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Conserved domains on  [gi|1275614724|ref|WP_099707643|]
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MULTISPECIES: IS3 family transposase [unclassified Erwinia]

Protein Classification

transposase family protein( domain architecture ID 1750059)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS3 super family cl41295
IS3 family transposase;
9-372 2.92e-161

IS3 family transposase;


The actual alignment was detected with superfamily member NF033516:

Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 457.03  E-value: 2.92e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724   9 EFKIEAVKQVVDRGYSVASVATRLDITTHSLYAWIKKYGPDSSTHKEQ------SDAQAEIRRLQKELKRVTDERDIFKK 82
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGGEAADAGrlkellTPEEEENRRLKRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724  83 SRGVLRktVRLRYAFIRDNTCCWPVRLLCRVLDVHPSGFYAWLQQPHSQRHQADLRLTGQIKQFWLESGCVYGYRKIHLD 162
Cdd:NF033516   81 ARKLLR--PAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 163 LRDSGQQCGVNRVWRLMKRVGIKAQV--GYRSPRARKGEASIVSPNRLQRQFNPDAPDERWVTDITYIRTHEGWLYLAVV 240
Cdd:NF033516  159 LRREGIRVNHKRVYRLMRELGLLARRrrKRRPYTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAVV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 241 VDLFSRKIIGWSMQSRMTKDIVLNALLMAVWRRNPQKQVLVHSDQGSQYTSHEWQSFLKSHGLEGSMSRRGNCHDNAVAE 320
Cdd:NF033516  239 LDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVAE 318

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1275614724 321 SFFQLLKRERIKKKIYGTREEARSDIFGYIEmFYNSKRRHGSSNQMSPTEYE 372
Cdd:NF033516  319 SFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEFE 369
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
9-372 2.92e-161

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 457.03  E-value: 2.92e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724   9 EFKIEAVKQVVDRGYSVASVATRLDITTHSLYAWIKKYGPDSSTHKEQ------SDAQAEIRRLQKELKRVTDERDIFKK 82
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGGEAADAGrlkellTPEEEENRRLKRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724  83 SRGVLRktVRLRYAFIRDNTCCWPVRLLCRVLDVHPSGFYAWLQQPHSQRHQADLRLTGQIKQFWLESGCVYGYRKIHLD 162
Cdd:NF033516   81 ARKLLR--PAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 163 LRDSGQQCGVNRVWRLMKRVGIKAQV--GYRSPRARKGEASIVSPNRLQRQFNPDAPDERWVTDITYIRTHEGWLYLAVV 240
Cdd:NF033516  159 LRREGIRVNHKRVYRLMRELGLLARRrrKRRPYTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAVV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 241 VDLFSRKIIGWSMQSRMTKDIVLNALLMAVWRRNPQKQVLVHSDQGSQYTSHEWQSFLKSHGLEGSMSRRGNCHDNAVAE 320
Cdd:NF033516  239 LDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVAE 318

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1275614724 321 SFFQLLKRERIKKKIYGTREEARSDIFGYIEmFYNSKRRHGSSNQMSPTEYE 372
Cdd:NF033516  319 SFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
59-377 2.71e-102

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 304.77  E-value: 2.71e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724  59 AQAEIRRLQKELKRVTDERDIFKKSRGVLRKTVRLRYAFIRDNTCCWPVRllcrvldvhpSGFYAWLQQPHSQRHQADLR 138
Cdd:COG2801     3 AEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRAR----------SRRRRRLRRPRSYRADEDAE 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 139 LTGQIKQFWLESGCvYGYRKIHLDLRDSGQQCGVNRVWRLMKRVGIKAQV-GYRSPRARKGEASIVSPNRLqrqFNPDAP 217
Cdd:COG2801    73 LLERIKEIFAESPR-YGYRRITAELRREGIAVNRKRVRRLMRELGLQARRrRKKKYTTYSGHGGPIAPNLL---FTATAP 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 218 DERWVTDITYIRTHEGWLYLAVVVDLFSRKIIGWSMQSRMTKDIVLNALLMAVWRRNPQKQVLVHSDQGSQYTSHEWQSF 297
Cdd:COG2801   149 NQVWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPLILHSDNGSQYTSKAYQEL 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 298 LKSHGLEGSMSRRGNCHDNAVAESFFQLLKRERIKKKIYGTREEARSDIFGYIEmFYNSKRRHGSSNQMSPTEYENQYYQ 377
Cdd:COG2801   229 LKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIE-FYNHERPHSSLGYLTPAEYEKQLAA 307
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 114-381 5.49e-76

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 236.30  E-value: 5.49e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 114 LDVHPSGFYAWLQQPH-----SQRHQADLRLTGQIKQFWLESGCVYGYRKIHLDLRDSGQQCGVNRVWRLMKRVGIKAQV 188
Cdd:PHA02517    1 LGIAPSTYYRCQQQRHhpdkrRARAQHDDWLKSEILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 189 GYRSPRARKGEASIVSPNRLQRQFNPDAPDERWVTDITYIRTHEGWLYLAVVVDLFSRKIIGWSMQSRMTKDIVLNALLM 268
Cdd:PHA02517   81 RGKKVRTTISRKAVAAPDRVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDALEQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 269 AVWRRNPQKQVLVHSDQGSQYTSHEWQSFLKSHGLEGSMSRRGNCHDNAVAESFFQLLKRERIKKKIYGTREEARSDIFG 348
Cdd:PHA02517  161 ALWARGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELATLE 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1275614724 349 YIEmFYNSKRRHGSSNQMSPTEYENQYYQRLGS 381
Cdd:PHA02517  241 WVA-WYNNRRLHERLGYTPPAEAEKAYYASIGN 272
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 217-313 2.27e-33

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 119.73  E-value: 2.27e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 217 PDERWVTDITYIR--THEGWLYLAVVVDLFSRKIIGWSMQSRMTKDIVLNALLMAVWRRNPQKQVlVHSDQGSQYTSHEW 294
Cdd:pfam00665   1 PNQLWQGDFTYIRipGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAFRGGVPLI-IHSDNGSEYTSKAF 79

                          90
                  ....*....|....*....
gi 1275614724 295 QSFLKSHGLEGSMSRRGNC 313
Cdd:pfam00665  80 REFLKDLGIKPSFSRPGNP 98
transpos_IS481 NF033577
IS481 family transposase; null
 105-370 3.43e-18

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 83.79  E-value: 3.43e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 105 WPVRLLCRVLDVHPSGFYAWLQQ---------------PHSQRHQADLRLTGQIKQFWLESGcvYGYRKIHLDLRDSGQQ 169
Cdd:NF033577   14 WSVREAARRFGISRKTVYKWLKRyraggeeglidrsrrPHRSPRRTSPETEARILALRRELR--LGPRRIAYELERQGPG 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 170 CGVNRVWRLMKRVGIKaqvgyRSPRARKGEASIVspnrlqrQFNPDAPDERWVTDITYIRT--HEGWLYLAVVVDLFSRK 247
Cdd:NF033577   92 VSRSTVHRILRRHGLS-----RLRALDRKTGKVK-------RYERAHPGELWHIDIKKLGRipDVGRLYLHTAIDDHSRF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 248 IIGwSMQSRMTKDIVLNALLMAVWRRN-PQKQVLvhSDQGSQYTS--HEWQSFLKSHGLEGSMSRRGNCHDNAVAESFFQ 324
Cdd:NF033577  160 AYA-ELYPDETAETAADFLRRAFAEHGiPIRRVL--TDNGSEFRSraHGFELALAELGIEHRRTRPYHPQTNGKVERFHR 236

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1275614724 325 LLKRERIKKKIYGTREEARSDIFGYIEmFYNSKRRHGSSNQMSPTE 370
Cdd:NF033577  237 TLKDEFAYARPYESLAELQAALDEWLH-HYNHHRPHSALGGKTPAE 281
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
9-372 2.92e-161

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 457.03  E-value: 2.92e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724   9 EFKIEAVKQVVDRGYSVASVATRLDITTHSLYAWIKKYGPDSSTHKEQ------SDAQAEIRRLQKELKRVTDERDIFKK 82
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGGEAADAGrlkellTPEEEENRRLKRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724  83 SRGVLRktVRLRYAFIRDNTCCWPVRLLCRVLDVHPSGFYAWLQQPHSQRHQADLRLTGQIKQFWLESGCVYGYRKIHLD 162
Cdd:NF033516   81 ARKLLR--PAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 163 LRDSGQQCGVNRVWRLMKRVGIKAQV--GYRSPRARKGEASIVSPNRLQRQFNPDAPDERWVTDITYIRTHEGWLYLAVV 240
Cdd:NF033516  159 LRREGIRVNHKRVYRLMRELGLLARRrrKRRPYTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAVV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 241 VDLFSRKIIGWSMQSRMTKDIVLNALLMAVWRRNPQKQVLVHSDQGSQYTSHEWQSFLKSHGLEGSMSRRGNCHDNAVAE 320
Cdd:NF033516  239 LDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVAE 318

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1275614724 321 SFFQLLKRERIKKKIYGTREEARSDIFGYIEmFYNSKRRHGSSNQMSPTEYE 372
Cdd:NF033516  319 SFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
59-377 2.71e-102

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 304.77  E-value: 2.71e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724  59 AQAEIRRLQKELKRVTDERDIFKKSRGVLRKTVRLRYAFIRDNTCCWPVRllcrvldvhpSGFYAWLQQPHSQRHQADLR 138
Cdd:COG2801     3 AEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRAR----------SRRRRRLRRPRSYRADEDAE 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 139 LTGQIKQFWLESGCvYGYRKIHLDLRDSGQQCGVNRVWRLMKRVGIKAQV-GYRSPRARKGEASIVSPNRLqrqFNPDAP 217
Cdd:COG2801    73 LLERIKEIFAESPR-YGYRRITAELRREGIAVNRKRVRRLMRELGLQARRrRKKKYTTYSGHGGPIAPNLL---FTATAP 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 218 DERWVTDITYIRTHEGWLYLAVVVDLFSRKIIGWSMQSRMTKDIVLNALLMAVWRRNPQKQVLVHSDQGSQYTSHEWQSF 297
Cdd:COG2801   149 NQVWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPLILHSDNGSQYTSKAYQEL 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 298 LKSHGLEGSMSRRGNCHDNAVAESFFQLLKRERIKKKIYGTREEARSDIFGYIEmFYNSKRRHGSSNQMSPTEYENQYYQ 377
Cdd:COG2801   229 LKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIE-FYNHERPHSSLGYLTPAEYEKQLAA 307
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 114-381 5.49e-76

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 236.30  E-value: 5.49e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 114 LDVHPSGFYAWLQQPH-----SQRHQADLRLTGQIKQFWLESGCVYGYRKIHLDLRDSGQQCGVNRVWRLMKRVGIKAQV 188
Cdd:PHA02517    1 LGIAPSTYYRCQQQRHhpdkrRARAQHDDWLKSEILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 189 GYRSPRARKGEASIVSPNRLQRQFNPDAPDERWVTDITYIRTHEGWLYLAVVVDLFSRKIIGWSMQSRMTKDIVLNALLM 268
Cdd:PHA02517   81 RGKKVRTTISRKAVAAPDRVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDALEQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 269 AVWRRNPQKQVLVHSDQGSQYTSHEWQSFLKSHGLEGSMSRRGNCHDNAVAESFFQLLKRERIKKKIYGTREEARSDIFG 348
Cdd:PHA02517  161 ALWARGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELATLE 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1275614724 349 YIEmFYNSKRRHGSSNQMSPTEYENQYYQRLGS 381
Cdd:PHA02517  241 WVA-WYNNRRLHERLGYTPPAEAEKAYYASIGN 272
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 217-313 2.27e-33

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 119.73  E-value: 2.27e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 217 PDERWVTDITYIR--THEGWLYLAVVVDLFSRKIIGWSMQSRMTKDIVLNALLMAVWRRNPQKQVlVHSDQGSQYTSHEW 294
Cdd:pfam00665   1 PNQLWQGDFTYIRipGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAFRGGVPLI-IHSDNGSEYTSKAF 79

                          90
                  ....*....|....*....
gi 1275614724 295 QSFLKSHGLEGSMSRRGNC 313
Cdd:pfam00665  80 REFLKDLGIKPSFSRPGNP 98
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
4-87 6.92e-24

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 94.22  E-value: 6.92e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724   4 KRYPEEFKIEAVKQVVDRGYSVASVATRLDITTHSLYAWIKKY----GPDSSTHKEQSDAQAEIRRLQKELKRVTDERDI 79
Cdd:COG2963     6 RRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYreggLGGFPGDGRTTPEQAEIRRLRKELRRLEMENDI 85


                  ....*...
gi 1275614724  80 FKKSRGVL 87
Cdd:COG2963    86 LKKAAALL 93
transpos_IS481 NF033577
IS481 family transposase; null
 105-370 3.43e-18

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 83.79  E-value: 3.43e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 105 WPVRLLCRVLDVHPSGFYAWLQQ---------------PHSQRHQADLRLTGQIKQFWLESGcvYGYRKIHLDLRDSGQQ 169
Cdd:NF033577   14 WSVREAARRFGISRKTVYKWLKRyraggeeglidrsrrPHRSPRRTSPETEARILALRRELR--LGPRRIAYELERQGPG 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 170 CGVNRVWRLMKRVGIKaqvgyRSPRARKGEASIVspnrlqrQFNPDAPDERWVTDITYIRT--HEGWLYLAVVVDLFSRK 247
Cdd:NF033577   92 VSRSTVHRILRRHGLS-----RLRALDRKTGKVK-------RYERAHPGELWHIDIKKLGRipDVGRLYLHTAIDDHSRF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 248 IIGwSMQSRMTKDIVLNALLMAVWRRN-PQKQVLvhSDQGSQYTS--HEWQSFLKSHGLEGSMSRRGNCHDNAVAESFFQ 324
Cdd:NF033577  160 AYA-ELYPDETAETAADFLRRAFAEHGiPIRRVL--TDNGSEFRSraHGFELALAELGIEHRRTRPYHPQTNGKVERFHR 236

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1275614724 325 LLKRERIKKKIYGTREEARSDIFGYIEmFYNSKRRHGSSNQMSPTE 370
Cdd:NF033577  237 TLKDEFAYARPYESLAELQAALDEWLH-HYNHHRPHSALGGKTPAE 281
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 4-71 4.46e-14

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 66.61  E-value: 4.46e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1275614724   4 KRYPEEFKIEAVKQVVDRGYSVASVATRLDITTHSLYAWIKKYGPDSST---HKEQSDAQAEIRRLQKELK 71
Cdd:pfam01527   5 RRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEGGMGAspaRPRLTALEEENRRLKRELA 75
rve_2 pfam13333
Integrase core domain;
320-374 2.21e-11

Integrase core domain;


Pssm-ID: 372570 [Multi-domain]  Cd Length: 52  Bit Score: 58.43  E-value: 2.21e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1275614724 320 ESFFQLLKRERIKKKIYGTREEARSDIFGYIEMfYNSKRRHGssnqMSPTEYENQ 374
Cdd:pfam13333   1 ESFFGSLKTEMVYGEHFKTLEELELAIFDYIEW-YNNKRLKG----LSPVQYRNQ 50
HTH_21 pfam13276
HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding ...
 134-188 8.95e-10

HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.


Pssm-ID: 463824 [Multi-domain]  Cd Length: 60  Bit Score: 54.11  E-value: 8.95e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1275614724 134 QADLRLTGQIKQFWLESGCVYGYRKIHLDLRDSGQ-QCGVNRVWRLMKRVGIKAQV 188
Cdd:pfam13276   1 ELEDELLEAIREIFEESRGTYGYRRITAELRREGGiRVNRKRVARLMRELGLRARR 56
rve_3 pfam13683
Integrase core domain;
301-368 1.80e-09

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 53.37  E-value: 1.80e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1275614724 301 HGLEGSMSRRGNCHDNAVAESFFQLLKRERIKKKIYGTREEARSDIFGYIEMfYNSKRRHGSSNQMSP 368
Cdd:pfam13683   1 LGIEISYIAPGKPMQNGLVESFNGTLRDECLNEHLFSSLAEARALLAAWRED-YNTERPHSSLGYRTP 67
PRK09409 PRK09409
IS2 transposase TnpB; Reviewed
 105-374 7.18e-08

IS2 transposase TnpB; Reviewed


Pssm-ID: 181829 [Multi-domain]  Cd Length: 301  Bit Score: 53.57  E-value: 7.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 105 WPVRLLCRVLDVHPSGFYAWLQQP------HSQRHQADLRLTGQIKQFWLESGcVYGYRKIHLDLRDSGQQCGV-----N 173
Cdd:PRK09409   12 WGVSLVSRCLRVSRAQLHVILRRTddwmdgRRSRHTDDTDVLLRIHHVIGELP-TYGYRRVWALLRRQAELDGMpainaK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 174 RVWRLMKRVGIKAQVGYRSP---RARKGEASIVSPNrlqrqfnpdapdERWVTD-ITYIRTHEGWLYLAVVVDLFSRKII 249
Cdd:PRK09409   91 RVYRIMRQNALLLERKPAVPpskRAHTGRVAVKESN------------QRWCSDgFEFCCDNGERLRVTFALDCCDREAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 250 GWSMQSR-MTKDIVLNALLMAVWRRN----PQKQVLVHSDQGSQYTSHEWQSFLKSHGLEGSMSRRGNCHDNAVAESFFQ 324
Cdd:PRK09409  159 HWAVTTGgFNSETVQDVMLGAVERRFgndlPSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVK 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1275614724 325 LLKRERIKKKIYGTREEARSDIFGYIEmFYNSKRRHGSSNQMSPTEYENQ 374
Cdd:PRK09409  239 TIKRDYISIMPKPDGLTAAKNLAEAFE-HYNEWHPHSALGYRSPREYLRQ 287
PRK14702 PRK14702
insertion element IS2 transposase InsD; Provisional
 154-374 1.27e-06

insertion element IS2 transposase InsD; Provisional


Pssm-ID: 237792 [Multi-domain]  Cd Length: 262  Bit Score: 49.35  E-value: 1.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 154 YGYRKIHLDLRDSGQQCGV-----NRVWRLMKRVGI---KAQVGYRSPRARKGEASIVSPNrlqrqfnpdapdERWVTD- 224
Cdd:PRK14702   27 YGYRRVWALLRRQAELDGMpainaKRVYRLMRQNALlleRKPAVPPSKRAHTGRVAVKESN------------QRWCSDg 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275614724 225 ITYIRTHEGWLYLAVVVDLFSRKIIGWS-----MQSRMTKDIVLNALLMAVWRRNPQKQVLVHSDQGSQYTSHEWQSFLK 299
Cdd:PRK14702   95 FEFCCDNGERLRVTFALDCCDREALHWAvttggFNSETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFAR 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1275614724 300 SHGLEGSMSRRGNCHDNAVAESFFQLLKRERIKKKIYGTREEARSDIFGYIEmFYNSKRRHGSSNQMSPTEYENQ 374
Cdd:PRK14702  175 MLGLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFE-HYNEWHPHSALGYRSPREYLRQ 248
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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