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Conserved domains on  [gi|1238650805|ref|WP_095333138|]
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ABC transporter ATP-binding protein [Helicobacter sp. 11S02596-1]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11467437)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including Fe(3+) ions and polyamines such as spermidine and putrescine

CATH:  3.40.50.300
EC:  7.-.-.-
Gene Ontology:  GO:0042626|GO:0140359|GO:0005524|GO:0016887
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-227 3.88e-91

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


:

Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 274.28  E-value: 3.88e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELDFE---KTLDGNhgTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDshkgfnLPI 77
Cdd:COG3842     3 MPALELEnvsKRYGDV--TALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTG------LPP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  78 QQRKIGFVFQNYALFPHLNVYENIIFGHSGDKT-------RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSP 150
Cdd:COG3842    75 EKRNVGMVFQDYALFPHLTVAENVAFGLRMRGVpkaeiraRVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEP 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805 151 DILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL--SDRFSA 227
Cdd:COG3842   155 RVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYErpATRFVA 233
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-227 3.88e-91

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 274.28  E-value: 3.88e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELDFE---KTLDGNhgTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDshkgfnLPI 77
Cdd:COG3842     3 MPALELEnvsKRYGDV--TALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTG------LPP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  78 QQRKIGFVFQNYALFPHLNVYENIIFGHSGDKT-------RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSP 150
Cdd:COG3842    75 EKRNVGMVFQDYALFPHLTVAENVAFGLRMRGVpkaeiraRVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEP 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805 151 DILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL--SDRFSA 227
Cdd:COG3842   155 RVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYErpATRFVA 233
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 1-214 1.93e-89

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 264.93  E-value: 1.93e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELDFEKTLDGnhgtFLLQVSLKLPrGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQR 80
Cdd:cd03297     1 MLCVDIEKRLPD----FTLKIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKKINLPPQQR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  81 KIGFVFQNYALFPHLNVYENIIFGHSG-----DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLL 155
Cdd:cd03297    76 KIGLVFQQYALFPHLNVRENLAFGLKRkrnreDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLL 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805 156 DEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRG 214
Cdd:cd03297   156 DEPFSALDRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 2-219 1.40e-69

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 219.21  E-value: 1.40e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   2 IELDFEKTLdgnhGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRK 81
Cdd:TIGR02142   1 LSARFSKRL----GDFSLDADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKGIFLPPEKRR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  82 IGFVFQNYALFPHLNVYENIIFGHS---GDKTRI--EEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLD 156
Cdd:TIGR02142  77 IGYVFQEARLFPHLSVRGNLRYGMKrarPSERRIsfERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMD 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 157 EPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:TIGR02142 157 EPLAALDDPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEV 219
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
2-220 1.93e-67

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 214.43  E-value: 1.93e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   2 IEL-DFEKTLDGNhgTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQQR 80
Cdd:PRK09452   15 VELrGISKSFDGK--EVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRI------MLDGQDITHVPAENR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  81 KIGFVFQNYALFPHLNVYENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDIL 153
Cdd:PRK09452   87 HVNTVFQSYALFPHMTVFENVAFGlrmqktpAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVL 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 154 LLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK09452  167 LLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIY 233
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
18-271 8.08e-60

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 193.75  E-value: 8.08e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQQRKIGFVFQNYALFPHLNV 97
Cdd:NF040840   16 LRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKI------YLDGKDITNLPPEKRGIAYVYQNYMLFPHKTV 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:NF040840   90 FENIAFGlklrkvpKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALDVQTRDEL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 171 QEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL--SDRFSAKLQINGEILK--ITPQSLITI 246
Cdd:NF040840  170 IREMKRWHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRrpKNEFVARFVGFENIIEgvAEKGGEGTI 249

                         250       260
                  ....*....|....*....|....*
gi 1238650805 247 VDVlsNGsiVRIVLAPSEAKHFRVG 271
Cdd:NF040840  250 LDT--GN--IKIELPEEKKGKVRIG 270
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 18-160 1.85e-40

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 137.78  E-value: 1.85e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdSHKGFNLPIQQRKIGFVFQNYALFPHLNV 97
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQ----DLTDDERKSLRKEIGYVFQDPQLFPRLTV 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1238650805  98 YENIIFG-------HSGDKTRIEEVMALMELDGLSKKKI----TALSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:pfam00005  77 RENLRLGlllkglsKREKDARAEEALEKLGLGDLADRPVgerpGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
18-195 6.82e-26

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 100.77  E-value: 6.82e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkgfnlpiqqRKIGFVFQNYAL---FPh 94
Cdd:NF040873    8 LHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGG---------------ARVAYVPQRSEVpdsLP- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENI---IFGHSG--------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALD 163
Cdd:NF040873   72 LTVRDLVamgRWARRGlwrrltrdDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLD 151

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1238650805 164 GEMRSKLQEELKRLIAHfGITAFLVSHDLGEV 195
Cdd:NF040873  152 AESRERIIALLAEEHAR-GATVVVVTHDLELV 182
GguA NF040905
sugar ABC transporter ATP-binding protein;
18-209 1.54e-18

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 85.23  E-value: 1.54e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGL------EnpdkGRIVV-GNRVYF----DShkgfnlpiQQRKIGFVF 86
Cdd:NF040905   17 LDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVyphgsyE----GEILFdGEVCRFkdirDS--------EALGIVIIH 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  87 QNYALFPHLNVYENIIFGHSGDK----------TRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLD 156
Cdd:NF040905   85 QELALIPYLSIAENIFLGNERAKrgvidwnetnRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLILD 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 157 EPLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGK 209
Cdd:NF040905  165 EPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGR 216
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
20-163 5.39e-11

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 62.83  E-value: 5.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRI-VVGNRVyfDSHkgfNLPIQQRkIGFVFQNYALFPHLNVY 98
Cdd:NF033858  284 HVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAwLFGQPV--DAG---DIATRRR-VGYMSQAFSLYGELTVR 357

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1238650805  99 ENI-----IFGHSGDKT--RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALD 163
Cdd:NF033858  358 QNLelharLFHLPAAEIaaRVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD 429
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
109-240 3.57e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 59.75  E-value: 3.57e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 109 KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHfGITAFLV 188
Cdd:NF000106  122 RARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLT 200

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 189 SHDLGEVFKLSDEVICLQDGKIAKRGTPDEVflsdrfsaKLQINGEILKITP 240
Cdd:NF000106  201 TQYMEEAEQLAHELTVIDRGRVIADGKVDEL--------KTKVGGRTLQIRP 244
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
18-158 1.71e-09

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 58.21  E-value: 1.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfdshkgFNLPIQQR--------KIGFVFQ-- 87
Cdd:NF033858   17 LDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEV-----------LGGDMADArhrravcpRIAYMPQgl 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  88 --NyaLFPHLNVYENI-----IFGHSGD--KTRIEEvmaLMELDGLSK-------KkitaLSGGQAQRVALARALASSPD 151
Cdd:NF033858   86 gkN--LYPTLSVFENLdffgrLFGQDAAerRRRIDE---LLRATGLAPfadrpagK----LSGGMKQKLGLCCALIHDPD 156


                  ....*..
gi 1238650805 152 ILLLDEP 158
Cdd:NF033858  157 LLILDEP 163
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 27-191 1.24e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 52.76  E-value: 1.24e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   27 RGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfdshkgfnlpiqqrkigfvfqnyalfphlnvyeniifgHS 106
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY-------------------------------------------ID 37

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  107 GDKTRIEEVMALMELDGLSKKKitALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE-----LKRLIAHF 181
Cdd:smart00382  38 GEDILEEVLDQLLLIIVGGKKA--SGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLeelrlLLLLKSEK 115

                          170
                   ....*....|
gi 1238650805  182 GITAFLVSHD 191
Cdd:smart00382 116 NLTVILTTND 125
GguA NF040905
sugar ABC transporter ATP-binding protein;
132-158 1.45e-03

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 39.77  E-value: 1.45e-03
                          10        20
                  ....*....|....*....|....*..
gi 1238650805 132 LSGGQAQRVALARALASSPDILLLDEP 158
Cdd:NF040905  405 LSGGNQQKVVLSKWLFTDPDVLILDEP 431
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-227 3.88e-91

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 274.28  E-value: 3.88e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELDFE---KTLDGNhgTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDshkgfnLPI 77
Cdd:COG3842     3 MPALELEnvsKRYGDV--TALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTG------LPP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  78 QQRKIGFVFQNYALFPHLNVYENIIFGHSGDKT-------RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSP 150
Cdd:COG3842    75 EKRNVGMVFQDYALFPHLTVAENVAFGLRMRGVpkaeiraRVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEP 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805 151 DILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL--SDRFSA 227
Cdd:COG3842   155 RVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYErpATRFVA 233
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 1-214 1.93e-89

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 264.93  E-value: 1.93e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELDFEKTLDGnhgtFLLQVSLKLPrGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQR 80
Cdd:cd03297     1 MLCVDIEKRLPD----FTLKIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKKINLPPQQR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  81 KIGFVFQNYALFPHLNVYENIIFGHSG-----DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLL 155
Cdd:cd03297    76 KIGLVFQQYALFPHLNVRENLAFGLKRkrnreDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLL 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805 156 DEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRG 214
Cdd:cd03297   156 DEPFSALDRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 5-220 9.44e-87

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 262.78  E-value: 9.44e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   5 DFEKTLDGNhgTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFdshkgFNLPIQQRKIGF 84
Cdd:COG1118     7 NISKRFGSF--TLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLF-----TNLPPRERRVGF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  85 VFQNYALFPHLNVYENIIFG-----HSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDE 157
Cdd:COG1118    80 VFQHYALFPHMTVAENIAFGlrvrpPSKAeiRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDE 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 158 PLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG1118   160 PFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVY 222
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 1-220 3.69e-84

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 256.57  E-value: 3.69e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELDFEKTLdgnhGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQR 80
Cdd:COG4148     2 MLEVDFRLRR----GGFTLDVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDSARGIFLPPHRR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  81 KIGFVFQNYALFPHLNVYENIIFGH-----SGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLL 155
Cdd:COG4148    78 RIGYVFQEARLFPHLSVRGNLLYGRkraprAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLM 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1238650805 156 DEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG4148   158 DEPLAALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVL 222
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 1-211 2.94e-83

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 248.97  E-value: 2.94e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELDFEKTLDGNHgtFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDshkgfnLPIQQR 80
Cdd:cd03259     1 LELKGLSKTYGSVR--ALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTG------VPPERR 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  81 KIGFVFQNYALFPHLNVYENIIFG---HSGDK----TRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDIL 153
Cdd:cd03259    73 NIGMVFQDYALFPHLTVAENIAFGlklRGVPKaeirARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLL 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 154 LLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIA 211
Cdd:cd03259   153 LLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIV 210
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 21-220 1.09e-74

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 227.89  E-value: 1.09e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfDSHkgfNLPIQQRKIGFVFQNYALFPHLNVYEN 100
Cdd:cd03300    19 VSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGK---DIT---NLPPHKRPVNTVFQNYALFPHLTVFEN 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE 173
Cdd:cd03300    93 IAFGlrlkklpKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALDLKLRKDMQLE 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1238650805 174 LKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:cd03300   173 LKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIY 219
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 21-220 9.54e-73

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 227.26  E-value: 9.54e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDshkgfnLPIQQRKIGFVFQNYALFPHLNVYEN 100
Cdd:COG3839    22 IDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTD------LPPKDRNIAMVFQSYALYPHMTVYEN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFG-----HSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE 173
Cdd:COG3839    96 IAFPlklrkVPKAeiDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAE 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1238650805 174 LKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG3839   176 IKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEELY 222
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 2-219 1.40e-69

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 219.21  E-value: 1.40e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   2 IELDFEKTLdgnhGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRK 81
Cdd:TIGR02142   1 LSARFSKRL----GDFSLDADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKGIFLPPEKRR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  82 IGFVFQNYALFPHLNVYENIIFGHS---GDKTRI--EEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLD 156
Cdd:TIGR02142  77 IGYVFQEARLFPHLSVRGNLRYGMKrarPSERRIsfERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMD 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 157 EPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:TIGR02142 157 EPLAALDDPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEV 219
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-203 7.66e-68

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 211.49  E-value: 7.66e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIEL-DFEKTLDGNHGTF--LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkgfnlPI 77
Cdd:COG1116     7 ALELrGVSKRFPTGGGGVtaLDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGK-----------PV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  78 QQ--RKIGFVFQNYALFPHLNVYENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALAS 148
Cdd:COG1116    76 TGpgPDRGVVFQEPALLPWLTVLDNVALGlelrgvpKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALAN 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1238650805 149 SPDILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVI 203
Cdd:COG1116   156 DPEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVV 210
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
2-220 1.93e-67

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 214.43  E-value: 1.93e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   2 IEL-DFEKTLDGNhgTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQQR 80
Cdd:PRK09452   15 VELrGISKSFDGK--EVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRI------MLDGQDITHVPAENR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  81 KIGFVFQNYALFPHLNVYENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDIL 153
Cdd:PRK09452   87 HVNTVFQSYALFPHMTVFENVAFGlrmqktpAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVL 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 154 LLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK09452  167 LLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIY 233
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 8-205 4.52e-67

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 208.09  E-value: 4.52e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   8 KTLDGNHGTF--LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkgfnlPIQQ--RKIG 83
Cdd:cd03293     8 KTYGGGGGAVtaLEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGE-----------PVTGpgPDRG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  84 FVFQNYALFPHLNVYENIIFG----HSGDKTRIEEVMALMELDGLS---KKKITALSGGQAQRVALARALASSPDILLLD 156
Cdd:cd03293    77 YVFQQDALLPWLTVLDNVALGlelqGVPKAEARERAEELLELVGLSgfeNAYPHQLSGGMRQRVALARALAVDPDVLLLD 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1238650805 157 EPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICL 205
Cdd:cd03293   157 EPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL 205
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 18-220 1.80e-66

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 207.19  E-value: 1.80e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshKGFNLPIQQRKIGFVFQNYALFPHLNV 97
Cdd:cd03296    18 LDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGE------DATDVPVQERNVGFVFQHYALFRHMTV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFG---------HSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:cd03296    92 FDNVAFGlrvkprserPPEAeiRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDAKV 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1238650805 167 RSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:cd03296   172 RKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVY 225
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 13-209 5.71e-66

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 203.96  E-value: 5.71e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  13 NHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDshKGFNLPIQQRKIGFVFQNYALF 92
Cdd:cd03229    11 GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTD--LEDELPPLRRRIGMVFQDFALF 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  93 PHLNVYENIIFGhsgdktrieevmalmeldglskkkitaLSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:cd03229    89 PHLTVLENIALG---------------------------LSGGQQQRVALARALAMDPDVLLLDEPTSALDPITRREVRA 141

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1238650805 173 ELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGK 209
Cdd:cd03229   142 LLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
21-227 1.82e-63

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 203.41  E-value: 1.82e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQQRKIGFVFQNYALFPHLNVYEN 100
Cdd:PRK11432   25 LNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQI------FIDGEDVTHRSIQQRDICMVFQSYALFPHMSLGEN 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE 173
Cdd:PRK11432   99 VGYGlkmlgvpKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREK 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 174 LKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL--SDRFSA 227
Cdd:PRK11432  179 IRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRqpASRFMA 234
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
1-230 3.07e-62

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 200.10  E-value: 3.07e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELDFEKTLdGNHgtfLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQR 80
Cdd:PRK11144    1 MLELNFKQQL-GDL---CLTVNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKGICLPPEKR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  81 KIGFVFQNYALFPHLNVYENIIFGHSG-DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:PRK11144   77 RIGYVFQDARLFPHYKVRGNLRYGMAKsMVAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPL 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 160 SALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSAKLQ 230
Cdd:PRK11144  157 ASLDLPRKRELLPYLERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWASSAMRPWLP 227
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 21-214 4.68e-62

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 195.17  E-value: 4.68e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDshkgfnLPIQQRKIGFVFQNYALFPHLNVYEN 100
Cdd:cd03301    19 LNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTD------LPPKDRDIAMVFQNYALYPHMTVYDN 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFG---HSGDK----TRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE 173
Cdd:cd03301    93 IAFGlklRKVPKdeidERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAKLRVQMRAE 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1238650805 174 LKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRG 214
Cdd:cd03301   173 LKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 33-228 1.25e-61

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 197.72  E-value: 1.25e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  33 IFGKSGAGKTTILRILSGLENPDKGRIVvgnrvyFDSHKGFNLPIQQRKIGFVFQNYALFPHLNVYENIIFGHSGDKT-- 110
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIM------LDGEDVTNVPPHLRHINMVFQSYALFPHMTVEENVAFGLKMRKVpr 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 111 -----RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHFGITA 185
Cdd:TIGR01187  75 aeikpRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITF 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1238650805 186 FLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL--SDRFSAK 228
Cdd:TIGR01187 155 VFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEepANLFVAR 199
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 17-220 9.95e-61

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 192.55  E-value: 9.95e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  17 FLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQQRKIGFVFQNYALFPHLN 96
Cdd:cd03299    14 KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKI------LLNGKDITNLPPEKRDISYVPQNYALFPHMT 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 VYENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSK 169
Cdd:cd03299    88 VYKNIAYGlkkrkvdKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEK 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 170 LQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:cd03299   168 LREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVF 218
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
18-271 8.08e-60

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 193.75  E-value: 8.08e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQQRKIGFVFQNYALFPHLNV 97
Cdd:NF040840   16 LRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKI------YLDGKDITNLPPEKRGIAYVYQNYMLFPHKTV 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:NF040840   90 FENIAFGlklrkvpKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALDVQTRDEL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 171 QEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL--SDRFSAKLQINGEILK--ITPQSLITI 246
Cdd:NF040840  170 IREMKRWHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRrpKNEFVARFVGFENIIEgvAEKGGEGTI 249

                         250       260
                  ....*....|....*....|....*
gi 1238650805 247 VDVlsNGsiVRIVLAPSEAKHFRVG 271
Cdd:NF040840  250 LDT--GN--IKIELPEEKKGKVRIG 270
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
21-225 9.41e-59

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 187.58  E-value: 9.41e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDSHKgfnlpiQQRKIGFVFQNYALFPHLNVYE 99
Cdd:COG1131    19 VSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVlGEDVARDPAE------VRRRIGYVPQEPALYPDLTVRE 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NI-----IFGHSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:COG1131    93 NLrffarLYGLPRKeaRERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTSGLDPEARRELWE 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 173 ELKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV---FLSDRF 225
Cdd:COG1131   173 LLREL-AAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELkarLLEDVF 227
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 20-222 1.02e-58

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 188.62  E-value: 1.02e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRKIGFVFQNYALFPHLNVYE 99
Cdd:cd03294    42 DVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRELRRKKISMVFQSFALLPHRTVLE 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NIIFG----HSGDKTRIE---EVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:cd03294   122 NVAFGlevqGVPRAEREEraaEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREMQD 201

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1238650805 173 ELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLS 222
Cdd:cd03294   202 ELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTN 251
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 1-221 2.39e-58

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 186.25  E-value: 2.39e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIEL-DFEKTLDGNHGTF--LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDShKGFNLPI 77
Cdd:cd03258     1 MIELkNVSKVFGDTGGKVtaLKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLL-SGKELRK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  78 QQRKIGFVFQNYALFPHLNVYENIIF----GHSGDKTRIEEVMALMELDGLSKKK---ITALSGGQAQRVALARALASSP 150
Cdd:cd03258    80 ARRRIGMIFQHFNLLSSRTVFENVALpleiAGVPKAEIEERVLELLELVGLEDKAdayPAQLSGGQKQRVGIARALANNP 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 151 DILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL 221
Cdd:cd03258   160 KVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFA 230
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 18-210 4.26e-58

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 185.00  E-value: 4.26e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRKIGFVFQNYALFPHLNV 97
Cdd:cd03255    20 LKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFRRRHIGFVFQSFNLLPDLTA 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENI-----IFGHSG--DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:cd03255   100 LENVelpllLAGVPKkeRRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPKIILADEPTGNLDSETGKEV 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1238650805 171 QEELKRLIAHFGITAFLVSHDLgEVFKLSDEVICLQDGKI 210
Cdd:cd03255   180 MELLRELNKEAGTTIVVVTHDP-ELAEYADRIIELRDGKI 218
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 21-220 1.48e-57

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 184.43  E-value: 1.48e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKgfNLPIQQRKIGFVFQNYALFPHLNVYEN 100
Cdd:COG1126    20 ISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSKK--DINKLRRKVGMVFQQFNLFPHLTVLEN 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFG--HSGDKTR---IEEVMALMELDGLSKKK---ITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:COG1126    98 VTLApiKVKKMSKaeaEERAMELLERVGLADKAdayPAQLSGGQQQRVAIARALAMEPKVMLFDEPTSALDPELVGEVLD 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1238650805 173 ELKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG1126   178 VMRDL-AKEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFF 224
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 21-223 7.96e-57

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 182.49  E-value: 7.96e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQqRKIGFVFQNYALFPHLNVYEN 100
Cdd:COG1127    24 VSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELYELR-RRIGMLFQGGALFDSLTVFEN 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFG---HSG-DKTRIEE-VMALMELDGLS---KKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:COG1127   103 VAFPlreHTDlSEAEIRElVLEKLELVGLPgaaDKMPSELSGGMRKRVALARALALDPEILLYDEPTAGLDPITSAVIDE 182

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 173 ELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSD 223
Cdd:COG1127   183 LIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLASD 233
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 15-220 2.86e-56

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 180.99  E-value: 2.86e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  15 GTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDShkgfNLPIQQRKIGFVFQN--YAL 91
Cdd:COG1122    13 GTPALDdVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKK----NLRELRRKVGLVFQNpdDQL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  92 FpHLNVYENIIFG-----HSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDG 164
Cdd:COG1122    89 F-APTVEEDVAFGpenlgLPREeiRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLDEPTAGLDP 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 165 EMRSKLQEELKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG1122   168 RGRRELLELLKRL-NKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVF 222
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-210 3.81e-56

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 180.62  E-value: 3.81e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIEL-DFEKTL-DGNHGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRivvgnrVYFDSHKGFNLPI 77
Cdd:COG1136     4 LLELrNLTKSYgTGEGEVTALRgVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGE------VLIDGQDISSLSE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  78 QQR------KIGFVFQNYALFPHLNVYENIIF-------GHSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALAR 144
Cdd:COG1136    78 RELarlrrrHIGFVFQFFNLLPELTALENVALplllagvSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIAR 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 145 ALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLgEVFKLSDEVICLQDGKI 210
Cdd:COG1136   158 ALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDP-ELAARADRVIRLRDGRI 222
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
8-228 1.25e-55

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 183.88  E-value: 1.25e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   8 KTLDGNHGtfLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfDSHKGFNLPIQQRKIGFVFQ 87
Cdd:PRK11607   27 KSFDGQHA--VDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIML------DGVDLSHVPPYQRPINMMFQ 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  88 NYALFPHLNVYENIIFGHSGDK-------TRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:PRK11607   99 SYALFPHMTVEQNIAFGLKQDKlpkaeiaSRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMG 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 161 ALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL--SDRFSAK 228
Cdd:PRK11607  179 ALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEhpTTRYSAE 248
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 21-220 7.42e-55

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 177.69  E-value: 7.42e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNR-VYFDSHKGFNlpiqqRKIGFVFQNY--ALFPHLNV 97
Cdd:COG1124    24 VSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRpVTRRRRKAFR-----RRVQMVFQDPyaSLHPRHTV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENI-----IFGHSGDKTRIEEVMALMELD-GLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQ 171
Cdd:COG1124    99 DRILaeplrIHGLPDREERIAELLEQVGLPpSFLDRYPHQLSGGQRQRVAIARALILEPELLLLDEPTSALDVSVQAEIL 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1238650805 172 EELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG1124   179 NLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLL 227
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 21-220 1.35e-54

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 184.34  E-value: 1.35e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVyFDSHKGFNLPIQQRKIGFVFQN--YALFPHLNVY 98
Cdd:COG1123   284 VSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKD-LTKLSRRSLRELRRRVQMVFQDpySSLNPRMTVG 362

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENI-----IFGHSGDKTRIEEVMALMELDGLSKKKIT----ALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSK 169
Cdd:COG1123   363 DIIaeplrLHGLLSRAERRERVAELLERVGLPPDLADryphELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQ 442

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 170 LQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG1123   443 ILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVF 493
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 14-227 1.57e-54

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 177.16  E-value: 1.57e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  14 HGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfDSHKgfnLPIQQ--RKIGFVFQNYA 90
Cdd:COG1120    12 GGRPVLDdVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGR---DLAS---LSRRElaRRIAYVPQEPP 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPHLNVYENIIFG---HSG--------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:COG1120    86 APFGLTVRELVALGrypHLGlfgrpsaeDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLLDEPT 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 160 SALDgeMRSKLQ--EELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSA 227
Cdd:COG1120   166 SHLD--LAHQLEvlELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLTPELLEE 233
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
18-235 3.88e-54

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 179.12  E-value: 3.88e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQQRKIGFVFQNYALFPHLNV 97
Cdd:PRK10851   18 LNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHI------RFHGTDVSRLHARDRKVGFVFQHYALFRHMTV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFGHS-------GDKTRI-EEVMALME---LDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:PRK10851   92 FDNIAFGLTvlprrerPNAAAIkAKVTQLLEmvqLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQV 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 167 RSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL--SDRFSakLQINGEI 235
Cdd:PRK10851  172 RKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWRepATRFV--LEFMGEV 240
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 2-223 1.24e-53

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 174.23  E-value: 1.24e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   2 IEL-DFEKTLDGNHgtFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDSHKGFnLPIQq 79
Cdd:cd03261     1 IELrGLTKSFGGRT--VLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIdGEDISGLSEAEL-YRLR- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  80 RKIGFVFQNYALFPHLNVYENIIFG---HSG-DKTRIEE-VMALMELDGLS---KKKITALSGGQAQRVALARALASSPD 151
Cdd:cd03261    77 RRMGMLFQSGALFDSLTVFENVAFPlreHTRlSEEEIREiVLEKLEAVGLRgaeDLYPAELSGGMKKRVALARALALDPE 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 152 ILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSD 223
Cdd:cd03261   157 LLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRASD 228
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 21-210 1.77e-52

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 170.79  E-value: 1.77e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKgfNLPIQQRKIGFVFQNYALFPHLNVYEN 100
Cdd:cd03262    19 IDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKK--NINELRQKVGMVFQQFNLFPHLTVLEN 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFG-----HSGDKTRIEEVMALMELDGLSKKK---ITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:cd03262    97 ITLApikvkGMSKAEAEERALELLEKVGLADKAdayPAQLSGGQQQRVAIARALAMNPKVMLFDEPTSALDPELVGEVLD 176

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1238650805 173 ELKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:cd03262   177 VMKDL-AEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
1-220 3.69e-52

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 170.32  E-value: 3.69e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELDfekTLDGNHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdSHKGfnLPIQQR 80
Cdd:COG3840     1 MLRLD---DLTYRYGDFPLRFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQ----DLTA--LPPAER 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  81 KIGFVFQNYALFPHLNVYENIIFG-HSG------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDIL 153
Cdd:COG3840    72 PVSMLFQENNLFPHLTVAQNIGLGlRPGlkltaeQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPIL 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 154 LLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG3840   152 LLDEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALL 218
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 13-222 1.80e-51

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 169.02  E-value: 1.80e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  13 NHGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdSHKGFNlPIQ-QRKIGFVFQNYA 90
Cdd:cd03295    11 GGGKKAVNnLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGE----DIREQD-PVElRRKIGYVIQQIG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPHLNVYENI-----IFGHSGDK--TRIEEVMALMELD--GLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSA 161
Cdd:cd03295    86 LFPHMTVEENIalvpkLLKWPKEKirERADELLALVGLDpaEFADRYPHELSGGQQQRVGVARALAADPPLLLMDEPFGA 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 162 LDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLS 222
Cdd:cd03295   166 LDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRS 226
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 21-227 3.17e-51

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 168.34  E-value: 3.17e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGnrvyfdshkGFNLPIQQRKIGFVFQNYAL---FPhLNV 97
Cdd:COG1121    25 VSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLF---------GKPPRRARRRIGYVPQRAEVdwdFP-ITV 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENI---IFGHSG--------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:COG1121    95 RDVVlmgRYGRRGlfrrpsraDREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAAT 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 167 RSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAkRGTPDEVFLSDRFSA 227
Cdd:COG1121   175 EEALYELLRELRRE-GKTILVVTHDLGAVREYFDRVLLLNRGLVA-HGPPEEVLTPENLSR 233
PhnT TIGR03258
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ...
 16-263 1.48e-50

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.


Pssm-ID: 132302 [Multi-domain]  Cd Length: 362  Bit Score: 170.18  E-value: 1.48e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  16 TFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPD--KGRIVVGNRVYfdSHkgfnLPIQQRKIGFVFQNYALFP 93
Cdd:TIGR03258  19 TVLDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFVKAAglTGRIAIADRDL--TH----APPHKRGLALLFQNYALFP 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENIIFGHSGDKT-------RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:TIGR03258  93 HLKVEDNVAFGLRAQKMpkadiaeRVADALKLVGLGDAAAHLPAQLSGGMQQRIAIARAIAIEPDVLLLDEPLSALDANI 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 167 RSKLQEELKRLIAHF-GITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL--SDRFSAKLQINGEIL---KITP 240
Cdd:TIGR03258 173 RANMREEIAALHEELpELTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDapADGFAAEFLGAANILpaiALGI 252

                         250       260
                  ....*....|....*....|...
gi 1238650805 241 QSLITIVDVLSNGSIVRIVLAPS 263
Cdd:TIGR03258 253 TEAPGLVDVSCGGAVIFAFGDGR 275
proV TIGR01186
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...
 20-246 3.49e-50

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130254 [Multi-domain]  Cd Length: 363  Bit Score: 169.26  E-value: 3.49e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRKIGFVFQNYALFPHLNVYE 99
Cdd:TIGR01186  11 DADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMKQSPVELREVRRKKIGMVFQQFALFPHMTILQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:TIGR01186  91 NTSLGpellgwpEQERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSALDPLIRDSMQD 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 173 ELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV-----------FLSDRFSAKLQINGEILKITPQ 241
Cdd:TIGR01186 171 ELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEIlrnpaneyveeFIGKVDLSQVFDAERIAQRMNT 250


                  ....*
gi 1238650805 242 SLITI 246
Cdd:TIGR01186 251 GPITK 255
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 18-220 5.21e-50

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 166.47  E-value: 5.21e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDShKGFNLPIQQRKIGFVFQN--YALFpHL 95
Cdd:TIGR04521  21 LDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAK-KKKKLKDLRKKVGLVFQFpeHQLF-EE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  96 NVYENIIFG-----HSGD--KTRIEEVMALMELD-GLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMR 167
Cdd:TIGR04521  99 TVYKDIAFGpknlgLSEEeaEERVKEALELVGLDeEYLERSPFELSGGQMRRVAIAGVLAMEPEVLILDEPTAGLDPKGR 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 168 SKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:TIGR04521 179 KEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVF 231
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
1-210 9.94e-50

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 163.68  E-value: 9.94e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIEL-DFEKTLDGNHgTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNrvyFDSH--KGFNLPI 77
Cdd:COG2884     1 MIRFeNVSKRYPGGR-EALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNG---QDLSrlKRREIPY 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  78 QQRKIGFVFQNYALFPHLNVYENIIF-----GHSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSP 150
Cdd:COG2884    77 LRRRIGVVFQDFRLLPDRTVYENVALplrvtGKSRKeiRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRP 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 151 DILLLDEPLSALDGEMRSKLQEELKRlIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:COG2884   157 ELLLADEPTGNLDPETSWEIMELLEE-INRRGTTVLIATHDLELVDRMPKRVLELEDGRL 215
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 21-209 4.60e-49

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 161.87  E-value: 4.60e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDShkgfNLPIQQRKIGFVFQN--YALFpHLNVY 98
Cdd:cd03225    20 ISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKL----SLKELRRKVGLVFQNpdDQFF-GPTVE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQ 171
Cdd:cd03225    95 EEVAFGlenlglpEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAGLDPAGRRELL 174

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1238650805 172 EELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGK 209
Cdd:cd03225   175 ELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
13-210 4.80e-49

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 161.52  E-value: 4.80e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  13 NHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYfdshKGFNLPIQQRKIGFVFQNYALF 92
Cdd:COG4619    11 GGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPL----SAMPPPEWRRQVAYVPQEPALW 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  93 PHlNVYENIIF-----GHSGDKTRIEEVMALMELD-GLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:COG4619    87 GG-TVRDNLPFpfqlrERKFDRERALELLERLGLPpDILDKPVERLSGGERQRLALIRALLLQPDVLLLDEPTSALDPEN 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1238650805 167 RSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:COG4619   166 TRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
1-221 9.19e-49

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 164.87  E-value: 9.19e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIEL-DFEKTLDGNHGTF--LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVyFDSHKGFNLPI 77
Cdd:COG1135     1 MIELeNLSKTFPTKGGPVtaLDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVD-LTALSERELRA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  78 QQRKIGFVFQNYALFPHLNVYENIIFG--HSG-DKTRIEE-VMALMELDGLSKKK---ITALSGGQAQRVALARALASSP 150
Cdd:COG1135    80 ARRKIGMIFQHFNLLSSRTVAENVALPleIAGvPKAEIRKrVAELLELVGLSDKAdayPSQLSGGQKQRVGIARALANNP 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 151 DILLLDEPLSALDGEM-RSKLqEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL 221
Cdd:COG1135   160 KVLLCDEATSALDPETtRSIL-DLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFA 230
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 21-219 1.89e-48

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 161.18  E-value: 1.89e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNrvyFDSHKGFNLPiqQRKIGFVFQNYALFPHLNVYEN 100
Cdd:COG4555    20 VSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDG---EDVRKEPREA--RRQIGVLPDERGLYDRLTVREN 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 I-----IFGHSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE 173
Cdd:COG4555    95 IryfaeLYGLFDEelKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNGLDVMARRLLREI 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1238650805 174 LKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:COG4555   175 LRALKKE-GKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDEL 219
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
21-227 3.71e-48

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 164.05  E-value: 3.71e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDshkgfnLPIQQRKIGFVFQNYALFPHLNVYEN 100
Cdd:PRK11000   22 INLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMND------VPPAERGVGMVFQSYALYPHLSVAEN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFG---HSGDKT----RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE 173
Cdd:PRK11000   96 MSFGlklAGAKKEeinqRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMRIE 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 174 LKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL--SDRFSA 227
Cdd:PRK11000  176 ISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHypANRFVA 231
ProV COG4175
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 21-222 1.74e-47

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443334 [Multi-domain]  Cd Length: 389  Bit Score: 162.97  E-value: 1.74e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkgfNLP---------IQQRKIGFVFQNYAL 91
Cdd:COG4175    46 ASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPTAGEVLIDGE---------DITklskkelreLRRKKMSMVFQHFAL 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  92 FPHLNVYENIIFG----HSGDKTRIEEVMALMELDGLS---KKKITALSGGQAQRVALARALASSPDILLLDEPLSALDG 164
Cdd:COG4175   117 LPHRTVLENVAFGleiqGVPKAERRERAREALELVGLAgweDSYPDELSGGMQQRVGLARALATDPDILLMDEAFSALDP 196

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 165 EMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLS 222
Cdd:COG4175   197 LIRREMQDELLELQAKLKKTIVFITHDLDEALRLGDRIAIMKDGRIVQIGTPEEILTN 254
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 12-219 3.08e-47

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 158.11  E-value: 3.08e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  12 GNHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDSHKgfNLPIQQRKIGFVFQNYA 90
Cdd:cd03256    11 PNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIdGTDINKLKGK--ALRQLRRQIGMIFQQFN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPHLNVYENIIFGHSGDK----------TRIEEVMALMELD--GLSKK---KITALSGGQAQRVALARALASSPDILLL 155
Cdd:cd03256    89 LIERLSVLENVLSGRLGRRstwrslfglfPKEEKQRALAALErvGLLDKayqRADQLSGGQQQRVAIARALMQQPKLILA 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1238650805 156 DEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:cd03256   169 DEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAEL 232
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 1-219 5.00e-47

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 157.53  E-value: 5.00e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELD-FEKTLDGnhGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVyFDSHKGFNLPIQ 78
Cdd:COG3638     2 MLELRnLSKRYPG--GTPALDdVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQD-VTALRGRALRRL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  79 QRKIGFVFQNYALFPHLNVYENIIFGHSGDKTR------------IEEVMALMELDGLSKK---KITALSGGQAQRVALA 143
Cdd:COG3638    79 RRRIGMIFQQFNLVPRLSVLTNVLAGRLGRTSTwrsllglfppedRERALEALERVGLADKayqRADQLSGGQQQRVAIA 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 144 RALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:COG3638   159 RALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGRVVFDGPPAEL 234
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 21-214 1.27e-46

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 156.13  E-value: 1.27e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYfDSHKGFNLPIQQRKIGFVFQNY--ALFPHLNVY 98
Cdd:cd03257    24 VSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDL-LKLSRRLRKIRRKEIQMVFQDPmsSLNPRMTIG 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENII------FGHSGDKTRIEEVMALMELDGLSKKKITA----LSGGQAQRVALARALASSPDILLLDEPLSALDGEMRS 168
Cdd:cd03257   103 EQIAeplrihGKLSKKEARKEAVLLLLVGVGLPEEVLNRypheLSGGQRQRVAIARALALNPKLLIADEPTSALDVSVQA 182

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1238650805 169 KLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRG 214
Cdd:cd03257   183 QILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
18-227 4.61e-46

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 155.79  E-value: 4.61e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkgfnlPIQ----QRkiGFVFQNYALFP 93
Cdd:COG4525    23 LQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGV-----------PVTgpgaDR--GVVFQKDALLP 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:COG4525    90 WLNVLDNVAFGlrlrgvpKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLLMDEPFGALDALT 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 167 RSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQD--GKIAKRGTPDevfLSDRFSA 227
Cdd:COG4525   170 REQMQELLLDVWQRTGKGVFLITHSVEEALFLATRLVVMSPgpGRIVERLELD---FSRRFLA 229
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 21-210 2.08e-45

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 151.01  E-value: 2.08e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFnlpiqQRKIGFVFQNYALFPHLNVYEN 100
Cdd:cd03230    19 ISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEV-----KRRIGYLPEEPSLYENLTVREN 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIfghsgdktrieevmalmeldglskkkitaLSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAH 180
Cdd:cd03230    94 LK-----------------------------LSGGMKQRLALAQALLHDPELLILDEPTSGLDPESRREFWELLRELKKE 144

                         170       180       190
                  ....*....|....*....|....*....|
gi 1238650805 181 fGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:cd03230   145 -GKTILLSSHILEEAERLCDRVAILNNGRI 173
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
21-225 1.35e-44

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 151.88  E-value: 1.35e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV------------GNRVYFDSHKgfnlpIQQ--RKIGFVF 86
Cdd:COG4598    27 VSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVggeeirlkpdrdGELVPADRRQ-----LQRirTRLGMVF 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  87 QNYALFPHLNVYENIIFG--HSGDKTR---IEEVMALMELDGLSKKKIT---ALSGGQAQRVALARALASSPDILLLDEP 158
Cdd:COG4598   102 QSFNLWSHMTVLENVIEApvHVLGRPKaeaIERAEALLAKVGLADKRDAypaHLSGGQQQRAAIARALAMEPEVMLFDEP 181

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 159 LSALDGEMrskLQEELK--RLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL---SDRF 225
Cdd:COG4598   182 TSALDPEL---VGEVLKvmRDLAEEGRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGnpkSERL 250
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 18-219 1.72e-44

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 150.41  E-value: 1.72e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGnRVYFDSHKGFNLPIQ----QRKIGFVFQNYALFP 93
Cdd:cd03260    16 LKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIPGAPDEG-EVLLDGKDIYDLDVDvlelRRRVGMVFQKPNPFP 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 hLNVYENIIFG--------HSGDKTRIEEVMALMELDGLSKKKITA--LSGGQAQRVALARALASSPDILLLDEPLSALD 163
Cdd:cd03260    95 -GSIYDNVAYGlrlhgiklKEELDERVEEALRKAALWDEVKDRLHAlgLSGGQQQRLCLARALANEPEVLLLDEPTSALD 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 164 GEMRSKLQEELKRLiaHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:cd03260   174 PISTAKIEELIAEL--KKEYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 21-211 1.92e-44

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 149.99  E-value: 1.92e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfdshKGFNLPIQQRKIGFVFQNYAL---FPhLNV 97
Cdd:cd03235    18 VSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRV---------FGKPLEKERKRIGYVPQRRSIdrdFP-ISV 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENI---IFGHSG--------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:cd03235    88 RDVVlmgLYGHKGlfrrlskaDKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDPKT 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1238650805 167 RSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIA 211
Cdd:cd03235   168 QEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLLNRTVVA 211
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 12-214 4.69e-44

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 147.97  E-value: 4.69e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  12 GNHGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQQ--RKIGFVFQn 88
Cdd:cd03214     8 GYGGRTVLDdLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEI------LLDGKDLASLSPKElaRKIAYVPQ- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  89 yalfphlnvyeniifghsgdktrieeVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRS 168
Cdd:cd03214    81 --------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQI 134

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1238650805 169 KLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRG 214
Cdd:cd03214   135 ELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
8-220 6.34e-44

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 152.69  E-value: 6.34e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   8 KTLDGnhGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDshkgfnLPIQQRKIGFVF 86
Cdd:PRK11650   11 KSYDG--KTQVIKgIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNE------LEPADRDIAMVF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  87 QNYALFPHLNVYENIIFGHSGDKT-------RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:PRK11650   83 QNYALYPHMSVRENMAYGLKIRGMpkaeieeRVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFLFDEPL 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 160 SALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK11650  163 SNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEVY 223
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 21-219 2.84e-43

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 156.92  E-value: 2.84e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDshkgfNLPIQQ-------RKIGFVFQNYALFp 93
Cdd:COG2274   494 ISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRI------LID-----GIDLRQidpaslrRQIGVVLQDVFLF- 561

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENIIFGHSG-DKTRIEEVMALMELDGLSKK-------KI----TALSGGQAQRVALARALASSPDILLLDEPLSA 161
Cdd:COG2274   562 SGTIRENITLGDPDaTDEEIIEAARLAGLHDFIEAlpmgydtVVgeggSNLSGGQRQRLAIARALLRNPRILILDEATSA 641

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 162 LDGEMRSKLQEELKRLIAhfGITAFLVSHDLgEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:COG2274   642 LDAETEAIILENLRRLLK--GRTVIIIAHRL-STIRLADRIIVLDKGRIVEDGTHEEL 696
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 21-219 3.80e-43

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 147.23  E-value: 3.80e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkGFNLPIQQRKIgfVFQNYALFPHLNVYEN 100
Cdd:TIGR01184   4 VNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGK-------QITEPGPDRMV--VFQNYSLLPWLTVREN 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFG---------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQ 171
Cdd:TIGR01184  75 IALAvdrvlpdlsKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQ 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1238650805 172 EELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:TIGR01184 155 EELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQILEV 202
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 21-219 4.20e-43

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 147.20  E-value: 4.20e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRivvgnrVYFDSHKGFNLPIQQRK---IGFVFQNYALFPHLNV 97
Cdd:cd03219    19 VSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGS------VLFDGEDITGLPPHEIArlgIGRTFQIPRLFPELTV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFGHSGDKT-----------------RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:cd03219    93 LENVMVAAQARTGsglllararreereareRAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAA 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805 161 ALDGEMRSKLQEELKRlIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:cd03219   173 GLNPEETEELAELIRE-LRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEV 230
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 21-218 4.82e-43

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 146.75  E-value: 4.82e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGR-IVVGNRVYFDSHKgfnlpiQQRKIGFVFQNYALFPHLNVYE 99
Cdd:cd03265    19 VSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRaTVAGHDVVREPRE------VRRRIGIVFQDLSVDDELTGWE 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NI-----IFGHSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:cd03265    93 NLyiharLYGVPGAerRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDPQTRAHVWE 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1238650805 173 ELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDE 218
Cdd:cd03265   173 YIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEE 218
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 21-220 9.19e-43

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 153.14  E-value: 9.19e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLEnPDKGRIvvGNRVYFDSHKGFNLPIQQR--KIGFVFQN--YALFPhLN 96
Cdd:COG1123    25 VSLTIAPGETVALVGESGSGKSTLALALMGLL-PHGGRI--SGEVLLDGRDLLELSEALRgrRIGMVFQDpmTQLNP-VT 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 VYENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSK 169
Cdd:COG1123   101 VGDQIAEAlenlglsRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEPTTALDVTTQAE 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 170 LQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG1123   181 ILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEIL 231
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 14-210 9.85e-43

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 146.75  E-value: 9.85e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  14 HGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNrvyfdshkgfnLPIQQRK--IGFVFQNYAL 91
Cdd:PRK11247   24 ERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGT-----------APLAEARedTRLMFQDARL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  92 FPHLNVYENIIFGHSGD-KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:PRK11247   93 LPWKKVIDNVGLGLKGQwRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEM 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1238650805 171 QEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:PRK11247  173 QDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 1-221 4.82e-42

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 147.64  E-value: 4.82e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIEL-DFEKTLDGNHGTF--LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNrVYFDSHKGFNLPI 77
Cdd:PRK11153    1 MIELkNISKVFPQGGRTIhaLNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDG-QDLTALSEKELRK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  78 QQRKIGFVFQNYALFPHLNVYENIIF-----GHSGD--KTRIEEvmaLMELDGLSKKKIT---ALSGGQAQRVALARALA 147
Cdd:PRK11153   80 ARRQIGMIFQHFNLLSSRTVFDNVALplelaGTPKAeiKARVTE---LLELVGLSDKADRypaQLSGGQKQRVAIARALA 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1238650805 148 SSPDILLLDEPLSALDGE-MRSKLqEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL 221
Cdd:PRK11153  157 SNPKVLLCDEATSALDPAtTRSIL-ELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFS 230
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 21-219 6.36e-42

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 144.80  E-value: 6.36e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQQR-KIGFV--FQNYALFPHLNV 97
Cdd:COG0411    23 VSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRI------LFDGRDITGLPPHRIaRLGIArtFQNPRLFPELTV 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFG-HSGDKT---------------------RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLL 155
Cdd:COG0411    97 LENVLVAaHARLGRgllaallrlprarreereareRAEELLERVGLADRADEPAGNLSYGQQRRLEIARALATEPKLLLL 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1238650805 156 DEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:COG0411   177 DEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTPAEV 240
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 14-214 8.20e-42

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 143.02  E-value: 8.20e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  14 HGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFdshkgfNLPIQQRKIGFVFQNYALFP 93
Cdd:cd03298    10 YGEQPMHFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVT------AAPPADRPVSMLFQENNLFA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENIIFGHSG-------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:cd03298    84 HLTVEQNVGLGLSPglkltaeDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPAL 163

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1238650805 167 RSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRG 214
Cdd:cd03298   164 RAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 1-219 2.02e-41

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 143.21  E-value: 2.02e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELD-FEKTLDGNHgTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDShKGFNLPIQQ 79
Cdd:TIGR02315   1 MLEVEnLSKVYPNGK-QALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKL-RGKKLRKLR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  80 RKIGFVFQNYALFPHLNVYENIIFGHSGDKTRI------------EEVMALMELDGLSK---KKITALSGGQAQRVALAR 144
Cdd:TIGR02315  79 RRIGMIFQHYNLIERLTVLENVLHGRLGYKPTWrsllgrfseedkERALSALERVGLADkayQRADQLSGGQQQRVAIAR 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1238650805 145 ALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:TIGR02315 159 ALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSEL 233
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 13-209 6.52e-41

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 138.92  E-value: 6.52e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  13 NHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDshkgFNLPIQQRKIGFVFQnyalf 92
Cdd:cd00267    10 GGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAK----LPLEELRRRIGYVPQ----- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  93 phlnvyeniifghsgdktrieevmalmeldglskkkitaLSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:cd00267    81 ---------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRERLLE 121

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1238650805 173 ELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGK 209
Cdd:cd00267   122 LLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
18-215 9.61e-41

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 141.30  E-value: 9.61e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvYFDSHKGFNLPIQQ---RKIGFVFQNYALFPH 94
Cdd:COG4161    18 LFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGH-QFDFSQKPSEKAIRllrQKVGMVFQQYNLWPH 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENII------FGHSGDKTRIE--EVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:COG4161    97 LTVMENLIeapckvLGLSKEQAREKamKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEI 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1238650805 167 RSKLQEELKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGT 215
Cdd:COG4161   177 TAQVVEIIREL-SQTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGD 224
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 18-160 1.85e-40

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 137.78  E-value: 1.85e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdSHKGFNLPIQQRKIGFVFQNYALFPHLNV 97
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQ----DLTDDERKSLRKEIGYVFQDPQLFPRLTV 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1238650805  98 YENIIFG-------HSGDKTRIEEVMALMELDGLSKKKI----TALSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:pfam00005  77 RENLRLGlllkglsKREKDARAEEALEKLGLGDLADRPVgerpGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 21-220 1.94e-40

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 141.41  E-value: 1.94e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHkgfNLPIQQRKIGFVFQNyalfPHlN---- 96
Cdd:TIGR04520  21 VSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLDEE---NLWEIRKKVGMVFQN----PD-Nqfvg 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 --VYENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMR 167
Cdd:TIGR04520  93 atVEDDVAFGlenlgvpREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPDIIILDEATSMLDPKGR 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 168 SKLQEELKRLIAHFGITAFLVSHDLGEVFkLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:TIGR04520 173 KEVLETIRKLNKEEGITVISITHDMEEAV-LADRVIVMNKGKIVAEGTPREIF 224
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 21-209 7.11e-40

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 138.15  E-value: 7.11e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVyFDSHKGFNLPIQQRKIGFVFQNYALFPHLNVYEN 100
Cdd:TIGR02673  21 VSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGED-VNRLRGRQLPLLRRRIGVVFQDFRLLPDRTVYEN 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFGH--SGDKTRI--EEVMALMELDGLSKKKIT---ALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE 173
Cdd:TIGR02673 100 VALPLevRGKKEREiqRRVGAALRQVGLEHKADAfpeQLSGGEQQRVAIARAIVNSPPLLLADEPTGNLDPDLSERILDL 179

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1238650805 174 LKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGK 209
Cdd:TIGR02673 180 LKRLNKR-GTTVIVATHDLSLVDRVAHRVIILDDGR 214
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 15-218 2.05e-39

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 144.52  E-value: 2.05e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  15 GTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdSHKGFNLPIQQRKIGFVFQNYALFp 93
Cdd:COG4988   349 GRPALDgLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGV----DLSDLDPASWRRQIAWVPQNPYLF- 423

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENIIFGHSG-DKTRIEEVMALMELDGLSKK-------KI----TALSGGQAQRVALARALASSPDILLLDEPLSA 161
Cdd:COG4988   424 AGTIRENLRLGRPDaSDEELEAALEAAGLDEFVAAlpdgldtPLgeggRGLSGGQAQRLALARALLRDAPLLLLDEPTAH 503

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 162 LDGEMRSKLQEELKRLIAhfGITAFLVSHDLGEVfKLSDEVICLQDGKIAKRGTPDE 218
Cdd:COG4988   504 LDAETEAEILQALRRLAK--GRTVILITHRLALL-AQADRILVLDDGRIVEQGTHEE 557
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 21-209 2.15e-39

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 135.59  E-value: 2.15e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdSHKGFNLPIQQRKIGFVFQNYALFpHLNVYEN 100
Cdd:cd03228    21 VSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGV----DLRDLDLESLRKNIAYVPQDPFLF-SGTIREN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IifghsgdktrieevmalmeldglskkkitaLSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAh 180
Cdd:cd03228    96 I------------------------------LSGGQRQRIAIARALLRDPPILILDEATSALDPETEALILEALRALAK- 144

                         170       180
                  ....*....|....*....|....*....
gi 1238650805 181 fGITAFLVSHDLgEVFKLSDEVICLQDGK 209
Cdd:cd03228   145 -GKTVIVIAHRL-STIRDADRIIVLDDGR 171
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 13-195 2.21e-39

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 136.84  E-value: 2.21e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  13 NHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDkgrIVVGNRVYFDSHKGFNLPIQQRKIGFVFQNYALF 92
Cdd:COG4136    12 GGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPA---FSASGEVLLNGRRLTALPAEQRRIGILFQDDLLF 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  93 PHLNVYENIIFG------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:COG4136    89 PHLSVGENLAFAlpptigRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAAL 168

                         170       180
                  ....*....|....*....|....*....
gi 1238650805 167 RSKLQEELKRLIAHFGITAFLVSHDLGEV 195
Cdd:COG4136   169 RAQFREFVFEQIRQRGIPALLVTHDEEDA 197
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 1-210 3.26e-39

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 137.18  E-value: 3.26e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELD-FEKTLDGNHG--TFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfDSHKGFNLPI 77
Cdd:COG4181     8 IIELRgLTKTVGTGAGelTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRL------AGQDLFALDE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  78 QQR------KIGFVFQNYALFPHLNVYENI-----IFGHSGDKTRIEEVMALMeldGLSKKkITA----LSGGQAQRVAL 142
Cdd:COG4181    82 DARarlrarHVGFVFQSFQLLPTLTALENVmlpleLAGRRDARARARALLERV---GLGHR-LDHypaqLSGGEQQRVAL 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 143 ARALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLgEVFKLSDEVICLQDGKI 210
Cdd:COG4181   158 ARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDP-ALAARCDRVLRLRAGRL 224
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 21-209 3.82e-39

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 136.07  E-value: 3.82e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFnlpiqQRKIGFVFQNYALFPHLNVYEN 100
Cdd:COG4133    21 LSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDY-----RRRLAYLGHADGLKPELTVREN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIF-----GHSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELK 175
Cdd:COG4133    96 LRFwaalyGLRADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALDAAGVALLAELIA 175

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1238650805 176 RLIAHFGItAFLVSHDLGEVfkLSDEVICLQDGK 209
Cdd:COG4133   176 AHLARGGA-VLLTTHQPLEL--AAARVLDLGDFK 206
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 21-205 4.50e-39

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 135.82  E-value: 4.50e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRKIGFVFQNYALFPHLNVYEN 100
Cdd:TIGR03608  17 LNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASKFRREKLGYLFQNFALIENETVEEN 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFGHSGDK-------TRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE 173
Cdd:TIGR03608  97 LDLGLKYKKlskkekrEKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADEPTGSLDPKNRDEVLDL 176

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1238650805 174 LKRLiAHFGITAFLVSHDLgEVFKLSDEVICL 205
Cdd:TIGR03608 177 LLEL-NDEGKTIIIVTHDP-EVAKQADRVIEL 206
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 1-214 1.08e-38

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 135.19  E-value: 1.08e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELD-FEKTLDGNHGTFLL--QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNrvyFDSHKGfnlPI 77
Cdd:cd03266     1 MITADaLTKRFRDVKKTVQAvdGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDG---FDVVKE---PA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  78 Q-QRKIGFVFQNYALFPHLNVYENIIF-----GHSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASS 149
Cdd:cd03266    75 EaRRRLGFVSDSTGLYDRLTARENLEYfaglyGLKGDelTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHD 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1238650805 150 PDILLLDEPLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRG 214
Cdd:cd03266   155 PPVLLLDEPTTGLDVMATRALREFIRQLRAL-GKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
1-230 1.62e-38

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 135.61  E-value: 1.62e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELdfeKTLDGNHG--TFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLpIQ 78
Cdd:PRK09493    1 MIEF---KNVSKHFGptQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERL-IR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  79 QrKIGFVFQNYALFPHLNVYENIIFG----HSGDKTRIEEV-MALMELDGLSKKK---ITALSGGQAQRVALARALASSP 150
Cdd:PRK09493   77 Q-EAGMVFQQFYLFPHLTALENVMFGplrvRGASKEEAEKQaRELLAKVGLAERAhhyPSELSGGQQQRVAIARALAVKP 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 151 DILLLDEPLSALDGEMRsklQEELK--RLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVfLSDRFSAK 228
Cdd:PRK09493  156 KLMLFDEPTSALDPELR---HEVLKvmQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVL-IKNPPSQR 231


                  ..
gi 1238650805 229 LQ 230
Cdd:PRK09493  232 LQ 233
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 14-214 3.94e-38

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 133.50  E-value: 3.94e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  14 HGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFnlpiqqRKIGFVFQNYALFP 93
Cdd:cd03268    12 KKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEAL------RRIGALIEAPGFYP 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENIIF---GHSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:cd03268    86 NLTARENLRLlarLLGIRKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLDPDGIKEL 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1238650805 171 QEELKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRG 214
Cdd:cd03268   166 RELILSL-RDQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 18-217 5.30e-38

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 134.37  E-value: 5.30e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvYFD-SHKGFNLPIQQ--RKIGFVFQNYALFPH 94
Cdd:PRK11124   18 LFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGN-HFDfSKTPSDKAIRElrRNVGMVFQQYNLWPH 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENII------FGHSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:PRK11124   97 LTVQQNLIeapcrvLGLSKDqaLARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEI 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 167 RSKLQEELKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPD 217
Cdd:PRK11124  177 TAQIVSIIREL-AETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDAS 226
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 1-220 5.93e-38

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 134.49  E-value: 5.93e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIEL-DFEKTLDGNhgTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNrVYFDSHKGFNLpiQQ 79
Cdd:PRK11264    3 AIEVkNLVKKFHGQ--TVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGD-ITIDTARSLSQ--QK 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  80 RKI-------GFVFQNYALFPHLNVYENIIFG--------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALAR 144
Cdd:PRK11264   78 GLIrqlrqhvGFVFQNFNLFPHRTVLENIIEGpvivkgepKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIAR 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 145 ALASSPDILLLDEPLSALDGEMRSKLQEELKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK11264  158 ALAMRPEVILFDEPTSALDPELVGEVLNTIRQL-AQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALF 232
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
21-218 6.96e-38

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 140.69  E-value: 6.96e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkgfnlPIQQ-------RKIGFVFQNYALFp 93
Cdd:COG1132   359 ISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGV-----------DIRDltleslrRQIGVVPQDTFLF- 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENIIFGHSG-DKTRIEEVMALMELDGLskkkITA---------------LSGGQAQRVALARALASSPDILLLDE 157
Cdd:COG1132   427 SGTIRENIRYGRPDaTDEEVEEAAKAAQAHEF----IEAlpdgydtvvgergvnLSGGQRQRIAIARALLKDPPILILDE 502

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 158 PLSALDGEMRSKLQEELKRLIAhfGITAFLVSHDLGEVfKLSDEVICLQDGKIAKRGTPDE 218
Cdd:COG1132   503 ATSALDTETEALIQEALERLMK--GRTTIVIAHRLSTI-RNADRILVLDDGRIVEQGTHEE 560
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 21-210 7.48e-38

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 132.92  E-value: 7.48e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgNRVYFDSHKGFNLPIQQRKIGFVFQNYALFPHLNVYEN 100
Cdd:cd03292    20 INISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRV-NGQDVSDLRGRAIPYLRRKIGVVFQDFRLLPDRNVYEN 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIF-----GHSGDKTRiEEVMALMELDGLSKKKIT---ALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:cd03292    99 VAFalevtGVPPREIR-KRVPAALELVGLSHKHRAlpaELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTTWEIMN 177

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1238650805 173 ELKRlIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:cd03292   178 LLKK-INKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 11-210 8.94e-38

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 132.38  E-value: 8.94e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  11 DGNHGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVyfdshkgFNLPIQQRKIGFVFQN- 88
Cdd:cd03226     8 SYKKGTEILDdLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKP-------IKAKERRKSIGYVMQDv 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  89 -YALFPHlNVYENIIFGH---SGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDG 164
Cdd:cd03226    81 dYQLFTD-SVREELLLGLkelDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDY 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1238650805 165 EMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:cd03226   160 KNMERVGELIRELAAQ-GKAVIVITHDYEFLAKVCDRVLLLANGAI 204
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 21-219 1.95e-37

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 132.17  E-value: 1.95e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNR--VYFDSHKgfnlpIQQRKIGFVFQNYALFPHLNVY 98
Cdd:cd03224    19 VSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRdiTGLPPHE-----RARAGIGYVPEGRRIFPELTVE 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENIIFG-----HSGDKTRIEEVMALM-ELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:cd03224    94 ENLLLGayarrRAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPKIVEEIFE 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1238650805 173 ELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:cd03224   174 AIRELRDE-GVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAEL 219
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
18-227 5.53e-37

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 131.75  E-value: 5.53e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVyfdshKGfnlPIQQRkiGFVFQNYALFPHLN 96
Cdd:PRK11248   17 LEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLdGKPV-----EG---PGAER--GVVFQNEGLLPWRN 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 VYENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSK 169
Cdd:PRK11248   87 VQDNVAFGlqlagveKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQ 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 170 LQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQ--DGKIAKRGTPDevfLSDRFSA 227
Cdd:PRK11248  167 MQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSpgPGRVVERLPLN---FARRFVA 223
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
22-220 1.67e-36

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 134.39  E-value: 1.67e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  22 SLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRKIGFVFQNYALFPHLNVYENI 101
Cdd:PRK10070   48 SLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKIAMVFQSFALMPHMTVLDNT 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 102 IFGH-----SGDKTRIEEVMALME--LDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEEL 174
Cdd:PRK10070  128 AFGMelagiNAEERREKALDALRQvgLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDEL 207

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1238650805 175 KRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK10070  208 VKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEIL 253
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
21-230 4.43e-36

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 129.70  E-value: 4.43e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRV------------YFDSHKgfnLPIQQRKIGFVFQN 88
Cdd:PRK10619   24 VSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTinlvrdkdgqlkVADKNQ---LRLLRTRLTMVFQH 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  89 YALFPHLNVYENII--------FGHSGDKTRIEEVMALMELDGLSKKKITA-LSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:PRK10619  101 FNLWSHMTVLENVMeapiqvlgLSKQEARERAVKYLAKVGIDERAQGKYPVhLSGGQQQRVSIARALAMEPEVLLFDEPT 180

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 160 SALDGEMRSKLQEELKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRfSAKLQ 230
Cdd:PRK10619  181 SALDPELVGEVLRIMQQL-AEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQ-SPRLQ 249
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 20-218 1.16e-35

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 127.24  E-value: 1.16e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDSHKgfnlpiQQRKIGFVFQNYALFPHLNVY 98
Cdd:cd03263    20 DLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYInGYSIRTDRKA------ARQSLGYCPQFDALFDELTVR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENIIF-----GHSgDKTRIEEVMALMELDGLSK---KKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:cd03263    94 EHLRFyarlkGLP-KSEIKEEVELLLRVLGLTDkanKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGLDPASRRAI 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1238650805 171 QEELKRLIAhfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDE 218
Cdd:cd03263   173 WDLILEVRK--GRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQE 218
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 18-220 2.87e-35

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 128.21  E-value: 2.87e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRKIGFVFQnyalFPHLNV 97
Cdd:PRK13634   23 LYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKKNKKLKPLRKKVGIVFQ----FPEHQL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENII----------FGHSGDKTRiEEVMALMELDGLSKKKIT----ALSGGQAQRVALARALASSPDILLLDEPLSALD 163
Cdd:PRK13634   99 FEETVekdicfgpmnFGVSEEDAK-QKAREMIELVGLPEELLArspfELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLD 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 164 GEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK13634  178 PKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIF 234
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
21-219 5.36e-35

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 131.68  E-value: 5.36e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDShkgfnlPI--QQRKIGFVFQNYALFPHLNV 97
Cdd:COG1129    23 VSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLdGEPVRFRS------PRdaQAAGIAIIHQELNLVPNLSV 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFGH----SG--DKTRI----EEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMR 167
Cdd:COG1129    97 AENIFLGReprrGGliDWRAMrrraRELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRDARVLILDEPTASLTEREV 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 168 SKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:COG1129   177 ERLFRIIRRLKAQ-GVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPVAEL 227
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 1-237 1.43e-34

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 125.58  E-value: 1.43e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELD-FEKTLDGNhgTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDShkgfnlPIQQ 79
Cdd:COG4604     1 MIEIKnVSKRYGGK--VVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATT------PSRE 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  80 --RKIGFVFQNYALFPHLNVYENIIFG---HSG------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALAS 148
Cdd:COG4604    73 laKRLAILRQENHINSRLTVRELVAFGrfpYSKgrltaeDREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQ 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 149 SPDILLLDEPLSALDgeMRSKLQ--EELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVflsdrfs 226
Cdd:COG4604   153 DTDYVLLDEPLNNLD--MKHSVQmmKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEI------- 223

                         250
                  ....*....|.
gi 1238650805 227 aklqINGEILK 237
Cdd:COG4604   224 ----ITPEVLS 230
cbiO PRK13637
energy-coupling factor transporter ATPase;
21-220 1.50e-34

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 126.32  E-value: 1.50e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNrvyFD-SHKGFNLPIQQRKIGFVFQ--NYALFPHlNV 97
Cdd:PRK13637   26 VNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDG---VDiTDKKVKLSDIRKKVGLVFQypEYQLFEE-TI 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFGHSG-------DKTRIEEVMALMELD--GLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRS 168
Cdd:PRK13637  102 EKDIAFGPINlglseeeIENRVKRAMNIVGLDyeDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRD 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 169 KLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK13637  182 EILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVF 233
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 21-220 2.11e-34

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 126.71  E-value: 2.11e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPdkgRIVVGNRVYFD-------SHKGFNlPIQQRKIGFVFQN-Y-AL 91
Cdd:COG0444    24 VSFDVRRGETLGLVGESGSGKSTLARAILGLLPP---PGITSGEILFDgedllklSEKELR-KIRGREIQMIFQDpMtSL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  92 FPHLNVYENI-----IFGHSGDKTRIEEVMALMELDGLSKKKITA------LSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:COG0444   100 NPVMTVGDQIaeplrIHGGLSKAEARERAIELLERVGLPDPERRLdrypheLSGGMRQRVMIARALALEPKLLIADEPTT 179

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 161 ALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG0444   180 ALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELF 239
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 21-220 3.26e-34

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 126.38  E-value: 3.26e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVvgnrvyFDSHKGFNLPIQQ-----RKIGFVFQN-YA-LFP 93
Cdd:COG4608    37 VSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEIL------FDGQDITGLSGRElrplrRRMQMVFQDpYAsLNP 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENI-----IFGHSGDKTRIEEVMALMELDGLSKKKIT----ALSGGQAQRVALARALASSPDILLLDEPLSALDG 164
Cdd:COG4608   111 RMTVGDIIaeplrIHGLASKAERRERVAELLELVGLRPEHADryphEFSGGQRQRIGIARALALNPKLIVCDEPVSALDV 190

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 165 EMRSK-------LQEElkrliahFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG4608   191 SIQAQvlnlledLQDE-------LGLTYLFISHDLSVVRHISDRVAVMYLGKIVEIAPRDELY 246
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 13-214 3.30e-34

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 123.43  E-value: 3.30e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  13 NHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdSHKGfnLPIQQRKIGFVFQNYALF 92
Cdd:TIGR01277   9 EYEHLPMEFDLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQ----SHTG--LAPYQRPVSMLFQENNLF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  93 PHLNVYENIIFG-HSG------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGE 165
Cdd:TIGR01277  83 AHLTVRQNIGLGlHPGlklnaeQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPL 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1238650805 166 MRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRG 214
Cdd:TIGR01277 163 LREEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 12-218 3.76e-34

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 123.88  E-value: 3.76e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  12 GNHGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfDSH--KGFNLPIQQRKIGFVFQN 88
Cdd:cd03251    11 PGDGPPVLRdISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILI------DGHdvRDYTLASLRRQIGLVSQD 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  89 YALFpHLNVYENIIFGHSgDKTRiEEVMA----------LMELDGLSKKKI----TALSGGQAQRVALARALASSPDILL 154
Cdd:cd03251    85 VFLF-NDTVAENIAYGRP-GATR-EEVEEaaraanahefIMELPEGYDTVIgergVKLSGGQRQRIAIARALLKDPPILI 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1238650805 155 LDEPLSALDGEMRSKLQEELKRLIAhfGITAFLVSHDLGEVfKLSDEVICLQDGKIAKRGTPDE 218
Cdd:cd03251   162 LDEATSALDTESERLVQAALERLMK--NRTTFVIAHRLSTI-ENADRIVVLEDGKIVERGTHEE 222
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
19-218 4.87e-34

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 123.54  E-value: 4.87e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  19 LQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDShkgfnlPIQQRKIGFVFQNYALFPHLNVY 98
Cdd:PRK10771   16 MRFDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTT------PPSRRPVSMLFQENNLFSHLTVA 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENIIFG-HSG------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQ 171
Cdd:PRK10771   90 QNIGLGlNPGlklnaaQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEML 169

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1238650805 172 EELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDE 218
Cdd:PRK10771  170 TLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDE 216
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
21-222 5.63e-34

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 124.18  E-value: 5.63e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQQR--KIGFVFQ--NYALFPHLN 96
Cdd:COG4167    32 VSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEI------LINGHKLEYGDYKYRckHIRMIFQdpNTSLNPRLN 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 VyeniifGHSGD-----------KTRIEEVMALMELDGLSKK----KITALSGGQAQRVALARALASSPDILLLDEPLSA 161
Cdd:COG4167   106 I------GQILEeplrlntdltaEEREERIFATLRLVGLLPEhanfYPHMLSSGQKQRVALARALILQPKIIIADEALAA 179

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 162 LDGEMRS-------KLQEELkrliahfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLS 222
Cdd:COG4167   180 LDMSVRSqiinlmlELQEKL-------GISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEVFAN 240
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
20-219 6.76e-34

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 124.11  E-value: 6.76e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDshkGFNLPIQQR--------KIGFVFQNYAL 91
Cdd:PRK11831   25 NISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEI------LFD---GENIPAMSRsrlytvrkRMSMLFQSGAL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  92 FPHLNVYENIIFGHSgDKTRIEE------VMALME---LDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSAL 162
Cdd:PRK11831   96 FTDMNVFDNVAYPLR-EHTQLPApllhstVMMKLEavgLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQ 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 163 DGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:PRK11831  175 DPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL 231
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
20-232 7.92e-34

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 123.69  E-value: 7.92e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkgfnlPIQQ-------RKIGFVFQNYAL- 91
Cdd:COG4559    19 DVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGR-----------PLAAwspwelaRRRAVLPQHSSLa 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  92 FPhLNVYENIIFGHSG-------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALA-------SSPDILLLDE 157
Cdd:COG4559    88 FP-FTVEEVVALGRAPhgssaaqDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAqlwepvdGGPRWLFLDE 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 158 PLSALDgemrskL--QEELKRLIAHF---GITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF----LSDRFSAK 228
Cdd:COG4559   167 PTSALD------LahQHAVLRLARQLarrGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEEVLtdelLERVYGAD 240


                  ....
gi 1238650805 229 LQIN 232
Cdd:COG4559   241 LRVL 244
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
18-220 9.14e-34

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 123.97  E-value: 9.14e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGnrvyfdshkGFNLPIQ-----QRKIGFVFQNY-AL 91
Cdd:PRK13635   23 LKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVG---------GMVLSEEtvwdvRRQVGMVFQNPdNQ 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  92 FPHLNVYENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDG 164
Cdd:PRK13635   94 FVGATVQDDVAFGlenigvpREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDP 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 165 EMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKlSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK13635  174 RGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIF 228
cbiO PRK13650
energy-coupling factor transporter ATPase;
18-220 9.37e-34

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 124.07  E-value: 9.37e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDshkgfNLPIQQRKIGFVFQNY-ALFPHL 95
Cdd:PRK13650   23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIdGDLLTEE-----NVWDIRHKIGMVFQNPdNQFVGA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  96 NVYENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRS 168
Cdd:PRK13650   98 TVEDDVAFGlenkgipHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRL 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 169 KLQEELKRLIAHFGITAFLVSHDLGEVfKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK13650  178 ELIKTIKGIRDDYQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPRELF 228
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 15-227 1.94e-33

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 122.50  E-value: 1.94e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  15 GTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPdkgriVVGNRVY-FDSHKG----FNLpiqQRKIGFV--- 85
Cdd:COG1119    15 GKTILDdISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPP-----TYGNDVRlFGERRGgedvWEL---RKRIGLVspa 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  86 FQNYaLFPHLNVYENII---FGHSG--------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILL 154
Cdd:COG1119    87 LQLR-FPRDETVLDVVLsgfFDSIGlyreptdeQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDPELLI 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 155 LDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSA 227
Cdd:COG1119   166 LDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEVLTSENLSE 238
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 21-218 4.00e-33

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 121.11  E-value: 4.00e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNrvyfDSHKGFNLPIQQRKIGFVFQNYALFPhLNVYEN 100
Cdd:cd03249    22 LSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDG----VDIRDLNLRWLRSQIGLVSQEPVLFD-GTIAEN 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFG-HSGDKTRIEE----------VMALME-LDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRS 168
Cdd:cd03249    97 IRYGkPDATDEEVEEaakkanihdfIMSLPDgYDTLVGERGSQLSGGQKQRIAIARALLRNPKILLLDEATSALDAESEK 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1238650805 169 KLQEELKRLIAhfGITAFLVSHDLGEVfKLSDEVICLQDGKIAKRGTPDE 218
Cdd:cd03249   177 LVQEALDRAMK--GRTTIVIAHRLSTI-RNADLIAVLQNGQVVEQGTHDE 223
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 21-223 1.27e-32

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 119.64  E-value: 1.27e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfDSHKgfnLPIQQ--RKIGFVFQNYALFPHlNVY 98
Cdd:cd03254    22 INFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGI---DIRD---ISRKSlrSMIGVVLQDTFLFSG-TIM 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENIIFGHSG-DKTRIEEVMALMELDGLSKKKI-----------TALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:cd03254    95 ENIRLGRPNaTDEEVIEAAKEAGAHDFIMKLPngydtvlgengGNLSQGERQLLAIARAMLRDPKILILDEATSNIDTET 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 167 RSKLQEELKRLIAhfGITAFLVSHDLGEVfKLSDEVICLQDGKIAKRGTPDEVFLSD 223
Cdd:cd03254   175 EKLIQEALEKLMK--GRTSIIIAHRLSTI-KNADKILVLDDGKIIEEGTHDELLAKK 228
cbiO PRK13646
energy-coupling factor transporter ATPase;
21-231 1.56e-32

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 121.04  E-value: 1.56e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGN-RVYFDSHKGFNLPIQQRkIGFVFQnyalFPHLNVYE 99
Cdd:PRK13646   26 VNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDiTITHKTKDKYIRPVRKR-IGMVFQ----FPESQLFE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 N-----IIFGHSGDKTRIEEVMA-----LMELdGLSKKKITA----LSGGQAQRVALARALASSPDILLLDEPLSALDGE 165
Cdd:PRK13646  101 DtvereIIFGPKNFKMNLDEVKNyahrlLMDL-GFSRDVMSQspfqMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLDPQ 179

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 166 MRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSAKLQI 231
Cdd:PRK13646  180 SKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKKKLADWHI 245
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 21-219 1.60e-32

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 124.75  E-value: 1.60e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDShkgfnlPIQQRK--IGFVFQNYALFPHLNV 97
Cdd:COG3845    24 VSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIdGKPVRIRS------PRDAIAlgIGMVHQHFMLVPNLTV 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFGHSGDKTRI-------EEVMALMELDGLS---KKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMR 167
Cdd:COG3845    98 AENIVLGLEPTKGGRldrkaarARIRELSERYGLDvdpDAKVEDLSVGEQQRVEILKALYRGARILILDEPTAVLTPQEA 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 168 SKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:COG3845   178 DELFEILRRLAAE-GKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDTAET 228
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 21-218 1.90e-32

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 119.64  E-value: 1.90e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSH--KGFNLPIQQRKIGFVFQNYALFpHLNVY 98
Cdd:cd03253    20 VSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSI------LIDGQdiREVTLDSLRRAIGVVPQDTVLF-NDTIG 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENIIFGHSG----------DKTRIEEVMALMElDGLSKK---KITALSGGQAQRVALARALASSPDILLLDEPLSALDGE 165
Cdd:cd03253    93 YNIRYGRPDatdeevieaaKAAQIHDKIMRFP-DGYDTIvgeRGLKLSGGEKQRVAIARAILKNPPILLLDEATSALDTH 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 166 MRSKLQEELKRLIAhfGITAFLVSHDLGEVFKlSDEVICLQDGKIAKRGTPDE 218
Cdd:cd03253   172 TEREIQAALRDVSK--GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTHEE 221
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 21-211 4.45e-32

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 116.37  E-value: 4.45e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDShkgfnlPI--QQRKIGFVFQnyalfphlnv 97
Cdd:cd03216    19 VSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVdGKEVSFAS------PRdaRRAGIAMVYQ---------- 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 yeniifghsgdktrieevmalmeldglskkkitaLSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKRL 177
Cdd:cd03216    83 ----------------------------------LSVGERQMVEIARALARNARLLILDEPTAALTPAEVERLFKVIRRL 128

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1238650805 178 IAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIA 211
Cdd:cd03216   129 RAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
cbiO PRK13641
energy-coupling factor transporter ATPase;
18-252 4.78e-32

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 119.93  E-value: 4.78e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRKIGFVFQnyalFPHLNV 97
Cdd:PRK13641   23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGNKNLKKLRKKVSLVFQ----FPEAQL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENII----------FGHSGDKTRIEEVMALMELdGLSKKKITA----LSGGQAQRVALARALASSPDILLLDEPLSALD 163
Cdd:PRK13641   99 FENTVlkdvefgpknFGFSEDEAKEKALKWLKKV-GLSEDLISKspfeLSGGQMRRVAIAGVMAYEPEILCLDEPAAGLD 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 164 GEMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF--------------LSDRFSAKL 229
Cdd:PRK13641  178 PEGRKEMMQLFKDYQKA-GHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFsdkewlkkhyldepATSRFASKL 256

                         250       260
                  ....*....|....*....|...
gi 1238650805 230 QINGEILKITPQSLITIVDVLSN 252
Cdd:PRK13641  257 EKGGFKFSEMPLTIDELVDGIKN 279
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 18-220 9.80e-32

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 118.70  E-value: 9.80e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVyFDSHkgfNLPIQQRKIGFVFQN--------- 88
Cdd:PRK13648   25 LKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQA-ITDD---NFEKLRKHIGIVFQNpdnqfvgsi 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  89 ------YALFPHLNVYENIifghsgdKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSAL 162
Cdd:PRK13648  101 vkydvaFGLENHAVPYDEM-------HRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSML 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 163 DGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKlSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK13648  174 DPDARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIF 230
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 21-210 1.14e-31

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 117.43  E-value: 1.14e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFnlpiqQRKIGFVF-QNYALFPHLNVYE 99
Cdd:cd03267    40 ISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRRKKF-----LRRIGVVFgQKTQLWWDLPVID 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NI-----IFGHSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:cd03267   115 SFyllaaIYDLPPArfKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRN 194

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1238650805 173 ELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:cd03267   195 FLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRL 232
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 21-220 9.19e-31

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 114.95  E-value: 9.19e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQQRK---IGFVFQNYALFPHLNV 97
Cdd:cd03218    19 VSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKI------LLDGQDITKLPMHKRArlgIGYLPQEASIFRKLTV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENI-----IFGHSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDgemrSKL 170
Cdd:cd03218    93 EENIlavleIRGLSKKerEEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEPFAGVD----PIA 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 171 QEELKRLIAH---FGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:cd03218   169 VQDIQKIIKIlkdRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIA 221
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 21-231 1.28e-30

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 115.47  E-value: 1.28e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDshkgfNLPIQQRKIGFVFQNY-ALFPHLNVY 98
Cdd:PRK13632   28 VSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIdGITISKE-----NLKEIRKKIGIIFQNPdNQFIGATVE 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQ 171
Cdd:PRK13632  103 DDIAFGlenkkvpPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREIK 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 172 EELKRLIAHFGITAFLVSHDLGEVFkLSDEVICLQDGKIAKRGTPDEVFLSDRFSAKLQI 231
Cdd:PRK13632  183 KIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKLIAQGKPKEILNNKEILEKAKI 241
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 21-219 1.78e-30

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 114.31  E-value: 1.78e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNR--VYFDSHKgfnlpIQQRKIGFVFQNYALFPHLNVY 98
Cdd:COG0410    22 VSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEdiTGLPPHR-----IARLGIGYVPEGRRIFPSLTVE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENIIFG------HSGDKTRIEEVMALM-ELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEP---LSALdgeMRS 168
Cdd:COG0410    97 ENLLLGayarrdRAEVRADLERVYELFpRLKERRRQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPslgLAPL---IVE 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 169 KLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:COG0410   174 EIFEIIRRLNRE-GVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAEL 223
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 18-230 1.84e-30

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 114.51  E-value: 1.84e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfdshKGFNLPIQ-----QRKIGFVFQNYALF 92
Cdd:cd03252    18 LDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLV---------DGHDLALAdpawlRRQVGVVLQENVLF 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  93 pHLNVYENIIFGHSG-DKTRIEEVMAL-------MEL----DGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:cd03252    89 -NRSIRDNIALADPGmSMERVIEAAKLagahdfiSELpegyDTIVGEQGAGLSGGQRQRIAIARALIHNPRILIFDEATS 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 161 ALDGEMRSKLQEELKRLIAhfGITAFLVSHDLGEVfKLSDEVICLQDGKIAKRGTPDEVFLSDRFSAKLQ 230
Cdd:cd03252   168 ALDYESEHAIMRNMHDICA--GRTVIIIAHRLSTV-KNADRIIVMEKGRIVEQGSHDELLAENGLYAYLY 234
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 20-232 2.44e-30

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 114.48  E-value: 2.44e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkgfnlPIQQ-------RKIGFVFQNYAL- 91
Cdd:PRK13548   20 DVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGR-----------PLADwspaelaRRRAVLPQHSSLs 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  92 FPhLNVYENIIFG---HSGDKTR----IEEVMALMELDGLSKKKITALSGGQAQRVALARALA------SSPDILLLDEP 158
Cdd:PRK13548   89 FP-FTVEEVVAMGrapHGLSRAEddalVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdGPPRWLLLDEP 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 159 LSALDgemrskL--QEELKRLIAHF----GITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF----LSDRFSAK 228
Cdd:PRK13548  168 TSALD------LahQHHVLRLARQLaherGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAEVLtpetLRRVYGAD 241


                  ....
gi 1238650805 229 LQIN 232
Cdd:PRK13548  242 VLVQ 245
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 18-214 3.45e-30

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 112.67  E-value: 3.45e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGkFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQ-QRKIGFVFQNYALFPHLN 96
Cdd:cd03264    16 LDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTI------RIDGQDVLKQPQKlRRRIGYLPQEFGVYPNFT 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 VYENIIF-------GHSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSK 169
Cdd:cd03264    89 VREFLDYiawlkgiPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLDPEERIR 168

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1238650805 170 LQEELKRLIAhfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRG 214
Cdd:cd03264   169 FRNLLSELGE--DRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 21-218 3.48e-30

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 119.10  E-value: 3.48e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkgfnlPIQQ-------RKIGFVFQNYALFp 93
Cdd:COG4987   354 LSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGV-----------DLRDldeddlrRRIAVVPQRPHLF- 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENIIFGhSGDKTRiEEVMALMELDGLSK------KKI--------TALSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:COG4987   422 DTTLRENLRLA-RPDATD-EELWAALERVGLGDwlaalpDGLdtwlgeggRRLSGGERRRLALARALLRDAPILLLDEPT 499

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805 160 SALDGEMRSKLQEELKRLIAhfGITAFLVSHDLgEVFKLSDEVICLQDGKIAKRGTPDE 218
Cdd:COG4987   500 EGLDAATEQALLADLLEALA--GRTVLLITHRL-AGLERMDRILVLEDGRIVEQGTHEE 555
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 21-219 4.52e-30

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 113.25  E-value: 4.52e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFdshkgfnlPIQqrkIGFVFQnyalfPHLNVYEN 100
Cdd:COG1134    45 VSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRVSA--------LLE---LGAGFH-----PELTGREN 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIF-----GHSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE 173
Cdd:COG1134   109 IYLngrllGLSRKeiDEKFDEIVEFAELGDFIDQPVKTYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLAR 188

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1238650805 174 LKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:COG1134   189 IRELRES-GRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEV 233
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 21-220 5.27e-30

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 118.25  E-value: 5.27e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLEnPDKGRIVV-GNRVyfDSHKGFNLPIQQRKIGFVFQN-YA-LFPHLNV 97
Cdd:COG4172   305 VSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFdGQDL--DGLSRRALRPLRRRMQVVFQDpFGsLSPRMTV 381

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 yENII-------FGHSGDKTRIEEVMALMELDGLSK----KKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:COG4172   382 -GQIIaeglrvhGPGLSAAERRARVAEALEEVGLDPaarhRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSV 460

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1238650805 167 RSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG4172   461 QAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVF 514
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 21-211 7.27e-30

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 112.24  E-value: 7.27e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRV--YFDSHKGFNlpiqqrkigfvfqnyalfPHLNVY 98
Cdd:cd03220    41 VSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRVssLLGLGGGFN------------------PELTGR 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENIIF-----GHSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQ 171
Cdd:cd03220   103 ENIYLngrllGLSRKeiDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQ 182

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1238650805 172 EELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIA 211
Cdd:cd03220   183 RRLRELLKQ-GKTVILVSHDPSSIKRLCDRALVLEKGKIR 221
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 21-210 9.75e-30

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 111.91  E-value: 9.75e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRivvgnrVYFDshkgfNLPIQQ-------RKIGFVFQNYALFp 93
Cdd:cd03245    23 VSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGS------VLLD-----GTDIRQldpadlrRNIGYVPQDVTLF- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENIIFGH-SGDKTRIEEVMALMELDGLSKK-----------KITALSGGQAQRVALARALASSPDILLLDEPLSA 161
Cdd:cd03245    91 YGTLRDNITLGApLADDERILRAAELAGVTDFVNKhpngldlqigeRGRGLSGGQRQAVALARALLNDPPILLLDEPTSA 170

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1238650805 162 LDGEMRSKLQEELKRLIAHfgITAFLVSHDLgEVFKLSDEVICLQDGKI 210
Cdd:cd03245   171 MDMNSEERLKERLRQLLGD--KTLIIITHRP-SLLDLVDRIIVMDSGRI 216
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 14-210 1.09e-29

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 112.98  E-value: 1.09e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  14 HGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVY---FDSHKGFnlpiqQRKIGFVFQNY 89
Cdd:TIGR02769  23 RAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFrGQDLYqldRKQRRAF-----RRDVQLVFQDS 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  90 --ALFPHLNVYENI--------IFGHSGDKTRIEEVMALMELDGLSKKKITA-LSGGQAQRVALARALASSPDILLLDEP 158
Cdd:TIGR02769  98 psAVNPRMTVRQIIgeplrhltSLDESEQKARIAELLDMVGLRSEDADKLPRqLSGGQLQRINIARALAVKPKLIVLDEA 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 159 LSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:TIGR02769 178 VSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQI 229
cbiO PRK13643
energy-coupling factor transporter ATPase;
18-251 1.18e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 113.68  E-value: 1.18e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRKIGFVFQnyalFPHLNV 97
Cdd:PRK13643   22 LFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKEIKPVRKKVGVVFQ----FPESQL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YE-----NIIFGHSG---DKTRIEEVMA-LMELDGLSK----KKITALSGGQAQRVALARALASSPDILLLDEPLSALDG 164
Cdd:PRK13643   98 FEetvlkDVAFGPQNfgiPKEKAEKIAAeKLEMVGLADefweKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDP 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 165 EMRSKLQeELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL--------------SDRFSAKLQ 230
Cdd:PRK13643  178 KARIEMM-QLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQevdflkahelgvpkATHFADQLQ 256

                         250       260
                  ....*....|....*....|....*
gi 1238650805 231 ING----EILKITPQSLITIVDVLS 251
Cdd:PRK13643  257 KTGavtfEKLPITRAELVTLLTSLS 281
cbiO PRK13649
energy-coupling factor transporter ATPase;
15-239 1.21e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 113.30  E-value: 1.21e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  15 GTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRKIGFVFQnyalFPH 94
Cdd:PRK13649   20 GRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIKQIRKKVGLVFQ----FPE 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYE-----NIIFGHSGDKTRIEEVMAL----MELDGLSK----KKITALSGGQAQRVALARALASSPDILLLDEPLSA 161
Cdd:PRK13649   96 SQLFEetvlkDVAFGPQNFGVSQEEAEALarekLALVGISEslfeKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAG 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 162 LDGEMRSKLQEELKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSAKLQINgeILKIT 239
Cdd:PRK13649  176 LDPKGRKELMTLFKKL-HQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQDVDFLEEKQLG--VPKIT 250
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 21-220 3.28e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 112.09  E-value: 3.28e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDSHKGFNLpiqQRKIGFVFQNY--ALFPHlNV 97
Cdd:PRK13639   21 INFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIkGEPIKYDKKSLLEV---RKTVGIVFQNPddQLFAP-TV 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:PRK13639   97 EEDVAFGplnlglsKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQI 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1238650805 171 QEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK13639  177 MKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVF 225
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 21-206 3.53e-29

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 110.57  E-value: 3.53e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVvgnrvyFDSHKGFNLPIQQ--RKIGFVFQNYALFPHlNVY 98
Cdd:PRK10247   26 ISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLL------FEGEDISTLKPEIyrQQVSYCAQTPTLFGD-TVY 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENIIF-----GHSGDKTRIEEVMALMEL-DGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:PRK10247   99 DNLIFpwqirNQQPDPAIFLDDLERFALpDTILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNE 178

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1238650805 173 ELKRLIAHFGITAFLVSHDLGEVfKLSDEVICLQ 206
Cdd:PRK10247  179 IIHRYVREQNIAVLWVTHDKDEI-NHADKVITLQ 211
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
14-210 3.68e-29

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 111.70  E-value: 3.68e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  14 HGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNR----VYFDSHKGFnlpiqQRKIGFVFQNY 89
Cdd:PRK10419   24 HQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEplakLNRAQRKAF-----RRDIQMVFQDS 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  90 --ALFPHLNVYEnII---------FGHSGDKTRIEEVMALMELD-GLSKKKITALSGGQAQRVALARALASSPDILLLDE 157
Cdd:PRK10419   99 isAVNPRKTVRE-IIreplrhllsLDKAERLARASEMLRAVDLDdSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDE 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 158 PLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:PRK10419  178 AVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQI 230
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 16-227 5.87e-29

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 113.78  E-value: 5.87e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  16 TFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNR-VYFDSHKGFNLPI----QQRKIGFVFQNYA 90
Cdd:PRK09536   17 TVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDdVEALSARAASRRVasvpQDTSLSFEFDVRQ 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LF-----PHLNVYENIifgHSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGE 165
Cdd:PRK09536   97 VVemgrtPHRSRFDTW---TETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLDIN 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 166 MRSKLQEELKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSA 227
Cdd:PRK09536  174 HQVRTLELVRRL-VDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTADTLRA 234
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
20-247 5.92e-29

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 112.62  E-value: 5.92e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfdshKGFNLPIQQR----KIGFVFQNYALFPHL 95
Cdd:PRK13536   59 GLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITV---------LGVPVPARARlaraRIGVVPQFDNLDLEF 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  96 NVYEN-IIFG-HSGDKTR-IEEVM-ALMELDGLSKK---KITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRS 168
Cdd:PRK13536  130 TVRENlLVFGrYFGMSTReIEAVIpSLLEFARLESKadaRVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARH 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 169 KLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFlsdrfsaKLQINGEILKI---TPQSLIT 245
Cdd:PRK13536  210 LIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHALI-------DEHIGCQVIEIyggDPHELSS 281


                  ..
gi 1238650805 246 IV 247
Cdd:PRK13536  282 LV 283
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 18-219 7.60e-29

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 109.92  E-value: 7.60e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVvgnrvyFDSHKGFNLPIQQRK---IGFVFQNYALFPH 94
Cdd:TIGR03410  16 LRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIR------LDGEDITKLPPHERAragIAYVPQGREIFPR 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENIIFGHSG----DKTRIEEVMALME-LDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSK 169
Cdd:TIGR03410  90 LTVEENLLTGLAAlprrSRKIPDEIYELFPvLKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEPTEGIQPSIIKD 169

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1238650805 170 LQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:TIGR03410 170 IGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDEL 219
cbiO PRK13644
energy-coupling factor transporter ATPase;
18-256 7.98e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 110.85  E-value: 7.98e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNrvyFDSHKGFNLPIQQRKIGFVFQN-YALFPHLN 96
Cdd:PRK13644   18 LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSG---IDTGDFSKLQGIRKLVGIVFQNpETQFVGRT 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 VYENIIFGHSG-------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSK 169
Cdd:PRK13644   95 VEEDLAFGPENlclppieIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIA 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 170 LQEELKRLiAHFGITAFLVSHDLGEVfKLSDEVICLQDGKIAKRGTPDEVFlSDrfsaklqINGEILKITPQSLITIVDV 249
Cdd:PRK13644  175 VLERIKKL-HEKGKTIVYITHNLEEL-HDADRIIVMDRGKIVLEGEPENVL-SD-------VSLQTLGLTPPSLIELAEN 244


                  ....*..
gi 1238650805 250 LSNGSIV 256
Cdd:PRK13644  245 LKMHGVV 251
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 11-220 8.77e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 111.09  E-value: 8.77e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  11 DGNHGtfLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGF-NLpiqQRKIGFVFQ-- 87
Cdd:PRK13636   17 DGTHA--LKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDYSRKGLmKL---RESVGMVFQdp 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  88 NYALFPhLNVYENIIFGHSGDK-------TRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:PRK13636   92 DNQLFS-ASVYQDVSFGAVNLKlpedevrKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTA 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 161 ALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK13636  171 GLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF 230
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
21-240 9.12e-29

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 110.49  E-value: 9.12e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYfdshKGFNLPIQQRKIGFVFQNYALFPHLNVYEN 100
Cdd:PRK11231   21 LSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPI----SMLSSRQLARRLALLPQHHLTPEGITVREL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFGHS-----------GDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDgemrSK 169
Cdd:PRK11231   97 VAYGRSpwlslwgrlsaEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLD----IN 172

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 170 LQEELKRLIAHF---GITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF----LSDRFSAKLQINGEILKITP 240
Cdd:PRK11231  173 HQVELMRLMRELntqGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVMtpglLRTVFDVEAEIHPEPVSGTP 250
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 21-224 1.34e-28

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 109.62  E-value: 1.34e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGL-ENPDKGRivVGNRVYFDSHKGFNLPIQQ--RKIGFVFQNYALFPHLNV 97
Cdd:PRK14247   22 VNLEIPDNTITALMGPSGSGKSTLLRVFNRLiELYPEAR--VSGEVYLDGQDIFKMDVIElrRRVQMVFQIPNPIPNLSI 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFGHSGDK---------TRIEEVMALMELDGLSKKKITA----LSGGQAQRVALARALASSPDILLLDEPLSALDG 164
Cdd:PRK14247  100 FENVALGLKLNRlvkskkelqERVRWALEKAQLWDEVKDRLDApagkLSGGQQQRLCIARALAFQPEVLLADEPTANLDP 179

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 165 EMRSKLQE---ELKRliahfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDR 224
Cdd:PRK14247  180 ENTAKIESlflELKK-----DMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPR 237
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 21-220 2.57e-28

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 114.19  E-value: 2.57e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNrvyfdshkgfnLPIQQ-------RKIGFVFQNYALFp 93
Cdd:TIGR03375 484 VSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDG-----------VDIRQidpadlrRNIGYVPQDPRLF- 551

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENIIFG--HSGDktriEEVMALMELDGLSK----------KKIT----ALSGGQAQRVALARALASSPDILLLDE 157
Cdd:TIGR03375 552 YGTLRDNIALGapYADD----EEILRAAELAGVTEfvrrhpdgldMQIGergrSLSGGQRQAVALARALLRDPPILLLDE 627

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 158 PLSALDGEMRSKLQEELKRLIAhfGITAFLVSHDLgEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:TIGR03375 628 PTSAMDNRSEERFKDRLKRWLA--GKTLVLVTHRT-SLLDLVDRIIVMDNGRIVADGPKDQVL 687
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
21-210 3.33e-28

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 108.04  E-value: 3.33e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSH-----KGFNLPIQQRKIGFVFQNYALFPHL 95
Cdd:PRK10908   21 VTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKI------WFSGHditrlKNREVPFLRRQIGMIFQDHHLLMDR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  96 NVYEN-----IIFGHSGDKTRIEEVMALMELDGLSKKK--ITALSGGQAQRVALARALASSPDILLLDEPLSALDGEmrs 168
Cdd:PRK10908   95 TVYDNvaiplIIAGASGDDIRRRVSAALDKVGLLDKAKnfPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDA--- 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1238650805 169 kLQEELKRLIAHF---GITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:PRK10908  172 -LSEGILRLFEEFnrvGVTVLMATHDIGLISRRSYRMLTLSDGHL 215
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 21-265 3.58e-28

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 109.81  E-value: 3.58e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKgfnlpiqqRKIGFVFQNYALFPHLNVYEN 100
Cdd:COG4152    20 VSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPEDR--------RRIGYLPEERGLYPKMKVGEQ 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIF-----GHSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE 173
Cdd:COG4152    92 LVYlarlkGLSKAeaKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSGLDPVNVELLKDV 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 174 LKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVflSDRFSA-KLQINGEILKITPQSLITIVDVLSN 252
Cdd:COG4152   172 IRELAAK-GTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEI--RRQFGRnTLRLEADGDAGWLRALPGVTVVEED 248

                         250
                  ....*....|...
gi 1238650805 253 GSIVRIVLAPSEA 265
Cdd:COG4152   249 GDGAELKLEDGAD 261
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
21-223 7.70e-28

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 109.12  E-value: 7.70e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRI-VVGNRVYFDSHKGfnlpiqQRKIGFVFQNYALFPHLNVYE 99
Cdd:PRK13537   26 LSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSIsLCGEPVPSRARHA------RQRVGVVPQFDNLDPDFTVRE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NII-----FGHSGDKTRiEEVMALMELDGLSKK---KITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQ 171
Cdd:PRK13537  100 NLLvfgryFGLSAAAAR-ALVPPLLEFAKLENKadaKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQARHLMW 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 172 EELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSD 223
Cdd:PRK13537  179 ERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIESE 229
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 21-191 7.94e-28

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 112.08  E-value: 7.94e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVyfdshkgfnlpiqqrKIGFVFQNYALFPHLNVYEN 100
Cdd:COG0488    17 VSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGL---------------RIGYLPQEPPLDDDLTVLDT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFGHSG------DKTRIEEVMALMELDG-------------------------LSK---------KKITALSGGQAQRV 140
Cdd:COG0488    82 VLDGDAElraleaELEELEAKLAEPDEDLerlaelqeefealggweaearaeeiLSGlgfpeedldRPVSELSGGWRRRV 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 141 ALARALASSPDILLLDEPLSALDGEMRSKLQEELKRliahFGITAFLVSHD 191
Cdd:COG0488   162 ALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKN----YPGTVLVVSHD 208
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 8-220 8.46e-28

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 109.28  E-value: 8.46e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   8 KTLDGnhgtfllqVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDSHKGFNLpiQQRKIGFVF 86
Cdd:PRK11308   29 KALDG--------VSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYqGQDLLKADPEAQKL--LRQKIQIVF 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  87 QN-YAlfpHLNVYENI---------IFGHSGDKTRIEEVMALMELDGL----SKKKITALSGGQAQRVALARALASSPDI 152
Cdd:PRK11308   99 QNpYG---SLNPRKKVgqileepllINTSLSAAERREKALAMMAKVGLrpehYDRYPHMFSGGQRQRIAIARALMLDPDV 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 153 LLLDEPLSALDGEMRSK-------LQEELKrliahfgiTAFL-VSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK11308  176 VVADEPVSALDVSVQAQvlnlmmdLQQELG--------LSYVfISHDLSVVEHIADEVMVMYLGRCVEKGTKEQIF 243
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 13-224 8.73e-28

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 107.83  E-value: 8.73e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  13 NHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNL-PIQQRK-IGFVFQNYA 90
Cdd:PRK14246   21 NDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYFGKDIFQIdAIKLRKeVGMVFQQPN 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPHLNVYENIIF---GHS-GDKTRIEEVMA-LMELDGLSKK-------KITALSGGQAQRVALARALASSPDILLLDEP 158
Cdd:PRK14246  101 PFPHLSIYDNIAYplkSHGiKEKREIKKIVEeCLRKVGLWKEvydrlnsPASQLSGGQQQRLTIARALALKPKVLLMDEP 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805 159 LSALD---GEMRSKLQEELKRliahfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDR 224
Cdd:PRK14246  181 TSMIDivnSQAIEKLITELKN-----EIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPK 244
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 21-229 1.01e-27

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 112.12  E-value: 1.01e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVvgnrvyFDSHkgfnlPIQ-------QRKIGFVFQNYALFP 93
Cdd:TIGR02203 351 ISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQIL------LDGH-----DLAdytlaslRRQVALVSQDVVLFN 419

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HlNVYENIIFGHSG--DKTRIEEVMA---LMEL-DGLSK-------KKITALSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:TIGR02203 420 D-TIANNIAYGRTEqaDRAEIERALAaayAQDFvDKLPLgldtpigENGVLLSGGQRQRLAIARALLKDAPILILDEATS 498

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805 161 ALDGEMRSKLQEELKRLIAhfGITAFLVSHDLGEVFKlSDEVICLQDGKIAKRGTPDEVFLSDRFSAKL 229
Cdd:TIGR02203 499 ALDNESERLVQAALERLMQ--GRTTLVIAHRLSTIEK-ADRIVVMDDGRIVERGTHNELLARNGLYAQL 564
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 20-205 1.12e-27

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 111.61  E-value: 1.12e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdSHKGFNLPIQQRKIGFVFQNYALFPHlNVYE 99
Cdd:TIGR02857 340 PVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGV----PLADADADSWRDQIAWVPQHPFLFAG-TIAE 414

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NIIFGHSG-DKTRIEEVMALMELDGLSK-------KKI----TALSGGQAQRVALARALASSPDILLLDEPLSALDGEMR 167
Cdd:TIGR02857 415 NIRLARPDaSDAEIREALERAGLDEFVAalpqgldTPIgeggAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETE 494

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1238650805 168 SKLQEELKRLIAhfGITAFLVSHDLgEVFKLSDEVICL 205
Cdd:TIGR02857 495 AEVLEALRALAQ--GRTVLLVTHRL-ALAALADRIVVL 529
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 21-210 1.14e-27

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 106.21  E-value: 1.14e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKgfnlpiqqRKIGFVFQNYALFPHLNVYEN 100
Cdd:cd03269    19 ISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAAR--------NRIGYLPEERGLYPKMKVIDQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIF-------GHSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE 173
Cdd:cd03269    91 LVYlaqlkglKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLKDV 170

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1238650805 174 LKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:cd03269   171 IREL-ARAGKTVILSTHQMELVEELCDRVLLLNKGRA 206
cbiO PRK13645
energy-coupling factor transporter ATPase;
18-232 1.72e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 107.79  E-value: 1.72e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGN-RVYFDSHKGFNLPIQQRKIGFVFQ--NYALFPH 94
Cdd:PRK13645   27 LNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDyAIPANLKKIKEVKRLRKEIGLVFQfpEYQLFQE 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 lNVYENIIFG--HSGDKT-----RIEEVMALMEL-DGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:PRK13645  107 -TIEKDIAFGpvNLGENKqeaykKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKG 185

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 167 RSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSAKLQIN 232
Cdd:PRK13645  186 EEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFSNQELLTKIEID 251
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 21-226 2.50e-27

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 105.88  E-value: 2.50e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQQRK---IGFVFQNYALFPHLNV 97
Cdd:COG1137    22 VSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRI------FLDGEDITHLPMHKRArlgIGYLPQEASIFRKLTV 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENII----FGHSGDKTRIEEVMALME---LDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDgemrSKL 170
Cdd:COG1137    96 EDNILavleLRKLSKKEREERLEELLEefgITHLRKSKAYSLSGGERRRVEIARALATNPKFILLDEPFAGVD----PIA 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 171 QEELKRLIAHF---GITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDE---------VFLSDRFS 226
Cdd:COG1137   172 VADIQKIIRHLkerGIGVLITDHNVRETLGICDRAYIISEGKVLAEGTPEEilnnplvrkVYLGEDFR 239
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
6-220 2.78e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 107.10  E-value: 2.78e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   6 FEKTLDGNHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNrvyFDSHKGFNLPIQQRKIGFV 85
Cdd:PRK13633   14 YESNEESTEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDG---LDTSDEENLWDIRNKAGMV 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  86 FQNyalfPHLN-----VYENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDIL 153
Cdd:PRK13633   91 FQN----PDNQivatiVEEDVAFGpenlgipPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECI 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 154 LLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKlSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK13633  167 IFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIF 232
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 21-210 4.54e-27

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 109.77  E-value: 4.54e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRV---YFDshkgfnlpiQQRKigfvfqnyALFPHLNV 97
Cdd:COG0488   334 LSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLGETVkigYFD---------QHQE--------ELDPDKTV 396

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIifGHSGDKTRIEEVMALMELDGLS----KKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRsklqEE 173
Cdd:COG0488   397 LDEL--RDGAPGGTEQEVRGYLGRFLFSgddaFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLDIETL----EA 470

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1238650805 174 LKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:COG0488   471 LEEALDDFPGTVLLVSHDRYFLDRVATRILEFEDGGV 507
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 21-220 5.57e-27

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 105.50  E-value: 5.57e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGL--ENPD---KGRIVVGNR-VYfdsHKGFNLPIQQRKIGFVFQNYALFPH 94
Cdd:COG1117    30 INLDIPENKVTALIGPSGCGKSTLLRCLNRMndLIPGarvEGEILLDGEdIY---DPDVDVVELRRRVGMVFQKPNPFPK 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 lNVYENIIFG---HsGDKTRiEEVMALME--L----------DGLsKKKITALSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:COG1117   107 -SIYDNVAYGlrlH-GIKSK-SELDEIVEesLrkaalwdevkDRL-KKSALGLSGGQQQRLCIARALAVEPEVLLMDEPT 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 160 SALDGEMRSKLQEELKRLIAHFGITafLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG1117   183 SALDPISTAKIEELILELKKDYTIV--IVTHNMQQAARVSDYTAFFYLGELVEFGPTEQIF 241
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
13-225 1.38e-26

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 104.71  E-value: 1.38e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  13 NHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDK---GRI-VVGNRVYFDSHKGFNLPIQQRKIGFVFQN 88
Cdd:PRK09984   15 NQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKsagSHIeLLGRTVQREGRLARDIRKSRANTGYIFQQ 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  89 YALFPHLNVYENIIFGHSGDK----------TRIEEVMALMELDGL-----SKKKITALSGGQAQRVALARALASSPDIL 153
Cdd:PRK09984   95 FNLVNRLSVLENVLIGALGSTpfwrtcfswfTREQKQRALQALTRVgmvhfAHQRVSTLSGGQQQRVAIARALMQQAKVI 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 154 LLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEvFLSDRF 225
Cdd:PRK09984  175 LADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQ-FDNERF 245
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 11-209 1.45e-26

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 102.93  E-value: 1.45e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  11 DGNHGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkgfnlpiqqrkIGFVFQNy 89
Cdd:cd03250    13 GEQETSFTLKdINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS-----------------IAYVSQE- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  90 alfP-HLN--VYENIIFGHSGDKTRIEEVM---ALME-LDGLSK--------KKITaLSGGQAQRVALARALASSPDILL 154
Cdd:cd03250    75 ---PwIQNgtIRENILFGKPFDEERYEKVIkacALEPdLEILPDgdlteigeKGIN-LSGGQKQRISLARAVYSDADIYL 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1238650805 155 LDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLgEVFKLSDEVICLQDGK 209
Cdd:cd03250   151 LDDPLSAVDAHVGRHIFENCILGLLLNNKTRILVTHQL-QLLPHADQIVVLDNGR 204
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 21-220 1.69e-26

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 104.15  E-value: 1.69e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGL--ENPD---KGRI-VVGNRVYFDSHKgfnlPIQ-QRKIGFVFQNYALFP 93
Cdd:PRK14267   23 VDLKIPQNGVFALMGPSGCGKSTLLRTFNRLleLNEEarvEGEVrLFGRNIYSPDVD----PIEvRREVGMVFQYPNPFP 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENIIFGHS-----GDKTRIEEVM--ALM------ELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:PRK14267   99 HLTIYDNVAIGVKlnglvKSKKELDERVewALKkaalwdEVKDRLNDYPSNLSGGQRQRLVIARALAMKPKILLMDEPTA 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 161 ALDGEMRSKLQEELKRLIAHFGITafLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK14267  179 NIDPVGTAKIEELLFELKKEYTIV--LVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVF 236
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 21-220 2.09e-26

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 107.85  E-value: 2.09e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKT----TILRILsglenPDKGRIVVGnRVYFDSHKGFNLPIQQ------RKIGFVFQN-- 88
Cdd:COG4172    29 VSFDIAAGETLALVGESGSGKSvtalSILRLL-----PDPAAHPSG-SILFDGQDLLGLSERElrrirgNRIAMIFQEpm 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  89 YALFPHLNVYENII------FGHSGDKTRiEEVMALMELDGL--SKKKITA----LSGGQAQRVALARALASSPDILLLD 156
Cdd:COG4172   103 TSLNPLHTIGKQIAevlrlhRGLSGAAAR-ARALELLERVGIpdPERRLDAyphqLSGGQRQRVMIAMALANEPDLLIAD 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1238650805 157 EPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG4172   182 EPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAELF 245
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 21-210 2.53e-26

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 101.52  E-value: 2.53e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfDSHKgFNLPIQQRKIGFVFQNYALFPHlNVYEN 100
Cdd:cd03246    21 VSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGA---DISQ-WDPNELGDHVGYLPQDDELFSG-SIAEN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IifghsgdktrieevmalmeldglskkkitaLSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAH 180
Cdd:cd03246    96 I------------------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQAIAALKAA 145

                         170       180       190
                  ....*....|....*....|....*....|
gi 1238650805 181 fGITAFLVSHDLgEVFKLSDEVICLQDGKI 210
Cdd:cd03246   146 -GATRIVIAHRP-ETLASADRILVLEDGRV 173
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 16-224 2.63e-26

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 104.41  E-value: 2.63e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  16 TFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENP-----DKGRIVVGNRVYFDSHKGFNLpiqQRKIGFVFQNYA 90
Cdd:PRK14271   35 TVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKvsgyrYSGDVLLGGRSIFNYRDVLEF---RRRVGMLFQRPN 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPhLNVYENIIFGhsgdkTRIEEVMALMELDGLSKKKITA-----------------LSGGQAQRVALARALASSPDIL 153
Cdd:PRK14271  112 PFP-MSIMDNVLAG-----VRAHKLVPRKEFRGVAQARLTEvglwdavkdrlsdspfrLSGGQQQLLCLARTLAVNPEVL 185

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 154 LLDEPLSALDGEMRSKLQEELKRLIAHfgITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDR 224
Cdd:PRK14271  186 LLDEPTSALDPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPK 254
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 21-219 4.40e-26

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 107.20  E-value: 4.40e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnRVYFD----SHKGFNLPIQ-QRKIGFVFQNYALFPHL 95
Cdd:TIGR03269 303 VSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNV--RVGDEwvdmTKPGPDGRGRaKRYIGILHQEYDLYPHR 380

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  96 NVYENI---IFGHSGDKTRIEEVMALMELDGLSKKKITA--------LSGGQAQRVALARALASSPDILLLDEPLSALDG 164
Cdd:TIGR03269 381 TVLDNLteaIGLELPDELARMKAVITLKMVGFDEEKAEEildkypdeLSEGERHRVALAQVLIKEPRIVILDEPTGTMDP 460

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1238650805 165 EMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:TIGR03269 461 ITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEI 515
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 18-219 4.53e-26

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 107.20  E-value: 4.53e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLEN--PDKGRIV--VG-----NRVYFDSHKGFNLPI----------- 77
Cdd:TIGR03269  16 LKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQyePTSGRIIyhVAlcekcGYVERPSKVGEPCPVcggtlepeevd 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  78 -----------QQRKIGFVFQ-NYALFPHLNVYENII-----FGHSGDKTrIEEVMALMELDGLSKKkIT----ALSGGQ 136
Cdd:TIGR03269  96 fwnlsdklrrrIRKRIAIMLQrTFALYGDDTVLDNVLealeeIGYEGKEA-VGRAVDLIEMVQLSHR-IThiarDLSGGE 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 137 AQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTP 216
Cdd:TIGR03269 174 KQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKAIWLENGEIKEEGTP 253


                  ...
gi 1238650805 217 DEV 219
Cdd:TIGR03269 254 DEV 256
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
11-210 5.10e-26

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 102.59  E-value: 5.10e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  11 DGNHGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRKIGFVFQNY 89
Cdd:PRK11629   17 EGSVQTDVLHnVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQFH 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  90 ALFPHLNVYENI----IFGHSGDK---TRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSAL 162
Cdd:PRK11629   97 HLLPDFTALENVamplLIGKKKPAeinSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNL 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1238650805 163 DGEMRSKLQEELKRLIAHFGiTAFL-VSHDLGEVFKLSDEVIcLQDGKI 210
Cdd:PRK11629  177 DARNADSIFQLLGELNRLQG-TAFLvVTHDLQLAKRMSRQLE-MRDGRL 223
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 12-210 5.64e-26

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 102.16  E-value: 5.64e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  12 GNHGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRI-VVGNRVYFDSHKGfNLPIQQRKIGFVFQNY 89
Cdd:PRK10584   19 GEHELSILTgVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVsLVGQPLHQMDEEA-RAKLRAKHVGFVFQSF 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  90 ALFPHLNVYENI-----IFGHSGDKTRiEEVMALMELDGLSK--KKITA-LSGGQAQRVALARALASSPDILLLDEPLSA 161
Cdd:PRK10584   98 MLIPTLNALENVelpalLRGESSRQSR-NGAKALLEQLGLGKrlDHLPAqLSGGEQQRVALARAFNGRPDVLFADEPTGN 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1238650805 162 LDGEMRSKLQEELKRLIAHFGITAFLVSHDLgEVFKLSDEVICLQDGKI 210
Cdd:PRK10584  177 LDRQTGDKIADLLFSLNREHGTTLILVTHDL-QLAARCDRRLRLVNGQL 224
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
18-195 6.82e-26

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 100.77  E-value: 6.82e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkgfnlpiqqRKIGFVFQNYAL---FPh 94
Cdd:NF040873    8 LHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGG---------------ARVAYVPQRSEVpdsLP- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENI---IFGHSG--------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALD 163
Cdd:NF040873   72 LTVRDLVamgRWARRGlwrrltrdDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLD 151

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1238650805 164 GEMRSKLQEELKRLIAHfGITAFLVSHDLGEV 195
Cdd:NF040873  152 AESRERIIALLAEEHAR-GATVVVVTHDLELV 182
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 21-272 7.12e-26

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 104.01  E-value: 7.12e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFnlpiqQRKIGFVF-QNYALFPHLNVYE 99
Cdd:COG4586    41 ISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGYVPFKRRKEF-----ARRIGVVFgQRSQLWWDLPAID 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NI-----IFGHSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:COG4586   116 SFrllkaIYRIPDAeyKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIRE 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 173 ELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEvfLSDRFSAK---------------LQINGEILK 237
Cdd:COG4586   196 FLKEYNRERGTTILLTSHDMDDIEALCDRVIVIDHGRIIYDGSLEE--LKERFGPYktivlelaepvppleLPRGGEVIE 273

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1238650805 238 ITPQSL-ITIVDVLSNGSIVRIVLAPSEAKHFRVGD 272
Cdd:COG4586   274 REGNRVrLEVDPRESLAEVLARLLARYPVRDLTIEE 309
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 21-231 8.31e-26

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 103.78  E-value: 8.31e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVG---NRVYFDSHKGFNLPIQQ---------RKIGFVFQ- 87
Cdd:PRK13631   45 ISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGdiyIGDKKNNHELITNPYSKkiknfkelrRRVSMVFQf 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  88 -NYALFPHlNVYENIIFGHSGDKTRIEEVMAL----MELDGLSKKKIT----ALSGGQAQRVALARALASSPDILLLDEP 158
Cdd:PRK13631  125 pEYQLFKD-TIEKDIMFGPVALGVKKSEAKKLakfyLNKMGLDDSYLErspfGLSGGQKRRVAIAGILAIQPEILIFDEP 203

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 159 LSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSAKLQI 231
Cdd:PRK13631  204 TAGLDPKGEHEMMQLILDAKAN-NKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIFTDQHIINSTSI 275
cbiO PRK13640
energy-coupling factor transporter ATPase;
20-220 8.54e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 102.96  E-value: 8.54e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPD---KGRIVVgnrvyfdshKGFNLPIQ-----QRKIGFVFQNY-A 90
Cdd:PRK13640   25 DISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDdnpNSKITV---------DGITLTAKtvwdiREKVGIVFQNPdN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPHLNVYENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALD 163
Cdd:PRK13640   96 QFVGATVGDDVAFGlenravpRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLD 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 164 GEMRSKLQEELKRLIAHFGITAFLVSHDLGEVfKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK13640  176 PAGKEQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEIF 231
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 21-219 1.19e-25

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 101.99  E-value: 1.19e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVvgnrvyFDSHKGFNLPIQQ--RKiGFV--FQNYALFPHLN 96
Cdd:PRK11300   24 VNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTIL------LRGQHIEGLPGHQiaRM-GVVrtFQHVRLFREMT 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 VYENIIFG-HSGDKT------------RIEEVMAL---------MELDGLSKKKITALSGGQAQRVALARALASSPDILL 154
Cdd:PRK11300   97 VIENLLVAqHQQLKTglfsgllktpafRRAESEALdraatwlerVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILM 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805 155 LDEPLSALDgemrSKLQEELKRLIA----HFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:PRK11300  177 LDEPAAGLN----PKETKELDELIAelrnEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEI 241
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 1-214 1.21e-25

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 100.32  E-value: 1.21e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELDFE------KTLDGNHGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENP--DKGRIVVGnrvyfdshk 71
Cdd:cd03213     1 GVTLSFRnltvtvKSSPSKSGKQLLKnVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGlgVSGEVLIN--------- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  72 GFNLPIQ--QRKIGFVFQNYALFPHLNVYENIIFGhsgdktrieevmalmeldglskKKITALSGGQAQRVALARALASS 149
Cdd:cd03213    72 GRPLDKRsfRKIIGYVPQDDILHPTLTVRETLMFA----------------------AKLRGLSGGERKRVSIALELVSN 129

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 150 PDILLLDEPLSALDGEMRSKLQEELKRLiAHFGITAFLVSHDL-GEVFKLSDEVICLQDGKIAKRG 214
Cdd:cd03213   130 PSLLFLDEPTSGLDSSSALQVMSLLRRL-ADTGRTIICSIHQPsSEIFELFDKLLLLSQGRVIYFG 194
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 21-252 4.01e-25

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 101.70  E-value: 4.01e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgNRVYFDSHKGFN----------LPIQ------------ 78
Cdd:PRK13651   26 VSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTI---EWIFKDEKNKKKtkekekvlekLVIQktrfkkikkike 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  79 -QRKIGFVFQ--NYALFPHlNVYENIIFGHSGDKTRIEEVMAL----MELDGLS----KKKITALSGGQAQRVALARALA 147
Cdd:PRK13651  103 iRRRVGVVFQfaEYQLFEQ-TIEKDIIFGPVSMGVSKEEAKKRaakyIELVGLDesylQRSPFELSGGQKRRVALAGILA 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 148 SSPDILLLDEPLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFsa 227
Cdd:PRK13651  182 MEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDLDNVLEWTKRTIFFKDGKIIKDGDTYDILSDNKF-- 258

                         250       260
                  ....*....|....*....|....*
gi 1238650805 228 kLQINgeilKITPQSLITIVDVLSN 252
Cdd:PRK13651  259 -LIEN----NMEPPKLLNFVNKLEK 278
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 14-200 4.53e-25

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 100.63  E-value: 4.53e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  14 HGTFLL--QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDShkgfNL------PIQ-QRKIGF 84
Cdd:PRK14243   20 YGSFLAvkNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLIPGFRVEGKVTFHGK----NLyapdvdPVEvRRRIGM 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  85 VFQNYALFPHlNVYENIIFG-----HSGDKTRI-----------EEVMALMELDGLSkkkitaLSGGQAQRVALARALAS 148
Cdd:PRK14243   96 VFQKPNPFPK-SIYDNIAYGaringYKGDMDELverslrqaalwDEVKDKLKQSGLS------LSGGQQQRLCIARAIAV 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 149 SPDILLLDEPLSALDGEMRSKLQEELKRLIAHFgiTAFLVSHDLGEVFKLSD 200
Cdd:PRK14243  169 QPEVILMDEPCSALDPISTLRIEELMHELKEQY--TIIIVTHNMQQAARVSD 218
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 21-210 5.59e-25

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 100.55  E-value: 5.59e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNR-VYfdshkgfNLPIQQR--KIGFVFQNYAL--FPHL 95
Cdd:COG1101    25 LNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKdVT-------KLPEYKRakYIGRVFQDPMMgtAPSM 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  96 NVYENII----------FGHSGDKTRIEEVMALME-LD-GLSKK---KITALSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:COG1101    98 TIEENLAlayrrgkrrgLRRGLTKKRRELFRELLAtLGlGLENRldtKVGLLSGGQRQALSLLMATLTKPKLLLLDEHTA 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1238650805 161 ALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:COG1101   178 ALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGRI 227
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 20-195 6.27e-25

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 98.72  E-value: 6.27e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYfdshkGFNLPIQQRKIGFVFQNYALFPHLNVYE 99
Cdd:cd03231    18 GLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPL-----DFQRDSIARGLLYLGHAPGIKTTLSVLE 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NIIFGHS-GDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKRLI 178
Cdd:cd03231    93 NLRFWHAdHSDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAGHC 172

                         170
                  ....*....|....*..
gi 1238650805 179 AHFGITAFLVSHDLGEV 195
Cdd:cd03231   173 ARGGMVVLTTHQDLGLS 189
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 18-221 7.39e-25

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 99.85  E-value: 7.39e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYfdshKGFNL------PIQQRK-IGFVFQNYA 90
Cdd:PRK14239   21 LNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDLNPEVTITGSIVY----NGHNIysprtdTVDLRKeIGMVFQQPN 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPhLNVYENIIFGHS----GDKTRIEEVMAlMELDGLS-----KKKI----TALSGGQAQRVALARALASSPDILLLDE 157
Cdd:PRK14239   97 PFP-MSIYENVVYGLRlkgiKDKQVLDEAVE-KSLKGASiwdevKDRLhdsaLGLSGGQQQRVCIARVLATSPKIILLDE 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1238650805 158 PLSALDGEMRSKLQEELKRLIAHFgiTAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFL 221
Cdd:PRK14239  175 PTSALDPISAGKIEETLLGLKDDY--TMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFM 236
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 21-218 1.12e-24

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 103.36  E-value: 1.12e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGnrvyfdshkGFNLP-IQQ----RKIGFVFQNYALFphl 95
Cdd:COG5265   377 VSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILID---------GQDIRdVTQaslrAAIGIVPQDTVLF--- 444

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  96 N--VYENIIFGHSG-DKTRIEEVMALMELD----GLSKKKITA-------LSGGQAQRVALARALASSPDILLLDEPLSA 161
Cdd:COG5265   445 NdtIAYNIAYGRPDaSEEEVEAAARAAQIHdfieSLPDGYDTRvgerglkLSGGEKQRVAIARTLLKNPPILIFDEATSA 524

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 162 LDGEMRSKLQEELKRL--------IAHfgitaflvshdlgevfKLS-----DEVICLQDGKIAKRGTPDE 218
Cdd:COG5265   525 LDSRTERAIQAALREVargrttlvIAH----------------RLStivdaDEILVLEAGRIVERGTHAE 578
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
21-223 1.34e-24

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 99.68  E-value: 1.34e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRivvgnrVYFDSHKgfnlpIQQ-------RKIGFVFQNYALFP 93
Cdd:PRK10253   26 LTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGH------VWLDGEH-----IQHyaskevaRRIGLLAQNATTPG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENIIFG---HSGDKTRI-----EEVMALMELDG---LSKKKITALSGGQAQRVALARALASSPDILLLDEPLSAL 162
Cdd:PRK10253   95 DITVQELVARGrypHQPLFTRWrkedeEAVTKAMQATGithLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWL 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 163 DGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSD 223
Cdd:PRK10253  175 DISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTAE 235
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 21-210 1.55e-24

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 97.12  E-value: 1.55e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDShkgfnlPIQQRKIGFVF-----QNYALFPH 94
Cdd:cd03215    19 VSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLdGKPVTRRS------PRDAIRAGIAYvpedrKREGLVLD 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENIIFGHSgdktrieevmalmeldglskkkitaLSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEEL 174
Cdd:cd03215    93 LSVAENIALSSL-------------------------LSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEIYRLI 147

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1238650805 175 KRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:cd03215   148 RELADA-GKAVLLISSELDELLGLCDRILVMYEGRI 182
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 15-231 2.19e-24

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 98.25  E-value: 2.19e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  15 GTFLLQVSL-KLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYfdSHKgfnlPiQQRKIGFVFQNYALFp 93
Cdd:cd03237    11 GEFTLEVEGgSISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTV--SYK----P-QYIKADYEGTVRDLL- 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 hlnvyENIIFGHSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE 173
Cdd:cd03237    83 -----SSITKDFYTHPYFKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKV 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 174 LKRLIAHFGITAFLVSHDLGEVFKLSDEVICLqDGKIAKRGT--PDEVFLS--DRFSAKLQI 231
Cdd:cd03237   158 IRRFAENNEKTAFVVEHDIIMIDYLADRLIVF-EGEPSVNGVanPPQSLRSgmNRFLKNLDI 218
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 20-195 3.70e-24

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 96.66  E-value: 3.70e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfDSHKGFNLPiqQRKIGFVFQNYALFPHLNVYE 99
Cdd:TIGR01189  18 GLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGT---PLAEQRDEP--HENILYLGHLPGLKPELSALE 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NIIFG---HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKR 176
Cdd:TIGR01189  93 NLHFWaaiHGGAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVALLAGLLRA 172

                         170
                  ....*....|....*....
gi 1238650805 177 LIAHFGITAFLVSHDLGEV 195
Cdd:TIGR01189 173 HLARGGIVLLTTHQDLGLV 191
cbiO PRK13642
energy-coupling factor transporter ATPase;
6-220 4.32e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 98.24  E-value: 4.32e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   6 FEKTLDGNHgtfLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVyfDSHKGFNLpiqQRKIGF 84
Cdd:PRK13642   14 YEKESDVNQ---LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIdGELL--TAENVWNL---RRKIGM 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  85 VFQNY-ALFPHLNVYENIIFGHSGDK-------TRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLD 156
Cdd:PRK13642   86 VFQNPdNQFVGATVEDDVAFGMENQGipreemiKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILD 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1238650805 157 EPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKlSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK13642  166 ESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELF 228
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 21-192 4.61e-24

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 101.28  E-value: 4.61e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgNRVYFDSHKGFNLpiqQRKIGFVFQNYALFpHLNVYEN 100
Cdd:TIGR02868 354 VSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTL-DGVPVSSLDQDEV---RRRVSVCAQDAHLF-DTTVREN 428

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFGhSGDKTRiEEVMALME-----------LDGLSKK---KITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:TIGR02868 429 LRLA-RPDATD-EELWAALErvgladwlralPDGLDTVlgeGGARLSGGERQRLALARALLADAPILLLDEPTEHLDAET 506

                         170       180
                  ....*....|....*....|....*.
gi 1238650805 167 RSKLQEELkrLIAHFGITAFLVSHDL 192
Cdd:TIGR02868 507 ADELLEDL--LAALSGRTVVLITHHL 530
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 21-223 1.32e-23

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 100.12  E-value: 1.32e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDkgrIVVGNRVYFDSHKgFNLPIQQRKIGFVFQNYALFPHLNVYEN 100
Cdd:TIGR00955  44 VSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKG---VKGSGSVLLNGMP-IDAKEMRAISAYVQQDDLFIPTLTVREH 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFG-------HSGDKTRIEEVMALMELDGLSK---------KKITALSGGQAQRVALARALASSPDILLLDEPLSALDG 164
Cdd:TIGR00955 120 LMFQahlrmprRVTKKEKRERVDEVLQALGLRKcantrigvpGRVKGLSGGERKRLAFASELLTDPPLLFCDEPTSGLDS 199

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 165 EMRSKLQEELKRLiAHFGITAFLVSHD-LGEVFKLSDEVICLQDGKIAKRGTPDEV--FLSD 223
Cdd:TIGR00955 200 FMAYSVVQVLKGL-AQKGKTIICTIHQpSSELFELFDKIILMAEGRVAYLGSPDQAvpFFSD 260
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 5-222 2.03e-23

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 96.26  E-value: 2.03e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   5 DFEKTLDGnhgtfllqVSLKLPRGKFFSIFGKSGAGKTTILRILSGLeNPDKGRIVVGNRVYFDSHKGF----NLPIQQR 80
Cdd:PRK14258   18 DTQKILEG--------VSMEIYQSKVTAIIGPSGCGKSTFLKCLNRM-NELESEVRVEGRVEFFNQNIYerrvNLNRLRR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  81 KIGFVFQNYALFPhLNVYENIIFGhsgdkTRIEEVMALMELDGLSKKKITA-----------------LSGGQAQRVALA 143
Cdd:PRK14258   89 QVSMVHPKPNLFP-MSVYDNVAYG-----VKIVGWRPKLEIDDIVESALKDadlwdeikhkihksaldLSGGQQQRLCIA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 144 RALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQD-----GKIAKRGTPDE 218
Cdd:PRK14258  163 RALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTKK 242


                  ....
gi 1238650805 219 VFLS 222
Cdd:PRK14258  243 IFNS 246
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 11-224 2.65e-23

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 95.96  E-value: 2.65e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  11 DGNHGtfLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDShkgfNLPIQQRKIGFVFQNY- 89
Cdd:PRK13647   16 DGTKA--LKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAE----NEKWVRSKVGLVFQDPd 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  90 -ALFPhLNVYENIIFGH-----SGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSA 161
Cdd:PRK13647   90 dQVFS-STVWDDVAFGPvnmglDKDevERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAY 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 162 LDGEMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDevFLSDR 224
Cdd:PRK13647  169 LDPRGQETLMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKS--LLTDE 228
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 6-220 2.72e-23

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 99.01  E-value: 2.72e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   6 FEKTLDGNHGtfLLQVSLKLPRGKFFSIFGKSGAGKTT----ILRILsglenPDKGRIvvgnrvYFDSH--KGFN----L 75
Cdd:PRK15134  292 LKRTVDHNVV--VKNISFTLRPGETLGLVGESGSGKSTtglaLLRLI-----NSQGEI------WFDGQplHNLNrrqlL 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  76 PIQqRKIGFVFQ--NYALFPHLNVYENIIFG---HSGDKT---RIEEVMALME---LDGLSKKKI-TALSGGQAQRVALA 143
Cdd:PRK15134  359 PVR-HRIQVVFQdpNSSLNPRLNVLQIIEEGlrvHQPTLSaaqREQQVIAVMEevgLDPETRHRYpAEFSGGQRQRIAIA 437

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 144 RALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK15134  438 RALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVF 514
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 21-224 2.73e-23

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 95.35  E-value: 2.73e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfDSHKGFNLPIQQRK---IGFVFQNYALFPHLNV 97
Cdd:PRK10895   22 VSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIII------DDEDISLLPLHARArrgIGYLPQEASIFRRLSV 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENII--------FGHSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGemRSK 169
Cdd:PRK10895   96 YDNLMavlqirddLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDP--ISV 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 170 LqeELKRLIAHF---GITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDR 224
Cdd:PRK10895  174 I--DIKRIIEHLrdsGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEH 229
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
18-210 3.07e-23

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 99.03  E-value: 3.07e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKG--RIVVGNRVYFDSHKgfnLPIQQRK-IGFVFQNYALFPH 94
Cdd:PRK10535   24 LKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGtyRVAGQDVATLDADA---LAQLRREhFGFIFQRYHLLSH 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENI----IFGHSGDKTRIEEVMALMELDGLSKK---KITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMR 167
Cdd:PRK10535  101 LTAAQNVevpaVYAGLERKQRLLRAQELLQRLGLEDRveyQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSG 180

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1238650805 168 SKLQEELKRLIAHfGITAFLVSHDlGEVFKLSDEVICLQDGKI 210
Cdd:PRK10535  181 EEVMAILHQLRDR-GHTVIIVTHD-PQVAAQAERVIEIRDGEI 221
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
16-240 6.04e-23

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 94.85  E-value: 6.04e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  16 TFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFD-SHKGFnlpiqQRKIGFVFQNYALFPH 94
Cdd:PRK10575   25 TLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAF-----ARKVAYLPQQLPAAEG 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENIIFGH-----------SGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALD 163
Cdd:PRK10575  100 MTVRELVAIGRypwhgalgrfgAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALD 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 164 GEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSaklQINGEILKITP 240
Cdd:PRK10575  180 IAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGETLE---QIYGIPMGILP 253
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 21-220 6.57e-23

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 97.90  E-value: 6.57e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRivvgnrVYFDSHKGFNLPIQQ--RKIGFVFQNYALFPHlNVY 98
Cdd:COG4618   351 VSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGS------VRLDGADLSQWDREElgRHIGYLPQDVELFDG-TIA 423

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENII-FG----------------H-------SGDKTRIEEvmalmelDGlskkkiTALSGGQAQRVALARALASSPDILL 154
Cdd:COG4618   424 ENIArFGdadpekvvaaaklagvHemilrlpDGYDTRIGE-------GG------ARLSGGQRQRIGLARALYGDPRLVV 490

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 155 LDEPLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLGeVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:COG4618   491 LDEPNSNLDDEGEAALAAAIRALKAR-GATVVVITHRPS-LLAAVDKLLVLRDGRVQAFGPRDEVL 554
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 21-243 1.45e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 94.10  E-value: 1.45e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDshkgfNLPIQQRKIGFVFQNY--ALFPHlNV 97
Cdd:PRK13652   23 INFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIrGEPITKE-----NIREVRKFVGLVFQNPddQIFSP-TV 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFG-------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:PRK13652   97 EQDIAFGpinlgldEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKEL 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 171 QEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSAKLQINGEILKITPQSL 243
Cdd:PRK13652  177 IDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQPDLLARVHLDLPSLPKLIRSL 249
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
21-220 1.47e-22

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 94.30  E-value: 1.47e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFnLPIQQrKIGFVFQN--YALFpHLNVY 98
Cdd:PRK13638   20 LNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKRGL-LALRQ-QVATVFQDpeQQIF-YTDID 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENIIF-----GHSGDKT--RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQ 171
Cdd:PRK13638   97 SDIAFslrnlGVPEAEItrRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMI 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1238650805 172 EELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK13638  177 AIIRRIVAQ-GNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVF 224
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 21-219 2.21e-22

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 93.36  E-value: 2.21e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYfDSHKGFNLPIQQRKI------GFVFQNYA---- 90
Cdd:TIGR02323  22 VSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRSG-AELELYQLSEAERRRlmrtewGFVHQNPRdglr 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 --LFPHLNVYENII-FG--HSGDkTRIEEVMALMELD---GLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSAL 162
Cdd:TIGR02323 101 mrVSAGANIGERLMaIGarHYGN-IRATAQDWLEEVEidpTRIDDLPRAFSGGMQQRLQIARNLVTRPRLVFMDEPTGGL 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 163 DGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:TIGR02323 180 DVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESGLTDQV 236
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 1-190 3.91e-22

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 91.16  E-value: 3.91e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   1 MIELDFektlDGNHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrVYFDSHKGFNLPIQQR 80
Cdd:PRK13540    4 VIELDF----DYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEI-----LFERQSIKKDLCTYQK 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  81 KIGFVFQNYALFPHLNVYENIIFG--HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEP 158
Cdd:PRK13540   75 QLCFVGHRSGINPYLTLRENCLYDihFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEP 154

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1238650805 159 LSALDGE----MRSKLQEELKRliahfGITAFLVSH 190
Cdd:PRK13540  155 LVALDELslltIITKIQEHRAK-----GGAVLLTSH 185
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 18-219 1.03e-21

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 94.72  E-value: 1.03e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVG-------NRVYFDSHkgfnlpiqqrkIGFVFQNYA 90
Cdd:TIGR01842 334 LRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDgadlkqwDRETFGKH-----------IGYLPQDVE 402

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPHlNVYENIifGHSGDKTRIEEVMALMELDGLSKKKI--------------TALSGGQAQRVALARALASSPDILLLD 156
Cdd:TIGR01842 403 LFPG-TVAENI--ARFGENADPEKIIEAAKLAGVHELILrlpdgydtvigpggATLSGGQRQRIALARALYGDPKLVVLD 479

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 157 EPLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLGeVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:TIGR01842 480 EPNSNLDEEGEQALANAIKALKAR-GITVVVITHRPS-LLGCVDKILVLQDGRIARFGERDEV 540
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 18-227 1.61e-21

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 90.94  E-value: 1.61e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGnrvyfdshkgfnlpiQQRKIGFVFQNYALFPH--L 95
Cdd:PRK09544   20 LSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRN---------------GKLRIGYVPQKLYLDTTlpL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  96 NVYENIIFGHSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELK 175
Cdd:PRK09544   85 TVNRFLRLRPGTKKEDILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYDLID 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 176 RLIAHFGITAFLVSHDLGEVFKLSDEVICLqDGKIAKRGTPDEVFLSDRFSA 227
Cdd:PRK09544  165 QLRRELDCAVLMVSHDLHLVMAKTDEVLCL-NHHICCSGTPEVVSLHPEFIS 215
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 21-219 1.77e-21

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 90.76  E-value: 1.77e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNR--VYFDShkgFNLPIQQRKI------GFVFQNYA-- 90
Cdd:PRK11701   25 VSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRdgQLRDL---YALSEAERRRllrtewGFVHQHPRdg 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPHLNVYENIifghsGdktriEEVMALME----------LDGLSKKKI---------TALSGGQAQRVALARALASSPD 151
Cdd:PRK11701  102 LRMQVSAGGNI-----G-----ERLMAVGArhygdirataGDWLERVEIdaariddlpTTFSGGMQQRLQIARNLVTHPR 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 152 ILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:PRK11701  172 LVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESGLTDQV 239
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
18-215 1.78e-21

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 93.93  E-value: 1.78e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfDSH--KGFNLPIQQRKIGFVFQNYALFpHL 95
Cdd:PRK11176  359 LRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILL------DGHdlRDYTLASLRNQVALVSQNVHLF-ND 431

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  96 NVYENIIFGHSGDKTR--IEEV--MA-LME--------LDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSAL 162
Cdd:PRK11176  432 TIANNIAYARTEQYSReqIEEAarMAyAMDfinkmdngLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSAL 511

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 163 DGEMRSKLQ---EELKRliahfGITAFLVSHDLGEVFKlSDEVICLQDGKIAKRGT 215
Cdd:PRK11176  512 DTESERAIQaalDELQK-----NRTSLVIAHRLSTIEK-ADEILVVEDGEIVERGT 561
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 21-191 3.49e-21

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 93.08  E-value: 3.49e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVyfdshkgfnlpiqqrKIGFVFQNY-ALFPHLNVYE 99
Cdd:TIGR03719 341 LSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIGETV---------------KLAYVDQSRdALDPNKTVWE 405

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NIIFGHsgDKTRI--EEVMALMELDGLS------KKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQ 171
Cdd:TIGR03719 406 EISGGL--DIIKLgkREIPSRAYVGRFNfkgsdqQKKVGQLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDVETLRALE 483

                         170       180
                  ....*....|....*....|
gi 1238650805 172 EELKrliaHFGITAFLVSHD 191
Cdd:TIGR03719 484 EALL----NFAGCAVVISHD 499
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 15-218 3.79e-21

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 92.99  E-value: 3.79e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  15 GTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLEnPDKGRIVVgNRVYFDShkgFNLPIQQRKIGFVFQNYALFp 93
Cdd:PRK11174  362 GKTLAGpLNFTLPAGQRIALVGPSGAGKTSLLNALLGFL-PYQGSLKI-NGIELRE---LDPESWRKHLSWVGQNPQLP- 435

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 HLNVYENIIFG-HSGDKTRIEEVMALMEL--------DGLS---KKKITALSGGQAQRVALARALASSPDILLLDEPLSA 161
Cdd:PRK11174  436 HGTLRDNVLLGnPDASDEQLQQALENAWVseflpllpQGLDtpiGDQAAGLSVGQAQRLALARALLQPCQLLLLDEPTAS 515

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 162 LDGEMRSKLQEELKRliAHFGITAFLVSHDLgEVFKLSDEVICLQDGKIAKRGTPDE 218
Cdd:PRK11174  516 LDAHSEQLVMQALNA--ASRRQTTLMVTHQL-EDLAQWDQIWVMQDGQIVQQGDYAE 569
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 21-218 5.17e-21

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 92.42  E-value: 5.17e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYfdshkgFNL-PIQQRKIG--FVFQNYALFPHLNV 97
Cdd:PRK15439   30 IDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPC------ARLtPAKAHQLGiyLVPQEPLLFPNLSV 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFG---HSGDKTRIEEVMALM----ELDglskKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:PRK15439  104 KENILFGlpkRQASMQKMKQLLAALgcqlDLD----SSAGSLEVADRQIVEILRGLMRDSRILILDEPTASLTPAETERL 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1238650805 171 QEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDE 218
Cdd:PRK15439  180 FSRIRELLAQ-GVGIVFISHKLPEIRQLADRISVMRDGTIALSGKTAD 226
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 21-211 7.98e-21

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 88.48  E-value: 7.98e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDK---GRIVVGNRvyfDSHKGfnlpIQQRKIGFVFQNYALFPHLNV 97
Cdd:cd03234    26 VSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGttsGQILFNGQ---PRKPD----QFQKCVAYVRQDDILLPGLTV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFG-------HSGDKTR--IEEVMALMELdGLSK---KKITALSGGQAQRVALARALASSPDILLLDEPLSALDGE 165
Cdd:cd03234    99 RETLTYTailrlprKSSDAIRkkRVEDVLLRDL-ALTRiggNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSF 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1238650805 166 MRSKLQEELKRLiAHFGITAFLVSHDLG-EVFKLSDEVICLQDGKIA 211
Cdd:cd03234   178 TALNLVSTLSQL-ARRNRIVILTIHQPRsDLFRLFDRILLLSSGEIV 223
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 22-218 2.72e-20

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 90.55  E-value: 2.72e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  22 SLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNR--VYFDSHkgfnlpIQQRKIGFVFQNYALFPHlNVYE 99
Cdd:TIGR00958 501 TFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVplVQYDHH------YLHRQVALVGQEPVLFSG-SVRE 573

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NIIFGHsgDKTRIEEVMA----------LMEL----DGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGE 165
Cdd:TIGR00958 574 NIAYGL--TDTPDEEIMAaakaanahdfIMEFpngyDTEVGEKGSQLSGGQKQRIAIARALVRKPRVLILDEATSALDAE 651

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 166 MRSKLQEELKRliahFGITAFLVSHDLGEVFKlSDEVICLQDGKIAKRGTPDE 218
Cdd:TIGR00958 652 CEQLLQESRSR----ASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQ 699
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 8-220 3.93e-20

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 88.61  E-value: 3.93e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   8 KTLDGnhgtfllqVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIV-VGNRVYFDSHKGFNlpiQQRK-IGFV 85
Cdd:PRK15079   35 KAVDG--------VTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAwLGKDLLGMKDDEWR---AVRSdIQMI 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  86 FQN--YALFPHLNVYEnII-------FGHSGDKTRIEEVMALMELDGLSKKKIT----ALSGGQAQRVALARALASSPDI 152
Cdd:PRK15079  104 FQDplASLNPRMTIGE-IIaeplrtyHPKLSRQEVKDRVKAMMLKVGLLPNLINryphEFSGGQCQRIGIARALILEPKL 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 153 LLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK15079  183 IICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVY 250
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 18-210 7.17e-20

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 85.99  E-value: 7.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfDSHkgfnlPIQQ-------RKIGFVFQNYA 90
Cdd:cd03248    30 LQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLL------DGK-----PISQyehkylhSKVSLVGQEPV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPHlNVYENIIFGHSGDKTriEEVMA----------LMEL-DGLSK---KKITALSGGQAQRVALARALASSPDILLLD 156
Cdd:cd03248    99 LFAR-SLQDNIAYGLQSCSF--ECVKEaaqkahahsfISELaSGYDTevgEKGSQLSGGQKQRVAIARALIRNPQVLILD 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1238650805 157 EPLSALDGEMRSKLQEELKRliAHFGITAFLVSHDLGEVFKlSDEVICLQDGKI 210
Cdd:cd03248   176 EATSALDAESEQQVQQALYD--WPERRTVLVIAHRLSTVER-ADQILVLDGGRI 226
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
21-227 8.15e-20

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 89.25  E-value: 8.15e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVyfdshKGFNLPIQQRKIGFVFQNYALFpHLNVYE 99
Cdd:PRK13657  354 VSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIdGTDI-----RTVTRASLRRNIAVVFQDAGLF-NRSIED 427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NIIFGHSgDKTRiEEVMALME--------------LDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGE 165
Cdd:PRK13657  428 NIRVGRP-DATD-EEMRAAAEraqahdfierkpdgYDTVVGERGRQLSGGERQRLAIARALLKDPPILILDEATSALDVE 505

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 166 MRSKLQEELKRLIAhfGITAFLVSHDLGEVfKLSDEVICLQDGKIAKRGTPDE-VFLSDRFSA 227
Cdd:PRK13657  506 TEAKVKAALDELMK--GRTTFIIAHRLSTV-RNADRILVFDNGRVVESGSFDElVARGGRFAA 565
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 32-225 1.07e-19

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 89.30  E-value: 1.07e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   32 SIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfDSHKgfNLPIQQRKIGFVFQNYALFPHLNVYENIIF-----GHS 106
Cdd:TIGR01257  960 AFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGK---DIET--NLDAVRQSLGMCPQHNILFHHLTVAEHILFyaqlkGRS 1034

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  107 GDKTRIeEVMALMELDGLSKKK---ITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELkrLIAHFGI 183
Cdd:TIGR01257 1035 WEEAQL-EMEAMLEDTGLHHKRneeAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLL--LKYRSGR 1111

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1238650805  184 TAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPdeVFLSDRF 225
Cdd:TIGR01257 1112 TIIMSTHHMDEADLLGDRIAIISQGRLYCSGTP--LFLKNCF 1151
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
5-215 1.79e-19

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 87.94  E-value: 1.79e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   5 DFEKTLDGnhgtFLLQVSL-KLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVyfdSHK------GFNLPI 77
Cdd:PRK13409  345 DLTKKLGD----FSLEVEGgEIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELKI---SYKpqyikpDYDGTV 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  78 QQ--RKIGFVFQNyalfphlNVYENiifghsgdktrieEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLL 155
Cdd:PRK13409  418 EDllRSITDDLGS-------SYYKS-------------EIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLL 477

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 156 DEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLqDGKIAKRGT 215
Cdd:PRK13409  478 DEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHDIYMIDYISDRLMVF-EGEPGKHGH 536
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 20-180 2.09e-19

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 84.16  E-value: 2.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHkgfnLPIQQRKIGFvfQNyALFPHLNVYE 99
Cdd:PRK13539   20 GLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPD----VAEACHYLGH--RN-AMKPALTVAE 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 100 NIIFG---HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDgemrSKLQEELKR 176
Cdd:PRK13539   93 NLEFWaafLGGEELDIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALD----AAAVALFAE 168


                  ....
gi 1238650805 177 LIAH 180
Cdd:PRK13539  169 LIRA 172
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
21-219 2.38e-19

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 87.38  E-value: 2.38e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDShkgfnlPIQQRKIGFVF-----QNYALFPH 94
Cdd:COG1129   271 VSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLdGKPVRIRS------PRDAIRAGIAYvpedrKGEGLVLD 344

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENII------FGHSG--DKTRIEEVMALMeLDGLS------KKKITALSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:COG1129   345 LSIRENITlasldrLSRGGllDRRRERALAEEY-IKRLRiktpspEQPVGNLSGGNQQKVVLAKWLATDPKVLILDEPTR 423

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 161 ALDgeMRSKlqEELKRLIAHF---GITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:COG1129   424 GID--VGAK--AEIYRLIRELaaeGKAVIVISSELPELLGLSDRILVMREGRIVGELDREEA 481
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
18-209 3.27e-19

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 87.27  E-value: 3.27e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDS-----HKGfnlpiqqrkIGFVFQNYAL 91
Cdd:PRK11288   20 LDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIdGQEMRFASttaalAAG---------VAIIYQELHL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  92 FPHLNVYENIIFGH----SG---DKTRIEEVMALMELDGLS---KKKITALSGGQAQRVALARALASSPDILLLDEPLSA 161
Cdd:PRK11288   91 VPEMTVAENLYLGQlphkGGivnRRLLNYEAREQLEHLGVDidpDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSS 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 162 LDgemrSKLQEELKRLIAHF---GITAFLVSHDLGEVFKLSDEVICLQDGK 209
Cdd:PRK11288  171 LS----AREIEQLFRVIRELraeGRVILYVSHRMEEIFALCDAITVFKDGR 217
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
21-222 3.67e-19

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 84.84  E-value: 3.67e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNR--VYFDSHkgfnlpIQQRKIGFVFQNYAlfPHLNVY 98
Cdd:PRK15112   32 LSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHplHFGDYS------YRSQRIRMIFQDPS--TSLNPR 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENIifGHSGD-----------KTRIEEVMALMELDGLSKKKIT----ALSGGQAQRVALARALASSPDILLLDEPLSALD 163
Cdd:PRK15112  104 QRI--SQILDfplrlntdlepEQREKQIIETLRQVGLLPDHASyyphMLAPGQKQRLGLARALILRPKVIIADEALASLD 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805 164 GEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLS 222
Cdd:PRK15112  182 MSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLAS 240
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 8-209 3.88e-19

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 86.91  E-value: 3.88e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   8 KTLDGnhgtfllqVSLKLPRGKFFSIFGKSGAGKTTILRILSGLEnPD---KGRIvvgnrvYFDSH--KGFNLPIQQRK- 81
Cdd:PRK13549   19 KALDN--------VSLKVRAGEIVSLCGENGAGKSTLMKVLSGVY-PHgtyEGEI------IFEGEelQASNIRDTERAg 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  82 IGFVFQNYALFPHLNVYENIIFGHSGDK----------TRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPD 151
Cdd:PRK13549   84 IAIIHQELALVKELSVLENIFLGNEITPggimdydamyLRAQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNKQAR 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 152 ILLLDEPLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGK 209
Cdd:PRK13549  164 LLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGR 220
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 5-215 8.11e-19

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 85.99  E-value: 8.11e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   5 DFEKTLDGnhgtFLLQV-SLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVyfdSHKgfnlPiQQRKIG 83
Cdd:COG1245   346 DLTKSYGG----FSLEVeGGEIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLKI---SYK----P-QYISPD 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  84 FvfqnyalfpHLNVYEnIIFGHSGDKTR----IEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:COG1245   414 Y---------DGTVEE-FLRSANTDDFGssyyKTEIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPS 483

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805 160 SALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLqDGKIAKRGT 215
Cdd:COG1245   484 AHLDVEQRLAVAKAIRRFAENRGKTAMVVDHDIYLIDYISDRLMVF-EGEPGVHGH 538
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 18-244 8.16e-19

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 83.35  E-value: 8.16e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLEnPDKGRIVVGNRVYFD-------SHKGFnLPIQQRKIGF--VFQN 88
Cdd:COG4138    12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLNGRPLSDwsaaelaRHRAY-LSQQQSPPFAmpVFQY 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  89 YALFPHLNVyeniifGHSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARAL-----ASSPD--ILLLDEPLSA 161
Cdd:COG4138    90 LALHQPAGA------SSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLlqvwpTINPEgqLLLLDEPMNS 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 162 LDGEMRSKLQeelkRLIAHF---GITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSAKLQINGEILKI 238
Cdd:COG4138   164 LDVAQQAALD----RLLRELcqqGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMTPENLSEVFGVKFRRLEV 239


                  ....*.
gi 1238650805 239 TPQSLI 244
Cdd:COG4138   240 EGHRWL 245
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
18-210 1.01e-18

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 83.00  E-value: 1.01e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVvgnrvyFDSHKGFNLP---IQQRKIGFVFQNYALFPH 94
Cdd:PRK11614   21 LHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIV------FDGKDITDWQtakIMREAVAIVPEGRRVFSR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENIIFG-----HSGDKTRIEEVMALM-ELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRS 168
Cdd:PRK11614   95 MTVEENLAMGgffaeRDQFQERIKWVYELFpRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQ 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1238650805 169 KLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:PRK11614  175 QIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHV 215
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 15-244 1.03e-18

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 83.06  E-value: 1.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  15 GTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLeNPDKGRIVVGN--------------RVYFdshkgfnlpIQQR 80
Cdd:PRK03695    9 STRLGPLSAEVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGqpleawsaaelarhRAYL---------SQQQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  81 KIGF---VFQNYALFPHLNVYEniifghSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARA-LASSPDI---- 152
Cdd:PRK03695   79 TPPFampVFQYLTLHQPDKTRT------EAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVvLQVWPDInpag 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 153 --LLLDEPLSALDGEMrsklQEELKRLIAHF---GITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSA 227
Cdd:PRK03695  153 qlLLLDEPMNSLDVAQ----QAALDRLLSELcqqGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPENLAQ 228

                         250
                  ....*....|....*..
gi 1238650805 228 KLQINGEILKITPQSLI 244
Cdd:PRK03695  229 VFGVNFRRLDVEGHPML 245
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 20-220 1.36e-18

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 85.68  E-value: 1.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVyfDSHKGFNLPIQQRKIGFVFQN-YA-LFPHLN 96
Cdd:PRK10261  342 KVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFnGQRI--DTLSPGKLQALRRDIQFIFQDpYAsLDPRQT 419

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 VYENI-----IFGHSGDKTRIEEVMALMELDGLSKKKI----TALSGGQAQRVALARALASSPDILLLDEPLSALDGEMR 167
Cdd:PRK10261  420 VGDSImeplrVHGLLPGKAAAARVAWLLERVGLLPEHAwrypHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIR 499

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 168 SKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK10261  500 GQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVF 552
GguA NF040905
sugar ABC transporter ATP-binding protein;
18-209 1.54e-18

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 85.23  E-value: 1.54e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGL------EnpdkGRIVV-GNRVYF----DShkgfnlpiQQRKIGFVF 86
Cdd:NF040905   17 LDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVyphgsyE----GEILFdGEVCRFkdirDS--------EALGIVIIH 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  87 QNYALFPHLNVYENIIFGHSGDK----------TRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLD 156
Cdd:NF040905   85 QELALIPYLSIAENIFLGNERAKrgvidwnetnRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLILD 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 157 EPLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGK 209
Cdd:NF040905  165 EPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGR 216
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 22-191 2.33e-18

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 84.79  E-value: 2.33e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  22 SLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVyfdshkgfnlpiqqrKIGFVFQNY-ALFPHLNVYEN 100
Cdd:PRK11819  344 SFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIGETV---------------KLAYVDQSRdALDPNKTVWEE 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFGHsgdktrieEVMALMELDGLSK--------------KKITALSGGQAQRVALARALASSPDILLLDEPLSALDGE- 165
Cdd:PRK11819  409 ISGGL--------DIIKVGNREIPSRayvgrfnfkggdqqKKVGVLSGGERNRLHLAKTLKQGGNVLLLDEPTNDLDVEt 480

                         170       180
                  ....*....|....*....|....*.
gi 1238650805 166 MRSkLQEELkrliAHFGITAFLVSHD 191
Cdd:PRK11819  481 LRA-LEEAL----LEFPGCAVVISHD 501
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 5-209 2.62e-18

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 79.41  E-value: 2.62e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   5 DFEKTLDGNhgTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVyfdshkgfnlpiqqrKIGF 84
Cdd:cd03221     5 NLSKTYGGK--LLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTV---------------KIGY 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  85 VFQnyalfphlnvyeniifghsgdktrieevmalmeldglskkkitaLSGGQAQRVALARALASSPDILLLDEPLSALDG 164
Cdd:cd03221    68 FEQ--------------------------------------------LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDL 103

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1238650805 165 EMRSKLQEELKRliahFGITAFLVSHDLGEVFKLSDEVICLQDGK 209
Cdd:cd03221   104 ESIEALEEALKE----YPGTVILVSHDRYFLDQVATKIIELEDGK 144
PTZ00243 PTZ00243
ABC transporter; Provisional
 18-214 3.50e-18

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 84.45  E-value: 3.50e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfdshkgfnlpiqQRKIGFVFQNyALFPHLNV 97
Cdd:PTZ00243   676 LRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVWA-----------------ERSIAYVPQQ-AWIMNATV 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   98 YENIIFGHSGDKTRIEEVMALMELD--------GLSKK---KITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:PTZ00243   738 RGNILFFDEEDAARLADAVRVSQLEadlaqlggGLETEigeKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHV 817

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1238650805  167 RSKLQEELkRLIAHFGITAFLVSHDLgEVFKLSDEVICLQDGKIAKRG 214
Cdd:PTZ00243   818 GERVVEEC-FLGALAGKTRVLATHQV-HVVPRADYVVALGDGRVEFSG 863
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 18-229 6.42e-18

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 83.64  E-value: 6.42e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGfnlpIQQRKIGFVFQNYALFPHlNV 97
Cdd:TIGR01193 490 LSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRH----TLRQFINYLPQEPYIFSG-SI 564

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFGhSGDKTRIEEVMALMELDGLsKKKI---------------TALSGGQAQRVALARALASSPDILLLDEPLSAL 162
Cdd:TIGR01193 565 LENLLLG-AKENVSQDEIWAACEIAEI-KDDIenmplgyqtelseegSSISGGQKQRIALARALLTDSKVLILDESTSNL 642

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 163 DGEMRSKLQEELKRLIAHfgiTAFLVSHDLgEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSAKL 229
Cdd:TIGR01193 643 DTITEKKIVNNLLNLQDK---TIIFVAHRL-SVAKQSDKIIVLDHGKIIEQGSHDELLDRNGFYASL 705
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 21-250 7.36e-18

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 83.34  E-value: 7.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGL--ENPDKGRIvvgnrvYFDSH--KGFNLPIQQRK-IGFVFQNYALFPHL 95
Cdd:TIGR02633  20 IDLEVRPGECVGLCGENGAGKSTLMKILSGVypHGTWDGEI------YWSGSplKASNIRDTERAgIVIIHQELTLVPEL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  96 NVYENIIFG----HSGDKT-------RIEEVMALMELDGLS-KKKITALSGGQAQRVALARALASSPDILLLDEPLSALD 163
Cdd:TIGR02633  94 SVAENIFLGneitLPGGRMaynamylRAKNLLRELQLDADNvTRPVGDYGGGQQQLVEIAKALNKQARLLILDEPSSSLT 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 164 GEMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKiaKRGTPDEVFLSDRFSAKLQINGEILKITPQSL 243
Cdd:TIGR02633 174 EKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQ--HVATKDMSTMSEDDIITMMVGREITSLYPHEP 250


                  ....*..
gi 1238650805 244 ITIVDVL 250
Cdd:TIGR02633 251 HEIGDVI 257
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
13-223 2.14e-17

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 79.93  E-value: 2.14e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  13 NHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRI-VVGNRVyfdshkgfNLPIQQRKIGFVFQNYAL 91
Cdd:PRK15056   18 NGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKIsILGQPT--------RQALQKNLVAYVPQSEEV 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  92 ---FPHLnvYENII----FGHSG--------DKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLD 156
Cdd:PRK15056   90 dwsFPVL--VEDVVmmgrYGHMGwlrrakkrDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLD 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1238650805 157 EPLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQdGKIAKRGTPDEVFLSD 223
Cdd:PRK15056  168 EPFTGVDVKTEARIISLLRELRDE-GKTMLVSTHNLGSVTEFCDYTVMVK-GTVLASGPTETTFTAE 232
hmuV PRK13547
heme ABC transporter ATP-binding protein;
14-219 2.15e-17

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 79.87  E-value: 2.15e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  14 HGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGlENPDKGR---IVVGNRVYFDSHKGFNLPI-----------QQ 79
Cdd:PRK13547   13 HRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAG-DLTGGGAprgARVTGDVTLNGEPLAAIDAprlarlravlpQA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  80 RKIGFVFQNYAL-----FPHLNvyeniifgHSGDKTR-----IEEVMALMELDGLSKKKITALSGGQAQRVALARALA-- 147
Cdd:PRK13547   92 AQPAFAFSAREIvllgrYPHAR--------RAGALTHrdgeiAWQALALAGATALVGRDVTTLSGGELARVQFARVLAql 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805 148 -------SSPDILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:PRK13547  164 wpphdaaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADV 242
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 8-213 2.65e-17

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 81.59  E-value: 2.65e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   8 KTLDGnhgtfllqVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIV-VGNRVYFDSHKGfnlpIQQRKIGFVF 86
Cdd:PRK10762   18 KALSG--------AALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILyLGKEVTFNGPKS----SQEAGIGIIH 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  87 QNYALFPHLNVYENIIFGHSGDKT--RIEEVMALMELDGL---------SKKKITALSGGQAQRVALARALASSPDILLL 155
Cdd:PRK10762   86 QELNLIPQLTIAENIFLGREFVNRfgRIDWKKMYAEADKLlarlnlrfsSDKLVGELSIGEQQMVEIAKVLSFESKVIIM 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 156 DEPLSAL-DGEMRS--KLQEELKRliAHFGITafLVSHDLGEVFKLSDEVICLQDGK-IAKR 213
Cdd:PRK10762  166 DEPTDALtDTETESlfRVIRELKS--QGRGIV--YISHRLKEIFEICDDVTVFRDGQfIAER 223
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 21-223 5.61e-17

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 81.15  E-value: 5.61e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKG------------FNLPIQQRKIGFVFQN 88
Cdd:TIGR00957  657 ITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGSVAYVPQQAwiqndslrenilFGKALNEKYYQQVLEA 736

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   89 YALFPHLNVYEniifghSGDKTRIEEvmalmeldglskkKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRS 168
Cdd:TIGR00957  737 CALLPDLEILP------SGDRTEIGE-------------KGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGK 797

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805  169 KLQEEL---KRLIAhfGITAFLVSHDLgEVFKLSDEVICLQDGKIAKRGTPDEVFLSD 223
Cdd:TIGR00957  798 HIFEHVigpEGVLK--NKTRILVTHGI-SYLPQVDVIIVMSGGKISEMGSYQELLQRD 852
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 3-174 5.92e-17

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 80.62  E-value: 5.92e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   3 ELDFEK-TLDGNHGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV--GNRVYFdshkgfnLPiq 78
Cdd:COG4178   362 ALALEDlTLRTPDGRPLLEdLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARpaGARVLF-------LP-- 432

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  79 QRkigfvfqNYalFPHLNVYENIIFGHSGDK---TRIEEVMALMELDGLSKK--------KItaLSGGQAQRVALARALA 147
Cdd:COG4178   433 QR-------PY--LPLGTLREALLYPATAEAfsdAELREALEAVGLGHLAERldeeadwdQV--LSLGEQQRLAFARLLL 501

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1238650805 148 SSPDILLLDEPLSALDGE----MRSKLQEEL 174
Cdd:COG4178   502 HKPDWLFLDEATSALDEEneaaLYQLLREEL 532
PLN03232 PLN03232
ABC transporter C family member; Provisional
 18-232 7.45e-17

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 80.79  E-value: 7.45e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSG-LENPDKGRIVVGNRVYFdshkgfnLPiqqrKIGFVFqnyalfpHLN 96
Cdd:PLN03232   633 LSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGeLSHAETSSVVIRGSVAY-------VP----QVSWIF-------NAT 694

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   97 VYENIIFGHSGDKTRIE---EVMALM-ELDGLSKKKITAL-------SGGQAQRVALARALASSPDILLLDEPLSALDGE 165
Cdd:PLN03232   695 VRENILFGSDFESERYWraiDVTALQhDLDLLPGRDLTEIgergvniSGGQKQRVSMARAVYSNSDIYIFDDPLSALDAH 774

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1238650805  166 M-----RSKLQEELKrliahfGITAFLVSHDLgEVFKLSDEVICLQDGKIAKRGTPDEVFLSDRFSAKLQIN 232
Cdd:PLN03232   775 VahqvfDSCMKDELK------GKTRVLVTNQL-HFLPLMDRIILVSEGMIKEEGTFAELSKSGSLFKKLMEN 839
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 33-191 9.74e-17

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 79.98  E-value: 9.74e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  33 IFGKSGAGKTTILRILSGLENPDKGRIVvgnrvyfdshkgfnlPIQQRKIGFVFQNYALFPHLNVYENIIFGHSGDK--- 109
Cdd:TIGR03719  36 VLGLNGAGKSTLLRIMAGVDKDFNGEAR---------------PQPGIKVGYLPQEPQLDPTKTVRENVEEGVAEIKdal 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 110 TRIEEVMALM-----ELDGLSKK----------------------------------KITALSGGQAQRVALARALASSP 150
Cdd:TIGR03719 101 DRFNEISAKYaepdaDFDKLAAEqaelqeiidaadawdldsqleiamdalrcppwdaDVTKLSGGERRRVALCRLLLSKP 180

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1238650805 151 DILLLDEPLSALDGEMRSKLQEELKRliahFGITAFLVSHD 191
Cdd:TIGR03719 181 DMLLLDEPTNHLDAESVAWLERHLQE----YPGTVVAVTHD 217
PLN03211 PLN03211
ABC transporter G-25; Provisional
 28-209 2.48e-16

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 78.77  E-value: 2.48e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  28 GKFFSIFGKSGAGKTTILRILSGL--ENPDKGRIVVGNRVyfdshkgfnlPIQQ--RKIGFVFQNYALFPHLNVYENIIF 103
Cdd:PLN03211   94 GEILAVLGPSGSGKSTLLNALAGRiqGNNFTGTILANNRK----------PTKQilKRTGFVTQDDILYPHLTVRETLVF 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 104 GH---------SGDKTRIEEVMaLMELdGLSKKK--------ITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:PLN03211  164 CSllrlpksltKQEKILVAESV-ISEL-GLTKCEntiignsfIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATA 241

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1238650805 167 RSKLQEELKRLiAHFGITAFLVSHD-LGEVFKLSDEVICLQDGK 209
Cdd:PLN03211  242 AYRLVLTLGSL-AQKGKTIVTSMHQpSSRVYQMFDSVLVLSEGR 284
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 18-208 2.67e-16

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 75.83  E-value: 2.67e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRKIGFVFQNYALFpHLNV 97
Cdd:cd03290    17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRYSVAYAAQKPWLL-NATV 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFGHSGDKTRIEEVMALMELD------------GLSKKKITaLSGGQAQRVALARALASSPDILLLDEPLSALDGE 165
Cdd:cd03290    96 EENITFGSPFNKQRYKAVTDACSLQpdidllpfgdqtEIGERGIN-LSGGQRQRICVARALYQNTNIVFLDDPFSALDIH 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1238650805 166 MRSKL-QEELKRLIAHFGITAFLVSHDLgEVFKLSDEVICLQDG 208
Cdd:cd03290   175 LSDHLmQEGILKFLQDDKRTLVLVTHKL-QYLPHADWIIAMKDG 217
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 9-214 3.60e-16

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 74.66  E-value: 3.60e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   9 TLDGNHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvYFDSHKGFNLPIQQRK-IGFVFQ 87
Cdd:cd03247     9 SYPEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEI------TLDGVPVSDLEKALSSlISVLNQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  88 NyalfPHL---NVYENIifghsgdktrieevmalmeldGlskkkiTALSGGQAQRVALARALASSPDILLLDEPLSALDg 164
Cdd:cd03247    83 R----PYLfdtTLRNNL---------------------G------RRFSGGERQRLALARILLQDAPIVLLDEPTVGLD- 130

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 165 emrSKLQEELKRLIAHF--GITAFLVSHDLGEVFKLsDEVICLQDGKIAKRG 214
Cdd:cd03247   131 ---PITERQLLSLIFEVlkDKTLIWITHHLTGIEHM-DKILFLENGKIIMQG 178
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 14-229 4.01e-16

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 78.41  E-value: 4.01e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   14 HGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRkigfvfqnyalf 92
Cdd:TIGR01271  437 YVTPVLKnISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGRISFSPQTSWIMPGTIK------------ 504

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   93 phlnvyENIIFGHSGDKTRIEEVMALMELDG------------LSKKKITaLSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:TIGR01271  505 ------DNIIFGLSYDEYRYTSVIKACQLEEdialfpekdktvLGEGGIT-LSGGQRARISLARAVYKDADLYLLDSPFT 577

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805  161 ALDGEMRSKLQEE-LKRLIAHfgITAFLVSHDLgEVFKLSDEVICLQDGKIAKRGTPDEV-FLSDRFSAKL 229
Cdd:TIGR01271  578 HLDVVTEKEIFEScLCKLMSN--KTRILVTSKL-EHLKKADKILLLHEGVCYFYGTFSELqAKRPDFSSLL 645
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 8-220 6.34e-16

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 76.69  E-value: 6.34e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   8 KTLDGNHgTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDkGRIvvGNRVYFDSHKGFNLP------IQQRK 81
Cdd:PRK09473   23 STPDGDV-TAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAAN-GRI--GGSATFNGREILNLPekelnkLRAEQ 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  82 IGFVFQN--YALFPHLNVYEN---IIFGHSG--DKTRIEEVMALmeLDGL----SKKKIT----ALSGGQAQRVALARAL 146
Cdd:PRK09473   99 ISMIFQDpmTSLNPYMRVGEQlmeVLMLHKGmsKAEAFEESVRM--LDAVkmpeARKRMKmyphEFSGGMRQRVMIAMAL 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1238650805 147 ASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK09473  177 LCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVF 250
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 14-229 7.28e-16

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 75.66  E-value: 7.28e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  14 HGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFNLPiqqrkigfvfqnyalf 92
Cdd:cd03291    48 VGAPVLKnINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGRISFSSQFSWIMP---------------- 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  93 phLNVYENIIFGHSGDKTRI----------EEVMALMELDG--LSKKKITaLSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:cd03291   112 --GTIKENIIFGVSYDEYRYksvvkacqleEDITKFPEKDNtvLGEGGIT-LSGGQRARISLARAVYKDADLYLLDSPFG 188

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 161 ALDGEMRSKLQEE-LKRLIAHfgITAFLVSHDLgEVFKLSDEVICLQDGKIAKRGTPDEV-FLSDRFSAKL 229
Cdd:cd03291   189 YLDVFTEKEIFEScVCKLMAN--KTRILVTSKM-EHLKKADKILILHEGSSYFYGTFSELqSLRPDFSSKL 256
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 20-208 8.60e-16

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 74.78  E-value: 8.60e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfdsHKGFN------------LPIQQRKIGFVFQ 87
Cdd:COG4778    29 GVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILV--------RHDGGwvdlaqaspreiLALRRRTIGYVSQ 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  88 nyalfpHLN----------VYENII---FGHSGDKTRIEEVMALMELD----GLSKkkiTALSGGQAQRVALARALASSP 150
Cdd:COG4778   101 ------FLRviprvsaldvVAEPLLergVDREEARARARELLARLNLPerlwDLPP---ATFSGGEQQRVNIARGFIADP 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1238650805 151 DILLLDEPLSALDGEMRSK---LQEELKR----LIAHFgitaflvsHDLGEVFKLSDEVICLQDG 208
Cdd:COG4778   172 PLLLLDEPTASLDAANRAVvveLIEEAKArgtaIIGIF--------HDEEVREAVADRVVDVTPF 228
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 33-210 1.10e-15

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 76.91  E-value: 1.10e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  33 IFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDShkgfnlpIQQ---RKI-GFVFQNYA-----LFPHLNVYENI-- 101
Cdd:PRK11147   34 LVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIVAR-------LQQdppRNVeGTVYDFVAegieeQAEYLKRYHDIsh 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 102 -------------------IFGHSGD---KTRIEEVMALMELDGlsKKKITALSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:PRK11147  107 lvetdpseknlnelaklqeQLDHHNLwqlENRINEVLAQLGLDP--DAALSSLSGGWLRKAALGRALVSNPDVLLLDEPT 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 160 SALDGEMRSKLQEELKrliaHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:PRK11147  185 NHLDIETIEWLEGFLK----TFQGSIIFISHDRSFIRNMATRIVDLDRGKL 231
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
18-208 3.44e-15

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 75.21  E-value: 3.44e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFD-SHKgfnlPIQQRKIGFVFQNYALFPHLN 96
Cdd:PRK09700   21 LKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKlDHK----LAAQLGIGIIYQELSVIDELT 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 VYENIIFGH------------SGDKTRIEEVMALMELdGLSK---KKITALSGGQAQRVALARALASSPDILLLDEPLSA 161
Cdd:PRK09700   97 VLENLYIGRhltkkvcgvniiDWREMRVRAAMMLLRV-GLKVdldEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSS 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1238650805 162 LDGEMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDG 208
Cdd:PRK09700  176 LTNKEVDYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDRYTVMKDG 221
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 23-205 4.04e-15

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 73.17  E-value: 4.04e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  23 LKLPR-GKFFSIFGKSGAGKTTILRILSGLENPDKGR---------IVVGNR-----VYFDSHKGFNLPIQQRKigfvfQ 87
Cdd:cd03236    20 LPVPReGQVLGLVGPNGIGKSTALKILAGKLKPNLGKfddppdwdeILDEFRgselqNYFTKLLEGDVKVIVKP-----Q 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  88 NYALFPHL---NVYENIifGHSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDG 164
Cdd:cd03236    95 YVDLIPKAvkgKVGELL--KKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDI 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1238650805 165 EMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICL 205
Cdd:cd03236   173 KQRLNAARLIRELAED-DNYVLVVEHDLAVLDYLSDYIHCL 212
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 9-219 6.68e-15

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 74.29  E-value: 6.68e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   9 TLDGNHGTFLLQ-VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFdshkgfNLPIQQR---KIGF 84
Cdd:COG3845   264 SVRDDRGVPALKdVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDIT------GLSPRERrrlGVAY 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  85 V---FQNYALFPHLNVYENIIFGHSG----------DKTRIEEvmalmeldgLSKKKIT--------------ALSGGQA 137
Cdd:COG3845   338 IpedRLGRGLVPDMSVAENLILGRYRrppfsrggflDRKAIRA---------FAEELIEefdvrtpgpdtparSLSGGNQ 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 138 QRVALARALASSPDILLLDEPLSALD-G---EMRSKLQEELKRliahfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKR 213
Cdd:COG3845   409 QKVILARELSRDPKLLIAAQPTRGLDvGaieFIHQRLLELRDA-----GAAVLLISEDLDEILALSDRIAVMYEGRIVGE 483


                  ....*.
gi 1238650805 214 GTPDEV 219
Cdd:COG3845   484 VPAAEA 489
PLN03130 PLN03130
ABC transporter C family member; Provisional
 18-218 9.53e-15

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 74.39  E-value: 9.53e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   18 LLQVSLKLPRGKFFSIFGKSGAGKTTILR-ILSGLENPDKGRIVVGNRVYFdshkgfnLPiqqrKIGFVFqnyalfpHLN 96
Cdd:PLN03130   633 LSNINLDVPVGSLVAIVGSTGEGKTSLISaMLGELPPRSDASVVIRGTVAY-------VP----QVSWIF-------NAT 694

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   97 VYENIIFGHSGDKTRIE---EVMALM-ELDGLSKKKITA-------LSGGQAQRVALARALASSPDILLLDEPLSALDGE 165
Cdd:PLN03130   695 VRDNILFGSPFDPERYEraiDVTALQhDLDLLPGGDLTEigergvnISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAH 774

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805  166 MRSK-----LQEELKrliahfGITAFLVS---HDLGEVfklsDEVICLQDGKIAKRGTPDE 218
Cdd:PLN03130   775 VGRQvfdkcIKDELR------GKTRVLVTnqlHFLSQV----DRIILVHEGMIKEEGTYEE 825
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 13-190 1.66e-14

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 69.49  E-value: 1.66e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  13 NHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIV--VGNRVYFdshkgfnLPiqQRkigfvfqnyA 90
Cdd:cd03223    12 DGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGmpEGEDLLF-------LP--QR---------P 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPHLNVYENIIFghsgdktrieevmALMEldglskkkitALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:cd03223    74 YLPLGTLREQLIY-------------PWDD----------VLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRL 130

                         170       180
                  ....*....|....*....|
gi 1238650805 171 QEELKRLiahfGITAFLVSH 190
Cdd:cd03223   131 YQLLKEL----GITVISVGH 146
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
22-206 2.13e-14

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 70.22  E-value: 2.13e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  22 SLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkgfnlPIQQRKIGFvFQNYALFPHLN----- 96
Cdd:PRK13538   21 SFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGE-----------PIRRQRDEY-HQDLLYLGHQPgikte 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 --VYENIIF----GHSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:PRK13538   89 ltALENLRFyqrlHGPGDDEALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVARL 168

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1238650805 171 QEELKRLIAHFGItAFLVSHDlgEVFKLSDEVICLQ 206
Cdd:PRK13538  169 EALLAQHAEQGGM-VILTTHQ--DLPVASDKVRKLR 201
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 20-224 2.18e-14

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 72.08  E-value: 2.18e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKT-TILRILSGLENPDKgriVVGNRVYFDSHKGFNLPIQQRK------IGFVFQN--YA 90
Cdd:PRK11022   25 RISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDYPGR---VMAEKLEFNGQDLQRISEKERRnlvgaeVAMIFQDpmTS 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPHLNVYENIIFG---HSG--DKTRIEEVMALMELDGL----SKKKITA--LSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:PRK11022  102 LNPCYTVGFQIMEAikvHQGgnKKTRRQRAIDLLNQVGIpdpaSRLDVYPhqLSGGMSQRVMIAMAIACRPKLLIADEPT 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1238650805 160 SALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVFLSDR 224
Cdd:PRK11022  182 TALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRAPR 246
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 33-191 3.68e-14

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 72.07  E-value: 3.68e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  33 IFGKSGAGKTTILRILSGLENPDKGRIVVGnrvyfdshKGFnlpiqqrKIGFVFQNYALFPHLNVYENII--FGHSGDK- 109
Cdd:PRK11819   38 VLGLNGAGKSTLLRIMAGVDKEFEGEARPA--------PGI-------KVGYLPQEPQLDPEKTVRENVEegVAEVKAAl 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 110 TRIEEVMALM-----ELDGLSKK----------------------------------KITALSGGQAQRVALARALASSP 150
Cdd:PRK11819  103 DRFNEIYAAYaepdaDFDALAAEqgelqeiidaadawdldsqleiamdalrcppwdaKVTKLSGGERRRVALCRLLLEKP 182

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1238650805 151 DILLLDEPLSALDGEMRSKLQEELKRliahFGITAFLVSHD 191
Cdd:PRK11819  183 DMLLLDEPTNHLDAESVAWLEQFLHD----YPGTVVAVTHD 219
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 28-208 5.47e-14

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 68.81  E-value: 5.47e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  28 GKFFSIFGKSGAGKTTILRILSGLENpdkGRIVVGNrVYFDshkGFNLPIQ-QRKIGFVFQNYALFPHLNVYENIIFghs 106
Cdd:cd03232    33 GTLTALMGESGAGKTTLLDVLAGRKT---AGVITGE-ILIN---GRPLDKNfQRSTGYVEQQDVHSPNLTVREALRF--- 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 107 gdktrieevmalmeldglsKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHfGITAF 186
Cdd:cd03232   103 -------------------SALLRGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLKKLADS-GQAIL 162

                         170       180
                  ....*....|....*....|...
gi 1238650805 187 LVSHD-LGEVFKLSDEVICLQDG 208
Cdd:cd03232   163 CTIHQpSASIFEKFDRLLLLKRG 185
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 21-210 6.19e-14

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 71.54  E-value: 6.19e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDShkgfNLPIQQRKIGFVFQNYALFPHLNVYEn 100
Cdd:PRK10522  342 INLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAE----QPEDYRKLFSAVFTDFHLFDQLLGPE- 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 iifGHSGDKTRIEEVMALMELDG---LSKKKI--TALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELK 175
Cdd:PRK10522  417 ---GKPANPALVEKWLERLKMAHkleLEDGRIsnLKLSKGQKKRLALLLALAEERDILLLDEWAADQDPHFRREFYQVLL 493

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1238650805 176 RLIAHFGITAFLVSHDlGEVFKLSDEVICLQDGKI 210
Cdd:PRK10522  494 PLLQEMGKTIFAISHD-DHYFIHADRLLEMRNGQL 527
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 18-236 7.00e-14

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 71.30  E-value: 7.00e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDSHKgfnlPIQQRKIGFVFQNYALFPHLN 96
Cdd:PRK10982   14 LDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFqGKEIDFKSSK----EALENGISMVHQELNLVLQRS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 VYENIIFG----------HSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEM 166
Cdd:PRK10982   90 VMDNMWLGryptkgmfvdQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKE 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 167 RSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGK-IAKRG----TPDEVF-------LSDRFSAKLQINGE 234
Cdd:PRK10982  170 VNHLFTIIRKLKER-GCGIVYISHKMEEIFQLCDEITILRDGQwIATQPlaglTMDKIIammvgrsLTQRFPDKENKPGE 248


                  ..
gi 1238650805 235 IL 236
Cdd:PRK10982  249 VI 250
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 18-216 7.26e-14

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 69.06  E-value: 7.26e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNrvyfdshkgfnLPIQQ-------RKIGFVFQNYA 90
Cdd:cd03244    20 LKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDG-----------VDISKiglhdlrSRISIIPQDPV 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPHlNVYENI-IFGHSGDKtRIEEVMALMELDGLSKKKITAL-----------SGGQAQRVALARALASSPDILLLDEP 158
Cdd:cd03244    89 LFSG-TIRSNLdPFGEYSDE-ELWQALERVGLKEFVESLPGGLdtvveeggenlSVGQRQLLCLARALLRKSKILVLDEA 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 159 LSALDGEMRSKLQEELKRLIAHfgITAFLVSHDLGEVFKlSDEVICLQDGKIAKRGTP 216
Cdd:cd03244   167 TASVDPETDALIQKTIREAFKD--CTVLTIAHRLDTIID-SDRILVLDKGRVVEFDSP 221
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
12-218 7.72e-14

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 71.28  E-value: 7.72e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  12 GNHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVvgnrvyFDSHKGFNLPIQ--QRKIGFVFQNY 89
Cdd:PRK10789  325 QTDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIR------FHDIPLTKLQLDswRSRLAVVSQTP 398

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  90 ALFPHlNVYENIIFGH-SGDKTRIEEV--MALMELDGLS---------KKKITALSGGQAQRVALARALASSPDILLLDE 157
Cdd:PRK10789  399 FLFSD-TVANNIALGRpDATQQEIEHVarLASVHDDILRlpqgydtevGERGVMLSGGQKQRISIARALLLNAEILILDD 477

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 158 PLSALDGEMRSKLQEELKRLIAhfGITAFLVSHDLGEVFKlSDEVICLQDGKIAKRGTPDE 218
Cdd:PRK10789  478 ALSAVDGRTEHQILHNLRQWGE--GRTVIISAHRLSALTE-ASEILVMQHGHIAQRGNHDQ 535
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 6-190 8.81e-14

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 68.83  E-value: 8.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   6 FEKTLDGNHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLE--NPDKGRIVVgnrvyFDSHKGFNLPIQQRkig 83
Cdd:COG2401    34 FGVELRVVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDV-----PDNQFGREASLIDA--- 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  84 fvfqnyalfphlnvyeniiFGHSGDKTrieEVMALMELDGLS-----KKKITALSGGQAQRVALARALASSPDILLLDEP 158
Cdd:COG2401   106 -------------------IGRKGDFK---DAVELLNAVGLSdavlwLRRFKELSTGQKFRFRLALLLAERPKLLVIDEF 163

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1238650805 159 LSALDGE----MRSKLQEELKRLiahfGITAFLVSH 190
Cdd:COG2401   164 CSHLDRQtakrVARNLQKLARRA----GITLVVATH 195
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 18-218 8.86e-14

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 71.01  E-value: 8.86e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdshkgfnlPIQQ-------RKIGFVFQNYA 90
Cdd:PRK11160  356 LKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQ-----------PIADyseaalrQAISVVSQRVH 424

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  91 LFPHlNVYENIIFG-HSGDKTRIEEVMALMELDGL--SKKKITA--------LSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:PRK11160  425 LFSA-TLRDNLLLAaPNASDEALIEVLQQVGLEKLleDDKGLNAwlgeggrqLSGGEQRRLGIARALLHDAPLLLLDEPT 503

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 160 SALDGEMRsklQEELKRLIAHF-GITAFLVSHDLGEVFKLsDEVICLQDGKIAKRGTPDE 218
Cdd:PRK11160  504 EGLDAETE---RQILELLAEHAqNKTVLMITHRLTGLEQF-DRICVMDNGQIIEQGTHQE 559
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 21-216 1.04e-13

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 68.59  E-value: 1.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRvyfdSHKGFNLPIQQRKIGFVFQNYALFPHlNVYEN 100
Cdd:cd03369    27 VSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGI----DISTIPLEDLRSSLTIIPQDPTLFSG-TIRSN 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 I-IFGHSGDktriEEVMALMELD--GLSkkkitaLSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKRL 177
Cdd:cd03369   102 LdPFDEYSD----EEIYGALRVSegGLN------LSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTIREE 171

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1238650805 178 IAhfGITAFLVSHDLGEVFKLsDEVICLQDGKIAKRGTP 216
Cdd:cd03369   172 FT--NSTILTIAHRLRTIIDY-DKILVMDAGEVKEYDHP 207
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 21-217 1.33e-13

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 70.83  E-value: 1.33e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGnrvyfDSH--KGFNLPIQQRKIGFVFQNYALFPHlNVY 98
Cdd:PTZ00265   404 LNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIIN-----DSHnlKDINLKWWRSKIGVVSQDPLLFSN-SIK 477

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   99 ENIIFG---------------------HSGDKTR----------IEEVMALMELDGL------------------SKKKI 129
Cdd:PTZ00265   478 NNIKYSlyslkdlealsnyynedgndsQENKNKRnscrakcagdLNDMSNTTDSNELiemrknyqtikdsevvdvSKKVL 557

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  130 --------------------TALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVS 189
Cdd:PTZ00265   558 ihdfvsalpdkyetlvgsnaSKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITIIIA 637

                          250       260
                   ....*....|....*....|....*...
gi 1238650805  190 HDLGEVfKLSDEVICLQDGKIAKRGTPD 217
Cdd:PTZ00265   638 HRLSTI-RYANTIFVLSNRERGSTVDVD 664
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 21-220 1.68e-13

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 68.57  E-value: 1.68e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTtiLRILSGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRKIGFVFQN--YALFPHLNVY 98
Cdd:PRK10418   22 VSLTLQRGRVLALVGGSGSGKS--LTCAAALGILPAGVRQTAGRVLLDGKPVAPCALRGRKIATIMQNprSAFNPLHTMH 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  99 ENII-----FGHSGDKTRIEEVMA---LMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:PRK10418  100 THARetclaLGKPADDATLTAALEavgLENAARVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLDVVAQARI 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1238650805 171 QEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK10418  180 LDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLF 229
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
9-220 2.05e-13

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 69.16  E-value: 2.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   9 TLDGNHGTF--LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDkgRIVVGNRVYFDSHKGFNLPIQQRK----- 81
Cdd:COG4170    12 EIDTPQGRVkaVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDN--WHVTADRFRWNGIDLLKLSPRERRkiigr 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  82 -IGFVFQN--YALFPHLNVYENIIF--------GHSGD--KTRIEEVMALMELDGLSK-KKITA-----LSGGQAQRVAL 142
Cdd:COG4170    90 eIAMIFQEpsSCLDPSAKIGDQLIEaipswtfkGKWWQrfKWRKKRAIELLHRVGIKDhKDIMNsypheLTEGECQKVMI 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 143 ARALASSPDILLLDEPLSAldgeMRSKLQEELKRLIAHF----GITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDE 218
Cdd:COG4170   170 AMAIANQPRLLIADEPTNA----MESTTQAQIFRLLARLnqlqGTSILLISHDLESISQWADTITVLYCGQTVESGPTEQ 245


                  ..
gi 1238650805 219 VF 220
Cdd:COG4170   246 IL 247
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 14-203 3.24e-13

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 66.44  E-value: 3.24e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  14 HGTFLLQVSL-KLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIvvgnrvyfdshkgfnlpiqqrkigfvfqnyalf 92
Cdd:cd03222    10 YGVFFLLVELgVVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDND--------------------------------- 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  93 phlnvyeniifghsgdktrieevmalmELDGLS---KKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSK 169
Cdd:cd03222    57 ---------------------------EWDGITpvyKPQYIDLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLN 109

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1238650805 170 LQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVI 203
Cdd:cd03222   110 AARAIRRLSEEGKKTALVVEHDLAVLDYLSDRIH 143
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
21-211 4.28e-13

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 68.78  E-value: 4.28e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDS-----HKGFNLPIQQRKigfvfqNYALFPH 94
Cdd:PRK11288  272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLdGKPIDIRSprdaiRAGIMLCPEDRK------AEGIIPV 345

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENI-I-----FGHSGD--KTRIEEVMALMELDGLSKK------KITALSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:PRK11288  346 HSVADNInIsarrhHLRAGCliNNRWEAENADRFIRSLNIKtpsreqLIMNLSGGNQQKAILGRWLSEDMKVILLDEPTR 425

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 161 ALDGEMRSKLQEELKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIA 211
Cdd:PRK11288  426 GIDVGAKHEIYNVIYEL-AAQGVAVLFVSSDLPEVLGVADRIVVMREGRIA 475
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 21-219 5.03e-13

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 66.40  E-value: 5.03e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPdkgrIVVGNRVYFDSHKGFNLPIQQRK---IGFVFQNYAlfphlnv 97
Cdd:cd03217    19 VNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKY----EVTEGEILFKGEDITDLPPEERArlgIFLAFQYPP------- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 yeniifghsgdktRIEEVMALMELDGLSKKkitaLSGGQAQRVALARALASSPDILLLDEPLSALD---GEMRSKLQEEL 174
Cdd:cd03217    88 -------------EIPGVKNADFLRYVNEG----FSGGEKKRNEILQLLLLEPDLAILDEPDSGLDidaLRLVAEVINKL 150

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1238650805 175 KRLiahfGITAFLVSHdLGEVFKL--SDEVICLQDGKIAKRGTPDEV 219
Cdd:cd03217   151 REE----GKSVLIITH-YQRLLDYikPDRVHVLYDGRIVKSGDKELA 192
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 25-202 6.33e-13

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 68.66  E-value: 6.33e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  25 LP---RGKFFSIFGKSGAGKTTILRILSGLENPDKGRivvgnrvyfdshkgFNLPIQQRKIGFVFQNYALFPHL-NVYEN 100
Cdd:COG1245    93 LPvpkKGKVTGILGPNGIGKSTALKILSGELKPNLGD--------------YDEEPSWDEVLKRFRGTELQDYFkKLANG 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 II---------------F-GHSGD---KT----RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDE 157
Cdd:COG1245   159 EIkvahkpqyvdlipkvFkGTVRElleKVdergKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDE 238

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1238650805 158 PLSALDGEMRSKLQEELKRLiAHFGITAFLVSHDLGEVFKLSDEV 202
Cdd:COG1245   239 PSSYLDIYQRLNVARLIREL-AEEGKYVLVVEHDLAILDYLADYV 282
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 20-220 1.52e-12

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 67.57  E-value: 1.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKT----TILRIL---SGLENPDKGRIVVGNRVYFDSHKGFNLPIQQRK---IGFVFQN- 88
Cdd:PRK10261   34 NLSFSLQRGETLAIVGESGSGKSvtalALMRLLeqaGGLVQCDKMLLRRRSRQVIELSEQSAAQMRHVRgadMAMIFQEp 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  89 -YALFPHLNVYENI---IFGHSG--------------DKTRIEEVMALMEldglskKKITALSGGQAQRVALARALASSP 150
Cdd:PRK10261  114 mTSLNPVFTVGEQIaesIRLHQGasreeamveakrmlDQVRIPEAQTILS------RYPHQLSGGMRQRVMIAMALSCRP 187

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 151 DILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK10261  188 AVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIF 257
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
35-165 1.63e-12

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 65.26  E-value: 1.63e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  35 GKSGAGKTTILRILSGLENPDKGRIVVgnrvyfDSHKGFNLPiQQRKIGFVFQNYALFPHLNVYENIIF--GHSGDKTR- 111
Cdd:PRK13543   44 GDNGAGKTTLLRVLAGLLHVESGQIQI------DGKTATRGD-RSRFMAYLGHLPGLKADLSTLENLHFlcGLHGRRAKq 116

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1238650805 112 -IEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGE 165
Cdd:PRK13543  117 mPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLE 171
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 27-191 6.27e-12

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 65.74  E-value: 6.27e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  27 RGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRV---YFDSHKGfnlpiqqrkigfvfqnyALFPHLNVYENIIF 103
Cdd:PRK11147  344 RGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCGTKLevaYFDQHRA-----------------ELDPEKTVMDNLAE 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 104 GHsgdktriEEVM-------ALMEL-DGL--SKKKIT---ALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:PRK11147  407 GK-------QEVMvngrprhVLGYLqDFLfhPKRAMTpvkALSGGERNRLLLARLFLKPSNLLILDEPTNDLDVETLELL 479

                         170       180
                  ....*....|....*....|.
gi 1238650805 171 QEelkrLIAHFGITAFLVSHD 191
Cdd:PRK11147  480 EE----LLDSYQGTVLLVSHD 496
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 22-229 7.06e-12

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 65.42  E-value: 7.06e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  22 SLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKG-------RIVvgnRVYFDShkgfnlpiQQRKIGFVFQ--NYALf 92
Cdd:PRK10938   23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGerqsqfsHIT---RLSFEQ--------LQKLVSDEWQrnNTDM- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  93 phLNVYEN--------IIFGHSGDKTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDG 164
Cdd:PRK10938   91 --LSPGEDdtgrttaeIIQDEVKDPARCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDV 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1238650805 165 EMRSKLQEELKRLiAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVfLSDRFSAKL 229
Cdd:PRK10938  169 ASRQQLAELLASL-HQSGITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEI-LQQALVAQL 231
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
18-215 7.62e-12

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 65.51  E-value: 7.62e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNR-VYFDSHKgfnlpIQQRKIGFVFQNYALFPHlN 96
Cdd:PRK10790  357 LQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRpLSSLSHS-----VLRQGVAMVQQDPVVLAD-T 430

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 VYENIIFGHSGDKTRIEEVMALMEL--------DGLSKK---KITALSGGQAQRVALARALASSPDILLLDEPLSALDGE 165
Cdd:PRK10790  431 FLANVTLGRDISEEQVWQALETVQLaelarslpDGLYTPlgeQGNNLSVGQKQLLALARVLVQTPQILILDEATANIDSG 510

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1238650805 166 MRSKLQEELKRLIAHfgITAFLVSHDLGEVFKlSDEVICLQDGKIAKRGT 215
Cdd:PRK10790  511 TEQAIQQALAAVREH--TTLVVIAHRLSTIVE-ADTILVLHRGQAVEQGT 557
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 21-210 8.21e-12

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 65.02  E-value: 8.21e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNR-VYFDS-HKGFNLPI----QQRK-IGFVFQnyalfp 93
Cdd:PRK10762  271 VSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHeVVTRSpQDGLANGIvyisEDRKrDGLVLG------ 344

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  94 hLNVYENI------IFGHSGDKTR-IEEVMALMELDGLSKKK-------ITALSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:PRK10762  345 -MSVKENMsltalrYFSRAGGSLKhADEQQAVSDFIRLFNIKtpsmeqaIGLLSGGNQQKVAIARGLMTRPKVLILDEPT 423

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1238650805 160 SALD-GEmrsklQEELKRLIAHF---GITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:PRK10762  424 RGVDvGA-----KKEIYQLINQFkaeGLSIILVSSEMPEVLGMSDRILVMHEGRI 473
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 33-190 1.48e-11

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 62.20  E-value: 1.48e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  33 IFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDSHKGFnlpiqqrkIGFVFQNYALFPHLNVYENIIFGHS--GDKT 110
Cdd:PRK13541   31 IKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIAKPY--------CTYIGHNLGLKLEMTVFENLKFWSEiyNSAE 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 111 RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRsKLQEELKRLIAHFGITAFLVSH 190
Cdd:PRK13541  103 TLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENR-DLLNNLIVMKANSGGIVLLSSH 181
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 21-211 1.89e-11

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 63.92  E-value: 1.89e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLenpdkgRIVVGNRVYFDSHKGFNLPIQQR-KIGFVF-----QNYALFPH 94
Cdd:PRK15439  282 ISLEVRAGEILGLAGVVGAGRTELAETLYGL------RPARGGRIMLNGKEINALSTAQRlARGLVYlpedrQSSGLYLD 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENI---------IFGHSGDKTRIEEV------MALMELDglskKKITALSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:PRK15439  356 APLAWNVcalthnrrgFWIKPARENAVLERyrralnIKFNHAE----QAARTLSGGNQQKVLIAKCLEASPQLLIVDEPT 431

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 160 SALDGEMRSKLQEELKRlIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIA 211
Cdd:PRK15439  432 RGVDVSARNDIYQLIRS-IAAQNVAVLFISSDLEEIEQMADRVLVMHQGEIS 482
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
25-202 1.91e-11

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 64.06  E-value: 1.91e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  25 LP---RGKFFSIFGKSGAGKTTILRILSGLENPDKGRivVGNRVYFDShkgfnlpIQQRKIGFVFQNYalFPhlNVYENI 101
Cdd:PRK13409   93 LPipkEGKVTGILGPNGIGKTTAVKILSGELIPNLGD--YEEEPSWDE-------VLKRFRGTELQNY--FK--KLYNGE 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 102 I---------------F-GHSGD---KT----RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEP 158
Cdd:PRK13409  160 IkvvhkpqyvdlipkvFkGKVREllkKVdergKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEP 239

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1238650805 159 LSALDGEMRSKLQEELKRLIAhfGITAFLVSHDLGEVFKLSDEV 202
Cdd:PRK13409  240 TSYLDIRQRLNVARLIRELAE--GKYVLVVEHDLAVLDYLADNV 281
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 21-210 3.07e-11

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 63.31  E-value: 3.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLEnpdKGRIvvGNRVYFDSHK-GFNLPIQQRKIGFVF-----QNYALFPH 94
Cdd:TIGR02633 279 VSFSLRRGEILGVAGLVGAGRTELVQALFGAY---PGKF--EGNVFINGKPvDIRNPAQAIRAGIAMvpedrKRHGIVPI 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENIIFGHSGDKTRIEEVMALMELD----GLSKKK---------ITALSGGQAQRVALARALASSPDILLLDEPLSA 161
Cdd:TIGR02633 354 LGVGKNITLSVLKSFCFKMRIDAAAELQiigsAIQRLKvktaspflpIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRG 433

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1238650805 162 LDGEMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:TIGR02633 434 VDVGAKYEIYKLINQLAQE-GVAIIVVSSELAEVLGLSDRVLVIGEGKL 481
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 20-220 3.50e-11

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 63.19  E-value: 3.50e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKT-TILRILSGLENPD----KGRIVVGNRVYFDSHKGFNLPIQQRKIGFVFQN--YALF 92
Cdd:PRK15134   27 DVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPPvvypSGDIRFHGESLLHASEQTLRGVRGNKIAMIFQEpmVSLN 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  93 PHLNV----YENIIF--GHSGDKTRiEEVMALMELDGL--SKKKITA----LSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:PRK15134  107 PLHTLekqlYEVLSLhrGMRREAAR-GEILNCLDRVGIrqAAKRLTDyphqLSGGERQRVMIAMALLTRPELLIADEPTT 185

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 161 ALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEVF 220
Cdd:PRK15134  186 ALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLF 245
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 73-220 3.84e-11

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 63.51  E-value: 3.84e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   73 FNLPIQQRKIGFVFQNYALFpHLNVYENIIFGHSG----DKTRIEEVMALME-LDGLSKKKIT-------ALSGGQAQRV 140
Cdd:PTZ00265  1289 YNLKDLRNLFSIVSQEPMLF-NMSIYENIKFGKEDatreDVKRACKFAAIDEfIESLPNKYDTnvgpygkSLSGGQKQRI 1367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  141 ALARALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVfKLSDEVICLQDGK-----IAKRGT 215
Cdd:PTZ00265  1368 AIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAHRIASI-KRSDKIVVFNNPDrtgsfVQAHGT 1446


                   ....*
gi 1238650805  216 PDEVF 220
Cdd:PTZ00265  1447 HEELL 1451
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
20-163 5.39e-11

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 62.83  E-value: 5.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRI-VVGNRVyfDSHkgfNLPIQQRkIGFVFQNYALFPHLNVY 98
Cdd:NF033858  284 HVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAwLFGQPV--DAG---DIATRRR-VGYMSQAFSLYGELTVR 357

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1238650805  99 ENI-----IFGHSGDKT--RIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALD 163
Cdd:NF033858  358 QNLelharLFHLPAAEIaaRVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD 429
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
20-219 6.78e-11

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 61.74  E-value: 6.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLeNPDKGRiVVGNRVYFDSHKGFNL-PIQQRK-----IGFVFQ--NYAL 91
Cdd:PRK15093   25 RVSMTLTEGEIRGLVGESGSGKSLIAKAICGV-TKDNWR-VTADRMRFDDIDLLRLsPRERRKlvghnVSMIFQepQSCL 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  92 FPHLNVYENII-----FGHSGD-----KTRIEEVMALMELDGLSKKKIT------ALSGGQAQRVALARALASSPDILLL 155
Cdd:PRK15093  103 DPSERVGRQLMqnipgWTYKGRwwqrfGWRKRRAIELLHRVGIKDHKDAmrsfpyELTEGECQKVMIAIALANQPRLLIA 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1238650805 156 DEPLSALDGEMRSKLQEELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:PRK15093  183 DEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKEL 246
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
21-212 9.49e-11

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 62.11  E-value: 9.49e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVV-GNRVYFDShkgfNLPIQQRKIGFVFQNY---ALFPHLN 96
Cdd:PRK09700  282 ISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLnGKDISPRS----PLDAVKKGMAYITESRrdnGFFPNFS 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 VYENI----------------IFGHSGDKTRIEEVMALMELDGLS-KKKITALSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:PRK09700  358 IAQNMaisrslkdggykgamgLFHEVDEQRTAENQRELLALKCHSvNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPT 437

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 160 SALDGEMRSKLQeELKRLIAHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAK 212
Cdd:PRK09700  438 RGIDVGAKAEIY-KVMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQ 489
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
 18-203 1.40e-10

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 59.96  E-value: 1.40e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTI----------LRILSGLENPDKGRIVVGNRVYFDSHKGFN--LPIQQRKIGfv 85
Cdd:cd03270    11 LKNVDVDIPRNKLVVITGVSGSGKSSLafdtiyaegqRRYVESLSAYARQFLGQMDKPDVDSIEGLSpaIAIDQKTTS-- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  86 fQNyalfPH--------LNVYENIIFGHSGDKTRIeEVMALMELDGLS-KKKITALSGGQAQRVALARALASSPD--ILL 154
Cdd:cd03270    89 -RN----PRstvgtvteIYDYLRLLFARVGIRERL-GFLVDVGLGYLTlSRSAPTLSGGEAQRIRLATQIGSGLTgvLYV 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1238650805 155 LDEPLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLgEVFKLSDEVI 203
Cdd:cd03270   163 LDEPSIGLHPRDNDRLIETLKRLRDL-GNTVLVVEHDE-DTIRAADHVI 209
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
109-240 3.57e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 59.75  E-value: 3.57e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 109 KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHfGITAFLV 188
Cdd:NF000106  122 RARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLT 200

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 189 SHDLGEVFKLSDEVICLQDGKIAKRGTPDEVflsdrfsaKLQINGEILKITP 240
Cdd:NF000106  201 TQYMEEAEQLAHELTVIDRGRVIADGKVDEL--------KTKVGGRTLQIRP 244
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 16-210 4.07e-10

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 60.18  E-value: 4.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  16 TFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGnrvyfdshKGFNLP-IQQRKIGFVFQNYALFPH 94
Cdd:PRK10636  326 IILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLA--------KGIKLGyFAQHQLEFLRADESPLQH 397

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 L-----NVYENII------FGHSGDKTrieevmalmeldglskKKITA-LSGGQAQRVALARALASSPDILLLDEPLSAL 162
Cdd:PRK10636  398 LarlapQELEQKLrdylggFGFQGDKV----------------TEETRrFSGGEKARLVLALIVWQRPNLLLLDEPTNHL 461

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1238650805 163 DGEMRSKLQEELkrliAHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:PRK10636  462 DLDMRQALTEAL----IDFEGALVVVSHDRHLLRSTTDDLYLVHDGKV 505
PLN03140 PLN03140
ABC transporter G family member; Provisional
 28-163 4.46e-10

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 60.24  E-value: 4.46e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   28 GKFFSIFGKSGAGKTTILRILSGLENpdkGRIVVGN-RVyfdshKGFnlPIQQ----RKIGFVFQNYALFPHLNVYENII 102
Cdd:PLN03140   906 GVLTALMGVSGAGKTTLMDVLAGRKT---GGYIEGDiRI-----SGF--PKKQetfaRISGYCEQNDIHSPQVTVRESLI 975

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805  103 FG---------HSGDKTR-IEEVMALMELDGLSKK-----KITALSGGQAQRVALARALASSPDILLLDEPLSALD 163
Cdd:PLN03140   976 YSaflrlpkevSKEEKMMfVDEVMELVELDNLKDAivglpGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLD 1051
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 21-203 1.10e-09

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 56.56  E-value: 1.10e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILriLSGLENPDKGRIVVGNRVYFdshkgfnlpiqqrkigfvfqnyalfphlnvYEN 100
Cdd:cd03238    14 LDVSIPLNVLVVVTGVSGSGKSTLV--NEGLYASGKARLISFLPKFS------------------------------RNK 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFghsgdktrIEEVMALMELdGLS----KKKITALSGGQAQRVALARALASSPD--ILLLDEPLSALDGEMRSKLQEEL 174
Cdd:cd03238    62 LIF--------IDQLQFLIDV-GLGyltlGQKLSTLSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQDINQLLEVI 132

                         170       180
                  ....*....|....*....|....*....
gi 1238650805 175 KRLIAHfGITAFLVSHDLgEVFKLSDEVI 203
Cdd:cd03238   133 KGLIDL-GNTVILIEHNL-DVLSSADWII 159
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 21-210 1.69e-09

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 58.02  E-value: 1.69e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLEnpdKGRivVGNRVYFDSHK-GFNLPIQQRKIGFVF-----QNYALFPH 94
Cdd:PRK13549  281 VSFSLRRGEILGIAGLVGAGRTELVQCLFGAY---PGR--WEGEIFIDGKPvKIRNPQQAIAQGIAMvpedrKRDGIVPV 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  95 LNVYENII------FGHSG--DKTRiEEVMALMELDGLSKK------KITALSGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:PRK13549  356 MGVGKNITlaaldrFTGGSriDDAA-ELKTILESIQRLKVKtaspelAIARLSGGNQQKAVLAKCLLLNPKILILDEPTR 434

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 161 ALDgeMRSKLqeELKRLI---AHFGITAFLVSHDLGEVFKLSDEVICLQDGKI 210
Cdd:PRK13549  435 GID--VGAKY--EIYKLInqlVQQGVAIIVISSELPEVLGLSDRVLVMHEGKL 483
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
18-158 1.71e-09

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 58.21  E-value: 1.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfdshkgFNLPIQQR--------KIGFVFQ-- 87
Cdd:NF033858   17 LDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEV-----------LGGDMADArhrravcpRIAYMPQgl 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  88 --NyaLFPHLNVYENI-----IFGHSGD--KTRIEEvmaLMELDGLSK-------KkitaLSGGQAQRVALARALASSPD 151
Cdd:NF033858   86 gkN--LYPTLSVFENLdffgrLFGQDAAerRRRIDE---LLRATGLAPfadrpagK----LSGGMKQKLGLCCALIHDPD 156


                  ....*..
gi 1238650805 152 ILLLDEP 158
Cdd:NF033858  157 LLILDEP 163
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 130-219 1.87e-09

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 58.10  E-value: 1.87e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 130 TALSGGQAQRVALARAL---ASSPDILLLDEPLSALDGEMRSKLQEELKRLIaHFGITAFLVSHDLgEVFKLSDEVICL- 205
Cdd:TIGR00630 828 TTLSGGEAQRIKLAKELskrSTGRTLYILDEPTTGLHFDDIKKLLEVLQRLV-DKGNTVVVIEHNL-DVIKTADYIIDLg 905

                          90
                  ....*....|....*....
gi 1238650805 206 -----QDGKIAKRGTPDEV 219
Cdd:TIGR00630 906 peggdGGGTVVASGTPEEV 924
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 6-219 4.76e-09

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 56.82  E-value: 4.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   6 FEKTLDGNHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRI-VVGNRVYFDSHKGFNlpiqqrkigf 84
Cdd:PRK13545   28 FFRSKDGEYHYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVdIKGSAALIAISSGLN---------- 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  85 vfqnyalfPHLNVYENI-----IFGHSGDKTR--IEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDE 157
Cdd:PRK13545   98 --------GQLTGIENIelkglMMGLTKEKIKeiIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDE 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 158 PLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:PRK13545  170 ALSVGDQTFTKKCLDKMNEFKEQ-GKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEV 230
PLN03073 PLN03073
ABC transporter F family; Provisional
 32-211 5.64e-09

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 56.79  E-value: 5.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  32 SIFGKSGAGKTTILRILSGLENPDKGRIVVGNRV---YFDSHKGFNLPIQQRKIGFVFQNYALFPHLNVYENI-IFGHSG 107
Cdd:PLN03073  539 AMVGPNGIGKSTILKLISGELQPSSGTVFRSAKVrmaVFSQHHVDGLDLSSNPLLYMMRCFPGVPEQKLRAHLgSFGVTG 618

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 108 DktrieevmalmeldgLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMrsklQEELKRLIAHFGITAFL 187
Cdd:PLN03073  619 N---------------LALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDA----VEALIQGLVLFQGGVLM 679

                         170       180
                  ....*....|....*....|....
gi 1238650805 188 VSHDLGEVFKLSDEVICLQDGKIA 211
Cdd:PLN03073  680 VSHDEHLISGSVDELWVVSEGKVT 703
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 21-217 5.83e-09

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 55.46  E-value: 5.83e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLEN--PDKGRIvvgnrvYFDSHKGFNLPIQQRK---IGFVFQNYALFPHL 95
Cdd:COG0396    19 VNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKyeVTSGSI------LLDGEDILELSPDERAragIFLAFQYPVEIPGV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  96 NVYEniiFGHSGDKTRIEEVMALMELDGLSKKKITAL---------------SGGQAQRVALARALASSPDILLLDEPLS 160
Cdd:COG0396    93 SVSN---FLRTALNARRGEELSAREFLKLLKEKMKELgldedfldryvnegfSGGEKKRNEILQMLLLEPKLAILDETDS 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 161 ALD-------GEMRSKLQEElKR---LIAHFG-ITAFLVshdlgevfklSDEVICLQDGKIAKRGTPD 217
Cdd:COG0396   170 GLDidalrivAEGVNKLRSP-DRgilIITHYQrILDYIK----------PDFVHVLVDGRIVKSGGKE 226
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 28-163 6.40e-09

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 56.66  E-value: 6.40e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   28 GKFFSIFGKSGAGKTTILRILSglENPDKGRIVVGNRVYfdshkGFNlPIQ---QRKIGFVFQNYALFPHLNVYENIIFG 104
Cdd:TIGR00956  789 GTLTALMGASGAGKTTLLNVLA--ERVTTGVITGGDRLV-----NGR-PLDssfQRSIGYVQQQDLHLPTSTVRESLRFS 860

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1238650805  105 -------HSGDKTR---IEEVMALMELDGLsKKKITALSGG-----QAQRVALARALASSPDILL-LDEPLSALD 163
Cdd:TIGR00956  861 aylrqpkSVSKSEKmeyVEEVIKLLEMESY-ADAVVGVPGEglnveQRKRLTIGVELVAKPKLLLfLDEPTSGLD 934
PLN03232 PLN03232
ABC transporter C family member; Provisional
 14-227 8.08e-09

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 56.52  E-value: 8.08e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   14 HG-TFLLQVSLKLprgkffSIFGKSGAGKTTILRILSGLENPDKGRIVVGNrvyFDSHKgFNLPIQQRKIGFVFQNYALF 92
Cdd:PLN03232  1253 HGlSFFVSPSEKV------GVVGRTGAGKSSMLNALFRIVELEKGRIMIDD---CDVAK-FGLTDLRRVLSIIPQSPVLF 1322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   93 PHLNVYENIIFGHSGD--------KTRIEEVMAL--MELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSAL 162
Cdd:PLN03232  1323 SGTVRFNIDPFSEHNDadlwealeRAHIKDVIDRnpFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASV 1402

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805  163 DGEMRSKLQ----EELKrliahfGITAFLVSHDLGEVFKlSDEVICLQDGKIAKRGTPDEVfLSDRFSA 227
Cdd:PLN03232  1403 DVRTDSLIQrtirEEFK------SCTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQEL-LSRDTSA 1463
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 33-219 1.14e-08

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 55.89  E-value: 1.14e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   33 IFGKSGAGKTTILRILSGleNPDKGRIVVGNRVYFDSHKGFNlpIQQRKIGFVF---QNYALFPHLNVYENIIF------ 103
Cdd:TIGR00956   92 VLGRPGSGCSTLLKTIAS--NTDGFHIGVEGVITYDGITPEE--IKKHYRGDVVynaETDVHFPHLTVGETLDFaarckt 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  104 -GHSGD----KTRIEEVMAL-MELDGLSKKK--------ITALSGGQAQRVALARALASSPDILLLDEPLSALDG----E 165
Cdd:TIGR00956  168 pQNRPDgvsrEEYAKHIADVyMATYGLSHTRntkvgndfVRGVSGGERKRVSIAEASLGGAKIQCWDNATRGLDSatalE 247

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1238650805  166 MRSKLQEELKRLIAHFGITAFLVSHDlgeVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:TIGR00956  248 FIRALKTSANILDTTPLVAIYQCSQD---AYELFDKVIVLYEGYQIYFGPADKA 298
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 27-191 1.24e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 52.76  E-value: 1.24e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   27 RGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfdshkgfnlpiqqrkigfvfqnyalfphlnvyeniifgHS 106
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY-------------------------------------------ID 37

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  107 GDKTRIEEVMALMELDGLSKKKitALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEE-----LKRLIAHF 181
Cdd:smart00382  38 GEDILEEVLDQLLLIIVGGKKA--SGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLeelrlLLLLKSEK 115

                          170
                   ....*....|
gi 1238650805  182 GITAFLVSHD 191
Cdd:smart00382 116 NLTVILTTND 125
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 7-211 4.30e-08

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 53.97  E-value: 4.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   7 EKTLDGNHGTFLLQ-----VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRI-----VVGNRVYFDS-HKGFNL 75
Cdd:PRK10982  248 EVILEVRNLTSLRQpsirdVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTItlhgkKINNHNANEAiNHGFAL 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  76 PIQQRKIGFVFQNY-----ALFPHLNVYENII--FGHSGDKTRIEEVMALMELDGLSKK-KITALSGGQAQRVALARALA 147
Cdd:PRK10982  328 VTEERRSTGIYAYLdigfnSLISNIRNYKNKVglLDNSRMKSDTQWVIDSMRVKTPGHRtQIGSLSGGNQQKVIIGRWLL 407

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805 148 SSPDILLLDEPLSALDgeMRSKLqeELKRLIAHF-----GItaFLVSHDLGEVFKLSDEVICLQDGKIA 211
Cdd:PRK10982  408 TQPEILMLDEPTRGID--VGAKF--EIYQLIAELakkdkGI--IIISSEMPELLGITDRILVMSNGLVA 470
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 28-215 4.81e-08

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 54.25  E-value: 4.81e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   28 GKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVGNRVYFDShkgfnlpiqqrkIGFVFQNYALFPHLNVYENIIFG--H 105
Cdd:TIGR01257 1965 GECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTN------------ISDVHQNMGYCPQFDAIDDLLTGreH 2032

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  106 SGDKTRIEEVMAlMELDGLSKKKITAL-------------SGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQE 172
Cdd:TIGR01257 2033 LYLYARLRGVPA-EEIEKVANWSIQSLglslyadrlagtySGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWN 2111

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1238650805  173 ELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGT 215
Cdd:TIGR01257 2112 TIVSIIRE-GRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGT 2153
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 33-204 1.25e-07

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 51.07  E-value: 1.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  33 IFGKSGAGKTTILRIL-------------SGLENPD---KGRIVVGNRVYFDSHKGFNLPIQQRkigfvfqnyalfphLN 96
Cdd:cd03240    27 IVGQNGAGKTTIIEALkyaltgelppnskGGAHDPKlirEGEVRAQVKLAFENANGKKYTITRS--------------LA 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  97 VYENIIFGHSGDKTRIEEVMalmeldglskkkITALSGGQ------AQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:cd03240    93 ILENVIFCHQGESNWPLLDM------------RGRCSGGEkvlaslIIRLALAETFGSNCGILALDEPTTNLDEENIEES 160

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1238650805 171 QEELKRLIAHFGI-TAFLVSHDlGEVFKLSDEVIC 204
Cdd:cd03240   161 LAEIIEERKSQKNfQLIVITHD-EELVDAADHIYR 194
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 22-190 2.33e-07

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 51.67  E-value: 2.33e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  22 SLKLPRGKFFSIFGKSGAGKTTILRILSGLEnPdkgriVVGNRVYFDSH-KGFNLPiqQRkigfvfqnyalfPHLNV--- 97
Cdd:TIGR00954 472 SFEVPSGNNLLICGPNGCGKSSLFRILGELW-P-----VYGGRLTKPAKgKLFYVP--QR------------PYMTLgtl 531

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIFGHS---------GDKTrIEEVMALMELDGLSKKKIT---------ALSGGQAQRVALARALASSPDILLLDEPL 159
Cdd:TIGR00954 532 RDQIIYPDSsedmkrrglSDKD-LEQILDNVQLTHILEREGGwsavqdwmdVLSGGEKQRIAMARLFYHKPQFAILDECT 610

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1238650805 160 SALDGEMRSKLQEELKRliahFGITAFLVSH 190
Cdd:TIGR00954 611 SAVSVDVEGYMYRLCRE----FGITLFSVSH 637
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 27-190 2.52e-07

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 51.55  E-value: 2.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  27 RGKFFSIFGKSGAGKTTILRILSGlenpDKGRIVVGNRVYFDSHKGFNLPIQQ--RKIGFVFQNYAL------------- 91
Cdd:PRK10938  285 PGEHWQIVGPNGAGKSTLLSLITG----DHPQGYSNDLTLFGRRRGSGETIWDikKHIGYVSSSLHLdyrvstsvrnvil 360

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  92 ---FPHLNVYENIifghsGDKTRI--EEVMALMELDG-LSKKKITALSGGQaQRVAL-ARALASSPDILLLDEPLSALDG 164
Cdd:PRK10938  361 sgfFDSIGIYQAV-----SDRQQKlaQQWLDILGIDKrTADAPFHSLSWGQ-QRLALiVRALVKHPTLLILDEPLQGLDP 434

                         170       180
                  ....*....|....*....|....*..
gi 1238650805 165 EMRSKLQEELKRLIAHfGITAFL-VSH 190
Cdd:PRK10938  435 LNRQLVRRFVDVLISE-GETQLLfVSH 460
ABC_UvrA_II cd03271
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...
 130-216 3.19e-07

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213238 [Multi-domain]  Cd Length: 261  Bit Score: 50.31  E-value: 3.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 130 TALSGGQAQRVALARAL---ASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLgEVFKLSDEVICL- 205
Cdd:cd03271   168 TTLSGGEAQRIKLAKELskrSTGKTLYILDEPTTGLHFHDVKKLLEVLQRLVDK-GNTVVVIEHNL-DVIKCADWIIDLg 245

                          90
                  ....*....|....*.
gi 1238650805 206 -----QDGKIAKRGTP 216
Cdd:cd03271   246 peggdGGGQVVASGTP 261
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 12-203 1.50e-06

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 47.35  E-value: 1.50e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  12 GNHGTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILsglenpdkGRIVVGNRVYFDSHKGFNLPIQ--QRKIGFVFQny 89
Cdd:cd03227     5 GRFPSYFVPNDVTFGEGSLTIITGPNGSGKSTILDAI--------GLALGGAQSATRRRSGVKAGCIvaAVSAELIFT-- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  90 alfphlnvyeniifghsgdktrieevmalmeldglskkkITALSGGQAQRVALARALASS---PDIL-LLDEPLSALDGE 165
Cdd:cd03227    75 ---------------------------------------RLQLSGGEKELSALALILALAslkPRPLyILDEIDRGLDPR 115

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1238650805 166 MRSKLQEELKRLIAHfGITAFLVSHDLgEVFKLSDEVI 203
Cdd:cd03227   116 DGQALAEAILEHLVK-GAQVIVITHLP-ELAELADKLI 151
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 18-219 1.87e-06

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 49.17  E-value: 1.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVVgnrvyfdshKGFN-----LPIQQRKIGFVFQNYALF 92
Cdd:TIGR00957 1302 LRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIII---------DGLNiakigLHDLRFKITIIPQDPVLF 1372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   93 P---HLNVYEniiFGHSGDktriEEVMALMELDGLsKKKITA---------------LSGGQAQRVALARALASSPDILL 154
Cdd:TIGR00957 1373 SgslRMNLDP---FSQYSD----EEVWWALELAHL-KTFVSAlpdkldhecaeggenLSVGQRQLVCLARALLRKTKILV 1444

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1238650805  155 LDEPLSALDGEMRSKLQEELKrliAHF-GITAFLVSHDLGEVFKLSdEVICLQDGKIAKRGTPDEV 219
Cdd:TIGR00957 1445 LDEATAAVDLETDNLIQSTIR---TQFeDCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNL 1506
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 21-222 2.50e-06

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 48.35  E-value: 2.50e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRI------VVGnrvYF--DSHKGFNlpiqqrkigfvfQNYALF 92
Cdd:PRK15064  338 LNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVkwsenaNIG---YYaqDHAYDFE------------NDLTLF 402

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  93 PHLNVYENiifgHSGDKTRIEEVMALMELDGLS-KKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQ 171
Cdd:PRK15064  403 DWMSQWRQ----EGDDEQAVRGTLGRLLFSQDDiKKSVKVLSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMDMESIESLN 478

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1238650805 172 EELKrliaHFGITAFLVSHDLGEVFKLSDEVICLQDGKIAK-RGTPDEVFLS 222
Cdd:PRK15064  479 MALE----KYEGTLIFVSHDREFVSSLATRIIEITPDGVVDfSGTYEEYLRS 526
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 21-191 4.77e-06

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 47.58  E-value: 4.77e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  21 VSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRivvgnrVYFDSHKgfnlpiqqrKIGFVFQNYALFPHLNVYEN 100
Cdd:PRK15064   20 ISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGN------VSLDPNE---------RLGKLRQDQFAFEEFTVLDT 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 101 IIFGHSG------DKTRI--------EEVMALMEL-------DGLSKKK-------------------ITALSGGQAQRV 140
Cdd:PRK15064   85 VIMGHTElwevkqERDRIyalpemseEDGMKVADLevkfaemDGYTAEAragelllgvgipeeqhyglMSEVAPGWKLRV 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1238650805 141 ALARALASSPDILLLDEPLSALDGEMRSKLQEELKRLIAhfgiTAFLVSHD 191
Cdd:PRK15064  165 LLAQALFSNPDILLLDEPTNNLDINTIRWLEDVLNERNS----TMIIISHD 211
PLN03073 PLN03073
ABC transporter F family; Provisional
 121-163 6.17e-06

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 47.55  E-value: 6.17e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1238650805 121 LDGLS------KKKITALSGGQAQRVALARALASSPDILLLDEPLSALD 163
Cdd:PLN03073  328 LAGLSftpemqVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLD 376
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
18-219 6.72e-06

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 46.35  E-value: 6.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  18 LLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGRIVvgnrvyfdshkgfnlpiQQRKIGFVFQNYALFPHLNV 97
Cdd:PRK13546   40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVD-----------------RNGEVSVIAISAGLSGQLTG 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  98 YENIIF-----GHSGD--KTRIEEVMALMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKL 170
Cdd:PRK13546  103 IENIEFkmlcmGFKRKeiKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKC 182

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1238650805 171 QEELKRLIAHfGITAFLVSHDLGEVFKLSDEVICLQDGKIAKRGTPDEV 219
Cdd:PRK13546  183 LDKIYEFKEQ-NKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDV 230
uvrA PRK00349
excinuclease ABC subunit UvrA;
130-219 9.48e-06

excinuclease ABC subunit UvrA;


Pssm-ID: 234734 [Multi-domain]  Cd Length: 943  Bit Score: 46.99  E-value: 9.48e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 130 TALSGGQAQRVALARALASSPD---ILLLDEPLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLgEVFKLSDEVICL- 205
Cdd:PRK00349  829 TTLSGGEAQRVKLAKELSKRSTgktLYILDEPTTGLHFEDIRKLLEVLHRLVDK-GNTVVVIEHNL-DVIKTADWIIDLg 906

                          90
                  ....*....|....*....
gi 1238650805 206 -----QDGKIAKRGTPDEV 219
Cdd:PRK00349  907 peggdGGGEIVATGTPEEV 925
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 35-210 1.20e-05

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 45.33  E-value: 1.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  35 GKSGAGKTTILRILSGLEnpdKGRIVVGNRVYFDSH--KGFNLPiQQRKIGFVFQNYALFPHLNVYENIIFGHS--GDKT 110
Cdd:cd03233    40 GRPGSGCSTLLKALANRT---EGNVSVEGDIHYNGIpyKEFAEK-YPGEIIYVSEEDVHFPTLTVRETLDFALRckGNEF 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 111 rieevmalmeldglskkkITALSGGQAQRVALARALASSPDILLLDEPLSALDG----EMRSKLqeelkRLIAH-FGITA 185
Cdd:cd03233   116 ------------------VRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSstalEILKCI-----RTMADvLKTTT 172

                         170       180
                  ....*....|....*....|....*.
gi 1238650805 186 FL-VSHDLGEVFKLSDEVICLQDGKI 210
Cdd:cd03233   173 FVsLYQASDEIYDLFDKVLVLYEGRQ 198
PLN03130 PLN03130
ABC transporter C family member; Provisional
 33-233 2.18e-05

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 45.88  E-value: 2.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   33 IFGKSGAGKTTILRILSGLENPDKGRIVVGNrvyFDSHKgFNLPIQQRKIGFVFQNYALFP------------H--LNVY 98
Cdd:PLN03130  1270 IVGRTGAGKSSMLNALFRIVELERGRILIDG---CDISK-FGLMDLRKVLGIIPQAPVLFSgtvrfnldpfneHndADLW 1345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   99 ENIIFGHSGDKTRIEEvmalMELDGLSKKKITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQ----EEL 174
Cdd:PLN03130  1346 ESLERAHLKDVIRRNS----LGLDAEVSEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVDVRTDALIQktirEEF 1421

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1238650805  175 KrliahfGITAFLVSHDLGEVFKlSDEVICLQDGKIAKRGTPDEVFLSDR--FSAKLQING 233
Cdd:PLN03130  1422 K------SCTMLIIAHRLNTIID-CDRILVLDAGRVVEFDTPENLLSNEGsaFSKMVQSTG 1475
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
130-219 3.26e-05

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 45.02  E-value: 3.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 130 TALSGGQAQRVALARALA--SSPDIL-LLDEP---LSALDGEmrsKLQEELKRLIAHfGITAFLVSHDLgEVFKLSDEVI 203
Cdd:COG0178   825 TTLSGGEAQRVKLASELSkrSTGKTLyILDEPttgLHFHDIR---KLLEVLHRLVDK-GNTVVVIEHNL-DVIKTADWII 899

                          90       100
                  ....*....|....*....|..
gi 1238650805 204 CL------QDGKIAKRGTPDEV 219
Cdd:COG0178   900 DLgpeggdGGGEIVAEGTPEEV 921
DLIC pfam05783
Dynein light intermediate chain (DLIC); This family consists of several eukaryotic dynein ...
 20-58 3.62e-05

Dynein light intermediate chain (DLIC); This family consists of several eukaryotic dynein light intermediate chain proteins. The light intermediate chains (LICs) of cytoplasmic dynein consist of multiple isoforms, which undergo post-translational modification to produce a large number of species. DLIC1 is known to be involved in assembly, organization, and function of centrosomes and mitotic spindles when bound to pericentrin. DLIC2 is a subunit of cytoplasmic dynein 2 that may play a role in maintaining Golgi organization by binding cytoplasmic dynein 2 to its Golgi-associated cargo.


Pssm-ID: 368612  Cd Length: 468  Bit Score: 44.83  E-value: 3.62e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1238650805  20 QVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDKGR 58
Cdd:pfam05783  17 RSRSKLPSGKNVLVLGEDGSGKTTLIAKLQGVEHPKKGR 55
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 121-219 2.10e-04

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 42.69  E-value: 2.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 121 LDGLS-KKKITALSGGQAQRVALARALAS--SPDILLLDEPLSALDGEMRSKLQEELKRLiAHFGITAFLVSHDlGEVFK 197
Cdd:TIGR00630 477 LDYLSlSRAAGTLSGGEAQRIRLATQIGSglTGVLYVLDEPSIGLHQRDNRRLINTLKRL-RDLGNTLIVVEHD-EDTIR 554

                          90       100
                  ....*....|....*....|....*...
gi 1238650805 198 LSDEVICL------QDGKIAKRGTPDEV 219
Cdd:TIGR00630 555 AADYVIDIgpgageHGGEVVASGTPEEI 582
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 8-192 3.42e-04

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 41.38  E-value: 3.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   8 KTLDGNHgTFLLQVSLKLPRGKFFSIFGKSGAGKTTILRILSGLENPDkGRIVVgNRVYFDShkgfnLPIQQ-RK-IGFV 85
Cdd:cd03289    11 KYTEGGN-AVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTE-GDIQI-DGVSWNS-----VPLQKwRKaFGVI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  86 FQNYALFP-----HLNVY-----ENI--IFGHSGDKTRIEEVMAlmELDGLSKKKITALSGGQAQRVALARALASSPDIL 153
Cdd:cd03289    83 PQKVFIFSgtfrkNLDPYgkwsdEEIwkVAEEVGLKSVIEQFPG--QLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKIL 160

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1238650805 154 LLDEPLSALDGEMRSKLQEELKRLIAhfGITAFLVSHDL 192
Cdd:cd03289   161 LLDEPSAHLDPITYQVIRKTLKQAFA--DCTVILSEHRI 197
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 129-191 4.40e-04

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 41.69  E-value: 4.40e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1238650805 129 ITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKrliaHFGITAFLVSHD 191
Cdd:PRK10636  147 VSDFSGGWRMRLNLAQALICRSDLLLLDEPTNHLDLDAVIWLEKWLK----SYQGTLILISHD 205
GguA NF040905
sugar ABC transporter ATP-binding protein;
132-158 1.45e-03

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 39.77  E-value: 1.45e-03
                          10        20
                  ....*....|....*....|....*..
gi 1238650805 132 LSGGQAQRVALARALASSPDILLLDEP 158
Cdd:NF040905  405 LSGGNQQKVVLSKWLFTDPDVLILDEP 431
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 84-228 1.75e-03

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 39.81  E-value: 1.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805   84 FVFQNYALFPHLNVYENIifghSGDKTRIEEVMALmeldGLS----KKKITALSGGQAQRVALARALAS--SPDILLLDE 157
Cdd:PRK00635   433 FIFLSQLPSKSLSIEEVL----QGLKSRLSILIDL----GLPyltpERALATLSGGEQERTALAKHLGAelIGITYILDE 504

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1238650805  158 PLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDlGEVFKLSDEVICLQ------DGKIAKRGTPDEvFL--SDRFSAK 228
Cdd:PRK00635   505 PSIGLHPQDTHKLINVIKKLRDQ-GNTVLLVEHD-EQMISLADRIIDIGpgagifGGEVLFNGSPRE-FLakSDSLTAK 580
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 127-233 2.03e-03

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 39.81  E-value: 2.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  127 KKITALSGGQAQRVALARAL---ASSPDILLLDEPLSALDGEMRSKLQEELKRLIAHfGITAFLVSHDLgEVFKLSDEVI 203
Cdd:PRK00635  1695 QNLSSLSLSEKIAIKIAKFLylpPKHPTLFLLDEIATSLDNQQKSALLVQLRTLVSL-GHSVIYIDHDP-ALLKQADYLI 1772

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1238650805  204 CL------QDGKIAKRGTPDEVFLSDRFSAKLQING 233
Cdd:PRK00635  1773 EMgpgsgkTGGKILFSGPPKDISASKDSLLKTYMCN 1808
SbcC_Walker_B pfam13558
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ...
 126-170 2.42e-03

SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.


Pssm-ID: 463921 [Multi-domain]  Cd Length: 90  Bit Score: 36.44  E-value: 2.42e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1238650805 126 KKKITALSGGQAQR---VALARALAS----------SPDILLLDEPLSALDGEMRSKL 170
Cdd:pfam13558  27 YRRSGGLSGGEKQLlayLPLAAALAAqygsaegrppAPRLVFLDEAFAKLDEENIRTA 84
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 129-228 2.78e-03

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 39.43  E-value: 2.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  129 ITALSGGQAQRVALARALASS---PDILLLDEPLSALDGEMRSKLQEELKRLIaHFGITAFLVSHDLgEVFKLSDEVICL 205
Cdd:PRK00635   807 LSSLSGGEIQRLKLAYELLAPskkPTLYVLDEPTTGLHTHDIKALIYVLQSLT-HQGHTVVIIEHNM-HVVKVADYVLEL 884

                           90       100
                   ....*....|....*....|....*....
gi 1238650805  206 ------QDGKIAKRGTPDEVFLSDRFSAK 228
Cdd:PRK00635   885 gpeggnLGGYLLASCSPEELIHLHTPTAK 913
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
129-203 5.61e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 38.12  E-value: 5.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805 129 ITALSGGQ------AQRVALARALASSPDILLLDEPLSALDGEMRSKL----QEELKRLiahfgITAFLVSHDlGEVFKL 198
Cdd:PRK03918  786 LTFLSGGErialglAFRLALSLYLAGNIPLLILDEPTPFLDEERRRKLvdimERYLRKI-----PQVIIVSHD-EELKDA 859


                  ....*
gi 1238650805 199 SDEVI 203
Cdd:PRK03918  860 ADYVI 864
PLN03140 PLN03140
ABC transporter G family member; Provisional
 129-219 6.51e-03

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 37.90  E-value: 6.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1238650805  129 ITALSGGQAQRVALARALASSPDILLLDEPLSALDGEMRSKLQEELKRlIAHFGITAFLVS--HDLGEVFKLSDEVICLQ 206
Cdd:PLN03140   334 IRGISGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQ-IVHLTEATVLMSllQPAPETFDLFDDIILLS 412

                           90
                   ....*....|...
gi 1238650805  207 DGKIAKRGTPDEV 219
Cdd:PLN03140   413 EGQIVYQGPRDHI 425
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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