVFQNPDNQFVGATVEDDVAfgmen 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 415 DRFPRMEQYE-VRGALGLFLFTGDEVFEPvSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPG 493
Cdd:PRK13642 110 QGIPREEMIKrVDEALLAVNMLDFKTREP-ARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKE 188
|
170
....*....|..
gi 1226689869 494 ----TIISVSHD 501
Cdd:PRK13642 189 kyqlTVLSITHD 200
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
333-523 |
1.20e-05 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 46.93 E-value: 1.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 333 GLSKGYG-DRILFrDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtgvdlGYYDQHQSELHENK---- 407
Cdd:COG4161 7 NINCFYGsHQALF-DINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIA-----GHQFDFSQKPSEKAirll 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 408 -----------------TVLD---EVWDRFPRMEQYEVRG-ALGLF----LFTGDEVFePVStLSGGEKGRVALTELMLR 462
Cdd:COG4161 81 rqkvgmvfqqynlwphlTVMEnliEAPCKVLGLSKEQAREkAMKLLarlrLTDKADRF-PLH-LSGGQQQRVAIARALMM 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 463 KDNVLLLDEPTNHLDMDSREALENALSDFPGTIIS---VSHDRYFINRFAEKVWVLDGNEIKEY 523
Cdd:COG4161 159 EPQVLLFDEPTAALDPEITAQVVEIIRELSQTGITqviVTHEVEFARKVASQVVYMEKGRIIEQ 222
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
19-60 |
1.23e-05 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 47.44 E-value: 1.23e-05
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:PRK13648 25 LKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEI 66
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
332-488 |
1.24e-05 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 48.28 E-value: 1.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGY-GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDQHqsELHE----- 405
Cdd:COG5265 361 ENVSFGYdPERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILID-GQDIRDVTQA--SLRAaigiv 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 -NKTVL------------------DEVW--------DRFPRM--EQYEVR-GALGLflftgdevfepvsTLSGGEKGRVA 455
Cdd:COG5265 438 pQDTVLfndtiayniaygrpdaseEEVEaaaraaqiHDFIESlpDGYDTRvGERGL-------------KLSGGEKQRVA 504
|
170 180 190
....*....|....*....|....*....|...
gi 1226689869 456 LTELMLRKDNVLLLDEPTNHLDMDSREALENAL 488
Cdd:COG5265 505 IARTLLKNPPILIFDEATSALDSRTERAIQAAL 537
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
19-88 |
1.32e-05 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 47.12 E-value: 1.32e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmQKGLRIGYLAQQGELTGEETVLETLE 88
Cdd:PRK13546 40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKV--DRNGEVSVIAISAGLSGQLTGIENIE 107
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
333-501 |
1.34e-05 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 47.07 E-value: 1.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 333 GLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIrWGTGvdlgyydqhqselhENKTVLDe 412
Cdd:PRK11831 12 GVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEI-LFDG--------------ENIPAMS- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 413 vwdrfpRMEQYEVRGALG-LF----LFTGDEVFEPV------------------------------------STLSGGEK 451
Cdd:PRK11831 76 ------RSRLYTVRKRMSmLFqsgaLFTDMNVFDNVayplrehtqlpapllhstvmmkleavglrgaaklmpSELSGGMA 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 452 GRVALTELMLRKDNVLLLDEP---TNHLDMDSREALENALSDFPG-TIISVSHD 501
Cdd:PRK11831 150 RRAALARAIALEPDLIMFDEPfvgQDPITMGVLVKLISELNSALGvTCVVVSHD 203
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
341-545 |
1.43e-05 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 47.13 E-value: 1.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 341 RILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGvEKPDAGVIRWGT--------GVDLGYYDQHQseLHENKTVL-- 410
Cdd:PRK13547 14 RAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAG-DLTGGGAPRGARvtgdvtlnGEPLAAIDAPR--LARLRAVLpq 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 411 ----------DEV--WDRFPrmeqyEVRGALGLFLFTGDEVFEP-------------VSTLSGGEKGRV----ALTELML 461
Cdd:PRK13547 91 aaqpafafsaREIvlLGRYP-----HARRAGALTHRDGEIAWQAlalagatalvgrdVTTLSGGELARVqfarVLAQLWP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 462 RKDNV-----LLLDEPTNHLDMDSREALENAL----SDFPGTIISVSHDRYFINRFAEKVWVLDGNEIKEYLGNYD---- 528
Cdd:PRK13547 166 PHDAAqppryLLLDEPTAALDLAHQHRLLDTVrrlaRDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADvltp 245
|
250 260
....*....|....*....|..
gi 1226689869 529 -----SYALKVSRDQEPDGSAP 545
Cdd:PRK13547 246 ahiarCYGFAVRLVDAGDGVPP 267
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
22-61 |
1.51e-05 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 47.87 E-value: 1.51e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1226689869 22 VSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVS 61
Cdd:COG4615 351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEIL 390
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
345-522 |
1.53e-05 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 47.49 E-value: 1.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 345 RDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtGVDLGYYDqhQSEL------------HEN----KT 408
Cdd:PRK11153 22 NNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVD-GQDLTALS--EKELrkarrqigmifqHFNllssRT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 409 VLDEVwdrfprmeqyevrgALGLFLfTG----------DEVFEPV----------STLSGGEKGRVALTELMLRKDNVLL 468
Cdd:PRK11153 99 VFDNV--------------ALPLEL-AGtpkaeikarvTELLELVglsdkadrypAQLSGGQKQRVAIARALASNPKVLL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 469 LDEPTNHLDMDSREALENALSD----FPGTIISVSHDRYFINRFAEKVWVLDGNEIKE 522
Cdd:PRK11153 164 CDEATSALDPATTRSILELLKDinreLGLTIVLITHEMDVVKRICDRVAVIDAGRLVE 221
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
2-63 |
1.58e-05 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 47.76 E-value: 1.58e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 2 IILALQDVKKSF-----------GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETAdSGTVSMQ 63
Cdd:COG4172 274 PLLEARDLKVWFpikrglfrrtvGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIPS-EGEIRFD 345
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
326-501 |
1.90e-05 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 46.70 E-value: 1.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 326 DDVLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQC------LIGVEKPDAGVIRWGTGVdlgyYDQH 399
Cdd:PRK14243 8 ETVLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCfnrlndLIPGFRVEGKVTFHGKNL----YAPD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 400 --------------------QSELHEN----------KTVLDEVWDRFPRMEQY--EVRgalglflftgDEVFEPVSTLS 447
Cdd:PRK14243 84 vdpvevrrrigmvfqkpnpfPKSIYDNiaygaringyKGDMDELVERSLRQAALwdEVK----------DKLKQSGLSLS 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 448 GGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPG--TIISVSHD 501
Cdd:PRK14243 154 GGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEqyTIIIVTHN 209
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
19-149 |
1.95e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 46.96 E-value: 1.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM------QKGL-------RIGYLAQQGELT-GEETVL 84
Cdd:PRK13637 23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIdgvditDKKVklsdirkKVGLVFQYPEYQlFEETIE 102
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 85 ETLEsvFEPQRRMEAelrslEQEMAESGSdpEALRILGGKYDTLTRE--FERSNGYGWRSSVQGVLA 149
Cdd:PRK13637 103 KDIA--FGPINLGLS-----EEEIENRVK--RAMNIVGLDYEDYKDKspFELSGGQKRRVAIAGVVA 160
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-191 |
1.97e-05 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 46.41 E-value: 1.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMqkglrigylaQQGELTGE 80
Cdd:PRK11614 3 KVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVF----------DGKDITDW 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 81 ETVLETLESV-FEPQRRMEAELRSLEQEMAesgsdpealriLGGKYDTLTREFERSngygwrSSVQGVLAGLELREFQdm 159
Cdd:PRK11614 73 QTAKIMREAVaIVPEGRRVFSRMTVEENLA-----------MGGFFAERDQFQERI------KWVYELFPRLHERRIQ-- 133
|
170 180 190
....*....|....*....|....*....|..
gi 1226689869 160 KTGLLSGGERTRLCLGRMLLTEPDLLLLDEPT 191
Cdd:PRK11614 134 RAGTMSGGEQQMLAIGRALMSQPRLLLLDEPS 165
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
357-486 |
2.00e-05 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 46.02 E-value: 2.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 357 IALI-GDNGTGKSTLLQCLIGVEKPDAGVIRWGT----GVDLGY--YDQHQSELHENKTVLDEV--WDRFPRMEQyEVRG 427
Cdd:PRK13541 28 ITYIkGANGCGKSSLLRMIAGIMQPSSGNIYYKNcninNIAKPYctYIGHNLGLKLEMTVFENLkfWSEIYNSAE-TLYA 106
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 428 ALGLFLFTgDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALEN 486
Cdd:PRK13541 107 AIHYFKLH-DLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDLLNN 164
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
10-74 |
2.09e-05 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 45.92 E-value: 2.09e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 10 KKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKglRIGYLAQQ 74
Cdd:cd03250 12 SGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG--SIAYVSQE 74
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
16-238 |
2.10e-05 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 46.74 E-value: 2.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 16 HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTvsmqKGLRIgylaqQGELTGEETVLETLesvfePQR 95
Cdd:PRK13547 14 RAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGGAP----RGARV-----TGDVTLNGEPLAAI-----DAP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 96 RMeAELRSLEQEMAESGSDPEALRI-LGGKYDTLTREFE---RSNGYGWRSSvqgVLAGLELREFQDMKTglLSGGERTR 171
Cdd:PRK13547 80 RL-ARLRAVLPQAAQPAFAFSAREIvLLGRYPHARRAGAlthRDGEIAWQAL---ALAGATALVGRDVTT--LSGGELAR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 172 LCLGRM---------LLTEPDLLLLDEPTNHLDLKSIAWLEEYLAA----FHGAVLVISHDRYFLDRVCGRMAELLLGNV 238
Cdd:PRK13547 154 VQFARVlaqlwpphdAAQPPRYLLLDEPTAALDLAHQHRLLDTVRRlardWNLGVLAIVHDPNLAARHADRIAMLADGAI 233
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
15-60 |
2.12e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 46.65 E-value: 2.12e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1226689869 15 THEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:PRK13650 19 EKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQI 64
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-43 |
2.39e-05 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 47.37 E-value: 2.39e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1226689869 1 MIILALQDVKKSFGT----HEVLKSVSFTLQDGERMGLVGVNGSGKS 43
Cdd:COG4172 4 MPLLSVEDLSVAFGQgggtVEAVKGVSFDIAAGETLALVGESGSGKS 50
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
3-51 |
2.71e-05 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 47.09 E-value: 2.71e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAG 51
Cdd:NF040905 1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSG 49
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
19-149 |
2.86e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 46.28 E-value: 2.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV----------SMQKGLR-----IGYLAQQGE-LTGEET 82
Cdd:PRK13649 23 LFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVrvddtlitstSKNKDIKqirkkVGLVFQFPEsQLFEET 102
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 83 VLETLesVFEPQR----RMEAELRSLEQemaesgsdpeaLRILGGKYDTLTRE-FERSNGYGWRSSVQGVLA 149
Cdd:PRK13649 103 VLKDV--AFGPQNfgvsQEEAEALAREK-----------LALVGISESLFEKNpFELSGGQMRRVAIAGILA 161
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
19-219 |
2.92e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 46.36 E-value: 2.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM----------QKGL-----RIGYLAQQGELT-GEET 82
Cdd:PRK13641 23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIagyhitpetgNKNLkklrkKVSLVFQFPEAQlFENT 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 VLETLEsvFEPQRRMEAELRSLEQEMaesgsdpEALRILGGKYDTLTRE-FERSNGYGWRSSVQGVLAglelrefqdmkt 161
Cdd:PRK13641 103 VLKDVE--FGPKNFGFSEDEAKEKAL-------KWLKKVGLSEDLISKSpFELSGGQMRRVAIAGVMA------------ 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 162 gllsgGERTRLCLgrmlltepdllllDEPTNHLDLKS----IAWLEEYLAAFHgAVLVISHD 219
Cdd:PRK13641 162 -----YEPEILCL-------------DEPAAGLDPEGrkemMQLFKDYQKAGH-TVILVTHN 204
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
444-519 |
3.65e-05 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 46.95 E-value: 3.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 444 STLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPG-----TIIsVSHdRYFINRFAEKVWVLDGN 518
Cdd:PTZ00265 578 SKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGnenriTII-IAH-RLSTIRYANTIFVLSNR 655
|
.
gi 1226689869 519 E 519
Cdd:PTZ00265 656 E 656
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
346-419 |
4.25e-05 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 46.65 E-value: 4.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 346 DLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW-GTGVDL---------GYYDQHQsELHE--NKTVLDEV 413
Cdd:PRK10982 16 NVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFqGKEIDFksskealenGISMVHQ-ELNLvlQRSVMDNM 94
|
....*..
gi 1226689869 414 W-DRFPR 419
Cdd:PRK10982 95 WlGRYPT 101
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
334-519 |
4.26e-05 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 45.80 E-value: 4.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 334 LSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRWGT-----------GVDLGYYDQHQSE 402
Cdd:PRK14258 13 LSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESEVRVEGRveffnqniyerRVNLNRLRRQVSM 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 403 LHENK-----TVLDEV--------WDrfPRMEQYE-VRGALG---LFLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDN 465
Cdd:PRK14258 93 VHPKPnlfpmSVYDNVaygvkivgWR--PKLEIDDiVESALKdadLWDEIKHKIHKSALDLSGGQQQRLCIARALAVKPK 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 466 VLLLDEPTNHLD----MDSREALENALSDFPGTIISVSHDRYFINRFAEKVWVLDGNE 519
Cdd:PRK14258 171 VLLMDEPCFGLDpiasMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGNE 228
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
18-195 |
5.02e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 45.56 E-value: 5.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 18 VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSmqkglRIGYLaqqGELTGEETVLETLESV---FE-P 93
Cdd:PRK13640 22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPNS-----KITVD---GITLTAKTVWDIREKVgivFQnP 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 94 QRRMEAElrSLEQEMA-----ESGSDPEALRIlggkydtltrefersngygwrssVQGVLAGLELREFQDMKTGLLSGGE 168
Cdd:PRK13640 94 DNQFVGA--TVGDDVAfglenRAVPRPEMIKI-----------------------VRDVLADVGMLDYIDSEPANLSGGQ 148
|
170 180
....*....|....*....|....*..
gi 1226689869 169 RTRLCLGRMLLTEPDLLLLDEPTNHLD 195
Cdd:PRK13640 149 KQRVAIAGILAVEPKIIILDESTSMLD 175
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
15-238 |
5.58e-05 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 46.39 E-value: 5.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 15 THEV--LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkGLRIGYLAqqgeltgeetvletlESVFE 92
Cdd:PRK10261 334 TREVhaVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFN-GQRIDTLS---------------PGKLQ 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 93 PQRR-----MEAELRSLEQEMAESGSDPEALRILGgkydtLTREFERSNGYGWRSSVQGVLAGLELR---EFqdmktgll 164
Cdd:PRK10261 398 ALRRdiqfiFQDPYASLDPRQTVGDSIMEPLRVHG-----LLPGKAAAARVAWLLERVGLLPEHAWRyphEF-------- 464
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 165 SGGERTRLCLGRMLLTEPDLLLLDEPTNHLDL----KSIAWLEEYLAAFHGAVLVISHDRYFLDRVCGRMAELLLGNV 238
Cdd:PRK10261 465 SGGQRQRICIARALALNPKVIIADEAVSALDVsirgQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQI 542
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
16-49 |
5.91e-05 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 44.84 E-value: 5.91e-05
10 20 30
....*....|....*....|....*....|....
gi 1226689869 16 HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKII 49
Cdd:cd03249 16 VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLL 49
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
332-522 |
7.07e-05 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 44.62 E-value: 7.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYG-DRILFrDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAG---------------------VIRWGT 389
Cdd:PRK11124 6 NGINCFYGaHQALF-DITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGtlniagnhfdfsktpsdkairELRRNV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 390 GVDLGYYD--QHQSELH---------------ENKTVLDEVWDRFpRMEQYEVRGALglflftgdevfepvsTLSGGEKG 452
Cdd:PRK11124 85 GMVFQQYNlwPHLTVQQnlieapcrvlglskdQALARAEKLLERL-RLKPYADRFPL---------------HLSGGQQQ 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 453 RVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPGTIIS---VSHDRYFINRFAEKVWVLDGNEIKE 522
Cdd:PRK11124 149 RVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETGITqviVTHEVEVARKTASRVVYMENGHIVE 221
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
359-515 |
7.89e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 45.00 E-value: 7.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 359 LIGDNGTGKSTLLQ------------CLIGVEKPDAGV--------IRWGTGVDLGY--YDQHQS-----------ELHE 405
Cdd:PRK13645 42 VIGTTGSGKSTMIQltngliisetgqTIVGDYAIPANLkkikevkrLRKEIGLVFQFpeYQLFQEtiekdiafgpvNLGE 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 406 NKtvlDEVWDRFPRMeqyevrgaLGLFLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALE 485
Cdd:PRK13645 122 NK---QEAYKKVPEL--------LKLVQLPEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFI 190
|
170 180 190
....*....|....*....|....*....|....
gi 1226689869 486 NAL----SDFPGTIISVSHDRYFINRFAEKVWVL 515
Cdd:PRK13645 191 NLFerlnKEYKKRIIMVTHNMDQVLRIADEVIVM 224
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
23-59 |
8.48e-05 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 44.57 E-value: 8.48e-05
10 20 30
....*....|....*....|....*....|....*..
gi 1226689869 23 SFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGT 59
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGS 55
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
4-60 |
9.65e-05 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 44.14 E-value: 9.65e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 4 LALQDVKKSFGTHE--VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:cd03251 1 VEFKNVTFRYPGDGppVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRI 59
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
18-46 |
1.04e-04 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 44.02 E-value: 1.04e-04
10 20
....*....|....*....|....*....
gi 1226689869 18 VLKSVSFTLQDGERMGLVGVNGSGKSTIM 46
Cdd:cd03244 19 VLKNISFSIKPGEKVGIVGRTGSGKSSLL 47
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
2-61 |
1.21e-04 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 44.70 E-value: 1.21e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 2 IILALQDVKKSFG-------------THEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVS 61
Cdd:PRK15079 7 VLLEVADLKVHFDikdgkqwfwqppkTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVA 79
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
329-386 |
1.27e-04 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 44.21 E-value: 1.27e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 329 LMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIR 386
Cdd:PRK11300 6 LSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTIL 63
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
4-268 |
1.27e-04 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 45.20 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVkkSFG----THEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAgletadsgtvsmqkglRiGYLAQQGELT- 78
Cdd:PRK11160 339 LTLNNV--SFTypdqPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLT----------------R-AWDPQQGEILl 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 79 -GE------ETVLETLESVFePQR--RMEAELRSLEQEMAESGSDpEALRilggkydtltrefersngygwrssvqGVLA 149
Cdd:PRK11160 400 nGQpiadysEAALRQAISVV-SQRvhLFSATLRDNLLLAAPNASD-EALI--------------------------EVLQ 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 150 GLELREFQDMKTGL----------LSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKS----IAWLEEYLAafHGAVLV 215
Cdd:PRK11160 452 QVGLEKLLEDDKGLnawlgeggrqLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETerqiLELLAEHAQ--NKTVLM 529
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 216 ISHDRYFL---DRVC----GRMAElllgnvetySGNYTEYLEKRTtvyenrmRAWKLQQK 268
Cdd:PRK11160 530 ITHRLTGLeqfDRICvmdnGQIIE---------QGTHQELLAQQG-------RYYQLKQR 573
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
15-231 |
1.36e-04 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 43.92 E-value: 1.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 15 THEVL-KSVSFTLQDGERMGLVGVNGSGKStiMKIIAGLETADSGTVSMQKGLRI-GYLAQQGELTGEE--TVLETLESV 90
Cdd:PRK10418 14 AAQPLvHGVSLTLQRGRVLALVGGSGSGKS--LTCAAALGILPAGVRQTAGRVLLdGKPVAPCALRGRKiaTIMQNPRSA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 91 FEPQRRMEAELRSLEQEMAESGSDPEALRILggkydtltrefeRSNGYGWRSSVqgvlagLELREFQdmktglLSGGERT 170
Cdd:PRK10418 92 FNPLHTMHTHARETCLALGKPADDATLTAAL------------EAVGLENAARV------LKLYPFE------MSGGMLQ 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 171 RLCLGRMLLTEPDLLLLDEPTNHLDLKS---IAWLEEYLAAFHG-AVLVISHDRYFLDRVCGRMA 231
Cdd:PRK10418 148 RMMIALALLCEAPFIIADEPTTDLDVVAqarILDLLESIVQKRAlGMLLVTHDMGVVARLADDVA 212
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
351-387 |
1.39e-04 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 44.99 E-value: 1.39e-04
10 20 30
....*....|....*....|....*....|....*..
gi 1226689869 351 VRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRW 387
Cdd:PRK10762 27 VYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILY 63
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
331-500 |
1.54e-04 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 43.68 E-value: 1.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 331 TEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQC---LIGVeKPDA---GVIRWgTGVDLGYYDQHQSELH 404
Cdd:PRK14267 7 TVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTfnrLLEL-NEEArveGEVRL-FGRNIYSPDVDPIEVR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 405 ENKTVLDEVWDRFPRMEQYEvRGALGL----FLFTGDEVFEPV---------------------STLSGGEKGRVALTEL 459
Cdd:PRK14267 85 REVGMVFQYPNPFPHLTIYD-NVAIGVklngLVKSKKELDERVewalkkaalwdevkdrlndypSNLSGGQRQRLVIARA 163
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1226689869 460 MLRKDNVLLLDEPTNHLDMDSREALENALSDFPG--TIISVSH 500
Cdd:PRK14267 164 LAMKPKILLMDEPTANIDPVGTAKIEELLFELKKeyTIVLVTH 206
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
3-219 |
1.63e-04 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 43.84 E-value: 1.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkGLRIGYlAQQGELTGEET 82
Cdd:PRK13638 1 MLATSDLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQ-GKPLDY-SKRGLLALRQQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 VletlESVFEPQrrmeaelrslEQEMAESGSDPE---ALRILGGKYDTLTREfersngygwrssVQGVLAGLELREFQDM 159
Cdd:PRK13638 79 V----ATVFQDP----------EQQIFYTDIDSDiafSLRNLGVPEAEITRR------------VDEALTLVDAQHFRHQ 132
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 160 KTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD----LKSIAWLEEyLAAFHGAVLVISHD 219
Cdd:PRK13638 133 PIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDpagrTQMIAIIRR-IVAQGNHVIISSHD 195
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
332-537 |
1.63e-04 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 44.78 E-value: 1.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIRwgtgVDLGYYDQHQSEL-------- 403
Cdd:PRK09700 9 AGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTIT----INNINYNKLDHKLaaqlgigi 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 404 -HENKTVLDE----------------VWD------RFPRMEQYEVRGALGLFLftgdEVFEPVSTLSGGEKGRVALTELM 460
Cdd:PRK09700 85 iYQELSVIDEltvlenlyigrhltkkVCGvniidwREMRVRAAMMLLRVGLKV----DLDEKVANLSISHKQMLEIAKTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 461 LRKDNVLLLDEPTNHL---DMDSREALENALSDFPGTIISVSHDRYFINRFAEKVWVL-DGN-----EIKEyLGNYDSYA 531
Cdd:PRK09700 161 MLDAKVIIMDEPTSSLtnkEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMkDGSsvcsgMVSD-VSNDDIVR 239
|
....*.
gi 1226689869 532 LKVSRD 537
Cdd:PRK09700 240 LMVGRE 245
|
|
| COG3950 |
COG3950 |
Predicted ATP-binding protein involved in virulence [General function prediction only]; |
19-119 |
1.68e-04 |
|
Predicted ATP-binding protein involved in virulence [General function prediction only];
Pssm-ID: 443150 [Multi-domain] Cd Length: 276 Bit Score: 43.83 E-value: 1.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 19 LKSVSFTLQDGERMG-LVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIgyLAQQGELTGEETVLetleSVFEPQRRM 97
Cdd:COG3950 14 FEDLEIDFDNPPRLTvLVGENGSGKTTLLEAIALALSGLLSRLDDVKFRKL--LIRNGEFGDSAKLI----LYYGTSRLL 87
|
90 100
....*....|....*....|...
gi 1226689869 98 -EAELRSLEQEMAESGSDPEALR 119
Cdd:COG3950 88 lDGPLKKLERLKEEYFSRLDGYD 110
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
19-219 |
1.72e-04 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 43.93 E-value: 1.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmqkglrigylaqqgELTGEETvleTLESVFEPQRRME 98
Cdd:PRK13642 23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKV---------------KIDGELL---TAENVWNLRRKIG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 99 AELRSLEQEMAesGSDPEALRILGGKYDTLTREfersngyGWRSSVQGVLAGLELREFQDMKTGLLSGGERTRLCLGRML 178
Cdd:PRK13642 85 MVFQNPDNQFV--GATVEDDVAFGMENQGIPRE-------EMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGII 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1226689869 179 LTEPDLLLLDEPTNHLDLKS----IAWLEEYLAAFHGAVLVISHD 219
Cdd:PRK13642 156 ALRPEIIILDESTSMLDPTGrqeiMRVIHEIKEKYQLTVLSITHD 200
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
357-501 |
1.74e-04 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 43.08 E-value: 1.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 357 IALIGDNGTGKSTLLQCL--------IGVEKPDAGVIRWGTG-------------------------------------- 390
Cdd:COG0419 26 NLIVGPNGAGKSTILEAIryalygkaRSRSKLRSDLINVGSEeasvelefehggkryrierrqgefaefleakpserkea 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 391 ----VDLGYYDQHQSELHENKTVLDEVWDRFPRMEQYEVRgalglfLFTGDEVFEPVSTLSGGEKGRVALTELMlrkdnV 466
Cdd:COG0419 106 lkrlLGLEIYEELKERLKELEEALESALEELAELQKLKQE------ILAQLSGLDPIETLSGGERLRLALADLL-----S 174
|
170 180 190
....*....|....*....|....*....|....*
gi 1226689869 467 LLLDepTNHLDMDSREALENALSDfpgtIISVSHD 501
Cdd:COG0419 175 LILD--FGSLDEERLERLLDALEE----LAIITHV 203
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
34-225 |
1.84e-04 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 42.98 E-value: 1.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 34 LVGVNGSGKSTImkiIAGLETAdsgtvsmqkglrigylaqqgeLTGEetvletlesvFEPQRRMEAELRSLEQEMAESGS 113
Cdd:cd03240 27 IVGQNGAGKTTI---IEALKYA---------------------LTGE----------LPPNSKGGAHDPKLIREGEVRAQ 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 114 DPEALRILGGKYDTLTREFERsngygWRSSV---QGVLAGLELREfqdmkTGLLSGGERT------RLCLGRMLLTEPDL 184
Cdd:cd03240 73 VKLAFENANGKKYTITRSLAI-----LENVIfchQGESNWPLLDM-----RGRCSGGEKVlasliiRLALAETFGSNCGI 142
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1226689869 185 LLLDEPTNHLDLKSIAW-----LEEYLAAFHGAVLVISHDRYFLDR 225
Cdd:cd03240 143 LALDEPTTNLDEENIEEslaeiIEERKSQKNFQLIVITHDEELVDA 188
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
9-220 |
1.96e-04 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 44.90 E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 9 VKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIagletadsgtvsmqkgLRIgyLAQQGELTGEETVLETLe 88
Cdd:TIGR01271 1225 AKYTEAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSAL----------------LRL--LSTEGEIQIDGVSWNSV- 1285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 89 svfepqrrmeaelrSLEQEMAESGSDPEALRILGGKYDTLTREFER-SNGYGWRSSVQGVLAGLeLREFQD-----MKTG 162
Cdd:TIGR01271 1286 --------------TLQTWRKAFGVIPQKVFIFSGTFRKNLDPYEQwSDEEIWKVAEEVGLKSV-IEQFPDkldfvLVDG 1350
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 163 --LLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLA-AFHGAVLVISHDR 220
Cdd:TIGR01271 1351 gyVLSNGHKQLMCLARSILSKAKILLLDEPSAHLDPVTLQIIRKTLKqSFSNCTVILSEHR 1411
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
3-60 |
2.05e-04 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 43.32 E-value: 2.05e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 3 ILALQDVKKSF-GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:PRK10908 1 MIRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKI 59
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
2-62 |
2.09e-04 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 44.25 E-value: 2.09e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 2 IILALQDVK-KSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM 62
Cdd:COG3845 256 VVLEVENLSvRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRL 317
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
339-523 |
2.17e-04 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 43.69 E-value: 2.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 339 GDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGV----IRWGT----------GV------------- 391
Cdd:cd03289 15 GGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTEGDIqidgVSWNSvplqkwrkafGVipqkvfifsgtfr 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 392 -DLGYYDQHQSElhENKTVLDEVW-----DRFPrmeqyevrGALGLFLFTGDEVfepvstLSGGEKGRVALTELMLRKDN 465
Cdd:cd03289 95 kNLDPYGKWSDE--EIWKVAEEVGlksviEQFP--------GQLDFVLVDGGCV------LSHGHKQLMCLARSVLSKAK 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 466 VLLLDEPTNHLDMDSREALENALSD-FPGTIISVSHDRYFINRFAEKVWVLDGNEIKEY 523
Cdd:cd03289 159 ILLLDEPSAHLDPITYQVIRKTLKQaFADCTVILSEHRIEAMLECQRFLVIEENKVRQY 217
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
8-107 |
2.54e-04 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 42.62 E-value: 2.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 8 DVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETadSGTVS---MQKGL--------RIGYLAQQGE 76
Cdd:cd03232 12 TVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKT--AGVITgeiLINGRpldknfqrSTGYVEQQDV 89
|
90 100 110
....*....|....*....|....*....|.
gi 1226689869 77 LTGEETVLETLesvfepqrRMEAELRSLEQE 107
Cdd:cd03232 90 HSPNLTVREAL--------RFSALLRGLSVE 112
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
4-60 |
2.78e-04 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 43.81 E-value: 2.78e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVkkSFGTHE---VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:PRK10522 323 LELRNV--TFAYQDngfSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEI 380
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
334-522 |
3.05e-04 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 43.16 E-value: 3.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 334 LSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGViRWGTGVDLG----YYDQHQSELHENKTV 409
Cdd:PRK14271 27 LTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGY-RYSGDVLLGgrsiFNYRDVLEFRRRVGM 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 410 LDEVWDRFPR---------------MEQYEVRGA-------LGLFLFTGDEVFEPVSTLSGGEKGRVALTELMLRKDNVL 467
Cdd:PRK14271 106 LFQRPNPFPMsimdnvlagvrahklVPRKEFRGVaqarlteVGLWDAVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVL 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 468 LLDEPTNHLDMDSREALENALSDFPG--TIISVSHDRYFINRFAEKVWV-LDGNEIKE 522
Cdd:PRK14271 186 LLDEPTSALDPTTTEKIEEFIRSLADrlTVIIVTHNLAQAARISDRAALfFDGRLVEE 243
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
358-500 |
3.59e-04 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 43.85 E-value: 3.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 358 ALIGDNGTGKSTLLQCLIGVEKPDAGVIRWG-----TGVD-----LGYYDQHQSELH-----ENKTVLDEVWDRFPRMEQ 422
Cdd:TIGR01257 960 AFLGHNGAGKTTTLSILTGLLPPTSGTVLVGgkdieTNLDavrqsLGMCPQHNILFHhltvaEHILFYAQLKGRSWEEAQ 1039
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 423 YEVRGAL---GLFLFTGDEvfepVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLDMDSREALENALSDFPG--TIIS 497
Cdd:TIGR01257 1040 LEMEAMLedtGLHHKRNEE----AQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSgrTIIM 1115
|
...
gi 1226689869 498 VSH 500
Cdd:TIGR01257 1116 STH 1118
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1-209 |
3.62e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 42.87 E-value: 3.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSF-GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkglrigylaqqGELTG 79
Cdd:PRK13652 1 MHLIETRDLCYSYsGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIR-----------GEPIT 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 80 EETVLETLESVFEPQRRMEAELRS--LEQEMA----ESGSDPEALRilggkydtltrefersngygwrSSVQGVLAGLEL 153
Cdd:PRK13652 70 KENIREVRKFVGLVFQNPDDQIFSptVEQDIAfgpiNLGLDEETVA----------------------HRVSSALHMLGL 127
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 154 REFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAF 209
Cdd:PRK13652 128 EELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDL 183
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
27-224 |
3.66e-04 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 42.74 E-value: 3.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 27 QDGERMGLVGVNGSGKSTIMKIIAGLETADsgtvsmqkglrigyLAQQGELTGEETVLE-----TLESVFEpqRRMEAEL 101
Cdd:cd03236 24 REGQVLGLVGPNGIGKSTALKILAGKLKPN--------------LGKFDDPPDWDEILDefrgsELQNYFT--KLLEGDV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 102 RSLEQemaesgsdPEALRIL-----GGKYDTLTREFERSNgygwrssVQGVLAGLELREFQDMKTGLLSGGERTRLCLGR 176
Cdd:cd03236 88 KVIVK--------PQYVDLIpkavkGKVGELLKKKDERGK-------LDELVDQLELRHVLDRNIDQLSGGELQRVAIAA 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 177 MLLTEPDLLLLDEPTNHLDLK---SIAWLEEYLAAFHGAVLVISHDRYFLD 224
Cdd:cd03236 153 ALARDADFYFFDEPSSYLDIKqrlNAARLIRELAEDDNYVLVVEHDLAVLD 203
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
26-81 |
4.04e-04 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 41.79 E-value: 4.04e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 26 LQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkGLRIGYLAQQGELTGEE 81
Cdd:cd03222 22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWD-GITPVYKPQYIDLSGGE 76
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
439-502 |
4.74e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 43.35 E-value: 4.74e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 439 VFEPVSTLSGGEKG------RVALTELMLRKDNVLLLDEPTNHLDMDSREALENAL-------SDFPGTIIsVSHDR 502
Cdd:PRK01156 795 MVEGIDSLSGGEKTavafalRVAVAQFLNNDKSLLIMDEPTAFLDEDRRTNLKDIIeyslkdsSDIPQVIM-ISHHR 870
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
6-63 |
4.98e-04 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 41.87 E-value: 4.98e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 6 LQDVKKSFG------THEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLE--TADSGTVSMQ 63
Cdd:COG2401 27 VAIVLEAFGvelrvvERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDVP 92
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
328-520 |
5.05e-04 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 42.89 E-value: 5.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 328 VLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDA--GVIRWgTGVDL-----------G 394
Cdd:TIGR02633 1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTwdGEIYW-SGSPLkasnirdteraG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 395 YYDQHQS-ELHENKTVLD------EVWDRFPRMEQYEV----RGALGLFLFTGDEVFEPVSTLSGGEKGRVALTELMLRK 463
Cdd:TIGR02633 80 IVIIHQElTLVPELSVAEniflgnEITLPGGRMAYNAMylraKNLLRELQLDADNVTRPVGDYGGGQQQLVEIAKALNKQ 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 464 DNVLLLDEPTNHLDMDSREALENALSDFPG---TIISVSHDRYFINRFAEKVWVL-DGNEI 520
Cdd:TIGR02633 160 ARLLILDEPSSSLTEKETEILLDIIRDLKAhgvACVYISHKLNEVKAVCDTICVIrDGQHV 220
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
3-219 |
5.17e-04 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 42.28 E-value: 5.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ----KGLRIGYLAQQG--- 75
Cdd:PRK11300 5 LLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRgqhiEGLPGHQIARMGvvr 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 76 -----ELTGEETVLETLesvfepqrrMEAELRSLEQemaesgsdpealRILGGKYDTltREFERSNgygwRSSVQGVLAG 150
Cdd:PRK11300 85 tfqhvRLFREMTVIENL---------LVAQHQQLKT------------GLFSGLLKT--PAFRRAE----SEALDRAATW 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 151 LE---LREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAF---HG-AVLVISHD 219
Cdd:PRK11300 138 LErvgLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELrneHNvTVLLIEHD 213
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
327-522 |
5.56e-04 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 42.21 E-value: 5.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 327 DVLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEK--PDAGVI--RWGTGVDLgyYDQHQSE 402
Cdd:PRK14247 2 NKIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIElyPEARVSgeVYLDGQDI--FKMDVIE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 403 LHENKTVLDEVWDRFPRMEQYE---------------------VRGAL---GLFLFTGDEVFEPVSTLSGGEKGRVALTE 458
Cdd:PRK14247 80 LRRRVQMVFQIPNPIPNLSIFEnvalglklnrlvkskkelqerVRWALekaQLWDEVKDRLDAPAGKLSGGQQQRLCIAR 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1226689869 459 LMLRKDNVLLLDEPTNHLDMDSREALENALSDFPG--TIISVSHDRYFINRFAEKVWVLDGNEIKE 522
Cdd:PRK14247 160 ALAFQPEVLLADEPTANLDPENTAKIESLFLELKKdmTIVLVTHFPQQAARISDYVAFLYKGQIVE 225
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
17-198 |
5.66e-04 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 42.78 E-value: 5.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 17 EVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ----KGLRIGYLAQQGELTGEETVLetlesvFE 92
Cdd:TIGR02203 346 PALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDghdlADYTLASLRRQVALVSQDVVL------FN 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 93 pqrrmeaelrsleqemaesgsDPEALRILGGKYDTLTREfersngygwrsSVQGVLAGLELREFQD-----------MKT 161
Cdd:TIGR02203 420 ---------------------DTIANNIAYGRTEQADRA-----------EIERALAAAYAQDFVDklplgldtpigENG 467
|
170 180 190
....*....|....*....|....*....|....*..
gi 1226689869 162 GLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKS 198
Cdd:TIGR02203 468 VLLSGGQRQRLAIARALLKDAPILILDEATSALDNES 504
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
359-520 |
5.69e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 42.53 E-value: 5.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 359 LIGDNGTGKSTLLQCLIGVEKPDAGVIRWGtgvDLgYYDQHQSELHENKTVLDEVWDRFPRME----------QYEvrga 428
Cdd:PRK13631 57 IIGNSGSGKSTLVTHFNGLIKSKYGTIQVG---DI-YIGDKKNNHELITNPYSKKIKNFKELRrrvsmvfqfpEYQ---- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 429 lgLFLFT--GDEVFEPVS-------------------------------TLSGGEKGRVALTELMLRKDNVLLLDEPTNH 475
Cdd:PRK13631 129 --LFKDTieKDIMFGPVAlgvkkseakklakfylnkmglddsylerspfGLSGGQKRRVAIAGILAIQPEILIFDEPTAG 206
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1226689869 476 LDMDSREALENALSDFPG---TIISVSHDRYFINRFAEKVWVLDGNEI 520
Cdd:PRK13631 207 LDPKGEHEMMQLILDAKAnnkTVFVITHTMEHVLEVADEVIVMDKGKI 254
|
|
| COG3950 |
COG3950 |
Predicted ATP-binding protein involved in virulence [General function prediction only]; |
344-519 |
6.59e-04 |
|
Predicted ATP-binding protein involved in virulence [General function prediction only];
Pssm-ID: 443150 [Multi-domain] Cd Length: 276 Bit Score: 41.91 E-value: 6.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 344 FRDLKMHVRAGDRI-ALIGDNGTGKSTLLQCL----------IGVEKPDAGVIRWGTGVD----LGYYDQH--------- 399
Cdd:COG3950 14 FEDLEIDFDNPPRLtVLVGENGSGKTTLLEAIalalsgllsrLDDVKFRKLLIRNGEFGDsaklILYYGTSrllldgplk 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 400 ----------------------QSELHENKTVLDEVWDR-----------------------FPRMEQYEVRGALGLFLF 434
Cdd:COG3950 94 klerlkeeyfsrldgydslldeDSNLREFLEWLREYLEDlenklsdeldekleavrealnklLPDFKDIRIDRDPGRLVI 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 435 --TGDEVFePVSTLSGGEKGRVALT-ELMLRKDN-------------VLLLDEPTNHLDMD-SREALENALSDFPGT-II 496
Cdd:COG3950 174 ldKNGEEL-PLNQLSDGERSLLALVgDLARRLAElnpalenplegegIVLIDEIDLHLHPKwQRRILPDLRKIFPNIqFI 252
|
250 260
....*....|....*....|....
gi 1226689869 497 SVSHDRYFI-NRFAEKVWVLDGNE 519
Cdd:COG3950 253 VTTHSPLILsSLEDEEVIVLERDE 276
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
3-63 |
6.69e-04 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 41.99 E-value: 6.69e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ 63
Cdd:PRK11248 1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLD 61
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
1-257 |
7.16e-04 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 42.02 E-value: 7.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFGTHE----VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLetadsgtvsmqkglrigyLAQQGE 76
Cdd:PRK09473 10 DALLDVKDLRVTFSTPDgdvtAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGL------------------LAANGR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 77 LTGEETvLETLESVFEPQR---RMEAElrsleqEMAESGSDPEA-----LRIlggkYDTLTREFERSNGYG----WRSSV 144
Cdd:PRK09473 72 IGGSAT-FNGREILNLPEKelnKLRAE------QISMIFQDPMTslnpyMRV----GEQLMEVLMLHKGMSkaeaFEESV 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 145 QGVLAGL--ELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIA----WLEEYLAAFHGAVLVISH 218
Cdd:PRK09473 141 RMLDAVKmpEARKRMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAqimtLLNELKREFNTAIIMITH 220
|
250 260 270
....*....|....*....|....*....|....*....
gi 1226689869 219 DryfLDRVCGRMAELLLgnveTYSGNYTEYLEKRTTVYE 257
Cdd:PRK09473 221 D---LGVVAGICDKVLV----MYAGRTMEYGNARDVFYQ 252
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
18-60 |
8.02e-04 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 41.61 E-value: 8.02e-04
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1226689869 18 VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:PRK13633 25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKV 67
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
8-233 |
9.12e-04 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 41.87 E-value: 9.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 8 DVKKSF----GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmqkglrigYLAQQGELTGEETV 83
Cdd:PRK11308 16 PVKRGLfkpeRLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGEL---------YYQGQDLLKADPEA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 84 LETLES----VFE-------PQRRMEAELRsleqemaesgsdpEALRIlggkYDTLTREfERsngygwRSSVQGVLAGLE 152
Cdd:PRK11308 87 QKLLRQkiqiVFQnpygslnPRKKVGQILE-------------EPLLI----NTSLSAA-ER------REKALAMMAKVG 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 153 LR-EFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLkSI--------AWLEEylaAFHGAVLVISHD---- 219
Cdd:PRK11308 143 LRpEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDV-SVqaqvlnlmMDLQQ---ELGLSYVFISHDlsvv 218
|
250
....*....|....*...
gi 1226689869 220 RYFLDRVC----GRMAEL 233
Cdd:PRK11308 219 EHIADEVMvmylGRCVEK 236
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
3-70 |
9.44e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 41.60 E-value: 9.44e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSF--GThEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsMQKGLRIGY 70
Cdd:PRK13639 1 ILETRDLKYSYpdGT-EALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEV-LIKGEPIKY 68
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
9-46 |
9.99e-04 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 41.38 E-value: 9.99e-04
10 20 30
....*....|....*....|....*....|....*...
gi 1226689869 9 VKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIM 46
Cdd:cd03289 10 AKYTEGGNAVLENISFSISPGQRVGLLGRTGSGKSTLL 47
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
14-56 |
1.00e-03 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 41.81 E-value: 1.00e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1226689869 14 GTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLE------TAD 56
Cdd:COG4170 18 GRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITkdnwhvTAD 66
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
10-51 |
1.16e-03 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 40.71 E-value: 1.16e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 1226689869 10 KKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAG 51
Cdd:cd03233 14 GKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALAN 55
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
15-49 |
1.28e-03 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 41.62 E-value: 1.28e-03
10 20 30
....*....|....*....|....*....|....*
gi 1226689869 15 THEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKII 49
Cdd:PRK10789 327 DHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLI 361
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
4-219 |
1.34e-03 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 40.54 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETAD---SGTVSM-----------QKglRIG 69
Cdd:COG4136 2 LSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsaSGEVLLngrrltalpaeQR--RIG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 70 YLAQQGELTGEETVLETL-----ESVFEPQRRMEAElrsleqemaesgsdpEALRILGgkydtltrefersngygwrssv 144
Cdd:COG4136 80 ILFQDDLLFPHLSVGENLafalpPTIGRAQRRARVE---------------QALEEAG---------------------- 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 145 qgvLAGLELRefqDMKTglLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD----LKSIAWLEEYLAAFHGAVLVISHD 219
Cdd:COG4136 123 ---LAGFADR---DPAT--LSGGQRARVALLRALLAEPRALLLDEPFSKLDaalrAQFREFVFEQIRQRGIPALLVTHD 193
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
1-61 |
1.36e-03 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 41.33 E-value: 1.36e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 1 MIILALQDVKKSFGTHE----VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLeTADSGTVS 61
Cdd:PRK15093 1 MPLLDIRNLTIEFKTSDgwvkAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGV-TKDNWRVT 64
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
346-521 |
1.63e-03 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 40.84 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 346 DLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIrwgtgvdlgYYDQHQSELHEN------------------- 406
Cdd:PRK13633 28 DVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKV---------YVDGLDTSDEENlwdirnkagmvfqnpdnqi 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 407 -KTVLDEVWDRFPR---MEQYEVRGALglflftgDEVFEPVST----------LSGGEKGRVALTELMLRKDNVLLLDEP 472
Cdd:PRK13633 99 vATIVEEDVAFGPEnlgIPPEEIRERV-------DESLKKVGMyeyrrhaphlLSGGQKQRVAIAGILAMRPECIIFDEP 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 473 TNHLDMDSREALENALSDFPG----TIISVSHdryFINRFAE--KVWVLDGNEIK 521
Cdd:PRK13633 172 TAMLDPSGRREVVNTIKELNKkygiTIILITH---YMEEAVEadRIIVMDSGKVV 223
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
17-60 |
1.69e-03 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 41.55 E-value: 1.69e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1226689869 17 EVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:PTZ00265 399 EIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDI 442
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
4-84 |
1.75e-03 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 41.34 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 4 LALQDVkkSFG---THEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM---------QKGLR--IG 69
Cdd:COG5265 358 VRFENV--SFGydpERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIdgqdirdvtQASLRaaIG 435
|
90
....*....|....*
gi 1226689869 70 YLAQqgeltgeETVL 84
Cdd:COG5265 436 IVPQ-------DTVL 443
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
19-149 |
2.07e-03 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 40.39 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM----------QKGLR-----IGYLAQQGELT-GEET 82
Cdd:PRK13634 23 LYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIgervitagkkNKKLKplrkkVGIVFQFPEHQlFEET 102
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1226689869 83 VLETLesVFEPQ----RRMEAELRSleqemaesgsdPEALRILGGKYDTLTRE-FERSNGYGWRSSVQGVLA 149
Cdd:PRK13634 103 VEKDI--CFGPMnfgvSEEDAKQKA-----------REMIELVGLPEELLARSpFELSGGQMRRVAIAGVLA 161
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
29-60 |
2.17e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 38.89 E-value: 2.17e-03
10 20 30
....*....|....*....|....*....|..
gi 1226689869 29 GERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGGV 33
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
3-236 |
2.43e-03 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 41.15 E-value: 2.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVKKSF-GTHE-VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSG--TVSMQKGL--------RIGY 70
Cdd:TIGR01257 1937 ILRLNELTKVYsGTSSpAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGdaTVAGKSILtnisdvhqNMGY 2016
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 71 LAQ----QGELTGEETVLetlesvfepqrrMEAELRSLEQEmaesgsdpealrilggkydtltrEFERSNGYGWRSsvqg 146
Cdd:TIGR01257 2017 CPQfdaiDDLLTGREHLY------------LYARLRGVPAE-----------------------EIEKVANWSIQS---- 2057
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 147 vlagLELREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLAAF---HGAVLVISHDRYFL 223
Cdd:TIGR01257 2058 ----LGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIireGRAVVLTSHSMEEC 2133
|
250
....*....|...
gi 1226689869 224 DRVCGRMAELLLG 236
Cdd:TIGR01257 2134 EALCTRLAIMVKG 2146
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
326-500 |
2.74e-03 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 40.02 E-value: 2.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 326 DDVLMTEGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQC------LIgvekPDAGVirWGT----GVDLgy 395
Cdd:COG1117 9 EPKIEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRClnrmndLI----PGARV--EGEilldGEDI-- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 396 YDQHQS------------------------------ELHE--NKTVLDEVwdrfprmeqyeVRGAL---GLFlftgDEV- 439
Cdd:COG1117 81 YDPDVDvvelrrrvgmvfqkpnpfpksiydnvayglRLHGikSKSELDEI-----------VEESLrkaALW----DEVk 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1226689869 440 ---FEPVSTLSGGEKGR------VALtelmlrKDNVLLLDEPTNHLDMDSREALENAL----SDFpgTIISVSH 500
Cdd:COG1117 146 drlKKSALGLSGGQQQRlciaraLAV------EPEVLLMDEPTSALDPISTAKIEELIlelkKDY--TIVIVTH 211
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
8-217 |
2.83e-03 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 40.63 E-value: 2.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 8 DVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADS--GTV-------SMQKGLRIGYLAQQGELT 78
Cdd:PLN03211 73 DETRQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNNftGTIlannrkpTKQILKRTGFVTQDDILY 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 79 GEETVLETLesVFEPQRRM------EAELRSLEQEMAESGSDPEALRILGGKYdtltrefersngygwrssVQGVlagle 152
Cdd:PLN03211 153 PHLTVRETL--VFCSLLRLpksltkQEKILVAESVISELGLTKCENTIIGNSF------------------IRGI----- 207
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1226689869 153 lrefqdmktgllSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYLA--AFHGAVLVIS 217
Cdd:PLN03211 208 ------------SGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLGslAQKGKTIVTS 262
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
347-477 |
3.02e-03 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 40.70 E-value: 3.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 347 LKMHVRAGDRIALIGDNGTGKSTLLQCLIG-VEKPDAGVIRWGTgvdLGYYDQhQSELhENKTVLDEVWDRFPRMEQY-- 423
Cdd:TIGR00957 657 ITFSIPEGALVAVVGQVGCGKSSLLSALLAeMDKVEGHVHMKGS---VAYVPQ-QAWI-QNDSLRENILFGKALNEKYyq 731
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1226689869 424 EVRGALGLF-----LFTGD--EVFEPVSTLSGGEKGRVALTELMLRKDNVLLLDEPTNHLD 477
Cdd:TIGR00957 732 QVLEACALLpdleiLPSGDrtEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVD 792
|
|
| prfA |
PRK00591 |
peptide chain release factor 1; Validated |
577-634 |
3.08e-03 |
|
peptide chain release factor 1; Validated
Pssm-ID: 234801 [Multi-domain] Cd Length: 359 Bit Score: 40.06 E-value: 3.08e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1226689869 577 EQAIARAEKEAGEMEAELADPEIWKDPDKAAETTRRYNALKdEIERLYEQYDALESSL 634
Cdd:PRK00591 5 LDKLEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELE-PIVEAYREYKQAQEDL 61
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
332-386 |
3.46e-03 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 40.49 E-value: 3.46e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1226689869 332 EGLSKGYGDRILFRDLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVIR 386
Cdd:NF033858 5 EGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVE 59
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
19-62 |
3.55e-03 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 40.39 E-value: 3.55e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM 62
Cdd:PRK11176 359 LRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILL 402
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
14-60 |
4.33e-03 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 39.33 E-value: 4.33e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1226689869 14 GTHeVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV 60
Cdd:PRK13647 17 GTK-ALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRV 62
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
5-219 |
5.46e-03 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 39.16 E-value: 5.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 5 ALQDVKKSFGTHEVLKS---------VSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQ---------KGL 66
Cdd:cd03294 17 AFKLLAKGKSKEEILKKtgqtvgvndVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDgqdiaamsrKEL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 67 R------IGYLAQQGELTGEETVLETLESVFEPQRRMEAElrslEQEMAEsgsdpEALRilggkydtltrefersngygw 140
Cdd:cd03294 97 RelrrkkISMVFQSFALLPHRTVLENVAFGLEVQGVPRAE----REERAA-----EALE--------------------- 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 141 rssvqgvLAGLElrEFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLD-LKSIAWLEEYL---AAFHGAVLVI 216
Cdd:cd03294 147 -------LVGLE--GWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDpLIRREMQDELLrlqAELQKTIVFI 217
|
...
gi 1226689869 217 SHD 219
Cdd:cd03294 218 THD 220
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
19-62 |
5.78e-03 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 39.60 E-value: 5.78e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1226689869 19 LKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM 62
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTL 311
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
18-192 |
6.76e-03 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 39.35 E-value: 6.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 18 VLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQKGLRIGYLAQQGELTgeetvLETL-ESVFEPQRR 96
Cdd:TIGR00954 467 LIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKPAKGKLFYVPQRPYMT-----LGTLrDQIIYPDSS 541
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 97 MEAELRSLeqemaeSGSDPEALRILGGKYDTLTREFersngyGWrSSVQgvlaglelrEFQDmktgLLSGGERTRLCLGR 176
Cdd:TIGR00954 542 EDMKRRGL------SDKDLEQILDNVQLTHILEREG------GW-SAVQ---------DWMD----VLSGGEKQRIAMAR 595
|
170
....*....|....*.
gi 1226689869 177 MLLTEPDLLLLDEPTN 192
Cdd:TIGR00954 596 LFYHKPQFAILDECTS 611
|
|
| PrfA |
COG0216 |
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ... |
589-634 |
6.97e-03 |
|
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors
Pssm-ID: 439986 [Multi-domain] Cd Length: 356 Bit Score: 39.21 E-value: 6.97e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1226689869 589 EMEAELADPEIWKDPDKAAETTRRYNALKdEIERLYEQYDALESSL 634
Cdd:COG0216 15 ELEALLSDPEVISDQKRFRKLSKEYAELE-PIVEAYREYKKLLEDI 59
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-219 |
7.30e-03 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 38.69 E-value: 7.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 1 MIILALQDVKKSFG----THEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSMQkGLRI-------G 69
Cdd:COG4525 1 MSMLTVRHVSVRYPgggqPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLD-GVPVtgpgadrG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 70 YLAQQGELTGEETVLE------TLESVFEPQRRMEAElrsleqemaesgsdpEALRILGgkydtltrefersngygwrss 143
Cdd:COG4525 80 VVFQKDALLPWLNVLDnvafglRLRGVPKAERRARAE---------------ELLALVG--------------------- 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 144 vqgvlagleLREFQDMKTGLLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKSIAWLEEYL----AAFHGAVLVISHD 219
Cdd:COG4525 124 ---------LADFARRRIWQLSGGMRQRVGIARALAADPRFLLMDEPFGALDALTREQMQELLldvwQRTGKGVFLITHS 194
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
3-63 |
7.40e-03 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 38.62 E-value: 7.40e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1226689869 3 ILALQDVKKSFGTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLE--TADSGTVSMQ 63
Cdd:PRK09580 1 MLSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFK 63
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
3-240 |
7.82e-03 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 39.26 E-value: 7.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 3 ILALQDVkksfgTHEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVsmqkglrigYLAQQgELTGEET 82
Cdd:PRK15439 268 VLTVEDL-----TGEGFRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRI---------MLNGK-EINALST 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 83 vletlesvfepQRRMEAELRSLEQEMAESG---SDPEALRILGGKYDTLT------RE---FERsngygWRSSVQGVLAG 150
Cdd:PRK15439 333 -----------AQRLARGLVYLPEDRQSSGlylDAPLAWNVCALTHNRRGfwikpaREnavLER-----YRRALNIKFNH 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 151 LElrefQDMKTglLSGGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKS---IAWLEEYLAAFHGAVLVISHD----RYFL 223
Cdd:PRK15439 397 AE----QAART--LSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSArndIYQLIRSIAAQNVAVLFISSDleeiEQMA 470
|
250 260
....*....|....*....|....
gi 1226689869 224 DRVC----GRMAELLLG---NVET 240
Cdd:PRK15439 471 DRVLvmhqGEISGALTGaaiNVDT 494
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
326-385 |
8.64e-03 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 38.62 E-value: 8.64e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1226689869 326 DDVLMTEGLSKGYGDRI-LFR--------DLKMHVRAGDRIALIGDNGTGKSTLLQCLIGVEKPDAGVI 385
Cdd:PRK15112 2 ETLLEVRNLSKTFRYRTgWFRrqtveavkPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGEL 70
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
16-62 |
8.67e-03 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 38.61 E-value: 8.67e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1226689869 16 HEVLKSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTVSM 62
Cdd:PRK13646 20 HQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTV 66
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
20-267 |
9.57e-03 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 39.00 E-value: 9.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 20 KSVSFTLQDGERMGLVGVNGSGKSTIMKIIAGLETADSGTV--------------SMQKGlrIGYLAQQGELTGeetvle 85
Cdd:PRK09700 280 RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIrlngkdisprspldAVKKG--MAYITESRRDNG------ 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 86 tlesvFEPQRrmeaelrSLEQEMAESGSDPEALriLGGKYDTLTREFERSNGYGWRSSVQGVLAGLElrefQDMktGLLS 165
Cdd:PRK09700 352 -----FFPNF-------SIAQNMAISRSLKDGG--YKGAMGLFHEVDEQRTAENQRELLALKCHSVN----QNI--TELS 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1226689869 166 GGERTRLCLGRMLLTEPDLLLLDEPTNHLDLKS---IAWLEEYLAAFHGAVLVISHDRYFLDRVCGRMAELLLGNVetys 242
Cdd:PRK09700 412 GGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAkaeIYKVMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRL---- 487
|
250 260
....*....|....*....|....*
gi 1226689869 243 gnyTEYLEKRTTVYENRMRAWKLQQ 267
Cdd:PRK09700 488 ---TQILTNRDDMSEEEIMAWALPQ 509
|
|
| |
