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Conserved domains on  [gi|1275690772|ref|WP_099769415|]
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MULTISPECIES: IS3-like element IS1520 family transposase [Lactobacillales]

Protein Classification

transposase family protein( domain architecture ID 1750059)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS3 super family cl41295
IS3 family transposase;
8-352 1.18e-85

IS3 family transposase;


The actual alignment was detected with superfamily member NF033516:

Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 263.27  E-value: 1.18e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772   8 EFKESIVSLS-QTGRSANSLAKEYNVSVSTVTKWIKQ-------ADPNNTKVLSSNERALI----KENKRLKEELDIFKT 75
Cdd:NF033516    1 EFKLEAVREVlEGGKSVAEVARELGISPSTLYRWRKKyrgggeaADAGRLKELLTPEEEENrrlkRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772  76 SGGAHGKKLIIkgrALVLEvvnanLLAGHRITRILSVLKIPRSTYYDYLHWQPSRTERRRHLIKQEVLTAWLRYPM-YGY 154
Cdd:NF033516   81 ARKLLRPAVKY---ALIDA-----LRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGrYGY 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 155 PRLTILLNQQsDIHVSQRLVYQQMCELGIRSRMVKRINKPTTQTDYDQR--PNLIKQLTDQSG---ILLTDITYIPLNHT 229
Cdd:NF033516  153 RRITALLRRE-GIRVNHKRVYRLMRELGLLARRRRKRRPYTTDSGHVHPvaPNLLNRQFTATRpnqVWVTDITYIRTAEG 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 230 WCYLASV---YNpvtRRVIAYQLNTQMTKELATNVITQVMAQAVKPQ--IIHSDMGSQYTSDLFENTLSKYGIKHSYSRK 304
Cdd:NF033516  232 WLYLAVVldlFS---REIVGWSVSTSMSAELVLDALEMAIEWRGKPEglILHSDNGSQYTSKAYREWLKEHGITQSMSRP 308

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1275690772 305 GQPGDNARIESFHSILKREYVNFQDFKTIHEAIAGIDNYIRWYNSDRI 352
Cdd:NF033516  309 GNCWDNAVAESFFGTLKRECLYRRRFRTLEEARQAIEEYIEFYNHERP 356
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
8-352 1.18e-85

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 263.27  E-value: 1.18e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772   8 EFKESIVSLS-QTGRSANSLAKEYNVSVSTVTKWIKQ-------ADPNNTKVLSSNERALI----KENKRLKEELDIFKT 75
Cdd:NF033516    1 EFKLEAVREVlEGGKSVAEVARELGISPSTLYRWRKKyrgggeaADAGRLKELLTPEEEENrrlkRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772  76 SGGAHGKKLIIkgrALVLEvvnanLLAGHRITRILSVLKIPRSTYYDYLHWQPSRTERRRHLIKQEVLTAWLRYPM-YGY 154
Cdd:NF033516   81 ARKLLRPAVKY---ALIDA-----LRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGrYGY 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 155 PRLTILLNQQsDIHVSQRLVYQQMCELGIRSRMVKRINKPTTQTDYDQR--PNLIKQLTDQSG---ILLTDITYIPLNHT 229
Cdd:NF033516  153 RRITALLRRE-GIRVNHKRVYRLMRELGLLARRRRKRRPYTTDSGHVHPvaPNLLNRQFTATRpnqVWVTDITYIRTAEG 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 230 WCYLASV---YNpvtRRVIAYQLNTQMTKELATNVITQVMAQAVKPQ--IIHSDMGSQYTSDLFENTLSKYGIKHSYSRK 304
Cdd:NF033516  232 WLYLAVVldlFS---REIVGWSVSTSMSAELVLDALEMAIEWRGKPEglILHSDNGSQYTSKAYREWLKEHGITQSMSRP 308

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1275690772 305 GQPGDNARIESFHSILKREYVNFQDFKTIHEAIAGIDNYIRWYNSDRI 352
Cdd:NF033516  309 GNCWDNAVAESFFGTLKRECLYRRRFRTLEEARQAIEEYIEFYNHERP 356
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
56-352 1.93e-63

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 204.23  E-value: 1.93e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772  56 ERALIKENKRLKEELDifktsggahgKKLIIKGRALVLEVVNANLLAGHRITRILSVLKIPRSTYYDYLHWQPSRTERRR 135
Cdd:COG2801     1 ELAEEEELRKEEELLR----------RLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRARSRRRRRLRRPRSYRADED 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 136 HLIKQEVLTAWLRYPMYGYPRLTILLNQQSdIHVSQRLVYQQMCELGIRSRMVKRINKPTTQ-TDYDQRPNLIKQLT--D 212
Cdd:COG2801    71 AELLERIKEIFAESPRYGYRRITAELRREG-IAVNRKRVRRLMRELGLQARRRRKKKYTTYSgHGGPIAPNLLFTATapN 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 213 QsgILLTDITYIPLNHTWCYLASV---YNpvtRRVIAYQLNTQMTKELATNVITQVMAQ--AVKPQIIHSDMGSQYTSDL 287
Cdd:COG2801   150 Q--VWVTDITYIPTAEGWLYLAAVidlFS---REIVGWSVSDSMDAELVVDALEMAIERrgPPKPLILHSDNGSQYTSKA 224

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1275690772 288 FENTLSKYGIKHSYSRKGQPGDNARIESFHSILKREYVNFQDFKTIHEAIAGIDNYIRWYNSDRI 352
Cdd:COG2801   225 YQELLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIEFYNHERP 289
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 113-352 3.98e-38

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 137.69  E-value: 3.98e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 113 LKIPRSTYYDYLHwQPSRTERRR------HLIKQEVLTAW-LRYPMYGYPRLTILLNQQSdIHVSQRLVYQQMCELGIRS 185
Cdd:PHA02517    1 LGIAPSTYYRCQQ-QRHHPDKRRaraqhdDWLKSEILRVYdENHQVYGVRKVWRQLNREG-IRVARCTVGRLMKELGLAG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 186 RMVKRINKPTTQTDYDQRPNLIKQ---LTDQSGILLTDITYIPLNHTWCYLASVYNPVTRRVIAYQLNTQMTKELATNVI 262
Cdd:PHA02517   79 VLRGKKVRTTISRKAVAAPDRVNRqfvATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 263 TQVMAQAVKPQ--IIHSDMGSQYTSDLFENTLSKYGIKHSYSRKGQPGDNARIESFHSILKREYVNFQDFKTIHEAIAGI 340
Cdd:PHA02517  159 EQALWARGRPGglIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELAT 238

                         250
                  ....*....|..
gi 1275690772 341 DNYIRWYNSDRI 352
Cdd:PHA02517  239 LEWVAWYNNRRL 250
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 215-307 2.92e-17

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 76.20  E-value: 2.92e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 215 GILLTDITYIPL--NHTWCYLASVYNPVTRRVIAYQLNTQMTKELATNVITQVMA-QAVKPQIIHSDMGSQYTSDLFENT 291
Cdd:pfam00665   3 QLWQGDFTYIRIpgGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAfRGGVPLIIHSDNGSEYTSKAFREF 82

                          90
                  ....*....|....*.
gi 1275690772 292 LSKYGIKHSYSRKGQP 307
Cdd:pfam00665  83 LKDLGIKPSFSRPGNP 98
transpos_IS6 NF033587
IS6 family transposase;
220-348 5.52e-04

IS6 family transposase;


Pssm-ID: 411209 [Multi-domain]  Cd Length: 203  Bit Score: 40.63  E-value: 5.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 220 DITYIPLNHTWCYLASVYNPVTrRVIAYQLNTQMTKELATNVITQVMAQA-VKPQIIHSDMGSQYT---SDLFENTLSKY 295
Cdd:NF033587   73 DETVIKINGKWYYLYRAVDKEG-ETLDFLLSPRRDTDAAKRFLRKLLKKHdGSPRVILTDKAPSYPaalRRLGLEGRLPR 151

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1275690772 296 GIKHsYSRKGQpgdNARIESFHSILKREYVNFQDFKTIHEAIAGIDNYIRWYN 348
Cdd:NF033587  152 RIEH-RQRKYL---NNLIEQDHRRTKRFINSMLGFKSFRTARRTLAGFEAMYN 200
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
8-352 1.18e-85

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 263.27  E-value: 1.18e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772   8 EFKESIVSLS-QTGRSANSLAKEYNVSVSTVTKWIKQ-------ADPNNTKVLSSNERALI----KENKRLKEELDIFKT 75
Cdd:NF033516    1 EFKLEAVREVlEGGKSVAEVARELGISPSTLYRWRKKyrgggeaADAGRLKELLTPEEEENrrlkRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772  76 SGGAHGKKLIIkgrALVLEvvnanLLAGHRITRILSVLKIPRSTYYDYLHWQPSRTERRRHLIKQEVLTAWLRYPM-YGY 154
Cdd:NF033516   81 ARKLLRPAVKY---ALIDA-----LRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGrYGY 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 155 PRLTILLNQQsDIHVSQRLVYQQMCELGIRSRMVKRINKPTTQTDYDQR--PNLIKQLTDQSG---ILLTDITYIPLNHT 229
Cdd:NF033516  153 RRITALLRRE-GIRVNHKRVYRLMRELGLLARRRRKRRPYTTDSGHVHPvaPNLLNRQFTATRpnqVWVTDITYIRTAEG 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 230 WCYLASV---YNpvtRRVIAYQLNTQMTKELATNVITQVMAQAVKPQ--IIHSDMGSQYTSDLFENTLSKYGIKHSYSRK 304
Cdd:NF033516  232 WLYLAVVldlFS---REIVGWSVSTSMSAELVLDALEMAIEWRGKPEglILHSDNGSQYTSKAYREWLKEHGITQSMSRP 308

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1275690772 305 GQPGDNARIESFHSILKREYVNFQDFKTIHEAIAGIDNYIRWYNSDRI 352
Cdd:NF033516  309 GNCWDNAVAESFFGTLKRECLYRRRFRTLEEARQAIEEYIEFYNHERP 356
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
56-352 1.93e-63

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 204.23  E-value: 1.93e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772  56 ERALIKENKRLKEELDifktsggahgKKLIIKGRALVLEVVNANLLAGHRITRILSVLKIPRSTYYDYLHWQPSRTERRR 135
Cdd:COG2801     1 ELAEEEELRKEEELLR----------RLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRARSRRRRRLRRPRSYRADED 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 136 HLIKQEVLTAWLRYPMYGYPRLTILLNQQSdIHVSQRLVYQQMCELGIRSRMVKRINKPTTQ-TDYDQRPNLIKQLT--D 212
Cdd:COG2801    71 AELLERIKEIFAESPRYGYRRITAELRREG-IAVNRKRVRRLMRELGLQARRRRKKKYTTYSgHGGPIAPNLLFTATapN 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 213 QsgILLTDITYIPLNHTWCYLASV---YNpvtRRVIAYQLNTQMTKELATNVITQVMAQ--AVKPQIIHSDMGSQYTSDL 287
Cdd:COG2801   150 Q--VWVTDITYIPTAEGWLYLAAVidlFS---REIVGWSVSDSMDAELVVDALEMAIERrgPPKPLILHSDNGSQYTSKA 224

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1275690772 288 FENTLSKYGIKHSYSRKGQPGDNARIESFHSILKREYVNFQDFKTIHEAIAGIDNYIRWYNSDRI 352
Cdd:COG2801   225 YQELLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIEFYNHERP 289
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 113-352 3.98e-38

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 137.69  E-value: 3.98e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 113 LKIPRSTYYDYLHwQPSRTERRR------HLIKQEVLTAW-LRYPMYGYPRLTILLNQQSdIHVSQRLVYQQMCELGIRS 185
Cdd:PHA02517    1 LGIAPSTYYRCQQ-QRHHPDKRRaraqhdDWLKSEILRVYdENHQVYGVRKVWRQLNREG-IRVARCTVGRLMKELGLAG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 186 RMVKRINKPTTQTDYDQRPNLIKQ---LTDQSGILLTDITYIPLNHTWCYLASVYNPVTRRVIAYQLNTQMTKELATNVI 262
Cdd:PHA02517   79 VLRGKKVRTTISRKAVAAPDRVNRqfvATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 263 TQVMAQAVKPQ--IIHSDMGSQYTSDLFENTLSKYGIKHSYSRKGQPGDNARIESFHSILKREYVNFQDFKTIHEAIAGI 340
Cdd:PHA02517  159 EQALWARGRPGglIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELAT 238

                         250
                  ....*....|..
gi 1275690772 341 DNYIRWYNSDRI 352
Cdd:PHA02517  239 LEWVAWYNNRRL 250
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 215-307 2.92e-17

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 76.20  E-value: 2.92e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 215 GILLTDITYIPL--NHTWCYLASVYNPVTRRVIAYQLNTQMTKELATNVITQVMA-QAVKPQIIHSDMGSQYTSDLFENT 291
Cdd:pfam00665   3 QLWQGDFTYIRIpgGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAfRGGVPLIIHSDNGSEYTSKAFREF 82

                          90
                  ....*....|....*.
gi 1275690772 292 LSKYGIKHSYSRKGQP 307
Cdd:pfam00665  83 LKDLGIKPSFSRPGNP 98
rve_3 pfam13683
Integrase core domain;
295-351 9.57e-15

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 68.01  E-value: 9.57e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1275690772 295 YGIKHSYSRKGQPGDNARIESFHSILKREYVNFQDFKTIHEAIAGIDNYIRWYNSDR 351
Cdd:pfam13683   1 LGIEISYIAPGKPMQNGLVESFNGTLRDECLNEHLFSSLAEARALLAAWREDYNTER 57
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
4-74 7.85e-13

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 63.79  E-value: 7.85e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772   4 KYSNEFKESIVSLS-QTGRSANSLAKEYNVSVSTVTKWIKQADPNNTKVLSSNE---------RALIKENKRLKEELDIF 73
Cdd:COG2963     7 RYSPEFKAEAVRLVlEGGASVAEVARELGISPSTLYRWVRQYREGGLGGFPGDGrttpeqaeiRRLRKELRRLEMENDIL 86


                  .
gi 1275690772  74 K 74
Cdd:COG2963    87 K 87
HTH_21 pfam13276
HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding ...
 132-190 1.03e-08

HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.


Pssm-ID: 463824 [Multi-domain]  Cd Length: 60  Bit Score: 51.03  E-value: 1.03e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 132 ERRRHLIKQeVLTAWLR-YPMYGYPRLTILLNQQSDIHVSQRLVYQQMCELGIRSRMVKR 190
Cdd:pfam13276   1 ELEDELLEA-IREIFEEsRGTYGYRRITAELRREGGIRVNRKRVARLMRELGLRARRRRK 59
rve_2 pfam13333
Integrase core domain;
314-352 1.75e-07

Integrase core domain;


Pssm-ID: 372570 [Multi-domain]  Cd Length: 52  Bit Score: 47.26  E-value: 1.75e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1275690772 314 ESFHSILKREYVNFQDFKTIHEAIAGIDNYIRWYNSDRI 352
Cdd:pfam13333   1 ESFFGSLKTEMVYGEHFKTLEELELAIFDYIEWYNNKRL 39
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 4-70 1.40e-05

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 42.73  E-value: 1.40e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1275690772   4 KYSNEFKESIVSLS-QTGRSANSLAKEYNVSVSTVTKWIKQ------ADPNNTKVlssneRALIKENKRLKEEL 70
Cdd:pfam01527   6 RFSEEFKLRAVKEVlEPGRTVKEVARRHGVSPNTLYQWRRQyeggmgASPARPRL-----TALEEENRRLKREL 74
Rve COG3316
Transposase (or an inactivated derivative), DDE domain [Mobilome: prophages, transposons];
220-348 2.09e-04

Transposase (or an inactivated derivative), DDE domain [Mobilome: prophages, transposons];


Pssm-ID: 442545 [Multi-domain]  Cd Length: 235  Bit Score: 42.20  E-value: 2.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 220 DITYIPLNHTWCYLASVYNPVTRrVIAYQLNTQMTKELATNVITQVMAQA-VKPQIIHSDMGSQYTSDL-FENTLSKYGI 297
Cdd:COG3316    76 DETYIKIKGKWHYLYRAVDAEGR-ILDFLLSPRRDTKAAKRFLRKALKKYgLKPRVIVTDKLPSYGAALrELKPEGGLGV 154

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1275690772 298 KHSYSRkgqpGDNARIESFHSILKREYVNFQDFKTIHEAIAGIDNYIRWYN 348
Cdd:COG3316   155 EHRQVK----GLNNRIERDHRTLKRRERPMRGFKSFRTAQRFLSGFEAYYN 201
transpos_IS6 NF033587
IS6 family transposase;
220-348 5.52e-04

IS6 family transposase;


Pssm-ID: 411209 [Multi-domain]  Cd Length: 203  Bit Score: 40.63  E-value: 5.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1275690772 220 DITYIPLNHTWCYLASVYNPVTrRVIAYQLNTQMTKELATNVITQVMAQA-VKPQIIHSDMGSQYT---SDLFENTLSKY 295
Cdd:NF033587   73 DETVIKINGKWYYLYRAVDKEG-ETLDFLLSPRRDTDAAKRFLRKLLKKHdGSPRVILTDKAPSYPaalRRLGLEGRLPR 151

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1275690772 296 GIKHsYSRKGQpgdNARIESFHSILKREYVNFQDFKTIHEAIAGIDNYIRWYN 348
Cdd:NF033587  152 RIEH-RQRKYL---NNLIEQDHRRTKRFINSMLGFKSFRTARRTLAGFEAMYN 200
HTH_28 pfam13518
Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is ...
 9-43 1.42e-03

Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.


Pssm-ID: 463908 [Multi-domain]  Cd Length: 52  Bit Score: 36.42  E-value: 1.42e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1275690772   9 FKESIVSLSQTGRSANSLAKEYNVSVSTVTKWIKQ 43
Cdd:pfam13518   1 ERLKIVLLALEGESIKEAARLFGISRSTVYRWIRR 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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